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Thomas Mavromoustakos

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Phenomena

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Differential Scanning Calorimetry

Anatomy

Lipid Bilayers

Chemicals & Drugs

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Publications

TOP 3
Politi Aggeliki; Durdagi Serdar; Moutevelis-Minakakis Panagiota; Kokotos George; Papadopoulos Manthos G; Mavromoustakos Thomas
Application of 3D QSAR CoMFA/CoMSIA and in silico docking studies on novel renin inhibitors against cardiovascular diseases.
Durdagi Serdar; Supuran Claudiu T; Strom T Amanda; Doostdar Nadjmeh; Kumar Mananjali K; Barron Andrew R; Mavromoustakos Thomas; Papadopoulos Manthos G
In silico drug screening approach for the design of magic bullets: a successful example with anti-HIV fullerene derivatized amino acids.
Fotakis Charalambos; Christodouleas Dionisios; Chatzigeorgiou Petros; Zervou Maria; Benetis Nikolas-Ploutarch; Viras Kyriakos; Mavromoustakos Thomas
Development of a CP 31P NMR broadline simulation methodology for studying the interactions of antihypertensive AT1 antagonist losartan with phospholipid bilayers.

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All Publications

2009: Politi Aggeliki; Durdagi Serdar; Moutevelis-Minakakis Panagiota; Kokotos George; Papadopoulos Manthos G; Mavromoustakos Thomas
Application of 3D QSAR CoMFA/CoMSIA and in silico docking studies on novel renin inhibitors against cardiovascular diseases.
European journal of medicinal chemistry 2009;44(9):3703-11.
2009: Durdagi Serdar; Supuran Claudiu T; Strom T Amanda; Doostdar Nadjmeh; Kumar Mananjali K; Barron Andrew R; Mavromoustakos Thomas; Papadopoulos Manthos G
In silico drug screening approach for the design of magic bullets: a successful example with anti-HIV fullerene derivatized amino acids.
Journal of chemical information and modeling 2009;49(5):1139-43.
2009: Fotakis Charalambos; Christodouleas Dionisios; Chatzigeorgiou Petros; Zervou Maria; Benetis Nikolas-Ploutarch; Viras Kyriakos; Mavromoustakos Thomas
Development of a CP 31P NMR broadline simulation methodology for studying the interactions of antihypertensive AT1 antagonist losartan with phospholipid bilayers.
Biophysical journal 2009;96(6):2227-36.
2009: Potamitis Constantinos; Zervou Maria; Katsiaras Vassilis; Zoumpoulakis Panagiotis; Durdagi Serdar; Papadopoulos Manthos G; Hayes Joseph M; Grdadolnik Simona Golic; Kyrikou Ioanna; Argyropoulos Dimitris; Vatougia Georgia; Mavromoustakos Thomas
Antihypertensive drug valsartan in solution and at the AT1 receptor: conformational analysis, dynamic NMR spectroscopy, in silico docking, and molecular dynamics simulations.
Journal of chemical information and modeling 2009;49(3):726-39.
2008: Durdagi Serdar; Mavromoustakos Thomas; Chronakis Nikos; Papadopoulos Manthos G
Computational design of novel fullerene analogues as potential HIV-1 PR inhibitors: Analysis of the binding interactions between fullerene inhibitors and HIV-1 PR residues using 3D QSAR, molecular docking and molecular dynamics simulations.
Bioorganic & medicinal chemistry 2008;16(23):9957-74.
2008: Durdagi Serdar; Mavromoustakos Thomas; Papadopoulos Manthos G
3D QSAR CoMFA/CoMSIA, molecular docking and molecular dynamics studies of fullerene-based HIV-1 PR inhibitors.
Bioorganic & medicinal chemistry letters 2008;18(23):6283-9.
2008: Kapou Agnes; Benetis Nikolas-P; Durdagi Serdar; Nikolaropoulos Sotiris; Mavromoustakos Thomas
3D QSAR/CoMFA and CoMSIA studies on antileukemic steroidal esters coupled with conformationally flexible nitrogen mustards.
Journal of chemical information and modeling 2008;48(11):2254-64.
2008: Koukoulitsa Catherine; Zervou Maria; Demetzos Costas; Mavromoustakos Thomas
Comparative docking studies of labdane-type diterpenes with forskolin at the active site of adenylyl cyclase.
Bioorganic & medicinal chemistry 2008;16(17):8237-43.
2008: Durdagi Serdar; Reis Heribert; Papadopoulos Manthos G; Mavromoustakos Thomas
Comparative molecular dynamics simulations of the potent synthetic classical cannabinoid ligand AMG3 in solution and at binding site of the CB1 and CB2 receptors.
Bioorganic & medicinal chemistry 2008;16(15):7377-87.
2008: Mantzourani Efthimia D; Blokar Klemen; Tselios Theodore V; Matsoukas John M; Platts James A; Mavromoustakos Thomas M; Grdadolnik Simona Golic
A combined NMR and molecular dynamics simulation study to determine the conformational properties of agonists and antagonists against experimental autoimmune encephalomyelitis.
Bioorganic & medicinal chemistry 2008;16(5):2171-82.
2008: Kyrikou Ioanna; Benetis Nikolas P; Chatzigeorgiou Petros; Zervou Maria; Viras Kyriakos; Poulos Constantine; Mavromoustakos Thomas
Interactions of the dipeptide paralysin beta-Ala-Tyr and the aminoacid Glu with phospholipid bilayers.
Biochimica et biophysica acta 2008;1778(1):113-24.
2007: Durdagi Serdar; Papadopoulos Manthos G; Papahatjis Demetris P; Mavromoustakos Thomas
Combined 3D QSAR and molecular docking studies to reveal novel cannabinoid ligands with optimum binding activity.
Bioorganic & medicinal chemistry letters 2007;17(24):6754-63.
2007: Spyranti Zinovia; Dalkas Georgios A; Spyroulias Georgios A; Mantzourani Efthimia D; Mavromoustakos Thomas; Friligou Irene; Matsoukas John M; Tselios Theodore V
Putative bioactive conformations of amide linked cyclic myelin basic protein peptide analogues associated with experimental autoimmune encephalomyelitis.
Journal of medicinal chemistry 2007;50(24):6039-47.
2007: Mantzourani Efthimia D; Platts James A; Brancale Andrea; Mavromoustakos Thomas M; Tselios Theodore V
Molecular dynamics at the receptor level of immunodominant myelin basic protein epitope 87-99 implicated in multiple sclerosis and its antagonists altered peptide ligands: triggering of immune response.
Journal of molecular graphics & modelling 2007;26(2):471-81.
2007: Durdagi Serdar; Kapou Agnes; Kourouli Therapia; Andreou Thanos; Nikas Spyros P; Nahmias Victoria R; Papahatjis Demetris P; Papadopoulos Manthos G; Mavromoustakos Thomas
The application of 3D-QSAR studies for novel cannabinoid ligands substituted at the C1' position of the alkyl side chain on the structural requirements for binding to cannabinoid receptors CB1 and CB2.
Journal of medicinal chemistry 2007;50(12):2875-85.
2007: Kapou Agnes; Benetis Nikolas P; Avlonitis Nikos; Calogeropoulou Theodora; Koufaki Maria; Scoulica Efi; Nikolaropoulos Sotiris S; Mavromoustakos Thomas
3D-Quantitative structure-activity relationships of synthetic antileishmanial ring-substituted ether phospholipids.
Bioorganic & medicinal chemistry 2007;15(3):1252-65.
2007: Mavromoustakos Thomas M
The use of differential scanning calorimetry to study drug-membrane interactions.
Methods in molecular biology (Clifton, N.J.) 2007;400():587-600.
2006: Mantzourani Efthimia D; Tselios Theodore V; Grdadolnik Simona Golic; Platts James A; Brancale Andrea; Deraos George N; Matsoukas John M; Mavromoustakos Thomas M
Comparison of proposed putative active conformations of myelin basic protein epitope 87-99 linear altered peptide ligands by spectroscopic and modelling studies: the role of positions 91 and 96 in T-cell receptor activation.
Journal of medicinal chemistry 2006;49(23):6683-91.
2006: Koukoulitsa C; Kyrikou I; Demetzos C; Mavromoustakos T
The role of the anticancer drug vinorelbine in lipid bilayers using differential scanning calorimetry and molecular modeling.
Chemistry and physics of lipids 2006;144(1):85-95.
2006: Mantzourani E D; Tselios T V; Grdadolnik S Golic; Brancale A; Platts J A; Matsoukas J M; Mavromoustakos T M
A putative bioactive conformation for the altered peptide ligand of myelin basic protein and inhibitor of experimental autoimmune encephalomyelitis [Arg91, Ala96] MBP87-99.
Journal of molecular graphics & modelling 2006;25(1):17-29.
2006: Mavromoustakos T; Moutevelis-Minakakis P; Kokotos C G; Kontogianni P; Politi A; Zoumpoulakis P; Findlay J; Cox A; Balmforth A; Zoga A; Iliodromitis E
Synthesis, binding studies and in vivo biological evaluation of novel non-peptide antihypertensive analogues.
Bioorganic & medicinal chemistry 2006;14(13):4353-60.
2006: Zoumpoulakis Panagiotis; Politi Aggeliki; Grdadolnik Simona Golic; Matsoukas John; Mavromoustakos Thomas
Structure elucidation and conformational study of V8: a novel synthetic non peptide AT(1) antagonist.
Journal of pharmaceutical and biomedical analysis 2006;40(5):1097-104.
2006: Keramida Maria K; Tselios Theodore; Mantzourani Efthimia; Papazisis Kostas; Mavromoustakos Thomas; Klaussen Christian; Agelis George; Deraos Spyros; Friligou Irene; Habibi Hamid; Matsoukas John
Design, synthesis, and molecular modeling of a novel amide-linked cyclic GnRH analogue cyclo(4-9)[Lys4,D-Trp6,Glu9]GnRH: stimulation of gonadotropin gene expression.
Journal of medicinal chemistry 2006;49(1):105-10.
2006: Saroglou V; Hatziantoniou S; Smyrniotakis M; Kyrikou I; Mavromoustakos T; Zompra A; Magafa V; Cordopatis P; Demetzos C
Synthesis, liposomal formulation and thermal effects on phospholipid bilayers of leuprolide.
Journal of peptide science : an official publication of the European Peptide Society 2006;12(1):43-50.
2005: Preto Marco A C; Melo André; Maia Hernâni L S; Mavromoustakos Thomas; Ramos Maria J
Molecular dynamics simulations of angiotensin II in aqueous and dimethyl sulfoxide environments.
The journal of physical chemistry. B 2005;109(37):17743-51.
2005: Souli Charikleia; Avlonitis Nicolaos; Calogeropoulou Theodora; Tsotinis Andrew; Maksay Gábor; Bíró Tímea; Politi Aggeliki; Mavromoustakos Thomas; Makriyannis Alexandros; Reis Heribert; Papadopoulos Manthos
Novel 17beta-substituted conformationally constrained neurosteroids that modulate GABA A receptors.
Journal of medicinal chemistry 2005;48(16):5203-14.
2005: Kapou Agnes; Fousteris Manolis A; Nikolaropoulos Sotiris S; Zervou Maria; Grdadolnik Simona G; Zoumpoulakis Panagiotis; Kyrikou Ioanna; Mavromoustakos Thomas
2D NMR and conformational analysis of a prototype anti-tumour steroidal ester.
Journal of pharmaceutical and biomedical analysis 2005;38(3):428-34.
2005: Petrakis Panos; Touris Ioannis; Liouni Maria; Zervou Maria; Kyrikou Ioanna; Kokkinofta Rebecca; Theocharis Charis R; Mavromoustakos Thomas M
Authenticity of the traditional cypriot spirit "zivania" on the basis of 1h NMR spectroscopy diagnostic parameters and statistical analysis.
Journal of agricultural and food chemistry 2005;53(13):5293-303.
2005: Matsoukas John; Apostolopoulos Vasso; Kalbacher Hubert; Papini Anna-Maria; Tselios Theodore; Chatzantoni Kokona; Biagioli Tiziana; Lolli Francesco; Deraos Spyros; Papathanassopoulos Panagiotis; Troganis Anastassios; Mantzourani Efthimia; Mavromoustakos Thomas; Mouzaki Athanasia
Design and synthesis of a novel potent myelin basic protein epitope 87-99 cyclic analogue: enhanced stability and biological properties of mimics render them a potentially new class of immunomodulators.
Journal of medicinal chemistry 2005;48(5):1470-80.
2005: Kyrikou I; Georgopoulos A; Hatziantoniou S; Mavromoustakos T; Demetzos C
A comparative study of the effects of cholesterol and sclareol, a bioactive labdane type diterpene, on phospholipid bilayers.
Chemistry and physics of lipids 2005;133(2):125-34.
2005: Mantzourani E D; Mavromoustakos T M; Platts J A; Matsoukas J M; Tselios T V
Structural requirements for binding of myelin basic protein (MBP) peptides to MHC II: effects on immune regulation.
Current medicinal chemistry 2005;12(13):1521-35.
2004: Kyrikou I; Hadjikakou S K; Kovala-Demertzi D; Viras K; Mavromoustakos T
Effects of non-steroid anti-inflammatory drugs in membrane bilayers.
Chemistry and physics of lipids 2004;132(2):157-69.
2004: Alexopoulos Kostas; Fatseas Panagiotis; Melissari Euthemia; Vlahakos Demetrios; Roumelioti Panagiota; Mavromoustakos Thomas; Mihailescu Stefan; Paredes-Carbajal Maria Christina; Mascher Dieter; Matsoukas John
Design and synthesis of novel biologically active thrombin receptor non-peptide mimetics based on the pharmacophoric cluster Phe/Arg/NH2 of the Ser42-Phe-Leu-Leu-Arg46 motif sequence: platelet aggregation and relaxant activities.
Journal of medicinal chemistry 2004;47(13):3338-52.
2004: Batsoulis A N; Nacos M K; Pappas C S; Tarantilis P A; Mavromoustakos T; Polissiou M G
Determination of uronic acids in isolated hemicelluloses from kenaf using diffuse reflectance infrared fourier transform spectroscopy (DRIFTS) and the curve-fitting deconvolution method.
Applied spectroscopy 2004;58(2):199-202.
2004: Kyrikou Ioanna; Daliani Ioanna; Mavromoustakos Thomas; Maswadeh Hamzah; Demetzos Costas; Hatziantoniou Sophia; Giatrellis Sarantis; Nounesis George
The modulation of thermal properties of vinblastine by cholesterol in membrane bilayers.
Biochimica et biophysica acta 2004;1661(1):1-8.
2004: Marathias K P; Agroyannis B; Mavromoustakos T; Matsoukas J; Vlahakos D V
Hematocrit-lowering effect following inactivation of renin-angiotensin system with angiotensin converting enzyme inhibitors and angiotensin receptor blockers.
Current topics in medicinal chemistry 2004;4(4):483-6.
2004: Mavromoustakos T; Zoumpoulakis P; Kyrikou I; Zoga A; Siapi E; Zervou M; Daliani I; Dimitriou D; Pitsas A; Kamoutsis C; Laggner P
Efforts to understand the molecular basis of hypertension through drug:membrane interactions.
Current topics in medicinal chemistry 2004;4(4):445-59.
2004: Mavromoustakos T; Zervou M; Zoumpoulakis P; Kyrikou I; Benetis N P; Polevaya L; Roumelioti P; Giatas N; Zoga A; Minakakis P Moutevelis; Kolocouris A; Vlahakos D; Grdadolnik S Golic; Matsoukas J
Conformation and bioactivity. Design and discovery of novel antihypertensive drugs.
Current topics in medicinal chemistry 2004;4(4):385-401.
2003: Kokkinofta Rebecca; Petrakis Panos V; Mavromoustakos Thomas; Theocharis Charis R
Authenticity of the traditional cypriot spirit "zivania" on the basis of metal content using a combination of coupled plasma spectroscopy and statistical analysis.
Journal of agricultural and food chemistry 2003;51(21):6233-9.
2003: Zoumpoulakis P; Daliani I; Zervou M; Kyrikou I; Siapi E; Lamprinidis G; Mikros E; Mavromoustakos T
Losartan's molecular basis of interaction with membranes and AT1 receptor.
Chemistry and physics of lipids 2003;125(1):13-25.
2003: Moutevelis-Minakakis P; Gianni M; Stougiannou H; Zoumpoulakis P; Zoga A; Vlahakos A D; Iliodromitis E; Mavromoustakos T
Design and synthesis of novel antihypertensive drugs.
Bioorganic & medicinal chemistry letters 2003;13(10):1737-40.
2003: Zoumpoulakis P; Zoga A; Roumelioti P; Giatas N; Grdadolnik S G; Iliodromitis E; Vlahakos D; Kremastinos D; Matsoukas J M; Mavromoustakos T
Conformational and biological studies for a pair of novel synthetic AT1 antagonists: stereoelectronic requirements for antihypertensive efficacy.
Journal of pharmaceutical and biomedical analysis 2003;31(5):833-44.
2003: Kyrikou Ioanna; Grdadolnik Simona Golic; Tatari Maria; Poulos Constantine; Mavromoustakos Thomas
Structural elucidation and conformational properties of the toxin paralysin beta-Ala-Tyr.
Journal of pharmaceutical and biomedical analysis 2003;31(4):713-21.
2003: Avlonitis Nikos; Lekka Eleni; Detsi Anastasia; Koufaki Maria; Calogeropoulou Theodora; Scoulica Efi; Siapi Eleni; Kyrikou Ioanna; Mavromoustakos Thomas; Tsotinis Andrew; Grdadolnik Simona Golic; Makriyannis Alexandros
Antileishmanial ring-substituted ether phospholipids.
Journal of medicinal chemistry 2003;46(5):755-67.
2002: Maswadeh H; Demetzos C; Daliani I; Kyrikou I; Mavromoustakos T; Tsortos A; Nounesis G
A molecular basis explanation of the dynamic and thermal effects of vinblastine sulfate upon dipalmitoylphosphatidylcholine bilayer membranes.
Biochimica et biophysica acta 2002;1567(1-2):49-55.
2002: Roumelioti Panagiota; Polevaya Ludmila; Zoumpoulakis Panagiotis; Giatas Nektarios; Mutule Ilze; Keivish Tatjana; Zoga Anastasia; Vlahakos Demetrios; Iliodromitis E; Kremastinos Demetrios; Grdadolnik Simona Golic; Mavromoustakos Thomas; Matsoukas John
Design, synthesis and biological evaluation of cyclic angiotensin II analogues with 3,5 side-chain bridges. Role of C-terminal aromatic residue and ring cluster for activity and implications in the drug design of AT1 non-peptide antagonists.
Bioorganic & medicinal chemistry letters 2002;12(18):2627-33.
2002: Zoumpoulakis Panagiotis; Grdadolnik Simona Golic; Matsoukas John; Mavromoustakos Thomas
Structure elucidation and conformational properties of eprosartan, a non peptide angiotensin II AT1 antagonist.
Journal of pharmaceutical and biomedical analysis 2002;28(1):125-35.
2002: Apostolopoulos V; Matsoukas J; Plebanski M; Mavromoustakos T
Applications of peptide mimetics in cancer.
Current medicinal chemistry 2002;9(4):411-20.
2002: Maswadeh H; Demetzos C; Dimas K; Loukas Y L; Georgopoulos A; Mavromoustakos T; Papaioannou G Th
In-vitro cytotoxic/cytostatic activity of anionic liposomes containing vinblastine against leukaemic human cell lines.
The Journal of pharmacy and pharmacology 2002;54(2):189-96.
2002: Tselios Theodore; Apostolopoulos Vasso; Daliani Ioanna; Deraos Spyros; Grdadolnik Simona; Mavromoustakos Thomas; Melachrinou Maria; Thymianou Sotiria; Probert Lesley; Mouzaki Athanasia; Matsoukas John
Antagonistic effects of human cyclic MBP(87-99) altered peptide ligands in experimental allergic encephalomyelitis and human T-cell proliferation.
Journal of medicinal chemistry 2002;45(2):275-83.
2002: Pappas C; Tarantilis P A; Daliani I; Mavromoustakos T; Polissiou M
Comparison of classical and ultrasound-assisted isolation procedures of cellulose from kenaf (Hibiscus cannabinus L.) and eucalyptus (Eucalyptus rodustrus Sm.).
Ultrasonics sonochemistry 2002;9(1):19-23.
2001: Matsoukas J; Apostolopoulos V; Mavromoustakos T
Designing peptide mimetics for the treatment of multiple sclerosis.
Mini reviews in medicinal chemistry 2001;1(3):273-82.
2001: Mavromoustakos T; Apostolopoulos V; Matsoukas J
Antihypertensive drugs that act on Renin-Angiotensin System with emphasis in AT(1) antagonists.
Mini reviews in medicinal chemistry 2001;1(2):207-17.
2001: Polevaya L; Mavromoustakos T; Zoumboulakis P; Golic Grdadolnik S; Roumelioti P; Giatas N; Mutule I; Keivish T; Vlahakos D V; Iliodromitis E K; Kremastinos D T; Matsoukas J
Synthesis and study of a cyclic angiotensin II antagonist analogue reveals the role of pi*--pi* interactions in the C-terminal aromatic residue for agonist activity and its structure resemblance with AT(1) non-peptide antagonists.
Bioorganic & medicinal chemistry 2001;9(6):1639-47.
2001: Mavromoustakos T; Papahatjis D; Laggner P
Differential membrane fluidization by active and inactive cannabinoid analogues.
Biochimica et biophysica acta 2001;1512(2):183-90.
2001: Mavromoustakos T; Calogeropoulou T; Koufaki M; Kolocouris A; Daliani I; Demetzos C; Meng Z; Makriyannis A; Balzarini J; De Clercq E
Ether phospholipid-AZT conjugates possessing anti-HIV and antitumor cell activity. Synthesis, conformational analysis, and study of their thermal effects on membrane bilayers.
Journal of medicinal chemistry 2001;44(11):1702-9.
2001: Kolocouris A; Mavromoustakos T; Demetzos C; Terzis A; Grdadolnik S G
Structure elucidation and conformational properties of a novel bioactive clerodane diterpene using a combination of high field NMR spectroscopy, computational analysis and X-ray diffraction.
Bioorganic & medicinal chemistry letters 2001;11(6):837-40.
2001: Alexopoulos K; Panagiotopoulos D; Mavromoustakos T; Fatseas P; Paredes-Carbajal M C; Mascher D; Mihailescu S; Matsoukas J
Design, synthesis, and modeling of novel cyclic thrombin receptor-derived peptide analogues of the Ser42-Phe-Leu-Leu-Arg46 motif sequence with fixed conformations of pharmacophoric groups: importance of a Phe/Arg/NH2 cluster for receptor activation and implications in the design of nonpeptide thrombin receptor mimetics.
Journal of medicinal chemistry 2001;44(3):328-39.
2000: Tselios T; Daliani I; Deraos S; Thymianou S; Matsoukas E; Troganis A; Gerothanassis I; Mouzaki A; Mavromoustakos T; Probert L; Matsoukas J
Treatment of experimental allergic encephalomyelitis (EAE) by a rationally designed cyclic analogue of myelin basic protein (MBP) epitope 72-85.
Bioorganic & medicinal chemistry letters 2000;10(24):2713-7.
2000: Roumelioti P; Tselios T; Alexopoulos K; Mavromoustakos T; Kolocouris A; Moore G J; Matsoukas J M
Structural comparison between type I and type II antagonists: possible implications in the drug design of AT1 antagonists.
Bioorganic & medicinal chemistry letters 2000;10(8):755-8.
2000: Matsoukas J M; Polevaya L; Ancans J; Mavromoustakos T; Kolocouris A; Roumelioti P; Vlahakos D V; Yamdagni R; Wu Q; Moore G J
The design and synthesis of a potent Angiotensin II cyclic analogue confirms the ring cluster receptor conformation of the hormone Angiotensin II.
Bioorganic & medicinal chemistry 2000;8(1):1-10.
1999: Kolocouris A; Tataridis D; Fytas G; Mavromoustakos T; Foscolos G B; Kolocouris N; De Clercq E
Synthesis of 2-(2-adamantyl)piperidines and structure anti-influenza virus A activity relationship study using a combination of NMR spectroscopy and molecular modeling.
Bioorganic & medicinal chemistry letters 1999;9(24):3465-70.
1999: Mavromoustakos T; Daliani I
Effects of cannabinoids in membrane bilayers containing cholesterol.
Biochimica et biophysica acta 1999;1420(1-2):252-65.
1999: Alexopoulos K; Fatseas P; Melissari E; Vlahakos D; Smith J; Mavromoustakos T; Saifeddine M; Moore G; Hollenberg M; Matsoukas J
Design and synthesis of thrombin receptor-derived nonpeptide mimetics utilizing a piperazine scaffold.
Bioorganic & medicinal chemistry 1999;7(6):1033-41.
1999: Mavromoustakos T; Kolocouris A; Zervou M; Roumelioti P; Matsoukas J; Weisemann R
An effort to understand the molecular basis of hypertension through the study of conformational analysis of losartan and sarmesin using a combination of nuclear magnetic resonance spectroscopy and theoretical calculations.
Journal of medicinal chemistry 1999;42(10):1714-22.
1999: Tselios T; Probert L; Daliani I; Matsoukas E; Troganis A; Gerothanassis I P; Mavromoustakos T; Moore G J; Matsoukas J M
Design and synthesis of a potent cyclic analogue of the myelin basic protein epitope MBP72-85: importance of the Ala81 carboxyl group and of a cyclic conformation for induction of experimental allergic encephalomyelitis.
Journal of medicinal chemistry 1999;42(7):1170-7.
1999: Mavromoustakos T; Theodoropoulou E; Zervou M; Kourouli T; Papahatjis D
Structure elucidation and conformational properties of synthetic cannabinoids (-)-2-(6a,7,10,10a-tetrahydro-6,6,9-trimethyl-1-hydroxy-6H-dibe nzo [b,d]pyranyl)-2-hexyl-1,3-dithiolane and its methylated analog.
Journal of pharmaceutical and biomedical analysis 1999;18(6):947-56.
1998: Mavromoustakos T; Zervou M; Panagiotopoulos D; Theodoropoulou E; Matsoukas J; Karussis D
Structural elucidation and conformational properties of the immunomodulator linomide.
Journal of pharmaceutical and biomedical analysis 1998;16(5):741-51.
1998: Mavromoustakos T; Stamos I K; Kamoutsis C; Theodoropoulou E; Zervou M; Humpfer E
Nuclear magnetic resonance spectral analysis and conformational properties of 11-benzoyl-9,9a,10,11-tetrahydro-4H-indolo[4,3-ab]carbazole.
Journal of pharmaceutical and biomedical analysis 1998;16(5):723-32.
1998: Alexopoulos K; Matsoukas J; Tselios T; Roumelioti P; Mavromoustakos T; Holada K
A comparative SAR study of thrombin receptor derived non peptide mimetics: importance of phenyl/guanidino proximity for activity.
Amino acids 1998;15(3):211-20.
1998: Mavromoustakos T; Papadopoulos A; Theodoropoulou E; Dimitriou C; Antoniadou-Vyza E
Thermal properties of adamantanol derivatives and their beta-cyclodextrin complexes in phosphatidylcholine bilayers.
Life sciences 1998;62(20):1901-10.
1997: Mavromoustakos T; Theodoropoulou E; Yang D P
The use of high-resolution solid-state NMR spectroscopy and differential scanning calorimetry to study interactions of anaesthetic steroids with membrane.
Biochimica et biophysica acta 1997;1328(1):65-73.
1997: Matsoukas J; Hollenberg M D; Mavromoustakos T; Panagiotopoulos D; Alexopoulos K; Yamdagni R; Wu Q; Moore G J
Conformational analysis of the thrombin receptor agonist peptides SFLLR and SFLLR-NH2 by NMR: evidence for a cyclic bioactive conformation.
Journal of protein chemistry 1997;16(2):113-31.
1996: Mavromoustakos T; Theodoropoulou E; Yang D P; Lin S Y; Koufaki M; Makriyannis A
The conformational properties of the antineoplastic ether lipid 1-thiohexadecyl-2-O-methyl-S-glycero-3-phosphocholine.
Chemistry and physics of lipids 1996;84(1):21-34.
1996: Matsoukas J M; Panagiotopoulos D; Keramida M; Mavromoustakos T; Yamdagni R; Wu Q; Moore G J; Saifeddine M; Hollenberg M D
Synthesis and contractile activities of cyclic thrombin receptor-derived peptide analogues with a Phe-Leu-Leu-Arg motif: importance of the Phe/Arg relative conformation and the primary amino group for activity.
Journal of medicinal chemistry 1996;39(18):3585-91.
1996: Mavromoustakos T; Theodoropoulou E; Papahatjis D; Kourouli T; Yang D P; Trumbore M; Makriyannis A
Studies on the thermotropic effects of cannabinoids on phosphatidylcholine bilayers using differential scanning calorimetry and small angle X-ray diffraction.
Biochimica et biophysica acta 1996;1281(2):235-44.
1996: Mavromoustakos T; Yang D P; Makriyannis A
Topography and thermotropic properties of cannabinoids in brain sphingomyelin bilayers.
Life sciences 1996;59(23):1969-79.
1995: Mavromoustakos T; Yang D P; Makriyannis A
Effects of the anesthetic steroid alphaxalone and its inactive delta 16-analog on the thermotropic properties of membrane bilayers. A model for membrane perturbation.
Biochimica et biophysica acta 1995;1239(2):257-64.
1995: Matsoukas J M; Agelis G; Wahhab A; Hondrelis J; Panagiotopoulos D; Yamdagni R; Wu Q; Mavromoustakos T; Maia H L; Ganter R
Differences in backbone structure between angiotensin II agonists and type I antagonists.
Journal of medicinal chemistry 1995;38(23):4660-9.
1995: Mavromoustakos T; Yang D P; Makriyannis A
Small angle X-ray diffraction and differential scanning calorimetric studies on O-methyl-(-)-delta 8-tetrahydrocannabinol and its 5' iodinated derivative in membrane bilayers.
Biochimica et biophysica acta 1995;1237(2):183-8.
1994: Mavromoustakos T; Yang D P; Makriyannis A
Topography of alphaxalone and delta 16-alphaxalone in membrane bilayers containing cholesterol.
Biochimica et biophysica acta 1994;1194(1):69-74.
1994: Matsoukas J M; Hondrelis J; Keramida M; Mavromoustakos T; Makriyannis A; Yamdagni R; Wu Q; Moore G J
Role of the NH2-terminal domain of angiotensin II (ANG II) and [Sar1]angiotensin II on conformation and activity. NMR evidence for aromatic ring clustering and peptide backbone folding compared with [des-1,2,3]angiotensin II.
The Journal of biological chemistry 1994;269(7):5303-12.
1993: Yang D P; Mavromoustakos T; Makriyannis A
Small angle X-ray diffraction studies of (-)-delta 8-tetrahydrocannabinol and its O-methyl analog in membranes.
Life sciences 1993;53(7):PL117-22.
1992: Yang D P; Mavromoustakos T; Beshah K; Makriyannis A
Amphipathic interactions of cannabinoids with membranes. A comparison between delta 8-THC and its O-methyl analog using differential scanning calorimetry, X-ray diffraction and solid state 2H-NMR.
Biochimica et biophysica acta 1992;1103(1):25-36.
1991: Mavromoustakos T; Yang D P; Broderick W; Fournier D; Makriyannis A
Small angle x-ray diffraction studies on the topography of cannabinoids in synaptic plasma membranes.
Pharmacology, biochemistry, and behavior 1991;40(3):547-52.
1991: Makriyannis A; Yang D P; Mavromoustakos T
Combined use of solid-state nuclear magnetic resonance spectroscopy, small-angle x-ray diffraction, and differential scanning calorimetry in studies of cannabinoid: membrane interactions.
NIDA research monograph 1991;112():106-28.
1990: Mavromoustakos T; Yang D P; Charalambous A; Herbette L G; Makriyannis A
Study of the topography of cannabinoids in model membranes using X-ray diffraction.
Biochimica et biophysica acta 1990;1024(2):336-44.
1990: Makriyannis A; Yang D P; Mavromoustakos T
The molecular features of membrane perturbation by anaesthetic steroids: a study using differential scanning calorimetry, small angle X-ray diffraction and solid state 2H NMR.
Ciba Foundation symposium 1990;153():172-84; discussion 185-9.
1988: Van der Schyf C J; Mavromoustakos T; Makriyannis A
The conformation of (-) 8 alpha and (-) 8 beta-hydroxy-delta 9-tetrahydrocannabinols and their interactions with model membranes.
Life sciences 1988;42(22):2231-9.

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