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Felicity May

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Andrew Axon; Peter G Blain; Luke E Gaughan; Felicity E B May; Faith M Williams; Matthew C Wright
Tartrazine and sunset yellow are xenoestrogens in a new screening assay to identify modulators of human oestrogen receptor transcriptional activity.
Ahmed R H Ahmed; Andrew B Griffiths; Michael T Tilby; Bruce R Westley; Felicity E B May
TFF3 is a normal breast epithelial protein and is associated with differentiated phenotype in early breast cancer but predisposes to invasion and metastasis in advanced disease.
Brendan Dolan; Felicity E B May; Julie Naughton; Nicole Tegtmeyer; Marguerite Clyne
The interaction of Helicobacter pylori with the adherent mucus gel layer secreted by polarized HT29-MTX-E12 cells.

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2012: Andrew Axon; Peter G Blain; Luke E Gaughan; Felicity E B May; Faith M Williams; Matthew C Wright
Tartrazine and sunset yellow are xenoestrogens in a new screening assay to identify modulators of human oestrogen receptor transcriptional activity.
Toxicology 2012;298(1-3):40-51.
2012: Ahmed R H Ahmed; Andrew B Griffiths; Michael T Tilby; Bruce R Westley; Felicity E B May
TFF3 is a normal breast epithelial protein and is associated with differentiated phenotype in early breast cancer but predisposes to invasion and metastasis in advanced disease.
The American journal of pathology 2012;180(3):904-16.
2012: Brendan Dolan; Felicity E B May; Julie Naughton; Nicole Tegtmeyer; Marguerite Clyne
The interaction of Helicobacter pylori with the adherent mucus gel layer secreted by polarized HT29-MTX-E12 cells.
PloS one 2012;7(10):e47300.
2011: David Jamieson; Felicity E B May; Emily V A Mould; Julieann Sludden; Mark W Verrill; Johanne Bray; Nicola Cresti; Eve Famie; Melanie J Griffin; Nahed M Hawsawi; Alan V Boddy
Two minor NQO1 and NQO2 alleles predict poor response of breast cancer patients to adjuvant doxorubicin and cyclophosphamide therapy.
Pharmacogenetics and genomics 2011;21(12):808-19.
2009: GE de Blaquière; Felicity E B May; Bruce R Westley
Increased expression of both insulin receptor substrates 1 and 2 confers increased sensitivity to IGF-1 stimulated cell migration.
Endocrine-related cancer 2009;16(2):635-47.
2009: Felicity E B May; S Michael Griffin; Bruce R Westley
The trefoil factor interacting protein TFIZ1 binds the trefoil protein TFF1 preferentially in normal gastric mucosal cells but the co-expression of these proteins is deregulated in gastric cancer.
The international journal of biochemistry & cell biology 2009;41(3):632-40.
2008: Steven F Moss; Jin-Woo Lee; Edmond Sabo; Anna K Rubin; John Rommel; Bruce R Westley; Felicity E B May; John Gao; Patricia Meitner; Rosemarie Tavares; Murray B Resnick
Decreased expression of gastrokine 1 and the trefoil factor interacting protein TFIZ1/GKN2 in gastric cancer: influence of tumor histology and relationship to prognosis.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(13):4161-7.
2007: Peti Thuwajit; Watinee Chawengrattanachot; Chanitra Thuwajit; Banchob Sripa; Felicity E B May; Bruce R Westley; Nisana Tepsiri; Anucha Paupairoj; Siri Chau-in
Increased TFF1 trefoil protein expression in Opisthorchis viverrini-associated cholangiocarcinoma is important for invasive promotion.
Hepatology research : the official journal of the Japan Society of Hepatology 2007;37(4):295-304.
2006: C Emma Johns; Julia L Newton; Bruce R Westley; Felicity E B May
Human pancreatic polypeptide has a marked diurnal rhythm that is affected by ageing and is associated with the gastric TFF2 circadian rhythm.
Peptides 2006;27(6):1341-8.
2006: Bruce R Westley; Felicity E B May
Identification of steroid hormone-regulated genes in breast cancer.
Methods in molecular medicine 2006;120():363-88.
2005: L Thim; Felicity E B May
Structure of mammalian trefoil factors and functional insights.
Cellular and molecular life sciences : CMLS 2005;62(24):2956-73.
2005: Somchai Chutipongtanate; Yasushi Nakagawa; Suchai Sritippayawan; Jeeraporn Pittayamateekul; Paisal Parichatikanond; Bruce R Westley; Felicity E B May; Prida Malasit; Visith Thongboonkerd
Identification of human urinary trefoil factor 1 as a novel calcium oxalate crystal growth inhibitor.
The Journal of clinical investigation 2005;115(12):3613-22.
2005: Pierre-Olivier Lafontaine; Murielle Arnal; Nelly Buron; Eric Solary; Alain M Bron; Bruce R Westley; Felicity E B May; Jacques Bara; Christian Gespach; Catherine Creuzot-Garcher
Trefoil factor family mRNA and protein expression in pterygium.
International journal of oncology 2005;27(4):997-1003.
2005: C Emma Johns; Julia L Newton; Bruce R Westley; Felicity E B May
The diurnal rhythm of the cytoprotective human trefoil protein TFF2 is reduced by factors associated with gastric mucosal damage: ageing, Helicobacter pylori infection, and sleep deprivation.
The American journal of gastroenterology 2005;100(7):1491-7.
2005: Bruce R Westley; S Michael Griffin; Felicity E B May
Interaction between TFF1, a gastric tumor suppressor trefoil protein, and TFIZ1, a brichos domain-containing protein with homology to SP-C.
Biochemistry 2005;44(22):7967-75.
2004: Rosalia Carrasco; Miguel Pera; Felicity E B May; Bruce R Westley; Antonio Martinez; Luis Morales
Trefoil factor family peptide 3 prevents the development and promotes healing of ischemia-reperfusion injury in weanling rats.
Journal of pediatric surgery 2004;39(11):1693-700.
2004: M-H Ruchaud-Sparagano; Bruce R Westley; Felicity E B May
The trefoil protein TFF1 is bound to MUC5AC in human gastric mucosa.
Cellular and molecular life sciences : CMLS 2004;61(15):1946-54.
2004: Marguerite Clyne; Paul Dillon; Stephen Daly; Richard O'Kennedy; Felicity E B May; Bruce R Westley; Brendan Drumm
Helicobacter pylori interacts with the human single-domain trefoil protein TFF1.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(19):7409-14.
2004: Felicity E B May; Jennifer I Semple; Sara J Prest; Bruce R Westley
Expression and motogenic activity of TFF2 in human breast cancer cells.
Peptides 2004;25(5):865-72.
2004: Anthony J FitzGerald; M Pu; Tania Marchbank; Bruce R Westley; Felicity E B May; J Boyle; M Yadollahi-Farsani; Subrata Ghosh; Raymond J Playford
Synergistic effects of systemic trefoil factor family 1 (TFF1) peptide and epidermal growth factor in a rat model of colitis.
Peptides 2004;25(5):793-801.
2004: M Pu; Felicity E B May; R J Playford; M-H Ruchaud-Sparagano; Bruce R Westley
Development of a two-site ELISA assay for the dimeric form of human TFF1.
Peptides 2004;25(5):731-6.
2004: Antonio Soriano-Izquierdo; Meritxell Gironella; Anna Massaguer; Felicity E B May; Antonio Salas; Miquel Sans; Richard Poulsom; Lars Thim; Josep M Piqué; Julián Panés
Trefoil peptide TFF2 treatment reduces VCAM-1 expression and leukocyte recruitment in experimental intestinal inflammation.
Journal of leukocyte biology 2004;75(2):214-23.
2004: Julia L Newton; C E Johns; Felicity E B May
Review article: the ageing bowel and intolerance to aspirin.
Alimentary pharmacology & therapeutics 2004;19(1):39-45.
2003: Frederick W Muskett; Felicity E B May; Bruce R Westley; James Feeney
Solution structure of the disulfide-linked dimer of human intestinal trefoil factor (TFF3): the intermolecular orientation and interactions are markedly different from those of other dimeric trefoil proteins.
Biochemistry 2003;42(51):15139-47.
2003: Sylvie Rodrigues; Samir Attoub; Quang-Dé Nguyen; Erik Bruyneel; Christelle M Rodrigue; Bruce R Westley; Felicity E B May; Lars Thim; Marc Mareel; Shahin Emami; Christian Gespach
Selective abrogation of the proinvasive activity of the trefoil peptides pS2 and spasmolytic polypeptide by disruption of the EGF receptor signaling pathways in kidney and colonic cancer cells.
Oncogene 2003;22(29):4488-97.
2003: Felicity E B May; Stephen T Church; Sarah Major; Bruce R Westley
The closely related estrogen-regulated trefoil proteins TFF1 and TFF3 have markedly different hydrodynamic properties, overall charge, and distribution of surface charge.
Biochemistry 2003;42(27):8250-9.
2003: Sylvie Rodrigues; Elisabeth Van Aken; Saskia Van Bocxlaer; Samir Attoub; Quang-Dé Nguyen; Erik Bruyneel; Bruce R Westley; Felicity E B May; Lars Thim; Marc Mareel; Christian Gespach; Shahin Emami
Trefoil peptides as proangiogenic factors in vivo and in vitro: implication of cyclooxygenase-2 and EGF receptor signaling.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003;17(1):7-16.
2002: Sara J Prest; Felicity E B May; Bruce R Westley
The estrogen-regulated protein, TFF1, stimulates migration of human breast cancer cells.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002;16(6):592-4.
2001: M Crosier; D Scott; R G Wilson; C D Griffiths; Felicity E B May; Bruce R Westley
High expression of the trefoil protein TFF1 in interval breast cancers.
The American journal of pathology 2001;159(1):215-21.
2001: Jennifer I Semple; Julia L Newton; Bruce R Westley; Felicity E B May
Dramatic diurnal variation in the concentration of the human trefoil peptide TFF2 in gastric juice.
Gut 2001;48(5):648-55.
2001: M A Williams; Bruce R Westley; Felicity E B May; James Feeney
The solution structure of the disulphide-linked homodimer of the human trefoil protein TFF1.
FEBS letters 2001;493(2-3):70-4.
2000: C A Molloy; Felicity E B May; Bruce R Westley
Insulin receptor substrate-1 expression is regulated by estrogen in the MCF-7 human breast cancer cell line.
The Journal of biological chemistry 2000;275(17):12565-71.
2000: Felicity E B May; Jennifer I Semple; Julia L Newton; Bruce R Westley
The human two domain trefoil protein, TFF2, is glycosylated in vivo in the stomach.
Gut 2000;46(4):454-9.
2000: Julia L Newton; Adrian Allen; Bruce R Westley; Felicity E B May
The human trefoil peptide, TFF1, is present in different molecular forms that are intimately associated with mucus in normal stomach.
Gut 2000;46(3):312-20.
1999: C Donaghue; Bruce R Westley; Felicity E B May
Selective promoter usage of the human estrogen receptor-alpha gene and its regulation by estrogen.
Molecular endocrinology (Baltimore, Md.) 1999;13(11):1934-50.
1999: M Crosier; D Scott; R G Wilson; C D Griffiths; Felicity E B May; Bruce R Westley
Differences in Ki67 and c-erbB2 expression between screen-detected and true interval breast cancers.
Clinical cancer research : an official journal of the American Association for Cancer Research 1999;5(10):2682-8.
1999: DP Calnan; Bruce R Westley; Felicity E B May; DN Floyd; Tania Marchbank; Raymond J Playford
The trefoil peptide TFF1 inhibits the growth of the human gastric adenocarcinoma cell line AGS.
The Journal of pathology 1999;188(3):312-7.
1999: Bruce R Westley; Felicity E B May
Prognostic value of cathepsin D in breast cancer.
British journal of cancer 1999;79(2):189-90.
1998: Tania Marchbank; Bruce R Westley; Felicity E B May; DP Calnan; Raymond J Playford
Dimerization of human pS2 (TFF1) plays a key role in its protective/healing effects.
The Journal of pathology 1998;185(2):153-8.
1998: Bruce R Westley; S J Clayton; Michael Daws; C A Molloy; Felicity E B May
Interactions between the oestrogen and insulin-like growth factor signalling pathways in the control of breast epithelial cell proliferation.
Biochemical Society symposium 1998;63():35-44.
1997: M P Chadwick; Bruce R Westley; Felicity E B May
Homodimerization and hetero-oligomerization of the single-domain trefoil protein pNR-2/pS2 through cysteine 58.
The Biochemical journal 1997;327 ( Pt 1)():117-23.
1997: Felicity E B May; Bruce R Westley
Trefoil proteins: their role in normal and malignant cells.
The Journal of pathology 1997;183(1):4-7.
1997: Felicity E B May; Bruce R Westley
Expression of human intestinal trefoil factor in malignant cells and its regulation by oestrogen in breast cancer cells.
The Journal of pathology 1997;182(4):404-13.
1997: S J Clayton; Felicity E B May; Bruce R Westley
Insulin-like growth factors control the regulation of oestrogen and progesterone receptor expression by oestrogens.
Molecular and cellular endocrinology 1997;128(1-2):57-68.
1997: Vladimir Polshakov; M A Williams; AR Gargaro; Thomas A Frenkiel; Bruce R Westley; M P Chadwick; Felicity E B May; James Feeney
High-resolution solution structure of human pNR-2/pS2: a single trefoil motif protein.
Journal of molecular biology 1997;267(2):418-32.
1997: Felicity E B May; Bruce R Westley
Close physical linkage of the genes encoding the pNR-2/pS2 protein and human spasmolytic protein (hSP).
Human genetics 1997;99(3):303-7.
1996: D R Hodgson; Felicity E B May; Bruce R Westley
Involvement of phenylalanine 23 in the binding of IGF-1 to the insulin and type I IGF receptor.
Regulatory peptides 1996;66(3):191-6.
1996: Michael Daws; Bruce R Westley; Felicity E B May
Paradoxical effects of overexpression of the type I insulin-like growth factor (IGF) receptor on the responsiveness of human breast cancer cells to IGFs and estradiol.
Endocrinology 1996;137(4):1177-86.
1996: Bruce R Westley; Felicity E B May
Cathepsin D and breast cancer.
European journal of cancer (Oxford, England : 1990) 1996;32A(1):15-24.
1995: M Carr; Felicity E B May; T W J Lennard; Bruce R Westley
Determination of oestrogen responsiveness of breast cancer by competitive reverse transcription-polymerase chain reaction.
British journal of cancer 1995;72(6):1427-34.
1995: D R Hodgson; Felicity E B May; Bruce R Westley
Mutations at positions 11 and 60 of insulin-like growth factor 1 reveal differences between its interactions with the type I insulin-like-growth-factor receptor and the insulin receptor.
European journal of biochemistry / FEBS 1995;233(1):299-309.
1994: Bruce R Westley; Felicity E B May
Role of insulin-like growth factors in steroid modulated proliferation.
The Journal of steroid biochemistry and molecular biology 1994;51(1-2):1-9.
1994: A J Stewart; Nigel H Piggott; Felicity E B May; Bruce R Westley
Mitogenic activity of procathepsin D purified from conditioned medium of breast-cancer cells by affinity chromatography on pepstatinyl agarose.
International journal of cancer. Journal international du cancer 1994;57(5):715-8.
1993: Felicity E B May; D J Smith; Bruce R Westley
The human cathepsin D-encoding gene is transcribed from an estrogen-regulated and a constitutive start point.
Gene 1993;134(2):277-82.
1993: J A Henry; C Hennessy; D L Levett; T W J Lennard; Bruce R Westley; Felicity E B May
int-2 amplification in breast cancer: association with decreased survival and relationship to amplification of c-erbB-2 and c-myc.
International journal of cancer. Journal international du cancer 1993;53(5):774-80.
1993: R M Healicon; Bruce R Westley; Felicity E B May
Isolation and characterization of an oestrogen-responsive breast-cancer cell line, EFF-3.
International journal of cancer. Journal international du cancer 1993;53(3):388-94.
1993: L R Wiseman; M D Johnson; A E Wakeling; A E Lykkesfeldt; Felicity E B May; Bruce R Westley
Type I IGF receptor and acquired tamoxifen resistance in oestrogen-responsive human breast cancer cells.
European journal of cancer (Oxford, England : 1990) 1993;29A(16):2256-64.
1992: A J Stewart; Bruce R Westley; Felicity E B May
Modulation of the proliferative response of breast cancer cells to growth factors by oestrogen.
British journal of cancer 1992;66(4):640-8.
1992: JD Collier; K Guo; J Mathew; Felicity E B May; M K Bennett; I P Corbett; Margaret F Bassendine; Alastair D Burt
c-erbB-2 oncogene expression in hepatocellular carcinoma and cholangiocarcinoma.
Journal of hepatology 1992;14(2-3):377-80.
1991: J A Henry; M K Bennett; Nigel H Piggott; D L Levett; Felicity E B May; Bruce R Westley
Expression of the pNR-2/pS2 protein in diverse human epithelial tumours.
British journal of cancer 1991;64(4):677-82.
1991: C Hennessy; J A Henry; Felicity E B May; Bruce R Westley; Brian Angus; T W J Lennard
Expression of anti-metastatic gene nm23.
British journal of cancer 1991;63(6):1024.
1991: J A Henry; Nigel H Piggott; U K Mallick; S Nicholson; John R Farndon; Bruce R Westley; Felicity E B May
pNR-2/pS2 immunohistochemical staining in breast cancer: correlation with prognostic factors and endocrine response.
British journal of cancer 1991;63(4):615-22.
1991: C Hennessy; J A Henry; Felicity E B May; B R Westley; Brian Angus; T W J Lennard
Expression of the antimetastatic gene nm23 in human breast cancer: an association with good prognosis.
Journal of the National Cancer Institute 1991;83(4):281-5.
1991: H R Cochrane; Felicity E B May; T Ashcroft; John H Dark
Enteroviruses and idiopathic dilated cardiomyopathy.
The Journal of pathology 1991;163(2):129-31.
1991: Nigel H Piggott; J A Henry; Felicity E B May; Bruce R Westley
Antipeptide antibodies against the pNR-2 oestrogen-regulated protein of human breast cancer cells and detection of pNR-2 expression in normal tissues by immunohistochemistry.
The Journal of pathology 1991;163(2):95-104.
1990: A J Stewart; M D Johnson; Felicity E B May; Bruce R Westley
Role of insulin-like growth factors and the type I insulin-like growth factor receptor in the estrogen-stimulated proliferation of human breast cancer cells.
The Journal of biological chemistry 1990;265(34):21172-8.
1990: I P Corbett; J A Henry; Brian Angus; C J Watchorn; L Wilkinson; C Hennessy; W J Gullick; N L Tuzi; Felicity E B May; Bruce R Westley
NCL-CB11, a new monoclonal antibody recognizing the internal domain of the c-erbB-2 oncogene protein effective for use on formalin-fixed, paraffin-embedded tissue.
The Journal of pathology 1990;161(1):15-25.
1990: J A Henry; A L McCarthy; Brian Angus; Bruce R Westley; Felicity E B May; S Nicholson; J Cairns; Adrian L Harris; Charles H W Horne
Prognostic significance of the estrogen-regulated protein, cathepsin D, in breast cancer. An immunohistochemical study.
Cancer 1990;65(2):265-71.
1990: J A Henry; S Nicholson; C Hennessy; T W J Lennard; Felicity E B May; Bruce R Westley
Expression of the oestrogen regulated pNR-2 mRNA in human breast cancer: relation to oestrogen receptor mRNA levels and response to tamoxifen therapy.
British journal of cancer 1990;61(1):32-8.
1989: Felicity E B May; M D Johnson; L R Wiseman; A E Wakeling; P Kastner; Bruce R Westley
Regulation of progesterone receptor mRNA by oestradiol and antioestrogens in breast cancer cell lines.
Journal of steroid biochemistry 1989;33(6):1035-41.
1989: Felicity E B May; B R Westley
Characterization of sequences related to the mouse mammary tumor virus that are specific to MCF-7 breast cancer cells.
Cancer research 1989;49(14):3879-83.
1989: L R Wiseman; A E Wakeling; Felicity E B May; Bruce R Westley
Effects of the antioestrogen, ICI 164,384, on oestrogen induced RNAs in MCF-7 cells.
Journal of steroid biochemistry 1989;33(1):1-6.
1989: M D Johnson; Bruce R Westley; Felicity E B May
Oestrogenic activity of tamoxifen and its metabolites on gene regulation and cell proliferation in MCF-7 breast cancer cells.
British journal of cancer 1989;59(5):727-38.
1989: Bruce R Westley; F Hölzel; Felicity E B May
Effects of oestrogen and the antioestrogens, tamoxifen and LY117018, on four oestrogen-regulated RNAs in the EFM-19 breast cancer cell line.
Journal of steroid biochemistry 1989;32(3):365-72.
1988: J A Henry; S Nicholson; John R Farndon; Bruce R Westley; Felicity E B May
Measurement of oestrogen receptor mRNA levels in human breast tumours.
British journal of cancer 1988;58(5):600-5.
1988: Felicity E B May; Bruce R Westley
Identification and characterization of estrogen-regulated RNAs in human breast cancer cells.
The Journal of biological chemistry 1988;263(26):12901-8.
1988: G C Franklin; S Chretien; I M Hanson; H Rochefort; Felicity E B May; B R Westley
Expression of human sequences related to those of mouse mammary tumor virus.
Journal of virology 1988;62(4):1203-10.
1987: Felicity E B May; Bruce R Westley
Effects of tamoxifen and 4-hydroxytamoxifen on the pNR-1 and pNR-2 estrogen-regulated RNAs in human breast cancer cells.
The Journal of biological chemistry 1987;262(33):15894-9.