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Olga Mayans

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Jaclyn Bibby; Ronan M Keegan; Olga Mayans; Martyn D Winn; Daniel J Rigden
AMPLE: a cluster-and-truncate approach to solve the crystal structures of small proteins using rapidly computed ab initio models.
Eleonore von Castelmur; Sonia Barbieri; Guy M Benian; Julijus Bogomolovas; Barbara Franke; Peter V Konarev; Siegfried Labeit; Hiroshi Qadota; Klaus Schulten; Johan Strümpfer; Dmitri I Svergun; Olga Mayans
Identification of an N-terminal inhibitory extension as the primary mechanosensory regulator of twitchin kinase.
Marc Bruning; Barbara Franke; Sonja Leopoldseder; Sonia Barbieri; Igor Barsukov; Zöhre Ucurum; Martin Volk; Olga Mayans
The intracellular Ig fold: a robust protein scaffold for the engineering of molecular recognition.

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All Publications

2012: Jaclyn Bibby; Ronan M Keegan; Olga Mayans; Martyn D Winn; Daniel J Rigden
AMPLE: a cluster-and-truncate approach to solve the crystal structures of small proteins using rapidly computed ab initio models.
Acta crystallographica. Section D, Biological crystallography 2012;68(Pt 12):1622-31.
2012: Eleonore von Castelmur; Sonia Barbieri; Guy M Benian; Julijus Bogomolovas; Barbara Franke; Peter V Konarev; Siegfried Labeit; Hiroshi Qadota; Klaus Schulten; Johan Strümpfer; Dmitri I Svergun; Olga Mayans
Identification of an N-terminal inhibitory extension as the primary mechanosensory regulator of twitchin kinase.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(34):13608-13.
2012: Marc Bruning; Barbara Franke; Sonja Leopoldseder; Sonia Barbieri; Igor Barsukov; Zöhre Ucurum; Martin Volk; Olga Mayans
The intracellular Ig fold: a robust protein scaffold for the engineering of molecular recognition.
Protein engineering, design & selection : PEDS 2012;25(5):205-12.
2012: Olga Mayans; Siegfried Labeit
MuRFs: specialized members of the TRIM/RBCC family with roles in the regulation of the trophic state of muscle and its metabolism.
Advances in experimental medicine and biology 2012;770():119-29.
2010: Marc Bruning; Laurent Kreplak; Sonja Leopoldseder; Shirley A Müller; Philippe Ringler; Laurence Duchesne; David G Fernig; Andreas Engel; Zöhre Ucurum-Fotiadis; Olga Mayans
Bipartite design of a self-fibrillating protein copolymer with nanopatterned peptide display capabilities.
Nano letters 2010;10(11):4533-7.
2010: Rainer M Bucher; Dmitri I Svergun; Claudia Muhle-Goll; Olga Mayans
The structure of the FnIII Tandem A77-A78 points to a periodically conserved architecture in the myosin-binding region of titin.
Journal of molecular biology 2010;401(5):843-53.
2010: Eric H Lee; Jen Hsin; Eleonore von Castelmur; Olga Mayans; Klaus Schulten
Tertiary and secondary structure elasticity of a six-Ig titin chain.
Biophysical journal 2010;98(6):1085-95.
2009: Sandra Schlee; Miriam Deuss; Marc Bruning; Andreas Ivens; Thomas Schwab; Nadja Hellmann; Olga Mayans; Reinhard Sterner
Activation of anthranilate phosphoribosyltransferase from Sulfolobus solfataricus by removal of magnesium inhibition and acceleration of product release .
Biochemistry 2009;48(23):5199-209.
2008: Michael Mrosek; Sebastian Meier; Zöhre Ucurum-Fotiadis; Eleonore von Castelmur; Erik Hedbom; Ariel Lustig; Stephan Grzesiek; Dietmar Labeit; Siegfried Labeit; Olga Mayans
Structural analysis of B-Box 2 from MuRF1: identification of a novel self-association pattern in a RING-like fold.
Biochemistry 2008;47(40):10722-30.
2008: Alexandre Urzhumtsev; Eleonore von Castelmur; Olga Mayans
Ultralow-resolution ab initio phasing of filamentous proteins: crystals from a six-Ig fragment of titin as a case study.
Acta crystallographica. Section D, Biological crystallography 2008;64(Pt 5):478-86.
2008: Thomas Schwab; Darko Skegro; Olga Mayans; Reinhard Sterner
A rationally designed monomeric variant of anthranilate phosphoribosyltransferase from Sulfolobus solfataricus is as active as the dimeric wild-type enzyme but less thermostable.
Journal of molecular biology 2008;376(2):506-16.
2008: Eleonore von Castelmur; Marco Marino; Dmitri I Svergun; Laurent Kreplak; Zöhre Ucurum-Fotiadis; Peter V Konarev; Alexandre Urzhumtsev; Dietmar Labeit; Siegfried Labeit; Olga Mayans
A regular pattern of Ig super-motifs defines segmental flexibility as the elastic mechanism of the titin chain.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(4):1186-91.
2007: Eric H Lee; Jen Hsin; Olga Mayans; Klaus Schulten
Secondary and tertiary structure elasticity of titin Z1Z2 and a titin chain model.
Biophysical journal 2007;93(5):1719-35.
2007: Michael Mrosek; Dietmar Labeit; Stephanie Witt; Heiko Heerklotz; Eleonore von Castelmur; Siegfried Labeit; Olga Mayans
Molecular determinants for the recruitment of the ubiquitin-ligase MuRF-1 onto M-line titin.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2007;21(7):1383-92.
2007: Luc Snyers; Sylvia Vlcek; Thomas Dechat; Darko Skegro; Barbara Korbei; Andreas Gajewski; Olga Mayans; Christian Schöfer; Roland Foisner
Lamina-associated polypeptide 2-alpha forms homo-trimers via its C terminus, and oligomerization is unaffected by a disease-causing mutation.
The Journal of biological chemistry 2007;282(9):6308-15.
2006: Marco Marino; Peijian Zou; Dmitri I Svergun; Pilar Garcia; Christian Edlich; Bernd Simon; Matthias Wilmanns; Claudia Muhle-Goll; Olga Mayans
The Ig doublet Z1Z2: a model system for the hybrid analysis of conformational dynamics in Ig tandems from titin.
Structure (London, England : 1993) 2006;14(9):1437-47.
2006: Marco Marino; Miriam Deuss; Dmitri I Svergun; Peter V Konarev; Reinhard Sterner; Olga Mayans
Structural and mutational analysis of substrate complexation by anthranilate phosphoribosyltransferase from Sulfolobus solfataricus.
The Journal of biological chemistry 2006;281(30):21410-21.
2006: Pilar Garcia; Zöhre Ucurum; Rainer Bucher; Dmitri I Svergun; Thomas Huber; Ariel Lustig; Peter V Konarev; Marco Marino; Olga Mayans
Molecular insights into the self-assembly mechanism of dystrophia myotonica kinase.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006;20(8):1142-51.
2006: Peijian Zou; Nikos Pinotsis; Stephan Lange; Young-Hwa Song; Alexander Popov; Irene Mavridis; Olga Mayans; Mathias Gautel; Matthias Wilmanns
Palindromic assembly of the giant muscle protein titin in the sarcomeric Z-disk.
Nature 2006;439(7073):229-33.
2005: Marco Marino; Dmitri I Svergun; Laurent Kreplak; Peter V Konarev; Bohumil Maco; Dietmar Labeit; Olga Mayans
Poly-Ig tandems from I-band titin share extended domain arrangements irrespective of the distinct features of their modular constituents.
Journal of muscle research and cell motility 2005;26(6-8):355-65.
2004: Pilar Garcia; Marco Marino; Olga Mayans
Crystallization and preliminary X-ray analysis of the coiled-coil domain of dystrophia myotonica kinase.
Acta crystallographica. Section D, Biological crystallography 2004;60(Pt 12 Pt 2):2336-9.
2003: Anni Linden; Olga Mayans; Wolfram Meyer-Klaucke; Garabed Antranikian; Matthias Wilmanns
Differential regulation of a hyperthermophilic alpha-amylase with a novel (Ca,Zn) two-metal center by zinc.
The Journal of biological chemistry 2003;278(11):9875-84.
2002: Alice Douangamath; Fabian V Filipp; André T J Klein; Phil Barnett; Peijian Zou; Tineke Voorn-Brouwer; M Cristina Vega; Olga Mayans; Michael Sattler; Ben Distel; Matthias Wilmanns
Topography for independent binding of alpha-helical and PPII-helical ligands to a peroxisomal SH3 domain.
Molecular cell 2002;10(5):1007-17.
2002: Olga Mayans; Andreas Ivens; Johan Nissen; Kasper Kirschner; Matthias Wilmanns
Structural analysis of two enzymes catalysing reverse metabolic reactions implies common ancestry.
The EMBO journal 2002;21(13):3245-54.
2002: Andreas Ivens; Olga Mayans; Halina Szadkowski; Catharina Jürgens; Matthias Wilmanns; Kasper Kirschner
Stabilization of a (betaalpha)8-barrel protein by an engineered disulfide bridge.
European journal of biochemistry / FEBS 2002;269(4):1145-53.
2001: Olga Mayans; J Wuerges; S Canela; Mathias Gautel; Matthias Wilmanns
Structural evidence for a possible role of reversible disulphide bridge formation in the elasticity of the muscle protein titin.
Structure (London, England : 1993) 2001;9(4):331-40.
2001: Andreas Ivens; Olga Mayans; Halina Szadkowski; Matthias Wilmanns; Kasper Kirschner
Purification, characterization and crystallization of thermostable anthranilate phosphoribosyltransferase from Sulfolobus solfataricus.
European journal of biochemistry / FEBS 2001;268(8):2246-52.
2000: M Wilmann; Mathias Gautel; Olga Mayans
Activation of calcium/calmodulin regulated kinases.
Cellular and molecular biology (Noisy-le-Grand, France) 2000;46(5):883-94.
1998: Olga Mayans; Peter F.M. van der Ven; M Wilm; A Mues; P Young; Dieter O Fürst; Matthias Wilmanns; Mathias Gautel
Structural basis for activation of the titin kinase domain during myofibrillogenesis.
Nature 1998;395(6705):863-9.