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Christopher Mayhew

Research Profile

Chemicals & Drugs

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Publications

TOP 3
Li Peng; Christopher N Mayhew; Michael Schnekenburger; Erik S Knudsen; Alvaro Puga
Repression of Ah receptor and induction of transforming growth factor-beta genes in DEN-induced mouse liver tumors.
Michael P Markey; J Bergseid; Emily E Bosco; K Stengel; H Xu; Christopher N Mayhew; Sandy Schwemberger; Wesley A Braden; Y Jiang; George Babcock; anil jegga; Bruce Aronow; Michael F Reed; J Y J Wang; Erik S Knudsen
Loss of the retinoblastoma tumor suppressor: differential action on transcriptional programs related to cell cycle control and immune function.
Christopher N Mayhew; Scott L Carter; Sejal R Fox; Charlene R Sexton; Christopher A Reed; Seetha V Srinivasan; Xiangdong Liu; Kathryn Ann Wikenheiser-Brokamp; Gregory P Boivin; Ju Seog Lee; Bruce Aronow; Snorri S Thorgeirsson; Erik S Knudsen
RB loss abrogates cell cycle control and genome integrity to promote liver tumorigenesis.

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All Publications

2008: Li Peng; Christopher N Mayhew; Michael Schnekenburger; Erik S Knudsen; Alvaro Puga
Repression of Ah receptor and induction of transforming growth factor-beta genes in DEN-induced mouse liver tumors.
Toxicology 2008;246(2-3):242-7.
2007: Michael P Markey; J Bergseid; Emily E Bosco; K Stengel; H Xu; Christopher N Mayhew; Sandy Schwemberger; Wesley A Braden; Y Jiang; George Babcock; anil jegga; Bruce Aronow; Michael F Reed; J Y J Wang; Erik S Knudsen
Loss of the retinoblastoma tumor suppressor: differential action on transcriptional programs related to cell cycle control and immune function.
Oncogene 2007;26(43):6307-18.
2007: Christopher N Mayhew; Scott L Carter; Sejal R Fox; Charlene R Sexton; Christopher A Reed; Seetha V Srinivasan; Xiangdong Liu; Kathryn Ann Wikenheiser-Brokamp; Gregory P Boivin; Ju Seog Lee; Bruce Aronow; Snorri S Thorgeirsson; Erik S Knudsen
RB loss abrogates cell cycle control and genome integrity to promote liver tumorigenesis.
Gastroenterology 2007;133(3):976-84.
2007: Seetha V Srinivasan; Christopher N Mayhew; Sandy Schwemberger; William A Zagorski; Erik S Knudsen
RB loss promotes aberrant ploidy by deregulating levels and activity of DNA replication factors.
The Journal of biological chemistry 2007;282(33):23867-77.
2006: Erik S Knudsen; Charlene R Sexton; Christopher N Mayhew
Role of the retinoblastoma tumor suppressor in the maintenance of genome integrity.
Current molecular medicine 2006;6(7):749-57.
2005: Christopher N Mayhew; Emily E Bosco; Sejal R Fox; Tomohisa Okaya; Pheruza Tarapore; Sandy Schwemberger; George Babcock; Alex B Lentsch; Kenji Fukasawa; Erik S Knudsen
Liver-specific pRB loss results in ectopic cell cycle entry and aberrant ploidy.
Cancer research 2005;65(11):4568-77.
2004: Ranjaka W Gunawardena; Hasan Siddiqui; David A Solomon; Christopher N Mayhew; Justin Held; Steven P. Angus; Erik S Knudsen
Hierarchical requirement of SWI/SNF in retinoblastoma tumor suppressor-mediated repression of Plk1.
The Journal of biological chemistry 2004;279(28):29278-85.
2004: Steven P. Angus; Christopher N Mayhew; David A Solomon; Wesley A Braden; Michael P Markey; Yukiko Okuno; M Cristina Cardoso; David M Gilbert; Erik S Knudsen
RB reversibly inhibits DNA replication via two temporally distinct mechanisms.
Molecular and cellular biology 2004;24(12):5404-20.
2004: Christopher N Mayhew; Lisa M Perkin; Xiaoping Zhang; Julien Sage; Tyler Jacks; Erik S Knudsen
Discrete signaling pathways participate in RB-dependent responses to chemotherapeutic agents.
Oncogene 2004;23(23):4107-20.
2004: John T Powers; SungKi Hong; Christopher N Mayhew; Pamela M Rogers; Erik S Knudsen; David G Johnson
E2F1 uses the ATM signaling pathway to induce p53 and Chk2 phosphorylation and apoptosis.
Molecular cancer research : MCR 2004;2(4):203-14.
2004: Christopher N Mayhew; Emily E Bosco; David A Solomon; Erik S Knudsen; Steven P. Angus
Analysis of RB action in DNA damage checkpoint response.
Methods in molecular biology (Clifton, N.J.) 2004;281():3-16.
2004: Emily E Bosco; Christopher N Mayhew; Robert F Hennigan; Julien Sage; Tyler Jacks; Erik S Knudsen
RB signaling prevents replication-dependent DNA double-strand breaks following genotoxic insult.
Nucleic acids research 2004;32(1):25-34.