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Tadanori Mayumi

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Kohei Yamashita; Yasuo Yoshioka; Kazuma Higashisaka; Kazuya Mimura; Yuki Morishita; Masatoshi Nozaki; Tokuyuki Yoshida; Toshinobu Ogura; Hiromi Nabeshi; Kazuya Nagano; Yasuhiro Abe; Haruhiko Kamada; Youko Monobe; Takayoshi Imazawa; Hisae Aoshima; Kiyoshi Shishido; Yuichi Kawai; Tadanori Mayumi; Shin-Ichi Tsunoda; Norio Itoh; Tomoaki Yoshikawa; Itaru Yanagihara; Shigeru Saito; Yasuo Tsutsumi
Silica and titanium dioxide nanoparticles cause pregnancy complications in mice.
Hiromi Nabeshi; Tomoaki Yoshikawa; Keigo Matsuyama; Yasutaro Nakazato; Kazuhiko Matsuo; Akihiro Arimori; Masaaki Isobe; Saeko Tochigi; Sayuri Kondoh; Toshiro Hirai; Takanori Akase; Takuya Yamashita; Kohei Yamashita; Tokuyuki Yoshida; Kazuya Nagano; Yasuhiro Abe; Yasuo Yoshioka; Haruhiko Kamada; Takayoshi Imazawa; Norio Itoh; Shinsaku Nakagawa; Tadanori Mayumi; Shin-Ichi Tsunoda; Yasuo Tsutsumi
Systemic distribution, nuclear entry and cytotoxicity of amorphous nanosilica following topical application.
Kohei Yamashita; Yasuo Yoshioka; Kazuma Higashisaka; Yuki Morishita; Tokuyuki Yoshida; Maho Fujimura; Hiroyuki Kayamuro; Hiromi Nabeshi; Takuya Yamashita; Kazuya Nagano; Yasuhiro Abe; Haruhiko Kamada; Yuichi Kawai; Tadanori Mayumi; Tomoaki Yoshikawa; Norio Itoh; Shin-ichi Tsunoda; Yasuo Tsutsumi
Carbon nanotubes elicit DNA damage and inflammatory response relative to their size and shape.

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All Publications

2011: Kohei Yamashita; Yasuo Yoshioka; Kazuma Higashisaka; Kazuya Mimura; Yuki Morishita; Masatoshi Nozaki; Tokuyuki Yoshida; Toshinobu Ogura; Hiromi Nabeshi; Kazuya Nagano; Yasuhiro Abe; Haruhiko Kamada; Youko Monobe; Takayoshi Imazawa; Hisae Aoshima; Kiyoshi Shishido; Yuichi Kawai; Tadanori Mayumi; Shin-Ichi Tsunoda; Norio Itoh; Tomoaki Yoshikawa; Itaru Yanagihara; Shigeru Saito; Yasuo Tsutsumi
Silica and titanium dioxide nanoparticles cause pregnancy complications in mice.
Nature nanotechnology 2011;6(5):321-8.
2011: Hiromi Nabeshi; Tomoaki Yoshikawa; Keigo Matsuyama; Yasutaro Nakazato; Kazuhiko Matsuo; Akihiro Arimori; Masaaki Isobe; Saeko Tochigi; Sayuri Kondoh; Toshiro Hirai; Takanori Akase; Takuya Yamashita; Kohei Yamashita; Tokuyuki Yoshida; Kazuya Nagano; Yasuhiro Abe; Yasuo Yoshioka; Haruhiko Kamada; Takayoshi Imazawa; Norio Itoh; Shinsaku Nakagawa; Tadanori Mayumi; Shin-Ichi Tsunoda; Yasuo Tsutsumi
Systemic distribution, nuclear entry and cytotoxicity of amorphous nanosilica following topical application.
Biomaterials 2011;32(11):2713-24.
2010: Kohei Yamashita; Yasuo Yoshioka; Kazuma Higashisaka; Yuki Morishita; Tokuyuki Yoshida; Maho Fujimura; Hiroyuki Kayamuro; Hiromi Nabeshi; Takuya Yamashita; Kazuya Nagano; Yasuhiro Abe; Haruhiko Kamada; Yuichi Kawai; Tadanori Mayumi; Tomoaki Yoshikawa; Norio Itoh; Shin-ichi Tsunoda; Yasuo Tsutsumi
Carbon nanotubes elicit DNA damage and inflammatory response relative to their size and shape.
Inflammation 2010;33(4):276-80.
2010: H Kayamuro; Yasuhiro Abe; Yasuo Yoshioka; Kazufumi Katayama; T Yoshida; K Yamashita; Tomoaki Yoshikawa; Y Kawai; Tadanori Mayumi; Takachika Hiroi; Norio Itoh; Kazuya Nagano; Haruhiko Kamada; Shin-ichi Tsunoda; Yasuo Tsutsumi
Mutant TNF-alpha, mTNF-K90R, is a novel candidate adjuvant for a mucosal vaccine against HIV.
Die Pharmazie 2010;65(4):254-6.
2010: Tokuyuki Yoshida; Yasuo Yoshioka; Maho Fujimura; Hiroyuki Kayamuro; Kohei Yamashita; Kazuma Higashisaka; Ryosuke Nakanishi; Yuki Morishita; Hiromi Nabeshi; Takuya Yamashita; Masashi Muroi; Kenichi Tanamoto; Kazuya Nagano; Yasuhiro Abe; Haruhiko Kamada; Yuichi Kawai; Tadanori Mayumi; Norio Itoh; Tomoaki Yoshikawa; Shinichi Tsunoda; Yasuo Tsutsumi
Urban aerosols induce pro-inflammatory cytokine production in macrophages and cause airway inflammation in vivo.
Biological & pharmaceutical bulletin 2010;33(5):780-3.
2009: Hiroyuki Kayamuro; Yasuhiro Abe; Yasuo Yoshioka; Kazufumi Katayama; Tetsuya Nomura; Tokuyuki Yoshida; Kohei Yamashita; Tomoaki Yoshikawa; Yuichi Kawai; Tadanori Mayumi; Takachika Hiroi; Norio Itoh; Kazuya Nagano; Haruhiko Kamada; Shin-ichi Tsunoda; Yasuo Tsutsumi
The use of a mutant TNF-alpha as a vaccine adjuvant for the induction of mucosal immune responses.
Biomaterials 2009;30(29):5869-76.
2009: Hiroyuki Kayamuro; Yasuo Yoshioka; Yasuhiro Abe; Kazufumi Katayama; T Yoshida; Kohei Yamashita; Tomoaki Yoshikawa; Takachika Hiroi; Norio Itoh; Yuichi Kawai; Tadanori Mayumi; Haruhiko Kamada; Shin-ichi Tsunoda; Yasuo Tsutsumi
TNF superfamily member, TL1A, is a potential mucosal vaccine adjuvant.
Biochemical and biophysical research communications 2009;384(3):296-300.
2009: Jian-Qing Gao; Yasuhiro Tsuda; Min Han; Dong-Hang Xu; Naoko Kanagawa; Yutaka Hatanaka; Yoichi Tani; Hiroyuki Mizuguchi; Yasuo Tsutsumi; Tadanori Mayumi; Naoki Okada; Shinsaku Nakagawa
NK cells are migrated and indispensable in the anti-tumor activity induced by CCL27 gene therapy.
Cancer immunology, immunotherapy : CII 2009;58(2):291-9.
2008: Hiroko Shibata; Yasuo Yoshioka; Akiko Ohkawa; Yasuhiro Abe; Tetsuya Nomura; Yohei Mukai; Shinsaku Nakagawa; Madoka Taniai; Tsunetaka Ohta; Tadanori Mayumi; Haruhiko Kamada; Shin-ichi Tsunoda; Yasuo Tsutsumi
The therapeutic effect of TNFR1-selective antagonistic mutant TNF-alpha in murine hepatitis models.
Cytokine 2008;44(2):229-33.
2008: Jian-Qing Gao; Naoko Kanagawa; Dong-Hang Xu; Min Han; Toshiki Sugita; Yutaka Hatanaka; Yoichi Tani; Hiroyuki Mizuguchi; Yasuo Tsutsumi; Tadanori Mayumi; Naoki Okada; Shinsaku Nakagawa
Combination of two fiber-mutant adenovirus vectors, one encoding the chemokine FKN and another encoding cytokine interleukin 12, elicits notably enhanced anti-tumor responses.
Cancer immunology, immunotherapy : CII 2008;57(11):1657-64.
2008: Min Han; Jin-Liang Chen; Ying Hu; Cai-Li He; Wu-Ping Shuai; Jian-Heng Yu; Hai-Liang Chen; Wen-Quan Liang; Tadanori Mayumi; Nakagawa Shinsaku; Jian-Qing Gao
In vitro and in vivo tumor suppressive activity induced by human telomerase transcriptase-targeting antisense oligonucleotides mediated by cationic liposomes.
Journal of bioscience and bioengineering 2008;106(3):243-7.
2008: Jian-Qing Gao; Naoki Okada; Tadanori Mayumi; Shinsaku Nakagawa
Immune cell recruitment and cell-based system for cancer therapy.
Pharmaceutical research 2008;25(4):752-68.
2008: Hiroko Shibata; Yasuo Yoshioka; Akiko Ohkawa; Kyoko Minowa; Yohei Mukai; Yasuhiro Abe; Madoka Taniai; Tetsuya Nomura; Hiroyuki Kayamuro; Hiromi Nabeshi; Toshiki Sugita; Sunao Imai; Kazuya Nagano; Tomoaki Yoshikawa; Takuya Fujita; Shinsaku Nakagawa; Akira Yamamoto; Tsunetaka Ohta; Takao Hayakawa; Tadanori Mayumi; Peter Vandenabeele; Bharat B Aggarwal; Teruya Nakamura; Yuriko Yamagata; Shin-ichi Tsunoda; Haruhiko Kamada; Yasuo Tsutsumi
Creation and X-ray structure analysis of the tumor necrosis factor receptor-1-selective mutant of a tumor necrosis factor-alpha antagonist.
The Journal of biological chemistry 2008;283(2):998-1007.
2007: Jian-Qing Gao; Yusuke Eto; Yasuo Yoshioka; Fumiko Sekiguchi; Shinnosuke Kurachi; Tomohiro Morishige; Xinglei Yao; Hikaru Watanabe; Ratima Asavatanabodee; Fuminori Sakurai; Hiroyuki Mizuguchi; Yuka Okada; Yohei Mukai; Yasuo Tsutsumi; Tadanori Mayumi; Naoki Okada; Shinsaku Nakagawa
Effective tumor targeted gene transfer using PEGylated adenovirus vector via systemic administration.
Journal of controlled release : official journal of the Controlled Release Society 2007;122(1):102-10.
2007: Hiroko Shibata; Haruhiko Kamada; Kyoko Kobayashi-Nishibata; Yasuo Yoshioka; Toshihide Nishibata; Yasuhiro Abe; Tetsuya Nomura; Hiromi Nabeshi; Kyoko Minowa; Yohei Mukai; Shinsaku Nakagawa; Tadanori Mayumi; Shin-Ichi Tsunoda; Yasuo Tsutsumi
Role of amino acid residue 90 in bioactivity and receptor binding capacity of tumor necrosis factor mutants.
Biochimica et biophysica acta 2007;1774(8):1029-35.
2007: Jian-Qing Gao; Naoko Kanagawa; Y Motomura; T Yanagawa; Toshiki Sugita; Yutaka Hatanaka; Yoichi Tani; Hiroyuki Mizuguchi; Yasuo Tsutsumi; Tadanori Mayumi; Naoki Okada; Shinsaku Nakagawa
Cotransduction of CCL27 gene can improve the efficacy and safety of IL-12 gene therapy for cancer.
Gene therapy 2007;14(6):491-502.
2007: Akira Hayashi; Hisashi Wakita; Tomoaki Yoshikawa; Tsuyoshi Nakanishi; Yasuo Tsutsumi; Tadanori Mayumi; Yohei Mukai; Yasuo Yoshioka; Naoki Okada; Shinsaku Nakagawa
A strategy for efficient cross-presentation of CTL-epitope peptides leading to enhanced induction of in vivo tumor immunity.
Journal of controlled release : official journal of the Controlled Release Society 2007;117(1):11-9.
2006: Koichiro Wada; Atsushi Nakajima; Kazufumi Katayama; Chiho Kudo; Atsuhito Shibuya; Naoto Kubota; Yasuo Terauchi; Masashi Tachibana; Hiroyuki Miyoshi; Yoshinori Kamisaki; Tadanori Mayumi; Takashi Kadowaki; Richard S Blumberg
Peroxisome proliferator-activated receptor gamma-mediated regulation of neural stem cell proliferation and differentiation.
The Journal of biological chemistry 2006;281(18):12673-81.
2006: Shunji Aoki; Seok-hwan Cho; Mayumi Ono; Takashi Kuwano; Shintaro Nakao; Michihiko Kuwano; Shinsaku Nakagawa; Jian-Qing Gao; Tadanori Mayumi; Masabumi Shibuya; Motomasa Kobayashi
Bastadin 6, a spongean brominated tyrosine derivative, inhibits tumor angiogenesis by inducing selective apoptosis to endothelial cells.
Anti-cancer drugs 2006;17(3):269-78.
2006: Shinya Kida; Mitsuko Maeda; Keiko Hojo; Yusuke Eto; Jian-Qing Gao; Shinnosuke Kurachi; Hiroyuki Mizuguchi; Takao Hayakawa; Tadanori Mayumi; Shinsaku Nakagawa; Koichi Kawasaki
Design and synthesis of a Tat-related gene transporter: a tool for carrying the adenovirus vector into cells.
Bioorganic & medicinal chemistry letters 2006;16(3):743-5.
2006: Tomoaki Yoshikawa; Susumu Imazu; Jian-Qing Gao; Kazuyuki Hayashi; Yasuhiro Tsuda; Naoki Okada; Yasuo Tsutsumi; Mitsuru Akashi; Tadanori Mayumi; Shinsaku Nakagawa
Non-methylated CpG motif packaged into fusogenic liposomes enhance antigen-specific immunity in mice.
Biological & pharmaceutical bulletin 2006;29(1):105-9.
2006: Tomoaki Yoshikawa; Naoki Okada; Masaki Tsujino; Jian-Qing Gao; Akira Hayashi; Yasuo Tsutsumi; Tadanori Mayumi; Akira Yamamoto; Shinsaku Nakagawa
Vaccine efficacy of fusogenic liposomes containing tumor cell-lysate against murine B16BL6 melanoma.
Biological & pharmaceutical bulletin 2006;29(1):100-4.
2005: Jun Kunisawa; Takashi Masuda; Kazufumi Katayama; Tomoaki Yoshikawa; Yasuo Tsutsumi; Mitsuru Akashi; Tadanori Mayumi; Shinsaku Nakagawa
Fusogenic liposome delivers encapsulated nanoparticles for cytosolic controlled gene release.
Journal of controlled release : official journal of the Controlled Release Society 2005;105(3):344-53.
2005: Yuka Okada; Naoki Okada; Hiroyuki Mizuguchi; Takao Hayakawa; Shinsaku Nakagawa; Tadanori Mayumi
Transcriptional targeting of RGD fiber-mutant adenovirus vectors can improve the safety of suicide gene therapy for murine melanoma.
Cancer gene therapy 2005;12(7):608-16.
2005: Jian-Qing Gao; Toshiki Sugita; Naoko Kanagawa; Keisuke Iida; Naoki Okada; Hiroyuki Mizuguchi; Takashi Nakayama; Takao Hayakawa; Osamu Yoshie; Yasuo Tsutsumi; Tadanori Mayumi; Shinsaku Nakagawa
Anti-tumor responses induced by chemokine CCL19 transfected into an ovarian carcinoma model via fiber-mutant adenovirus vector.
Biological & pharmaceutical bulletin 2005;28(6):1066-70.
2005: Yusuke Eto; Jian-Qing Gao; Fumiko Sekiguchi; Shinnosuke Kurachi; Kazufumi Katayama; Mitsuko Maeda; Koichi Kawasaki; Hiroyuki Mizuguchi; Takao Hayakawa; Yasuo Tsutsumi; Tadanori Mayumi; Shinsaku Nakagawa
PEGylated adenovirus vectors containing RGD peptides on the tip of PEG show high transduction efficiency and antibody evasion ability.
The journal of gene medicine 2005;7(5):604-12.
2005: Tetsuji Hosono; Hiroyuki Mizuguchi; Kazufumi Katayama; Naoya Koizumi; Kenji Kawabata; Teruhide Yamaguchi; Shinsaku Nakagawa; Yoshiteru Watanabe; Tadanori Mayumi; Takao Hayakawa
RNA interference of PPARgamma using fiber-modified adenovirus vector efficiently suppresses preadipocyte-to-adipocyte differentiation in 3T3-L1 cells.
Gene 2005;348():157-65.
2005: Jian-Qing Gao; Toshiki Sugita; Naoko Kanagawa; Keisuke Iida; Yusuke Eto; Yoshiaki Motomura; Hiroyuki Mizuguchi; Yasuo Tsutsumi; Takao Hayakawa; Tadanori Mayumi; Shinsaku Nakagawa
A single intratumoral injection of a fiber-mutant adenoviral vector encoding interleukin 12 induces remarkable anti-tumor and anti-metastatic activity in mice with Meth-A fibrosarcoma.
Biochemical and biophysical research communications 2005;328(4):1043-50.
2005: Kazufumi Katayama; Koichiro Wada; Atsushi Nakajima; Yoshinori Kamisaki; Tadanori Mayumi
Nuclear receptors as targets for drug development: the role of nuclear receptors during neural stem cell proliferation and differentiation.
Journal of pharmacological sciences 2005;97(2):171-6.
2005: Mitsuko Maeda; Shinya Kida; Keiko Hojo; Yusuke Eto; Jian-Qing Gaob; Shinnosuke Kurachi; Fumiko Sekiguchi; Hiroyuki Mizuguchi; Takao Hayakawa; Tadanori Mayumi; Shinsaku Nakagawa; Koichi Kawasaki
Design and synthesis of a peptide-PEG transporter tool for carrying adenovirus vector into cells.
Bioorganic & medicinal chemistry letters 2005;15(3):621-4.
2005: Toshiki Sugita; Tomoaki Yoshikawa; Jian-Qing Gao; Mariko Shimokawa; Atushi Oda; Takako Niwa; Mitsuru Akashi; Yasuo Tsutsumi; Tadanori Mayumi; Shinsaku Nakagawa
Fusogenic liposome can be used as an effective vaccine carrier for peptide vaccination to induce cytotoxic T lymphocyte (CTL) response.
Biological & pharmaceutical bulletin 2005;28(1):192-3.
2004: Hiroko Shibata; Yasuo Yoshioka; Shinji Ikemizu; Kyoko Kobayashi; Yoko Yamamoto; Yohei Mukai; Takayuki Okamoto; Madoka Taniai; Maki Kawamura; Yasuhiro Abe; Shinsaku Nakagawa; Takao Hayakawa; Satoshi Nagata; Yuriko Yamagata; Tadanori Mayumi; Haruhiko Kamada; Yasuo Tsutsumi
Functionalization of tumor necrosis factor-alpha using phage display technique and PEGylation improves its antitumor therapeutic window.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(24):8293-300.
2004: Tomoaki Yoshikawa; Susumu Imazu; Jian-Qing Gao; Kazuyuki Hayashi; Yasuhiro Tsuda; Mariko Shimokawa; Toshiki Sugita; Takako Niwa; Atushi Oda; Mitsuru Akashi; Yasuo Tsutsumi; Tadanori Mayumi; Shinsaku Nakagawa
Augmentation of antigen-specific immune responses using DNA-fusogenic liposome vaccine.
Biochemical and biophysical research communications 2004;325(2):500-5.
2004: Takayuki Okamoto; Yohei Mukai; Yasuo Yoshioka; Hiroko Shibata; Maki Kawamura; Yoko Yamamoto; Shinsaku Nakagawa; Haruhiko Kamada; Takao Hayakawa; Tadanori Mayumi; Yasuo Tsutsumi
Optimal construction of non-immune scFv phage display libraries from mouse bone marrow and spleen established to select specific scFvs efficiently binding to antigen.
Biochemical and biophysical research communications 2004;323(2):583-91.
2004: Hiroko Shibata; Shinsaku Nakagawa; Tadanori Mayumi; Yasuo Tsutsumi
Development of novel drug delivery system (DDS) technologies for proteomic-based drug development.
Biological & pharmaceutical bulletin 2004;27(10):1483-8.
2004: Tetsuji Hosono; Hiroyuki Mizuguchi; Kazufumi Katayama; Zhi-Li Xu; Fuminori Sakurai; Akiko Ishii-Watabe; Kenji Kawabata; Teruhide Yamaguchi; Shinsaku Nakagawa; Tadanori Mayumi; Takao Hayakawa
Adenovirus vector-mediated doxycycline-inducible RNA interference.
Human gene therapy 2004;15(8):813-9.
2004: Yasuo Yoshioka; Yasuo Tsutsumi; Yohei Mukai; Hiroko Shibata; Takayuki Okamoto; Yoshihisa Kaneda; Shin-ichi Tsunoda; Haruhiko Kamada; Keiichi Koizumi; Yoko Yamamoto; Yu Mu; Hiroshi Kodaira; Keiko Sato-Kamada; Shinsaku Nakagawa; Tadanori Mayumi
Effective accumulation of poly(vinylpyrrolidone-co-vinyl laurate) into the spleen.
Journal of biomedical materials research. Part A 2004;70(2):219-23.
2004: Hiroshi Kodaira; Yasuo Tsutsumi; Yasuo Yoshioka; Haruhiko Kamada; Yoshihisa Kaneda; Yoko Yamamoto; Shin-ichi Tsunoda; Takayuki Okamoto; Yohei Mukai; Hiroko Shibata; Shinsaku Nakagawa; Tadanori Mayumi
The targeting of anionized polyvinylpyrrolidone to the renal system.
Biomaterials 2004;25(18):4309-15.
2004: Yasuo Yoshioka; Yasuo Tsutsumi; Shinsaku Nakagawa; Tadanori Mayumi
Recent progress on tumor missile therapy and tumor vascular targeting therapy as a new approach.
Current vascular pharmacology 2004;2(3):259-70.
2004: Jian-Qing Gao; S Inoue; Y Tsukada; Kazufumi Katayama; Yusuke Eto; Shinnosuke Kurachi; Hiroyuki Mizuguchi; Takao Hayakawa; Yasuo Tsutsumi; Tadanori Mayumi; Shinsaku Nakagawa
High gene expression of the mutant adenovirus vector, both in vitro and in vivo, with the insertion of integrin-targeting peptide into the fiber.
Die Pharmazie 2004;59(7):571-2.
2004: Tadanori Mayumi
[DDS and Me].
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 2004;124(7):397-415.
2004: Yoshihisa Kaneda; Yasuo Tsutsumi; Yasuo Yoshioka; Haruhiko Kamada; Yoko Yamamoto; Hiroshi Kodaira; Shin-ichi Tsunoda; Takayuki Okamoto; Yohei Mukai; Hiroko Shibata; Shinsaku Nakagawa; Tadanori Mayumi
The use of PVP as a polymeric carrier to improve the plasma half-life of drugs.
Biomaterials 2004;25(16):3259-66.
2004: Yusuke Eto; Jian-Qing Gao; Fumiko Sekiguchi; Shinnosuke Kurachi; Kazufumi Katayama; Hiroyuki Mizuguchi; Takao Hayakawa; Yasuo Tsutsumi; Tadanori Mayumi; Shinsaku Nakagawa
Neutralizing antibody evasion ability of adenovirus vector induced by the bioconjugation of methoxypolyethylene glycol succinimidyl propionate (MPEG-SPA).
Biological & pharmaceutical bulletin 2004;27(6):936-8.
2004: Haruhiko Kamada; Yasuo Tsutsumi; Yasuo Yoshioka; Yoko Yamamoto; Hiroshi Kodaira; Shin-ichi Tsunoda; Takayuki Okamoto; Yohei Mukai; Hiroko Shibata; Shinsaku Nakagawa; Tadanori Mayumi
Design of a pH-sensitive polymeric carrier for drug release and its application in cancer therapy.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(7):2545-50.
2004: Yasuo Yoshioka; Yasuo Tsutsumi; Shinji Ikemizu; Yoko Yamamoto; Hiroko Shibata; Toshihide Nishibata; Yohei Mukai; Takayuki Okamoto; Madoka Taniai; Maki Kawamura; Yasuhiro Abe; Shinsaku Nakagawa; Satoshi Nagata; Yuriko Yamagata; Tadanori Mayumi
Optimal site-specific PEGylation of mutant TNF-alpha improves its antitumor potency.
Biochemical and biophysical research communications 2004;315(4):808-14.
2004: Yoko Yamamoto; Yasuo Tsutsumi; Yasuo Yoshioka; Haruhiko Kamada; Keiko Sato-Kamada; Takayuki Okamoto; Yohei Mukai; Hiroko Shibata; Shinsaku Nakagawa; Tadanori Mayumi
Poly(vinylpyrrolidone-co-dimethyl maleic acid) as a novel renal targeting carrier.
Journal of controlled release : official journal of the Controlled Release Society 2004;95(2):229-37.
2004: Jian-Qing Gao; L S Alexandre; Yasuhiro Tsuda; Kazufumi Katayama; Yusuke Eto; Fumiko Sekiguchi; Hiroyuki Mizuguchi; Takao Hayakawa; Takashi Nakayama; Osamu Yoshie; Yasuo Tsutsumi; Tadanori Mayumi; Shinsaku Nakagawa
Tumor-suppressive activities by chemokines introduced into OV-HM cells using fiber-mutant adenovirus vectors.
Die Pharmazie 2004;59(3):238-9.
2004: Yasuo Yoshioka; Yasuo Tsutsumi; Haruhiko Kamada; Tetsuya Kihira; Shin-ichi Tsunoda; Yoko Yamamoto; Takayuki Okamoto; Hiroko Shibata; Yohei Mukai; Madoka Taniai; Tomoe Shimizu; Maki Kawamura; Yasuhiro Abe; Shinsaku Nakagawa; Tadanori Mayumi
Selective enhancer of tumor vascular permeability for optimization of cancer chemotherapy.
Biological & pharmaceutical bulletin 2004;27(3):437-9.
2004: Kazufumi Katayama; Koichiro Wada; Hiroyuki Miyoshi; Kozo Ohashi; Masashi Tachibana; Rie Furuki; Hiroyuki Mizuguchi; Takao Hayakawa; Atsushi Nakajima; Takashi Kadowaki; Yasuo Tsutsumi; Shinsaku Nakagawa; Yoshinori Kamisaki; Tadanori Mayumi
RNA interfering approach for clarifying the PPARgamma pathway using lentiviral vector expressing short hairpin RNA.
FEBS letters 2004;560(1-3):178-82.
2003: Yasuo Yoshioka; Ryo Suzuki; Takayuki Okamoto; Naoki Okada; Yohei Mukai; Hiroko Shibata; Yasuo Tsutsumi; Natsuki Dohi; Noriko Okada; Shinsaku Nakagawa; Tadanori Mayumi
Combination effects of complement regulatory proteins and anti-complement polymer.
Biochimica et biophysica acta 2003;1624(1-3):54-9.
2003: Hiroyuki Mizuguchi; Zhi-Li Xu; Fuminori Sakurai; Tadanori Mayumi; Takao Hayakawa
Tight positive regulation of transgene expression by a single adenovirus vector containing the rtTA and tTS expression cassettes in separate genome regions.
Human gene therapy 2003;14(13):1265-77.
2003: Keiichi Koizumi; Yasuo Tsutsumi; Yasuo Yoshioka; Masaki Watanabe; Takayuki Okamoto; Yohei Mukai; Shinsaku Nakagawa; Tadanori Mayumi
Anti-angiogenic effects of dimethyl sulfoxide on endothelial cells.
Biological & pharmaceutical bulletin 2003;26(9):1295-8.
2003: Jian-Qing Gao; Yasuhiro Tsuda; Kazufumi Katayama; Takashi Nakayama; Yutaka Hatanaka; Yoichi Tani; Hiroyuki Mizuguchi; Takao Hayakawa; Osamu Yoshie; Yasuo Tsutsumi; Tadanori Mayumi; Shinsaku Nakagawa
Antitumor effect by interleukin-11 receptor alpha-locus chemokine/CCL27, introduced into tumor cells through a recombinant adenovirus vector.
Cancer research 2003;63(15):4420-5.
2003: Keiichi Koizumi; Yasuo Tsutsumi; Haruhiko Kamada; Yasuo Yoshioka; Masaki Watanabe; Yoko Yamamoto; Takayuki Okamoto; Yohei Mukai; Shinsaku Nakagawa; Yoichi Tani; Tadanori Mayumi
Incorporation of adult organ-derived endothelial cells into tumor blood vessel.
Biochemical and biophysical research communications 2003;306(1):219-24.
2003: Zhi-Li Xu; Hiroyuki Mizuguchi; Tadanori Mayumi; Takao Hayakawa
Woodchuck hepatitis virus post-transcriptional regulation element enhances transgene expression from adenovirus vectors.
Biochimica et biophysica acta 2003;1621(3):266-71.
2003: Yasuo Yoshioka; Ryo Suzuki; Hiroaki Oka; Naoki Okada; Takayuki Okamoto; Tatsunobu Yoshioka; Yohei Mukai; Hiroko Shibata; Yasuo Tsutsumi; Shinsaku Nakagawa; Jun-ichi Miyazaki; Tadanori Mayumi
A novel cytomedical vehicle capable of protecting cells against complement.
Biochemical and biophysical research communications 2003;305(2):353-8.
2003: Zhi-Li Xu; Hiroyuki Mizuguchi; Tadanori Mayumi; Takao Hayakawa
Regulated gene expression from adenovirus vectors: a systematic comparison of various inducible systems.
Gene 2003;309(2):145-51.
2003: Kazufumi Katayama; Koichiro Wada; Atsushi Nakajima; Hiroyuki Mizuguchi; Takao Hayakawa; Shinsaku Nakagawa; Takashi Kadowaki; Ryozo Nagai; Yoshinori Kamisaki; Richard S Blumberg; Tadanori Mayumi
A novel PPAR gamma gene therapy to control inflammation associated with inflammatory bowel disease in a murine model.
Gastroenterology 2003;124(5):1315-24.
2003: Yoko Yamamoto; Yasuo Tsutsumi; Yasuo Yoshioka; Toshihide Nishibata; Kyoko Kobayashi; Takayuki Okamoto; Yohei Mukai; Tomoe Shimizu; Shinsaku Nakagawa; Satoshi Nagata; Tadanori Mayumi
Site-specific PEGylation of a lysine-deficient TNF-alpha with full bioactivity.
Nature biotechnology 2003;21(5):546-52.
2003: Haruhiko Kamada; Yasuo Tsutsumi; Keiko Sato-Kamada; Yoko Yamamoto; Yasuo Yoshioka; Takayuki Okamoto; Shinsaku Nakagawa; Satoshi Nagata; Tadanori Mayumi
Synthesis of a poly(vinylpyrrolidone-co-dimethyl maleic anhydride) co-polymer and its application for renal drug targeting.
Nature biotechnology 2003;21(4):399-404.
2003: Risako Nakano; Tetsuhiko Nakagawa; Susumu Imazu; Kazufumi Katayama; Hiroyuki Mizuguchi; Takao Hayakawa; Yasuo Tsutsumi; Shinsaku Nakagawa; Tadanori Mayumi
A novel T7 system utilizing mRNA coding for T7 RNA polymerase.
Biochemical and biophysical research communications 2003;301(4):974-8.
2003: Shinsaku Nakagawa; Tadanori Mayumi
Development of novel technology of DDS for gene therapy.
Drug metabolism and pharmacokinetics 2003;18(4):223-9.
2002: Yuichi Susuki; Keiko Hojo; Ikuko Okazaki; Haruhiko Kamata; Masahiko Sasaki; Mitsuko Maeda; Motoyoshi Nomizu; Yoko Yamamoto; Shinsaku Nakagawa; Tadanori Mayumi; Koichi Kawasaki
Preparation and biological activities of a bivalent poly(ethylene glycol) hybrid containing an active site and its synergistic site of fibronectin.
Chemical & pharmaceutical bulletin 2002;50(9):1229-32.
2002: Ryo Suzuki; Naoki Okada; Hajime Miyamoto; Tatsunobu Yoshioka; Kayoko Sakamoto; Hiroaki Oka; Yasuo Tsutsumi; Shinsaku Nakagawa; Jun-ichi Miyazaki; Tadanori Mayumi
Cyotomedical therapy for insulinopenic diabetes using microencapsulated pancreatic beta cell lines.
Life sciences 2002;71(15):1717-29.
2002: Atsuhito Shibuya; Koichiro Wada; Atsushi Nakajima; Makio Saeki; Kazufumi Katayama; Tadanori Mayumi; Takashi Kadowaki; Hitoshi Niwa; Yoshinori Kamisaki
Nitration of PPARgamma inhibits ligand-dependent translocation into the nucleus in a macrophage-like cell line, RAW 264.
FEBS letters 2002;525(1-3):43-7.
2002: Jun Kunisawa; Ichiro Takahashi; Akiko Okudaira; Takachika Hiroi; Kazufumi Katayama; Teruko Ariyama; Yasuo Tsutsumi; Shinsaku Nakagawa; Hiroshi Kiyono; Tadanori Mayumi
Lack of antigen-specific immune responses in anti-IL-7 receptor alpha chain antibody-treated Peyer's patch-null mice following intestinal immunization with microencapsulated antigen.
European journal of immunology 2002;32(8):2347-55.
2002: Tomoko Shiojiri; Koichiro Wada; Atsushi Nakajima; Kazufumi Katayama; Atsuhito Shibuya; Chiho Kudo; Takashi Kadowaki; Tadanori Mayumi; Yoshiaki Yura; Yoshinori Kamisaki
PPAR gamma ligands inhibit nitrotyrosine formation and inflammatory mediator expressions in adjuvant-induced rheumatoid arthritis mice.
European journal of pharmacology 2002;448(2-3):231-8.
2002: Zhi-Li Xu; Hiroyuki Mizuguchi; Akiko Ishii-Watabe; Eriko Uchida; Tadanori Mayumi; Takao Hayakawa
Strength evaluation of transcriptional regulatory elements for transgene expression by adenovirus vector.
Journal of controlled release : official journal of the Controlled Release Society 2002;81(1-2):155-63.
2002: Yoko Yamamoto; Yasuo Tsutsumi; Tadanori Mayumi
Molecular design of bioconjugated cell adhesion peptide with a water-soluble polymeric modifier for enhancement of antimetastatic effect.
Current drug targets 2002;3(2):123-30.
2002: Ryo Suzuki; Yasuo Yoshioka; Etsuko Kitano; Tatsunobu Yoshioka; Hiroaki Oka; Takayuki Okamoto; Naoki Okada; Yasuo Tsutsumi; Shinsaku Nakagawa; Jun-ichi Miyazaki; Hajime Kitamura; Tadanori Mayumi
Development of a novel cytomedical treatment that can protect entrapped cells from host humoral immunity.
Cell transplantation 2002;11(8):787-97.
2001: Jun Kunisawa; Shinsaku Nakagawa; Tadanori Mayumi
Pharmacotherapy by intracellular delivery of drugs using fusogenic liposomes: application to vaccine development.
Advanced drug delivery reviews 2001;52(3):177-86.
2001: Jun Kunisawa; Tsuyoshi Nakanishi; Ichiro Takahashi; Akiko Okudaira; Yasuo Tsutsumi; Kazufumi Katayama; Shinsaku Nakagawa; Hiroshi Kiyono; Tadanori Mayumi
Sendai virus fusion protein mediates simultaneous induction of MHC class I/II-dependent mucosal and systemic immune responses via the nasopharyngeal-associated lymphoreticular tissue immune system.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(3):1406-12.
2001: Zhi-Li Xu; Hiroyuki Mizuguchi; Akiko Ishii-Watabe; Eriko Uchida; Tadanori Mayumi; Takao Hayakawa
Optimization of transcriptional regulatory elements for constructing plasmid vectors.
Gene 2001;272(1-2):149-56.
2001: Keiko Hojo; Yuichi Susuki; Mitsuko Maeda; I Okazaki; Motoyoshi Nomizu; H Kamada; Yoko Yamamoto; Shinsaku Nakagawa; Tadanori Mayumi; Koichi Kawasaki
Amino acids and peptides. Part 39: a bivalent poly(ethylene glycol) hybrid containing an active site (RGD) and its synergistic site (PHSRN) of fibronectin.
Bioorganic & medicinal chemistry letters 2001;11(11):1429-32.
2001: Mitsuko Maeda; H Kamada; Keiko Hojo; Yoko Yamamoto; Shinsaku Nakagawa; Timothy J Smith; Tadanori Mayumi; K Kawasa
Amino acids and peptides. XXXVIII. Facile synthesis of laminin-related peptide-poly(ethylene glycol) hybrids by the solid phase method.
Chemical & pharmaceutical bulletin 2001;49(4):488-91.
2001: Shin-ichi Tsunoda; T Ishikawa; M Watanabe; Haruhiko Kamada; Yoko Yamamoto; Yasuo Tsutsumi; Toshio Hirano; Tadanori Mayumi
Selective enhancement of thrombopoietic activity of PEGylated interleukin 6 by a simple procedure using a reversible amino-protective reagent.
British journal of haematology 2001;112(1):181-8.
2000: Y Wakai; J Matsui; Keiichi Koizumi; Shin-ichi Tsunoda; H Makimoto; Iwao Ohizumi; Kenji Taniguchi; Shin-ichi Kaiho; Hiroshi Saito; Naoki Utoguchi; Yasuo Tsutsumi; Shinsaku Nakagawa; Yoshiyuki Ohsugi; Tadanori Mayumi
Effective cancer targeting using an anti-tumor tissue vascular endothelium-specific monoclonal antibody (TES-23).
Japanese journal of cancer research : Gann 2000;91(12):1319-25.
2000: Haruhiko Kamada; Yasuo Tsutsumi; Yoko Yamamoto; Tetsuya Kihira; Yasufumi Kaneda; Yu Mu; Hiroshi Kodaira; Shin-ichi Tsunoda; Shinsaku Nakagawa; Tadanori Mayumi
Antitumor activity of tumor necrosis factor-alpha conjugated with polyvinylpyrrolidone on solid tumors in mice.
Cancer research 2000;60(22):6416-20.
2000: Jun Kunisawa; Akiko Okudaira; Y Tsutusmi; Ichiro Takahashi; Tsuyoshi Nakanishi; Hiroshi Kiyono; Tadanori Mayumi
Characterization of mucoadhesive microspheres for the induction of mucosal and systemic immune responses.
Vaccine 2000;19(4-5):589-94.
2000: Shin-ichi Tsunoda; Haruhiko Kamada; Yoko Yamamoto; T Ishikawa; J Matsui; Keiichi Koizumi; Yasufumi Kaneda; Yasuo Tsutsumi; Yoshiyuki Ohsugi; T Hirano; Tadanori Mayumi
Molecular design of polyvinylpyrrolidone-conjugated interleukin-6 for enhancement of in vivo thrombopoietic activity in mice.
Journal of controlled release : official journal of the Controlled Release Society 2000;68(3):335-41.
2000: Susumu Imazu; Shinsaku Nakagawa; Tsuyoshi Nakanishi; Hiroyuki Mizuguchi; H Uemura; O Yamada; Tadanori Mayumi
A novel nonviral vector based on vesicular stomatitis virus.
Journal of controlled release : official journal of the Controlled Release Society 2000;68(2):187-94.
2000: Iwao Ohizumi; N Harada; Kenji Taniguchi; Yasuo Tsutsumi; Shinsaku Nakagawa; Shin-ichi Kaiho; Tadanori Mayumi
Association of CD44 with OTS-8 in tumor vascular endothelial cells.
Biochimica et biophysica acta 2000;1497(2):197-203.
2000: Kenji Taniguchi; N Harada; Iwao Ohizumi; M Kinoshita; Yasuo Tsutsumi; Shinsaku Nakagawa; Shin-ichi Kaiho; Tadanori Mayumi
Molecular cloning and characterization of antigens expressed on rat tumor vascular endothelial cells.
International journal of cancer. Journal international du cancer 2000;86(6):799-805.
2000: T Nakanishi; A Hayashi; Jun Kunisawa; Yasuo Tsutsumi; K Tanaka; Yumi Yashiro-ohtani; M Nakanishi; Hiromi Fujiwara; Toshiyuki Hamaoka; Tadanori Mayumi
Fusogenic liposomes efficiently deliver exogenous antigen through the cytoplasm into the MHC class I processing pathway.
European journal of immunology 2000;30(6):1740-7.
2000: Kenji Taniguchi; N Harada; Iwao Ohizumi; Yasuo Tsutsumi; Shinsaku Nakagawa; Shin-ichi Kaiho; Tadanori Mayumi
Recognition of human activated CD44 by tumor vasculature-targeted antibody.
Biochemical and biophysical research communications 2000;269(3):671-5.
2000: Shin-ichi Tsunoda; Yasuo Tsutsumi; Shinsaku Nakagawa; Tadanori Mayumi
[Targeting therapy using a monoclonal antibody against tumor vascular endothelium].
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 2000;120(3):256-64.
2000: Haruhiko Kamada; Yasuo Tsutsumi; Tetsuya Kihira; Shin-ichi Tsunoda; Yoko Yamamoto; Tadanori Mayumi
In vitro remodeling of tumor vascular endothelial cells using conditioned medium from various tumor cells and their sensitivity to TNF-alpha.
Biochemical and biophysical research communications 2000;268(3):809-13.
2000: Keiko Hojo; Mitsuko Maeda; Y Mu; H Kamada; Y Tsutsumi; Y Nishiyama; T Yoshikawa; K Kurita; Lawrence Block; Tadanori Mayumi; Koichi Kawasaki
Facile synthesis of a chitosan hybrid of a laminin-related peptide and its antimetastatic effect in mice.
The Journal of pharmacy and pharmacology 2000;52(1):67-73.
2000: H Kawano; F Nishi; Y Kamitani; H Ochi; Masaharu Miyake; Tadanori Mayumi; T Hama
Different recognition by peroxisome proliferator structures in rat peroxisomal induction: application of sandwich ELISA using monoclonal antibody against rat peroxisomes.
Biological & pharmaceutical bulletin 2000;23(1):12-6.
1999: Shin-ichi Tsunoda; Iwao Ohizumi; J Matsui; Keiichi Koizumi; Y Wakai; H Makimoto; Yasuo Tsutsumi; Naoki Utoguchi; Kenji Taniguchi; Hiroshi Saito; N Harada; Yoshiyuki Ohsugi; Tadanori Mayumi
Specific binding of TES-23 antibody to tumour vascular endothelium in mice, rats and human cancer tissue: a novel drug carrier for cancer targeting therapy.
British journal of cancer 1999;81(7):1155-61.
1999: Yu Mu; Haruhiko Kamada; Hiroshi Kodaira; Kohji Sato; Yasuo Tsutsumi; Mitsuko Maeda; Koichi Kawasaki; M Nomizu; Yoshihiro Yamada; Tadanori Mayumi
Bioconjugation of laminin-related peptide YIGSR with polyvinyl pyrrolidone increases its antimetastatic effect due to a longer plasma half-life.
Biochemical and biophysical research communications 1999;264(3):763-7.
1999: Iwao Ohizumi; Kenji Taniguchi; Hiroshi Saito; H Kawata; Shin-ichi Tsunoda; H Makimoto; Y Wakai; Yasuo Tsutsumi; Shinsaku Nakagawa; Naoki Utoguchi; Shin-ichi Kaiho; Yoshiyuki Ohsugi; Tadanori Mayumi
Suppression of solid tumor growth by a monoclonal antibody against tumor vasculature in rats: involvement of intravascular thrombosis and fibrinogenesis.
International journal of cancer. Journal international du cancer 1999;82(6):853-9.
1999: Tsuyoshi Nakanishi; Jun Kunisawa; Akira Hayashi; Yasuo Tsutsumi; K Kubo; Shinsaku Nakagawa; Mahito Nakanishi; K Tanaka; Tadanori Mayumi
Positively charged liposome functions as an efficient immunoadjuvant in inducing cell-mediated immune response to soluble proteins.
Journal of controlled release : official journal of the Controlled Release Society 1999;61(1-2):233-40.
1999: Atsushi Hayashi; Tsuyoshi Nakanishi; Jun Kunisawa; Masuo Kondoh; Susumu Imazu; Yasuo Tsutsumi; Keiichi Tanaka; Hiromi Fujiwara; Toshiyuki Hamaoka; Tadanori Mayumi
A novel vaccine delivery system using immunopotentiating fusogenic liposomes.
Biochemical and biophysical research communications 1999;261(3):824-8.
1999: H Makimoto; Keiichi Koizumi; Shin-ichi Tsunoda; Y Wakai; J Matsui; Yasuo Tsutsumi; Shinsaku Nakagawa; Iwao Ohizumi; Kenji Taniguchi; Hiroshi Saito; Naoki Utoguchi; Yoshiyuki Ohsugi; Tadanori Mayumi
Tumor vascular targeting using a tumor-tissue endothelium-specific monoclonal antibody as an effective strategy for cancer chemotherapy.
Biochemical and biophysical research communications 1999;260(2):346-50.
1999: Shin-ichi Tsunoda; T Ishikawa; Yoko Yamamoto; Haruhiko Kamada; Keiichi Koizumi; J Matsui; Yasuo Tsutsumi; Toshio Hirano; Tadanori Mayumi
Enhanced antitumor potency of polyethylene glycolylated tumor necrosis factor-alpha: a novel polymer-conjugation technique with a reversible amino-protective reagent.
The Journal of pharmacology and experimental therapeutics 1999;290(1):368-72.
1999: Haruhiko Kamada; Yasuo Tsutsumi; Shin-ichi Tsunoda; Tetsuya Kihira; Yasufumi Kaneda; Yoko Yamamoto; Shinsaku Nakagawa; Y Horisawa; Tadanori Mayumi
Molecular design of conjugated tumor necrosis factor-alpha: synthesis and characteristics of polyvinyl pyrrolidone modified tumor necrosis factor-alpha.
Biochemical and biophysical research communications 1999;257(2):448-53.
1999: Hajime Miyamoto; Naoki Okada; Tatsunobu Yoshioka; Ryo Suzuki; Kayoko Sakamoto; Asao Katsume; Hiroshi Saito; Yasuo Tsutsumi; K Kubo; Shinsaku Nakagawa; Yoshiyuki Ohsugi; Tadanori Mayumi
Prolongation of the effective duration of cytomedical therapy by re-injecting SK2 hybridoma cells microencapsulated within alginate-poly(L)lysine-alginate membranes into human interleukin-6 transgenic mice.
Biological & pharmaceutical bulletin 1999;22(3):295-7.
1999: Yu Mu; Haruhiko Kamada; Yasufumi Kaneda; Yoko Yamamoto; Hiroshi Kodaira; Shin-ichi Tsunoda; Yasuo Tsutsumi; Mitsuko Maeda; Koichi Kawasaki; M Nomizu; Yoshihiro Yamada; Tadanori Mayumi
Bioconjugation of laminin peptide YIGSR with poly(styrene co-maleic acid) increases its antimetastatic effect on lung metastasis of B16-BL6 melanoma cells.
Biochemical and biophysical research communications 1999;255(1):75-9.
1999: Hiroyuki Mizuguchi; Tsuyoshi Nakanishi; Masuo Kondoh; T Nakagawa; Mahito Nakanishi; T Matsuyama; Yasuo Tsutsumi; Shinsaku Nakagawa; Tadanori Mayumi
Fusion of sendai virus with liposome depends on only F protein, but not HN protein.
Virus research 1999;59(2):191-201.
1999: K Ikeda; Naoki Utoguchi; H Makimoto; H Mizuguchi; Shinsaku Nakagawa; Tadanori Mayumi
Different reactions of aortic and venular endothelial cell monolayers to histamine on macromolecular permeability: role of cAMP, cytosolic Ca2+ and F-actin.
Inflammation 1999;23(1):87-97.
1999: A Watabe; T Yamaguchi; Toru Kawanishi; Eriko Uchida; Akiko Eguchi; Hiroyuki Mizuguchi; Tadanori Mayumi; Mahito Nakanishi; Takao Hayakawa
Target-cell specificity of fusogenic liposomes: membrane fusion-mediated macromolecule delivery into human blood mononuclear cells.
Biochimica et biophysica acta 1999;1416(1-2):339-48.
1999: Mahito Nakanishi; Hiroyuki Mizuguchi; K Ashihara; Takao Senda; Akiko Eguchi; A Watabe; Tsuyoshi Nakanishi; M Kondo; T Nakagawa; A Masago; Jun Okabe; Shigeru Ueda; Tadanori Mayumi; Takao Hayakawa
Gene delivery systems using the Sendai virus.
Molecular membrane biology 1999;16(1):123-7.
1998: Hiroyuki Mizuguchi; Tsutomu Nakagawa; Satoru Toyosawa; Mahito Nakanishi; Susumu Imazu; Tsuyoshi Nakanishi; Yasuo Tsutsumi; Shinsaku Nakagawa; Takao Hayakawa; Naokuni Ijuhin; Tadanori Mayumi
Tumor necrosis factor alpha-mediated tumor regression by the in vivo transfer of genes into the artery that leads to tumors.
Cancer research 1998;58(24):5725-30.
1998: Iwao Ohizumi; Shin-ichi Tsunoda; Kenji Taniguchi; Hiroshi Saito; K Esaki; Keiichi Koizumi; H Makimoto; Y Wakai; J Matsui; Yasuo Tsutsumi; Shinsaku Nakagawa; Naoki Utoguchi; Yoshiyuki Ohsugi; Tadanori Mayumi
Identification of tumor vascular antigens by monoclonal antibodies prepared from rat-tumor-derived endothelial cells.
International journal of cancer. Journal international du cancer 1998;77(4):561-6.
1998: Mitsuko Maeda; Koichi Kawasaki; Y Mu; H Kamada; Y Tsutsumi; Timothy J Smith; Tadanori Mayumi
Amino acids and peptides. XXXIII. A bifunctional poly(ethylene glycol) hybrid of laminin-related peptides.
Biochemical and biophysical research communications 1998;248(3):485-9.
1998: Mahito Nakanishi; H Mizuguchia; K Ashihara; Takao Senda; Teruo Akuta; Jun Okabe; Emi Nagoshi; A Masago; Akiko Eguchi; Yasuhiko Suzuki; Hachiro Inokuchi; A Watabe; Shigeru Ueda; Takao Hayakawa; Tadanori Mayumi
Gene transfer vectors based on Sendai virus.
Journal of controlled release : official journal of the Controlled Release Society 1998;54(1):61-8.
1998: M Kadono; K Kubo; H Miyazaki; N Tojyo; Shinsaku Nakagawa; K Miyashita; Takeshi Imanishi; J H Rytting; Tadanori Mayumi
Enhanced in vitro percutaneous penetration of salicylate by ion pair formation with alkylamines.
Biological & pharmaceutical bulletin 1998;21(6):599-603.
1998: Mitsuko Maeda; Y Izuno; Koichi Kawasaki; Y Kaneda; Y Mu; Y Tsutsumi; Shinsaku Nakagawa; Tadanori Mayumi
Amino acids and peptides. XXXI. Preparation of analogs of the laminin-related peptide YIGSR and their inhibitory effect on experimental metastasis.
Chemical & pharmaceutical bulletin 1998;46(2):347-50.
1998: Yasufumi Kaneda; Yoko Yamamoto; Haruhiko Kamada; Shin-ichi Tsunoda; Yasuo Tsutsumi; Toshio Hirano; Tadanori Mayumi
Antitumor activity of tumor necrosis factor alpha conjugated with divinyl ether and maleic anhydride copolymer on solid tumors in mice.
Cancer research 1998;58(2):290-5.
1997: Mitsuko Maeda; Y Izuno; Koichi Kawasaki; Y Kaneda; Y Mu; Y Tsutsumi; K W Lem; Tadanori Mayumi
Amino acids and peptides. XXXII: A bifunctional poly(ethylene glycol) hybrid of fibronectin-related peptides.
Biochemical and biophysical research communications 1997;241(2):595-8.
1997: Tsuyoshi Nakanishi; Jun Kunisawa; Atsushi Hayashi; Yasuo Tsutsumi; K Kubo; Shinsaku Nakagawa; Hiromi Fujiwara; Toshiyuki Hamaoka; Tadanori Mayumi
Positively charged liposome functions as an efficient immunoadjuvant in inducing immune responses to soluble proteins.
Biochemical and biophysical research communications 1997;240(3):793-7.
1997: Mitsuko Maeda; Y Izuno; Koichi Kawasaki; Y Kaneda; Y Mu; Y Tsutsumi; Shinsaku Nakagawa; Tadanori Mayumi
Amino acids and peptides. XXX. Preparation of Arg-Gly-Asp (RGD) hybrids with poly(ethylene glycol) analogs and their antimetastatic effect.
Chemical & pharmaceutical bulletin 1997;45(11):1788-92.
1997: Yasufumi Kaneda; Yoko Yamamoto; Shin-ichi Tsunoda; Haruhiko Kamada; Yasuo Tsutsumi; Toshio Hirano; Tadanori Mayumi
Bioconjugation of tumor necrosis factor-alpha with the copolymer of divinyl ether and maleic anhydride increasing its antitumor potency.
Biochemical and biophysical research communications 1997;239(1):160-5.
1997: Yasufumi Kaneda; Y Yamamoto; Naoki Okada; Y Tsutsuml; Shinsaku Nakagawa; M Kakiuch; Mitsuko Maeda; Koichi Kawasaki; Tadanori Mayumi
Antimetastatic effect of synthetic Glu-Ile-Leu-Asp-Val peptide derivatives containing D-amino acids.
Anti-cancer drugs 1997;8(7):702-7.
1997: Iwao Ohizumi; Shin-ichi Tsunoda; Kenji Taniguchi; Hiroshi Saito; K Esaki; H Makimoto; Y Wakai; Yasuo Tsutsumi; Shinsaku Nakagawa; Naoki Utoguchi; Shin-ichi Kaiho; Yoshiyuki Ohsugi; Tadanori Mayumi
Antibody-based therapy targeting tumor vascular endothelial cells suppresses solid tumor growth in rats.
Biochemical and biophysical research communications 1997;236(2):493-6.
1997: Hiroyuki Mizuguchi; Tsutomu Nakagawa; Y Morioka; Susumu Imazu; Mahito Nakanishi; T Kondo; Takao Hayakawa; Tadanori Mayumi
Cytoplasmic gene expression system enhances the efficiency of cationic liposome-mediated in vivo gene transfer into mouse brain.
Biochemical and biophysical research communications 1997;234(1):15-8.
1997: Naoki Utoguchi; T Nakata; H H Cheng; K Ikeda; H Makimoto; Y Mu; Shinsaku Nakagawa; Motomasa Kobayashi; I Kitagawa; Tadanori Mayumi
Bruceine B, a potent inhibitor of leukocyte-endothelial cell adhesion.
Inflammation 1997;21(2):223-33.
1997: Naoki Okada; Hajime Miyamoto; Tatsunobu Yoshioka; Asao Katsume; Hiroshi Saito; Keigo Yorozu; Otoya Ueda; Shinsaku Nakagawa; Yoshiyuki Ohsugi; Tadanori Mayumi
Therapeutic effect of cytomedicine on mesangio-proliferative glomerulonephritis in human interleukin-6 transgenic mice.
Biological & pharmaceutical bulletin 1997;20(3):255-8.
1997: Naoki Okada; Hajime Miyamoto; Tatsunobu Yoshioka; Asao Katsume; Hiroshi Saito; Keigo Yorozu; Otoya Ueda; Norio Itoh; Hiroyuki Mizuguchi; Shinsaku Nakagawa; Yoshiyuki Ohsugi; Tadanori Mayumi
Cytomedical therapy for IgG1 plasmacytosis in human interleukin-6 transgenic mice using hybridoma cells microencapsulated in alginate-poly(L)lysine-alginate membrane.
Biochimica et biophysica acta 1997;1360(1):53-63.
1997: Naoki Okada; Hajime Miyamoto; Tatsunobu Yoshioka; Kayoko Sakamoto; Asao Katsume; Hiroshi Saito; Shinsaku Nakagawa; Yoshiyuki Ohsugi; Tadanori Mayumi
Immunological studies of SK2 hybridoma cells microencapsulated with alginate-poly(L)lysine-alginate (APA) membrane following allogeneic transplantation.
Biochemical and biophysical research communications 1997;230(3):524-7.
1997: Yasuo Tsutsumi; Shin-ichi Tsunoda; Haruhiko Kamada; Tetsuya Kihira; Yasufumi Kaneda; Yoshiyuki Ohsugi; Tadanori Mayumi
PEGylation of interleukin-6 effectively increases its thrombopoietic potency.
Thrombosis and haemostasis 1997;77(1):168-73.
1996: Koichi Kawasaki; M Maeda; S Inoue; Y Yamashiro; Y Kaneda; Y Mu; Y Tsutsumi; Shinsaku Nakagawa; Tadanori Mayumi
Amino acids and peptides. XXIX. Synthesis and antimetastatic effects of peptides and peptide-poly(ethylene glycol) hybrids related to the core sequence of the type III connecting segment domain of fibronectin.
Biological & pharmaceutical bulletin 1996;19(12):1574-9.
1996: I Kitagawa; T Mahmud; K Yokota; Shinsaku Nakagawa; Tadanori Mayumi; Motomasa Kobayashi; H Shibuya
Indonesian medicinal plants. XVII. Characterization of quassinoids from the stems of Quassia indica.
Chemical & pharmaceutical bulletin 1996;44(11):2009-14.
1996: Yasuo Tsutsumi; Shin-ichi Tsunoda; Yasufumi Kaneda; Haruhiko Kamada; Tetsuya Kihira; Shinsaku Nakagawa; Yoko Yamamoto; Y Horisawa; Tadanori Mayumi
In vivo anti-tumor efficacy of polyethylene glycol-modified tumor necrosis factor-alpha against tumor necrosis factor-resistant tumors.
Japanese journal of cancer research : Gann 1996;87(10):1078-85.
1996: Yasuo Tsutsumi; Shin-ichi Tsunoda; Haruhiko Kamada; Tetsuya Kihira; Shinsaku Nakagawa; Yasufumi Kaneda; T Kanamori; Tadanori Mayumi
Molecular design of hybrid tumour necrosis factor-alpha. II: The molecular size of polyethylene glycol-modified tumour necrosis factor-alpha affects its anti-tumour potency.
British journal of cancer 1996;74(7):1090-5.
1996: Naoki Okada; M Fushimi; Y Nagata; T Fukunaga; Yasuo Tsutsumi; Shinsaku Nakagawa; Tadanori Mayumi
Evaluation of angiogenic inhibitors with an in vivo quantitative angiogenesis method using agarose microencapsulation and mouse hemoglobin enzyme-linked immunosorbent assay.
Japanese journal of cancer research : Gann 1996;87(9):952-7.
1996: Yasuo Tsutsumi; Tetsuya Kihira; Shin-ichi Tsunoda; Haruhiko Kamada; Shinsaku Nakagawa; Yasufumi Kaneda; T Kanamori; Tadanori Mayumi
Molecular design of hybrid tumor necrosis factor-alpha III: polyethylene glycol-modified tumor necrosis factor-alpha has markedly enhanced antitumor potency due to longer plasma half-life and higher tumor accumulation.
The Journal of pharmacology and experimental therapeutics 1996;278(3):1006-11.
1996: Naoki Okada; Yasufumi Kaneda; H Miyamoto; Yoko Yamamoto; H Mizuguchi; Yasuo Tsutsumi; Shinsaku Nakagawa; Tadanori Mayumi
Selective enhancement by tumor necrosis factor-alpha of vascular permeability of new blood vessels induced with agarose hydrogel-entrapped Meth-A fibrosarcoma cells.
Japanese journal of cancer research : Gann 1996;87(8):831-6.
1996: Motomasa Kobayashi; T Mahmud; H Tajima; W Wang; S Aoki; Shinsaku Nakagawa; Tadanori Mayumi; I Kitagawa
Marine natural products. XXXVI. Biologically active polyacetylenes, adociacetylenes A, B, C, and D, from an Okinawan Marine sponge of Adocia sp.
Chemical & pharmaceutical bulletin 1996;44(4):720-4.
1996: Naoki Utoguchi; Hiroyuki Mizuguchi; K Saeki; K Ikeda; S Nakagawa; Tadanori Mayumi
Effects of rat hepatocytes on macromolecular permeability of bovine aortic endothelial cell monolayer.
International journal of microcirculation, clinical and experimental / sponsored by the European Society for Microcirculation 1996;16(2):105-10.
1996: Hiroyuki Mizuguchi; Tsuyoshi Nakanishi; Mahito Nakanishi; Tsutomu Nakagawa; Shinsaku Nakagawa; Tadanori Mayumi
Intratumor administration of fusogenic liposomes containing fragment A of diphtheria toxin suppresses tumor growth.
Cancer letters 1996;100(1-2):63-9.
1996: Hiroyuki Mizuguchi; Mahito Nakanishi; Tsuyoshi Nakanishi; Tsutomu Nakagawa; Shinsaku Nakagawa; Tadanori Mayumi
Application of fusogenic liposomes containing fragment A of diphtheria toxin to cancer therapy.
British journal of cancer 1996;73(4):472-6.
1996: Hiroyuki Mizuguchi; Tsutomu Nakagawa; Mahito Nakanishi; Susumu Imazu; Shinsaku Nakagawa; Tadanori Mayumi
Efficient gene transfer into mammalian cells using fusogenic liposome.
Biochemical and biophysical research communications 1996;218(1):402-7.
1996: Naoki Utoguchi; Hiroyuki Mizuguchi; A Dantakean; H Makimoto; Y Wakai; Yasuo Tsutsumi; Shinsaku Nakagawa; Tadanori Mayumi
Effect of tumour cell-conditioned medium on endothelial macromolecular permeability and its correlation with collagen.
British journal of cancer 1996;73(1):24-8.
1995: Naoki Okada; M Fushimi; Y Nagata; T Fukunaga; Yasuo Tsutsumi; Shinsaku Nakagawa; Tadanori Mayumi
A quantative in vivo method of analyzing human tumor-induced angiogenesis in mice using agarose microencapsulation and hemoglobin enzyme-linked immunosorbent assay.
Japanese journal of cancer research : Gann 1995;86(12):1182-8.
1995: Koichi Kawasaki; M Namikawa; Y Yamashiro; Y Iwai; T Hama; Y Tsutsumi; S Yamamoto; Shinsaku Nakagawa; Tadanori Mayumi
Amino acids and peptides. XXV. Preparation of fibronectin-related peptide poly(ethylene glycol) hybrids and their inhibitory effect on experimental metastasis.
Chemical & pharmaceutical bulletin 1995;43(12):2133-8.
1995: Hiroyuki Mizuguchi; A Fujii; Naoki Utoguchi; Shinsaku Nakagawa; Tadanori Mayumi
Glial-conditioned medium elevates alkaline phosphatase activity in cultured bovine aortic endothelial cells.
Microvascular research 1995;50(1):129-32.
1995: Yasuo Tsutsumi; Shinsaku Nakagawa; Tadanori Mayumi
[Chemical modification of IL-6 with PEG].
Seikagaku. The Journal of Japanese Biochemical Society 1995;67(6):465-9.
1995: Yasuo Tsutsumi; Tetsuya Kihira; Shin-ichi Tsunoda; T Kanamori; Shinsaku Nakagawa; Tadanori Mayumi
Molecular design of hybrid tumour necrosis factor alpha with polyethylene glycol increases its anti-tumour potency.
British journal of cancer 1995;71(5):963-8.
1995: Naoki Utoguchi; K Ikeda; K Saeki; N Oka; Hiroyuki Mizuguchi; K Kubo; S Nakagawa; Tadanori Mayumi
Ascorbic acid stimulates barrier function of cultured endothelial cell monolayer.
Journal of cellular physiology 1995;163(2):393-9.
1995: Naoki Utoguchi; Hiroyuki Mizuguchi; K Saeki; Kimimasa Ikeda; Yasuo Tsutsumi; Shinsaku Nakagawa; Tadanori Mayumi
Tumor-conditioned medium increases macromolecular permeability of endothelial cell monolayer.
Cancer letters 1995;89(1):7-14.
1995: Naoki Utoguchi; A Dantakean; H Makimoto; Y Wakai; Yasuo Tsutsumi; Shinsaku Nakagawa; Tadanori Mayumi
Isolation and properties of tumor-derived endothelial cells from rat KMT-17 fibrosarcoma.
Japanese journal of cancer research : Gann 1995;86(2):193-201.
1995: Yasufumi Kaneda; S Yamamoto; Tetsuya Kihira; Yasuo Tsutsumi; Shinsaku Nakagawa; M Miyake; K Kawasaki; Tadanori Mayumi
Synthetic cell-adhesive laminin peptide YIGSR conjugated with polyethylene glycol has improved antimetastatic activity due to a longer half-life in blood.
Invasion & metastasis 1995;15(3-4):156-62.
1994: Yasuo Tsutsumi; Tetsuya Kihira; Shin-ichi Tsunoda; K Kubo; M Miyake; T Kanamori; Shinsaku Nakagawa; Tadanori Mayumi
Intravenous administration of polyethylene glycol-modified tumor necrosis factor-alpha completely regressed solid tumor in Meth-A murine sarcoma model.
Japanese journal of cancer research : Gann 1994;85(12):1185-8.
1994: Hiroyuki Mizuguchi; Y Hashioka; Naoki Utoguchi; K Kubo; Shinsaku Nakagawa; Tadanori Mayumi
A comparison of drug transport through cultured monolayers of bovine brain capillary and bovine aortic endothelial cells.
Biological & pharmaceutical bulletin 1994;17(10):1385-90.
1994: S Yamamoto; Yasufumi Kaneda; N Okada; Shinsaku Nakagawa; K Kubo; S Inoue; M Maeda; Y Yamashiro; K Kawasaki; Tadanori Mayumi
Antimetastatic effects of synthetic peptides containing the core sequence of the type III connecting segment domain (IIICS) of fibronectin.
Anti-cancer drugs 1994;5(4):424-8.
1994: Hiroyuki Mizuguchi; Y Hashioka; A Fujii; Naoki Utoguchi; K Kubo; Shinsaku Nakagawa; Akemichi Baba; Tadanori Mayumi
Glial extracellular matrix modulates gamma-glutamyl transpeptidase activity in cultured bovine brain capillary and bovine aortic endothelial cells.
Brain research 1994;651(1-2):155-9.
1994: M Maeda; Koichi Kawasaki; Tadanori Mayumi; M Takahashi; H Kaneto
Amino acids and peptides. XXII. Preparation and antinociceptive effect of [D-Ala2]Leu-enkephalin-poly(ethylene glycol) hybrid.
Biological & pharmaceutical bulletin 1994;17(6):823-5.
1994: Koichi Kawasaki; T Murakami; M Namikawa; T Mizuta; Y Iwai; Y Yamashiro; T Hama; S Yamamoto; Tadanori Mayumi
Amino acids and peptides. XXI. Laminin-related peptide analogs including poly(ethylene glycol) hybrids and their inhibitory effect on experimental metastasis.
Chemical & pharmaceutical bulletin 1994;42(4):917-21.
1994: Koichi Kawasaki; T Murakami; K Koshino; M Namikawa; M Maeda; T Hama; Tadanori Mayumi
Amino acids and peptides. XX. Preparation of beta-cyclododecyl aspartate and its application to synthesis of fibronectin- and laminin-related peptides.
Chemical & pharmaceutical bulletin 1994;42(4):792-5.
1994: Y Kawai; S Ohnishi; M Miyake; T Hama; Tadanori Mayumi
Flow cytometric analysis of mouse sperm using monoclonal anti-sperm antibody A-1.
Molecular reproduction and development 1994;37(3):293-8.
1994: Yasuo Tsutsumi; Tetsuya Kihira; S Yamamoto; K Kubo; Shinsaku Nakagawa; M Miyake; Y Horisawa; T Kanamori; H Ikegami; Tadanori Mayumi
Chemical modification of natural human tumor necrosis factor-alpha with polyethylene glycol increases its anti-tumor potency.
Japanese journal of cancer research : Gann 1994;85(1):9-12.
1993: Koichi Kawasaki; M Maeda; Y Yamashiro; Tadanori Mayumi; M Takahashi; H Kaneto
Amino acids and peptides. XIX. Preparation of enkephalin-poly(ethylene glycol) hybrid and evaluation of its analgesic activity.
Chemical & pharmaceutical bulletin 1993;41(11):2053-4.
1993: Y Kawai; A Yoshida; S Nakagawa; T Hama; Tadanori Mayumi
Effect of bredinin on early embryonic development in mice.
Biological & pharmaceutical bulletin 1993;16(2):133-6.
1993: Y Kawai; S Ohnishi; M Uehara; T Hama; Tadanori Mayumi
Effect of a monoclonal anti-sperm antibody (A-1) on in vitro fertilization in the mouse.
Biological & pharmaceutical bulletin 1993;16(2):116-9.
1992: Junichi Kitanaka; Hisashi Hashimoto; M Gotoh; Tadanori Mayumi; Akemichi Baba
Mechanism of extracellular ATP-stimulated phosphoinositide hydrolysis in rat glioma C6 cells.
The Journal of pharmacology and experimental therapeutics 1992;263(3):1248-52.
1992: S Nakagawa; T Hama; Tadanori Mayumi
Effect of bredinin on the primary culture of fetal mouse cells and adult mouse lung cells.
Chemical & pharmaceutical bulletin 1992;40(11):3009-12.
1991: Koichi Kawasaki; M Namikawa; Y Yamashiro; T Hama; Tadanori Mayumi
Preparation of [Arg-Gly-Asp]-[amino-poly(ethylene glycol)] hybrids and their inhibitory effect on experimental metastasis.
Chemical & pharmaceutical bulletin 1991;39(12):3373-5.
1991: Y Kawai; K Funakoshi; T Hama; Tadanori Mayumi
Studies on mouse sperm binding molecule (ligand) to egg zona pellucida. II. Purification of ligand molecule from cauda epididymal sperm.
Journal of pharmacobio-dynamics 1991;14(5):237-43.
1991: Y Kawai; H Shimaji; T Hama; Tadanori Mayumi
Studies on mouse sperm lectin; the existence and the participation in sperm-egg binding.
Journal of pharmacobio-dynamics 1991;14(5):244-9.
1991: Y Kawai; K Yoshikawa; T Hama; Tadanori Mayumi
Studies on egg zona pellucida-binding molecule (ligand) of mouse sperm. I. Sperm maturation and zona-binding ability.
Journal of pharmacobio-dynamics 1991;14(5):231-6.
1991: Koichi Kawasaki; M Namikawa; T Murakami; T Mizuta; Y Iwai; T Hama; Tadanori Mayumi
Amino acids and peptides. XIV. Laminin related peptides and their inhibitory effect on experimental metastasis formation.
Biochemical and biophysical research communications 1991;174(3):1159-62.
1990: Masaru Okabe; M Nagira; Y Kawai; S Matzno; T Mimura; Tadanori Mayumi
A human sperm antigen possibly involved in binding and/or fusion with zona-free hamster eggs.
Fertility and sterility 1990;54(6):1121-6.
1989: Y Kawai; T Hama; Tadanori Mayumi; Masaru Okabe; S Matzno; Y Kohama; T Mimura
Flow cytometric analysis of mouse sperm using monoclonal anti-sperm antibody OBF13.
Journal of reproductive immunology 1989;16(1):71-82.
1987: N Itoh; T Toyohama; Hiroshi Okamoto; H Kawano; Tadanori Mayumi; T Hama
Involvement of inflammatory leukocytes in hepatic induction of T-kininogen in rat.
Inflammation 1987;11(3):345-52.