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George McAllister

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Chemicals & Drugs

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Maria G Beconi; Fred Brookfield; Roland W Bürli; Steven Clifton; Lynsey Crowley; Celia Dominguez; Alan F Haughan; Kim Matthews; George McAllister; Lara Moumné; Ignacio Munoz-Sanjuan; Catherine O'Connell; Hannah Pett; Donna L Smith; Julie Vann; Ben Woodman; Dawn Yates; Omar Aziz; Gillian P Bates; Vahri Beaumont
Oral administration of the pimelic diphenylamide HDAC inhibitor HDACi 4b is unsuitable for chronic inhibition of HDAC activity in the CNS in vivo.
James G Bilsland; Alan Wheeldon; Andrew Mead; Petr Znamenskiy; Sarah Almond; Kerry A Waters; Matthew Thakur; Vahri Beaumont; Timothy P Bonnert; Robert Heavens; Paul Whiting; George McAllister; Ignacio Munoz-Sanjuan
Behavioral and neurochemical alterations in mice deficient in anaplastic lymphoma kinase suggest therapeutic potential for psychiatric indications.
Vahri Beaumont; Sally-Anne Thompson; Fahd Choudhry; Hugh Nuthall; Helmut Glantschnig; Lorraine Lipfert; Gabriela R David; Christopher J Swain; George McAllister; Ignacio Munoz-Sanjuan
Evidence for an enhancement of excitatory transmission in adult CNS by Wnt signaling pathway modulation.

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All Publications

2012: Maria G Beconi; Fred Brookfield; Roland W Bürli; Steven Clifton; Lynsey Crowley; Celia Dominguez; Alan F Haughan; Kim Matthews; George McAllister; Lara Moumné; Ignacio Munoz-Sanjuan; Catherine O'Connell; Hannah Pett; Donna L Smith; Julie Vann; Ben Woodman; Dawn Yates; Omar Aziz; Gillian P Bates; Vahri Beaumont
Oral administration of the pimelic diphenylamide HDAC inhibitor HDACi 4b is unsuitable for chronic inhibition of HDAC activity in the CNS in vivo.
PloS one 2012;7(9):e44498.
2008: James G Bilsland; Alan Wheeldon; Andrew Mead; Petr Znamenskiy; Sarah Almond; Kerry A Waters; Matthew Thakur; Vahri Beaumont; Timothy P Bonnert; Robert Heavens; Paul Whiting; George McAllister; Ignacio Munoz-Sanjuan
Behavioral and neurochemical alterations in mice deficient in anaplastic lymphoma kinase suggest therapeutic potential for psychiatric indications.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2008;33(3):685-700.
2007: Vahri Beaumont; Sally-Anne Thompson; Fahd Choudhry; Hugh Nuthall; Helmut Glantschnig; Lorraine Lipfert; Gabriela R David; Christopher J Swain; George McAllister; Ignacio Munoz-Sanjuan
Evidence for an enhancement of excitatory transmission in adult CNS by Wnt signaling pathway modulation.
Molecular and cellular neurosciences 2007;35(4):513-24.
2007: Kamran Salim; Paul C Guest; Heather A Skynner; James G Bilsland; Timothy P Bonnert; George McAllister; Ignacio Munoz-Sanjuan
Identification of proteomic changes during differentiation of adult mouse subventricular zone progenitor cells.
Stem cells and development 2007;16(1):143-65.
2006: James G Bilsland; Christine Haldon; Julie Goddard; Kevin Oliver; Fraser Murray; Alan Wheeldon; Janine Cumberbatch; George McAllister; Ignacio Munoz-Sanjuan
A rapid method for the quantification of mouse hippocampal neurogenesis in vivo by flow cytometry. Validation with conventional and enhanced immunohistochemical methods.
Journal of neuroscience methods 2006;157(1):54-63.
2006: Timothy P Bonnert; James G Bilsland; Paul C Guest; Robert P Heavens; Donna McLaren; Charlotte Dale; Matthew Thakur; George McAllister; Ignacio Munoz-Sanjuan
Molecular characterization of adult mouse subventricular zone progenitor cells during the onset of differentiation.
The European journal of neuroscience 2006;24(3):661-75.
2005: Martin R Guscott; Linda J Bristow; Karen L Hadingham; Thomas W Rosahl; Margaret S Beer; Josephine A Stanton; Frances A Bromidge; Andrew P Owens; Ian T Huscroft; Janice Myers; Nadia M J Rupniak; Smita Patel; Paul J Whiting; Peter H Hutson; Kevin C F Fone; S M Biello; Janusz J Kulagowski; George McAllister
Genetic knockout and pharmacological blockade studies of the 5-HT7 receptor suggest therapeutic potential in depression.
Neuropharmacology 2005;48(4):492-502.
2004: Paul C Guest; Michael R Knowles; Sylvain Molon-Noblot; Kamran Salim; David Smith; Fraser Murray; Philippe Laroque; Stephen P Hunt; Carmen De Felipe; Nadia M J Rupniak; George McAllister
Mechanisms of action of the antidepressants fluoxetine and the substance P antagonist L-000760735 are associated with altered neurofilaments and synaptic remodeling.
Brain research 2004;1002(1-2):1-10.
2003: Michael R Knowles; Sandra Cervino; Heather A Skynner; Stephen P Hunt; Carmen De Felipe; Kamran Salim; Georgina Meneses-Lorente; George McAllister; Paul C Guest
Multiplex proteomic analysis by two-dimensional differential in-gel electrophoresis.
Proteomics 2003;3(7):1162-71.
2003: Martin R Guscott; E Egan; Gina P Cook; Josephine A Stanton; Margaret S Beer; Thomas W Rosahl; S Hartmann; Janusz J Kulagowski; George McAllister; Kevin C F Fone; Peter H Hutson
The hypothermic effect of 5-CT in mice is mediated through the 5-HT7 receptor.
Neuropharmacology 2003;44(8):1031-7.
2003: Janine N Bresnick; Heather A Skynner; Kerry L Chapman; Andrew D Jack; Elize Zamiara; Paul Negulescu; Kevin Beaumont; Smita Patel; George McAllister
Identification of signal transduction pathways used by orphan g protein-coupled receptors.
Assay and drug development technologies 2003;1(2):239-49.
2002: Peter B Simpson; Israel Ramos Villullas; Irina Schurov; Julie Kerby; Rachel Millard; Christine Haldon; Margaret S Beer; George McAllister
Native and recombinant human Edg4 receptor-mediated Ca(2+) signalling.
Assay and drug development technologies 2002;1(1 Pt 1):31-40.
2002: Heather A Skynner; Thomas W Rosahl; Michael R Knowles; Kamran Salim; Lee Reid; Rosa Cothliff; George McAllister; Paul C Guest
Alterations of stress related proteins in genetically altered mice revealed by two-dimensional differential in-gel electrophoresis analysis.
Proteomics 2002;2(8):1018-25.
2002: Kamran Salim; Tim Fenton; Jamil Bacha; Hector Urien-Rodriguez; Timothy P Bonnert; Heather A Skynner; Emma Watts; Julie Kerby; Anne Heald; Margaret Beer; George McAllister; Paul C Guest
Oligomerization of G-protein-coupled receptors shown by selective co-immunoprecipitation.
The Journal of biological chemistry 2002;277(18):15482-5.
2001: Michael G N Russell; R J Baker; L Barden; Margaret S Beer; Linda J Bristow; Howard B Broughton; M Knowles; George McAllister; Smita Patel; José L Castro
N-Arylsulfonylindole derivatives as serotonin 5-HT(6) receptor ligands.
Journal of medicinal chemistry 2001;44(23):3881-95.
2001: Emma Handford; David Smith; Louise Hewson; George McAllister; Margaret S Beer
Edg2 receptor distribution in adult rat brain.
Neuroreport 2001;12(4):757-60.
2000: S E George; Marie-Therese Schaeffer; Doris F Cully; Margaret S Beer; George McAllister
A high-throughput glow-type aequorin assay for measuring receptor-mediated changes in intracellular calcium levels.
Analytical biochemistry 2000;286(2):231-7.
2000: Paul C Guest; Kamran Salim; Heather A Skynner; S E George; Janine N Bresnick; George McAllister
Identification and characterization of a truncated variant of the 5-hydroxytryptamine(2A) receptor produced by alternative splicing.
Brain research 2000;876(1-2):238-44.
2000: George McAllister; Josephine A Stanton; Kamran Salim; Emma Handford; Margaret S Beer
Edg2 receptor functionality: gialpha1 coexpression and fusion protein studies.
Molecular pharmacology 2000;58(2):407-12.
2000: DS Im; CE Heise; nicolas ancellin; Brian F O'Dowd; Gan-Ju Shei; Robert P Heavens; MR Rigby; T Hla; Suzanne Mandala; George McAllister; Susan R George; Kevin R Lynch
Characterization of a novel sphingosine 1-phosphate receptor, Edg-8.
The Journal of biological chemistry 2000;275(19):14281-6.
2000: Margaret S Beer; Josephine A Stanton; Kamran Salim; M Rigby; Robert P Heavens; David Smith; George McAllister
EDG receptors as a therapeutic target in the nervous system.
Annals of the New York Academy of Sciences 2000;905():118-31.
1999: dominic Surry; George McAllister; Georgina Meneses-Lorente; David C Evans
High throughput ribonuclease protection assay for the determination of CYP3A mRNA induction in cultured rat hepatocytes.
Xenobiotica; the fate of foreign compounds in biological systems 1999;29(8):827-38.
1998: Margaret S Beer; M A Heald; George McAllister; Josephine A Stanton
Pharmacological characterisation of a cloned dog 5-HT1B receptor cell line.
European journal of pharmacology 1998;360(1):117-21.
1998: D Smith; Duncan Shaw; R Hopkins; George McAllister; R Hill; DJ Sirinathsinghji; Jenny Longmore
Development and characterisation of human 5-HT1B- or 5-HT1D-receptor specific antibodies as unique research tools.
Journal of neuroscience methods 1998;80(2):155-61.
1998: N C Stefanis; Janine N Bresnick; R W Kerwin; W N Schofield; George McAllister
Elevation of D4 dopamine receptor mRNA in postmortem schizophrenic brain.
Brain research. Molecular brain research 1998;53(1-2):112-9.
1997: Jenny Longmore; Duncan Shaw; D Smith; R Hopkins; George McAllister; J D Pickard; DJ Sirinathsinghji; A J Butler; Raymond G Hill
Differential distribution of 5HT1D- and 5HT1B-immunoreactivity within the human trigemino-cerebrovascular system: implications for the discovery of new antimigraine drugs.
Cephalalgia : an international journal of headache 1997;17(8):833-42.
1997: Smita Patel; S Freedman; Kerry L Chapman; F Emms; AE Fletcher; M Knowles; Rose Marwood; George McAllister; Janice Myers; Neil R Curtis; Janusz J Kulagowski; Paul D Leeson; Mark P Ridgill; M Graham; S Matheson; D Rathbone; Alan P Watt; Linda J Bristow; Nadia M J Rupniak; E Baskin; Joseph J Lynch; C Ian Ragan
Biological profile of L-745,870, a selective antagonist with high affinity for the dopamine D4 receptor.
The Journal of pharmacology and experimental therapeutics 1997;283(2):636-47.
1997: Paul J Whiting; George McAllister; Timothy P Bonnert; Robert P Heavens; MR Rigby; DJ Sirinathsinghji; G Marshall; Sally-Anne Thompson; Keith A Wafford
The use of expressed sequence tag databases to identify novel human gamma-aminobutyric acid type receptor genes.
Biochemical Society transactions 1997;25(3):817-9.
1997: Paul J Whiting; George McAllister; D Vassilatis; Timothy P Bonnert; Robert P Heavens; DW Smith; Louise Hewson; Ruth O'Donnell; MR Rigby; DJ Sirinathsinghji; G Marshall; Sally-Anne Thompson; Keith A Wafford; D Vasilatis
Neuronally restricted RNA splicing regulates the expression of a novel GABAA receptor subunit conferring atypical functional properties [corrected; erratum to be published].
The Journal of neuroscience : the official journal of the Society for Neuroscience 1997;17(13):5027-37.
1995: N A Brown; George McAllister; D Weinberg; G Milligan; Guy R Seabrook
Involvement of G-protein alpha il subunits in activation of G-protein gated inward rectifying K+ channels (GIRK1) by human NPY1 receptors.
British journal of pharmacology 1995;116(5):2346-8.
1995: George McAllister; M R Knowles; S M Ward-Booth; H A Sinclair; Smita Patel; Rose Marwood; F Emms; S Patel; A Smith; Guy R Seabrook
Functional coupling of human D2, D3, and D4 dopamine receptors in HEK293 cells.
Journal of receptor and signal transduction research 1995;15(1-4):267-81.
1994: R Bone; L Frank; J P Springer; S J Pollack; S A Osborne; John R Atack; M R Knowles; George McAllister; C Ian Ragan; Howard B Broughton
Structural analysis of inositol monophosphatase complexes with substrates.
Biochemistry 1994;33(32):9460-7.
1994: Guy R Seabrook; M Knowles; N Brown; J Myers; H Sinclair; Smita Patel; S B Freedman; George McAllister
Pharmacology of high-threshold calcium currents in GH4C1 pituitary cells and their regulation by activation of human D2 and D4 dopamine receptors.
British journal of pharmacology 1994;112(3):728-34.
1994: S J Pollack; John R Atack; M R Knowles; George McAllister; C Ian Ragan; R Baker; S R Fletcher; L L Iversen; Howard B Broughton
Mechanism of inositol monophosphatase, the putative target of lithium therapy.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(13):5766-70.
1994: Guy R Seabrook; George McAllister; M R Knowles; J Myers; H Sinclair; Smita Patel; S B Freedman; J A Kemp
Depression of high-threshold calcium currents by activation of human D2 (short) dopamine receptors expressed in differentiated NG108-15 cells.
British journal of pharmacology 1994;111(4):1061-6.
1994: Guy R Seabrook; J A Kemp; S B Freedman; Smita Patel; H A Sinclair; George McAllister
Functional expression of human D3 dopamine receptors in differentiated neuroblastoma x glioma NG108-15 cells.
British journal of pharmacology 1994;111(2):391-3.
1994: S B Freedman; Smita Patel; Rose Marwood; F Emms; Guy R Seabrook; M R Knowles; George McAllister
Expression and pharmacological characterization of the human D3 dopamine receptor.
The Journal of pharmacology and experimental therapeutics 1994;268(1):417-26.
1993: Michael G Gore; P Greasley; George McAllister; C Ian Ragan
Mammalian inositol monophosphatase: the identification of residues important for the binding of Mg2+ and Li+ ions using fluorescence spectroscopy and site-directed mutagenesis.
The Biochemical journal 1993;296 ( Pt 3)():811-5.
1993: S J Pollack; M R Knowles; John R Atack; Howard B Broughton; C Ian Ragan; S Osborne; George McAllister
Probing the role of metal ions in the mechanism of inositol monophosphatase by site-directed mutagenesis.
European journal of biochemistry / FEBS 1993;217(1):281-7.
1993: George McAllister; M R Knowles; S Patel; Rose Marwood; F Emms; Guy R Seabrook; M Graziano; D Borkowski; P J Hey; S B Freedman
Characterisation of a chimeric hD3/D2 dopamine receptor expressed in CHO cells.
FEBS letters 1993;324(1):81-6.
1993: Margaret S Beer; D N Middlemiss; George McAllister
5-HT1-like receptors: six down and still counting.
Trends in pharmacological sciences 1993;14(6):228-31.
1992: Guy R Seabrook; Smita Patel; Rose Marwood; F Emms; M R Knowles; S B Freedman; George McAllister
Stable expression of human D3 dopamine receptors in GH4C1 pituitary cells.
FEBS letters 1992;312(2-3):123-6.
1992: P J Greasley; Michael G Gore; C Ian Ragan; M R Knowles; N S Gee; George McAllister
Bovine inositol monophosphatase; observation of the modification of a cysteine residue using protein fluorescence.
Biochemical Society transactions 1992;20(3):290S.
1992: M R Knowles; N Gee; George McAllister; C Ian Ragan; P J Greasley; Michael G Gore
Bovine inositol monophosphatase. Modification, identification and mutagenesis of reactive cysteine residues.
The Biochemical journal 1992;285 ( Pt 2)():461-8.
1992: George McAllister; Amanda Charlesworth; C Snodin; Margaret S Beer; A J Noble; D N Middlemiss; L L Iversen; P Whiting
Molecular cloning of a serotonin receptor from human brain (5HT1E): a fifth 5HT1-like subtype.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(12):5517-21.
1992: George McAllister; P Whiting; E A Hammond; M R Knowles; John R Atack; F J Bailey; R Maigetter; C Ian Ragan
cDNA cloning of human and rat brain myo-inositol monophosphatase. Expression and characterization of the human recombinant enzyme.
The Biochemical journal 1992;284 ( Pt 3)():749-54.
1991: N S Gee; M R Knowles; George McAllister; C Ian Ragan
The effects of substrates, products and other ligands on the susceptibility of inositol monophosphatase to proteolysis by endoprotease lys-C.
FEBS letters 1991;284(1):95-7.