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Angela McCahill

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Nicole M Kane; Ruifang Lu; Ruth M Mackenzie; Angela McCahill; John McClure; Marco Meloni; Graeme Milligan; joanne mountford; Christopher Breen; Christian Delles; Betty Descamps; Costanza Emanueli; Lynsey Howard; Andrew H Baker
Role of microRNAs 99b, 181a, and 181b in the differentiation of human embryonic stem cells to vascular endothelial cells.
Peter Burton; David R Adams; Achamma Abraham; Robert W Allcock; Zhong Jiang; Angela McCahill; Jane Gilmour; John McAbney; Alexandra Kaupisch; Nicole Kane; George S Baillie; Andrew H Baker; Graeme Milligan; Miles D Houslay; joanne mountford
Erythro-9-(2-hydroxy-3-nonyl)adenine (EHNA) blocks differentiation and maintains the expression of pluripotency markers in human embryonic stem cells.
Peter Burton; David R Adams; Achamma Abraham; Robert W Allcock; Zhong Jiang; Angela McCahill; Jane Gilmour; John McAbney; Nicole Kane; George S Baillie; Fergus R McKenzie; Andrew H Baker; Miles D Houslay; joanne mountford; Graeme Milligan
Identification and characterization of small-molecule ligands that maintain pluripotency of human embryonic stem cells.

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All Publications

2012: Nicole M Kane; Ruifang Lu; Ruth M Mackenzie; Angela McCahill; John McClure; Marco Meloni; Graeme Milligan; joanne mountford; Christopher Breen; Christian Delles; Betty Descamps; Costanza Emanueli; Lynsey Howard; Andrew H Baker
Role of microRNAs 99b, 181a, and 181b in the differentiation of human embryonic stem cells to vascular endothelial cells.
Stem cells (Dayton, Ohio) 2012;30(4):643-54.
2010: Peter Burton; David R Adams; Achamma Abraham; Robert W Allcock; Zhong Jiang; Angela McCahill; Jane Gilmour; John McAbney; Alexandra Kaupisch; Nicole Kane; George S Baillie; Andrew H Baker; Graeme Milligan; Miles D Houslay; joanne mountford
Erythro-9-(2-hydroxy-3-nonyl)adenine (EHNA) blocks differentiation and maintains the expression of pluripotency markers in human embryonic stem cells.
The Biochemical journal 2010;432(3):575-84.
2010: Peter Burton; David R Adams; Achamma Abraham; Robert W Allcock; Zhong Jiang; Angela McCahill; Jane Gilmour; John McAbney; Nicole Kane; George S Baillie; Fergus R McKenzie; Andrew H Baker; Miles D Houslay; joanne mountford; Graeme Milligan
Identification and characterization of small-molecule ligands that maintain pluripotency of human embryonic stem cells.
Biochemical Society transactions 2010;38(4):1058-61.
2008: Angela McCahill; Lachlan Campbell; Theresa McSorley; Arvind Sood; Martin J Lynch; Xiang Li; Chen Yan; George S Baillie; Miles D Houslay
In cardiac myocytes, cAMP elevation triggers the down-regulation of transcripts and promoter activity for cyclic AMP phosphodiesterase-4A10 (PDE4A10).
Cellular signalling 2008;20(11):2071-83.
2007: K John Smith; George S Baillie; Eva I Hyde; Xiang Li; Thomas M Houslay; Angela McCahill; Allan J Dunlop; Graeme B Bolger; Enno Klussmann; David R Adams; Miles D Houslay
1H NMR structural and functional characterisation of a cAMP-specific phosphodiesterase-4D5 (PDE4D5) N-terminal region peptide that disrupts PDE4D5 interaction with the signalling scaffold proteins, beta-arrestin and RACK1.
Cellular signalling 2007;19(12):2612-24.
2006: Graeme B Bolger; George S Baillie; Xiang Li; Martin J Lynch; Pawel Herzyk; Ahmed Mohamed; Lisa High Mitchell; Angela McCahill; Christian Hundsrucker; Enno Klussmann; David R Adams; Miles D Houslay
Scanning peptide array analyses identify overlapping binding sites for the signalling scaffold proteins, beta-arrestin and RACK1, in cAMP-specific phosphodiesterase PDE4D5.
The Biochemical journal 2006;398(1):23-36.
2005: Angela McCahill; Theresa McSorley; Elaine Huston; Elaine V Hill; Martin J Lynch; Irene Gall; Guy Keryer; Birgitte Lygren; Kjetil Tasken; Gino van Heeke; Miles D Houslay
In resting COS1 cells a dominant negative approach shows that specific, anchored PDE4 cAMP phosphodiesterase isoforms gate the activation, by basal cyclic AMP production, of AKAP-tethered protein kinase A type II located in the centrosomal region.
Cellular signalling 2005;17(9):1158-73.
2003: Graeme B Bolger; Angela McCahill; Elaine Huston; York-Fong Cheung; Theresa McSorley; George S Baillie; Miles D Houslay
The unique amino-terminal region of the PDE4D5 cAMP phosphodiesterase isoform confers preferential interaction with beta-arrestins.
The Journal of biological chemistry 2003;278(49):49230-8.
2002: Angela McCahill; Jim Warwicker; Graeme B Bolger; Miles D Houslay; Stephen J Yarwood
The RACK1 scaffold protein: a dynamic cog in cell response mechanisms.
Molecular pharmacology 2002;62(6):1261-73.
2002: Graeme B Bolger; Angela McCahill; Stephen J Yarwood; Michael R Steele; Jim Warwicker; Miles D Houslay
Delineation of RAID1, the RACK1 interaction domain located within the unique N-terminal region of the cAMP-specific phosphodiesterase, PDE4D5.
BMC biochemistry 2002;3():24.
2001: Michael R Steele; Angela McCahill; D S Thompson; Carolynn MacKenzie; N W Isaacs; Miles D Houslay; Graeme B Bolger
Identification of a surface on the beta-propeller protein RACK1 that interacts with the cAMP-specific phosphodiesterase PDE4D5.
Cellular signalling 2001;13(7):507-13.
2000: Angela McCahill; D J Lankester; B S Park; Nigel T Price; Victor A Zammit
Acute modulation of the extent of apoB mRNA editing and the relative rates of syntheses of apoB48 and apoB100 in cultured rat hepatocytes by osmotic and other stress stimuli.
Molecular and cellular biochemistry 2000;208(1-2):77-87.