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Fiona McCann

Research Profile

Anatomy

Chemicals & Drugs

Living Beings

Disorders

Experimental Arthritis

Physiology

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Publications

TOP 3
Andrew C Palfreeman; Kay E McNamee; Fiona E McCann
New developments in the management of psoriasis and psoriatic arthritis: a focus on apremilast.
Anna K Andersson; Henrik Agersø; David Ahern; Parisa Amjadi; Chiwen Chang; Eugene Eyo Akujuru; Claus Haase; Fiona E McCann; Kay McNamee; Vibeke W Stennicke; Percy F Sumariwalla; Ditte Tornehave; John Trowsdale; Birgitte Uraø; Fionula M Brennan
Blockade of NKG2D ameliorates disease in mice with collagen-induced arthritis: a potential pathogenic role in chronic inflammatory arthritis.
Fiona E McCann; Andrew C Palfreeman; Melanie Andrews; Dany P Perocheau; Julia J Inglis; Peter Schafer; Eugene Eyo Akujuru; Richard O Williams; Fionula M Brennan
Apremilast, a novel PDE4 inhibitor, inhibits spontaneous production of tumour necrosis factor-alpha from human rheumatoid synovial cells and ameliorates experimental arthritis.

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All Publications

2013: Andrew C Palfreeman; Kay E McNamee; Fiona E McCann
New developments in the management of psoriasis and psoriatic arthritis: a focus on apremilast.
Drug design, development and therapy 2013;7():201-10.
2011: Anna K Andersson; Henrik Agersø; David Ahern; Parisa Amjadi; Chiwen Chang; Eugene Eyo Akujuru; Claus Haase; Fiona E McCann; Kay McNamee; Vibeke W Stennicke; Percy F Sumariwalla; Ditte Tornehave; John Trowsdale; Birgitte Uraø; Fionula M Brennan
Blockade of NKG2D ameliorates disease in mice with collagen-induced arthritis: a potential pathogenic role in chronic inflammatory arthritis.
Arthritis and rheumatism 2011;63(9):2617-29.
2010: Fiona E McCann; Andrew C Palfreeman; Melanie Andrews; Dany P Perocheau; Julia J Inglis; Peter Schafer; Eugene Eyo Akujuru; Richard O Williams; Fionula M Brennan
Apremilast, a novel PDE4 inhibitor, inhibits spontaneous production of tumour necrosis factor-alpha from human rheumatoid synovial cells and ameliorates experimental arthritis.
Arthritis research & therapy 2010;12(3):R107.
2010: Clare A Notley; Fiona E McCann; Julia J Inglis; Richard O Williams
ANTI-CD3 therapy expands the numbers of CD4+ and CD8+ Treg cells and induces sustained amelioration of collagen-induced arthritis.
Arthritis and rheumatism 2010;62(1):171-8.
2008: Clare A Notley; Julia J Inglis; Saba Alzabin; Fiona E McCann; Kay E McNamee; Richard O Williams
Blockade of tumor necrosis factor in collagen-induced arthritis reveals a novel immunoregulatory pathway for Th1 and Th17 cells.
The Journal of experimental medicine 2008;205(11):2491-7.
2008: Julia J Inglis; Egle Simelyte; Fiona E McCann; Gabriel Criado; Richard O Williams
Protocol for the induction of arthritis in C57BL/6 mice.
Nature protocols 2008;3(4):612-8.
2007: Geoffrey S Williams; Lucy M Collinson; Joanna Brzostek; Philipp Eissmann; Catarina Almeida; Fiona E McCann; Deborah N Burshtyn; Daniel M Davis
Membranous structures transfer cell surface proteins across NK cell immune synapses.
Traffic (Copenhagen, Denmark) 2007;8(9):1190-204.
2007: Johanna Endt; Fiona E McCann; Catarina Almeida; Doris Urlaub; Rufina Leung; Daniela Pende; Daniel M Davis; Carsten Watzl
Inhibitory receptor signals suppress ligation-induced recruitment of NKG2D to GM1-rich membrane domains at the human NK cell immune synapse.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(9):5606-11.
2007: Fiona E McCann; Philipp Eissmann; Björn Onfelt; Rufina Leung; Daniel M Davis
The activating NKG2D ligand MHC class I-related chain A transfers from target cells to NK cells in a manner that allows functional consequences.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(6):3418-26.
2004: Hongyan Wang; Fiona E McCann; John D Gordan; Xiang Wu; Monika Raab; Talat H Malik; Daniel M Davis; Christopher E Rudd
ADAP-SLP-76 binding differentially regulates supramolecular activation cluster (SMAC) formation relative to T cell-APC conjugation.
The Journal of experimental medicine 2004;200(8):1063-74.
2004: Sabrina B Taner; Björn Onfelt; Niina J Pirinen; Fiona E McCann; Anthony I Magee; Daniel M Davis
Control of immune responses by trafficking cell surface proteins, vesicles and lipid rafts to and from the immunological synapse.
Traffic (Copenhagen, Denmark) 2004;5(9):651-61.
2004: Konstantina Eleme; Sabrina B Taner; Björn Onfelt; Lucy M Collinson; Fiona E McCann; N Jan Chalupny; David Cosman; Colin Hopkins; Anthony I Magee; Daniel M Davis
Cell surface organization of stress-inducible proteins ULBP and MICA that stimulate human NK cells and T cells via NKG2D.
The Journal of experimental medicine 2004;199(7):1005-10.
2003: Daniel M Davis; Tadahiko Igakura; Fiona E McCann; Leo M Carlin; Katja Andersson; Bruno Vanherberghen; Anna Sjöström; Charles R M Bangham; Petter Höglund
The protean immune cell synapse: a supramolecular structure with many functions.
Seminars in immunology 2003;15(6):317-24.
2003: Fiona E McCann; Bruno Vanherberghen; Konstantina Eleme; Leo M Carlin; Ray J Newsam; David Goulding; Daniel M Davis
The size of the synaptic cleft and distinct distributions of filamentous actin, ezrin, CD43, and CD45 at activating and inhibitory human NK cell immune synapses.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(6):2862-70.
2002: Fiona E McCann; Klaus Suhling; Leo M Carlin; Konstantina Eleme; Sabrina B Taner; Kumiko Yanagi; Bruno Vanherberghen; Paul M W French; Daniel M Davis
Imaging immune surveillance by T cells and NK cells.
Immunological reviews 2002;189():179-92.
2001: Leo M Carlin; Konstantina Eleme; Fiona E McCann; Daniel M Davis
Intercellular transfer and supramolecular organization of human leukocyte antigen C at inhibitory natural killer cell immune synapses.
The Journal of experimental medicine 2001;194(10):1507-17.