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David Baulcombe
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8
Voinnet, Olivier
7
Angell, Susan
7
Peart, Jack
6
Bendahmane, Abdelhafid
5
Mestre, Pere
5
Jones, Louise
5
Malcuit, Isabelle
4
Lu, Rui
4
Moffett, Peter
4
Schwach, Frank
4
Brigneti, Gianinna
4
Dalmay, T
4
Studholme, David
4
Mosher, Rebecca
3
Kanyuka, Kostya
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All Publications
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2009: Mosher Rebecca A; Melnyk Charles W; Kelly Krystyna A; Dunn Ruth M; Studholme David J; Baulcombe David C
Uniparental expression of PolIV-dependent siRNAs in developing endosperm of Arabidopsis.
Nature 2009;460(7252):283-6.
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2009: Huang Linfeng; Jones Alexandra M E; Searle Iain; Patel Kanu; Vogler Hannes; Hubner Nina C; Baulcombe David C
An atypical RNA polymerase involved in RNA silencing shares small subunits with RNA polymerase II.
Nature structural & molecular biology 2009;16(1):91-3.
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2008: Preuss Sasha B; Costa-Nunes Pedro; Tucker Sarah; Pontes Olga; Lawrence Richard J; Mosher Rebecca; Kasschau Kristin D; Carrington James C; Baulcombe David C; Viegas Wanda; Pikaard Craig S
Multimegabase silencing in nucleolar dominance involves siRNA-directed DNA methylation and specific methylcytosine-binding proteins.
Molecular cell 2008;32(5):673-84.
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2008: Martín-Hernández Ana M; Baulcombe David C
Tobacco rattle virus 16-kilodalton protein encodes a suppressor of RNA silencing that allows transient viral entry in meristems.
Journal of virology 2008;82(8):4064-71.
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2008: Buhtz Anja; Springer Franziska; Chappell Louise; Baulcombe David C; Kehr Julia
Identification and characterization of small RNAs from the phloem of Brassica napus.
The Plant journal : for cell and molecular biology 2008;53(5):739-49.
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2008: Mosher Rebecca A; Schwach Frank; Studholme David; Baulcombe David C
PolIVb influences RNA-directed DNA methylation independently of its role in siRNA biogenesis.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(8):3145-50.
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2007: Smith Lisa M; Baulcombe David C
Dissection of silencing signal movement in Arabidopsis.
Plant signaling & behavior 2007;2(6):501-2.
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2007: Bäurle Isabel; Smith Lisa; Baulcombe David C; Dean Caroline
Widespread role for the flowering-time regulators FCA and FPA in RNA-mediated chromatin silencing.
Science (New York, N.Y.) 2007;318(5847):109-12.
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2007: Baumberger Nicolas; Tsai Ching-Hsui; Lie Miranda; Havecker Ericka; Baulcombe David C
The Polerovirus silencing suppressor P0 targets ARGONAUTE proteins for degradation.
Current biology : CB 2007;17(18):1609-14.
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2007: Molnár Attila; Schwach Frank; Studholme David J; Thuenemann Eva C; Baulcombe David C
miRNAs control gene expression in the single-cell alga Chlamydomonas reinhardtii.
Nature 2007;447(7148):1126-9.
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2007: Tameling Wladimir I L; Baulcombe David C
Physical association of the NB-LRR resistance protein Rx with a Ran GTPase-activating protein is required for extreme resistance to Potato virus X.
The Plant cell 2007;19(5):1682-94.
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2007: Smith Lisa M; Pontes Olga; Searle Iain; Yelina Nataliya; Yousafzai Faridoon K; Herr Alan J; Pikaard Craig S; Baulcombe David C
An SNF2 protein associated with nuclear RNA silencing and the spread of a silencing signal between cells in Arabidopsis.
The Plant cell 2007;19(5):1507-21.
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2007: Hernandez-Pinzon Inmaculada; Yelina Nataliya E; Schwach Frank; Studholme David J; Baulcombe David; Dalmay Tamas
SDE5, the putative homologue of a human mRNA export factor, is required for transgene silencing and accumulation of trans-acting endogenous siRNA.
The Plant journal : for cell and molecular biology 2007;50(1):140-8.
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2007: Baulcombe David
David Baulcombe.
Current biology : CB 2007;17(3):R73-4.
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2007: Baulcombe David C
Molecular biology. Amplified silencing.
Science (New York, N.Y.) 2007;315(5809):199-200.
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2007: Searle Iain R; Mosher Rebecca A; Melnyk Charles W; Baulcombe David C
Small RNAs hit the big time.
The New phytologist 2007;174(3):479-82.
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2006: Farnham Garry; Baulcombe David C
Artificial evolution extends the spectrum of viruses that are targeted by a disease-resistance gene from potato.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(49):18828-33.
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2006: Talmor-Neiman Mali; Stav Ran; Klipcan Liron; Buxdorf Kobi; Baulcombe David C; Arazi Tzahi
Identification of trans-acting siRNAs in moss and an RNA-dependent RNA polymerase required for their biogenesis.
The Plant journal : for cell and molecular biology 2006;48(4):511-21.
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2006: Herr Alan J; Molnàr Attila; Jones Alex; Baulcombe David C
Defective RNA processing enhances RNA silencing and influences flowering of Arabidopsis.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(41):14994-5001.
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2006: Matousek Jaroslav; Vrba Lukás; Skopek Josef; Orctova Lidmila; Pesina Karel; Heyerick Arne; Baulcombe David; De Keukeleire Denis
Sequence analysis of a "true" chalcone synthase (chs_H1) oligofamily from hop (Humulus lupulus L.) and PAP1 activation of chs_H1 in heterologous systems.
Journal of agricultural and food chemistry 2006;54(20):7606-15.
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2006: Mestre Pere; Baulcombe David C
Elicitor-mediated oligomerization of the tobacco N disease resistance protein.
The Plant cell 2006;18(2):491-501.
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2005: Bayne Elizabeth H; Rakitina Daria V; Morozov Sergey Y; Baulcombe David C
Cell-to-cell movement of potato potexvirus X is dependent on suppression of RNA silencing.
The Plant journal : for cell and molecular biology 2005;44(3):471-82.
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2005: Arazi Tzahi; Talmor-Neiman Mali; Stav Ran; Riese Maike; Huijser Peter; Baulcombe David C
Cloning and characterization of micro-RNAs from moss.
The Plant journal : for cell and molecular biology 2005;43(6):837-48.
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2005: Baumberger N; Baulcombe D C
Arabidopsis ARGONAUTE1 is an RNA Slicer that selectively recruits microRNAs and short interfering RNAs.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(33):11928-33.
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2005: Schwach Frank; Vaistij Fabian E; Jones Louise; Baulcombe David C
An RNA-dependent RNA polymerase prevents meristem invasion by potato virus X and is required for the activity but not the production of a systemic silencing signal.
Plant physiology 2005;138(4):1842-52.
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2005: Baulcombe David
RNA silencing.
Trends in biochemical sciences 2005;30(6):290-3.
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2005: Peart Jack R; Mestre Pere; Lu Rui; Malcuit Isabelle; Baulcombe David C
NRG1, a CC-NB-LRR protein, together with N, a TIR-NB-LRR protein, mediates resistance against tobacco mosaic virus.
Current biology : CB 2005;15(10):968-73.
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2005: Herr A J; Jensen M B; Dalmay T; Baulcombe D C
RNA polymerase IV directs silencing of endogenous DNA.
Science (New York, N.Y.) 2005;308(5718):118-20.
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2004: Baulcombe David
RNA silencing in plants.
Nature 2004;431(7006):356-63.
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2004: Achard Patrick; Herr Alan; Baulcombe David C; Harberd Nicholas P
Modulation of floral development by a gibberellin-regulated microRNA.
Development (Cambridge, England) 2004;131(14):3357-65.
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2004: Brigneti Gianinna; Martín-Hernández Ana M; Jin Hailing; Chen Judy; Baulcombe David C; Baker Barbara; Jones Jonathan D G
Virus-induced gene silencing in Solanum species.
The Plant journal : for cell and molecular biology 2004;39(2):264-72.
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2004: Baulcombe David C; Molnár Attila
Crystal structure of p19--a universal suppressor of RNA silencing.
Trends in biochemical sciences 2004;29(6):279-81.
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2004: Schornack Sebastian; Ballvora Agim; Gürlebeck Doreen; Peart Jack; Baulcombe David; Ganal Martin; Baker Barbara; Bonas Ulla; Lahaye Thomas
The tomato resistance protein Bs4 is a predicted non-nuclear TIR-NB-LRR protein that mediates defense responses to severely truncated derivatives of AvrBs4 and overexpressed AvrBs3.
The Plant journal : for cell and molecular biology 2004;37(1):46-60.
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2003: Mestre Pere; Brigneti Gianinna; Durrant Marcus C; Baulcombe David C
Potato virus Y NIa protease activity is not sufficient for elicitation of Ry-mediated disease resistance in potato.
The Plant journal : for cell and molecular biology 2003;36(6):755-61.
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2003: Lu Rui; Malcuit Isabelle; Moffett Peter; Ruiz Maria T; Peart Jack; Wu Ai-Jiuan; Rathjen John P; Bendahmane Abdelhafid; Day Louise; Baulcombe David C
High throughput virus-induced gene silencing implicates heat shock protein 90 in plant disease resistance.
The EMBO journal 2003;22(21):5690-9.
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2003: Lu Rui; Martin-Hernandez Ana Montserrat; Peart Jack R; Malcuit Isabelle; Baulcombe David C
Virus-induced gene silencing in plants.
Methods (San Diego, Calif.) 2003;30(4):296-303.
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2003: Voinnet Olivier; Rivas Susana; Mestre Pere; Baulcombe David
An enhanced transient expression system in plants based on suppression of gene silencing by the p19 protein of tomato bushy stunt virus.
The Plant journal : for cell and molecular biology 2003;33(5):949-56.
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2002: Bendahmane Abdelhafid; Farnham Garry; Moffett Peter; Baulcombe David C
Constitutive gain-of-function mutants in a nucleotide binding site-leucine rich repeat protein encoded at the Rx locus of potato.
The Plant journal : for cell and molecular biology 2002;32(2):195-204.
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2002: Baulcombe David
DNA events. An RNA microcosm.
Science (New York, N.Y.) 2002;297(5589):2002-3.
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2002: Hamilton Andrew; Voinnet Olivier; Chappell Louise; Baulcombe David
Two classes of short interfering RNA in RNA silencing.
The EMBO journal 2002;21(17):4671-9.
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2002: Moffett Peter; Farnham Garry; Peart Jack; Baulcombe David C
Interaction between domains of a plant NBS-LRR protein in disease resistance-related cell death.
The EMBO journal 2002;21(17):4511-9.
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2002: Bouarab K; Melton R; Peart J; Baulcombe D; Osbourn A
A saponin-detoxifying enzyme mediates suppression of plant defences.
Nature 2002;418(6900):889-92.
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2002: Peart Jack R; Lu Rui; Sadanandom Ari; Malcuit Isabelle; Moffett Peter; Brice David C; Schauser Leif; Jaggard Daniel A W; Xiao Shunyuan; Coleman Mark J; Dow Max; Jones Jonathan D G; Shirasu Ken; Baulcombe David C
Ubiquitin ligase-associated protein SGT1 is required for host and nonhost disease resistance in plants.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(16):10865-9.
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2002: Baulcombe David
Viral suppression of systemic silencing.
Trends in microbiology 2002;10(7):306-8.
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2002: Mallory Allison C; Parks Graham; Endres Matthew W; Baulcombe David; Bowman Lewis H; Pruss Gail J; Vance Vicki B
The amplicon-plus system for high-level expression of transgenes in plants.
Nature biotechnology 2002;20(6):622-5.
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2002: Abbink Truus E M; Peart Jack R; Mos Thera N M; Baulcombe David C; Bol John F; Linthorst Huub J M
Silencing of a gene encoding a protein component of the oxygen-evolving complex of photosystem II enhances virus replication in plants.
Virology 2002;295(2):307-19.
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2002: Vaistij Fabián E; Jones Louise; Baulcombe David C
Spreading of RNA targeting and DNA methylation in RNA silencing requires transcription of the target gene and a putative RNA-dependent RNA polymerase.
The Plant cell 2002;14(4):857-67.
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2002: Peart Jack R; Cook Graeme; Feys Bart J; Parker Jane E; Baulcombe David C
An EDS1 orthologue is required for N-mediated resistance against tobacco mosaic virus.
The Plant journal : for cell and molecular biology 2002;29(5):569-79.
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2002: Baulcombe David
RNA silencing.
Current biology : CB 2002;12(3):R82-4.
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2001: Jones L; Ratcliff F; Baulcombe D C
RNA-directed transcriptional gene silencing in plants can be inherited independently of the RNA trigger and requires Met1 for maintenance.
Current biology : CB 2001;11(10):747-57.
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2001: Dalmay T; Horsefield R; Braunstein T H; Baulcombe D C
SDE3 encodes an RNA helicase required for post-transcriptional gene silencing in Arabidopsis.
The EMBO journal 2001;20(8):2069-78.
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2001: Thomas C L; Jones L; Baulcombe D C; Maule A J
Size constraints for targeting post-transcriptional gene silencing and for RNA-directed methylation in Nicotiana benthamiana using a potato virus X vector.
The Plant journal : for cell and molecular biology 2001;25(4):417-25.
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2001: Ratcliff F; Martin-Hernandez A M; Baulcombe D C
Technical Advance. Tobacco rattle virus as a vector for analysis of gene function by silencing.
The Plant journal : for cell and molecular biology 2001;25(2):237-45.
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2000: Baulcombe D C
Molecular biology. Unwinding RNA silencing.
Science (New York, N.Y.) 2000;290(5494):1108-9.
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2000: Voinnet O; Lederer C; Baulcombe D C
A viral movement protein prevents spread of the gene silencing signal in Nicotiana benthamiana.
Cell 2000;103(1):157-67.
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2000: Mestre P; Brigneti G; Baulcombe D C
An Ry-mediated resistance response in potato requires the intact active site of the NIa proteinase from potato virus Y.
The Plant journal : for cell and molecular biology 2000;23(5):653-61.
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2000: van der Vossen E A; van der Voort J N; Kanyuka K; Bendahmane A; Sandbrink H; Baulcombe D C; Bakker J; Stiekema W J; Klein-Lankhorst R M
Homologues of a single resistance-gene cluster in potato confer resistance to distinct pathogens: a virus and a nematode.
The Plant journal : for cell and molecular biology 2000;23(5):567-76.
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2000: Yang Y; Ding B; Baulcombe D C; Verchot J
Cell-to-cell movement of the 25K protein of potato virus X is regulated by three other viral proteins.
Molecular plant-microbe interactions : MPMI 2000;13(6):599-605.
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2000: Dalmay T; Hamilton A; Rudd S; Angell S; Baulcombe D C
An RNA-dependent RNA polymerase gene in Arabidopsis is required for posttranscriptional gene silencing mediated by a transgene but not by a virus.
Cell 2000;101(5):543-53.
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2000: Dalmay T; Hamilton A; Mueller E; Baulcombe D C
Potato virus X amplicons in arabidopsis mediate genetic and epigenetic gene silencing.
The Plant cell 2000;12(3):369-79.
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2000: Bendahmane A; Querci M; Kanyuka K; Baulcombe D C
Agrobacterium transient expression system as a tool for the isolation of disease resistance genes: application to the Rx2 locus in potato.
The Plant journal : for cell and molecular biology 2000;21(1):73-81.
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2000: Malcuit I; de Jong W; Baulcombe D C; Shields D C; Kavanagh T A
Acquisition of multiple virulence/avirulence determinants by potato virus X (PVX) has occurred through convergent evolution rather than through recombination.
Virus genes 2000;20(2):165-72.
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1999: Jones L; Hamilton A J; Voinnet O; Thomas C L; Maule A J; Baulcombe D C
RNA-DNA interactions and DNA methylation in post-transcriptional gene silencing.
The Plant cell 1999;11(12):2291-301.
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1999: Angell S M; Baulcombe D C
Technical advance: potato virus X amplicon-mediated silencing of nuclear genes.
The Plant journal : for cell and molecular biology 1999;20(3):357-62.
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1999: Voinnet O; Pinto Y M; Baulcombe D C
Suppression of gene silencing: a general strategy used by diverse DNA and RNA viruses of plants.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(24):14147-52.
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1999: Hamilton A J; Baulcombe D C
A species of small antisense RNA in posttranscriptional gene silencing in plants.
Science (New York, N.Y.) 1999;286(5441):950-2.
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1999: Baulcombe D C
Gene silencing: RNA makes RNA makes no protein.
Current biology : CB 1999;9(16):R599-601.
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1999: Pinto Y M; Kok R A; Baulcombe D C
Resistance to rice yellow mottle virus (RYMV) in cultivated African rice varieties containing RYMV transgenes.
Nature biotechnology 1999;17(7):702-7.
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1999: Bendahmane A; Kanyuka K; Baulcombe D C
The Rx gene from potato controls separate virus resistance and cell death responses.
The Plant cell 1999;11(5):781-92.
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1999: Baulcombe D C
Fast forward genetics based on virus-induced gene silencing.
Current opinion in plant biology 1999;2(2):109-13.
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1999: Baulcombe D
Viruses and gene silencing in plants.
Archives of virology. Supplementum 1999;15():189-201.
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1998: Brigneti G; Voinnet O; Li W X; Ji L H; Ding S W; Baulcombe D C
Viral pathogenicity determinants are suppressors of transgene silencing in Nicotiana benthamiana.
The EMBO journal 1998;17(22):6739-46.
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1998: Voinnet O; Vain P; Angell S; Baulcombe D C
Systemic spread of sequence-specific transgene RNA degradation in plants is initiated by localized introduction of ectopic promoterless DNA.
Cell 1998;95(2):177-87.
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1998: Verchot J; Angell S M; Baulcombe D C
In vivo translation of the triple gene block of potato virus X requires two subgenomic mRNAs.
Journal of virology 1998;72(10):8316-20.
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1997: Jakab G; Droz E; Brigneti G; Baulcombe D; Malnoë P
Infectious in vivo and in vitro transcripts from a full-length cDNA clone of PVY-N605, a Swiss necrotic isolate of potato virus Y.
The Journal of general virology 1997;78 ( Pt 12)():3141-5.
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1997: Voinnet O; Baulcombe D C
Systemic signalling in gene silencing.
Nature 1997;389(6651):553.
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1997: Spillane C; Verchot J; Kavanagh T A; Baulcombe D C
Concurrent suppression of virus replication and rescue of movement-defective virus in transgenic plants expressing the coat protein of potato virus X.
Virology 1997;236(1):76-84.
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1997: Ratcliff F; Harrison B D; Baulcombe D C
A similarity between viral defense and gene silencing in plants.
Science (New York, N.Y.) 1997;276(5318):1558-60.
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1997: Angell S M; Baulcombe D C
Consistent gene silencing in transgenic plants expressing a replicating potato virus X RNA.
The EMBO journal 1997;16(12):3675-84.
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1997: Davenport G F; Baulcombe D C
Mutation of the GKS motif of the RNA-dependent RNA polymerase from potato virus X disables or eliminates virus replication.
The Journal of general virology 1997;78 ( Pt 6)():1247-51.
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1996: Baulcombe D C
RNA as a target and an initiator of post-transcriptional gene silencing in transgenic plants.
Plant molecular biology 1996;32(1-2):79-88.
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1996: Angell S M; Davies C; Baulcombe D C
Cell-to-cell movement of potato virus X is associated with a change in the size-exclusion limit of plasmodesmata in trichome cells of Nicotiana clevelandii.
Virology 1996;216(1):197-201.
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1995: Bendahmane A; Köhn B A; Dedi C; Baulcombe D C
The coat protein of potato virus X is a strain-specific elicitor of Rx1-mediated virus resistance in potato.
The Plant journal : for cell and molecular biology 1995;8(6):933-41.
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1995: Santa Cruz S; Baulcombe D
Analysis of potato virus X coat protein genes in relation to resistance conferred by the genes Nx, Nb and Rx1 of potato.
The Journal of general virology 1995;76 ( Pt 8)():2057-61.
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1995: Sablowski R W; Baulcombe D C; Bevan M
Expression of a flower-specific Myb protein in leaf cells using a viral vector causes ectopic activation of a target promoter.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(15):6901-5.
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1995: Baulcombe D C; Chapman S; Santa Cruz S
Jellyfish green fluorescent protein as a reporter for virus infections.
The Plant journal : for cell and molecular biology 1995;7(6):1045-53.
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1995: Angell S M; Baulcombe D C
Cell-to-cell movement of potato virus X revealed by micro-injection of a viral vector tagged with the beta-glucuronidase gene.
The Plant journal : for cell and molecular biology 1995;7(1):135-40.
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1994: Baulcombe D; Gilbert J; Goulden M; Köhm B; Cruz S S
Molecular biology of resistance to potato virus X in potato.
Biochemical Society symposium 1994;60():207-18.
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1993: Goulden M G; Köhm B A; Santa Cruz S; Kavanagh T A; Baulcombe D C
A feature of the coat protein of potato virus X affects both induced virus resistance in potato and viral fitness.
Virology 1993;197(1):293-302.
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1993: Davies C; Hills G; Baulcombe D C
Sub-cellular localization of the 25-kDa protein encoded in the triple gene block of potato virus X.
Virology 1993;197(1):166-75.
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1993: Cruz S S; Baulcombe D C
Molecular analysis of potato virus X isolates in relation to the potato hypersensitivity gene Nx.
Molecular plant-microbe interactions : MPMI 1993;6(6):707-14.
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1993: Baulcombe D C; Lloyd J; Manoussopoulos I N; Roberts I M; Harrison B D
Signal for potyvirus-dependent aphid transmission of potato aucuba mosaic virus and the effect of its transfer to potato virus X.
The Journal of general virology 1993;74 ( Pt 7)():1245-53.
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1993: Boccard F; Baulcombe D
Mutational analysis of cis-acting sequences and gene function in RNA3 of cucumber mosaic virus.
Virology 1993;193(2):563-78.
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1993: Longstaff M; Brigneti G; Boccard F; Chapman S; Baulcombe D
Extreme resistance to potato virus X infection in plants expressing a modified component of the putative viral replicase.
The EMBO journal 1993;12(2):379-86.
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1992: Cejudo F J; Ghose T K; Stabel P; Baulcombe D C
Analysis of the gibberellin-responsive promoter of a cathepsin B-like gene from wheat.
Plant molecular biology 1992;20(5):849-56.
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1992: Chapman S; Hills G; Watts J; Baulcombe D
Mutational analysis of the coat protein gene of potato virus X: effects on virion morphology and viral pathogenicity.
Virology 1992;191(1):223-30.
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1992: Cejudo F J; Murphy G; Chinoy C; Baulcombe D C
A gibberellin-regulated gene from wheat with sequence homology to cathepsin B of mammalian cells.
The Plant journal : for cell and molecular biology 1992;2(6):937-48.
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1992: Kavanagh T; Goulden M; Santa Cruz S; Chapman S; Barker I; Baulcombe D
Molecular analysis of a resistance-breaking strain of potato virus X.
Virology 1992;189(2):609-17.
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1992: Chapman S; Kavanagh T; Baulcombe D
Potato virus X as a vector for gene expression in plants.
The Plant journal : for cell and molecular biology 1992;2(4):549-57.
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1992: Boccard F; Baulcombe D C
Infectious in vitro transcripts from amplified cDNAs of the Y and Kin strains of cucumber mosaic virus.
Gene 1992;114(2):223-7.
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1991: Guilford P J; Ziegler-Graff V; Baulcombe D C
Mutation and replacement of the 16-kDa protein gene in RNA-1 of tobacco rattle virus.
Virology 1991;182(2):607-14.
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1991: Ziegler-Graff V; Guilford P J; Baulcombe D C
Tobacco rattle virus RNA-1 29K gene product potentiates viral movement and also affects symptom induction in tobacco.
Virology 1991;182(1):145-55.
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1990: Jaegle M; Devic M; Longstaff M; Baulcombe D
Cucumber mosaic virus satellite RNA (Y strain): analysis of sequences which affect yellow mosaic symptoms on tobacco.
The Journal of general virology 1990;71 ( Pt 9)():1905-12.
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1990: Devic M; Jaegle M; Baulcombe D
Cucumber mosaic virus satellite RNA (strain Y): analysis of sequences which affect systemic necrosis on tomato.
The Journal of general virology 1990;71 ( Pt 7)():1443-9.
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1989: Devic M; Jaegle M; Baulcombe D
Symptom production on tobacco and tomato is determined by two distinct domains of the satellite RNA of cucumber mosaic virus (strain Y).
The Journal of general virology 1989;70 ( Pt 10)():2765-74.
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