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Bruce Baum

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Anne M Rowzee; Changyu Zheng; Bruce J Baum; Sarah Krygowski; Paola J Perez-Riveros; Niamh X Cawley
Expression and secretion of human proinsulin-B10 from mouse salivary glands: implications for the treatment of type I diabetes mellitus.
Bruce J Baum; Jaime Brahim; Peter D Burbelo; Clara C Chen; John A Chiorini; Deborah E Citrin; Ana P Cotrim; Stamatina Danielides; Corinne M Goldsmith; Shuying Liu; Linda McCullagh; James B Mitchell; Nikolay P Nikolov; Liesl K Nottingham; Nicholas J Patronas; Susan F Rudy; R James Turner; Carter Van Waes; Millie A Whatley; Changyu Zheng; Ilias Alevizos; Gabor G Illei
Early responses to adenoviral-mediated transfer of the aquaporin-1 cDNA for radiation-induced salivary hypofunction.
Ana P Cotrim; James B Mitchell; Anastasia L Sowers; Abraham N Sunshine; Angela D Thetford; Masanobu Yoshikawa; Changyu Zheng; John A Cook; Bruce J Baum
Pharmacological protection from radiation ± cisplatin-induced oral mucositis.

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2013: Anne M Rowzee; Changyu Zheng; Bruce J Baum; Sarah Krygowski; Paola J Perez-Riveros; Niamh X Cawley
Expression and secretion of human proinsulin-B10 from mouse salivary glands: implications for the treatment of type I diabetes mellitus.
PloS one 2013;8(3):e59222.
2012: Bruce J Baum; Jaime Brahim; Peter D Burbelo; Clara C Chen; John A Chiorini; Deborah E Citrin; Ana P Cotrim; Stamatina Danielides; Corinne M Goldsmith; Shuying Liu; Linda McCullagh; James B Mitchell; Nikolay P Nikolov; Liesl K Nottingham; Nicholas J Patronas; Susan F Rudy; R James Turner; Carter Van Waes; Millie A Whatley; Changyu Zheng; Ilias Alevizos; Gabor G Illei
Early responses to adenoviral-mediated transfer of the aquaporin-1 cDNA for radiation-induced salivary hypofunction.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(47):19403-7.
2012: Ana P Cotrim; James B Mitchell; Anastasia L Sowers; Abraham N Sunshine; Angela D Thetford; Masanobu Yoshikawa; Changyu Zheng; John A Cook; Bruce J Baum
Pharmacological protection from radiation ± cisplatin-induced oral mucositis.
International journal of radiation oncology, biology, physics 2012;83(4):1284-90.
2012: Changyu Zheng; Ana P Cotrim; Fumi Mineshiba; Nikolay Nikolov; William D Swaim; Bruce J Baum
A novel hybrid adenoretroviral vector with more extensive E3 deletion extends transgene expression in submandibular glands.
Human gene therapy methods 2012;23(3):169-81.
2011: Yuval Samuni; Bruce J Baum
Gene delivery in salivary glands: from the bench to the clinic.
Biochimica et biophysica acta 2011;1812(11):1515-21.
2011: Changyu Zheng; Sandra Afione; Molly Boyle; John A Chiorini; Tim Clackson; Benjamin Goldstein; Richard D Irwin; Abraham Nyska; Victor M Rivera; Molly K Vallant; Antonis Voutetakis; Martin L Wenk; Bruce J Baum
Assessment of the safety and biodistribution of a regulated AAV2 gene transfer vector after delivery to murine submandibular glands.
Toxicological sciences : an official journal of the Society of Toxicology 2011;123(1):247-55.
2011: Simon D Tran; Robert S Redman; A John Barrett; Steven Z Pavletic; Sharon Key; Y Liu; Ashley Carpenter; Hieu M Nguyen; Yoshinori Sumita; Bruce J Baum; Stanley R Pillemer; Eva Mezey
Microchimerism in salivary glands after blood- and marrow-derived stem cell transplantation.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2011;17(3):429-33.
2011: Janik Adriaansen; P Perez; Changyu Zheng; Michael T Collins; Bruce J Baum
Human parathyroid hormone is secreted primarily into the bloodstream after rat parotid gland gene transfer.
Human gene therapy 2011;22(1):84-92.
2011: R Gao; X Yan; Changyu Zheng; Corinne M Goldsmith; Sandra Afione; B Hai; Jianguo Xu; Jing Zhou; Chunmei Zhang; John A Chiorini; Bruce J Baum; Shixuan Wang
AAV2-mediated transfer of the human aquaporin-1 cDNA restores fluid secretion from irradiated miniature pig parotid glands.
Gene therapy 2011;18(1):38-42.
2011: Changyu Zheng; T Shinomiya; Corinne M Goldsmith; Giovanni Di Pasquale; Bruce J Baum
Convenient and reproducible in vivo gene transfer to mouse parotid glands.
Oral diseases 2011;17(1):77-82.
2010: Junji Xu; Xing Yan; Runtao Gao; Lisha Mao; Ana P Cotrim; Changyu Zheng; Chunmei Zhang; Bruce J Baum; Songlin Wang
Effect of irradiation on microvascular endothelial cells of parotid glands in the miniature pig.
International journal of radiation oncology, biology, physics 2010;78(3):897-903.
2010: Paola Perez; Anne M Rowzee; Changyu Zheng; Janik Adriaansen; Bruce J Baum
Salivary epithelial cells: an unassuming target site for gene therapeutics.
The international journal of biochemistry & cell biology 2010;42(6):773-7.
2010: Changyu Zheng; Antonis Voutetakis; M Metzger; Sandra Afione; Ana P Cotrim; Michael Eckhaus; V M Rivera; Tim Clackson; John A Chiorini; R E Donahue; C E Dunbar; Bruce J Baum
Evaluation of a rapamycin-regulated serotype 2 adeno-associated viral vector in macaque parotid glands.
Oral diseases 2010;16(3):269-77.
2010: Bruce J Baum; Janik Adriaansen; Ana P Cotrim; Corinne M Goldsmith; Paola Perez; Senrong Qi; Anne M Rowzee; Changyu Zheng
Gene therapy of salivary diseases.
Methods in molecular biology (Clifton, N.J.) 2010;666():3-20.
2010: Janik Adriaansen; Changyu Zheng; Paola Perez; Bruce J Baum
Production and sorting of transgenic, modified human parathyroid hormone in vivo in rat salivary glands.
Biochemical and biophysical research communications 2010;391(1):768-72.
2010: Changyu Zheng; Nikolay P Nikolov; Ilias Alevizos; Ana P Cotrim; Shuying Liu; Linda McCullagh; John A Chiorini; Gabor G Illei; Bruce J Baum
Transient detection of E1-containing adenovirus in saliva after the delivery of a first-generation adenoviral vector to human parotid gland.
The journal of gene medicine 2010;12(1):3-10.
2010: Bruce J Baum; Changyu Zheng; Ilias Alevizos; Ana P Cotrim; Shuying Liu; Linda McCullagh; Corinne M Goldsmith; Nancy McDermott; John A Chiorini; Nikolay P Nikolov; Gabor G Illei
Development of a gene transfer-based treatment for radiation-induced salivary hypofunction.
Oral oncology 2010;46(1):4-8.
2010: Antonis Voutetakis; Changyu Zheng; Ana P Cotrim; Fumi Mineshiba; Sandra Afione; N Roescher; William D Swaim; M Metzger; Michael Eckhaus; R E Donahue; C E Dunbar; John A Chiorini; Bruce J Baum
AAV5-mediated gene transfer to the parotid glands of non-human primates.
Gene therapy 2010;17(1):50-60.
2009: Bruce J Baum
In vivo veritas: the power of in situ manipulation of cells in a living animal. Focus on "Expression of plasmid DNA in the salivary gland epithelium: novel approaches to study dynamic cellular processes in live animals".
American journal of physiology. Cell physiology 2009;297(6):C1333-5.
2009: Changyu Zheng; Ana P Cotrim; Abraham N Sunshine; Takayuki Sugito; Lina Liu; Anastasia Sowers; James B Mitchell; Bruce J Baum
Prevention of radiation-induced oral mucositis after adenoviral vector-mediated transfer of the keratinocyte growth factor cDNA to mouse submandibular glands.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(14):4641-8.
2009: Gabor Z Racz; Paola Perez-Riveros; Janik Adriaansen; Changyu Zheng; Bruce J Baum
In vivo secretion of the mouse immunoglobulin G Fc fragment from rat submandibular glands.
The journal of gene medicine 2009;11(7):580-7.
2009: Bo Hai; Xing Yan; Antonis Voutetakis; Changyu Zheng; Ana P Cotrim; Zhaochen Shan; Gang Ding; Chunmei Zhang; Junji Xu; Corinne M Goldsmith; Sandra Afione; John A Chiorini; Bruce J Baum; Songlin Wang
Long-term transduction of miniature pig parotid glands using serotype 2 adeno-associated viral vectors.
The journal of gene medicine 2009;11(6):506-14.
2008: Antonis Voutetakis; Changyu Zheng; Mark Metzger; Ana P Cotrim; Robert E Donahue; Cynthia E Dunbar; Bruce J Baum
Sorting of transgenic secretory proteins in rhesus macaque parotid glands after adenovirus-mediated gene transfer.
Human gene therapy 2008;19(12):1401-5.
2008: J Adriaansen; P Perez; Corinne M Goldsmith; Changyu Zheng; Bruce J Baum
Differential sorting of human parathyroid hormone after transduction of mouse and rat salivary glands.
Human gene therapy 2008;19(10):1021-8.
2008: Yuval Samuni; Changyu Zheng; Niamh X Cawley; Ana P Cotrim; Y Peng Loh; Bruce J Baum
Sorting of growth hormone-erythropoietin fusion proteins in rat salivary glands.
Biochemical and biophysical research communications 2008;373(1):136-9.
2008: Changyu Zheng; Joseph M Vitolo; Weitian Zhang; Fumi Mineshiba; John A Chiorini; Bruce J Baum
Extended transgene expression from a nonintegrating adenoviral vector containing retroviral elements.
Molecular therapy : the journal of the American Society of Gene Therapy 2008;16(6):1089-97.
2008: Yuval Samuni; Niamh X Cawley; Changyu Zheng; Ana P Cotrim; Y Peng Loh; Bruce J Baum
Sorting behavior of a transgenic erythropoietin-growth hormone fusion protein in murine salivary glands.
Human gene therapy 2008;19(3):279-86.
2008: Changyu Zheng; Bruce J Baum
Evaluation of promoters for use in tissue-specific gene delivery.
Methods in molecular biology (Clifton, N.J.) 2008;434():205-19.
2008: Ana P Cotrim; Bruce J Baum
Gene therapy: some history, applications, problems, and prospects.
Toxicologic pathology 2008;36(1):97-103.
2007: Ana P Cotrim; Anastasia L Sowers; James B Mitchell; Bruce J Baum
Prevention of irradiation-induced salivary hypofunction by microvessel protection in mouse salivary glands.
Molecular therapy : the journal of the American Society of Gene Therapy 2007;15(12):2101-6.
2007: Antonis Voutetakis; Changyu Zheng; Jianghua Wang; Corinne M Goldsmith; Sandra Afione; John A Chiorini; M L Wenk; Molly K Vallant; Richard D Irwin; Bruce J Baum
Gender differences in serotype 2 adeno-associated virus biodistribution after administration to rodent salivary glands.
Human gene therapy 2007;18(11):1109-18.
2007: Xing Yan; Antonis Voutetakis; Changyu Zheng; Bo Hai; Chunmei Zhang; Bruce J Baum; Songlin Wang
Sorting of transgenic secretory proteins in miniature pig parotid glands following adenoviral-mediated gene transfer.
The journal of gene medicine 2007;9(9):779-87.
2007: Ana P Cotrim; Fuminori Hyodo; Ken-Ichiro Matsumoto; Anastasia L Sowers; John A Cook; Bruce J Baum; Murali K Cherukuri; James B Mitchell
Differential radiation protection of salivary glands versus tumor by Tempol with accompanying tissue assessment of Tempol by magnetic resonance imaging.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(16):4928-33.
2007: Seshagiri R Nandula; Shoba Amarnath; Alfredo A Molinolo; Bidhan Bandyopadhyay; Bradford Hall; Corinne M Goldsmith; Changyu Zheng; Jonas Larsson; Taduru Sreenath; WanJun Chen; Indu S Ambudkar; Stefan Karlsson; Bruce J Baum; Ashok Kulkarni
Female mice are more susceptible to developing inflammatory disorders due to impaired transforming growth factor beta signaling in salivary glands.
Arthritis and rheumatism 2007;56(6):1798-805.
2007: Antonis Voutetakis; Changyu Zheng; Fumi Mineshiba; Ana P Cotrim; Corinne M Goldsmith; Michael Schmidt; Sandra Afione; Nienke Roescher; Mark Metzger; Michael Eckhaus; John A Chiorini; Cynthia E Dunbar; Robert E Donahue; Bruce J Baum
Adeno-associated virus serotype 2-mediated gene transfer to the parotid glands of nonhuman primates.
Human gene therapy 2007;18(2):142-50.
2007: Bruce J Baum
Inadequate training in the biological sciences and medicine for dental students: an impending crisis for dentistry.
Journal of the American Dental Association (1939) 2007;138(1):16, 18, 20 passim.
2006: Changyu Zheng; Corinne M Goldsmith; Fumi Mineshiba; John A Chiorini; Andrew Kerr; Martin L Wenk; Molly K Vallant; Richard D Irwin; Bruce J Baum
Toxicity and biodistribution of a first-generation recombinant adenoviral vector, encoding aquaporin-1, after retroductal delivery to a single rat submandibular gland.
Human gene therapy 2006;17(11):1122-33.
2006: Beatrijs M Lodde; Fumi Mineshiba; Marc R Kok; Jianghua Wang; Changyu Zheng; Michael Schmidt; Ana P Cotrim; MF Kriete; Paul P Tak; Bruce J Baum
NOD mouse model for Sjögren's syndrome: lack of longitudinal stability.
Oral diseases 2006;12(6):566-72.
2006: Beatrijs M Lodde; Bruce J Baum; Paul P Tak; Gabor G Illei
Experience with experimental biological treatment and local gene therapy in Sjogren's syndrome: implications for exocrine pathogenesis and treatment.
Annals of the rheumatic diseases 2006;65(11):1406-13.
2006: Simon D Tran; Takayuki Sugito; Giovanni Dipasquale; Ana P Cotrim; Bidhan Bandyopadhyay; Kathryn Riddle; David Mooney; Marc R Kok; John A Chiorini; Bruce J Baum
Re-engineering primary epithelial cells from rhesus monkey parotid glands for use in developing an artificial salivary gland.
Tissue engineering 2006;12(10):2939-48.
2006: Bruce J Baum; Changyu Zheng; Ana P Cotrim; Corinne M Goldsmith; Jane C Atkinson; Jaime Brahim; John A Chiorini; Antonis Voutetakis; Rose Anne Leakan; Carter Van Waes; James B Mitchell; Christine Delporte; Songlin Wang; Stephen M Kaminsky; Gabor G Illei
Transfer of the AQP1 cDNA for the correction of radiation-induced salivary hypofunction.
Biochimica et biophysica acta 2006;1758(8):1071-7.
2006: Jianghua Wang; Antonis Voutetakis; Fumi Mineshiba; Gabor G Illei; Howard Dang; Chih-Ko Yeh; Bruce J Baum
Effect of serotype 5 adenoviral and serotype 2 adeno- associated viral vector-mediated gene transfer to salivary glands on the composition of saliva.
Human gene therapy 2006;17(4):455-63.
2006: Ana P Cotrim; Fumi Mineshiba; Takayuki Sugito; Yuval Samuni; Bruce J Baum
Salivary gland gene therapy.
Dental clinics of North America 2006;50(2):157-73, vii.
2006: Hisako Katano; Marc R Kok; Ana P Cotrim; Seiichi Yamano; Michael Schmidt; Sandra Afione; Bruce J Baum; John A Chiorini
Enhanced transduction of mouse salivary glands with AAV5-based vectors.
Gene therapy 2006;13(7):594-601.
2006: Changyu Zheng; Antonis Voutetakis; Marc R Kok; Corinne M Goldsmith; G B J Smith; S Elmore; A Nyska; Molly K Vallant; Richard D Irwin; Bruce J Baum
Toxicity and biodistribution of a first-generation recombinant adenoviral vector, in the presence of hydroxychloroquine, following retroductal delivery to a single rat submandibular gland.
Oral diseases 2006;12(2):137-44.
2006: Robert B Wellner; Robert S Redman; William D Swaim; Bruce J Baum
Further evidence for AQP8 expression in the myoepithelium of rat submandibular and parotid glands.
Pflügers Archiv : European journal of physiology 2006;451(5):642-5.
2006: Beatrijs M Lodde; Fumi Mineshiba; Jianghua Wang; Ana P Cotrim; Sandra Afione; Paul P Tak; Bruce J Baum
Effect of human vasoactive intestinal peptide gene transfer in a murine model of Sjogren's syndrome.
Annals of the rheumatic diseases 2006;65(2):195-200.
2006: Bruce J Baum; Simon D Tran
Synergy between genetic and tissue engineering: creating an artificial salivary gland.
Periodontology 2000 2006;41():218-23.
2006: Jianghua Wang; Antonis Voutetakis; M Papa; V M Rivera; Tim Clackson; Beatrijs M Lodde; Fumi Mineshiba; Bruce J Baum
Rapamycin control of transgene expression from a single AAV vector in mouse salivary glands.
Gene therapy 2006;13(2):187-90.
2005: Ana P Cotrim; Anastasia L Sowers; Beatrijs M Lodde; Joseph M Vitolo; Albert Kingman; Angelo Russo; James B Mitchell; Bruce J Baum
Kinetics of tempol for prevention of xerostomia following head and neck irradiation in a mouse model.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(20):7564-8.
2005: Robert B Wellner; Sohee Hong; Ana P Cotrim; William D Swaim; Bruce J Baum
Modifying the NH2 and COOH termini of aquaporin-5: effects on localization in polarized epithelial cells.
Tissue engineering 2005;11(9-10):1449-58.
2005: Changyu Zheng; Bruce J Baum
Evaluation of viral and mammalian promoters for use in gene delivery to salivary glands.
Molecular therapy : the journal of the American Society of Gene Therapy 2005;12(3):528-36.
2005: Jun Li; Zhaochen Shan; Guang-fei Ou; Xiaoyong Liu; Chunmei Zhang; Bruce J Baum; Songlin Wang
Structural and functional characteristics of irradiation damage to parotid glands in the miniature pig.
International journal of radiation oncology, biology, physics 2005;62(5):1510-6.
2005: Thierry Muanza; Ana P Cotrim; Mathew McAuliffe; Anastasia L Sowers; Bruce J Baum; John A Cook; Felix Feldchtein; Paul Amazeen; C Norman Coleman; James B Mitchell
Evaluation of radiation-induced oral mucositis by optical coherence tomography.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(14):5121-7.
2005: Antonis Voutetakis; Ioannis Bossis; Marc R Kok; Weitian Zhang; Jianghua Wang; Ana P Cotrim; Changyu Zheng; John A Chiorini; Lynnette K Nieman; Bruce J Baum
Salivary glands as a potential gene transfer target for gene therapeutics of some monogenetic endocrine disorders.
The Journal of endocrinology 2005;185(3):363-72.
2005: Jianghua Wang; Niamh X Cawley; Antonis Voutetakis; Yazmin M Rodriguez; Corinne M Goldsmith; Lynnette K Nieman; A T M Shamsul Hoque; Stuart J Frank; Chris R Snell; Y Peng Loh; Bruce J Baum
Partial redirection of transgenic human growth hormone secretion from rat salivary glands.
Human gene therapy 2005;16(5):571-83.
2005: Robert B Wellner; Ana P Cotrim; Sohee Hong; William D Swaim; Bruce J Baum
Localization of AQP5/AQP8 chimeras in MDCK-II cells: exchange of the N- and C-termini.
Biochemical and biophysical research communications 2005;330(1):172-7.
2005: Marc R Kok; Antonis Voutetakis; Seiichi Yamano; Jianghua Wang; Ana P Cotrim; Hisako Katano; Ioannis Bossis; John A Chiorini; Simon D Tran; Paul P Tak; Bruce J Baum
Immune responses following salivary gland administration of recombinant adeno-associated virus serotype 2 vectors.
The journal of gene medicine 2005;7(4):432-41.
2005: Z Shan; Jun Li; C Zheng; Xiaoyong Liu; Z Fan; C Zhang; Corinne M Goldsmith; Robert B Wellner; Bruce J Baum; Songlin Wang
Increased fluid secretion after adenoviral-mediated transfer of the human aquaporin-1 cDNA to irradiated miniature pig parotid glands.
Molecular therapy : the journal of the American Society of Gene Therapy 2005;11(3):444-51.
2005: Simon D Tran; Jianghua Wang; Bidhan Bandyopadhyay; Robert S Redman; Amalia Dutra; Evgenia Pak; William D Swaim; J A Gerstenhaber; J M Bryant; Changyu Zheng; Corinne M Goldsmith; Marc R Kok; Robert B Wellner; Bruce J Baum
Primary culture of polarized human salivary epithelial cells for use in developing an artificial salivary gland.
Tissue engineering 2005;11(1-2):172-81.
2004: Bruce J Baum; Antonis Voutetakis; Jianghua Wang
Salivary glands: novel target sites for gene therapeutics.
Trends in molecular medicine 2004;10(12):585-90.
2004: Vidya Sankar; Michael T Brennan; Marc R Kok; Rose Anne Leakan; Janine A Smith; Joan Manny; Bruce J Baum; Stanley R Pillemer
Etanercept in Sjögren's syndrome: a twelve-week randomized, double-blind, placebo-controlled pilot clinical trial.
Arthritis and rheumatism 2004;50(7):2240-5.
2004: Beatrijs M Lodde; Christine Delporte; Corinne M Goldsmith; Paul P Tak; Bruce J Baum
A recombinant adenoviral vector encoding functional vasoactive intestinal peptide.
Biochemical and biophysical research communications 2004;319(1):189-92.
2004: Stanley R Pillemer; Rose Anne Leakan; Vidya Sankar; Joan Manny; Bruce J Baum; Janine Smith; Usha Chaudhry; Philip C Fox; Lida Radfar; Sophie Ligier; Michael T Brennan
Prominent adverse effects of thalidomide in primary Sjögren's syndrome.
Arthritis and rheumatism 2004;51(3):505-6.
2004: Doron J Aframian; R David; Hannah Ben-Bassat; Ela Shai; Dan Deutsch; Bruce J Baum; Aaron Palmon
Characterization of murine autologous salivary gland graft cells: a model for use with an artificial salivary gland.
Tissue engineering 2004;10(5-6):914-20.
2004: Antonis Voutetakis; Jianghua Wang; Bruce J Baum
Utilizing endocrine secretory pathways in salivary glands for systemic gene therapeutics.
Journal of cellular physiology 2004;199(1):1-7.
2004: Jianghua Wang; Antonis Voutetakis; C Zheng; Bruce J Baum
Rapamycin control of exocrine protein levels in saliva after adenoviral vector-mediated gene transfer.
Gene therapy 2004;11(8):729-33.
2004: Antonis Voutetakis; Marc R Kok; Changyu Zheng; Ioannis Bossis; Jianghua Wang; Ana P Cotrim; Natanya Marracino; Corinne M Goldsmith; John A Chiorini; Y Peng Loh; Lynnette K Nieman; Bruce J Baum
Reengineered salivary glands are stable endogenous bioreactors for systemic gene therapeutics.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(9):3053-8.
2004: Joseph M Vitolo; Ana P Cotrim; Anastasia L Sowers; Angelo Russo; Robert B Wellner; Stanley R Pillemer; James B Mitchell; Bruce J Baum
The stable nitroxide tempol facilitates salivary gland protection during head and neck irradiation in a mouse model.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(5):1807-12.
2004: Bruce J Baum
Will dentistry be left behind at the healthcare station?
The Journal of the American College of Dentists 2004;71(2):27-30.
2004: Bruce J Baum
Expanding horizons: modern science enters the mouth.
Refuʾat ha-peh ṿeha-shinayim (1993) 2004;21(1):7-13, 99.
2004: Jun Li; Chanyu Zheng; Xin Zhang; Xiaoyong Liu; Chengmei Zhang; Corinne M Goldsmith; Bruce J Baum; Songlin Wang
Developing a convenient large animal model for gene transfer to salivary glands in vivo.
The journal of gene medicine 2004;6(1):55-63.
2003: Bruce J Baum; Corinne M Goldsmith; Marc R Kok; Beatrijs M Lodde; Norah M van Mello; Antonis Voutetakis; Jianghua Wang; Seiichi Yamano; Changyu Zheng
Advances in vector-mediated gene transfer.
Immunology letters 2003;90(2-3):145-9.
2003: Marc R Kok; Seiichi Yamano; Beatrijs M Lodde; Jianghua Wang; Ross I Couwenhoven; Shoshana Yakar; Antonis Voutetakis; Derek LeRoith; Michael Schmidt; Sandra Afione; Stanley R Pillemer; Marjorie T Tsutsui; Paul P Tak; John A Chiorini; Bruce J Baum
Local adeno-associated virus-mediated interleukin 10 gene transfer has disease-modifying effects in a murine model of Sjögren's syndrome.
Human gene therapy 2003;14(17):1605-18.
2003: Marc R Kok; Bruce J Baum; Paul P Tak; Stanley R Pillemer
Use of localised gene transfer to develop new treatment strategies for the salivary component of Sjögren's syndrome.
Annals of the rheumatic diseases 2003;62(11):1038-46.
2003: Lida Radfar; Yvonne Shea; Steven H Fischer; Vidya Sankar; Rose Anne Leakan; Bruce J Baum; Stanley R Pillemer
Fungal load and candidiasis in Sjögren's syndrome.
Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 2003;96(3):283-7.
2003: Changyu Zheng; Brian C O'Connell; Bruce J Baum
Inclusion of Moloney murine leukemia virus elements upstream of the transgene cassette in an E1-deleted adenovirus leads to an unusual genomic integration in epithelial cells.
Virology 2003;313(2):460-72.
2003: Brian C O'Connell; Changyu Zheng; David Jacobson-Kram; Bruce J Baum
Distribution and toxicity resulting from adenoviral vector administration to a single salivary gland in adult rats.
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2003;32(7):414-21.
2003: Michael T Brennan; Vidya Sankar; Rose Anne Leakan; Margaret Grisius; Michael T Collins; Philip C Fox; Bruce J Baum; Stanley R Pillemer
Sex steroid hormones in primary Sjögren's syndrome.
The Journal of rheumatology 2003;30(6):1267-71.
2003: Bruce J Baum
Can biomedical science be made relevant in dental education? A North American perspective.
European journal of dental education : official journal of the Association for Dental Education in Europe 2003;7(2):49-55; discussion 56-9.
2003: Simon D Tran; Stanley R Pillemer; Amalia Dutra; A John Barrett; Michael J Brownstein; Sharon Key; Evgenia Pak; Rose Anne Leakan; Albert Kingman; Kenneth M Yamada; Bruce J Baum; Eva Mezey
Differentiation of human bone marrow-derived cells into buccal epithelial cells in vivo: a molecular analytical study.
Lancet 2003;361(9363):1084-8.
2003: Changyu Zheng; Jianghua Wang; Bruce J Baum
Integration efficiency of a hybrid adenoretroviral vector.
Biochemical and biophysical research communications 2003;300(1):115-20.
2002: Vidya Sankar; Lorena Baccaglini; M Sawdey; Carl J Wheeler; Stanley R Pillemer; Bruce J Baum; Jane C Atkinson
Salivary gland delivery of pDNA-cationic lipoplexes elicits systemic immune responses.
Oral diseases 2002;8(6):275-81.
2002: DJ Aframian; Simon D Tran; Edna Cukierman; Kenneth M Yamada; Bruce J Baum
Absence of tight junction formation in an allogeneic graft cell line used for developing an engineered artificial salivary gland.
Tissue engineering 2002;8(5):871-8.
2002: DJ Aframian; Robert S Redman; Seiichi Yamano; J Nikolovski; Edna Cukierman; Kenneth M Yamada; MF Kriete; William D Swaim; DJ Mooney; Bruce J Baum
Tissue compatibility of two biodegradable tubular scaffolds implanted adjacent to skin or buccal mucosa in mice.
Tissue engineering 2002;8(4):649-59.
2002: Joseph M Vitolo; Bruce J Baum
The use of gene transfer for the protection and repair of salivary glands.
Oral diseases 2002;8(4):183-91.
2002: A T M Shamsul Hoque; Seiichi Yamano; Xibao Liu; William D Swaim; Corinne M Goldsmith; Christine Delporte; Bruce J Baum
Expression of the aquaporin 8 water channel in a rat salivary epithelial cell.
Journal of cellular physiology 2002;191(3):336-41.
2002: Michael T Brennan; Vidya Sankar; Rose Anne Leakan; David Kleiner; Jane C Atkinson; William E Wilkinson; Bruce J Baum; Stanley R Pillemer
Risk factors for positive minor salivary gland biopsy findings in Sjögren's syndrome and dry mouth patients.
Arthritis and rheumatism 2002;47(2):189-95.
2002: Changyu Zheng; Bruce J Baum
Long-term expression after infection by the hybrid vector AdLTR-luc is from integrated transgene.
Biochemical and biophysical research communications 2002;291(1):34-40.
2002: Seiichi Yamano; Li-Yun Huang; Chuantian Ding; John A Chiorini; Corinne M Goldsmith; Robert B Wellner; Basil Golding; robert kotin; Dorothy E Scott; Bruce J Baum
Recombinant adeno-associated virus serotype 2 vectors mediate stable interleukin 10 secretion from salivary glands into the bloodstream.
Human gene therapy 2002;13(2):287-98.
2002: Bruce J Baum; John Scott; Matthias Bickel; Giorgio Gombos; John Greenspan; Wei Guo; No-Hee Park; David Purdell-Lewis; Richard R Ranney; Eli Schwarz; Greg Seymour; Katsumi Uoshima
5.3 Global challenges in research and strategic planning.
European journal of dental education : official journal of the Association for Dental Education in Europe 2002;6 Suppl 3():179-84.
2002: Bruce J Baum; John Scott
5.0 Introduction to Theme 5: New challenges and strategic planning in research.
European journal of dental education : official journal of the Association for Dental Education in Europe 2002;6 Suppl 3():161.
2002: Bruce J Baum; Robert B Wellner; Changyu Zheng
Gene transfer to salivary glands.
International review of cytology 2002;213():93-146.
2002: Bruce J Baum; Marc R Kok; Simon D Tran; Seiichi Yamano
The impact of gene therapy on dentistry: a revisiting after six years.
Journal of the American Dental Association (1939) 2002;133(1):35-44.
2001: Changyu Zheng; A T M Shamsul Hoque; VR Braddon; Bruce J Baum; Brian C O'Connell
Evaluation of salivary gland acinar and ductal cell-specific promoters in vivo with recombinant adenoviral vectors.
Human gene therapy 2001;12(18):2215-23.
2001: Seiichi Yamano; Dorothy E Scott; Li-Yun Huang; Malgorzata G Mikolajczyk; Stanley R Pillemer; John A Chiorini; Basil Golding; Bruce J Baum
Protection from experimental endotoxemia by a recombinant adeno-associated virus encoding interleukin 10.
The journal of gene medicine 2001;3(5):450-7.
2001: R K Simmons; Bruce J Baum
Transferring genes to salivary glands.
Journal of dental education 2001;65(9):907-10.
2001: Robert B Wellner; Bruce J Baum
Polarized sorting of aquaporins 5 and 8 in stable MDCK-II transfectants.
Biochemical and biophysical research communications 2001;285(5):1253-8.
2001: DJ Aframian; Changyu Zheng; Corinne M Goldsmith; J Nikolovski; Edna Cukierman; Kenneth M Yamada; DJ Mooney; Henning Birkedal-Hansen; Bruce J Baum
Using HSV-thymidine kinase for safety in an allogeneic salivary graft cell line.
Tissue engineering 2001;7(4):405-13.
2001: A T M Shamsul Hoque; Lorena Baccaglini; Bruce J Baum
Hydroxychloroquine enhances the endocrine secretion of adenovirus-directed growth hormone from rat submandibular glands in vivo.
Human gene therapy 2001;12(10):1333-41.
2001: A T M Shamsul Hoque; Seiichi Yamano; Lorena Baccaglini; Bruce J Baum
Using salivary glands as a tissue target for gene therapeutics.
Journal of drug targeting 2001;9(6):485-94.
2001: Lorena Baccaglini; A T Shamsul Hoque; Robert B Wellner; Corinne M Goldsmith; Robert S Redman; Vidya Sankar; Albert Kingman; K M Barnhart; Carl J Wheeler; Bruce J Baum
Cationic liposome-mediated gene transfer to rat salivary epithelial cells in vitro and in vivo.
The journal of gene medicine 2001;3(1):82-90.
2000: Bruce J Baum
Prospects for re-engineering salivary glands.
Advances in dental research 2000;14():84-8.
2000: Robert B Wellner; A T M Shamsul Hoque; Corinne M Goldsmith; Bruce J Baum
Evidence that aquaporin-8 is located in the basolateral membrane of rat submandibular gland acinar cells.
Pflügers Archiv : European journal of physiology 2000;441(1):49-56.
2000: Harold Charles Slavkin; Bruce J Baum
Relationship of dental and oral pathology to systemic illness.
JAMA : the journal of the American Medical Association 2000;284(10):1215-7.
2000: Lorena Baccaglini; Stanley R Pillemer; Bruce J Baum
Sjögren's syndrome: a possible pathogenetic mechanism involving somatostatin.
Oral diseases 2000;6(5):264-6.
2000: Changyu Zheng; Corinne M Goldsmith; Brian C O'Connell; Bruce J Baum
Adenoviral vector cytotoxicity depends in part on the transgene encoded.
Biochemical and biophysical research communications 2000;274(3):767-71.
2000: A T M Shamsul Hoque; Olga A Sedelnikova; AN Luu; William D Swaim; Igor G Panyutin; Bruce J Baum
Use of polyethylenimine-adenovirus complexes to examine triplex formation in intact cells.
Antisense & nucleic acid drug development 2000;10(4):229-41.
2000: Bruce J Baum; Corinne M Goldsmith; A T M Shamsul Hoque; Robert B Wellner; Lorena Baccaglini; Chuantian Ding; Seiichi Yamano; C Zheng; DJ Aframian; Changyu Zheng; D J Aframian; Brian C O'Connell
Salivary glands as a model for craniofacial applications of gene transfer.
International journal of oral and maxillofacial surgery 2000;29(3):163-6.
2000: DJ Aframian; Edna Cukierman; J Nikolovski; DJ Mooney; Kenneth M Yamada; Bruce J Baum
The growth and morphological behavior of salivary epithelial cells on matrix protein-coated biodegradable substrata.
Tissue engineering 2000;6(3):209-16.
2000: Seiichi Yamano; Bruce J Baum
Prospects for gene-based immunopharmacology in salivary glands.
Japanese journal of pharmacology 2000;82(4):281-6.
2000: A T M Shamsul Hoque; Xibao Liu; H Kagami; William D Swaim; Robert B Wellner; Brian C O'Connell; Indu S Ambudkar; Bruce J Baum
Construction and function of a recombinant adenovirus encoding a human aquaporin 1-green fluorescent protein fusion product.
Cancer gene therapy 2000;7(3):476-85.
2000: Bruce J Baum; D J Mooney
The impact of tissue engineering on dentistry.
Journal of the American Dental Association (1939) 2000;131(3):309-18.
2000: S Wang; Bruce J Baum; Seiichi Yamano; Mahesh H Mankani; D Sun; M Jonsson; C Davis; F L Graham; J Gauldie; Jane C Atkinson
Adenoviral-mediated gene transfer to mouse salivary glands.
Journal of dental research 2000;79(2):701-8.
2000: Changyu Zheng; Bruce J Baum; Michael Iadarola; Brian C O'Connell
Genomic integration and gene expression by a modified adenoviral vector.
Nature biotechnology 2000;18(2):176-80.
1999: Bruce J Baum
Crowning achievements in dentistry.
Lancet 1999;354 Suppl():SIV12.
1999: Bruce J Baum; M E Berkman; Yitzhak Marmary; Corinne M Goldsmith; Lorena Baccaglini; S Wang; Robert B Wellner; A T M Shamsul Hoque; Jane C Atkinson; H Yamagishi; H Kagami; AF Parlow; Julie Chao
Polarized secretion of transgene products from salivary glands in vivo.
Human gene therapy 1999;10(17):2789-97.
1999: AC O'Connell; Lorena Baccaglini; Philip C Fox; Brian C O'Connell; Daniel R Kenshalo; H Oweisy; A T M Shamsul Hoque; D Sun; L L Herscher; VR Braddon; Christine Delporte; Bruce J Baum
Safety and efficacy of adenovirus-mediated transfer of the human aquaporin-1 cDNA to irradiated parotid glands of non-human primates.
Cancer gene therapy 1999;6(6):505-13.
1999: Seiichi Yamano; Jane C Atkinson; Bruce J Baum; Philip C Fox
Salivary gland cytokine expression in NOD and normal BALB/c mice.
Clinical immunology (Orlando, Fla.) 1999;92(3):265-75.
1999: A T Shamsul Hoque; Igor G Panyutin; Bruce J Baum
Use of triplex-forming oligonucleotides and adenoviral constructs for studying the regulation of gene expression.
Methods (San Diego, Calif.) 1999;18(3):266-72.
1999: Bruce J Baum; S Wang; Edna Cukierman; Christine Delporte; H Kagami; Yitzhak Marmary; Philip C Fox; DJ Mooney; Kenneth M Yamada
Re-engineering the functions of a terminally differentiated epithelial cell in vivo.
Annals of the New York Academy of Sciences 1999;875():294-300.
1999: S Wang; Edna Cukierman; William D Swaim; K M Yamada; Bruce J Baum
Extracellular matrix protein-induced changes in human salivary epithelial cell organization and proliferation on a model biological substratum.
Biomaterials 1999;20(11):1043-9.
1999: Bruce J Baum; Brian C O'Connell
The need to introduce gene therapy to the dental curriculum.
European journal of dental education : official journal of the Association for Dental Education in Europe 1999;3(2):49-51.
1999: S Wang; Bruce J Baum; H Kagami; Changyu Zheng; Brian C O'Connell; Jane C Atkinson
Effect of clodronate on macrophage depletion and adenoviral-mediated transgene expression in salivary glands.
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 1999;28(4):145-51.
1999: Bruce J Baum; Brian C O'Connell
In vivo gene transfer to salivary glands.
Critical reviews in oral biology and medicine : an official publication of the American Association of Oral Biologists 1999;10(3):276-83.
1999: Yitzhak Marmary; AF Parlow; Corinne M Goldsmith; X He; Robert B Wellner; K Satomura; MF Kriete; Pamela Robey; Lynnette K Nieman; Bruce J Baum
Construction and in vivo efficacy of a replication-deficient recombinant adenovirus encoding murine growth hormone.
Endocrinology 1999;140(1):260-5.
1998: VR Braddon; John A Chiorini; S Wang; robert kotin; Bruce J Baum
Adenoassociated virus-mediated transfer of a functional water channel into salivary epithelial cells in vitro and in vivo.
Human gene therapy 1998;9(18):2777-85.
1998: AC O'Connell; CD Lillibridge; Changyu Zheng; Bruce J Baum; Brian C O'Connell; Indu S Ambudkar
Gamma-irradiation-induced cell cycle arrest and cell death in a human submandibular gland cell line: effect of E2F1 expression.
Journal of cellular physiology 1998;177(2):264-73.
1998: Christine Delporte; Bruce J Baum
Preclinical and biological studies using recombinant adenoviruses encoding aquaporins 1 and 5.
European journal of morphology 1998;36 Suppl():118-22.
1998: Bruce J Baum; C Davis
Clinical research, dental education, and the NIH Clinical Research Training Program.
Journal of dental education 1998;62(8):592-6; discussion 597-8.
1998: Bruce J Baum; Jane C Atkinson; Lorena Baccaglini; M E Berkman; Jaime Brahim; C Davis; HE Lancaster; Yitzhak Marmary; AC O'Connell; Brian C O'Connell; S Wang; Y Xu; H Yamagishi; Philip C Fox
The mouth is a gateway to the body: gene therapy in 21st-century dental practice.
Journal of the California Dental Association 1998;26(6):455-60.
1998: Philip C Fox; M Brennan; Stanley R Pillemer; Lida Radfar; S Yamano; Bruce J Baum
Sjögren's syndrome: a model for dental care in the 21st century.
Journal of the American Dental Association (1939) 1998;129(6):719-28.
1998: Christine Delporte; A T M Shamsul Hoque; J A Kulakusky; VR Braddon; Corinne M Goldsmith; Robert B Wellner; Bruce J Baum
Relationship between adenovirus-mediated aquaporin 1 expression and fluid movement across epithelial cells.
Biochemical and biophysical research communications 1998;246(3):584-8.
1998: R M Nagler; Bruce J Baum; G Miller; Philip C Fox
Long-term salivary effects of single-dose head and neck irradiation in the rat.
Archives of oral biology 1998;43(4):297-303.
1998: X He; Corinne M Goldsmith; Yitzhak Marmary; Robert B Wellner; AF Parlow; Lynnette K Nieman; Bruce J Baum
Systemic action of human growth hormone following adenovirus-mediated gene transfer to rat submandibular glands.
Gene therapy 1998;5(4):537-41.
1998: H Kagami; Jane C Atkinson; S M Michalek; B Handelman; S Yu; Bruce J Baum; B O'Connell
Repetitive adenovirus administration to the parotid gland: role of immunological barriers and induction of oral tolerance.
Human gene therapy 1998;9(3):305-13.
1998: X He; G A Kuijpers; Gertrud Goping; J A Kulakusky; Changyu Zheng; Christine Delporte; Chung-Ming Tse; Robert S Redman; Mark Donowitz; Harvey B Pollard; Bruce J Baum
A polarized salivary cell monolayer useful for studying transepithelial fluid movement in vitro.
Pflügers Archiv : European journal of physiology 1998;435(3):375-81.
1998: Christine Delporte; G Miller; H Kagami; CD Lillibridge; Brian C O'Connell; Jane C Atkinson; Bruce J Baum
Safety of salivary gland-administered replication-deficient recombinant adenovirus in rats.
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 1998;27(1):34-8.
1997: Christine Delporte; Igor G Panyutin; Olga A Sedelnikova; CD Lillibridge; Brian C O'Connell; Bruce J Baum
Triplex-forming oligonucleotides can modulate aquaporin-5 gene expression in epithelial cells.
Antisense & nucleic acid drug development 1997;7(5):523-9.
1997: Angela Janet Wu; ZJ Chen; Elaine Kan; Bruce J Baum
Interferon-gamma-induced JAK2 and STAT1 signalling in a human salivary gland cell line.
Journal of cellular physiology 1997;173(1):110-4.
1997: Christine Delporte; Robert S Redman; Bruce J Baum
Relationship between the cellular distribution of the alpha(v)beta3/5 integrins and adenoviral infection in salivary glands.
Laboratory investigation; a journal of technical methods and pathology 1997;77(2):167-73.
1997: Bruce J Baum
Introduction to the symposium Science Education and Dentistry: Improving the Connection.
Journal of dental education 1997;61(5):405-6.
1997: Angela Janet Wu; Robert M Lafrenie; C Park; W Apinhasmit; ZJ Chen; Henning Birkedal-Hansen; Kenneth M Yamada; William Stetler-Stevenson; Bruce J Baum
Modulation of MMP-2 (gelatinase A) and MMP-9 (gelatinase B) by interferon-gamma in a human salivary gland cell line.
Journal of cellular physiology 1997;171(2):117-24.
1997: Christine Delporte; Brian C O'Connell; X He; HE Lancaster; AC O'Connell; Peter Agre; Bruce J Baum
Increased fluid secretion after adenoviral-mediated transfer of the aquaporin-1 cDNA to irradiated rat salivary glands.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(7):3268-73.
1997: Rafael M Nagler; Yitzhak Marmary; Philip C Fox; Bruce J Baum; R Har-El; Mordechai Chevion
Irradiation-induced damage to the salivary glands: the role of redox-active iron and copper.
Radiation research 1997;147(4):468-76.
1997: Bruce J Baum
The absence of a culture of science in dental education.
European journal of dental education : official journal of the Association for Dental Education in Europe 1997;1(1):2-5.
1997: Bruce J Baum; P C Fox; Lawrence Tabak
Columbia, salivary research, plus Irwin Mandel equal a special combination for dentistry.
Journal of dental research 1997;76(2):631-3.
1997: X He; Chung-Ming Tse; Mark Donowitz; S L Alper; Sherif E Gabriel; Bruce J Baum
Polarized distribution of key membrane transport proteins in the rat submandibular gland.
Pflügers Archiv : European journal of physiology 1997;433(3):260-8.
1996: Brian C O'Connell; T Xu; THOMAS WALSH; T Sein; A Mastrangeli; Helen-Ann Brown Epstein; F G Oppenheim; Bruce J Baum
Transfer of a gene encoding the anticandidal protein histatin 3 to salivary glands.
Human gene therapy 1996;7(18):2255-61.
1996: Christine Delporte; Z J Chen; Bruce J Baum
Aquaporin 1 expression during the cell cycle in A5 cells.
Biochemical and biophysical research communications 1996;228(2):223-8.
1996: H Kagami; Brian C O'Connell; Bruce J Baum
Evidence for the systemic delivery of a transgene product from salivary glands.
Human gene therapy 1996;7(17):2177-84.
1996: Bruce J Baum
Perspectives from dental research.
Journal of dental education 1996;60(11):889-90.
1996: Christine Delporte; Brian C O'Connell; X He; Indu S Ambudkar; Peter Agre; Bruce J Baum
Adenovirus-mediated expression of aquaporin-5 in epithelial cells.
The Journal of biological chemistry 1996;271(36):22070-5.
1996: R M Nagler; Bruce J Baum; Philip C Fox
A 2 week pair-fed study of early X-irradiation effects on rat major salivary gland function.
Archives of oral biology 1996;41(7):713-7.
1996: M R Adesanya; Robert S Redman; Bruce J Baum; Brian C O'Connell
Immediate inflammatory responses to adenovirus-mediated gene transfer in rat salivary glands.
Human gene therapy 1996;7(9):1085-93.
1996: Angela Janet Wu; Z J Chen; M Tsokos; Brian C O'Connell; Indu S Ambudkar; Bruce J Baum
Interferon-gamma induced cell death in a cultured human salivary gland cell line.
Journal of cellular physiology 1996;167(2):297-304.
1996: Angela Janet Wu; Z J Chen; Bruce J Baum; Indu S Ambudkar
Interferon-gamma induces persistent depletion of internal Ca2+ stores in a human salivary gland cell line.
The American journal of physiology 1996;270(2 Pt 1):C514-21.
1996: Bruce J Baum
The dental curriculum: what should be new in the 21st century?
Journal of public health dentistry 1996;56(5 Spec No):286-90.
1995: K Sawaki; Bruce J Baum; G S Roth; Indu S Ambudkar
Decreased m3-muscarinic and alpha 1-adrenergic receptor stimulation of PIP2 hydrolysis in parotid gland membranes from aged rats: defect in activation of G alpha q/11.
Archives of biochemistry and biophysics 1995;322(2):319-26.
1995: K W Lazowski; J Li; Christine Delporte; Bruce J Baum
Evidence for the presence of a Hg-inhibitable water-permeability pathway and aquaporin 1 in A5 salivary epithelial cells.
Journal of cellular physiology 1995;164(3):613-9.
1995: Y Hiramatsu; William Eckelman; Jorge Carrasquillo; R S Miletich; I H Valdez; R H Kurrasch; A A Macynski; Chang H Paik; R D Neumann; Bruce J Baum
Kinetic analysis of muscarinic receptors in human brain and salivary gland in vivo.
The American journal of physiology 1995;268(6 Pt 2):R1491-9.
1995: Brian C O'Connell; Kelly G Ten Hagen; K W Lazowski; Lawrence Tabak; Bruce J Baum
Facilitated DNA transfer to rat submandibular gland in vivo and GRP-Ca gene regulation.
The American journal of physiology 1995;268(6 Pt 1):G1074-8.
1995: Bruce J Baum; Brian C O'Connell
The impact of gene therapy on dentistry.
Journal of the American Dental Association (1939) 1995;126(2):179-89.
1995: K Sawaki; Bruce J Baum; Indu S Ambudkar
Alpha 1-adrenergic and m3-muscarinic receptor stimulation of phosphatidylinositol 4,5-bisphosphate-specific phospholipase C are independently mediated by G alpha q/11 in rat parotid gland membranes.
Archives of biochemistry and biophysics 1995;316(1):535-40.
1995: Angela Janet Wu; Bruce J Baum; Jonathan A Ship
Extended stimulated parotid and submandibular secretion in a healthy young and old population.
The journals of gerontology. Series A, Biological sciences and medical sciences 1995;50A(1):M45-8.
1994: Angela Janet Wu; R H Kurrasch; J Katz; Philip C Fox; Bruce J Baum; Jane C Atkinson
Effect of tumor necrosis factor-alpha and interferon-gamma on the growth of a human salivary gland cell line.
Journal of cellular physiology 1994;161(2):217-26.
1994: J Li; Søren Nielsen; Y Dai; K W Lazowski; E I Christensen; Lawrence Tabak; Bruce J Baum
Examination of rat salivary glands for the presence of the aquaporin CHIP.
Pflügers Archiv : European journal of physiology 1994;428(5-6):455-60.
1994: Y Hiramatsu; R Kawai; R C Reba; Ronald Blasberg; Bruce J Baum
Kinetic analysis of rat exocrine gland muscarinic receptors in vivo.
The Journal of pharmacology and experimental therapeutics 1994;269(3):1205-12.
1994: Y Hiramatsu; William Eckelman; Bruce J Baum
Interaction of iodinated quinuclidinyl benzilate enantiomers with M3 muscarinic receptors.
Life sciences 1994;54(23):1777-83.
1994: Y Hiramatsu; R M Nagler; Philip C Fox; Bruce J Baum
Rat salivary gland blood flow and blood-to-tissue partition coefficients following X-irradiation.
Archives of oral biology 1994;39(1):77-80.
1993: Y Dai; Bruce J Baum
Relationship between muscarinic receptor occupancy and response in rat parotid acinar cells.
The American journal of physiology 1993;265(6 Pt 1):G1122-7.
1993: R M Nagler; Bruce J Baum; Philip C Fox
Effects of X irradiation on the function of rat salivary glands at 3 and 40 days.
Radiation research 1993;136(3):392-6.
1993: R M Nagler; Bruce J Baum; Philip C Fox
Acute effects of X irradiation on the function of rat salivary glands.
Radiation research 1993;136(1):42-7.
1993: Bruce J Baum
Principles of saliva secretion.
Annals of the New York Academy of Sciences 1993;694():17-23.
1993: K Sawaki; Y Hiramatsu; Bruce J Baum; Indu S Ambudkar
Involvement of G alpha q/11 in m3-muscarinic receptor stimulation of phosphatidylinositol 4,5 bisphosphate-specific phospholipase C in rat parotid gland membranes.
Archives of biochemistry and biophysics 1993;305(2):546-50.
1993: Angela Janet Wu; Jane C Atkinson; Philip C Fox; Bruce J Baum; Jonathan A Ship
Cross-sectional and longitudinal analyses of stimulated parotid salivary constituents in healthy, different-aged subjects.
Journal of gerontology 1993;48(5):M219-24.
1993: Bruce J Baum; Y Hiramatsu; W G Kohn; I H Valdez
New approaches for determining the site of salivary fluid secretory disorders.
Advances in dental research 1993;7(2):220-4.
1993: Jonathan A Ship; Bruce J Baum
Old age in health and disease. Lessons from the oral cavity.
Oral surgery, oral medicine, and oral pathology 1993;76(1):40-4.
1993: Bruce J Baum
Response to the dental scientist model.
Journal of dental education 1993;57(5):356-8.
1993: Y Hiramatsu; R Kawai; R C Reba; T R Simon; Bruce J Baum; Ronald Blasberg
Kinetic analysis of rat parotid gland muscarinic receptors in vivo: comparison with brain and heart.
The American journal of physiology 1993;264(3 Pt 1):G541-52.
1993: L S Royce; M C Kibbey; P Mertz; Hynda K Kleinman; Bruce J Baum
Human neoplastic submandibular intercalated duct cells express an acinar phenotype when cultured on a basement membrane matrix.
Differentiation; research in biological diversity 1993;52(3):247-55.
1993: Indu S Ambudkar; Y Hiramatsu; T Lockwich; Bruce J Baum
Activation and regulation of calcium entry in rat parotid gland acinar cells.
Critical reviews in oral biology and medicine : an official publication of the American Association of Oral Biologists 1993;4(3-4):421-5.
1993: M D Kaplan; Bruce J Baum
The functions of saliva.
Dysphagia 1993;8(3):225-9.
1993: Bruce J Baum; Y Dai; Y Hiramatsu; V J Horn; Indu S Ambudkar
Signaling mechanisms that regulate saliva formation.
Critical reviews in oral biology and medicine : an official publication of the American Association of Oral Biologists 1993;4(3-4):379-84.
1992: Indu S Ambudkar; T Lockwich; Y Hiramatsu; Bruce J Baum
Calcium entry in rat parotid acinar cells.
Molecular and cellular biochemistry 1992;114(1-2):73-7.
1992: Y Hiramatsu; Bruce J Baum; Indu S Ambudkar
Elevation of cytosolic [Ca2+] due to intracellular Ca2+ release retards carbachol stimulation of divalent cation entry in rat parotid gland acinar cells.
The Journal of membrane biology 1992;129(3):277-86.
1992: Y Hiramatsu; V J Horn; Bruce J Baum; Indu S Ambudkar
Characterization of polyphosphoinositide-specific phospholipase C in rat parotid gland membranes.
Archives of biochemistry and biophysics 1992;297(2):368-76.
1992: G Cherry-Peppers; John D Sorkin; Reubin Andres; Bruce J Baum; Jonathan A Ship
Salivary gland function and glucose metabolic status.
Journal of gerontology 1992;47(4):M130-4.
1992: Bruce J Baum
Age-related vulnerability.
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 1992;106(6):730-2.
1992: Bruce J Baum
Commentary on "Education for dental practice in the year 2005: a beginning dialogue".
Journal of dental education 1992;56(6):377-8.
1992: P M Mertz; Philip C Fox; A Pluta; Bruce J Baum; E E Kousvelari
Effects of ionizing radiation and beta-adrenergic stimulation on the expression of early response genes in rat parotid glands.
Radiation research 1992;130(1):104-12.
1992: L M Mertz; Bruce J Baum; Indu S Ambudkar
Membrane potential modulates divalent cation entry in rat parotid acini.
The Journal of membrane biology 1992;126(2):183-93.
1992: W G Kohn; E Grossman; Philip C Fox; M Ines Armando; David S Goldstein; Bruce J Baum
Effect of ionizing radiation on sympathetic nerve function in rat parotid glands.
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 1992;21(3):134-7.
1992: M C Kibbey; L S Royce; Martin Dym; Bruce J Baum; Hynda K Kleinman
Glandular-like morphogenesis of the human submandibular tumor cell line A253 on basement membrane components.
Experimental cell research 1992;198(2):343-51.
1992: Chih-Ko Yeh; B Handelman; Philip C Fox; Bruce J Baum
Further studies of salivary inhibition of HIV-1 infectivity.
Journal of acquired immune deficiency syndromes 1992;5(9):898-903.
1992: Bruce J Baum; Jonathan A Ship; Angela Janet Wu
Salivary gland function and aging: a model for studying the interaction of aging and systemic disease.
Critical reviews in oral biology and medicine : an official publication of the American Association of Oral Biologists 1992;4(1):53-64.
1991: Y S Dai; Indu S Ambudkar; V J Horn; Chih-Ko Yeh; E E Kousvelari; S J Wall; M Li; Robert P Yasuda; Barry B Wolfe; Bruce J Baum
Evidence that M3 muscarinic receptors in rat parotid gland couple to two second messenger systems.
The American journal of physiology 1991;261(6 Pt 1):C1063-73.
1991: Chih-Ko Yeh; P M Mertz; C Oliver; Bruce J Baum; E E Kousvelari
Cellular characteristics of long-term cultured rat parotid acinar cells.
In vitro cellular & developmental biology : journal of the Tissue Culture Association 1991;27A(9):707-12.
1991: V J Horn; Bruce J Baum; Indu S Ambudkar
Muscarinic receptor antagonist effects in parotid acini and M1-CHO cells: evidence of G protein involvement.
Biochemical and biophysical research communications 1991;177(2):784-9.
1991: Philip C Fox; Jane C Atkinson; A A Macynski; Andy Wolff; D S Kung; I H Valdez; W Jackson; R A Delapenha; J Shiroky; Bruce J Baum
Pilocarpine treatment of salivary gland hypofunction and dry mouth (xerostomia).
Archives of internal medicine 1991;151(6):1149-52.
1991: L S Royce; Bruce J Baum
Physiologic levels of salivary epidermal growth factor stimulate migration of an oral epithelial cell line.
Biochimica et biophysica acta 1991;1092(3):401-3.
1991: Y Hiramatsu; Indu S Ambudkar; Bruce J Baum
Characterization of high affinity GTPase activity correlated to beta-adrenergic receptor stimulation of adenylyl cyclase in rat parotid membranes.
Biochimica et biophysica acta 1991;1092(3):391-6.
1991: V J Horn; Indu S Ambudkar; Bruce J Baum
High affinity quinuclidinyl benzilate binding to rat parotid membranes requires muscarinic receptor. G protein interactions.
FEBS letters 1991;282(2):289-92.
1991: Andy Wolff; Jonathan A Ship; C A Tylenda; Philip C Fox; Bruce J Baum
Oral mucosal appearance is unchanged in healthy, different-aged persons.
Oral surgery, oral medicine, and oral pathology 1991;71(5):569-72.
1991: Bruce J Baum
Has modern biology entered the mouth? The clinical impact of biological research.
Journal of dental education 1991;55(5):299-303.
1991: Jonathan A Ship; Philip C Fox; Bruce J Baum
How much saliva is enough? 'Normal' function defined.
Journal of the American Dental Association (1939) 1991;122(3):63-9.
1990: Indu S Ambudkar; V J Horn; Y S Dai; Bruce J Baum
Evidence against a role for a pertussis toxin-sensitive G protein in Ca2+ mobilization in rat parotid acinar cells.
Biochimica et biophysica acta 1990;1055(3):259-64.
1990: L M Mertz; Bruce J Baum; Indu S Ambudkar
Refill status of the agonist-sensitive Ca2+ pool regulates Mn2+ influx into parotid acini.
The Journal of biological chemistry 1990;265(25):15010-4.
1990: J M Weiffenbach; C A Tylenda; Bruce J Baum
Oral sensory changes in aging.
Journal of gerontology 1990;45(4):M121-5.
1990: Andy Wolff; Philip C Fox; Jonathan A Ship; Jane C Atkinson; A A Macynski; Bruce J Baum
Oral mucosal status and major salivary gland function.
Oral surgery, oral medicine, and oral pathology 1990;70(1):49-54.
1990: X J He; X Z Wu; R James Turner; Bruce J Baum
Evidence for two modes of Ca2+ entry following muscarinic stimulation of a human salivary epithelial cell line.
The Journal of membrane biology 1990;115(2):159-66.
1990: X J He; X Z Wu; Bruce J Baum
The effect of N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide (W-7) on muscarinic receptor-induced Ca2+ mobilization in a human salivary epithelial cell line.
Pflügers Archiv : European journal of physiology 1990;416(1-2):36-42.
1990: L M Mertz; V J Horn; Bruce J Baum; Indu S Ambudkar
Calcium entry in rat parotid acini: activation by carbachol and aluminum fluoride.
The American journal of physiology 1990;258(4 Pt 1):C654-61.
1990: Jonathan A Ship; Charles DeCarli; Robert P Friedland; Bruce J Baum
Diminished submandibular salivary flow in dementia of the Alzheimer type.
Journal of gerontology 1990;45(2):M61-6.
1990: X Z Wu; X J He; Bruce J Baum
Muscarinic regulation of Ca2+ mobilization in a human salivary myoepithelial cell line.
Biochemical pharmacology 1990;39(3):612-5.
1990: V J Horn; Bruce J Baum; Indu S Ambudkar
Attenuation of inositol trisphosphate generation and cytosolic Ca2+ elevation in dispersed rat parotid acini stimulated simultaneously at muscarinic and alpha 1-adrenergic receptors.
Biochemical and biophysical research communications 1990;166(2):967-72.
1990: Bruce J Baum; Chih-Ko Yeh; E E Kousvelari
Influence of beta-adrenergic stimulation on glycosylation of a major, secretory N-linked glycoprotein from rat parotid salivary gland.
Archives of oral biology 1990;35(3):201-7.
1990: Jane C Atkinson; Chih-Ko Yeh; F G Oppenheim; D Bermudez; Bruce J Baum; Philip C Fox
Elevation of salivary antimicrobial proteins following HIV-1 infection.
Journal of acquired immune deficiency syndromes 1990;3(1):41-8.
1990: Bruce J Baum; Indu S Ambudkar; Joseph I Helman; V J Horn; J E Melvin; L M Mertz; R James Turner
Dispersed salivary gland acinar cell preparations for use in studies of neuroreceptor-coupled secretory events.
Methods in enzymology 1990;192():26-37.
1989: V J Horn; Bruce J Baum; Indu S Ambudkar
Evidence for the convergence of beta-adrenergic and muscarinic signalling systems at a post-receptor site.
FEBS letters 1989;258(1):13-6.
1989: Jane C Atkinson; Chih-Ko Yeh; D Bermudez; Philip C Fox; Bruce J Baum
Longitudinal evaluation of major salivary gland function in HIV-1 infected patients.
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 1989;18(8):469-70.
1989: Philip C Fox; Andy Wolff; Chih-Ko Yeh; Jane C Atkinson; Bruce J Baum
Salivary inhibition of HIV-1 infectivity: functional properties and distribution in men, women, and children.
Journal of the American Dental Association (1939) 1989;118(6):709-11.
1989: Chih-Ko Yeh; Philip C Fox; C H Fox; William D Travis; H Clifford Lane; Bruce J Baum
Kaposi's sarcoma of the parotid gland in acquired immunodeficiency syndrome.
Oral surgery, oral medicine, and oral pathology 1989;67(3):308-12.
1989: X J He; X Z Wu; Robert B Wellner; Bruce J Baum
Muscarinic receptor regulation of Ca2+ mobilization in a human salivary cell line.
Pflügers Archiv : European journal of physiology 1989;413(5):505-10.
1989: Indu S Ambudkar; V J Horn; Bruce J Baum
ATP-dependent Ca2+ transport in the rat parotid basolateral plasma membrane is regulated by calmodulin.
Archives of biochemistry and biophysics 1989;268(2):576-84.
1989: X J He; X Z Wu; A M Brown; Robert B Wellner; Bruce J Baum
Characteristics of alpha 1-adrenergic receptors in a rat salivary cell line, RSMT-A5.
General pharmacology 1989;20(2):175-81.
1989: Lily Mirels; Bruce J Baum; E Kousvelari
Dissociation between c-fos gene expression and DNA synthesis in rat parotid glands.
Archives of oral biology 1989;34(7):511-5.
1988: Bruce J Baum; Indu S Ambudkar; V J Horn
Evidence that ATP-dependent Ca2+ transport in rat parotid microsomal membranes requires charge compensation.
The Biochemical journal 1988;254(3):649-54.
1988: V J Horn; Bruce J Baum; Indu S Ambudkar
Beta-adrenergic receptor stimulation induces inositol trisphosphate production and Ca2+ mobilization in rat parotid acinar cells.
The Journal of biological chemistry 1988;263(25):12454-60.
1988: C A Tylenda; Jonathan A Ship; Philip C Fox; Bruce J Baum
Evaluation of submandibular salivary flow rate in different age groups.
Journal of dental research 1988;67(9):1225-8.
1988: Bruce J Baum; Michael W Roberts; Jaime Brahim; Philip C Fox
The National Institute of Dental Research Clinical Dental Staff Fellowship.
Journal of dental education 1988;52(9):535-6.
1988: J E Melvin; X J He; Bruce J Baum
Sympathetic denervation fails to produce beta adrenergic supersensitivity in adult rat parotid gland.
The Journal of pharmacology and experimental therapeutics 1988;246(3):935-40.
1988: Robert B Wellner; X J He; Yitzhak Marmary; Bruce J Baum
Functional beta-adrenergic receptors in a human mammary cell line (HBL-100).
Biochemical pharmacology 1988;37(15):3035-7.
1988: Bruce J Baum; Indu S Ambudkar
Regulation of calcium handling by rat parotid acinar cells.
Molecular and cellular biochemistry 1988;82(1-2):67-73.
1988: Indu S Ambudkar; J E Melvin; Bruce J Baum
Alpha 1-adrenergic regulation of Cl- and Ca2+ movements in rat parotid acinar cells.
Pflügers Archiv : European journal of physiology 1988;412(1-2):75-9.
1988: Indu S Ambudkar; Bruce J Baum
Modulation of ATP-dependent Ca2+ transport in rat parotid basolateral membrane vesicles by K+ + Cl- flux.
Biochimica et biophysica acta 1988;941(2):198-208.
1988: X J He; X Z Wu; Bruce J Baum
Protein kinase C differentially inhibits muscarinic receptor operated Ca2+ release and entry in human salivary cells.
Biochemical and biophysical research communications 1988;152(3):1062-9.
1988: Philip C Fox; Andy Wolff; Chih-Ko Yeh; Jane C Atkinson; Bruce J Baum
Saliva inhibits HIV-1 infectivity.
Journal of the American Dental Association (1939) 1988;116(6):635-7.
1988: Indu S Ambudkar; Bruce J Baum
ATP-dependent calcium transport in rat parotid basolateral membrane vesicles is modulated by membrane potential.
The Journal of membrane biology 1988;102(1):59-69.
1988: Indu S Ambudkar; B L Kuyatt; G S Roth; Bruce J Baum
Modification of ATP-dependent Ca2+ transport in rat parotid basolateral membranes during aging.
Mechanisms of ageing and development 1988;43(1):45-60.
1988: E E Kousvelari; D K Banerjee; L Murty; Bruce J Baum
N-linked protein glycosylation in the rat parotid gland during aging.
Mechanisms of ageing and development 1988;42(2):173-81.
1988: E E Kousvelari; D K Banerjee; S R Grant; Bruce J Baum
Modulation of oligosaccharide processing in an exocrine secretory glycoprotein of rat parotid cells by beta-adrenoreceptor activation.
Archives of oral biology 1988;33(2):115-20.
1987: Joseph I Helman; Indu S Ambudkar; Bruce J Baum
Adrenoreceptor mobilization of calcium in rat submandibular cells.
European journal of pharmacology 1987;143(1):65-72.
1987: D K Banerjee; E E Kousvelari; Bruce J Baum
cAMP-mediated protein phosphorylation of microsomal membranes increases mannosylphosphodolichol synthase activity.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(18):6389-93.
1987: Yitzhak Marmary; Philip C Fox; Bruce J Baum
Fluid secretion rates from mouse and rat parotid glands are markedly different following pilocarpine stimulation.
Comparative biochemistry and physiology. A, Comparative physiology 1987;88(2):307-10.
1985: S R Grant; E E Kousvelari; D K Banerjee; Bruce J Baum
beta-Adrenergic stimulation alters oligosaccharide pyrophosphoryl dolichol metabolism in rat parotid acinar cells.
The Biochemical journal 1985;231(2):431-8.
1985: D K Banerjee; E E Kousvelari; Bruce J Baum
beta-Adrenergic activation of glycosyltransferases in the dolichylmonophosphate-linked pathway of protein N-glycosylation.
Biochemical and biophysical research communications 1985;126(1):123-9.
1984: E E Kousvelari; S R Grant; D K Banerjee; M J Newby; Bruce J Baum
Cyclic AMP mediates beta-adrenergic-induced increases in N-linked protein glycosylation in rat parotid acinar cells.
The Biochemical journal 1984;222(1):17-24.
1983: E E Kousvelari; S R Grant; Bruce J Baum
beta-Adrenergic receptor regulation of N-linked protein glycosylation in rat parotid acinar cells.
Proceedings of the National Academy of Sciences of the United States of America 1983;80(23):7146-50.
1983: E E Kousvelari; S R Grant; Bruce J Baum
Dolichyl phosphate supplementation increases N-linked protein glycosylation in rat parotid acinar cells without increasing glycoprotein secretion.
Experimental cell research 1983;149(1):271-6.