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James McCubrey

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Publications

TOP 3
Steelman Linda S; McCubrey James A
Intriguing novel abilities of Nutlin-3A: induction of cellular quiescence as opposed to cellular senescence--implications for chemotherapy.
Martelli Alberto M; Evangelisti Camilla; Chiarini Francesca; Grimaldi Cecilia; Manzoli Lucia; McCubrey James A
Targeting the PI3K/AKT/mTOR signaling network in acute myelogenous leukemia.
Sánchez Catherine; Mendoza Patricia; Contreras Héctor R; Vergara Jorge; McCubrey James A; Huidobro Christian; Castellón Enrique A
Expression of multidrug resistance proteins in prostate cancer is related with cell sensitivity to chemotherapeutic drugs.

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All Publications

2009: Steelman Linda S; McCubrey James A
Intriguing novel abilities of Nutlin-3A: induction of cellular quiescence as opposed to cellular senescence--implications for chemotherapy.
Cell cycle (Georgetown, Tex.) 2009;8(22):3634-5.
2009: Martelli Alberto M; Evangelisti Camilla; Chiarini Francesca; Grimaldi Cecilia; Manzoli Lucia; McCubrey James A
Targeting the PI3K/AKT/mTOR signaling network in acute myelogenous leukemia.
Expert opinion on investigational drugs 2009;18(9):1333-49.
2009: Sánchez Catherine; Mendoza Patricia; Contreras Héctor R; Vergara Jorge; McCubrey James A; Huidobro Christian; Castellón Enrique A
Expression of multidrug resistance proteins in prostate cancer is related with cell sensitivity to chemotherapeutic drugs.
The Prostate 2009;69(13):1448-59.
2009: Lampiasi Nadia; Azzolina Antonina; D'Alessandro Natale; Umezawa Kazuo; McCubrey James A; Montalto Giuseppe; Cervello Melchiorre
Antitumor effects of dehydroxymethylepoxyquinomicin, a novel nuclear factor-kappaB inhibitor, in human liver cancer cells are mediated through a reactive oxygen species-dependent mechanism.
Molecular pharmacology 2009;76(2):290-300.
2009: Franklin Richard A; McCubrey James A
The involvement of CaM-KII in insulin induced cell proliferation.
Cell cycle (Georgetown, Tex.) 2009;8(13):1979.
2009: Russo Alessia E; Torrisi Elena; Bevelacqua Ylenia; Perrotta Rosario; Libra Massimo; McCubrey James A; Spandidos Demetrios A; Stivala Franca; Malaponte Grazia
Melanoma: molecular pathogenesis and emerging target therapies (Review).
International journal of oncology 2009;34(6):1481-9.
2009: Castellano Giancarlo; Torrisi Elena; Ligresti Giovanni; Malaponte Grazia; Militello Loredana; Russo Alessia E; McCubrey James A; Canevari Silvana; Libra Massimo
The involvement of the transcription factor Yin Yang 1 in cancer development and progression.
Cell cycle (Georgetown, Tex.) 2009;8(9):1367-72.
2009: Cappellini Alessandra; Chiarini Francesca; Ognibene Andrea; McCubrey James A; Martelli Alberto M
The cyclin-dependent kinase inhibitor roscovitine and the nucleoside analog sangivamycin induce apoptosis in caspase-3 deficient breast cancer cells independent of caspase mediated P-glycoprotein cleavage: implications for therapy of drug resistant breast cancers.
Cell cycle (Georgetown, Tex.) 2009;8(9):1421-5.
2009: Ligresti Giovanni; Militello Loredana; Steelman Linda S; Cavallaro Andrea; Basile Francesco; Nicoletti Ferdinando; Stivala Franca; McCubrey James A; Libra Massimo
PIK3CA mutations in human solid tumors: role in sensitivity to various therapeutic approaches.
Cell cycle (Georgetown, Tex.) 2009;8(9):1352-8.
2009: Chiarini Francesca; Falà Federica; Tazzari Pier Luigi; Ricci Francesca; Astolfi Annalisa; Pession Andrea; Pagliaro Pasqualepaolo; McCubrey James A; Martelli Alberto M
Dual inhibition of class IA phosphatidylinositol 3-kinase and mammalian target of rapamycin as a new therapeutic option for T-cell acute lymphoblastic leukemia.
Cancer research 2009;69(8):3520-8.
2009: Konkimalla V Badireenath; McCubrey James A; Efferth Thomas
The role of downstream signaling pathways of the epidermal growth factor receptor for Artesunate's activity in cancer cells.
Current cancer drug targets 2009;9(1):72-80.
2009: Misaghian N; Ligresti G; Steelman L S; Bertrand F E; Bäsecke J; Libra M; Nicoletti F; Stivala F; Milella M; Tafuri A; Cervello M; Martelli A M; McCubrey J A
Targeting the leukemic stem cell: the Holy Grail of leukemia therapy.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2009;23(1):25-42.
2008: Tazzari Pier Luigi; Tabellini Giovanna; Ricci Francesca; Papa Veronica; Bortul Roberta; Chiarini Francesca; Evangelisti Camilla; Martinelli Giovanni; Bontadini Andrea; Cocco Lucio; McCubrey James A; Martelli Alberto M
Synergistic proapoptotic activity of recombinant TRAIL plus the Akt inhibitor Perifosine in acute myelogenous leukemia cells.
Cancer research 2008;68(22):9394-403.
2008: McCubrey J A; Abrams S L; Ligresti G; Misaghian N; Wong E W T; Steelman L S; Bäsecke J; Troppmair J; Libra M; Nicoletti F; Molton S; McMahon M; Evangelisti C; Martelli A M
Involvement of p53 and Raf/MEK/ERK pathways in hematopoietic drug resistance.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2008;22(11):2080-90.
2008: Long Jacquelyn M; Bell Charles W; Fagg W Samuel; Kushman Mary E; Becker Kevin G; McCubrey James A; Farwell Mary A
Microarray and pathway analysis reveals decreased CDC25A and increased CDC42 associated with slow growth of BCL2 overexpressing immortalized breast cell line.
Cell cycle (Georgetown, Tex.) 2008;7(19):3062-73.
2008: Lehmann Brian D; Paine Matthew S; Brooks Adam M; McCubrey James A; Renegar Randall H; Wang Rong; Terrian David M
Senescence-associated exosome release from human prostate cancer cells.
Cancer research 2008;68(19):7864-71.
2008: Steelman Linda S; Stadelman Kristin M; Chappell William H; Horn Stefan; Bäsecke Jörg; Cervello Melchiorre; Nicoletti Ferdinando; Libra Massimo; Stivala Franca; Martelli Alberto M; McCubrey James A
Akt as a therapeutic target in cancer.
Expert opinion on therapeutic targets 2008;12(9):1139-65.
2008: Falà Federica; Blalock William L; Tazzari Pier Luigi; Cappellini Alessandra; Chiarini Francesca; Martinelli Giovanni; Tafuri Agostino; McCubrey James A; Cocco Lucio; Martelli Alberto M
Proapoptotic activity and chemosensitizing effect of the novel Akt inhibitor (2S)-1-(1H-Indol-3-yl)-3-[5-(3-methyl-2H-indazol-5-yl)pyridin-3-yl]oxypropan2-amine (A443654) in T-cell acute lymphoblastic leukemia.
Molecular pharmacology 2008;74(3):884-95.
2008: McCubrey James A; Bäsecke Jörg; Cervello Melchiorre; Martelli Alberto M; Franklin Richard A
GSK-3beta is a critical mediator of tetrandrine induced cell cycle arrest and cytotoxicity.
Cancer biology & therapy 2008;7(7):1079.
2008: Steelman L S; Navolanic P M; Sokolosky M L; Taylor J R; Lehmann B D; Chappell W H; Abrams S L; Wong E W T; Stadelman K M; Terrian D M; Leslie N R; Martelli A M; Stivala F; Libra M; Franklin R A; McCubrey J A
Suppression of PTEN function increases breast cancer chemotherapeutic drug resistance while conferring sensitivity to mTOR inhibitors.
Oncogene 2008;27(29):4086-95.
2008: Lee John T; Lehmann Brian D; Terrian David M; Chappell William H; Stivala Franca; Libra Massimo; Martelli Alberto M; Steelman Linda S; McCubrey James A
Targeting prostate cancer based on signal transduction and cell cycle pathways.
Cell cycle (Georgetown, Tex.) 2008;7(12):1745-62.
2008: McCubrey James A; Milella Michele; Tafuri Agostino; Martelli Alberto M; Lunghi Paolo; Bonati Antonio; Cervello Melchiorre; Lee John T; Steelman Linda S
Targeting the Raf/MEK/ERK pathway with small-molecule inhibitors.
Current opinion in investigational drugs (London, England : 2000) 2008;9(6):614-30.
2008: Lehmann Brian D; Brooks Adam M; Paine Matthew S; Chappell William H; McCubrey James A; Terrian David M
Distinct roles for p107 and p130 in Rb-independent cellular senescence.
Cell cycle (Georgetown, Tex.) 2008;7(9):1262-8.
2008: Franklin Richard A; McCubrey James A
A multipronged approach to prostate cancer.
Cancer biology & therapy 2008;7(4):594-5.
2008: Steelman L S; Abrams S L; Whelan J; Bertrand F E; Ludwig D E; Bäsecke J; Libra M; Stivala F; Milella M; Tafuri A; Lunghi P; Bonati A; Martelli A M; McCubrey J A
Contributions of the Raf/MEK/ERK, PI3K/PTEN/Akt/mTOR and Jak/STAT pathways to leukemia.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2008;22(4):686-707.
2008: McCubrey J A; Steelman L S; Abrams S L; Bertrand F E; Ludwig D E; Bäsecke J; Libra M; Stivala F; Milella M; Tafuri A; Lunghi P; Bonati A; Martelli A M
Targeting survival cascades induced by activation of Ras/Raf/MEK/ERK, PI3K/PTEN/Akt/mTOR and Jak/STAT pathways for effective leukemia therapy.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2008;22(4):708-22.
2008: Zhang W; Konopleva M; Ruvolo V R; McQueen T; Evans R L; Bornmann W G; McCubrey J; Cortes J; Andreeff M
Sorafenib induces apoptosis of AML cells via Bim-mediated activation of the intrinsic apoptotic pathway.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2008;22(4):808-18.
2008: Lee John T; Steelman Linda S; Chappell William H; McCubrey James A
Akt inactivates ERK causing decreased response to chemotherapeutic drugs in advanced CaP cells.
Cell cycle (Georgetown, Tex.) 2008;7(5):631-6.
2008: McCubrey James A; Sokolosky Melissa L; Lehmann Brian D; Taylor Jackson R; Navolanic Patrick M; Chappell William H; Abrams Stephen L; Stadelman Kristin M; Wong Ellis W T; Misaghian Negin; Horn Stefan; Bäsecke Jörg; Libra Massimo; Stivala Franca; Ligresti Giovanni; Tafuri Agostino; Milella Michele; Zarzycki Marek; Dzugaj Andrzej; Chiarini Francesca; Evangelisti Camilla; Martelli Alberto M; Terrian David M; Franklin Richard A; Steelman Linda S
Alteration of Akt activity increases chemotherapeutic drug and hormonal resistance in breast cancer yet confers an achilles heel by sensitization to targeted therapy.
Advances in enzyme regulation 2008;48():113-35.
2007: McCubrey James A; Steelman Linda S; Chappell William H; Abrams Stephen L; Wong Ellis W T; Chang Fumin; Lehmann Brian; Terrian David M; Milella Michele; Tafuri Agostino; Stivala Franca; Libra Massimo; Basecke Jorg; Evangelisti Camilla; Martelli Alberto M; Franklin Richard A
Roles of the Raf/MEK/ERK pathway in cell growth, malignant transformation and drug resistance.
Biochimica et biophysica acta 2007;1773(8):1263-84.
2007: Tortora Giampaolo; Bianco Roberto; Daniele Gennaro; Ciardiello Fortunato; McCubrey James A; Ricciardi Maria Rosaria; Ciuffreda Ludovica; Cognetti Francesco; Tafuri Agostino; Milella Michele
Overcoming resistance to molecularly targeted anticancer therapies: Rational drug combinations based on EGFR and MAPK inhibition for solid tumours and haematologic malignancies.
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2007;10(3):81-100.
2007: Lambert Phelps J; Shahrier Aniqa Z; Whitman Audy G; Dyson Ossie F; Reber Adrian J; McCubrey James A; Akula Shaw M
Targeting the PI3K and MAPK pathways to treat Kaposi's-sarcoma-associated herpes virus infection and pathogenesis.
Expert opinion on therapeutic targets 2007;11(5):589-99.
2007: Lehmann Brian D; McCubrey James A; Jefferson Holly S; Paine Matthew S; Chappell William H; Terrian David M
A dominant role for p53-dependent cellular senescence in radiosensitization of human prostate cancer cells.
Cell cycle (Georgetown, Tex.) 2007;6(5):595-605.
2007: Franklin Richard A; McCubrey James A
Polyphenols in breast cancer treatment.
Cancer biology & therapy 2007;6(1):62-3.
2007: Knostman Katherine A B; McCubrey James A; Morrison Carl D; Zhang Zhaoxia; Capen Charles C; Jhiang Sissy M
PI3K activation is associated with intracellular sodium/iodide symporter protein expression in breast cancer.
BMC cancer 2007;7():137.
2007: McCubrey James A; Steelman Linda S; Franklin Richard A; Abrams Steven L; Chappell William H; Wong Ellis W T; Lehmann Brian D; Terrian David M; Basecke Jorg; Stivala Franca; Libra Massimo; Evangelisti Camilla; Martelli Alberto M
Targeting the RAF/MEK/ERK, PI3K/AKT and p53 pathways in hematopoietic drug resistance.
Advances in enzyme regulation 2007;47():64-103.
2006: Garcia Ruben; Franklin Richard A; McCubrey James A
EGF induces cell motility and multi-drug resistance gene expression in breast cancer cells.
Cell cycle (Georgetown, Tex.) 2006;5(23):2820-6.
2006: Konopleva Marina; Contractor Rooha; Tsao Twee; Samudio Ismael; Ruvolo Peter P; Kitada Shinichi; Deng Xingming; Zhai Dayong; Shi Yue-Xi; Sneed Thomas; Verhaegen Monique; Soengas Maria; Ruvolo Vivian R; McQueen Teresa; Schober Wendy D; Watt Julie C; Jiffar Tilahun; Ling Xiaoyang; Marini Frank C; Harris David; Dietrich Martin; Estrov Zeev; McCubrey James; May W Stratford; Reed John C; Andreeff Michael
Mechanisms of apoptosis sensitivity and resistance to the BH3 mimetic ABT-737 in acute myeloid leukemia.
Cancer cell 2006;10(5):375-88.
2006: Franklin Richard A; Rodriguez-Mora Oswaldo G; Lahair Michelle M; McCubrey James A
Activation of the calcium/calmodulin-dependent protein kinases as a consequence of oxidative stress.
Antioxidants & redox signaling 2006;8(9-10):1807-17.
2006: McCubrey James A; Lahair Michelle M; Franklin Richard A
Reactive oxygen species-induced activation of the MAP kinase signaling pathways.
Antioxidants & redox signaling 2006;8(9-10):1775-89.
2006: Lahair Michelle M; Howe Christopher J; Rodriguez-Mora Oswaldo; McCubrey James A; Franklin Richard A
Molecular pathways leading to oxidative stress-induced phosphorylation of Akt.
Antioxidants & redox signaling 2006;8(9-10):1749-56.
2006: McCubrey James A; Franklin Richard A
Reactive oxygen intermediates and signaling through kinase pathways.
Antioxidants & redox signaling 2006;8(9-10):1745-8.
2006: Garcia Ruben; Franklin Richard A; McCubrey James A
Cell death of MCF-7 human breast cancer cells induced by EGFR activation in the absence of other growth factors.
Cell cycle (Georgetown, Tex.) 2006;5(16):1840-6.
2006: Rodriguez-Mora Oswaldo G; Lahair Michelle M; Evans Mark J; Kovacs Charles J; Allison Ron R; Sibata Claudio H; White Kawana S; McCubrey James A; Franklin Richard A
Inhibition of the CaM-kinases augments cell death in response to oxygen radicals and oxygen radical inducing cancer therapies in MCF-7 human breast cancer cells.
Cancer biology & therapy 2006;5(8):1022-30.
2006: McCubrey James A; Lahair Michelle M; Franklin Richard A
OSU-03012 in the treatment of glioblastoma.
Molecular pharmacology 2006;70(2):437-9.
2006: Bertrand F E; Steelman L S; Chappell W H; Abrams S L; Shelton J G; White E R; Ludwig D L; McCubrey J A
Synergy between an IGF-1R antibody and Raf/MEK/ERK and PI3K/Akt/mTOR pathway inhibitors in suppressing IGF-1R-mediated growth in hematopoietic cells.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2006;20(7):1254-60.
2006: Libra Massimo; Malaponte Grazia; Bevelacqua Valentina; Siciliano Roberta; Castrogiovanni Paola; Fulvi Alberto; Micali Giuseppe; Ligresti Giovanni; Mazzarino Maria C; Stivala Franca; Travali Salvatore; McCubrey James A
Absence of BRAF gene mutation in non-melanoma skin tumors.
Cell cycle (Georgetown, Tex.) 2006;5(9):968-70.
2006: Malaponte Grazia; Libra Massimo; Gangemi Pietro; Bevelacqua Valentina; Mangano Katia; D'Amico Fabio; Mazzarino Maria C; Stivala Franca; McCubrey James A; Travali Salvatore
Detection of BRAF gene mutation in primary choroidal melanoma tissue.
Cancer biology & therapy 2006;5(2):225-7.
2006: Indelicato Manuela; Chiarenza Valentina; Libra Massimo; Malaponte Grazia; Bevelacqua Valentina; Marchini Maurizio; McCubrey James A; Stivala Franca; Scorza Raffaella; Mazzarino Maria Clorinda
Analysis of TIMP-1 gene polymorphisms in Italian sclerodermic patients.
Journal of clinical laboratory analysis 2006;20(5):173-6.
2006: McCubrey James A; Steelman Linda S; Abrams Steven L; Lee John T; Chang Fumin; Bertrand Fred E; Navolanic Patrick M; Terrian David M; Franklin Richard A; D'Assoro Antonio B; Salisbury Jeffrey L; Mazzarino Maria Clorinda; Stivala Franca; Libra Massimo
Roles of the RAF/MEK/ERK and PI3K/PTEN/AKT pathways in malignant transformation and drug resistance.
Advances in enzyme regulation 2006;46():249-79.
2005: Ford Patrick W; Hamden Khalief E; Whitman Audy G; Bryan Benjaman A; Chintalgattu Vishnu; McCubrey James A; Dyson Ossie F; Akula Shaw M
Cigarette smoke concentrate inhibits Kaposi's sarcoma-associated herpesvirus infection.
Virus research 2005;114(1-2):172-6.
2005: Franklin Richard A; Libra Massimo; Stivala Franca; McCubrey James A
Two targets are better than one. Promising combination therapy to treat breast cancer.
Cancer biology & therapy 2005;4(11):1190-1.
2005: Konopleva Marina; Shi Yuexi; Steelman Linda S; Shelton John G; Munsell Mark; Marini Frank; McQueen Teresa; Contractor Rooha; McCubrey James A; Andreeff Michael
Development of a conditional in vivo model to evaluate the efficacy of small molecule inhibitors for the treatment of Raf-transformed hematopoietic cells.
Cancer research 2005;65(21):9962-70.
2005: Navolanic Patrick M; McCubrey James A
Pharmacological breast cancer therapy (review).
International journal of oncology 2005;27(5):1341-4.
2005: Libra Massimo; Indelicato Manuela; De Re Vallì; Zignego Anna Linda; Chiocchetti Annalisa; Malaponte Grazia; Dianzani Umberto; Nicoletti Ferdinando; Stivala Franca; McCubrey James A; Mazzarino Maria C
Elevated Serum Levels of Osteopontin in HCV-Associated Lymphoproliferative Disorders.
Cancer biology & therapy 2005;4(11):1192-4.
2005: Asano Takayuki; Yao Yixin; Shin Sonyo; McCubrey James; Abbruzzese James L; Reddy Shrikanth A G
Insulin receptor substrate is a mediator of phosphoinositide 3-kinase activation in quiescent pancreatic cancer cells.
Cancer research 2005;65(20):9164-8.
2005: Shelton John G; Steelman Linda S; Abrams Steve L; Bertrand Fred E; Franklin Richard A; McMahon Martin; McCubrey James A
The epidermal growth factor receptor gene family as a target for therapeutic intervention in numerous cancers: what's genetics got to do with it?
Expert opinion on therapeutic targets 2005;9(5):1009-30.
2005: Libra Massimo; Malaponte Grazia; Navolanic Patrick M; Gangemi Pietro; Bevelacqua Valentina; Proietti Lidia; Bruni Bibiana; Stivala Franca; Mazzarino Maria C; Travali Salvatore; McCubrey James A
Analysis of BRAF mutation in primary and metastatic melanoma.
Cell cycle (Georgetown, Tex.) 2005;4(10):1382-4.
2005: Chappell William H; Green Thomas D; Spengeman Justin D; McCubrey James A; Akula Shaw M; Bertrand Fred E
Increased protein expression of the PTEN tumor suppressor in the presence of constitutively active Notch-1.
Cell cycle (Georgetown, Tex.) 2005;4(10):1389-95.
2005: Rodriguez-Mora Oswaldo; LaHair Michelle M; Howe Christopher J; McCubrey James A; Franklin Richard A
Calcium/calmodulin-dependent protein kinases as potential targets in cancer therapy.
Expert opinion on therapeutic targets 2005;9(4):791-808.
2005: Rodriguez-Mora Oswaldo G; LaHair Michelle M; McCubrey James A; Franklin Richard A
Calcium/calmodulin-dependent kinase I and calcium/calmodulin-dependent kinase kinase participate in the control of cell cycle progression in MCF-7 human breast cancer cells.
Cancer research 2005;65(12):5408-16.
2005: Shelton John G; Steelman Linda S; Abrams Steven L; White Edmund R; Akula Shaw M; Franklin Richard A; Bertrand Fred E; McMahon Martin; McCubrey James A
Conditional EGFR promotes cell cycle progression and prevention of apoptosis in the absence of autocrine cytokines.
Cell cycle (Georgetown, Tex.) 2005;4(6):822-30.
2005: Rodriguez-Mora Oswaldo G; Howe Christopher J; Lahair Michelle M; McCubrey James A; Franklin Richard A
Inhibition of CREB transcriptional activity in human T lymphocytes by oxidative stress.
Free radical biology & medicine 2005;38(12):1653-61.
2005: Shelton John G; Steelman Linda S; Abrams Steven L; White Edmund R; Akula Shaw M; Bertrand Fred E; Franklin Richard A; McCubrey James A
Effects of endogenous epidermal growth factor receptor signaling on DNA synthesis and ERK activation in a cytokine-dependent hematopoietic cell line.
Cell cycle (Georgetown, Tex.) 2005;4(6):818-21.
2005: Lee John T; Steelman Linda S; McCubrey James A
Modulation of Raf/MEK/ERK kinase activity does not affect the chemoresistance profile of advanced prostate cancer cells.
International journal of oncology 2005;26(6):1637-44.
2005: Akula Shaw M; Ford Patrick W; Whitman Audy G; Hamden Khalief E; Bryan Benjaman A; Cook Paul P; McCubrey James A
B-Raf-dependent expression of vascular endothelial growth factor-A in Kaposi sarcoma-associated herpesvirus-infected human B cells.
Blood 2005;105(11):4516-22.
2005: McCubrey James A; Bertrand Fred E
Upping the bid on engineered inducible cell death.
Cancer biology & therapy 2005;4(5):537.
2005: Demidenko Zoya N; Halicka Dorota; Kunicki Jan; McCubrey James A; Darzynkiewicz Zbigniew; Blagosklonny Mikhail V
Selective killing of adriamycin-resistant (G2 checkpoint-deficient and MRP1-expressing) cancer cells by docetaxel.
Cancer research 2005;65(10):4401-7.
2005: Demidenko Zoya N; An Won G; Lee John T; Romanova Larisa Y; McCubrey James A; Blagosklonny Mikhail V
Kinase-addiction and bi-phasic sensitivity-resistance of Bcr-Abl- and Raf-1-expressing cells to imatinib and geldanamycin.
Cancer biology & therapy 2005;4(4):484-90.
2005: Contractor Rooha; Samudio Ismael J; Estrov Zeev; Harris David; McCubrey James A; Safe Stephen H; Andreeff Michael; Konopleva Marina
A novel ring-substituted diindolylmethane,1,1-bis[3'-(5-methoxyindolyl)]-1-(p-t-butylphenyl) methane, inhibits extracellular signal-regulated kinase activation and induces apoptosis in acute myelogenous leukemia.
Cancer research 2005;65(7):2890-8.
2005: Spengeman Justin D; Green Thomas D; McCubrey James A; Bertrand Fred E
Activated EGFR promotes the survival of B-lineage acute leukemia in the absence of stromal cells.
Cell cycle (Georgetown, Tex.) 2005;4(3):483-7.
2005: Calfee M Worth; Shelton John G; McCubrey James A; Pesci Everett C
Solubility and bioactivity of the Pseudomonas quinolone signal are increased by a Pseudomonas aeruginosa-produced surfactant.
Infection and immunity 2005;73(2):878-82.
2005: Bertrand F E; Spengemen J D; Shelton J G; McCubrey J A
Inhibition of PI3K, mTOR and MEK signaling pathways promotes rapid apoptosis in B-lineage ALL in the presence of stromal cell support.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2005;19(1):98-102.
2005: Hamden K E; Whitman A G; Ford P W; Shelton J G; McCubrey J A; Akula S M
Raf and VEGF: emerging therapeutic targets in Kaposi's sarcoma-associated herpesvirus infection and angiogenesis in hematopoietic and nonhematopoietic tumors.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2005;19(1):18-26.
2005: Bertrand Fred E; McCubrey James A
Acquired immunodeficiency syndrome associated lymphoma.
Frontiers in bioscience : a journal and virtual library 2005;10():2972-7.
2005: Bryan Benjaman A; Dyson Ossie F; McCubrey James A; Akula Shaw M
Biology of Kaposi's sarcoma-associated herpesvirus.
Frontiers in bioscience : a journal and virtual library 2005;10():2882-91.
2004: Steelman Linda S; Bertrand Fred E; McCubrey James A
The complexity of PTEN: mutation, marker and potential target for therapeutic intervention.
Expert opinion on therapeutic targets 2004;8(6):537-50.
2004: Hamden Khalief E; Ford Patrick W; Whitman Audy G; Dyson Ossie F; Cheng Shi-Yuan; McCubrey James A; Akula Shaw M
Raf-induced vascular endothelial growth factor augments Kaposi's sarcoma-associated herpesvirus infection.
Journal of virology 2004;78(23):13381-90.
2004: Lee John T; Steelman Linda S; McCubrey James A
Phosphatidylinositol 3'-kinase activation leads to multidrug resistance protein-1 expression and subsequent chemoresistance in advanced prostate cancer cells.
Cancer research 2004;64(22):8397-404.
2004: Wu Daqing; Thakore Chittam U; Wescott Ginger G; McCubrey James A; Terrian David M
Integrin signaling links protein kinase Cepsilon to the protein kinase B/Akt survival pathway in recurrent prostate cancer cells.
Oncogene 2004;23(53):8659-72.
2004: Knostman Katherine A B; Cho Je-Yoel; Ryu Kwon-Yul; Lin Xiaoqin; McCubrey James A; Hla Timothy; Liu Catherine H; Di Carlo Emma; Keri Ruth; Zhang Ming; Hwang Dae Y; Kisseberth William C; Capen Charles C; Jhiang Sissy M
Signaling through 3',5'-cyclic adenosine monophosphate and phosphoinositide-3 kinase induces sodium/iodide symporter expression in breast cancer.
The Journal of clinical endocrinology and metabolism 2004;89(10):5196-203.
2004: McCubrey James A; Shelton John G; Steelman Linda S; Franklin Richard A; Sreevalsan Thazepadath; McMahon Martin
Effects of a conditionally active v-ErbB and an EGF-R inhibitor on transformation of NIH-3T3 cells and abrogation of cytokine dependency of hematopoietic cells.
Oncogene 2004;23(47):7810-20.
2004: Howe Christopher J; Lahair Michelle M; McCubrey James A; Franklin Richard A
Redox regulation of the calcium/calmodulin-dependent protein kinases.
The Journal of biological chemistry 2004;279(43):44573-81.
2004: Ford Patrick W; Hamden Khalief E; Whitman Audy G; McCubrey James A; Akula Shaw M
Vascular endothelial growth factor augments human herpesvirus-8 (HHV-8/KSHV) infection.
Cancer biology & therapy 2004;3(9):876-81.
2004: Whitman Audy G; Hamden Khalief E; Ford Patrick W; McCubrey James A; Akula Shaw M
Role for Raf in the entry of viruses associated with AIDS (review).
International journal of oncology 2004;25(2):469-80.
2004: Akula Shaw M; Ford Patrick W; Whitman Audy G; Hamden Khalief E; Shelton John G; McCubrey James A
Raf promotes human herpesvirus-8 (HHV-8/KSHV) infection.
Oncogene 2004;23(30):5227-41.
2004: Shelton John G; Blalock William L; White Edmond R; Steelman Linda S; McCubrey James A
Ability of the activated PI3K/Akt oncoproteins to synergize with MEK1 and induce cell cycle progression and abrogate the cytokine-dependence of hematopoietic cells.
Cell cycle (Georgetown, Tex.) 2004;3(4):503-12.
2004: Shelton John G; Steelman Linda S; White Edmond R; McCubrey James A
Synergy between PI3K/Akt and Raf/MEK/ERK pathways in IGF-1R mediated cell cycle progression and prevention of apoptosis in hematopoietic cells.
Cell cycle (Georgetown, Tex.) 2004;3(3):372-9.
2004: Navolanic Patrick M; Akula Shaw M; McCubrey James A
Neosis and its potential role in cancer development and chemoresistance.
Cancer biology & therapy 2004;3(2):219-20.
2004: Steelman L S; Pohnert S C; Shelton J G; Franklin R A; Bertrand F E; McCubrey J A
JAK/STAT, Raf/MEK/ERK, PI3K/Akt and BCR-ABL in cell cycle progression and leukemogenesis.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2004;18(2):189-218.
2004: Shelton John G; Chang Fumin; Lee John T; Franklin Richard A; Steelman Linda S; McCubrey James A
B-raf and insulin synergistically prevent apoptosis and induce cell cycle progression in hematopoietic cells.
Cell cycle (Georgetown, Tex.) 2004;3(2):189-96.
2004: Andreeff M; Milella M; Carter B Z; Tabe Y; Ricciardi M R; Sneed T; Ruvolo P; Contractor R; Tsao T; Schober W; Evans R; McQueen T; Zeng Z; Kornblau S M; McCubrey J; Estey E; Mills G B; Reed J C; Konopleva M
Targeted therapy of AML new concepts.
Annals of hematology 2004;83 Suppl 1():S51-3.
2003: Navolanic Patrick M; Lee John T; McCubrey James A
Docetaxel cytotoxicity is enhanced by inhibition of the Raf/MEK/ERK signal transduction pathway.
Cancer biology & therapy 2003;2(6):677-8.
2003: Carter B Z; Milella M; Tsao T; McQueen T; Schober W D; Hu W; Dean N M; Steelman L; McCubrey J A; Andreeff M
Regulation and targeting of antiapoptotic XIAP in acute myeloid leukemia.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2003;17(11):2081-9.
2003: Shelton J G; Moye P W; Steelman L S; Blalock W L; Lee J T; Franklin R A; McMahon M; McCubrey J A
Differential effects of kinase cascade inhibitors on neoplastic and cytokine-mediated cell proliferation.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2003;17(9):1765-82.
2003: Howe Christopher J; LaHair Michelle M; Robinson Penni J; Rodriguez-Mora Oswaldo; McCubrey James A; Franklin Richard A
Models of anergy in the human Jurkat T cell line.
Assay and drug development technologies 2003;1(4):537-44.
2003: Rodriguez-Mora Oswaldo; Franklin Richard A; McCubrey James A
A new hope for treatment of glioblastomas.
Cancer biology & therapy 2003;2(4):354-5.
2003: Chang F; Steelman L S; Lee J T; Shelton J G; Navolanic P M; Blalock W L; Franklin R A; McCubrey J A
Signal transduction mediated by the Ras/Raf/MEK/ERK pathway from cytokine receptors to transcription factors: potential targeting for therapeutic intervention.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2003;17(7):1263-93.
2003: Lee John T; McCubrey James A
BAY-43-9006 Bayer/Onyx.
Current opinion in investigational drugs (London, England : 2000) 2003;4(6):757-63.
2003: Blalock W L; Navolanic P M; Steelman L S; Shelton J G; Moye P W; Lee J T; Franklin R A; Mirza A; McMahon M; White M K; McCubrey J A
Requirement for the PI3K/Akt pathway in MEK1-mediated growth and prevention of apoptosis: identification of an Achilles heel in leukemia.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2003;17(6):1058-67.
2003: Shelton John G; Steelman Linda S; Lee John T; Knapp Steven L; Blalock William L; Moye Phillip W; Franklin Richard A; Pohnert Steven C; Mirza Amer M; McMahon Martin; McCubrey James A
Effects of the RAF/MEK/ERK and PI3K/AKT signal transduction pathways on the abrogation of cytokine-dependence and prevention of apoptosis in hematopoietic cells.
Oncogene 2003;22(16):2478-92.
2003: Chang F; Lee J T; Navolanic P M; Steelman L S; Shelton J G; Blalock W L; Franklin R A; McCubrey J A
Involvement of PI3K/Akt pathway in cell cycle progression, apoptosis, and neoplastic transformation: a target for cancer chemotherapy.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2003;17(3):590-603.
2003: Navolanic P M; Pui C-H; Larson R A; Bishop M R; Pearce T E; Cairo M S; Goldman S C; Jeha S C; Shanholtz C B; Leonard J P; McCubrey J A
Elitek-rasburicase: an effective means to prevent and treat hyperuricemia associated with tumor lysis syndrome, a Meeting Report, Dallas, Texas, January 2002.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2003;17(3):499-514.
2003: Davis Julianne M; Navolanic Patrick M; Weinstein-Oppenheimer Caroline R; Steelman Linda S; Hu Wei; Konopleva Marina; Blagosklonny Mikhail V; McCubrey James A
Raf-1 and Bcl-2 induce distinct and common pathways that contribute to breast cancer drug resistance.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(3):1161-70.
2003: Chang Fumin; Steelman Linda S; Shelton John G; Lee John T; Navolanic Patrick M; Blalock William L; Franklin Richard; McCubrey James A
Regulation of cell cycle progression and apoptosis by the Ras/Raf/MEK/ERK pathway (Review).
International journal of oncology 2003;22(3):469-80.
2003: Navolanic Patrick M; Steelman Linda S; McCubrey James A
EGFR family signaling and its association with breast cancer development and resistance to chemotherapy (Review).
International journal of oncology 2003;22(2):237-52.
2003: Steelman Linda S; Blalock William L; Wang Xiao-Yang; Moye Phillip W; Lee John T; Shelton John G; Navolanic Patrick M; Davis Julianne M; Knapp Steven L; Franklin Richard A; White Martyn K; McCubrey James A
Elucidation of signal transduction pathways by retroviral infection of cells with modified oncogenes.
Methods in molecular biology (Clifton, N.J.) 2003;218():221-52.
2003: Steelman Linda S; Blalock William L; Wang Xiao-Yang; Moye Phillip W; Lee John T; Shelton John G; Navolanic Patrick M; Davis Julianne M; Knapp Steven L; Franklin Richard A; White Martyn K; McCubrey James A
Elucidation of signal transduction pathways by transfection of cells with modified oncogenes.
Methods in molecular biology (Clifton, N.J.) 2003;218():203-20.
2003: Steelman Linda S; Blalock William L; Wang Xiao-Yang; Moye Phillip W; Lee John T; Shelton John G; Navolanic Patrick M; Davis Julianne M; Knapp Steven L; Franklin Richard A; White Martyn K; McCubrey James A
Fibroblastic, hematopoietic, and hormone responsive epithelial cell lines and culture conditions for elucidation of signal transduction and drug resistance pathways by gene transfer.
Methods in molecular biology (Clifton, N.J.) 2003;218():185-201.
2002: Lee John T; McCubrey James A
Targeting the Raf kinase cascade in cancer therapy--novel molecular targets and therapeutic strategies.
Expert opinion on therapeutic targets 2002;6(6):659-78.
2002: Saleh Oussama A; Blalock William L; Burrows Carla; Steelman Linda S; Doshi Parul D; McKearn John P; McCubrey James A
Enhanced ability of the progenipoietin-1 to suppress apoptosis in human hematopoietic cells.
International journal of molecular medicine 2002;10(4):385-94.
2002: Howe Christopher J; LaHair Michelle M; Maxwell Jill A; Lee John T; Robinson Penni J; Rodriguez-Mora Oswaldo; McCubrey James A; Franklin Richard A
Participation of the calcium/calmodulin-dependent kinases in hydrogen peroxide-induced Ikappa B phosphorylation in human T lymphocytes.
The Journal of biological chemistry 2002;277(34):30469-76.
2002: Weinstein-Oppenheimer Caroline R; Burrows Carlo; Steelman Linda S; McCubrey James A
The effects of beta-estradiol on Raf activity, cell cycle progression and growth factor synthesis in the MCF-7 breast cancer cell line.
Cancer biology & therapy 2002;1(3):256-62.
2002: Chang Fumin; Steelman Linda S; McCubrey James A
Raf-induced cell cycle progression in human TF-1 hematopoietic cells.
Cell cycle (Georgetown, Tex.) 2002;1(3):220-6.
2002: Lee J T; McCubrey J A
The Raf/MEK/ERK signal transduction cascade as a target for chemotherapeutic intervention in leukemia.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2002;16(4):486-507.
2001: Weinstein-Oppenheimer C R; Henríquez-Roldán C F; Davis J M; Navolanic P M; Saleh O A; Steelman L S; Franklin R A; Robinson P J; McMahon M; McCubrey J A
Role of the Raf signal transduction cascade in the in vitro resistance to the anticancer drug doxorubicin.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(9):2898-907.
2001: McCubrey J A; Blalock W L; Saleh O; Pearce M; Burrows C; Steelman L S; Lee J T; Franklin R A; Oberhaus S M; Moye P W; Doshi P D; McKearn J P
Enhanced ability of daniplestim and myelopoietin-1 to suppress apoptosis in human hematopoietic cells.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2001;15(8):1203-16.
2001: Chang F; McCubrey J A
P21(Cip1) induced by Raf is associated with increased Cdk4 activity in hematopoietic cells.
Oncogene 2001;20(32):4354-64.
2001: Blalock W L; Pearce M; Chang F; Lee J T; Pohnert S C; Burrows C; Steelman L S; Franklin R A; McMahon M; McCubrey J A
Effects of inducible MEK1 activation on the cytokine dependency of lymphoid cells.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2001;15(5):794-807.
2001: McCubrey J A; Lee J T; Steelman L S; Blalock W L; Moye P W; Chang F; Pearce M; Shelton J G; White M K; Franklin R A; Pohnert S C
Interactions between the PI3K and Raf signaling pathways can result in the transformation of hematopoietic cells.
Cancer detection and prevention 2001;25(4):375-93.
2001: McCubrey J A; Steelman L S; Blalock W L; Lee J T; Moye P W; Chang F; Pearce M; Shelton J G; White M K; Franklin R A; Pohnert S C
Synergistic effects of pi3k/akt on abrogation of cytokine-dependency induced by oncogenic raf.
Advances in enzyme regulation 2001;41():289-323.
2000: Weinstein-Oppenheimer C R; Blalock W L; Steelman L S; Chang F; McCubrey J A
The Raf signal transduction cascade as a target for chemotherapeutic intervention in growth factor-responsive tumors.
Pharmacology & therapeutics 2000;88(3):229-79.
2000: Franklin R A; McCubrey J A
Kinases: positive and negative regulators of apoptosis.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2000;14(12):2019-34.
2000: Weinstein-Oppenheimer C; Steelman L S; Algate P A; Blalock W L; Burrows C; Hoyle P E; Lee J T; Moye P W; Shelton J G; Franklin R; McCubrey J A
Effects of deregulated Raf activation on integrin, cytokine-receptor expression and the induction of apoptosis in hematopoietic cells.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2000;14(11):1921-38.
2000: Franklin R A; Atherfold P A; McCubrey J A
Calcium-induced ERK activation in human T lymphocytes occurs via p56(Lck) and CaM-kinase.
Molecular immunology 2000;37(11):675-83.
2000: Blalock W L; Moye P W; Chang F; Pearce M; Steelman L S; McMahon M; McCubrey J A
Combined effects of aberrant MEK1 activity and BCL2 overexpression on relieving the cytokine dependency of human and murine hematopoietic cells.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2000;14(6):1080-96.
2000: Moye P W; Blalock W L; Hoyle P E; Chang F; Franklin R A; Weinstein-Oppenheimer C; Pearce M; Steelman L; McMahon M; McCubrey J A
Synergy between Raf and BCL2 in abrogating the cytokine dependency of hematopoietic cells.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2000;14(6):1060-79.
2000: Hoyle P E; Moye P W; Steelman L S; Blalock W L; Franklin R A; Pearce M; Cherwinski H; Bosch E; McMahon M; McCubrey J A
Differential abilities of the Raf family of protein kinases to abrogate cytokine dependency and prevent apoptosis in murine hematopoietic cells by a MEK1-dependent mechanism.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2000;14(4):642-56.
2000: Blalock W L; Pearce M; Steelman L S; Franklin R A; McCarthy S A; Cherwinski H; McMahon M; McCubrey J A
A conditionally-active form of MEK1 results in autocrine tranformation of human and mouse hematopoietic cells.
Oncogene 2000;19(4):526-36.
2000: McCubrey J A; May W S; Duronio V; Mufson A
Serine/threonine phosphorylation in cytokine signal transduction.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2000;14(1):9-21.
2000: McCubrey J A; Steelman L S; Moye P W; Hoyle P E; Weinstein-Oppenheimer C; Chang F; Pearce M; White M K; Franklin R; Blalock W L
Effects of deregulated RAF and MEK1 expression on the cytokine-dependency of hematopoietic cells.
Advances in enzyme regulation 2000;40():305-37.
1999: Blalock W L; Weinstein-Oppenheimer C; Chang F; Hoyle P E; Wang X Y; Algate P A; Franklin R A; Oberhaus S M; Steelman L S; McCubrey J A
Signal transduction, cell cycle regulatory, and anti-apoptotic pathways regulated by IL-3 in hematopoietic cells: possible sites for intervention with anti-neoplastic drugs.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1999;13(8):1109-66.
1998: McCubrey J A; Steelman L S; Hoyle P E; Blalock W L; Weinstein-Oppenheimer C; Franklin R A; Cherwinski H; Bosch E; McMahon M
Differential abilities of activated Raf oncoproteins to abrogate cytokine dependency, prevent apoptosis and induce autocrine growth factor synthesis in human hematopoietic cells.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1998;12(12):1903-29.
1998: Wang X Y; Hoyle P E; McCubrey J A
Characterization of proteins binding the 3' regulatory region of the IL-3 gene in IL-3-dependent and autocrine-transformed hematopoietic cells.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1998;12(4):520-31.
1997: Wang X Y; McCubrey J A
Differential effects of retroviral long terminal repeats on interleukin-3 gene expression and autocrine transformation.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1997;11(10):1711-25.
1997: Hoyle P E; Steelman L S; McCubrey J A
Autocrine transformation of human hematopoietic cells after transfection with an activated granulocyte/macrophage colony stimulating factor gene.
Cytokines, cellular & molecular therapy 1997;3(3):159-68.
1997: Wang X Y; Steelman L S; McCubrey J A
Abnormal activation of cytokine gene expression by intracisternal type A particle transposition: effects of mutations that result in autocrine growth stimulation and malignant transformation.
Cytokines, cellular & molecular therapy 1997;3(1):3-19.
1996: Wang X Y; McCubrey J A
Malignant transformation induced by cytokine genes: a comparison of the abilities of germline and mutated interleukin 3 genes to transform hematopoietic cells by transcriptional and posttranscriptional mechanisms.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1996;7(4):487-500.
1996: Steelman L S; Algate P A; Blalock W L; Wang X Y; Prevost K D; Hoyle P E; McCubrey J A
Oncogenic effects of overexpression of the interleukin-3 receptor on hematopoietic cells.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1996;10(3):528-42.
1995: Mayo M W; Wang X Y; Algate P A; Arana G F; Hoyle P E; Steelman L S; McCubrey J A
Synergy between AUUUA motif disruption and enhancer insertion results in autocrine transformation of interleukin-3-dependent hematopoietic cells.
Blood 1995;86(8):3139-50.
1994: Mayo M W; Steelman L S; McCubrey J A
Phorbol esters support the proliferation of a hematopoietic cell line by upregulating c-jun expression.
Oncogene 1994;9(7):1999-2008.
1994: Algate P A; Steelman L S; Mayo M W; Miyajima A; McCubrey J A
Regulation of the interleukin-3 (IL-3) receptor by IL-3 in the fetal liver-derived FL5.12 cell line.
Blood 1994;83(9):2459-68.
1993: McCubrey J A; Smith S R; Algate P A; DeVente J E; White M K; Steelman L S
Retroviral infection can abrogate the factor-dependency of hematopoietic cells by autocrine and non-autocrine mechanisms depending on the presence of a functional viral oncogene.
Oncogene 1993;8(11):2905-15.
1993: Algate P A; McCubrey J A
Autocrine transformation of hemopoietic cells resulting from cytokine message stabilization after intracisternal A particle transposition.
Oncogene 1993;8(5):1221-32.
1993: Buttke T M; McCubrey J A; Owen T C
Use of an aqueous soluble tetrazolium/formazan assay to measure viability and proliferation of lymphokine-dependent cell lines.
Journal of immunological methods 1993;157(1-2):233-40.
1991: Ways D K; Qin W; Riddle R S; Garris T D; Bennett T E; Steelman L S; McCubrey J A
Differential effect of phorbol esters and interleukin-3 on protein kinase C isoform content and kinase activity in the FDC-P1 cell line.
Blood 1991;78(10):2633-41.
1991: McCubrey J A; Steelman L S; Mayo M W; Algate P A; Dellow R A; Kaleko M
Growth-promoting effects of insulin-like growth factor-1 (IGF-1) on hematopoietic cells: overexpression of introduced IGF-1 receptor abrogates interleukin-3 dependency of murine factor-dependent cells by a ligand-dependent mechanism.
Blood 1991;78(4):921-9.
1991: McCubrey J A; Steelman L S; McKearn J P
Interleukin-3 and phorbol esters induce different patterns of immediate-early gene expression in an interleukin-3 dependent cell line.
Oncogene research 1991;6(1):1-12.
1990: McCubrey J A; Steelman L S; Sandlin G; Riddle R S; Ways D K
Effects of phorbol esters on an interleukin-3-dependent cell line.
Blood 1990;76(1):63-72.
1989: McCubrey J A; Steelman L S; Risser R G; McKearn J P
Structure and expression of the T cell receptor gamma locus in pre-B and early hemopoietic cells.
European journal of immunology 1989;19(12):2303-8.
1989: Buttke T M; Van Cleave S; Steelman L; McCubrey J A
Absence of unsaturated fatty acid synthesis in murine T lymphocytes.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(16):6133-7.
1989: McCubrey J; Holland G; McKearn J; Risser R
Abrogation of factor-dependence in two IL-3-dependent cell lines can occur by two distinct mechanisms.
Oncogene research 1989;4(2):97-109.
1986: Green P L; Holland G D; Kaehler D; McKearn J; McCubrey J; Risser R
Determinants of Abelson murine leukemia virus pathogenesis.
Current topics in microbiology and immunology 1986;132():62-74.
1985: McKearn J P; McCubrey J; Fagg B
Enrichment of hematopoietic precursor cells and cloning of multipotential B-lymphocyte precursors.
Proceedings of the National Academy of Sciences of the United States of America 1985;82(21):7414-8.
1985: McCubrey J; McKearn J P; Köhler G
Transformation of B and non-B cell lines with the 2,4,6,-trinitrophenyl (TNP)-specific immunoglobulin genes.
European journal of immunology 1985;15(11):1117-24.
1983: McCubrey J; Risser R
Activation of nonexpressed endogenous ecotropic murine leukemia virus by transfection of genomic DNA into embryo cells.
Journal of virology 1983;45(3):950-5.
1983: Risser R; Horowitz J M; McCubrey J
Endogenous mouse leukemia viruses.
Annual review of genetics 1983;17():85-121.
1982: McCubrey J; Horowitz J M; Risser R
Structure and expression of endogenous ecotropic murine leukemia viruses in RF/J mice.
The Journal of experimental medicine 1982;156(5):1461-74.
1982: McCubrey J; Risser R
Genetic interactions in the spontaneous production of endogenous murine leukemia virus in low leukemic mouse strains.
The Journal of experimental medicine 1982;156(2):337-49.
1982: McCubrey J; Risser R
Genetic interactions in induction of endogenous murine leukemia virus from low leukemic mice.
Cell 1982;28(4):881-8.
1982: McCubrey J; Risser R
Allelism and linkage studies of murine leukemia virus activation genes in low leukemic strains of mice.
The Journal of experimental medicine 1982;155(4):1233-8.

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