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Valarie McCullar

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Graft vs Host Disease

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Michelle K Gleason; Valarie McCullar; Angela Panoskaltsis-Mortari; Deborah A Todhunter; Daniel A Vallera; Michael verneris; Louis M Weiner; Bin Zhang; Sophia X Zhou; Jeffrey S Miller
Bispecific and trispecific killer cell engagers directly activate human NK cells through CD16 signaling and induce cytotoxicity and cytokine production.
Michelle K Gleason; Mitsuomi Hirashima; Carol J Holman; Todd R Lenvik; Valarie McCullar; Bruce R Blazar; Frank Cichocki; Sarah Cooley; Martin Felices; Toshiro Niki; M Shea O'Brien; Angela Panoskaltsis-Mortari; Michael verneris; Jeffrey S Miller
Tim-3 is an inducible human natural killer cell receptor that enhances interferon gamma production in response to galectin-9.
Frank Cichocki; Rebecca J Hanson; Todd Lenvik; Michelle Pitt; Valarie McCullar; Hongchuan Li; Stephen K Anderson; Jeffrey S Miller
The transcription factor c-Myc enhances KIR gene transcription through direct binding to an upstream distal promoter element.

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2012: Michelle K Gleason; Valarie McCullar; Angela Panoskaltsis-Mortari; Deborah A Todhunter; Daniel A Vallera; Michael verneris; Louis M Weiner; Bin Zhang; Sophia X Zhou; Jeffrey S Miller
Bispecific and trispecific killer cell engagers directly activate human NK cells through CD16 signaling and induce cytotoxicity and cytokine production.
Molecular cancer therapeutics 2012;11(12):2674-84.
2012: Michelle K Gleason; Mitsuomi Hirashima; Carol J Holman; Todd R Lenvik; Valarie McCullar; Bruce R Blazar; Frank Cichocki; Sarah Cooley; Martin Felices; Toshiro Niki; M Shea O'Brien; Angela Panoskaltsis-Mortari; Michael verneris; Jeffrey S Miller
Tim-3 is an inducible human natural killer cell receptor that enhances interferon gamma production in response to galectin-9.
Blood 2012;119(13):3064-72.
2009: Frank Cichocki; Rebecca J Hanson; Todd Lenvik; Michelle Pitt; Valarie McCullar; Hongchuan Li; Stephen K Anderson; Jeffrey S Miller
The transcription factor c-Myc enhances KIR gene transcription through direct binding to an upstream distal promoter element.
Blood 2009;113(14):3245-53.
2009: Veronika Bachanova; Valarie McCullar; Todd Lenvik; Rosanna Wangen; Karen A Peterson; Dave E M Ankarlo; Angela Panoskaltsis-Mortari; John E Wagner; Jeffrey S Miller
Activated notch supports development of cytokine producing NK cells which are hyporesponsive and fail to acquire NK cell effector functions.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2009;15(2):183-94.
2008: Valarie McCullar; Robert Oostendorp; Angela Panoskaltsis-Mortari; Gong Yun; Charles T Lutz; John E Wagner; Jeffrey S Miller
Mouse fetal and embryonic liver cells differentiate human umbilical cord blood progenitors into CD56-negative natural killer cell precursors in the absence of interleukin-15.
Experimental hematology 2008;36(5):598-608.
2007: Hongbo Wang; Bartosz Grzywacz; David J Sukovich; Valarie McCullar; Qing Cao; Alisa B Lee; Bruce R Blazar; David N Cornfield; Jeffrey S Miller; Michael verneris
The unexpected effect of cyclosporin A on CD56+CD16- and CD56+CD16+ natural killer cell subpopulations.
Blood 2007;110(5):1530-9.
2007: Sarah Cooley; Feng Xiao; Michelle Pitt; Michelle Gleason; Valarie McCullar; Tracy L Bergemann; Karina L McQueen; Lisbeth A Guethlein; Peter Parham; Jeffrey S Miller
A subpopulation of human peripheral blood NK cells that lacks inhibitory receptors for self-MHC is developmentally immature.
Blood 2007;110(2):578-86.
2007: Troy Lund; Lorraine B Anderson; Valarie McCullar; LeeAnn Higgins; Gong H Yun; Bartosz Grzywacz; Michael verneris; Jeffrey S Miller
iTRAQ is a useful method to screen for membrane-bound proteins differentially expressed in human natural killer cell types.
Journal of proteome research 2007;6(2):644-53.
2005: Sarah Cooley; Valarie McCullar; Rosanna Wangen; Tracy L Bergemann; Stephen Spellman; Daniel J Weisdorf; Jeffrey S Miller
KIR reconstitution is altered by T cells in the graft and correlates with clinical outcomes after unrelated donor transplantation.
Blood 2005;106(13):4370-6.