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James McCulloch

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Abigail G Herrmann; Lorraine E Kerr; Thierry Le Bihan; Mailis C McCulloch; James L Searcy; Ruth F Deighton; James McCulloch
Adaptive changes in the neuronal proteome: mitochondrial energy production, endoplasmic reticulum stress, and ribosomal dysfunction in the cellular response to metabolic stress.
Philip R Holland; Mark E Bastin; Robin B Coltman; Ian J Deary; Maurits A Jansen; Karim Khallout; Ian Marshall; James McCulloch; Gavin D Merrifield; Hanna Nowers; Fiona Scott; Joanna M Wardlaw; Karen Horsburgh
MRI is a sensitive marker of subtle white matter pathology in hypoperfused mice.
Robin Coltman; Stephanie Daumas; Ian J Deary; Jill H Fowler; Mike Allerhand; Masafumi Ihara; Rajesh N. Kalaria; James McCulloch; Fiona Scott; Gillian Scullion; Jessica Smith; Aisling Spain; Yanina Tsenkina; Emma Wood; Karen Horsburgh
Selective white matter pathology induces a specific impairment in spatial working memory.

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2013: Abigail G Herrmann; Lorraine E Kerr; Thierry Le Bihan; Mailis C McCulloch; James L Searcy; Ruth F Deighton; James McCulloch
Adaptive changes in the neuronal proteome: mitochondrial energy production, endoplasmic reticulum stress, and ribosomal dysfunction in the cellular response to metabolic stress.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2013;33(5):673-83.
2011: Philip R Holland; Mark E Bastin; Robin B Coltman; Ian J Deary; Maurits A Jansen; Karim Khallout; Ian Marshall; James McCulloch; Gavin D Merrifield; Hanna Nowers; Fiona Scott; Joanna M Wardlaw; Karen Horsburgh
MRI is a sensitive marker of subtle white matter pathology in hypoperfused mice.
Neurobiology of aging 2011;32(12):2325.e1-6.
2011: Robin Coltman; Stephanie Daumas; Ian J Deary; Jill H Fowler; Mike Allerhand; Masafumi Ihara; Rajesh N. Kalaria; James McCulloch; Fiona Scott; Gillian Scullion; Jessica Smith; Aisling Spain; Yanina Tsenkina; Emma Wood; Karen Horsburgh
Selective white matter pathology induces a specific impairment in spatial working memory.
Neurobiology of aging 2011;32(12):2324.e7-12.
2009: Ruth F Deighton; Duncan M Short; Richard J McGregor; Alan J Gow; Ian R Whittle; James McCulloch
The utility of functional interaction and cluster analysis in CNS proteomics.
Journal of neuroscience methods 2009;180(2):321-9.
2008: Jane Thompson; Keith Finlayson; Eliane Salvo-Chirnside; David MacDonald; James McCulloch; Lorraine E Kerr; John Sharkey
Characterisation of the Bax-nucleophosmin interaction: the importance of the Bax C-terminus.
Apoptosis : an international journal on programmed cell death 2008;13(3):394-403.
2007: Manuela De Michele; Giuliano Sette; D T Chalmers; D Dewar; Danilo Toni; Giuseppe Sancesario; James McCulloch
Focal cerebral ischaemia induces corticotropin releasing factor (CRF) vascular immunoreactivity in rat occluded hemisphere.
Regulatory peptides 2007;143(1-3):69-75.
2007: Duncan M Short; Ian D Heron; Jui-Lee A Birse-Archbold; Lorraine E Kerr; John Sharkey; James McCulloch
Apoptosis induced by staurosporine alters chaperone and endoplasmic reticulum proteins: Identification by quantitative proteomics.
Proteomics 2007;7(17):3085-96.
2007: Lorraine E Kerr; Jui-Lee A Birse-Archbold; Duncan M Short; Ailsa L McGregor; I Heron; D C Macdonald; J Thompson; G J Carlson; John S Kelly; James McCulloch; John Sharkey
Nucleophosmin is a novel Bax chaperone that regulates apoptotic cell death.
Oncogene 2007;26(18):2554-62.
2007: Sandra Magnoni; A Baker; S Thomson; G Jordan; Sarah George; Barry W McColl; James McCulloch; Karen Horsburgh
Neuroprotective effect of adenoviral-mediated gene transfer of TIMP-1 and -2 in ischemic brain injury.
Gene therapy 2007;14(7):621-5.
2007: Oliver P Voss; Stuart Milne; John Sharkey; Michael J O'Neill; James McCulloch
Molecular mechanisms of neurite growth with AMPA receptor potentiation.
Neuropharmacology 2007;52(2):590-7.
2006: Louise Dickson; Ichiro Aramori; James McCulloch; John Sharkey; Keith Finlayson
A systematic comparison of intracellular cyclic AMP and calcium signalling highlights complexities in human VPAC/PAC receptor pharmacology.
Neuropharmacology 2006;51(6):1086-98.
2006: Daniel J Cuthill; Jill H Fowler; James McCulloch; Deborah Dewar
Different patterns of axonal damage after intracerebral injection of malonate or AMPA.
Experimental neurology 2006;200(2):509-20.
2006: Jill H Fowler; Julia M Edgar; A Pringle; Mark McLaughlin; James McCulloch; Ian R Griffiths; James Y Garbern; Klaus-Armin Nave; Deborah Dewar
Alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid-mediated excitotoxic axonal damage is attenuated in the absence of myelin proteolipid protein.
Journal of neuroscience research 2006;84(1):68-77.
2005: Jui-Lee A Birse-Archbold; Lorraine E Kerr; Paul Jones; James McCulloch; John Sharkey
Differential profile of Nix upregulation and translocation during hypoxia/ischaemia in vivo versus in vitro.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2005;25(10):1356-65.
2005: Manuela De Michele; Omar Touzani; Alan C Foster; Cesare Fieschi; Giuliano Sette; James McCulloch
Corticotropin-releasing factor: effect on cerebral blood flow in physiologic and ischaemic conditions.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 2005;165(3):375-82.
2005: Graeme R Jordan; James McCulloch; Mohammed Shahid; David R Hill; Brian Henry; Karen Horsburgh
Regionally selective and dose-dependent effects of the ampakines Org 26576 and Org 24448 on local cerebral glucose utilisation in the mouse as assessed by 14C-2-deoxyglucose autoradiography.
Neuropharmacology 2005;49(2):254-64.
2005: Stuart A Milne; Ailsa L McGregor; James McCulloch; John Sharkey
Increased expression of macrophage receptor with collagenous structure (MARCO) in mouse cortex following middle cerebral artery occlusion.
Neuroscience letters 2005;383(1-2):58-62.
2004: Sandra Magnoni; Andrew Baker; Sarah George; W Colin Duncan; Lorraine E Kerr; James McCulloch; Karen Horsburgh
Differential alterations in the expression and activity of matrix metalloproteinases 2 and 9 after transient cerebral ischemia in mice.
Neurobiology of disease 2004;17(2):188-97.
2004: Jill H Fowler; Katherine Whalley; Tracey Murray; Michael J O'Neill; James McCulloch
The AMPA receptor potentiator LY404187 increases cerebral glucose utilization and c-fos expression in the rat.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2004;24(10):1098-109.
2004: Keith Finlayson; Harry J Witchel; James McCulloch; John Sharkey
Acquired QT interval prolongation and HERG: implications for drug discovery and development.
European journal of pharmacology 2004;500(1-3):129-42.
2004: Barry W McColl; Hilary V O Carswell; James McCulloch; Karen Horsburgh
Extension of cerebral hypoperfusion and ischaemic pathology beyond MCA territory after intraluminal filament occlusion in C57Bl/6J mice.
Brain research 2004;997(1):15-23.
2003: Jill H Fowler; Eileen McCracken; Deborah Dewar; James McCulloch
Intracerebral injection of AMPA causes axonal damage in vivo.
Brain research 2003;991(1-2):104-12.
2003: Eileen McCracken; Deborah Dewar; James McCulloch
Sipatrigine and oligodendrocyte and axonal pathology following transient focal cerebral ischaemia in the rat.
Neuroreport 2003;14(3):517-20.
2002: Eileen McCracken; Jill H Fowler; Deborah Dewar; Steve Morrison; James McCulloch
Grey matter and white matter ischemic damage is reduced by the competitive AMPA receptor antagonist, SPD 502.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2002;22(9):1090-7.
2002: Hideaki Imai; James McCulloch; David I Graham; Hiroyuki Masayasu; I Mhairi Macrae
New method for the quantitative assessment of axonal damage in focal cerebral ischemia.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2002;22(9):1080-9.
2002: Hideaki Imai; June Harland; James McCulloch; David I Graham; S Moira Brown; I Mhairi Macrae
Specific expression of the cell cycle regulation proteins, GADD34 and PCNA, in the peri-infarct zone after focal cerebral ischaemia in the rat.
The European journal of neuroscience 2002;15(12):1929-36.
2002: Stephen Kelly; Alison Bieneman; James B Uney; James McCulloch
Cerebral glucose utilization in transgenic mice overexpressing heat shock protein 70 is altered by dizocilpine.
The European journal of neuroscience 2002;15(6):945-52.
2001: S Kelly; James McCulloch; Karen Horsburgh
Minimal ischaemic neuronal damage and HSP70 expression in MF1 strain mice following bilateral common carotid artery occlusion.
Brain research 2001;914(1-2):185-95.
2001: S Kelly; Alison Bieneman; Karen Horsburgh; D Hughes; M V Sofroniew; James McCulloch; James B Uney
Targeting expression of hsp70i to discrete neuronal populations using the Lmo-1 promoter: assessment of the neuroprotective effects of hsp70i in vivo and in vitro.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2001;21(8):972-81.
2000: Karen Horsburgh; James McCulloch; Margaret Nilsen; Allen D Roses; Nicoll James
Increased neuronal damage and apoE immunoreactivity in human apolipoprotein E, E4 isoform-specific, transgenic mice after global cerebral ischaemia.
The European journal of neuroscience 2000;12(12):4309-17.
2000: Eileen McCracken; V Valeriani; C Simpson; T Jover; James McCulloch; Deborah Dewar
The lipid peroxidation by-product 4-hydroxynonenal is toxic to axons and oligodendrocytes.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2000;20(11):1529-36.
2000: J Owens; A A Tebbutt; Ailsa L McGregor; K Kodama; SS Magar; ME Perlman; D J Robins; GJ Durant; James McCulloch
Synthesis and binding characteristics of N-(1-naphthyl)-N'-(3-[(125)I]-iodophenyl)-N'-methylguanidine ([(125)I]-CNS 1261): a potential SPECT agent for imaging NMDA receptor activation.
Nuclear medicine and biology 2000;27(6):557-64.
2000: Hilary V O Carswell; Niall H Anderson; James J Morton; James McCulloch; Anna F Dominiczak; I Mhairi Macrae
Investigation of estrogen status and increased stroke sensitivity on cerebral blood flow after a focal ischemic insult.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2000;20(6):931-6.
2000: Philippa S Yam; Laurence T Dunn; David I Graham; Deborah Dewar; James McCulloch
NMDA receptor blockade fails to alter axonal injury in focal cerebral ischemia.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2000;20(5):772-9.
2000: V Valeriani; Deborah Dewar; James McCulloch
Quantitative assessment of ischemic pathology in axons, oligodendrocytes, and neurons: attenuation of damage after transient ischemia.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2000;20(5):765-71.
2000: Karen Horsburgh; James McCulloch; Margaret Nilsen; Eileen McCracken; CH Large; Allen D Roses; Nicoll James
Intraventricular infusion of apolipoprotein E ameliorates acute neuronal damage after global cerebral ischemia in mice.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2000;20(3):458-62.
2000: Duncan MacGregor; Hilary V O Carswell; David I Graham; James McCulloch; I Mhairi Macrae
Impaired cerebral autoregulation 24 h after induction of transient unilateral focal ischaemia in the rat.
The European journal of neuroscience 2000;12(1):58-66.
1999: AG Lam; James A Monn; D D Schoepp; D Lodge; James McCulloch
Group II selective metabotropic glutamate receptor agonists and local cerebral glucose use in the rat.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1999;19(10):1083-91.
1999: Gernot Riedel; Jacques Micheau; AG Lam; E L Roloff; Stephen J Martin; H Bridge; Livia de Hoz; B Poeschel; James McCulloch; Richard G M Morris
Reversible neural inactivation reveals hippocampal participation in several memory processes.
Nature neuroscience 1999;2(10):898-905.
1999: Deborah Dewar; Philippa S Yam; James McCulloch
Drug development for stroke: importance of protecting cerebral white matter.
European journal of pharmacology 1999;375(1-3):41-50.
1999: Karen Horsburgh; S Kelly; James McCulloch; G A Higgins; Allen D Roses; Nicoll James
Increased neuronal damage in apolipoprotein E-deficient mice following global ischaemia.
Neuroreport 1999;10(4):837-41.
1998: AG Lam; M A Soriano; James A Monn; D D Schoepp; D Lodge; James McCulloch
Effects of the selective metabotropic glutamate agonist LY354740 in a rat model of permanent ischaemia.
Neuroscience letters 1998;254(2):121-3.
1998: AG Lam; JM Campbell; NK Bennett; AP Payne; Roger Wayne Davies; RG Sutcliffe; James McCulloch
Local cerebral glucose utilization in the AS/AGU rat: a mutant with movement disorders.
The European journal of neuroscience 1998;10(6):1963-7.
1998: Philippa S Yam; J Patterson; David I Graham; T Takasago; Deborah Dewar; James McCulloch
Topographical and quantitative assessment of white matter injury following a focal ischaemic lesion in the rat brain.
Brain research. Brain research protocols 1998;2(4):315-22.
1998: Philippa S Yam; Deborah Dewar; James McCulloch
Axonal injury caused by focal cerebral ischemia in the rat.
Journal of neurotrauma 1998;15(6):441-50.
1998: S E Browne; J L Muir; Trevor W Robbins; K J Page; Barry J Everitt; James McCulloch
The cerebral metabolic effects of manipulating glutamatergic systems within the basal forebrain in conscious rats.
The European journal of neuroscience 1998;10(2):649-63.
1997: Omar Touzani; S Galbraith; P Siegl; James McCulloch
Endothelin-B receptors in cerebral resistance arterioles and their functional significance after focal cerebral ischemia in cats.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1997;17(11):1157-65.
1997: Philippa S Yam; T Takasago; Deborah Dewar; David I Graham; James McCulloch
Amyloid precursor protein accumulates in white matter at the margin of a focal ischaemic lesion.
Brain research 1997;760(1-2):150-7.
1997: E A Irving; K Yatsushiro; James McCulloch; Deborah Dewar
Rapid alteration of tau in oligodendrocytes after focal ischemic injury in the rat: involvement of free radicals.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1997;17(6):612-22.
1997: E A Irving; James McCulloch; Deborah Dewar
The effect of postmortem delay on the distribution of microtubule-associated proteins tau, MAP2, and MAP5 in the rat.
Molecular and chemical neuropathology / sponsored by the International Society for Neurochemistry and the World Federation of Neurology and research groups on neurochemistry and cerebrospinal fluid 1997;30(3):253-71.
1997: Karen Horsburgh; K B Mackay; James McCulloch
Intracortical glutamate perfusion in vivo induces cellular alterations in specific protein kinase C isoforms and amyloid precursor protein.
Experimental neurology 1997;143(2):207-18.
1996: James McCulloch
Neuroprotective drug development in stroke: blood pressure and its impact.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 1996;14(5):S131-8.
1996: T R Patel; S Galbraith; D I Graham; Hazem Hallak; AM Doherty; James McCulloch
Endothelin receptor antagonist increases cerebral perfusion and reduces ischaemic damage in feline focal cerebral ischaemia.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1996;16(5):950-8.
1996: E A Irving; James McCulloch; Deborah Dewar
Intracortical perfusion of glutamate in vivo induces alterations of tau and microtubule-associated protein 2 immunoreactivity in the rat.
Acta neuropathologica 1996;92(2):186-96.
1996: T R Patel; S Galbraith; M A McAuley; James McCulloch
Endothelin-mediated vascular tone following focal cerebral ischaemia in the cat.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1996;16(4):679-87.
1996: M A McAuley; V Breu; D I Graham; James McCulloch
The effects of bosentan on cerebral blood flow and histopathology following middle cerebral artery occlusion in the rat.
European journal of pharmacology 1996;307(2):171-81.
1996: T R Patel; M A McAuley; James McCulloch
Endothelin receptor mediated constriction and dilatation in feline cerebral resistance arterioles in vivo.
European journal of pharmacology 1996;307(1):41-8.
1996: T R Patel; James McCulloch
Failure of an endothelin antagonist to modify hypoperfusion after transient global ischaemia in the rat.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1996;16(3):490-9.
1996: K B MacKay; T R Patel; S L Galbraith; G N Woodruff; James McCulloch
The relationship between glutamate release and cerebral blood flow after focal cerebral ischaemia in the cat: effect of pretreatment with enadoline (a kappa receptor agonist).
Brain research 1996;712(2):329-34.
1995: T R Patel; James McCulloch
AMPA receptor antagonism attenuates MK-801-induced hypermetabolism in the posterior cingulate cortex.
Brain research 1995;686(2):254-8.
1995: M Ikeda; Deborah Dewar; James McCulloch
Galanin receptor binding sites in the temporal and occipital cortex are minimally affected in Alzheimer's disease.
Neuroscience letters 1995;192(1):37-40.
1995: T R Patel; James McCulloch
Postischemic hypoperfusion in transient global ischemia: a role for endothelins?
Journal of cardiovascular pharmacology 1995;26 Suppl 3():S425-8.
1995: T R Patel; S L Galbraith; M A McAuley; AM Doherty; D I Graham; James McCulloch
Therapeutic potential of endothelin receptor antagonists in experimental stroke.
Journal of cardiovascular pharmacology 1995;26 Suppl 3():S412-5.
1994: P E Bannan; D I Graham; Kennedy R Lees; James McCulloch
Neuroprotective effect of remacemide hydrochloride in focal cerebral ischemia in the cat.
Brain research 1994;664(1-2):271-5.
1994: D A Dawson; D I Graham; James McCulloch; I Mhairi Macrae
Anti-ischaemic efficacy of a nitric oxide synthase inhibitor and a N-methyl-D-aspartate receptor antagonist in models of transient and permanent focal cerebral ischaemia.
British journal of pharmacology 1994;113(1):247-53.
1994: T R Patel; M A McAuley; James McCulloch
Effects on feline pial arterioles in situ of bosentan, a non-peptide endothelin receptor antagonist.
European journal of pharmacology 1994;260(1):65-71.
1994: Ross Bullock; D I Graham; S Swanson; James McCulloch
Neuroprotective effect of the AMPA receptor antagonist LY-293558 in focal cerebral ischemia in the cat.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1994;14(3):466-71.
1994: K B Mackay; James McCulloch
Distribution of effects of the kappa-opioid agonist CI-977 on cerebral glucose utilization in rat brain.
Brain research 1994;642(1-2):160-8.
1994: S E Browne; James McCulloch
AMPA receptor antagonists and local cerebral glucose utilization in the rat.
Brain research 1994;641(1):10-20.
1994: K B Mackay; Deborah Dewar; James McCulloch
kappa-1 Opioid receptors of the temporal cortex are preserved in Alzheimer's disease.
Journal of neural transmission. Parkinson's disease and dementia section 1994;7(1):73-9.
1994: P Mathew; D I Graham; Ross Bullock; W Maxwell; James McCulloch; G Teasdale
Focal brain injury: histological evidence of delayed inflammatory response in a new rodent model of focal cortical injury.
Acta neurochirurgica. Supplementum 1994;60():428-30.
1993: M Ikeda; Deborah Dewar; James McCulloch
Differential alterations of ion channel binding sites in temporal and occipital regions of the cerebral cortex in Alzheimer's disease.
Brain research 1993;630(1-2):50-6.
1993: Brian M Ross; D Dawson; Deborah Dewar; M Macrae; J Knowler; James McCulloch
Effects of post-mortem delay on high affinity forskolin binding sites and adenylate cyclase activity in rat and human striatum and cerebral cortex.
Brain research 1993;629(2):225-30.
1993: K B Mackay; K Kusumoto; D I Graham; James McCulloch
Effect of the kappa-1 opioid agonist CI-977 on ischemic brain damage and cerebral blood flow after middle cerebral artery occlusion in the rat.
Brain research 1993;629(1):10-8.
1993: H Fujisawa; D Dawson; S E Browne; K B MacKay; Ross Bullock; James McCulloch
Pharmacological modification of glutamate neurotoxicity in vivo.
Brain research 1993;629(1):73-8.
1993: I M Macrae; D A Dawson; J D Norrie; James McCulloch
Inhibition of nitric oxide synthesis: effects on cerebral blood flow and glucose utilisation in the rat.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1993;13(6):985-92.
1993: Brian M Ross; M McLaughlin; M Roberts; Graeme Milligan; James McCulloch; J T Knowler
Alterations in the activity of adenylate cyclase and high affinity GTPase in Alzheimer's disease.
Brain research 1993;622(1-2):35-42.
1993: K B Mackay; K Kusumoto; D I Graham; James McCulloch
Focal cerebral ischemia in the cat: pretreatment with a kappa-1 opioid receptor agonist, CI-977.
Brain research 1993;618(2):213-9.
1993: M Ikeda; K B Mackay; Deborah Dewar; James McCulloch
Differential alterations in adenosine A1 and kappa 1 opioid receptors in the striatum in Alzheimer's disease.
Brain research 1993;616(1-2):211-7.
1993: Karen Horsburgh; F M Inglis; James McCulloch
Focal increases in [3H]forskolin and [3H]phorbol 12,13-dibutyrate binding in the rat brain following lesions of the medial septum.
Neuroscience letters 1993;151(2):166-9.
1993: I M Macrae; M J Robinson; D I Graham; J L Reid; James McCulloch
Endothelin-1-induced reductions in cerebral blood flow: dose dependency, time course, and neuropathological consequences.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1993;13(2):276-84.
1993: James McCulloch; E Ozyurt; C K Park; D G Nehls; Graham M Teasdale; D I Graham
Glutamate receptor antagonists in experimental focal cerebral ischaemia.
Acta neurochirurgica. Supplementum 1993;57():73-9.
1993: M Ikeda; Deborah Dewar; James McCulloch
High affinity hippocampal [3H]-glibenclamide binding sites are preserved in Alzheimer's disease.
Journal of neural transmission. Parkinson's disease and dementia section 1993;5(3):177-84.
1993: Deborah Dewar; D I Graham; Graham M Teasdale; James McCulloch
Alz-50 and ubiquitin immunoreactivity is induced by permanent focal cerebral ischaemia in the cat.
Acta neuropathologica 1993;86(6):623-9.
1992: M Ikeda; Deborah Dewar; James McCulloch
A correlative study of calcium channel antagonist binding and local neuropathological features in the hippocampus in Alzheimer's disease.
Brain research 1992;589(2):313-9.
1992: Brian M Ross; J T Knowler; James McCulloch
On the stability of messenger RNA and ribosomal RNA in the brains of control human subjects and patients with Alzheimer's disease.
Journal of neurochemistry 1992;58(5):1810-9.
1992: K Kusumoto; K B Mackay; James McCulloch
The effect of the kappa-opioid receptor agonist CI-977 in a rat model of focal cerebral ischaemia.
Brain research 1992;576(1):147-51.
1992: M C Wallace; Graham M Teasdale; James McCulloch
Autoradiographic analysis of 3H-MK-801 (dizocilpine) in vivo uptake and in vitro binding after focal cerebral ischemia in the rat.
Journal of neurosurgery 1992;76(1):127-33.
1992: Ross Bullock; Y Kuroda; Graham M Teasdale; James McCulloch
Prevention of post-traumatic excitotoxic brain damage with NMDA antagonist drugs: a new strategy for the nineties.
Acta neurochirurgica. Supplementum 1992;55():49-55.
1991: M Ikeda; Deborah Dewar; James McCulloch
Preservation of [125I]galanin binding sites despite loss of cholinergic neurones to the hippocampus in Alzheimer's disease.
Brain research 1991;568(1-2):303-6.
1991: M Ikeda; Deborah Dewar; James McCulloch
Selective reduction of [125I]apamin binding sites in Alzheimer hippocampus: a quantitative autoradiographic study.
Brain research 1991;567(1):51-6.
1991: A Kurumaji; M Ikeda; Deborah Dewar; A G McCormack; James McCulloch
Effects of chronic administration of MK-801 upon local cerebral glucose utilisation and ligand binding to the NMDA receptor complex.
Brain research 1991;563(1-2):57-65.
1991: Karen Horsburgh; James McCulloch
Differential alterations of second messenger systems and cerebral glucose use following excitotoxic lesion of rat cerebral cortex.
Brain research 1991;563(1-2):306-10.
1991: James McCulloch; L L Iversen
Autoradiographic assessment of the effects of N-methyl-D-aspartate (NMDA) receptor antagonists in vivo.
Neurochemical research 1991;16(9):951-63.
1991: Deborah Dewar; D T Chalmers; D I Graham; James McCulloch
Glutamate metabotropic and AMPA binding sites are reduced in Alzheimer's disease: an autoradiographic study of the hippocampus.
Brain research 1991;553(1):58-64.
1991: M McLaughlin; Brian M Ross; Graeme Milligan; James McCulloch; J T Knowler
Robustness of G proteins in Alzheimer's disease: an immunoblot study.
Journal of neurochemistry 1991;57(1):9-14.
1991: M Chen; Ross Bullock; D I Graham; P Frey; D Lowe; James McCulloch
Evaluation of a competitive NMDA antagonist (D-CPPene) in feline focal cerebral ischemia.
Annals of neurology 1991;30(1):62-70.
1991: M H Chen; Ross Bullock; D I Graham; J D Miller; James McCulloch
Ischemic neuronal damage after acute subdural hematoma in the rat: effects of pretreatment with a glutamate antagonist.
Journal of neurosurgery 1991;74(6):944-50.
1991: Karen Horsburgh; James McCulloch
Alterations of functional glucose use and ligand binding to second messenger systems following unilateral orbital enucleation.
Brain research 1991;549(2):317-21.
1991: Ross Bullock; Steven P Butcher; M H Chen; L Kendall; James McCulloch
Correlation of the extracellular glutamate concentration with extent of blood flow reduction after subdural hematoma in the rat.
Journal of neurosurgery 1991;74(5):794-802.
1991: Karen Horsburgh; Deborah Dewar; D I Graham; James McCulloch
Autoradiographic imaging of [3H]phorbol 12,13-dibutyrate binding to protein kinase C in Alzheimer's disease.
Journal of neurochemistry 1991;56(4):1121-9.
1991: James McCulloch
Ischaemic brain damage--prevention with competitive and non-competitive antagonists of N-methyl-D-aspartate receptors.
Arzneimittel-Forschung 1991;41(3A):319-24.
1991: D T Chalmers; James McCulloch
Alterations in neurotransmitter receptors and glucose use after unilateral orbital enucleation.
Brain research 1991;540(1-2):243-54.
1991: I Mhairi Macrae; M A McAuley; M J Robinson; John L Reid; James McCulloch
Endothelin-1-induced hypertension: a consequence of medullary ischemia?
Journal of cardiovascular pharmacology 1991;17 Suppl 7():S496-9.
1991: M J Robinson; I Mhairi Macrae; M Todd; John L Reid; James McCulloch
Reduction in local cerebral blood flow induced by endothelin-1 applied topically to the middle cerebral artery in the rat.
Journal of cardiovascular pharmacology 1991;17 Suppl 7():S354-7.
1990: Deborah Dewar; D T Chalmers; A Shand; D I Graham; James McCulloch
Selective reduction of quisqualate (AMPA) receptors in Alzheimer cerebellum.
Annals of neurology 1990;28(6):805-10.
1990: Karen Horsburgh; I Jansen; L Edvinsson; James McCulloch
Second messenger systems: functional role in cerebrovascular smooth muscle regulation.
European journal of pharmacology 1990;191(2):205-11.
1990: Ross Bullock; James McCulloch; D I Graham; D Lowe; M H Chen; Graham M Teasdale
Focal ischemic damage is reduced by CPP-ene studies in two animal models.
Stroke; a journal of cerebral circulation 1990;21(11 Suppl):III32-6.
1990: A Kurumaji; James McCulloch
Effects of MK-801 upon local cerebral glucose utilisation in conscious rats following unilateral lesion of caudal entorhinal cortex.
Brain research 1990;531(1-2):72-82.
1990: M J Robinson; I Mhairi Macrae; M Todd; John L Reid; James McCulloch
Reduction of local cerebral blood flow to pathological levels by endothelin-1 applied to the middle cerebral artery in the rat.
Neuroscience letters 1990;118(2):269-72.
1990: Ross Bullock; D I Graham; M H Chen; D Lowe; James McCulloch
Focal cerebral ischemia in the cat: pretreatment with a competitive NMDA receptor antagonist, D-CPP-ene.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1990;10(5):668-74.
1990: A Kurumaji; James McCulloch
Effects of unilateral intrahippocampal injection of MK-801 upon local cerebral glucose utilisation in conscious rats.
Brain research 1990;518(1-2):342-6.
1990: I Mhairi Macrae; D Dewar; John L Reid; James McCulloch
Specific alterations in cardiovascular function and in glucose utilisation within lower brainstem nuclei following intracisternal neuropeptide Y in the conscious rat.
Brain research 1990;515(1-2):99-103.
1990: D G Nehls; C K Park; A G MacCormack; James McCulloch
The effects of N-methyl-D-aspartate receptor blockade with MK-801 upon the relationship between cerebral blood flow and glucose utilisation.
Brain research 1990;511(2):271-9.
1990: Deborah Dewar; Karen Horsburgh; D I Graham; D N Brooks; James McCulloch
Selective alterations of high affinity [3H]forskolin binding sites in Alzheimer's disease: a quantitative autoradiographic study.
Brain research 1990;511(2):241-8.
1990: M J Robinson; James McCulloch
Contractile responses to endothelin in feline cortical vessels in situ.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1990;10(2):285-9.
1990: D T Chalmers; Deborah Dewar; D I Graham; D N Brooks; James McCulloch
Differential alterations of cortical glutamatergic binding sites in senile dementia of the Alzheimer type.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(4):1352-6.
1990: Deborah Dewar; D I Graham; James McCulloch
5 HT2 receptors in dementia of Alzheimer type: a quantitative autoradiographic study of frontal cortex and hippocampus.
Journal of neural transmission. Parkinson's disease and dementia section 1990;2(2):129-37.
1989: C K Park; D G Nehls; Graham M Teasdale; James McCulloch
Effect of the NMDA antagonist MK-801 on local cerebral blood flow in focal cerebral ischaemia in the rat.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1989;9(5):617-22.
1989: Deborah Dewar; M C Wallace; A Kurumaji; James McCulloch
Alterations in the N-methyl-D-aspartate receptor complex following focal cerebral ischemia.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1989;9(5):709-12.
1989: A Kurumaji; D G Nehls; C K Park; James McCulloch
Effects of NMDA antagonists, MK-801 and CPP, upon local cerebral glucose use.
Brain research 1989;496(1-2):268-84.
1989: D T Chalmers; James McCulloch
Reduction in [3H]glutamate binding in the visual cortex after unilateral orbital enucleation.
Neuroscience letters 1989;97(3):298-304.
1988: C K Park; D G Nehls; D I Graham; Graham M Teasdale; James McCulloch
Focal cerebral ischaemia in the cat: treatment with the glutamate antagonist MK-801 after induction of ischaemia.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1988;8(5):757-62.
1988: C K Park; D G Nehls; D I Graham; Graham M Teasdale; James McCulloch
The glutamate antagonist MK-801 reduces focal ischemic brain damage in the rat.
Annals of neurology 1988;24(4):543-51.
1988: D G Nehls; A Kurumaji; C K Park; James McCulloch
Differential effects of competitive and non-competitive N-methyl-D-aspartate antagonists on glucose use in the limbic system.
Neuroscience letters 1988;91(2):204-10.
1988: E Ozyurt; D I Graham; G N Woodruff; James McCulloch
Protective effect of the glutamate antagonist, MK-801 in focal cerebral ischemia in the cat.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1988;8(1):138-43.
1987: I Mhairi Macrae; D I Graham; James McCulloch
Vasomotor effects of atrial natriuretic peptides on feline pial arterioles.
Brain research 1987;435(1-2):195-201.
1987: P A Kelly; James McCulloch
Cerebral glucose utilization following striatal lesions: the effects of the GABA agonist, muscimol, and the dopaminergic agonist, apomorphine.
Brain research 1987;425(2):290-300.
1987: J Reid; James McCulloch
Capsaicin and blood-brain barrier permeability.
Neuroscience letters 1987;81(1-2):165-70.