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Joseph McCune

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Richard M Dunham; Genoveffa Franchini; Shari N Gordon; Yong Huang; Jeffrey Lifson; Michael Piatak; Monica Vaccari; Steven G Deeks; Joseph M McCune
Preclinical evaluation of HIV eradication strategies in the simian immunodeficiency virus-infected rhesus macaque: a pilot study testing inhibition of indoleamine 2,3-dioxygenase.
Steven G Deeks; Eric Verdin; Joseph M McCune
Immunosenescence and HIV.
Urmila D Bajpai; Jonathan D Graf; John B Imboden; Jeff E Mold; Louise A Swainson; Joseph M McCune
A functional variant in FCRL3 is associated with higher Fc receptor-like 3 expression on T cell subsets and rheumatoid arthritis disease activity.

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All Publications

2013: Richard M Dunham; Genoveffa Franchini; Shari N Gordon; Yong Huang; Jeffrey Lifson; Michael Piatak; Monica Vaccari; Steven G Deeks; Joseph M McCune
Preclinical evaluation of HIV eradication strategies in the simian immunodeficiency virus-infected rhesus macaque: a pilot study testing inhibition of indoleamine 2,3-dioxygenase.
AIDS research and human retroviruses 2013;29(2):207-14.
2012: Steven G Deeks; Eric Verdin; Joseph M McCune
Immunosenescence and HIV.
Current opinion in immunology 2012;24(4):501-6.
2012: Urmila D Bajpai; Jonathan D Graf; John B Imboden; Jeff E Mold; Louise A Swainson; Joseph M McCune
A functional variant in FCRL3 is associated with higher Fc receptor-like 3 expression on T cell subsets and rheumatoid arthritis disease activity.
Arthritis and rheumatism 2012;64(8):2451-9.
2012: Dennis J Hartigan-O'Connor; Bittoo Kanwar; Kristina Abel; Koen K A Van Rompay; Joseph M McCune
SIV replication in the infected rhesus macaque is limited by the size of the preexisting TH17 cell compartment.
Science translational medicine 2012;4(136):136ra69.
2012: Karim Sacre; Brigitte Autran; Steven G Deeks; Priscilla Y Hsue; Peter W Hunt; Ekaterina Maidji; Jeffrey N Martin; Joseph M McCune
A role for cytomegalovirus-specific CD4+CX3CR1+ T cells and cytomegalovirus-induced T-cell immunopathology in HIV-associated atherosclerosis.
AIDS (London, England) 2012;26(7):805-14.
2012: Paul D Baum; Michael Busch; Steven Deeks; Rebecca Hoh; Jeffrey Martin; Diane Schmidt; Jennifer J Young; Qianjun Zhang; Joseph M McCune
Blood T-cell receptor diversity decreases during the course of HIV infection, but the potential for a diverse repertoire persists.
Blood 2012;119(15):3469-77.
2012: Mara Jana Broadhurst; Uma Mahesh Gundra; Bittoo Kanwar; Charlie C Kim; Nicholas W Lerche; Jacqueline M Leung; Joseph M McCune; Julie Mirpuri; Ivan Vujkovic-Cvijin; Kirsten E Wiens; Felix Yarovinsky; Amir Ardeshir; P'ng Loke
Therapeutic helminth infection of macaques with idiopathic chronic diarrhea alters the inflammatory signature and mucosal microbiota of the colon.
PLoS pathogens 2012;8(11):e1003000.
2012: Mara J Broadhurst; Padraic G Fallon; Natasha M Girgis; Uma Mahesh Gundra; Jacqueline M Leung; K C Lim; Joseph M McCune; James H McKerrow; Mary Premenko-Lanier; P'ng Loke
Upregulation of retinal dehydrogenase 2 in alternatively activated macrophages during retinoid-dependent type-2 immunity to helminth infection in mice.
PLoS pathogens 2012;8(8):e1002883.
2012: Karim Sacre; Lindsey A Criswell; Joseph M McCune
Hydroxychloroquine is associated with impaired interferon-alpha and tumor necrosis factor-alpha production by plasmacytoid dendritic cells in systemic lupus erythematosus.
Arthritis research & therapy 2012;14(3):R155.
2011: Paul D Baum; Cheryl A Stoddart; Paul M Sullam; Joseph M McCune
Abacavir increases platelet reactivity via competitive inhibition of soluble guanylyl cyclase.
AIDS (London, England) 2011;25(18):2243-8.
2011: Peter Bacchetti; Steven G Deeks; Joseph M McCune
Breaking free of sample size dogma to perform innovative translational research.
Science translational medicine 2011;3(87):87ps24.
2011: Dennis J Hartigan-O'Connor; Lauren A Hirao; Joseph M McCune; Satya Dandekar
Th17 cells and regulatory T cells in elite control over HIV and SIV.
Current opinion in HIV and AIDS 2011;6(3):221-7.
2011: Hiroyu Hatano; Timothy L Hayes; Viktor Dahl; Elizabeth Sinclair; Tzong-Hae Lee; Rebecca Hoh; Harry Lampiris; Peter W Hunt; Sarah Palmer; Joseph M McCune; Jeffrey N Martin; Michael P Busch; Barbara L Shacklett; Steven G Deeks
A randomized, controlled trial of raltegravir intensification in antiretroviral-treated, HIV-infected patients with a suboptimal CD4+ T cell response.
The Journal of infectious diseases 2011;203(7):960-8.
2011: Paul D Baum; Jennifer J Young; Qianjun Zhang; Zeljka Kasakow; Joseph M McCune
Design, construction, and validation of a modular library of sequence diversity standards for polymerase chain reaction.
Analytical biochemistry 2011;411(1):106-15.
2011: David Favre; Cheryl A Stoddart; Brinda Emu; Rebecca Hoh; Jeffrey N Martin; Frederick M Hecht; Steven G Deeks; Joseph M McCune
HIV disease progression correlates with the generation of dysfunctional naive CD8(low) T cells.
Blood 2011;117(7):2189-99.
2011: Jennifer M Babik; Deborah Cohan; Alexander Monto; Dennis J Hartigan-O'Connor; Joseph M McCune
The human fetal immune response to hepatitis C virus exposure in utero.
The Journal of infectious diseases 2011;203(2):196-206.
2011: Peter W Hunt; Alan L Landay; Elizabeth Sinclair; Jeffrey A Martinson; Hiroyu Hatano; Brinda Emu; Philip J Norris; Michael P Busch; Jeffrey N Martin; Cicely Brooks; Joseph M McCune; Steven G Deeks
A low T regulatory cell response may contribute to both viral control and generalized immune activation in HIV controllers.
PloS one 2011;6(1):e15924.
2010: Jeff E Mold; Shivkumar Venkatasubrahmanyam; Trevor D Burt; Jakob Michaëlsson; Jose M Rivera; Sofiya A Galkina; Kenneth Weinberg; Cheryl A Stoddart; Joseph M McCune
Fetal and adult hematopoietic stem cells give rise to distinct T cell lineages in humans.
Science (New York, N.Y.) 2010;330(6011):1695-9.
2010: Mara J Broadhurst; Jacqueline M Leung; Vikram Kashyap; Joseph M McCune; Uma Mahadevan; James H McKerrow; P'ng Loke
IL-22+ CD4+ T cells are associated with therapeutic trichuris trichiura infection in an ulcerative colitis patient.
Science translational medicine 2010;2(60):60ra88.
2010: Steven G Deeks; Joseph M McCune
Can HIV be cured with stem cell therapy?
Nature biotechnology 2010;28(8):807-10.
2010: David Favre; Jeff Mold; Peter W Hunt; Bittoo Kanwar; P'ng Loke; Lillian Seu; Jason D Barbour; Margaret M Lowe; Anura Jayawardene; Francesca T Aweeka; Yong Huang; Daniel C Douek; Jason M Brenchley; Jeffrey N Martin; Frederick Hecht; Steven G Deeks; Joseph M McCune
Tryptophan catabolism by indoleamine 2,3-dioxygenase 1 alters the balance of TH17 to regulatory T cells in HIV disease.
Science translational medicine 2010;2(32):32ra36.
2010: Louise A Swainson; Jeff E Mold; Urmila D Bajpai; Joseph M McCune
Expression of the autoimmune susceptibility gene FcRL3 on human regulatory T cells is associated with dysfunction and high levels of programmed cell death-1.
Journal of immunology (Baltimore, Md. : 1950) 2010;184(7):3639-47.
2010: Bittoo Kanwar; David Favre; Joseph M McCune
Th17 and regulatory T cells: implications for AIDS pathogenesis.
Current opinion in HIV and AIDS 2010;5(2):151-7.
2010: Cheryl A Stoddart; Mary E Keir; Joseph M McCune
IFN-alpha-induced upregulation of CCR5 leads to expanded HIV tropism in vivo.
PLoS pathogens 2010;6(2):e1000766.
2010: David M Naeger; Jeffrey N Martin; Elizabeth Sinclair; Peter W Hunt; David R Bangsberg; Frederick Hecht; Priscilla Y Hsue; Joseph M McCune; Steven G Deeks
Cytomegalovirus-specific T cells persist at very high levels during long-term antiretroviral treatment of HIV disease.
PloS one 2010;5(1):e8886.
2009: Laurence E Cheng; Bittoo Kanwar; Haig Tcheurekdjian; James P Grenert; Mica Muskat; Melvin B Heyman; Joseph M McCune; Diane W Wara
Persistent systemic inflammation and atypical enterocolitis in patients with NEMO syndrome.
Clinical immunology (Orlando, Fla.) 2009;132(1):124-31.
2009: xavier contreras; Marc Schweneker; Ching-Shih Chen; Joseph M McCune; Steven G Deeks; Jeffrey Martin; B Matija Peterlin
Suberoylanilide hydroxamic acid reactivates HIV from latently infected cells.
The Journal of biological chemistry 2009;284(11):6782-9.
2009: Jose Manuel Lozano; David Favre; Zeljka Kasakow; Véronique Mayau; Marie-Thérèse Nugeyre; Thierno Ka; Abdourahmane Faye; Christopher J Miller; Daniel Scott-Algara; Joseph M McCune; Françoise Barré-Sinoussi; Ousmane M Diop; Michaela C Müller-Trutwin
Gag p27-specific B- and T-cell responses in Simian immunodeficiency virus SIVagm-infected African green monkeys.
Journal of virology 2009;83(6):2770-7.
2009: David Favre; Sharon Lederer; Bittoo Kanwar; Zhong-Min Ma; Sean C Proll; Zeljka Kasakow; Jeff Mold; Louise Swainson; Jason D Barbour; Carole R Baskin; Robert Palermo; Ivona Pandrea; Christopher J Miller; Michael G Katze; Joseph M McCune
Critical loss of the balance between Th17 and T regulatory cell populations in pathogenic SIV infection.
PLoS pathogens 2009;5(2):e1000295.
2009: Sharon Lederer; David Favre; Kathie-Anne Walters; Sean C Proll; Bittoo Kanwar; Zeljka Kasakow; Carole R Baskin; Robert Palermo; Joseph M McCune; Michael G Katze
Transcriptional profiling in pathogenic and non-pathogenic SIV infections reveals significant distinctions in kinetics and tissue compartmentalization.
PLoS pathogens 2009;5(2):e1000296.
2009: Hiroyu Hatano; Eric L Delwart; Philip J Norris; Tzong-Hae Lee; Joan Dunn-Williams; Peter W Hunt; Rebecca Hoh; Susan L Stramer; Jeffrey Linnen; Joseph M McCune; Jeffrey N Martin; Michael P Busch; Steven G Deeks
Evidence for persistent low-level viremia in individuals who control human immunodeficiency virus in the absence of antiretroviral therapy.
Journal of virology 2009;83(1):329-35.
2008: Jeff E Mold; Jakob Michaëlsson; Trevor D Burt; Marcus O Muench; Karen Beckerman; Michael P Busch; Tzong-Hae Lee; Douglas F Nixon; Joseph M McCune
Maternal alloantigens promote the development of tolerogenic fetal regulatory T cells in utero.
Science (New York, N.Y.) 2008;322(5907):1562-5.
2008: R Brad Jones; Lishomwa C Ndhlovu; Jason D Barbour; Prameet M Sheth; Aashish R Jha; Brian R Long; Jessica C Wong; Malathy Satkunarajah; Marc Schweneker; Joan M Chapman; Gabor Gyenes; Bahareh Vali; Martin D Hyrcza; Feng Yun Yue; Colin Kovacs; Aref Sassi; Mona Loutfy; Roberta Halpenny; Desmond Persad; Gerald Spotts; Frederick Hecht; Tae-Wook Chun; Joseph M McCune; Rupert Kaul; James M Rini; Douglas F Nixon; Mario A Ostrowski
Tim-3 expression defines a novel population of dysfunctional T cells with highly elevated frequencies in progressive HIV-1 infection.
The Journal of experimental medicine 2008;205(12):2763-79.
2008: Trevor D Burt; Brian Agan; Vincent Marconi; Weijing He; Hemant Kulkharni ; Jeffrey E Mold; Marielle Cavrois; Yadong Huang; Robert W Mahley; Matthew J Dolan; Joseph M McCune; Sunil Ahuja
Apolipoprotein (apo) E4 enhances HIV-1 cell entry in vitro, and the APOE epsilon4/epsilon4 genotype accelerates HIV disease progression.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(25):8718-23.
2008: Kristin Ladell; Marc K Hellerstein; Denise Cesar; Robert Busch; Drina Boban; Joseph M McCune
Central memory CD8+ T cells appear to have a shorter lifespan and reduced abundance as a function of HIV disease progression.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(12):7907-18.
2008: Brinda Emu; Elizabeth Sinclair; Hiroyu Hatano; April Ferre; Barbara L Shacklett; Jeffrey N Martin; Joseph M McCune; Steven G Deeks
HLA class I-restricted T-cell responses may contribute to the control of human immunodeficiency virus infection, but such responses are not always necessary for long-term virus control.
Journal of virology 2008;82(11):5398-407.
2008: Benoît Malleret; Ingrid Karlsson; Benjamin Manéglier; Patricia Brochard; Benoit Delache; THIBAULT ANDRIEU; Michaela Muller-Trutwin; Tim Beaumont; Joseph M McCune; Jacques Banchereau; Roger Le Grand; Bruno VASLIN
Effect of SIVmac infection on plasmacytoid and CD1c+ myeloid dendritic cells in cynomolgus macaques.
Immunology 2008;124(2):223-33.
2008: Marc Schweneker; David Favre; Jeffrey N Martin; Steven G Deeks; Joseph M McCune
HIV-induced changes in T cell signaling pathways.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(10):6490-500.
2008: Laura A Napolitano; Diane Schmidt; Michael B Gotway; Niloufar Ameli; Erin L Filbert; Myra M Ng; Julie L Clor; Lorrie Epling; Elizabeth Sinclair; Paul D Baum; Kai Li; Marisela Lua Killian; Peter Bacchetti; Joseph M McCune
Growth hormone enhances thymic function in HIV-1-infected adults.
The Journal of clinical investigation 2008;118(3):1085-98.
2008: Michelle E Roland; B Barin; Laurie Carlson; Lynda Frassetto; Norah A Terrault; Ryutaro Hirose; Chris E Freise; Leslie Z Benet; Nancy L Ascher; John P Roberts; B Murphy; Marla Keller; Kim M Olthoff; Emily A Blumberg; K L Brayman; Stephen T Bartlett; Charles Davis; Joseph M McCune; Barry M Bredt; D M Stablein; Peter G Stock
HIV-infected liver and kidney transplant recipients: 1- and 3-year outcomes.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2008;8(2):355-65.
2008: Peter W Hunt; Jason Brenchley; Elizabeth Sinclair; Joseph M McCune; Michelle Roland; Kimberly Page-Shafer; Priscilla Y Hsue; Brinda Emu; Melissa R Krone; Harry Lampiris; Daniel Douek; Jeffrey N Martin; Steven G Deeks
Relationship between T cell activation and CD4+ T cell count in HIV-seropositive individuals with undetectable plasma HIV RNA levels in the absence of therapy.
The Journal of infectious diseases 2008;197(1):126-33.
2008: Bittoo Kanwar; Dong Wei Gao; Andrew B Hwang; James P Grenert; Simon P Williams; Benjamin Franc; Joseph M McCune
In vivo imaging of mucosal CD4+ T cells using single photon emission computed tomography in a murine model of colitis.
Journal of immunological methods 2008;329(1-2):21-30.
2007: Dennis J Hartigan-O'Connor; Kristina Abel; Joseph M McCune
Suppression of SIV-specific CD4+ T cells by infant but not adult macaque regulatory T cells: implications for SIV disease progression.
The Journal of experimental medicine 2007;204(11):2679-92.
2007: Rachel E Owen; Elizabeth Sinclair; Brinda Emu; John W Heitman; Dale F Hirschkorn; C Lorrie Epling; Qi Xuan Tan; Brian Custer; Jeffery M Harris; Mark A Jacobson; Joseph M McCune; Jeffrey N Martin; Frederick Hecht; Steven G Deeks; Philip J Norris
Loss of T cell responses following long-term cryopreservation.
Journal of immunological methods 2007;326(1-2):93-115.
2007: Christopher J Miller; Meritxell Genescà; Kristina Abel; David Montefiori; Donald N Forthal; Kristen Bost; Jun Li; David Favre; Joseph M McCune
Antiviral antibodies are necessary for control of simian immunodeficiency virus replication.
Journal of virology 2007;81(10):5024-35.
2007: Dennis J Hartigan-O'Connor; Chungkee Poon; Elizabeth Sinclair; Joseph M McCune
Human CD4+ regulatory T cells express lower levels of the IL-7 receptor alpha chain (CD127), allowing consistent identification and sorting of live cells.
Journal of immunological methods 2007;319(1-2):41-52.
2007: Donald I Abrams; Starley B Shade; Paul Couey; Joseph M McCune; Joan Lo; Peter Bacchetti; Barbara Chang; Lorrie Epling; Teri Liegler; Robert M Grant
Dehydroepiandrosterone (DHEA) effects on HIV replication and host immunity: a randomized placebo-controlled study.
AIDS research and human retroviruses 2007;23(1):77-85.
2006: Priscilla Y Hsue; Peter W Hunt; Elizabeth Sinclair; Barry M Bredt; Arlana Franklin; Maudi Killian; Rebecca Hoh; Jeffrey N Martin; Joseph M McCune; David D Waters; Steven G Deeks
Increased carotid intima-media thickness in HIV patients is associated with increased cytomegalovirus-specific T-cell responses.
AIDS (London, England) 2006;20(18):2275-83.
2006: Sunil Ahuja; Fernando Aiuti; Ben Berkhout; Peter Biberfeld; Dennis R Burton; Vittorio Colizzi; Steven G Deeks; Ronald C Desrosiers; Manfred P Dierich; Robert W Doms; Michael Emerman; Robert C Gallo; Marc Girard; Warner Greene; James A Hoxie; Eric Hunter; George Klein; Bette Korber; Daniel R Kuritzkes; Michael M Lederman; Michael H Malim; Preston A Marx; Joseph M McCune; Andrew McMichael; Christopher J Miller; Veronica Miller; Luc Montagnier; David C Montefiori; John P Moore; Douglas F Nixon; Julie Overbaugh; C. David Pauza; Douglas D Richman; Michael S Saag; Quentin Sattentau; Robert T Schooley; Robin Shattock; George M Shaw; Mario Stevenson; Alexandra Trkola; Mark A Wainberg; Robin A Weiss; Steven Wolinsky; Jerome A Zack
A plea for justice for jailed medical workers.
Science (New York, N.Y.) 2006;314(5801):924-5.
2006: Paul D Baum; Joseph M McCune
Direct measurement of T-cell receptor repertoire diversity with AmpliCot.
Nature methods 2006;3(11):895-901.
2006: Kristy Red-Horse; Jose Rivera; Andrea Schanz; Yan Zhou; Virginia D Winn; Mirhan Kapidzic; Emin Maltepe; Kelly Okazaki; Ronit Kochman; Kim Chi Vo; Linda C Giudice; Adrian Erlebacher; Joseph M McCune; Cheryl A Stoddart; Susan J Fisher
Cytotrophoblast induction of arterial apoptosis and lymphangiogenesis in an in vivo model of human placentation.
The Journal of clinical investigation 2006;116(10):2643-52.
2006: Peter W Hunt; P Richard Harrigan; Wei Huang; Michael Bates; David W Williamson; Joseph M McCune; Richard W Price; Serena S Spudich; Harry Lampiris; Rebecca Hoh; Teri Leigler; Jeffrey N Martin; Steven G Deeks
Prevalence of CXCR4 tropism among antiretroviral-treated HIV-1-infected patients with detectable viremia.
The Journal of infectious diseases 2006;194(7):926-30.
2006: Steven G Deeks; Becky Schweighardt; Terri Wrin; Justin Galovich; Rebecca Hoh; Elizabeth Sinclair; Peter Hunt; Joseph M McCune; Jeffrey N Martin; Christos J Petropoulos; Frederick Hecht
Neutralizing antibody responses against autologous and heterologous viruses in acute versus chronic human immunodeficiency virus (HIV) infection: evidence for a constraint on the ability of HIV to completely evade neutralizing antibody responses.
Journal of virology 2006;80(12):6155-64.
2006: Jakob Michaëlsson; Jeff E Mold; Joseph M McCune; Douglas F Nixon
Regulation of T cell responses in the developing human fetus.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(10):5741-8.
2006: Kristy Red-Horse; J Rivera; Andrea Schanz; Y Zhou; Virginia D Winn; Mirhan Kapidzic; Emin Maltepe; K Okazaki; R Kochman; Kim Chi Vo; Linda C Giudice; A Erlebacher; Joseph M McCune; Cheryl A Stoddart; S J Fisher
Literature watch. Cytotrophoblast induction of arterial apoptosis and lymphangiogenesis in an in vivo model of human placentation.
Lymphatic research and biology 2006;4(4):229-42.
2006: Laurel E Nomura; Brinda Emu; Rebecca Hoh; Perry Haaland; Steven G Deeks; Jeffrey N Martin; Joseph M McCune; Douglas F Nixon; Holden T Maecker
IL-2 production correlates with effector cell differentiation in HIV-specific CD8+ T cells.
AIDS research and therapy 2006;3():18.
2006: Emmanouil Papasavvas; Jay R Kostman; Brian Thiel; Maxwell Pistilli; Agnieszka Mackiewicz; Andrea S Foulkes; Robert Gross; Kimberly A Jordan; Douglas F Nixon; Robert Grant; Jean-Francois Poulin; Joseph M McCune; Karam Mounzer; Luis J Montaner
HIV-1-specific CD4+ T cell responses in chronically HIV-1 infected blippers on antiretroviral therapy in relation to viral replication following treatment interruption.
Journal of clinical immunology 2006;26(1):40-54.
2005: Laura A Napolitano; Trevor D Burt; Peter Bacchetti; Yolanda Barrón; Audrey L French; Andrea Kovacs; Kathryn Anastos; Mary Young; Joseph M McCune; Ruth M Greenblatt
Increased circulating interleukin-7 levels in HIV-1-infected women.
Journal of acquired immune deficiency syndromes (1999) 2005;40(5):581-4.
2005: Peter K Wung; Janet T Holbrook; Gary S Hoffman; Andrea K Tibbs; Ulrich Specks; Yuan-I Min; Peter A Merkel; Robert Spiera; John C Davis; E William St Clair; Joseph M McCune; Steven R Ytterberg; Nancy B Allen; John H Stone
Herpes zoster in immunocompromised patients: incidence, timing, and risk factors.
The American journal of medicine 2005;118(12):1416.
2005: Brinda Emu; Elizabeth Sinclair; David Favre; Walter J Moretto; Priscilla Hsue; Rebecca Hoh; Jeffrey N Martin; Douglas F Nixon; Joseph M McCune; Steven G Deeks
Phenotypic, functional, and kinetic parameters associated with apparent T-cell control of human immunodeficiency virus replication in individuals with and without antiretroviral treatment.
Journal of virology 2005;79(22):14169-78.
2005: Ann-Marie Roy; Becky Schweighardt; Lauren A Eckstein; Mark A Goldsmith; Joseph M McCune
Enhanced replication of R5 HIV-1 over X4 HIV-1 in CD4(+)CCR5(+)CXCR4(+) T cells.
Journal of acquired immune deficiency syndromes (1999) 2005;40(3):267-75.
2005: Mary Beth Hanley; Laura A Napolitano; Joseph M McCune
Growth hormone-induced stimulation of multilineage human hematopoiesis.
Stem cells (Dayton, Ohio) 2005;23(8):1170-9.
2005: Jeffrey M Harris; Mette D Hazenberg; Jean-François Poulin; Dana Higuera-Alhino; Diane Schmidt; Michael B Gotway; Joseph M McCune
Multiparameter evaluation of human thymic function: interpretations and caveats.
Clinical immunology (Orlando, Fla.) 2005;115(2):138-46.
2005: John H Stone; Vinodh N Rajapakse; Gary S Hoffman; Ulrich Specks; Peter A Merkel; Robert Spiera; John C Davis; E William St Clair; Joseph M McCune; Sally Ross; Ben A Hitt; Timothy D Veenstra; Thomas P Conrads; Lance A Liotta; Emanuel F Petricoin
A serum proteomic approach to gauging the state of remission in Wegener's granulomatosis.
Arthritis and rheumatism 2005;52(3):902-10.
2004: Kimberly Smith; Evgenia Aga; Ronald J Bosch; Hernan Valdez; Elizabeth Connick; Alan Landay; Daniel R Kuritzkes; Barry H Gross; Isaac R Francis; Joseph M McCune; Harold Kessler; Michael M Lederman
Long-term changes in circulating CD4 T lymphocytes in virologically suppressed patients after 6 years of highly active antiretroviral therapy.
AIDS (London, England) 2004;18(14):1953-6.
2004: Myeong Sup Lee; Kristina Hanspers; Christopher S Barker; Abner P Korn; Joseph M McCune
Gene expression profiles during human CD4+ T cell differentiation.
International immunology 2004;16(8):1109-24.
2004: Robert Busch; Denise Cesar; Dana Higuera-Alhino; Tracy Gee; Marc K Hellerstein; Joseph M McCune
Isolation of peripheral blood CD4(+) T cells using RosetteSep and MACS for studies of DNA turnover by deuterium labeling.
Journal of immunological methods 2004;286(1-2):97-109.
2004: Dennis R Burton; Ronald C Desrosiers; Robert W Doms; Mark B Feinberg; Robert C Gallo; Beatrice Hahn; James A Hoxie; Eric Hunter; Bette Korber; Alan Landay; Michael M Lederman; Judy Lieberman; Joseph M McCune; John P Moore; Neal Nathanson; Louis J Picker; Douglas Richman; Charles Rinaldo; Mario Stevenson; David Ian Watkins; Steven M Wolinsky; Jerome A Zack
Public health. A sound rationale needed for phase III HIV-1 vaccine trials.
Science (New York, N.Y.) 2004;303(5656):316.
2004: Steven G Deeks; Jeffrey N Martin; Elizabeth Sinclair; Jeff Harris; Torsten B Neilands; Holden T Maecker; Elilta Hagos; Terri Wrin; Christos J Petropoulos; Barry M Bredt; Joseph M McCune
Strong cell-mediated immune responses are associated with the maintenance of low-level viremia in antiretroviral-treated individuals with drug-resistant human immunodeficiency virus type 1.
The Journal of infectious diseases 2004;189(2):312-21.
2004: J E Jennings; Pia C Sundgren; John Attwood; Joseph M McCune; Pavel V Maly
Value of MRI of the brain in patients with systemic lupus erythematosus and neurologic disturbance.
Neuroradiology 2004;46(1):15-21.
2003: Annika C Karlsson; Jeffrey N Martin; Sophie R Younger; Barry M Bredt; Lorrie Epling; Rollie Ronquillo; Arjun Varma; Steven G Deeks; Joseph M McCune; Douglas F Nixon; Elizabeth Sinclair
Comparison of the ELISPOT and cytokine flow cytometry assays for the enumeration of antigen-specific T cells.
Journal of immunological methods 2003;283(1-2):141-53.
2003: Marc K Hellerstein; Rebecca Hoh; Mary Beth Hanley; Denise Cesar; Daniel Lee; Richard A Neese; Joseph M McCune
Subpopulations of long-lived and short-lived T cells in advanced HIV-1 infection.
The Journal of clinical investigation 2003;112(6):956-66.
2003: Donald I Abrams; Joan F Hilton; Roslyn J Leiser; Starley B Shade; Tarek Elbeik; Francesca T Aweeka; Neal L Benowitz; Barry M Bredt; Bradley W Kosel; Judith A Aberg; Steven G Deeks; Thomas F Mitchell; Kathleen Mulligan; Peter Bacchetti; Joseph M McCune; Morris Schambelan
Short-term effects of cannabinoids in patients with HIV-1 infection: a randomized, placebo-controlled clinical trial.
Annals of internal medicine 2003;139(4):258-66.
2003: Laura A Napolitano; Cheryl A Stoddart; Mary Beth Hanley; Eric Wieder; Joseph M McCune
Effects of IL-7 on early human thymocyte progenitor cells in vitro and in SCID-hu Thy/Liv mice.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(2):645-54.
2003: Cheryl A Stoddart; Romas Geleziunas; Sharon Ferrell; Valerie Linquist-Stepps; Mary E Moreno; Christopher Bare; Weiduan Xu; Wes Yonemoto; Patricia A Bresnahan; Joseph M McCune; Warner Greene
Human immunodeficiency virus type 1 Nef-mediated downregulation of CD4 correlates with Nef enhancement of viral pathogenesis.
Journal of virology 2003;77(3):2124-33.
2002: Richard A Neese; Lisa M Misell; S Turner; Alice Chu; Joseph Kim; Denise Cesar; Rebecca Hoh; F Antelo; A Strawford; Joseph M McCune; MP Christiansen; Marc K Hellerstein
Measurement in vivo of proliferation rates of slow turnover cells by 2H2O labeling of the deoxyribose moiety of DNA.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(24):15345-50.
2002: Barry M Bredt; Dana Higuera-Alhino; Starley B Shade; Samuel J Hebert; Joseph M McCune; Donald I Abrams
Short-term effects of cannabinoids on immune phenotype and function in HIV-1-infected patients.
Journal of clinical pharmacology 2002;42(11 Suppl):82S-89S.
2002: Mary E Keir; Michael G Rosenberg; Johan K Sandberg; Kimberly A Jordan; Andrew Wiznia; Douglas F Nixon; Cheryl A Stoddart; Joseph M McCune
Generation of CD3+CD8low thymocytes in the HIV type 1-infected thymus.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(5):2788-96.
2002: Mark B Feinberg; Joseph M McCune; Frank Miedema; John P Moore; Hanneke Schuitemaker
HIV tropism and CD4+ T-cell depletion.
Nature medicine 2002;8(6):537.
2002: Laura A Napolitano; Joan C Lo; Michael B Gotway; Kathleen Mulligan; Jason D Barbour; Diane Schmidt; Robert M Grant; Robert A Halvorsen; Morris Schambelan; Joseph M McCune
Increased thymic mass and circulating naive CD4 T cells in HIV-1-infected adults treated with growth hormone.
AIDS (London, England) 2002;16(8):1103-11.
2002: Steven G Deeks; Rebecca Hoh; Robert M Grant; Terri Wrin; Jason D Barbour; Amy Narvaez; Denise Cesar; Ken Abe; Mary Beth Hanley; Nicholas S Hellmann; Christos J Petropoulos; Joseph M McCune; Marc K Hellerstein
CD4+ T cell kinetics and activation in human immunodeficiency virus-infected patients who remain viremic despite long-term treatment with protease inhibitor-based therapy.
The Journal of infectious diseases 2002;185(3):315-23.
2002: Mary E Keir; Cheryl A Stoddart; Valerie Linquist-Stepps; Mary E Moreno; Joseph M McCune
IFN-alpha secretion by type 2 predendritic cells up-regulates MHC class I in the HIV-1-infected thymus.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(1):325-31.
2001: L Teixeira; Hernan Valdez; Joseph M McCune; Richard A Koup; andrew badley; Marc K Hellerstein; Laura A Napolitano; Daniel C Douek; Georgina Mbisa; Steven Deeks; J M Harris; Jason D Barbour; Barry H Gross; Isaac R Francis; Robert A Halvorsen; Robert Asaad; Michael M Lederman
Poor CD4 T cell restoration after suppression of HIV-1 replication may reflect lower thymic function.
AIDS (London, England) 2001;15(14):1749-56.
2001: Holden T Maecker; Holli S Dunn; Maria A Suni; Elham Khatamzas; Christine J Pitcher; Torsten Bunde; Natasha Persaud; Wendy Trigona; Tong-Ming Fu; Elizabeth Sinclair; Barry M Bredt; Joseph M McCune; Vernon C Maino; Florian Kern; Louis J Picker
Use of overlapping peptide mixtures as antigens for cytokine flow cytometry.
Journal of immunological methods 2001;255(1-2):27-40.
2001: Cheryl A Stoddart; Teri Liegler; F Mammano; Valerie Linquist-Stepps; Matthew Hayden; Steven G Deeks; Robert M Grant; F Clavel; Joseph M McCune
Impaired replication of protease inhibitor-resistant HIV-1 in human thymus.
Nature medicine 2001;7(6):712-8.
2001: Mark A Jacobson; R Schrier; Joseph M McCune; Francesca J Torriani; Gary N Holland; JJ O'Donnell; W R Freeman; Barry M Bredt
Cytomegalovirus (CMV)-specific CD4+ T lymphocyte immune function in long-term survivors of AIDS-related CMV end-organ disease who are receiving potent antiretroviral therapy.
The Journal of infectious diseases 2001;183(9):1399-404.
2001: Joseph M McCune
The dynamics of CD4+ T-cell depletion in HIV disease.
Nature 2001;410(6831):974-9.
2001: Krishna Komanduri; J Feinberg; R K Hutchins; R D Frame; DK Schmidt; M N Viswanathan; Jacob P Lalezari; Joseph M McCune
Loss of cytomegalovirus-specific CD4+ T cell responses in human immunodeficiency virus type 1-infected patients with high CD4+ T cell counts and recurrent retinitis.
The Journal of infectious diseases 2001;183(8):1285-9.
2001: Steven G Deeks; Terri Wrin; Teri Liegler; Rebecca Hoh; Matthew Hayden; Jason D Barbour; Nicholas S Hellmann; Christos J Petropoulos; Joseph M McCune; Marc K Hellerstein; Robert M Grant
Virologic and immunologic consequences of discontinuing combination antiretroviral-drug therapy in HIV-infected patients with detectable viremia.
The New England journal of medicine 2001;344(7):472-80.
2001: Krishna Komanduri; Sean M Donahoe; Walter J Moretto; DK Schmidt; G Gillespie; Graham S Ogg; M Roederer; Douglas F Nixon; Joseph M McCune
Direct measurement of CD4+ and CD8+ T-cell responses to CMV in HIV-1-infected subjects.
Virology 2001;279(2):459-70.
2001: Krishna Komanduri; Joseph M McCune
The diversity of T cells.
The New England journal of medicine 2001;344(3):231-2.
2001: Laura A Napolitano; Robert M Grant; Steven G Deeks; Diane Schmidt; S C De Rosa; L A Herzenberg; Brian G Herndier; J Andersson; Joseph M McCune
Increased production of IL-7 accompanies HIV-1-mediated T-cell depletion: implications for T-cell homeostasis.
Nature medicine 2001;7(1):73-9.
2000: A Gobbi; Cheryl A Stoddart; Giuseppe Locatelli; Fabio Santoro; Christopher Bare; Valerie Linquist-Stepps; Mary E Moreno; Nancy W Abbey; Brian G Herndier; Mauro S Malnati; Joseph M McCune; Paolo Lusso
Coinfection of SCID-hu Thy/Liv mice with human herpesvirus 6 and human immunodeficiency virus type 1.
Journal of virology 2000;74(18):8726-31.
2000: RD Berkowitz; S Alexander; Joseph M McCune
Causal relationships between HIV-1 coreceptor utilization, tropism, and pathogenesis in human thymus.
AIDS research and human retroviruses 2000;16(11):1039-45.
2000: P Schlegel; P Beatty; R Halvorsen; Joseph M McCune
Successful allogeneic bone marrow transplant in an HIV-1-positive man with chronic myelogenous leukemia.
Journal of acquired immune deficiency syndromes (1999) 2000;24(3):289-90.
2000: Morgan R Jenkins; Mary E Keir; Joseph M McCune
A membrane-bound Fas decoy receptor expressed by human thymocytes.
The Journal of biological chemistry 2000;275(11):7988-93.
2000: S S Huang; Jason D Barbour; Steven G Deeks; Jeannie S Huang; Robert M Grant; V L Ng; Joseph M McCune
Reversal of human immunodeficiency virus type 1-associated hematosuppression by effective antiretroviral therapy.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2000;30(3):504-10.
2000: Joseph M McCune; Mary Beth Hanley; Denise Cesar; Robert A Halvorsen; Rebecca Hoh; D Schmidt; Eric Wieder; Steven Deeks; SQ Siler; Richard A Neese; Marc K Hellerstein
Factors influencing T-cell turnover in HIV-1-seropositive patients.
The Journal of clinical investigation 2000;105(5):R1-8.
2000: Cheryl A Stoddart; Mary E Moreno; Valerie Linquist-Stepps; Christopher Bare; Mark Bogan; A Gobbi; R W Buckheit; J Bedard; RF Rando; Joseph M McCune
Antiviral activity of 2'-deoxy-3'-oxa-4'-thiocytidine (BCH-10652) against lamivudine-resistant human immunodeficiency virus type 1 in SCID-hu Thy/Liv mice.
Antimicrobial agents and chemotherapy 2000;44(3):783-6.
2000: Kimberly Y Smith; Hernan Valdez; Alan Landay; John Spritzler; Harold A Kessler; Elizabeth Connick; Daniel R Kuritzkes; Barry H Gross; Isaac R Francis; Joseph M McCune; Michael M Lederman
Thymic size and lymphocyte restoration in patients with human immunodeficiency virus infection after 48 weeks of zidovudine, lamivudine, and ritonavir therapy.
The Journal of infectious diseases 2000;181(1):141-7.
1999: Dirk P Dittmer; Cheryl A Stoddart; Rolf Renne; Valerie Linquist-Stepps; Mary E Moreno; Christopher Bare; Joseph M McCune; Don Ganem
Experimental transmission of Kaposi's sarcoma-associated herpesvirus (KSHV/HHV-8) to SCID-hu Thy/Liv mice.
The Journal of experimental medicine 1999;190(12):1857-68.
1999: RD Berkowitz; Angelica B Van't Wout; Neeltje Kootstra; Mary E Moreno; Valerie Linquist-Stepps; Christopher Bare; Cheryl A Stoddart; Hanneke Schuitemaker; Joseph M McCune
R5 strains of human immunodeficiency virus type 1 from rapid progressors lacking X4 strains do not possess X4-type pathogenicity in human thymus.
Journal of virology 1999;73(9):7817-22.
1999: Jean-François Poulin; M N Viswanathan; J M Harris; Krishna Komanduri; Eric Wieder; N Ringuette; Morgan R Jenkins; Joseph M McCune; Rafick-Pierre Sékaly
Direct evidence for thymic function in adult humans.
The Journal of experimental medicine 1999;190(4):479-86.
1999: Morgan R Jenkins; Mary E Keir; Joseph M McCune
Fas is expressed early in human thymocyte development but does not transmit an apoptotic signal.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(3):1195-204.
1999: A Gobbi; Cheryl A Stoddart; Mauro S Malnati; Giuseppe Locatelli; Fabio Santoro; Nancy W Abbey; Christopher Bare; Valerie Linquist-Stepps; M B Moreno; Brian G Herndier; Paolo Lusso; Joseph M McCune
Human herpesvirus 6 (HHV-6) causes severe thymocyte depletion in SCID-hu Thy/Liv mice.
The Journal of experimental medicine 1999;189(12):1953-60.
1999: G Kovalev; K Duus; L Wang; R Lee; ML Bonyhadi; D Ho; Joseph M McCune; H Kaneshima; Lishan Su
Induction of MHC class I expression on immature thymocytes in HIV-1-infected SCID-hu Thy/Liv mice: evidence of indirect mechanisms.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(12):7555-62.
1999: Marc K Hellerstein; M B Hanley; Denise Cesar; SQ Siler; C Papageorgopoulos; Eric Wieder; D Schmidt; Rebecca Hoh; Richard A Neese; D Macallan; Steven Deeks; Joseph M McCune
Directly measured kinetics of circulating T lymphocytes in normal and HIV-1-infected humans.
Nature medicine 1999;5(1):83-9.
1998: RD Berkowitz; S Alexander; Christopher Bare; Valerie Linquist-Stepps; Mark Bogan; Mary E Moreno; L Gibson; Eric Wieder; J Kosek; Cheryl A Stoddart; Joseph M McCune
CCR5- and CXCR4-utilizing strains of human immunodeficiency virus type 1 exhibit differential tropism and pathogenesis in vivo.
Journal of virology 1998;72(12):10108-17.
1998: RD Berkowitz; Karen Beckerman; T J Schall; Joseph M McCune
CXCR4 and CCR5 expression delineates targets for HIV-1 disruption of T cell differentiation.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(7):3702-10.
1998: Krishna Komanduri; M N Viswanathan; Eric Wieder; DK Schmidt; Barry M Bredt; Mark A Jacobson; Joseph M McCune
Restoration of cytomegalovirus-specific CD4+ T-lymphocyte responses after ganciclovir and highly active antiretroviral therapy in individuals infected with HIV-1.
Nature medicine 1998;4(8):953-6.
1998: Cheryl A Stoddart; L Rabin; M Hincenbergs; M Moreno; Valerie Linquist-Stepps; J M Leeds; L A Truong; Jacqueline R Wyatt; David J Ecker; Joseph M McCune
Inhibition of human immunodeficiency virus type 1 infection in SCID-hu Thy/Liv mice by the G-quartet-forming oligonucleotide, ISIS 5320.
Antimicrobial agents and chemotherapy 1998;42(8):2113-5.
1998: Joseph M McCune; Richard A Loftus; DK Schmidt; P Carroll; D Webster; L B Swor-Yim; Isaac R Francis; Barry H Gross; Robert M Grant
High prevalence of thymic tissue in adults with human immunodeficiency virus-1 infection.
The Journal of clinical investigation 1998;101(11):2301-8.
1998: Morgan R Jenkins; Mary Beth Hanley; M B Moreno; Eric Wieder; Joseph M McCune
Human immunodeficiency virus-1 infection interrupts thymopoiesis and multilineage hematopoiesis in vivo.
Blood 1998;91(8):2672-8.
1998: R Namikawa; H Kaneshima; Joseph M McCune
Furry flasks?
Nature biotechnology 1998;16(4):314.
1998: V Linquist; Cheryl A Stoddart; Joseph M McCune
UV irradiation of polystyrene pipets releases PCR inhibitors.
BioTechniques 1998;24(1):50-2.
1997: Joseph M McCune
Animal models of HIV-1 disease.
Science (New York, N.Y.) 1997;278(5346):2141-2.
1997: Joseph M McCune
Thymic function in HIV-1 disease.
Seminars in immunology 1997;9(6):397-404.
1997: M K Hellerstein; Joseph M McCune
T cell turnover in HIV-1 disease.
Immunity 1997;7(5):583-9.
1997: Joseph M McCune; N G Singer
Immunosuppressive drug treatment.
Current opinion in rheumatology 1997;9(3):191-9.
1997: Krishna Komanduri; M D Salha; Rafick-Pierre Sékaly; Joseph M McCune
Superantigen-mediated deletion of specific T cell receptor V beta subsets in the SCID-hu Thy/Liv mouse is induced by staphylococcal enterotoxin B, but not HIV-1.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(2):544-9.
1997: Lishan Su; H Kaneshima; ML Bonyhadi; R Lee; J Auten; A Wolf; B Du; L Rabin; B H Hahn; E Terwilliger; Joseph M McCune
Identification of HIV-1 determinants for replication in vivo.
Virology 1997;227(1):45-52.
1996: Joseph M McCune
Development and applications of the SCID-hu mouse model.
Seminars in immunology 1996;8(4):187-96.
1996: Paul Auwaerter; H Kaneshima; Joseph M McCune; G Wiegand; Diane E Griffin
Measles virus infection of thymic epithelium in the SCID-hu mouse leads to thymocyte apoptosis.
Journal of virology 1996;70(6):3734-40.
1996: L Rabin; M Hincenbergs; M B Moreno; S Warren; V Linquist; R Datema; B Charpiot; J Seifert; H Kaneshima; Joseph M McCune
Use of standardized SCID-hu Thy/Liv mouse model for preclinical efficacy testing of anti-human immunodeficiency virus type 1 compounds.
Antimicrobial agents and chemotherapy 1996;40(3):755-62.
1996: R Datema; L Rabin; M Hincenbergs; M B Moreno; S Warren; V Linquist; B Rosenwirth; J Seifert; Joseph M McCune
Antiviral efficacy in vivo of the anti-human immunodeficiency virus bicyclam SDZ SID 791 (JM 3100), an inhibitor of infectious cell entry.
Antimicrobial agents and chemotherapy 1996;40(3):750-4.
1996: Joseph M McCune
HIV and the cells it infects: sorting the latent from the labile. An interview with Mike McCune, MD, PhD. Interview by Mark Mascolini.
Journal of the International Association of Physicians in AIDS Care 1996;2(1):20-2, 25-7, 41.
1995: ML Bonyhadi; Lishan Su; J Auten; Joseph M McCune; H Kaneshima
Development of a human thymic organ culture model for the study of HIV pathogenesis.
AIDS research and human retroviruses 1995;11(9):1073-80.
1995: Joseph M McCune
Viral latency in HIV disease.
Cell 1995;82(2):183-8.
1995: Lishan Su; H Kaneshima; ML Bonyhadi; S Salimi; D Kraft; L Rabin; Joseph M McCune
HIV-1-induced thymocyte depletion is associated with indirect cytopathogenicity and infection of progenitor cells in vivo.
Immunity 1995;2(1):25-36.
1994: H Kaneshima; Lishan Su; ML Bonyhadi; R I Connor; D D Ho; Joseph M McCune
Rapid-high, syncytium-inducing isolates of human immunodeficiency virus type 1 induce cytopathicity in the human thymus of the SCID-hu mouse.
Journal of virology 1994;68(12):8188-92.
1994: H Kaneshima; R Namikawa; Joseph M McCune
Human hematolymphoid cells in SCID mice.
Current opinion in immunology 1994;6(2):327-33.
1994: Leon G Epstein; T A Cvetkovich; E S Lazar; David A DiLoreto; Y Saito; H James; C del Cerro; H Kaneshima; Joseph M McCune; W J Britt
Human neural xenografts: progress in developing an in-vivo model to study human immunodeficiency virus (HIV) and human cytomegalovirus (HCMV) infection.
Advances in neuroimmunology 1994;4(3):257-60.
1994: S Kyoizumi; Joseph M McCune; R Namikawa
Direct evaluation of radiation damage in human hematopoietic progenitor cells in vivo.
Radiation research 1994;137(1):76-83.
1993: S K Stanley; Joseph M McCune; H Kaneshima; J S Justement; M Sullivan; E Boone; Michael Baseler; Joseph W Adelsberger; ML Bonyhadi; Jan M Orenstein
Human immunodeficiency virus infection of the human thymus and disruption of the thymic microenvironment in the SCID-hu mouse.
The Journal of experimental medicine 1993;178(4):1151-63.
1993: ML Bonyhadi; L Rabin; S Salimi; D A Brown; J Kosek; Joseph M McCune; H Kaneshima
HIV induces thymus depletion in vivo.
Nature 1993;363(6431):728-32.
1993: Edward Mocarski; ML Bonyhadi; S Salimi; Joseph M McCune; H Kaneshima
Human cytomegalovirus in a SCID-hu mouse: thymic epithelial cells are prominent targets of viral replication.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(1):104-8.
1992: S Kyoizumi; C M Baum; H Kaneshima; Joseph M McCune; E J Yee; R Namikawa
Implantation and maintenance of functional human bone marrow in SCID-hu mice.
Blood 1992;79(7):1704-11.
1992: Joseph M McCune
The SCID-hu mouse: a small animal model for the analysis of human hematolymphoid differentiation and function.
Bone marrow transplantation 1992;9 Suppl 1():74-6.
1991: Joseph M McCune; B Péault; Philip R Streeter; L Rabin
Preclinical evaluation of human hematolymphoid function in the SCID-hu mouse.
Immunological reviews 1991;124():45-62.
1991: B Péault; I L Weissman; C Baum; Joseph M McCune; Ann Tsukamoto
Lymphoid reconstitution of the human fetal thymus in SCID mice with CD34+ precursor cells.
The Journal of experimental medicine 1991;174(5):1283-6.
1991: Joseph M McCune
Epstein-Barr virus associated lymphoproliferative disease in mice and men.
Laboratory investigation; a journal of technical methods and pathology 1991;65(4):377-80.
1991: B A Vandekerckhove; J F Krowka; Joseph M McCune; J E de Vries; H Spits; Maria-Grazia Roncarolo
Clonal analysis of the peripheral T cell compartment of the SCID-hu mouse.
Journal of immunology (Baltimore, Md. : 1950) 1991;146(12):4173-9.
1991: J F Krowka; S Sarin; R Namikawa; Joseph M McCune; H Kaneshima
Human T cells in the SCID-hu mouse are phenotypically normal and functionally competent.
Journal of immunology (Baltimore, Md. : 1950) 1991;146(11):3751-6.
1991: H Kaneshima; C C Shih; R Namikawa; L Rabin; H Outzen; S G Machado; Joseph M McCune
Human immunodeficiency virus infection of human lymph nodes in the SCID-hu mouse.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(10):4523-7.
1991: Joseph M McCune
SCID mice as immune system models.
Current opinion in immunology 1991;3(2):224-8.
1991: C C Shih; H Kaneshima; L Rabin; R Namikawa; P Sager; J McGowan; Joseph M McCune
Postexposure prophylaxis with zidovudine suppresses human immunodeficiency virus type 1 infection in SCID-hu mice in a time-dependent manner.
The Journal of infectious diseases 1991;163(3):625-7.
1991: Joseph M McCune
HIV-1: the infective process in vivo.
Cell 1991;64(2):351-63.
1991: Joseph M McCune; H Kaneshima; J Krowka; R Namikawa; H Outzen; B Peault; L Rabin; C C Shih; E Yee; M Lieberman
The SCID-hu mouse: a small animal model for HIV infection and pathogenesis.
Annual review of immunology 1991;9():399-429.
1990: H Kaneshima; C Baum; B Chen; R Namikawa; H Outzen; L Rabin; A Tsukamoto; Joseph M McCune
Today's SCID-hu mouse.
Nature 1990;348(6301):561-2.
1990: Joseph M McCune; R Namikawa; C C Shih; L Rabin; H Kaneshima
Pseudotypes in HIV-infected mice.
Science (New York, N.Y.) 1990;250(4984):1152-4.
1990: R Namikawa; K N Weilbaecher; H Kaneshima; E J Yee; Joseph M McCune
Long-term human hematopoiesis in the SCID-hu mouse.
The Journal of experimental medicine 1990;172(4):1055-63.
1990: Joseph M McCune; R Namikawa; C C Shih; L Rabin; H Kaneshima
Suppression of HIV infection in AZT-treated SCID-hu mice.
Science (New York, N.Y.) 1990;247(4942):564-6.
1990: Joseph M McCune; H Kaneshima; L Rabin; C C Shih; R Namikawa
Preclinical evaluation of antiviral compounds in the SCID-hu mouse.
Annals of the New York Academy of Sciences 1990;616():281-6.
1989: Joseph M McCune; H Kaneshima; M Lieberman; I L Weissman; R Namikawa
The scid-hu mouse: current status and potential applications.
Current topics in microbiology and immunology 1989;152():183-93.
1988: R Namikawa; H Kaneshima; M Lieberman; Irving L Weissman; Joseph M McCune
Infection of the SCID-hu mouse by HIV-1.
Science (New York, N.Y.) 1988;242(4886):1684-6.
1988: Joseph M McCune; R Namikawa; H Kaneshima; L D Shultz; M Lieberman; Irving L Weissman
The SCID-hu mouse: murine model for the analysis of human hematolymphoid differentiation and function.
Science (New York, N.Y.) 1988;241(4873):1632-9.
1988: Joseph M McCune; L B Rabin; Mark B Feinberg; M Lieberman; J C Kosek; G R Reyes; Irving L Weissman
Endoproteolytic cleavage of gp160 is required for the activation of human immunodeficiency virus.
Cell 1988;53(1):55-67.
1987: M Lieberman; G A Hansteen; Joseph M McCune; M L Scott; J H White; Irving L Weissman
Indirect induction of radiation lymphomas in mice. Evidence for a novel, transmissible leukemogen.
The Journal of experimental medicine 1987;166(6):1883-93.
1981: Joseph M McCune; S M Fu
Ig biosynthesis in a human pre-B cell line.
Journal of immunology (Baltimore, Md. : 1950) 1981;127(6):2609-11.
1981: Joseph M McCune; S M Fu; H G Kunkel; Günter Blobel
Biogenesis of membrane-bound and secreted immunoglobulins: two primary translation products of the human delta chain, differentially N-glycosylated to four discrete forms in vivo and in vitro.
Proceedings of the National Academy of Sciences of the United States of America 1981;78(8):5127-31.
1981: Joseph M McCune; S M Fu; H G Kunkel
J chain biosynthesis in pre-B cells and other possible precursor B cells.
The Journal of experimental medicine 1981;154(1):138-45.
1981: Joseph M McCune; S M Fu; Günter Blobel; H G Kunkel
Biogenesis of membrane-bound and secreted immunoglobulins. II. Two forms of the human alpha chain translated in vitro and processed in vivo as distinct polypeptide chains.
The Journal of experimental medicine 1981;153(6):1684-9.
1980: S M Fu; J N Hurley; Joseph M McCune; H G Kunkel; R A Good
Pre-B cells and other possible precursor lymphoid cell lines derived from patients with X-linked agammaglobulinemia.
The Journal of experimental medicine 1980;152(6):1519-26.
1980: D T Yu; Joseph M McCune; S M Fu; R J Winchester; H G Kunkel
Two types of Ia-positive T cells. Synthesis and exchange of Ia antigens.
The Journal of experimental medicine 1980;152(2 Pt 2):89s-98s.
1980: Joseph M McCune; V R Lingappa; S M Fu; Günter Blobel; H G Kunkel
Biogenesis of membrane-bound and secreted immunoglobulins. I. Two distinct translation products of human mu-chain, with identical N-termini and different C-termini.
The Journal of experimental medicine 1980;152(2):463-8.
1976: R E Humphreys; Joseph M McCune; L Chess; H C Herrman; D J Malenka; Dean L Mann; P Parham; S F Schlossman; J L Strominger
Isolation and immunologic characterization of a human. B-lymphocyte-specific, cell surface antigen.
The Journal of experimental medicine 1976;144(1):98-112.
1976: J L Strominger; R E Humphreys; Joseph M McCune; P Parham; R Robb; T Springer; C Terhorst
The immunoglobulin-like structure of human histocompatibility antigens.
Federation proceedings 1976;35(5):1177-82.
1975: Joseph M McCune; R E Humphreys; R R Yocum; J L Strominger
Enhanced representation of HL-A antigens on human lymphocytes after mitogenesis induced by phytohemagglutinin or Epstein-Barr virus.
Proceedings of the National Academy of Sciences of the United States of America 1975;72(8):3206-9.