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Hugh McDevitt

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Li-Fen Lee; Chih-Jian Lih; Chao-Jen Huang; Thai Cao; Stanley N Cohen; Hugh McDevitt
Genomic expression profiling of TNF-alpha-treated BDC2.5 diabetogenic CD4+ T cells.
Rodolfo J. Chaparro; Yves Konigshofer; Georg F Beilhack; Judith A Shizuru; Hugh McDevitt; Yueh-hsiu Chien
Nonobese diabetic mice express aspects of both type 1 and type 2 diabetes.
Ivana Durinovic-Belló; Silke Rosinger; Jennifer A Olson; Mauro Congia; Regina C Ahmad; Mathias Rickert; Johannes Hampl; Hubert Kalbacher; Jan Wouter Drijfhout; Elizabeth D Mellins; Sascha Al Dahouk; Thomas Kamradt; Markus J Maeurer; Carol Nhan; Bart O Roep; Bernhard O Boehm; Constantin Polychronakos; Gerald Nepom; Wolfram Karges; Hugh McDevitt; Grete Sønderstrup
DRB1*0401-restricted human T cell clone specific for the major proinsulin73-90 epitope expresses a down-regulatory T helper 2 phenotype.

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2008: Li-Fen Lee; Chih-Jian Lih; Chao-Jen Huang; Thai Cao; Stanley N Cohen; Hugh McDevitt
Genomic expression profiling of TNF-alpha-treated BDC2.5 diabetogenic CD4+ T cells.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(29):10107-12.
2006: Rodolfo J. Chaparro; Yves Konigshofer; Georg F Beilhack; Judith A Shizuru; Hugh McDevitt; Yueh-hsiu Chien
Nonobese diabetic mice express aspects of both type 1 and type 2 diabetes.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(33):12475-80.
2006: Ivana Durinovic-Belló; Silke Rosinger; Jennifer A Olson; Mauro Congia; Regina C Ahmad; Mathias Rickert; Johannes Hampl; Hubert Kalbacher; Jan Wouter Drijfhout; Elizabeth D Mellins; Sascha Al Dahouk; Thomas Kamradt; Markus J Maeurer; Carol Nhan; Bart O Roep; Bernhard O Boehm; Constantin Polychronakos; Gerald Nepom; Wolfram Karges; Hugh McDevitt; Grete Sønderstrup
DRB1*0401-restricted human T cell clone specific for the major proinsulin73-90 epitope expresses a down-regulatory T helper 2 phenotype.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(31):11683-8.
2005: Hugh McDevitt
Characteristics of autoimmunity in type 1 diabetes and type 1.5 overlap with type 2 diabetes.
Diabetes 2005;54 Suppl 2():S4-10.
2005: Jung-Tung Hung; Jen-Hsiang Liao; Yu-Chung Lin; Hsiu-Ying Chang; Shu-Fen Wu; Tsung-Hsien Chang; John T Kung; Shie-Liang Hsieh; Hugh McDevitt; Huey-Kang Sytwu
Immunopathogenic role of TH1 cells in autoimmune diabetes: evidence from a T1 and T2 doubly transgenic non-obese diabetic mouse model.
Journal of autoimmunity 2005;25(3):181-92.
2005: Li-Fen Lee; Baohui Xu; Sara A Michie; Georg F Beilhack; Tibor Warganich; Shannon Turley; Hugh McDevitt
The role of TNF-alpha in the pathogenesis of type 1 diabetes in the nonobese diabetic mouse: analysis of dendritic cell maturation.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(44):15995-6000.
2005: Emma L Masteller; Matthew R Warner; Qizhi Tang; Kristin V Tarbell; Hugh McDevitt; Jeffrey A Bluestone
Expansion of functional endogenous antigen-specific CD4+CD25+ regulatory T cells from nonobese diabetic mice.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(5):3053-9.
2004: Erik A Ranheim; Kristin V Tarbell; Michelle Krogsgaard; Valérie Mallet-Designe; Luc Teyton; Hugh McDevitt; Irving L Weissman
Selection of aberrant class II restricted CD8+ T cells in NOD mice expressing a glutamic acid decarboxylase (GAD)65-specific T cell receptor transgene.
Autoimmunity 2004;37(8):555-67.
2004: Hugh McDevitt
Specific antigen vaccination to treat autoimmune disease.
Proceedings of the National Academy of Sciences of the United States of America 2004;101 Suppl 2():14627-30.
2004: Hugh McDevitt
Ir genes--forty years on.
Clinical and investigative medicine. Médecine clinique et experimentale 2004;27(5):237-9.
2004: Seon-Kyeong Kim; Kristin V Tarbell; Maija Sanna; Mary Vadeboncoeur; Tibor Warganich; Mark Lee; Mark Davis; Hugh McDevitt
Prevention of type I diabetes transfer by glutamic acid decarboxylase 65 peptide 206-220-specific T cells.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(39):14204-9.
2004: Hugh McDevitt; Allen Chinitz
Genetic control of the antibody responses: relationship between immune response and histocompatibility (H-2) type. 1969.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(3):1500-1.
2004: Qizhi Tang; Kammi J Henriksen; Mingying Bi; Erik B Finger; Gregory L Szot; Jianqin Ye; Emma L Masteller; Hugh McDevitt; Mark Bonyhadi; Jeffrey A Bluestone
In vitro-expanded antigen-specific regulatory T cells suppress autoimmune diabetes.
The Journal of experimental medicine 2004;199(11):1455-65.
2003: Hugh McDevitt
The T cell response to glutamic acid decarboxylase 65 in T cell receptor transgenic NOD mice.
Annals of the New York Academy of Sciences 2003;1005():75-81.
2003: Rosetta Pedotti; Maija Sanna; Mindy Tsai; Jason DeVoss; Lawrence Steinman; Hugh McDevitt; Stephen J Galli
Severe anaphylactic reactions to glutamic acid decarboxylase (GAD) self peptides in NOD mice that spontaneously develop autoimmune type 1 diabetes mellitus.
BMC immunology 2003;4():2.
2002: Ava J Wu; Hong Hua; Sibyl H Munson; Hugh McDevitt
Tumor necrosis factor-alpha regulation of CD4+CD25+ T cell levels in NOD mice.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(19):12287-92.
2002: Kristin V Tarbell; Mark Lee; Erik A Ranheim; Cheng Chi Chao; Maija Sanna; Seon-Kyeong Kim; Peter Dickie; Luc Teyton; Mark Davis; Hugh McDevitt
CD4(+) T cells from glutamic acid decarboxylase (GAD)65-specific T cell receptor transgenic mice are not diabetogenic and can delay diabetes transfer.
The Journal of experimental medicine 2002;196(4):481-92.
2002: Hugh McDevitt
The discovery of linkage between the MHC and genetic control of the immune response.
Immunological reviews 2002;185():78-85.
2002: Hugh McDevitt; Sibyl H Munson; Catherine Rachel Ettinger; Ava Wu
Multiple roles for tumor necrosis factor-alpha and lymphotoxin alpha/beta in immunity and autoimmunity.
Arthritis research 2002;4 Suppl 3():S141-52.
2001: Hugh McDevitt
Closing in on type 1 diabetes.
The New England journal of medicine 2001;345(14):1060-1.
2001: Catherine Rachel Ettinger; Sibyl H Munson; C C Chao; M Vadeboncoeur; J Toma; Hugh McDevitt
A critical role for lymphotoxin-beta receptor in the development of diabetes in nonobese diabetic mice.
The Journal of experimental medicine 2001;193(11):1333-40.
2001: Grete Sønderstrup; Hugh McDevitt
DR, DQ, and you: MHC alleles and autoimmunity.
The Journal of clinical investigation 2001;107(7):795-6.
2001: Hugh McDevitt
The role of MHC class II molecules in the pathogenesis and prevention of Type I diabetes.
Advances in experimental medicine and biology 2001;490():59-66.
2000: Hugh McDevitt
A new model for rheumatoid arthritis?
Arthritis research 2000;2(2):85-9.
1999: Grete Sønderstrup; Andrew P Cope; Salil Patel; Mauro Congia; N Hain; Frances C Hall; Sarah Louise Parry; Lars Fugger; Sara A Michie; Hugh McDevitt
HLA class II transgenic mice: models of the human CD4+ T-cell immune response.
Immunological reviews 1999;172():335-43.
1999: C C Chao; HK Sytwu; E L Chen; J Toma; Hugh McDevitt
The role of MHC class II molecules in susceptibility to type I diabetes: identification of peptide epitopes and characterization of the T cell repertoire.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(16):9299-304.
1999: CI Pearson; Anand Gautam; I C Rulifson; Roland S Liblau; Hugh McDevitt
A small number of residues in the class II molecule I-Au confer the ability to bind the myelin basic protein peptide Ac1-11.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(1):197-202.
1999: CI Pearson; Hugh McDevitt
Redirecting Th1 and Th2 responses in autoimmune disease.
Current topics in microbiology and immunology 1999;238():79-122.
1998: S M Singer; Roland Tisch; XD Yang; HK Sytwu; Roland S Liblau; Hugh McDevitt
Prevention of diabetes in NOD mice by a mutated I-Ab transgene.
Diabetes 1998;47(10):1570-7.
1998: Grete Sønderstrup; Hugh McDevitt
Identification of autoantigen epitopes in MHC class II transgenic mice.
Immunological reviews 1998;164():129-38.
1998: Catherine Rachel Ettinger; Reina E Mebius; J L Browning; Sara A Michie; S van Tuijl; Georg Kraal; W van Ewijk; Hugh McDevitt
Effects of tumor necrosis factor and lymphotoxin on peripheral lymphoid tissue development.
International immunology 1998;10(6):727-41.
1998: Roland Tisch; Roland S Liblau; XD Yang; P Liblau; Hugh McDevitt
Induction of GAD65-specific regulatory T-cells inhibits ongoing autoimmune diabetes in nonobese diabetic mice.
Diabetes 1998;47(6):894-9.
1997: Roland S Liblau; Roland Tisch; Nadège Bercovici; Hugh McDevitt
Systemic antigen in the treatment of T-cell-mediated autoimmune diseases.
Immunology today 1997;18(12):599-604.
1997: Diane Wherrett; S M Singer; Hugh McDevitt
Reduction in diabetes incidence in an I-Ag7 transgenic nonobese diabetic mouse line.
Diabetes 1997;46(12):1970-4.
1997: Balaji Balasa; Troy Krahl; G Patstone; Jongdae Lee; Roland Tisch; Hugh McDevitt; Nora Sarvetnick
CD40 ligand-CD40 interactions are necessary for the initiation of insulitis and diabetes in nonobese diabetic mice.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(9):4620-7.
1997: XD Yang; HK Sytwu; Hugh McDevitt; Sara A Michie
Involvement of beta 7 integrin and mucosal addressin cell adhesion molecule-1 (MAdCAM-1) in the development of diabetes in obese diabetic mice.
Diabetes 1997;46(10):1542-7.
1997: CI Pearson; D E Smilek; J S Danska; Hugh McDevitt
Induction of a heterogeneous TCR repertoire in (PL/JXSJL/J)F1 mice by myelin basic protein peptide Ac1-11 and its analog Ac1-11[4A].
Molecular immunology 1997;34(11):781-92.
1997: A Cope; Catherine Rachel Ettinger; Hugh McDevitt
The role of TNF alpha and related cytokines in the development and function of the autoreactive T-cell repertoire.
Research in immunology 1997;148(5):307-12.
1997: Andrew P Cope; Roland S Liblau; X D Yang; Mauro Congia; Carlo Laudanna; R D Schreiber; L Probert; george kollias; Hugh McDevitt
Chronic tumor necrosis factor alters T cell responses by attenuating T cell receptor signaling.
The Journal of experimental medicine 1997;185(9):1573-84.
1997: CI Pearson; W van Ewijk; Hugh McDevitt
Induction of apoptosis and T helper 2 (Th2) responses correlates with peptide affinity for the major histocompatibility complex in self-reactive T cell receptor transgenic mice.
The Journal of experimental medicine 1997;185(4):583-99.
1997: C C Chao; Hugh McDevitt
Identification of immunogenic epitopes of GAD 65 presented by Ag7 in non-obese diabetic mice.
Immunogenetics 1997;46(1):29-34.
1997: Z Fronek; M M Cheung; Hugh McDevitt
Association of DPB1 genes with systemic lupus erythematosus.
The Journal of rheumatology 1997;24(1):232-4.
1996: Catherine Rachel Ettinger; Jeffrey L Browning; Sara A Michie; W van Ewijk; Hugh McDevitt
Disrupted splenic architecture, but normal lymph node development in mice expressing a soluble lymphotoxin-beta receptor-IgG1 fusion protein.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(23):13102-7.
1996: HK Sytwu; Roland S Liblau; Hugh McDevitt
The roles of Fas/APO-1 (CD95) and TNF in antigen-induced programmed cell death in T cell receptor transgenic mice.
Immunity 1996;5(1):17-30.
1996: Hugh McDevitt; S Singer; Roland Tisch
The role of MHC class II genes in susceptibility and resistance to type I diabetes mellitus in the NOD mouse.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 1996;28(6):287-8.
1996: XD Yang; Sara A Michie; Reina E Mebius; Roland Tisch; I Weissman; Hugh McDevitt
The role of cell adhesion molecules in the development of IDDM: implications for pathogenesis and therapy.
Diabetes 1996;45(6):705-10.
1996: Roland Tisch; Hugh McDevitt
Insulin-dependent diabetes mellitus.
Cell 1996;85(3):291-7.
1996: Roland S Liblau; Roland Tisch; Kevan M Shokat; X Yang; N Dumont; Christopher C Goodnow; Hugh McDevitt
Intravenous injection of soluble antigen induces thymic and peripheral T-cells apoptosis.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(7):3031-6.
1996: S M Singer; D T Umetsu; Hugh McDevitt
High copy number I-Ab transgenes induce production of IgE through an interluekin 4-dependent mechanism.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(7):2947-52.
1996: Lars Fugger; J Liang; A Gautam; J B Rothbard; Hugh McDevitt
Quantitative analysis of peptides from myelin basic protein binding to the MHC class II protein, I-Au, which confers susceptibility to experimental allergic encephalomyelitis.
Molecular medicine (Cambridge, Mass.) 1996;2(2):181-8.
1995: M Vaysburd; C Lock; Hugh McDevitt
Prevention of insulin-dependent diabetes mellitus in nonobese diabetic mice by immunogenic but not by tolerated peptides.
The Journal of experimental medicine 1995;182(3):897-902.
1995: Hugh McDevitt
Autoimmune diabetes and its antigenic triggers.
Hospital practice (1995) 1995;30(7):55-62.
1995: Hugh McDevitt
Evolution of MHC class II allelic diversity.
Immunological reviews 1995;143():113-22.
1995: Roland S Liblau; S M Singer; Hugh McDevitt
Th1 and Th2 CD4+ T cells in the pathogenesis of organ-specific autoimmune diseases.
Immunology today 1995;16(1):34-8.
1995: XD Yang; Roland Tisch; Hugh McDevitt
Selective targets for immunotherapy in autoimmune disease.
Chemical immunology 1995;60():20-31.
1994: XD Yang; Sara A Michie; Roland Tisch; Nathan Karin; Lawrence Steinman; Hugh McDevitt
A predominant role of integrin alpha 4 in the spontaneous development of autoimmune diabetes in nonobese diabetic mice.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(26):12604-8.
1994: Roland Tisch; XD Yang; Roland S Liblau; Hugh McDevitt
Administering glutamic acid decarboxylase to NOD mice prevents diabetes.
Journal of autoimmunity 1994;7(6):845-50.
1994: Roland S Liblau; CI Pearson; Kevan M Shokat; Roland Tisch; XD Yang; Hugh McDevitt
High-dose soluble antigen: peripheral T-cell proliferation or apoptosis.
Immunological reviews 1994;142():193-208.
1994: XD Yang; Sara A Michie; Roland Tisch; Nathan Karin; Lawrence Steinman; Hugh McDevitt
Cell adhesion molecules: a selective therapeutic target for alleviation of IDDM.
Journal of autoimmunity 1994;7(6):859-64.
1994: PG Schlegel; Rina Aharoni; D E Smilek; L P Fernandez; Hugh McDevitt; N Tran; M Vaysburd; Nelson J Chao
Prevention of graft-versus-host disease by peptides binding to class II major histocompatibility complex molecules.
Blood 1994;84(8):2802-10.
1994: XD Yang; Roland Tisch; S M Singer; Z A Cao; Roland S Liblau; R D Schreiber; Hugh McDevitt
Effect of tumor necrosis factor alpha on insulin-dependent diabetes mellitus in NOD mice. I. The early development of autoimmunity and the diabetogenic process.
The Journal of experimental medicine 1994;180(3):995-1004.
1994: Roland Tisch; XD Yang; Hugh McDevitt
Therapeutic intervention in autoimmunity.
Behring Institute Mitteilungen 1994;(94):171-8.
1994: Roland Tisch; Hugh McDevitt
Antigen-specific immunotherapy: is it a real possibility to combat T-cell-mediated autoimmunity?
Proceedings of the National Academy of Sciences of the United States of America 1994;91(2):437-8.
1994: Anand Gautam; C B Lock; D E Smilek; CI Pearson; Lawrence Steinman; Hugh McDevitt
Minimum structural requirements for peptide presentation by major histocompatibility complex class II molecules: implications in induction of autoimmunity.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(2):767-71.
1994: SD Patel; J J Monaco; Hugh McDevitt
Delineation of the subunit composition of human proteasomes using antisera against the major histocompatibility complex-encoded LMP2 and LMP7 subunits.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(1):296-300.
1994: C Gelber; L Paborsky; S Singer; D McAteer; Roland Tisch; C Jolicoeur; R Buelow; Hugh McDevitt; C Garrison Fathman
Isolation of nonobese diabetic mouse T-cells that recognize novel autoantigens involved in the early events of diabetes.
Diabetes 1994;43(1):33-9.
1994: P M van Endert; Roland S Liblau; SD Patel; Lars Fugger; T Lopez; Flemming Pociot; J Nerup; Hugh McDevitt
Major histocompatibility complex-encoded antigen processing gene polymorphism in IDDM.
Diabetes 1994;43(1):110-7.
1993: XD Yang; Nathan Karin; Roland Tisch; Lawrence Steinman; Hugh McDevitt
Inhibition of insulitis and prevention of diabetes in nonobese diabetic mice by blocking L-selectin and very late antigen 4 adhesion receptors.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(22):10494-8.
1993: Roland Tisch; XD Yang; S M Singer; Roland S Liblau; Lars Fugger; Hugh McDevitt
Immune response to glutamic acid decarboxylase correlates with insulitis in non-obese diabetic mice.
Nature 1993;366(6450):72-5.
1993: S M Singer; Roland Tisch; XD Yang; Hugh McDevitt
An Abd transgene prevents diabetes in nonobese diabetic mice by inducing regulatory T cells.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(20):9566-70.
1993: Roland S Liblau; P M van Endert; M Sandberg-Wollheim; SD Patel; M T Lopez; S Land; Lars Fugger; Hugh McDevitt
Antigen processing gene polymorphisms in HLA-DR2 multiple sclerosis.
Neurology 1993;43(6):1192-7.
1992: P M van Endert; M T Lopez; SD Patel; J J Monaco; Hugh McDevitt
Genomic polymorphism, recombination, and linkage disequilibrium in human major histocompatibility complex-encoded antigen-processing genes.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(23):11594-7.
1992: Anand Gautam; CI Pearson; D E Smilek; Lawrence Steinman; Hugh McDevitt
A polyalanine peptide with only five native myelin basic protein residues induces autoimmune encephalomyelitis.
The Journal of experimental medicine 1992;176(2):605-9.
1992: A S Lundberg; Hugh McDevitt
Evolution of major histocompatibility complex class II allelic diversity: direct descent in mice and humans.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(14):6545-9.
1992: Anand Gautam; CI Pearson; Animesh Sinha; D E Smilek; Lawrence Steinman; Hugh McDevitt
Inhibition of experimental autoimmune encephalomyelitis by a nonimmunogenic non-self peptide that binds to I-Au.
Journal of immunology (Baltimore, Md. : 1950) 1992;148(10):3049-54.
1992: C O Jacob; S Aiso; R D Schreiber; Hugh McDevitt
Monoclonal anti-tumor necrosis factor antibody renders non-obese diabetic mice hypersensitive to irradiation and enhances insulitis development.
International immunology 1992;4(5):611-4.
1992: D E Smilek; Anand Gautam; C Pearson; Lawrence Steinman; Hugh McDevitt
EAE: a model for immune intervention with synthetic peptides.
International reviews of immunology 1992;9(3):223-30.
1991: S Gilfillan; S Aiso; D Smilek; D L Woodland; E Palmer; Hugh McDevitt
An immune response defect due to low levels of class II cell surface expression. Analysis of antigen presentation and positive selection.
Journal of immunology (Baltimore, Md. : 1950) 1991;147(12):4074-81.
1991: D E Smilek; David C Wraith; S Hodgkinson; S Dwivedy; Lawrence Steinman; Hugh McDevitt
A single amino acid change in a myelin basic protein peptide confers the capacity to prevent rather than induce experimental autoimmune encephalomyelitis.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(21):9633-7.
1991: C Lock; D Smilek; A Gautam; M Vaysburd; S Dwivedy; Hugh McDevitt
Competitive inhibition of antigen presentation in animal models of autoimmune disease.
Seminars in immunology 1991;3(4):247-55.
1991: Hugh McDevitt
Ir genes: towards the year 2000.
Research in immunology 1991;142(5-6):509-13.
1991: Animesh Sinha; R B Bell; Lawrence Steinman; Hugh McDevitt
Oligonucleotide dot-blot analysis of HLA-DQ beta alleles associated with multiple sclerosis.
Journal of neuroimmunology 1991;32(1):61-5.
1991: Z Fronek; Luika Timmerman; Hugh McDevitt
A rare HLA DQB allele sequenced from patients with systemic lupus erythematosus.
Human immunology 1991;30(2):77-84.
1991: C O Jacob; G D Lewis; Hugh McDevitt
MHC class II-associated variation in the production of tumor necrosis factor in mice and humans: relevance to the pathogenesis of autoimmune diseases.
Immunologic research 1991;10(2):156-68.
1990: D E Smilek; C B Lock; Hugh McDevitt
Antigen recognition and peptide-mediated immunotherapy in autoimmune disease.
Immunological reviews 1990;118():37-71.
1990: Z Fronek; Luika Timmerman; C A Alper; Bevra H Hahn; Kenneth C Kalunian; B Matija Peterlin; Hugh McDevitt
Major histocompatibility complex genes and susceptibility to systemic lupus erythematosus.
Arthritis and rheumatism 1990;33(10):1542-53.
1990: S Gilfillan; S Aiso; Sara A Michie; Hugh McDevitt
Immune deficiency due to high copy numbers of an Ak beta transgene.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(18):7319-23.
1990: S Gilfillan; S Aiso; Sara A Michie; Hugh McDevitt
The effect of excess beta-chain synthesis on cell-surface expression of allele-mismatched class II heterodimers in vivo.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(18):7314-8.
1990: Bevra H Hahn; Kenneth C Kalunian; Z Fronek; N Panosian-Sahakian; J S Louie; Hugh McDevitt; Fanny M Ebling
Idiotypic characteristics of immunoglobulins associated with human systemic lupus erythematosus. Association of high serum levels of IdGN2 with nephritis but not with HLA class II genes predisposing to nephritis.
Arthritis and rheumatism 1990;33(7):978-84.
1990: Animesh Sinha; M T Lopez; Hugh McDevitt
Autoimmune diseases: the failure of self tolerance.
Science (New York, N.Y.) 1990;248(4961):1380-8.
1990: C O Jacob; S Aiso; Sara A Michie; Hugh McDevitt; H Acha-Orbea
Prevention of diabetes in nonobese diabetic mice by tumor necrosis factor (TNF): similarities between TNF-alpha and interleukin 1.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(3):968-72.
1990: C O Jacob; Z Fronek; G D Lewis; M Koo; J A Hansen; Hugh McDevitt
Heritable major histocompatibility complex class II-associated differences in production of tumor necrosis factor alpha: relevance to genetic predisposition to systemic lupus erythematosus.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(3):1233-7.
1990: Jayne S Danska; B W McIntyre; Hugh McDevitt; Irving L Weissman
Structural similarity between a primitive chordate membrane heterodimer and lymphocyte antigen receptors.
International immunology 1990;2(9):795-802.
1990: H Acha-Orbea; Hugh McDevitt
The role of class II molecules in development of insulin-dependent diabetes mellitus in mice, rats and humans.
Current topics in microbiology and immunology 1990;156():103-19.
1990: David C Wraith; D E Smilek; Dennis J Mitchell; Lawrence Steinman; Hugh McDevitt
T cell recognition in experimental autoimmune encephalomyelitis: prospects for immune intervention with synthetic peptides.
International reviews of immunology 1990;6(1):37-47.
1989: David C Wraith; D E Smilek; Dennis J Mitchell; Lawrence Steinman; Hugh McDevitt
Antigen recognition in autoimmune encephalomyelitis and the potential for peptide-mediated immunotherapy.
Cell 1989;59(2):247-55.
1989: C B Davis; Dennis J Mitchell; David C Wraith; J A Todd; Scott S Zamvil; Hugh McDevitt; Lawrence Steinman; Patricia P Jones
Polymorphic residues on the I-A beta chain modulate the stimulation of T cell clones specific for the N-terminal peptide of the autoantigen myelin basic protein.
Journal of immunology (Baltimore, Md. : 1950) 1989;143(7):2083-93.
1989: David C Wraith; Hugh McDevitt; Lawrence Steinman; H Acha-Orbea
T cell recognition as the target for immune intervention in autoimmune disease.
Cell 1989;57(5):709-15.
1989: C B Davis; J M Buerstedde; David J McKean; Patricia P Jones; Hugh McDevitt; David C Wraith
The role of polymorphic I-Ak beta chain residues in presentation of a peptide from myelin basic protein.
The Journal of experimental medicine 1989;169(6):2239-44.
1989: C O Jacob; Joseph Holoshitz; P Van der Meide; Samuel Strober; Hugh McDevitt
Heterogeneous effects of IFN-gamma in adjuvant arthritis.
Journal of immunology (Baltimore, Md. : 1950) 1989;142(5):1500-5.
1989: N J Chao; Luika Timmerman; Hugh McDevitt; C O Jacob
Molecular characterization of MHC class II antigens (beta 1 domain) in the BB diabetes-prone and -resistant rat.
Immunogenetics 1989;29(4):231-4.
1989: Hugh McDevitt; David C Wraith; D E Smilek; A S Lundberg; Lawrence Steinman
Evolution, function, and utilization of major histocompatibility complex polymorphism in autoimmune disease.
Cold Spring Harbor symposia on quantitative biology 1989;54 Pt 2():853-7.
1989: H Acha-Orbea; Lawrence Steinman; Hugh McDevitt
T cell receptors in murine autoimmune diseases.
Annual review of immunology 1989;7():371-405.
1989: M Motoyama; Thomas Kilduff; B S Lee; William C Dement; Hugh McDevitt
Restriction fragment length polymorphism in canine narcolepsy.
Immunogenetics 1989;29(2):124-6.
1989: H Acha-Orbea; Lawrence Steinman; Hugh McDevitt
T cell receptors in autoimmune disease as targets for immune intervention.
Genome / National Research Council Canada = Génome / Conseil national de recherches Canada 1989;31(2):656-61.
1988: Z Fronek; Luika Timmerman; C A Alper; Bevra H Hahn; Kenneth C Kalunian; B Matija Peterlin; Hugh McDevitt
Major histocompatibility complex associations with systemic lupus erythematosus.
The American journal of medicine 1988;85(6A):42-4.
1988: K Sakai; Animesh Sinha; Dennis J Mitchell; Scott S Zamvil; J B Rothbard; Hugh McDevitt; Lawrence Steinman
Involvement of distinct murine T-cell receptors in the autoimmune encephalitogenic response to nested epitopes of myelin basic protein.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(22):8608-12.
1988: N E Adelman; D Watling; Hugh McDevitt
In vivo effects of antibodies to immune response gene products. II. Suppression of humoral immune responses with monoclonal anti-I-A is due to suppressor cells.
International reviews of immunology 1988;3(4):333-44.
1988: H Acha-Orbea; Dennis J Mitchell; L Timmermann; David C Wraith; G S Tausch; M K Waldor; Scott S Zamvil; Hugh McDevitt; Lawrence Steinman
Limited heterogeneity of T cell receptors from lymphocytes mediating autoimmune encephalomyelitis allows specific immune intervention.
Cell 1988;54(2):263-73.
1988: Scott S Zamvil; Dennis J Mitchell; N E Lee; A C Moore; M K Waldor; K Sakai; J B Rothbard; Hugh McDevitt; Lawrence Steinman; H Acha-Orbea
Predominant expression of a T cell receptor V beta gene subfamily in autoimmune encephalomyelitis.
The Journal of experimental medicine 1988;167(5):1586-96.
1988: Animesh Sinha; Chaim Brautbar; F Szafer; A Friedmann; E Tzfoni; J A Todd; Lawrence Steinman; Hugh McDevitt
A newly characterized HLA DQ beta allele associated with pemphigus vulgaris.
Science (New York, N.Y.) 1988;239(4843):1026-9.
1988: C O Jacob; Hugh McDevitt
Tumour necrosis factor-alpha in murine autoimmune 'lupus' nephritis.
Nature 1988;331(6154):356-8.
1987: J A Todd; J I Bell; Hugh McDevitt
HLA-DQ beta gene contributes to susceptibility and resistance to insulin-dependent diabetes mellitus.
Nature 1987;329(6140):599-604.
1987: J I Bell; Lawrence Steinman; K Toyka; Hugh McDevitt
HLA-DQ restriction fragment length polymorphisms in myasthenia gravis.
Annals of the New York Academy of Sciences 1987;505():382-7.
1987: J D Holloman; J I Bell; Thomas Kilduff; William C Dement; Christian Guilleminault; Hugh McDevitt
HLA-DR restriction-fragment-length polymorphisms in narcolepsy.
Journal of neuroscience research 1987;18(1):239-44.
1986: Lawrence Steinman; M K Waldor; Scott S Zamvil; M Lim; Leonore A Herzenberg; L Herzenberg; Hugh McDevitt; D Mitchell; Subramaniam Sriram
Therapy of autoimmune diseases with antibody to immune response gene products or to T-cell surface markers.
Annals of the New York Academy of Sciences 1986;475():274-84.
1983: M K Waldor; Subramaniam Sriram; Hugh McDevitt; Lawrence Steinman
In vivo therapy with monoclonal anti-I-A antibody suppresses immune responses to acetylcholine receptor.
Proceedings of the National Academy of Sciences of the United States of America 1983;80(9):2713-7.
1982: L Steinman; Subramaniam Sriram; N E Adelman; Scott S Zamvil; Hugh McDevitt; H Urich
Murine model for pertussis vaccine encephalopathy: linkage to H-2.
Nature 1982;299(5885):738-40.