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Jay McDonald

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TOP 3
Qi Yan; Tong Zhou; Jay M McDonald; Yuhua Song
Structural insight for the roles of fas death domain binding to FADD and oligomerization degree of the Fas-FADD complex in the death-inducing signaling complex formation: a computational study.
Di Pan; Yabing Chen; Jay M McDonald; Qi Yan; Yuhua Song
Trifluoperazine regulation of calmodulin binding to Fas: a computational study.
Gu Jing; Kaiyu Yuan; Amy N Turk; Nirag C Jhala; J Pablo Arnoletti; Kui Zhang; Jay M McDonald; Yabing Chen
Tamoxifen enhances therapeutic effects of gemcitabine on cholangiocarcinoma tumorigenesis.

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All Publications

2013: Qi Yan; Tong Zhou; Jay M McDonald; Yuhua Song
Structural insight for the roles of fas death domain binding to FADD and oligomerization degree of the Fas-FADD complex in the death-inducing signaling complex formation: a computational study.
Proteins 2013;81(3):377-85.
2011: Di Pan; Yabing Chen; Jay M McDonald; Qi Yan; Yuhua Song
Trifluoperazine regulation of calmodulin binding to Fas: a computational study.
Proteins 2011;79(8):2543-56.
2011: Gu Jing; Kaiyu Yuan; Amy N Turk; Nirag C Jhala; J Pablo Arnoletti; Kui Zhang; Jay M McDonald; Yabing Chen
Tamoxifen enhances therapeutic effects of gemcitabine on cholangiocarcinoma tumorigenesis.
Laboratory investigation; a journal of technical methods and pathology 2011;91(6):896-904.
2011: Xu Feng; Jay M McDonald
Disorders of bone remodeling.
Annual review of pathology 2011;6():121-45.
2009: Chang Hyun Byon; Robert W Hardy; Changchun Ren; Selvarangan Ponnazhagan; Danny R Welch; Jay M McDonald; Yabing Chen
Free fatty acids enhance breast cancer cell migration through plasminogen activator inhibitor-1 and SMAD4.
Laboratory investigation; a journal of technical methods and pathology 2009;89(11):1221-8.
2009: Pritish Pawar; Liping Ma; Chang Hyun Byon; Hui Liu; Eun-Young Ahn; Nirag C Jhala; J Pablo Arnoletti; Jay M McDonald; Yabing Chen
Molecular mechanisms of tamoxifen therapy for cholangiocarcinoma: role of calmodulin.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(4):1288-96.
2009: Olga A Mamaeva; Junghyun Kim; Gong Feng; Jay M McDonald
Calcium/calmodulin-dependent kinase II regulates notch-1 signaling in prostate cancer cells.
Journal of cellular biochemistry 2009;106(1):25-32.
2008: Yabing Chen; Xiaohong Wang; Lie Di; Guoping Fu; Yuhong Chen; Li Bai; Jianzhong Liu; Xu Feng; Jay M McDonald; Sue Michalek; Yinghong He; Mei Yu; Yang-Xin Fu; Renren Wen; Hui Wu; Demin Wang
Phospholipase Cgamma2 mediates RANKL-stimulated lymph node organogenesis and osteoclastogenesis.
The Journal of biological chemistry 2008;283(43):29593-601.
2008: Pritish S Pawar; Keith J Micoli; Haitao Ding; William J Cook; John C Kappes; Yabing Chen; Jay M McDonald
Calmodulin binding to cellular FLICE-like inhibitory protein modulates Fas-induced signalling.
The Biochemical journal 2008;412(3):459-68.
2008: Chang Hyun Byon; Amjad Javed; Qun Dai; John C Kappes; Thomas Landes Clemens; Victor Darley-Usmar; Jay M McDonald; Yabing Chen
Oxidative stress induces vascular calcification through modulation of the osteogenic transcription factor Runx2 by AKT signaling.
The Journal of biological chemistry 2008;283(22):15319-27.
2008: S W Simon Sham; Jay M McDonald; Keith J Micoli; N Rama Krishna
Solution structure of a calmodulin-binding domain in the carboxy-terminal region of HIV type 1 gp160.
AIDS research and human retroviruses 2008;24(4):607-16.
2008: Yabing Chen; Pritish Pawar; George Pan; Liping Ma; Hui Liu; Jay M McDonald
Calmodulin binding to the Fas-mediated death-inducing signaling complex in cholangiocarcinoma cells.
Journal of cellular biochemistry 2008;103(3):788-99.
2007: Hyeonju Yeo; Lauren H Beck; Sunnie R Thompson; Mary C Farach-Carson; Jay M McDonald; Thomas Landes Clemens; Majd zayzafoon
Conditional disruption of calcineurin B1 in osteoblasts increases bone formation and reduces bone resorption.
The Journal of biological chemistry 2007;282(48):35318-27.
2007: Ritu Saxena; George Pan; Jay M McDonald
Osteoblast and osteoclast differentiation in modeled microgravity.
Annals of the New York Academy of Sciences 2007;1116():494-8.
2007: George Pan; Eun-Young Ahn; Yabing Chen; Gong Feng; Vishnu Reddy; Nirag C Jhala; Jay M McDonald
Reciprocal co-expression of Fas and Fas ligand in human cholangiocarcinoma.
International journal of oncology 2007;31(4):843-50.
2007: Hyeonju Yeo; Lauren H Beck; Jay M McDonald; Majd zayzafoon
Cyclosporin A elicits dose-dependent biphasic effects on osteoblast differentiation and bone formation.
Bone 2007;40(6):1502-16.
2006: George Pan; Michael Kilby; Jay M McDonald
Modulation of osteoclastogenesis induced by nucleoside reverse transcriptase inhibitors.
AIDS research and human retroviruses 2006;22(11):1131-41.
2006: Yabing Chen; Jianmin Xu; Nirag C Jhala; Pritish Pawar; Zeng B Zhu; Liping Ma; Chang-Hyun Byon; Jay M McDonald
Fas-mediated apoptosis in cholangiocarcinoma cells is enhanced by 3,3'-diindolylmethane through inhibition of AKT signaling and FLICE-like inhibitory protein.
The American journal of pathology 2006;169(5):1833-42.
2006: Zeng B Zhu; Yabing Chen; Sharmila K Makhija; Baogen Lu; Minghui Wang; Angel A Rivera; Masato Yamamoto; shuyi wang; Gene P Siegal; David T Curiel; Jay M McDonald
Survivin promoter-based conditionally replicative adenoviruses target cholangiocarcinoma.
International journal of oncology 2006;29(5):1319-29.
2006: Hyeonju Yeo; Jay M McDonald; Majd zayzafoon
NFATc1: a novel anabolic therapeutic target for osteoporosis.
Annals of the New York Academy of Sciences 2006;1068():564-7.
2006: George Pan; Zhen Yang; Scott W Ballinger; Jay M McDonald
Pathogenesis of osteopenia/osteoporosis induced by highly active anti-retroviral therapy for AIDS.
Annals of the New York Academy of Sciences 2006;1068():297-308.
2006: Keith J Micoli; Olga Mamaeva; Sabine C Piller; Jennifer L Barker; George Pan; Eric Hunter; Jay M McDonald
Point mutations in the C-terminus of HIV-1 gp160 reduce apoptosis and calmodulin binding without affecting viral replication.
Virology 2006;344(2):468-79.
2006: Eric C Seales; Keith J Micoli; Jay M McDonald
Calmodulin is a critical regulator of osteoclastic differentiation, function, and survival.
Journal of cellular biochemistry 2006;97(1):45-55.
2005: Majd zayzafoon; Valerie E Meyers; Jay M McDonald
Microgravity: the immune response and bone.
Immunological reviews 2005;208():267-80.
2005: Valerie E Meyers; Majd zayzafoon; Joanne T Douglas; Jay M McDonald
RhoA and cytoskeletal disruption mediate reduced osteoblastogenesis and enhanced adipogenesis of human mesenchymal stem cells in modeled microgravity.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2005;20(10):1858-66.
2005: Xiaojun Wu; Eun-Young Ahn; Margaret A McKenna; Hyeonju Yeo; Jay M McDonald
Fas binding to calmodulin regulates apoptosis in osteoclasts.
The Journal of biological chemistry 2005;280(33):29964-70.
2005: Nirag C Jhala; Selwyn M Vickers; Pedram Argani; Jay M McDonald
Regulators of apoptosis in cholangiocarcinoma.
Archives of pathology & laboratory medicine 2005;129(4):481-6.
2005: Majd zayzafoon; Keertik Fulzele; Jay M McDonald
Calmodulin and calmodulin-dependent kinase IIalpha regulate osteoblast differentiation by controlling c-fos expression.
The Journal of biological chemistry 2005;280(8):7049-59.
2005: Liang Zhang; Margaret A McKenna; Nasser Said-Al-Naief; Xiaojun Wu; Xu Feng; Jay M McDonald
Osteoclastogenesis: the role of calcium and calmodulin.
Critical reviews in eukaryotic gene expression 2005;15(1):1-13.
2005: Xiaojun Wu; George Pan; Margaret A McKenna; Majd zayzafoon; Wencheng Xiong; Jay M McDonald
RANKL regulates Fas expression and Fas-mediated apoptosis in osteoclasts.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2005;20(1):107-16.
2004: Valerie E Meyers; Majd zayzafoon; Steve R Gonda; William E Gathings; Jay M McDonald
Modeled microgravity disrupts collagen I/integrin signaling during osteoblastic differentiation of human mesenchymal stem cells.
Journal of cellular biochemistry 2004;93(4):697-707.
2004: George Pan; Xiaojun Wu; Margaret A McKenna; Xu Feng; Tim Nagy; Jay M McDonald
AZT enhances osteoclastogenesis and bone loss.
AIDS research and human retroviruses 2004;20(6):608-20.
2004: Majd zayzafoon; William E Gathings; Jay M McDonald
Modeled microgravity inhibits osteogenic differentiation of human mesenchymal stem cells and increases adipogenesis.
Endocrinology 2004;145(5):2421-32.
2004: Eun-Young Ahn; Ssang-Taek Lim; William J Cook; Jay M McDonald
Calmodulin binding to the Fas death domain. Regulation by Fas activation.
The Journal of biological chemistry 2004;279(7):5661-6.
2004: Majd zayzafoon; Sarki A Abdulkadir; Jay M McDonald
Notch signaling and ERK activation are important for the osteomimetic properties of prostate cancer bone metastatic cell lines.
The Journal of biological chemistry 2004;279(5):3662-70.
2003: Xiaojun Wu; Margaret A McKenna; Xu Feng; Tim Nagy; Jay M McDonald
Osteoclast apoptosis: the role of Fas in vivo and in vitro.
Endocrinology 2003;144(12):5545-55.
2003: Eun-Young Ahn; George Pan; Jae Hwan Oh; Ewan M Tytler; Jay M McDonald
The combination of calmodulin antagonists and interferon-gamma induces apoptosis through caspase-dependent and -independent pathways in cholangiocarcinoma cells.
The American journal of pathology 2003;163(5):2053-63.
2003: Liang Zhang; Xu Feng; Jay M McDonald
The role of calmodulin in the regulation of osteoclastogenesis.
Endocrinology 2003;144(10):4536-43.
2003: John P Williams; Allyn M Thames; Margaret A McKenna; Jay M McDonald
Differential effects of calmodulin and protein kinase C antagonists on bone resorption and acid transport activity.
Calcified tissue international 2003;73(3):290-6.
2003: John P Williams; Margaret A McKenna; Allyn M Thames; Jay M McDonald
Effects of cyclosporine on osteoclast activity: inhibition of calcineurin activity with minimal effects on bone resorption and acid transport activity.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2003;18(3):451-7.
2003: Qiang Wang; Yi Xie; Quansheng Du; Xiao-Jun Wu; Xu Feng; Lin Mei; Jay M McDonald; Wencheng Xiong
Regulation of the formation of osteoclastic actin rings by proline-rich tyrosine kinase 2 interacting with gelsolin.
The Journal of cell biology 2003;160(4):565-75.
2002: Eun-Young Ahn; George Pan; Selwyn M Vickers; Jay M McDonald
IFN-gammaupregulates apoptosis-related molecules and enhances Fas-mediated apoptosis in human cholangiocarcinoma.
International journal of cancer. Journal international du cancer 2002;100(4):445-51.
2002: Selwyn M Vickers; Nirag C Jhala; Eun-Young Ahn; Jay M McDonald; George Pan; Kirby I Bland
Tamoxifen (TMX)/Fas induced growth inhibition of human cholangiocarcinoma (HCC) by gamma interferon (IFN-gamma).
Annals of surgery 2002;235(6):872-8.
2001: Marina L Falany; Allyn M Thames; Jay M McDonald; HC Blair; Margaret A McKenna; R E Moore; Mary K Young; John P Williams
Osteoclasts secrete the chemotactic cytokine mim-1.
Biochemical and biophysical research communications 2001;281(1):180-5.
2000: Wilson Radding; J P Williams; Margaret A McKenna; R Tummala; Eric Hunter; Ewan M Tytler; Jay M McDonald
Calmodulin and HIV type 1: interactions with Gag and Gag products.
AIDS research and human retroviruses 2000;16(15):1519-25.
2000: Keith J Micoli; George Pan; Yalei Wu; John P Williams; William J Cook; Jay M McDonald
Requirement of calmodulin binding by HIV-1 gp160 for enhanced FAS-mediated apoptosis.
The Journal of biological chemistry 2000;275(2):1233-40.
2000: John P Williams; Margaret A McKenna; Allyn M Thames; Jay M McDonald
Tamoxifen inhibits phorbol ester stimulated osteoclastic bone resorption: an effect mediated by calmodulin.
Biochemistry and cell biology = Biochimie et biologie cellulaire 2000;78(6):715-23.
2000: Xing Ming Shi; HC Blair; xiangli yang; Jay M McDonald; Xu Cao
Tandem repeat of C/EBP binding sites mediates PPARgamma2 gene transcription in glucocorticoid-induced adipocyte differentiation.
Journal of cellular biochemistry 2000;76(3):518-27.
1999: C Bruce Alexander; Jay M McDonald
Cost-based (Part A) pathology physician services. Origin, current spectrum, and future.
Clinics in laboratory medicine 1999;19(4):783-96, vi.
1999: A Pickens; George Pan; Jay M McDonald; Selwyn M Vickers
Fas expression prevents cholangiocarcinoma tumor growth.
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 1999;3(4):374-81; discussion 382.
1999: George Pan; Selwyn M Vickers; A Pickens; JO Phillips; W Ying; John A Thompson; Gene P Siegal; Jay M McDonald
Apoptosis and tumorigenesis in human cholangiocarcinoma cells. Involvement of Fas/APO-1 (CD95) and calmodulin.
The American journal of pathology 1999;155(1):193-203.
1998: George Pan; T Zhou; Wilson Radding; M S Saag; J D Mountz; Jay M McDonald
Calmodulin antagonists inhibit apoptosis of CD4+ T-cells from patients with AIDS.
Immunopharmacology 1998;40(2):91-103.
1998: Jay M McDonald; SE Brossette; S A Moser
Pathology information systems: data mining leads to knowledge discovery.
Archives of pathology & laboratory medicine 1998;122(5):409-11.
1997: John P Williams; Jay M McDonald; Margaret A McKenna; SE Jordan; Wilson Radding; HC Blair
Differential effects of tamoxifen-like compounds on osteoclastic bone degradation, H(+)-ATPase activity, calmodulin-dependent cyclic nucleotide phosphodiesterase activity, and calmodulin binding.
Journal of cellular biochemistry 1997;66(3):358-69.
1997: John P Williams; HC Blair; Jay M McDonald; Margaret A McKenna; SE Jordan; Jodie Williford; Robert W Hardy
Regulation of osteoclastic bone resorption by glucose.
Biochemical and biophysical research communications 1997;235(3):646-51.
1997: Hanjoong Jo; Katalin Sipos; Young-Mi Go; R Law; J Rong; Jay M McDonald
Differential effect of shear stress on extracellular signal-regulated kinase and N-terminal Jun kinase in endothelial cells. Gi2- and Gbeta/gamma-dependent signaling pathways.
The Journal of biological chemistry 1997;272(2):1395-401.
1996: Z Pan; Wilson Radding; T Zhou; Eric Hunter; J Mountz; Jay M McDonald
Role of calmodulin in HIV-potentiated Fas-mediated apoptosis.
The American journal of pathology 1996;149(3):903-10.
1996: John P Williams; HC Blair; Margaret A McKenna; SE Jordan; Jay M McDonald
Regulation of avian osteoclastic H+ -ATPase and bone resorption by tamoxifen and calmodulin antagonists. Effects independent of steroid receptors.
The Journal of biological chemistry 1996;271(21):12488-95.
1996: MC Sekar; V Sambandam; W E Grizzle; Jay M McDonald
Dissociation of cyclic inositol phosphohydrolase activity from annexin III.
The Journal of biological chemistry 1996;271(14):8295-9.
1996: N S Wickramasinghe; Hanjoong Jo; Jay M McDonald; Robert W Hardy
Stearate inhibition of breast cancer cell proliferation. A mechanism involving epidermal growth factor receptor and G-proteins.
The American journal of pathology 1996;148(3):987-95.
1996: David B Sacks; Jay M McDonald
The pathogenesis of type II diabetes mellitus. A polygenic disease.
American journal of clinical pathology 1996;105(2):149-56.
1996: Wilson Radding; Z Q Pan; Eric Hunter; P Johnston; John P Williams; Jay M McDonald
Expression of HIV-1 envelope glycoprotein alters cellular calmodulin.
Biochemical and biophysical research communications 1996;218(1):192-7.
1995: John P Williams; Hanjoong Jo; R E Hunnicutt; D L Brautigan; Jay M McDonald
Tyrosine phosphorylation of phosphatase inhibitor 2.
Journal of cellular biochemistry 1995;57(3):415-22.
1995: Robert W Hardy; K B Gupta; Jay M McDonald; Jodie Williford; A Wells
Epidermal growth factor (EGF) receptor carboxy-terminal domains are required for EGF-induced glucose transport in transgenic 3T3-L1 adipocytes.
Endocrinology 1995;136(2):431-9.
1995: Raj K Singh; Robert W Hardy; M H Wang; Jodie Williford; Candece L Gladson; Jay M McDonald; G P Siegal
Stearate inhibits human tumor cell invasion.
Invasion & metastasis 1995;15(3-4):144-55.
1994: John P Williams; Hanjoong Jo; David B Sacks; D L Crimmins; R S Thoma; R E Hunnicutt; Wilson Radding; R K Sharma; Jay M McDonald
Tyrosine-phosphorylated calmodulin has reduced biological activity.
Archives of biochemistry and biophysics 1994;315(1):119-26.
1994: C Van Epps-Fung; John P Williams; Trudy L Cornwell; Thomas M Lincoln; Jay M McDonald; Wilson Radding; HC Blair
Regulation of osteoclastic acid secretion by cGMP-dependent protein kinase.
Biochemical and biophysical research communications 1994;204(2):565-71.
1994: Wilson Radding; John P Williams; Robert W Hardy; Jay M McDonald; C H Whitaker; E A Turbat-Herrera; HC Blair
Calmodulin concentrated at the osteoclast ruffled border modulates acid secretion.
Journal of cellular physiology 1994;160(1):17-28.
1994: J W Hunnicutt; Robert W Hardy; Jodie Williford; Jay M McDonald
Saturated fatty acid-induced insulin resistance in rat adipocytes.
Diabetes 1994;43(4):540-5.
1994: Robert W Hardy; Jay M McDonald; E E Remsen; D A d'Avignon; David B Sacks
The interaction of calmodulin and polylysine as studied by 1H NMR spectroscopy and sedimentation equilibrium centrifugation.
Biochemical and biophysical research communications 1994;198(1):309-17.
1993: Hanjoong Jo; S Byer; Jay M McDonald
Insulin stimulates association of a 41kDa G-protein (GIR41) with the insulin receptor.
Biochemical and biophysical research communications 1993;196(1):99-106.
1993: Hanjoong Jo; Wilson Radding; G M Anantharamaiah; Jay M McDonald
An insulin receptor peptide (1135-1156) stimulates guanosine 5'-[gamma-thio]triphosphate binding to the 67 kDa G-protein associated with the insulin receptor.
The Biochemical journal 1993;294 ( Pt 1)():19-24.
1993: MC Sekar; V Sambandam; Jay M McDonald
Bombesin and muscarinic receptor activation in rat pancreas generate cyclic inositol monophosphate: possible involvement of different phospholipase C isoenzymes.
Biochemical and biophysical research communications 1993;192(3):1079-85.
1992: Hanjoong Jo; B Y Cha; H W Davis; Jay M McDonald
Identification, partial purification, and characterization of two guanosine triphosphate-binding proteins associated with insulin receptors.
Endocrinology 1992;131(6):2855-62.
1992: David B Sacks; Jay M McDonald
Effects of cationic polypeptides on the activity, substrate interaction, and autophosphorylation of casein kinase II: a study with calmodulin.
Archives of biochemistry and biophysics 1992;299(2):275-80.
1992: David B Sacks; Harold W Davis; D L Crimmins; A Persechini; Jay M McDonald
Casein kinase II-catalysed phosphorylation of calmodulin is altered by amino acid deletions in the central helix of calmodulin.
Biochemical and biophysical research communications 1992;188(2):754-9.
1992: David B Sacks; Harold W Davis; D L Crimmins; Jay M McDonald
Insulin-stimulated phosphorylation of calmodulin.
The Biochemical journal 1992;286 ( Pt 1)():211-6.
1992: Robert W Hardy; J H Ladenson; Keith A Hruska; A H Jiwa; Jay M McDonald
The effects of extracellular calcium and epinephrine on cytosolic-free calcium in single rat adipocytes.
Endocrinology 1992;130(6):3694-702.
1992: David B Sacks; Harold W Davis; John P Williams; E L Sheehan; Joe G. N. Garcia; Jay M McDonald
Phosphorylation by casein kinase II alters the biological activity of calmodulin.
The Biochemical journal 1992;283 ( Pt 1)():21-4.
1990: H W Davis; Jay M McDonald
Modulation of guanine nucleotide effects on the insulin receptor by MgCl2.
Biochemical and biophysical research communications 1990;171(1):53-9.