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Timothy McDonnell
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27
Brisbay, Shawn
19
Medeiros, Jeffrey
15
Rassidakis, George
14
Meyn, Raymond
13
Roth, Jack
12
Spurgers, Kevin
12
Troncoso, Patricia
11
Logothetis, Christopher
10
Lai, Raymond
8
Bruckheimer, Elizabeth
8
Do, Kim-Anh
8
El-Naggar, Adel
7
Cabanillas, Fernando
7
Chari, Nikhil
7
Logothetis, Christopher
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All Publications
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2009: Chari Nikhil S; Pinaire Nicole L; Thorpe Lynnelle; Medeiros L Jeffrey; Routbort Mark J; McDonnell Timothy J
The p53 tumor suppressor network in cancer and the therapeutic modulation of cell death.
Apoptosis : an international journal on programmed cell death 2009;14(4):336-47.
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2009: Tsavachidou Dimitra; McDonnell Timothy J; Wen Sijin; Wang Xuemei; Vakar-Lopez Funda; Pisters Louis L; Pettaway Curtis A; Wood Christopher G; Do Kim-Anh; Thall Peter F; Stephens Clifton; Efstathiou Eleni; Taylor Robert; Menter David G; Troncoso Patricia; Lippman Scott M; Logothetis Christopher J; Kim Jeri
Selenium and vitamin E: cell type- and intervention-specific tissue effects in prostate cancer.
Journal of the National Cancer Institute 2009;101(5):306-20.
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2008: McDonnell Timothy J; Chari Nikhil S; Cho-Vega Jeong Hee; Troncoso Patricia; Wang Xuemei; Bueso-Ramos Carlos E; Coombes Kevin; Brisbay Shawn; Lopez Remigio; Prendergast George; Logothetis Christopher; Do Kim-Anh
Biomarker expression patterns that correlate with high grade features in treatment naive, organ-confined prostate cancer.
BMC medical genomics 2008;1():1.
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2007: Cho-Vega Jeong Hee; Tsavachidis Spiridon; Do Kim-Anh; Nakagawa Junichi; Medeiros L Jeffrey; McDonnell Timothy J
Dicarbonyl/L-xylulose reductase: a potential biomarker identified by laser-capture microdissection-micro serial analysis of gene expression of human prostate adenocarcinoma.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2007;16(12):2615-22.
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2007: Lee Sangjun; Chari Nikhil S; Kim Hyung Woo; Wang Xuemei; Roop Dennis R; Cho Song H; DiGiovanni John; McDonnell Timothy J
Cooperation of Ha-ras and Bcl-2 during multistep skin carcinogenesis.
Molecular carcinogenesis 2007;46(12):949-57.
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2007: Leroux M E; Auzenne E; Evans R; Hail N; Spohn W; Ghosh S C; Farquhar D; McDonnell T; Klostergaard J
Sphingolipids and the sphingosine kinase inhibitor, SKI II, induce BCL-2-independent apoptosis in human prostatic adenocarcinoma cells.
The Prostate 2007;67(15):1699-717.
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2007: Chari Nikhil S; McDonnell Timothy J
The sonic hedgehog signaling network in development and neoplasia.
Advances in anatomic pathology 2007;14(5):344-52.
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2007: Efstathiou Eleni; Troncoso Patricia; Wen Sijin; Do Kim-Anh; Pettaway Curtis A; Pisters Louis L; McDonnell Timothy J; Logothetis Christopher J
Initial modulation of the tumor microenvironment accounts for thalidomide activity in prostate cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(4):1224-31.
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2007: Han Xin; Garcia-Manero Guillermo; McDonnell Timothy J; Lozano Guillermina; Medeiros L Jeffrey; Xiao Lianchun; Rosner Gary; Nguyen Martin; Fernandez Michael; Valentin-Vega Yasmine A; Barboza Juan; Jones Daniel M; Rassidakis Georgios Z; Kantarjian Hagop M; Bueso-Ramos Carlos E
HDM4 (HDMX) is widely expressed in adult pre-B acute lymphoblastic leukemia and is a potential therapeutic target.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2007;20(1):54-62.
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2007: Wang Jing; Do Kim Anh; Wen Sijin; Tsavachidis Spyros; McDonnell Timothy J; Logothetis Christopher J; Coombes Kevin R
Merging microarray data, robust feature selection, and predicting prognosis in prostate cancer.
Cancer informatics 2007;2():87-97.
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2006: Khor Li-Yan; Desilvio Michelle; Li Rile; McDonnell Timothy J; Hammond M Elizabeth H; Sause William T; Pilepich Miljenko V; Okunieff Paul; Sandler Howard M; Pollack Alan
Bcl-2 and bax expression and prostate cancer outcome in men treated with radiotherapy in Radiation Therapy Oncology Group protocol 86-10.
International journal of radiation oncology, biology, physics 2006;66(1):25-30.
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2006: Spurgers Kevin B; Gold David L; Coombes Kevin R; Bohnenstiehl Nicole L; Mullins Brian; Meyn Raymond E; Logothetis Christopher J; McDonnell Timothy J
Identification of cell cycle regulatory genes as principal targets of p53-mediated transcriptional repression.
The Journal of biological chemistry 2006;281(35):25134-42.
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2006: Spurgers K B; Chari N S; Bohnenstiehl N L; McDonnell T J
Molecular mediators of cell death in multistep carcinogenesis: a path to targeted therapy.
Cell death and differentiation 2006;13(8):1360-70.
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2006: Broom B M; McDonnell T J; Subramanian D
Predicting altered pathways using extendable scaffolds.
International journal of bioinformatics research and applications 2006;2(1):3-18.
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2005: Kim Jeri; Sun Peiyu; Lam Ying-Wai; Troncoso Patricia; Sabichi Anita L; Babaian Richard J; Pisters Louis L; Pettaway Curtis A; Wood Christopher G; Lippman Scott M; McDonnell Timothy J; Lieberman Ronald; Logothetis Christopher; Ho Shuk-Mei
Changes in serum proteomic patterns by presurgical alpha-tocopherol and L-selenomethionine supplementation in prostate cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2005;14(7):1697-702.
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2005: Bueso-Ramos Carlos; Xu Yunling; McDonnell Timothy J; Brisbay Shawn; Pierce Sherry; Kantarjian Hagop; Rosner Gary; Garcia-Manero Guillermo
Protein expression of a triad of frequently methylated genes, p73, p57Kip2, and p15, has prognostic value in adult acute lymphocytic leukemia independently of its methylation status.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005;23(17):3932-9.
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2005: Cho-Vega Jeong Hee; Troncoso Patricia; Do Kim-Anh; Rago Carlo; Wang Xuemei; Tsavachidis Spiridon; Medeiros L Jeffrey; Spurgers Kevin; Logothetis Christopher; McDonnell Timothy J
Combined laser capture microdissection and serial analysis of gene expression from human tissue samples.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2005;18(4):577-84.
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2005: Bigelow Rebecca L H; Jen Emily Y; Delehedde Maryse; Chari Nikhil S; McDonnell Timothy J
Sonic hedgehog induces epidermal growth factor dependent matrix infiltration in HaCaT keratinocytes.
The Journal of investigative dermatology 2005;124(2):457-65.
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2004: Assikis Vasily J; Do Kim-Anh; Wen Sijin; Wang Xuemei; Cho-Vega Jeong Hee; Brisbay Shawn; Lopez Remigio; Logothetis Christopher J; Troncoso Patricia; Papandreou Christos N; McDonnell Timothy J
Clinical and biomarker correlates of androgen-independent, locally aggressive prostate cancer with limited metastatic potential.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(20):6770-8.
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2004: Cho-Vega Jeong Hee; Rassidakis George Z; Admirand Joan H; Oyarzo Mauricio; Ramalingam Preetha; Paraguya Aris; McDonnell Timothy J; Amin Hesham M; Medeiros L Jeffrey
MCL-1 expression in B-cell non-Hodgkin's lymphomas.
Human pathology 2004;35(9):1095-100.
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2004: Resetkova Erika; Gonzalez-Angulo Ana M; Sneige Nour; Mcdonnell Timothy J; Buzdar Aman U; Kau Shu Wan; Yamamura Yuko; Reuben James M; Hortobagyi Gabriel N; Cristofanilli Massimo
Prognostic value of P53, MDM-2, and MUC-1 for patients with inflammatory breast carcinoma.
Cancer 2004;101(5):913-7.
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2004: Amin Hesham M; McDonnell Timothy J; Ma Yupo; Lin Quan; Fujio Yasushi; Kunisada Keita; Leventaki Vasiliki; Das Pamela; Rassidakis George Z; Cutler Cathy; Medeiros L Jeffrey; Lai Raymond
Selective inhibition of STAT3 induces apoptosis and G(1) cell cycle arrest in ALK-positive anaplastic large cell lymphoma.
Oncogene 2004;23(32):5426-34.
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2004: Majumder Pradip K; Febbo Phillip G; Bikoff Rachel; Berger Raanan; Xue Qi; McMahon Louis M; Manola Judith; Brugarolas James; McDonnell Timothy J; Golub Todd R; Loda Massimo; Lane Heidi A; Sellers William R
mTOR inhibition reverses Akt-dependent prostate intraepithelial neoplasia through regulation of apoptotic and HIF-1-dependent pathways.
Nature medicine 2004;10(6):594-601.
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2004: Pisters Louis L; Pettaway Curtis A; Troncoso Patricia; McDonnell Timothy J; Stephens L Clifton; Wood Christopher G; Do Kim-Anh; Brisbay Shawn M; Wang Xuemei; Hossan Elizabeth A; Evans Robert B; Soto Cindy; Jacobson Marc G; Parker Karen; Merritt James A; Steiner Mitchell S; Logothetis Christopher J
Evidence that transfer of functional p53 protein results in increased apoptosis in prostate cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(8):2587-93.
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2004: Honda Tsuyoshi; Coppola Simona; Ghibelli Lina; Cho Song H; Kagawa Shunsuke; Spurgers Kevin B; Brisbay Shawn M; Roth Jack A; Meyn Raymond E; Fang Bingliang; McDonnell Timothy J
GSH depletion enhances adenoviral bax-induced apoptosis in lung cancer cells.
Cancer gene therapy 2004;11(4):249-55.
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2004: Rosser Charles J; Tanaka Motoyoshi; Pisters Louis L; Tanaka Noriyoshi; Levy Lawrence B; Hoover David C; Grossman H Barton; McDonnell Timothy J; Kuban Deborah A; Meyn Raymond E
Adenoviral-mediated PTEN transgene expression sensitizes Bcl-2-expressing prostate cancer cells to radiation.
Cancer gene therapy 2004;11(4):273-9.
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2004: Spurgers Kevin B; Coombes Kevin R; Meyn Raymond E; Gold David L; Logothetis Christopher J; Johnson Terry J; McDonnell Timothy J
A comprehensive assessment of p53-responsive genes following adenoviral-p53 gene transfer in Bcl-2-expressing prostate cancer cells.
Oncogene 2004;23(9):1712-23.
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2004: Nam Do-Hyun; Park Kwan; Park Chaehwa; Im Young-Hyuck; Kim Mi-Hyun; Lee Sangjun; Hong Seung-Chyul; Shin Hyung-Jin; Kim Jong-Hyun; Eoh Whan; McDonnell Timothy J
Intracranial inhibition of glioma cell growth by cyclooxygenase-2 inhibitor celecoxib.
Oncology reports 2004;11(2):263-8.
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2004: Drakos Elias; Rassidakis George Z; Lai Raymond; Herling Marco; O'Connor Sean L; Schmitt-Graeff Annette; McDonnell Timothy J; Medeiros L Jeffrey
Caspase-3 activation in systemic anaplastic large-cell lymphoma.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2004;17(1):109-16.
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2004: Bigelow Rebecca L H; Chari Nikhil S; Unden Anne Birgitte; Spurgers Kevin B; Lee Sangjun; Roop Dennis R; Toftgard Rune; McDonnell Timothy J
Transcriptional regulation of bcl-2 mediated by the sonic hedgehog signaling pathway through gli-1.
The Journal of biological chemistry 2004;279(2):1197-205.
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2003: Amin Hesham M; Medeiros L Jeffrey; Ma Yupo; Feretzaki Marianna; Das Pamela; Leventaki Vasiliki; Rassidakis George Z; O'Connor Sean L; McDonnell Timothy J; Lai Raymond
Inhibition of JAK3 induces apoptosis and decreases anaplastic lymphoma kinase activity in anaplastic large cell lymphoma.
Oncogene 2003;22(35):5399-407.
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2003: Tsao Anne S; McDonnell Timothy; Lam Stephen; Putnam Joe B; Bekele Nebiyou; Hong Waun Ki; Kurie Jonathan M
Increased phospho-AKT (Ser(473)) expression in bronchial dysplasia: implications for lung cancer prevention studies.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2003;12(7):660-4.
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2003: Rassidakis George Z; Jones Dan; Lai Raymond; Ramalingam Preetha; Sarris Andreas H; McDonnell Timothy J; Medeiros L Jeffrey
BCL-2 family proteins in peripheral T-cell lymphomas: correlation with tumour apoptosis and proliferation.
The Journal of pathology 2003;200(2):240-8.
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2003: Sah Nand K; Munshi Anupama; Kurland John F; McDonnell Timothy J; Su Bing; Meyn Raymond E
Translation inhibitors sensitize prostate cancer cells to apoptosis induced by tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) by activating c-Jun N-terminal kinase.
The Journal of biological chemistry 2003;278(23):20593-602.
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2003: Amin Hesham M; McDonnell Timothy J; Medeiros L Jeffrey; Rassidakis Georgios Z; Leventaki Vasiliki; O'Connor Sean L; Keating Michael J; Lai Raymond
Characterization of 4 mantle cell lymphoma cell lines.
Archives of pathology & laboratory medicine 2003;127(4):424-31.
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2003: Pollack Alan; Cowen Didier; Troncoso Patricia; Zagars Gunar K; von Eschenbach Andrew C; Meistrich Marvin L; McDonnell Timothy
Molecular markers of outcome after radiotherapy in patients with prostate carcinoma: Ki-67, bcl-2, bax, and bcl-x.
Cancer 2003;97(7):1630-8.
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2003: Aranha Olivia; Grignon Robert; Fernandes Neelesh; McDonnell Timothy J; Wood David P; Sarkar Fazlul H
Suppression of human prostate cancer cell growth by ciprofloxacin is associated with cell cycle arrest and apoptosis.
International journal of oncology 2003;22(4):787-94.
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2003: Bruckheimer Elizabeth M; Spurgers Kevin; Weigel Nancy L; Logothetis Christopher; McDonnell Timothy J
Regulation of Bcl-2 expression by dihydrotestosterone in hormone sensitive LNCaP-FGC prostate cancer cells.
The Journal of urology 2003;169(4):1553-7.
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2003: Rassidakis George Z; Claret Francois-Xavier; Lai Raymond; Zhang Qingxiu; Sarris Andreas H; McDonnell Timothy J; Medeiros L Jeffrey
Expression of p27(Kip1) and c-Jun activation binding protein 1 are inversely correlated in systemic anaplastic large cell lymphoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(3):1121-8.
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2003: Milas Ivan; Komaki Ritsuko; Hachiya Tsutomu; Bubb Robbin S; Ro Jae Y; Langford Lauren; Sawaya Raymond; Putnam Joe B; Allen Pamela; Cox James D; McDonnell Timothy J; Brock William; Hong Waun Ki; Roth Jack A; Milas Luka
Epidermal growth factor receptor, cyclooxygenase-2, and BAX expression in the primary non-small cell lung cancer and brain metastases.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(3):1070-6.
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2003: DuHadaway James B; Lynch Frank J; Brisbay Shawn; Bueso-Ramos Carlos; Troncoso Patricia; McDonnell Timothy; Prendergast George C
Immunohistochemical analysis of Bin1/Amphiphysin II in human tissues: diverse sites of nuclear expression and losses in prostate cancer.
Journal of cellular biochemistry 2003;88(3):635-42.
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2003: Swisher Stephen G; Roth Jack A; Komaki Ritsuko; Gu Jian; Lee J Jack; Hicks Marshall; Ro Jae Y; Hong Waun K; Merritt James A; Ahrar Kamaran; Atkinson N Edward; Correa Arlene M; Dolormente Marcelo; Dreiling Linda; El-Naggar Adel K; Fossella Frank; Francisco Rhodette; Glisson Bonnie; Grammer Susan; Herbst Roy; Huaringa Armando; Kemp Bonnie; Khuri Fadlo R; Kurie Jonathan M; Liao Zhongxio; McDonnell Timothy J; Morice Rudolfo; Morello Frank; Munden Reginald; Papadimitrakopoulou Vassiliki; Pisters Katherine M W; Putnam Joe B; Sarabia Arcenio J; Shelton Thomas; Stevens Craig; Shin Daniel M; Smythe William R; Vaporciyan Ara A; Walsh Garrett L; Yin Min
Induction of p53-regulated genes and tumor regression in lung cancer patients after intratumoral delivery of adenoviral p53 (INGN 201) and radiation therapy.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(1):93-101.
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2003: Khoury Joseph D; Medeiros L Jeffrey; Rassidakis George Z; McDonnell Timothy J; Abruzzo Lynne V; Lai Raymond
Expression of Mcl-1 in mantle cell lymphoma is associated with high-grade morphology, a high proliferative state, and p53 overexpression.
The Journal of pathology 2003;199(1):90-7.
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2003: Lai Raymond; Rassidakis George Z; Medeiros L Jeffrey; Leventaki Vasiliki; Keating Micheal; McDonnell Timothy J
Expression of STAT3 and its phosphorylated forms in mantle cell lymphoma cell lines and tumours.
The Journal of pathology 2003;199(1):84-9.
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2002: Rassidakis George Z; Medeiros L Jeffrey; Vassilakopoulos Theodoros P; Viviani Simonetta; Bonfante Valeria; Nadali Gianpaolo; Herling Marco; Angelopoulou Maria K; Giardini Roberto; Chilosi Marco; Kittas Christos; McDonnell Timothy J; Bonadonna Gianni; Gianni Alessandro M; Pizzolo Giovanni; Pangalis Gerassimos A; Cabanillas Fernando; Sarris Andreas H
BCL-2 expression in Hodgkin and Reed-Sternberg cells of classical Hodgkin disease predicts a poorer prognosis in patients treated with ABVD or equivalent regimens.
Blood 2002;100(12):3935-41.
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2002: Dong Qiang G; Sclabas Guido M; Fujioka Shuichi; Schmidt Christian; Peng Bailu; Wu TianAi; Tsao Ming-Sound; Evans Douglas B; Abbruzzese James L; McDonnell Timothy J; Chiao Paul J
The function of multiple IkappaB : NF-kappaB complexes in the resistance of cancer cells to Taxol-induced apoptosis.
Oncogene 2002;21(42):6510-9.
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2002: Rassidakis George Z; Jones Dan; Thomaides Athanasios; Sen Filiz; Lai Raymond; Cabanillas Fernando; McDonnell Timothy J; Medeiros L Jeffrey
Apoptotic rate in peripheral T-cell lymphomas. A study using a tissue microarray with validation on full tissue sections.
American journal of clinical pathology 2002;118(3):328-34.
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2002: Lai R; McDonnell T J; O'Connor S L; Medeiros L J; Oudat R; Keating M; Morgan M B; Curiel T J; Ford R J
Establishment and characterization of a new mantle cell lymphoma cell line, Mino.
Leukemia research 2002;26(9):849-55.
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2002: Cho Song; O'Connor Sean L; McDonnell Timothy J
Evidence that nucleotide excision repair is attenuated in bax-deficient mammalian cells following ultraviolet irradiation.
Experimental cell research 2002;278(2):158-65.
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2002: Bubb Robbin S; Komaki Ritsuko; Hachiya Tsutomu; Milas Ivan; Ro Jae Y; Langford Lauren; Sawaya Raymond; Putnam Joe B; Allen Pamela; Cox James D; McDonnell Timothy J; Brock William; Hong Waun K; Roth Jack A; Milas Luka
Association of Ki-67, p53, and bcl-2 expression of the primary non-small-cell lung cancer lesion with brain metastatic lesion.
International journal of radiation oncology, biology, physics 2002;53(5):1216-24.
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2002: Munshi A; McDonnell T J; Meyn R E
Chemotherapeutic agents enhance TRAIL-induced apoptosis in prostate cancer cells.
Cancer chemotherapy and pharmacology 2002;50(1):46-52.
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2002: Rassidakis George Z; Lai Raymond; McDonnell Timothy J; Cabanillas Fernando; Sarris Andreas H; Medeiros L Jeffrey
Overexpression of Mcl-1 in anaplastic large cell lymphoma cell lines and tumors.
The American journal of pathology 2002;160(6):2309-10.
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2002: O'Connor Sean L; Cho Jeong Hee; McDonnell Timothy J
The application of molecular techniques to solid tumors.
Seminars in diagnostic pathology 2002;19(2):94-103.
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2002: Delehedde Maryse; Lyon Malcolm; Vidyasagar Rishma; McDonnell Timothy J; Fernig David G
Hepatocyte growth factor/scatter factor binds to small heparin-derived oligosaccharides and stimulates the proliferation of human HaCaT keratinocytes.
The Journal of biological chemistry 2002;277(14):12456-62.
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2002: Honda Tsuyoshi; Kagawa Shunsuke; Spurgers Kevin B; Gjertsen Bjorn T; Roth Jack A; Fang Bingliang; Lowe Stephanie L; Norris James S; Meyn Raymond E; McDonnell Timothy J
A recombinant adenovirus expressing wild-type Bax induces apoptosis in prostate cancer cells independently of their Bcl-2 status and androgen sensitivity.
Cancer biology & therapy 2002;1(2):163-7.
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2002: Fizazi Karim; Martinez Luis A; Sikes Charles R; Johnston Dennis A; Stephens L Clifton; McDonnell Timothy J; Logothetis Christopher J; Trapman Jon; Pisters Louis L; Ordoñez Nelson G; Troncoso Patricia; Navone Nora M
The association of p21((WAF-1/CIP1)) with progression to androgen-independent prostate cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(3):775-81.
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2002: Rassidakis George Z; Medeiros L Jeffrey; McDonnell Timothy J; Viviani Simonetta; Bonfante Valeria; Nadali Gianpaolo; Vassilakopoulos Theodoros P; Giardini Roberto; Chilosi Marco; Kittas Christos; Gianni Alessandro M; Bonadonna Gianni; Pizzolo Giovanni; Pangalis Gerassimos A; Cabanillas Fernando; Sarris Andreas H
BAX expression in Hodgkin and Reed-Sternberg cells of Hodgkin's disease: correlation with clinical outcome.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(2):488-93.
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2002: Coombes Kevin R; Zhang Lin; Bueso-Ramos Carlos; Brisbay Shawn; Logothetis Christopher; Roth Jack; Keating Michael J; McDonnell Timothy J
TAD: a web interface and database for tissue microarrays.
Applied bioinformatics 2002;1(3):155-8.
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2001: Kurland J F; Kodym R; Story M D; Spurgers K B; McDonnell T J; Meyn R E
NF-kappaB1 (p50) homodimers contribute to transcription of the bcl-2 oncogene.
The Journal of biological chemistry 2001;276(48):45380-6.
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2001: Honda T; Gjertsen B T; Spurgers K B; Briones F; Lee S J; Hobbs M L; Meyn R E; Roth J A; Logothetis C; McDonnell T J
Restoration of bax in prostate cancer suppresses tumor growth and augments therapeutic cell death induction.
Anticancer research 2001;21(5):3141-6.
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2001: Lowe S L; Rubinchik S; Honda T; McDonnell T J; Dong J Y; Norris J S
Prostate-specific expression of Bax delivered by an adenoviral vector induces apoptosis in LNCaP prostate cancer cells.
Gene therapy 2001;8(18):1363-71.
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2001: Gomez-Manzano C; Mitlianga P; Fueyo J; Lee H Y; Hu M; Spurgers K B; Glass T L; Koul D; Liu T J; McDonnell T J; Yung W K
Transfer of E2F-1 to human glioma cells results in transcriptional up-regulation of Bcl-2.
Cancer research 2001;61(18):6693-7.
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2001: Rassidakis G Z; Sarris A H; Herling M; Ford R J; Cabanillas F; McDonnell T J; Medeiros L J
Differential expression of BCL-2 family proteins in ALK-positive and ALK-negative anaplastic large cell lymphoma of T/null-cell lineage.
The American journal of pathology 2001;159(2):527-35.
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2001: Munshi A; Pappas G; Honda T; McDonnell T J; Younes A; Li Y; Meyn R E
TRAIL (APO-2L) induces apoptosis in human prostate cancer cells that is inhibitable by Bcl-2.
Oncogene 2001;20(29):3757-65.
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2001: Kagawa S; Gu J; Honda T; McDonnell T J; Swisher S G; Roth J A; Fang B
Deficiency of caspase-3 in MCF7 cells blocks Bax-mediated nuclear fragmentation but not cell death.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(5):1474-80.
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2001: Delehedde M; Cho S H; Hamm R; Brisbay S; Ananthaswamy H N; Kripke M; McDonnell T J
Impact of Bcl-2 and Ha-ras on keratinocytes in organotypic culture.
The Journal of investigative dermatology 2001;116(3):366-73.
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2001: Cho S H; Delehedde M; Rodriguez-Villanueva J; Brisbay S; McDonnell T J
Bax gene disruption alters the epidermal response to ultraviolet irradiation and in vivo induced skin carcinogenesis.
International journal of molecular medicine 2001;7(3):235-41.
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2001: Fernandez A; Udagawa T; Schwesinger C; Beecken W; Achilles-Gerte E; McDonnell T; D'Amato R
Angiogenic potential of prostate carcinoma cells overexpressing bcl-2.
Journal of the National Cancer Institute 2001;93(3):208-13.
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2001: Schumacher G; Bruckheimer E M; Beham A W; Honda T; Brisbay S; Roth J A; Logothetis C; McDonnell T J
Molecular determinants of cell death induction following adenovirus-mediated gene transfer of wild-type p53 in prostate cancer cells.
International journal of cancer. Journal international du cancer 2001;91(2):159-66.
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2001: Pataer A; Smythe W R; Yu R; Fang B; McDonnell T; Roth J A; Swisher S G
Adenovirus-mediated Bak gene transfer induces apoptosis in mesothelioma cell lines.
The Journal of thoracic and cardiovascular surgery 2001;121(1):61-7.
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2000: Bruckheimer E M; Brisbay S; Johnson D J; Gingrich J R; Greenberg N; McDonnell T J
Bcl-2 accelerates multistep prostate carcinogenesis in vivo.
Oncogene 2000;19(46):5251-8.
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2000: Bruckheimer E M; Cho S; Brisbay S; Johnson D J; Gingrich J R; Greenberg N; McDonnell T J
The impact of bcl-2 expression and bax deficiency on prostate homeostasis in vivo.
Oncogene 2000;19(20):2404-12.
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2000: Bustamante J O; Michelette E R; Geibel J P; Hanover J A; McDonnell T J; Dean D A
Dendrimer-assisted patch-clamp sizing of nuclear pores.
Pflügers Archiv : European journal of physiology 2000;439(6):829-37.
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2000: Liu G; McDonnell T J; Montes de Oca Luna R; Kapoor M; Mims B; El-Naggar A K; Lozano G
High metastatic potential in mice inheriting a targeted p53 missense mutation.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(8):4174-9.
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2000: Navone N M; Rodriquez-Vargas M C; Benedict W F; Troncoso P; McDonnell T J; Zhou J H; Luthra R; Logothetis C J
TabBO: a model reflecting common molecular features of androgen-independent prostate cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(3):1190-7.
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2000: Pearson A S; Spitz F R; Swisher S G; Kataoka M; Sarkiss M G; Meyn R E; McDonnell T J; Cristiano R J; Roth J A
Up-regulation of the proapoptotic mediators Bax and Bak after adenovirus-mediated p53 gene transfer in lung cancer cells.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(3):887-90.
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2000: Tseng B S; Cavin S T; Booth F W; Olson E N; Marin M C; McDonnell T J; Butler I J
Pulmonary hypoplasia in the myogenin null mouse embryo.
American journal of respiratory cell and molecular biology 2000;22(3):304-15.
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2000: Pataer A; Fang B; Yu R; Kagawa S; Hunt K K; McDonnell T J; Roth J A; Swisher S G
Adenoviral Bak overexpression mediates caspase-dependent tumor killing.
Cancer research 2000;60(4):788-92.
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2000: Bustamante J O; Michelette E R; Geibel J P; Dean D A; Hanover J A; McDonnell T J
Calcium, ATP and nuclear pore channel gating.
Pflügers Archiv : European journal of physiology 2000;439(4):433-44.
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2000: Kagawa S; Pearson S A; Ji L; Xu K; McDonnell T J; Swisher S G; Roth J A; Fang B
A binary adenoviral vector system for expressing high levels of the proapoptotic gene bax.
Gene therapy 2000;7(1):75-9.
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2000: Fueyo J; Gomez-Manzano C; Alemany R; Lee P S; McDonnell T J; Mitlianga P; Shi Y X; Levin V A; Yung W K; Kyritsis A P
A mutant oncolytic adenovirus targeting the Rb pathway produces anti-glioma effect in vivo.
Oncogene 2000;19(1):2-12.
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2000: Spurgers K; Briones F; McDonnell T J
Prostate cancer: another piece to the molecular puzzle.
Advances in anatomic pathology 2000;7(1):9-12.
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2000: Blutt S E; McDonnell T J; Polek T C; Weigel N L
Calcitriol-induced apoptosis in LNCaP cells is blocked by overexpression of Bcl-2.
Endocrinology 2000;141(1):10-7.
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1999: Bruckheimer E M; Gjertsen B T; McDonnell T J
Implications of cell death regulation in the pathogenesis and treatment of prostate cancer.
Seminars in oncology 1999;26(4):382-98.
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1999: McDonnell T J; Montes de Oca Luna R; Cho S; Amelse L L; Chavez-Reyes A; Lozano G
Loss of one but not two mdm2 null alleles alters the tumour spectrum in p53 null mice.
The Journal of pathology 1999;188(3):322-8.
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1999: Davies M A; Koul D; Dhesi H; Berman R; McDonnell T J; McConkey D; Yung W K; Steck P A
Regulation of Akt/PKB activity, cellular growth, and apoptosis in prostate carcinoma cells by MMAC/PTEN.
Cancer research 1999;59(11):2551-6.
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1999: López-Guillermo A; Cabanillas F; McDonnell T I; McLaughlin P; Smith T; Pugh W; Hagemeister F; Rodríguez M A; Romaguera J E; Younes A; Sarris A H; Preti H A; Lee M S
Correlation of bcl-2 rearrangement with clinical characteristics and outcome in indolent follicular lymphoma.
Blood 1999;93(9):3081-7.
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1999: Logsdon M D; Meyn R E; Besa P C; Pugh W C; Stephens L C; Peters L J; Milas L; Cox J D; Cabanillas F; Brisbay S; Andersen M; McDonnell T J
Apoptosis and the Bcl-2 gene family -- patterns of expression and prognostic value in stage I and II follicular center lymphoma.
International journal of radiation oncology, biology, physics 1999;44(1):19-29.
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1999: Delehedde M; Cho S H; Sarkiss M; Brisbay S; Davies M; El-Naggar A K; McDonnell T J
Altered expression of bcl-2 family member proteins in nonmelanoma skin cancer.
Cancer 1999;85(7):1514-22.
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1998: Herrmann J L; Briones F; Brisbay S; Logothetis C J; McDonnell T J
Prostate carcinoma cell death resulting from inhibition of proteasome activity is independent of functional Bcl-2 and p53.
Oncogene 1998;17(22):2889-99.
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1998: Yu D; Jing T; Liu B; Yao J; Tan M; McDonnell T J; Hung M C
Overexpression of ErbB2 blocks Taxol-induced apoptosis by upregulation of p21Cip1, which inhibits p34Cdc2 kinase.
Molecular cell 1998;2(5):581-91.
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1998: Tormo M; Tari A M; McDonnell T J; Cabanillas F; Garcia-Conde J; Lopez-Berestein G
Apoptotic induction in transformed follicular lymphoma cells by Bcl-2 downregulation.
Leukemia & lymphoma 1998;30(3-4):367-79.
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1998: Beham A W; Sarkiss M; Brisbay S; Tu S M; von Eschenbach A C; McDonnell T J
Molecular correlates of bcl-2-enhanced growth following androgen-ablation in prostate carcinoma cells in vivo.
International journal of molecular medicine 1998;1(6):953-9.
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1998: Fueyo J; Gomez-Manzano C; Yung W K; Liu T J; Alemany R; McDonnell T J; Shi X; Rao J S; Levin V A; Kyritsis A P
Overexpression of E2F-1 in glioma triggers apoptosis and suppresses tumor growth in vitro and in vivo.
Nature medicine 1998;4(6):685-90.
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1998: Voehringer D W; McConkey D J; McDonnell T J; Brisbay S; Meyn R E
Bcl-2 expression causes redistribution of glutathione to the nucleus.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(6):2956-60.
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1998: Rodríguez-Villanueva J; Greenhalgh D; Wang X J; Bundman D; Cho S; Delehedde M; Roop D; McDonnell T J
Human keratin-1.bcl-2 transgenic mice aberrantly express keratin 6, exhibit reduced sensitivity to keratinocyte cell death induction, and are susceptible to skin tumor formation.
Oncogene 1998;16(7):853-63.
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1998: Beham A; Schumacher G; McDonnell T J; Marin M C; Jauch K W
[Bcl-2 inhibits p53-induced apoptosis after genotoxic damage by inhibitors of nuclear import of p53]
Langenbecks Archiv für Chirurgie. Supplement. Kongressband. Deutsche Gesellschaft für Chirurgie. Kongress 1998;115(Suppl I):113-7.
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1998: Gjertsen B T; Logothetis C J; McDonnell T J
Molecular regulation of cell death and therapeutic strategies for cell death induction in prostate carcinoma.
Cancer metastasis reviews 1998;17(4):345-51.
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1998: Bruckheimer E M; Cho S H; Sarkiss M; Herrmann J; McDonnell T J
The Bcl-2 gene family and apoptosis.
Advances in biochemical engineering/biotechnology 1998;62():75-105.
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1997: Beham A; Marin M C; Fernandez A; Herrmann J; Brisbay S; Tari A M; Lopez-Berestein G; Lozano G; Sarkiss M; McDonnell T J
Bcl-2 inhibits p53 nuclear import following DNA damage.
Oncogene 1997;15(23):2767-72.
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1997: Herrmann J L; Beham A W; Sarkiss M; Chiao P J; Rands M T; Bruckheimer E M; Brisbay S; McDonnell T J
Bcl-2 suppresses apoptosis resulting from disruption of the NF-kappa B survival pathway.
Experimental cell research 1997;237(1):101-9.
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1997: Pollack A; Wu C S; Czerniak B; Zagars G K; Benedict W F; McDonnell T J
Abnormal bcl-2 and pRb expression are independent correlates of radiation response in muscle-invasive bladder cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 1997;3(10):1823-9.
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1997: Hewitt S M; Hamada S; Monarres A; Kottical L V; Saunders G F; McDonnell T J
Transcriptional activation of the bcl-2 apoptosis suppressor gene by the paired box transcription factor PAX8.
Anticancer research 1997;17(5A):3211-5.
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1997: Mirkovic N; Voehringer D W; Story M D; McConkey D J; McDonnell T J; Meyn R E
Resistance to radiation-induced apoptosis in Bcl-2-expressing cells is reversed by depleting cellular thiols.
Oncogene 1997;15(12):1461-70.
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1997: Herrmann J L; Menter D G; Beham A; von Eschenbach A; McDonnell T J
Regulation of lipid signaling pathways for cell survival and apoptosis by bcl-2 in prostate carcinoma cells.
Experimental cell research 1997;234(2):442-51.
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1997: Gomez-Manzano C; Fueyo J; Kyritsis A P; McDonnell T J; Steck P A; Levin V A; Yung W K
Characterization of p53 and p21 functional interactions in glioma cells en route to apoptosis.
Journal of the National Cancer Institute 1997;89(14):1036-44.
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1997: Bruel A; Karsenty E; Schmid M; McDonnell T J; Lanotte M
Altered sensitivity to retinoid-induced apoptosis associated with changes in the subcellular distribution of Bcl-2.
Experimental cell research 1997;233(2):281-7.
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1997: McDonnell T J; Navone N M; Troncoso P; Pisters L L; Conti C; von Eschenbach A C; Brisbay S; Logothetis C J
Expression of bcl-2 oncoprotein and p53 protein accumulation in bone marrow metastases of androgen independent prostate cancer.
The Journal of urology 1997;157(2):569-74.
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1996: Sinicrope F A; Roddey G; McDonnell T J; Shen Y; Cleary K R; Stephens L C
Increased apoptosis accompanies neoplastic development in the human colorectum.
Clinical cancer research : an official journal of the American Association for Cancer Research 1996;2(12):1999-2006.
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1996: Herrmann J L; Bruckheimer E; McDonnell T J
Cell death signal transduction and Bcl-2 function.
Biochemical Society transactions 1996;24(4):1059-65.
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1996: Xie K; Huang S; Wang Y; Beltran P J; Juang S H; Dong Z; Reed J C; McDonnell T J; McConkey D J; Fidler I J
Bcl-2 protects cells from cytokine-induced nitric-oxide-dependent apoptosis.
Cancer immunology, immunotherapy : CII 1996;43(2):109-15.
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1996: McDonnell T J; Beham A; Sarkiss M; Andersen M M; Lo P
Importance of the Bcl-2 family in cell death regulation.
Experientia 1996;52(10-11):1008-17.
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1996: Roth J A; Nguyen D; Lawrence D D; Kemp B L; Carrasco C H; Ferson D Z; Hong W K; Komaki R; Lee J J; Nesbitt J C; Pisters K M; Putnam J B; Schea R; Shin D M; Walsh G L; Dolormente M M; Han C I; Martin F D; Yen N; Xu K; Stephens L C; McDonnell T J; Mukhopadhyay T; Cai D
Retrovirus-mediated wild-type p53 gene transfer to tumors of patients with lung cancer.
Nature medicine 1996;2(9):985-91.
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1996: Sastry K J; Marin M C; Nehete P N; McConnell K; el-Naggar A K; McDonnell T J
Expression of human immunodeficiency virus type I tat results in down-regulation of bcl-2 and induction of apoptosis in hematopoietic cells.
Oncogene 1996;13(3):487-93.
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1996: Steck K; McDonnell T; Sneige N; el-Naggar A
Flow cytometric analysis of apoptosis and bcl-2 in primary breast carcinomas: clinical and biological implications.
Cytometry 1996;24(2):116-22.
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1996: Marin M C; Fernandez A; Bick R J; Brisbay S; Buja L M; Snuggs M; McConkey D J; von Eschenbach A C; Keating M J; McDonnell T J
Apoptosis suppression by bcl-2 is correlated with the regulation of nuclear and cytosolic Ca2+.
Oncogene 1996;12(11):2259-66.
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1996: McConkey D J; Chandra J; Wright S; Plunkett W; McDonnell T J; Reed J C; Keating M
Apoptosis sensitivity in chronic lymphocytic leukemia is determined by endogenous endonuclease content and relative expression of BCL-2 and BAX.
Journal of immunology (Baltimore, Md. : 1950) 1996;156(7):2624-30.
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1996: Robertson L E; Plunkett W; McConnell K; Keating M J; McDonnell T J
Bcl-2 expression in chronic lymphocytic leukemia and its correlation with the induction of apoptosis and clinical outcome.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1996;10(3):456-9.
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1996: Sanchez Y; Lovell M; Marin M C; Wong P E; Wolf-Ledbetter M E; McDonnell T J; Killary A M
Tumor suppression and apoptosis of human prostate carcinoma mediated by a genetic locus within human chromosome 10pter-q11.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(6):2551-6.
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1996: Gomez-Manzano C; Fueyo J; Kyritsis A P; Steck P A; Roth J A; McDonnell T J; Steck K D; Levin V A; Yung W K
Adenovirus-mediated transfer of the p53 gene produces rapid and generalized death of human glioma cells via apoptosis.
Cancer research 1996;56(4):694-9.
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1995: Hewitt S M; Hamada S; McDonnell T J; Rauscher F J; Saunders G F
Regulation of the proto-oncogenes bcl-2 and c-myc by the Wilms' tumor suppressor gene WT1.
Cancer research 1995;55(22):5386-9.
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1995: Hsu B; Marin M C; el-Naggar A K; Stephens L C; Brisbay S; McDonnell T J
Evidence that c-myc mediated apoptosis does not require wild-type p53 during lymphomagenesis.
Oncogene 1995;11(1):175-9.
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1995: Hsu B; Marin M C; McDonnell T J
Cell death regulation during multistep lymphomagenesis.
Cancer letters 1995;94(1):17-23.
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1995: Tu S M; McConnell K; Marin M C; Campbell M L; Fernandez A; von Eschenbach A C; McDonnell T J
Combination adriamycin and suramin induces apoptosis in bcl-2 expressing prostate carcinoma cells.
Cancer letters 1995;93(2):147-55.
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1995: Liu T J; el-Naggar A K; McDonnell T J; Steck K D; Wang M; Taylor D L; Clayman G L
Apoptosis induction mediated by wild-type p53 adenoviral gene transfer in squamous cell carcinoma of the head and neck.
Cancer research 1995;55(14):3117-22.
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1995: Steck K D; McDonnell T J; el-Naggar A K
Flow cytometric analysis of apoptosis and bcl-2 in human solid neoplasms.
Cytometry 1995;20(2):154-61.
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1995: Rodriguez-Villanueva J; Colome M I; Brisbay S; McDonnell T J
The expression and localization of bcl-2 protein in normal skin and in non-melanoma skin cancers.
Pathology, research and practice 1995;191(5):391-8.
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1995: Marin M C; Hsu B; Stephens L C; Brisbay S; McDonnell T J
The functional basis of c-myc and bcl-2 complementation during multistep lymphomagenesis in vivo.
Experimental cell research 1995;217(2):240-7.
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1995: Rodríguez-Villanueva J; McDonnell T J
Induction of apoptotic cell death in non-melanoma skin cancer by interferon-alpha.
International journal of cancer. Journal international du cancer 1995;61(1):110-4.
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1995: Fernandez A; Fosdick L J; Marin M C; Diaz C; McDonnell T J; Ananthaswamy H N; McConkey D J
Differential regulation of endogenous endonuclease activation in isolated murine fibroblast nuclei by ras and bcl-2.
Oncogene 1995;10(4):769-74.
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1995: McDonnell T J; Meyn R E; Robertson L E
Implications of apoptotic cell death regulation in cancer therapy.
Seminars in cancer biology 1995;6(1):53-60.
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1994: Marin M C; Hsu B; Meyn R E; Donehower L A; el-Naggar A K; McDonnell T J
Evidence that p53 and bcl-2 are regulators of a common cell death pathway important for in vivo lymphomagenesis.
Oncogene 1994;9(11):3107-12.
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1994: Chandler D; el-Naggar A K; Brisbay S; Redline R W; McDonnell T J
Apoptosis and expression of the bcl-2 proto-oncogene in the fetal and adult human kidney: evidence for the contribution of bcl-2 expression to renal carcinogenesis.
Human pathology 1994;25(8):789-96.
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1994: Fernandez A; Marin M C; McDonnell T; Ananthaswamy H N
Differential sensitivity of normal and Ha-ras-transformed C3H mouse embryo fibroblasts to tumor necrosis factor: induction of bcl-2, c-myc, and manganese superoxide dismutase in resistant cells.
Oncogene 1994;9(7):2009-17.
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1993: McDonnell T J; Marin M C; Hsu B; Brisbay S M; McConnell K; Tu S M; Campbell M L; Rodriguez-Villanueva J
The bcl-2 oncogene: apoptosis and neoplasia.
Radiation research 1993;136(3):307-12.
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1993: McDonnell T J
Cell division versus cell death: a functional model of multistep neoplasia.
Molecular carcinogenesis 1993;8(4):209-13.
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1992: McDonnell T J; Troncoso P; Brisbay S M; Logothetis C; Chung L W; Hsieh J T; Tu S M; Campbell M L
Expression of the protooncogene bcl-2 in the prostate and its association with emergence of androgen-independent prostate cancer.
Cancer research 1992;52(24):6940-4.
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1991: Nuñez G; Hockenbery D; McDonnell T J; Sorensen C M; Korsmeyer S J
Bcl-2 maintains B cell memory.
Nature 1991;353(6339):71-3.
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1991: McDonnell T J; Korsmeyer S J
Progression from lymphoid hyperplasia to high-grade malignant lymphoma in mice transgenic for the t(14; 18).
Nature 1991;349(6306):254-6.
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1990: McDonnell T J; Nunez G; Platt F M; Hockenberry D; London L; McKearn J P; Korsmeyer S J
Deregulated Bcl-2-immunoglobulin transgene expands a resting but responsive immunoglobulin M and D-expressing B-cell population.
Molecular and cellular biology 1990;10(5):1901-7.
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1990: Korsmeyer S J; McDonnell T J; Nunez G; Hockenbery D; Young R
Bcl-2: B cell life, death and neoplasia.
Current topics in microbiology and immunology 1990;166():203-7.
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1989: McDonnell T J; Deane N; Platt F M; Nunez G; Jaeger U; McKearn J P; Korsmeyer S J
bcl-2-immunoglobulin transgenic mice demonstrate extended B cell survival and follicular lymphoproliferation.
Cell 1989;57(1):79-88.
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1987: Tate J M; McDonnell T J; Oberpriller J C; Oberpriller J O
Isolation of cardiac myocytes from the adult newt, Notophthalmus viridescens. an electron microscopic and quantitative light microscopic analysis.
Tissue & cell 1987;19(4):577-85.
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1984: McDonnell T J; Oberpriller J O
The response of the atrium to direct mechanical wounding in the adult heart of the newt, Notophthalmus viridescens. An electron-microscopic and autoradiographic study.
Cell and tissue research 1984;235(3):583-92.
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1983: McDonnell T J; Oberpriller J O
The atrial proliferative response following partial ventricular amputation in the heart of the adult newt. A light and electron microscopic autoradiographic study.
Tissue & cell 1983;15(3):351-63.
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