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Timothy McDonnell

Research Profile

Chemicals & Drugs

Disorders

Prostatic Neoplasms

Anatomy

Tumor Cells, Cultured

Living Beings

Physiology

Phenomena

Blotting, Western

Procedures

Genes & Molecular Sequences

Co-author Network

Publications

TOP 3
Zijun Y Xu-Monette; Michael Andreeff; Carlos E Bueso-Ramos; Timothy C Greiner; Yong Li; Timothy J McDonnell; L Jeffrey Medeiros; Robert Z Orlowski; Ken H Young
Dysfunction of the TP53 tumor suppressor gene in lymphoid malignancies.
Yi Zhou; William G Wierda; Michael J Keating; Timothy J McDonnell; L Jeffrey Medeiros; Guilin Tang; Sa A Wang
Therapy-related myeloid neoplasms following fludarabine, cyclophosphamide, and rituximab (FCR) treatment in patients with chronic lymphocytic leukemia/small lymphocytic lymphoma.
Yoshihiko Kadowaki; Nikhil S Chari; Albert E K Teo; Akihiko Hashi; Kevin B Spurgers; Timothy J McDonnell
PI3 Kinase inhibition on TRAIL-induced apoptosis correlates with androgen-sensitivity and p21 expression in prostate cancer cells.

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2012: Zijun Y Xu-Monette; Michael Andreeff; Carlos E Bueso-Ramos; Timothy C Greiner; Yong Li; Timothy J McDonnell; L Jeffrey Medeiros; Robert Z Orlowski; Ken H Young
Dysfunction of the TP53 tumor suppressor gene in lymphoid malignancies.
Blood 2012;119(16):3668-83.
2012: Yi Zhou; William G Wierda; Michael J Keating; Timothy J McDonnell; L Jeffrey Medeiros; Guilin Tang; Sa A Wang
Therapy-related myeloid neoplasms following fludarabine, cyclophosphamide, and rituximab (FCR) treatment in patients with chronic lymphocytic leukemia/small lymphocytic lymphoma.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2012;25(2):237-45.
2011: Yoshihiko Kadowaki; Nikhil S Chari; Albert E K Teo; Akihiko Hashi; Kevin B Spurgers; Timothy J McDonnell
PI3 Kinase inhibition on TRAIL-induced apoptosis correlates with androgen-sensitivity and p21 expression in prostate cancer cells.
Apoptosis : an international journal on programmed cell death 2011;16(6):627-35.
2010: Hong Jiang; Vanesa Martin; Candelaria Gomez-Manzano; David G Johnson; Marta Alonso; Erin White; Jing Xu; Timothy J McDonnell; Naoki Shinojima; Juan Fueyo
The RB-E2F1 pathway regulates autophagy.
Cancer research 2010;70(20):7882-93.
2010: Sa A Wang; K Jabbar; G Lu; S S Chen; Naomi Galili; Francisco Vega; Dan Jones; A Raza; Andrew Lamb; Guillermo Garcia-Manero; Timothy J McDonnell; L Jeffrey Medeiros
Trisomy 11 in myelodysplastic syndromes defines a unique group of disease with aggressive clinicopathologic features.
Leukemia 2010;24(4):740-7.
2010: Mei Liang; Xin Han; Saroj Vadhan-Raj; Martin Nguyen; Yu H Zhang; Michael Fernandez; Elias Drakos; Sergej Konoplev; C Cameron Yin; Roberto N Miranda; Timothy J McDonnell; L Jeffrey Medeiros; Carlos E Bueso-Ramos
HDM4 is overexpressed in mantle cell lymphoma and its inhibition induces p21 expression and apoptosis.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2010;23(3):381-91.
2009: Nikhil S Chari; Nicole L Pinaire; Lynnelle Thorpe; L Jeffrey Medeiros; Mark J Routbort; Timothy J McDonnell
The p53 tumor suppressor network in cancer and the therapeutic modulation of cell death.
Apoptosis : an international journal on programmed cell death 2009;14(4):336-47.
2009: Dimitra Tsavachidou; Timothy J McDonnell; Sijin Wen; Xuemei Wang; Funda Vakar-Lopez; Louis L Pisters; Curtis A Pettaway; Christopher G Wood; Kim-Anh Do; Peter F Thall; Clifton Stephens; Eleni Efstathiou; Robert Taylor; David G Menter; Patricia Troncoso; Scott M Lippman; Christopher J Logothetis; Jeri Kim
Selenium and vitamin E: cell type- and intervention-specific tissue effects in prostate cancer.
Journal of the National Cancer Institute 2009;101(5):306-20.
2008: Timothy J McDonnell; Nikhil S Chari; Jeong Hee Cho-Vega; Patricia Troncoso; Xuemei Wang; Carlos E Bueso-Ramos; Kevin R Coombes; Shawn Brisbay; Remigio Lopez; George Prendergast; Christopher Logothetis; Kim-Anh Do
Biomarker expression patterns that correlate with high grade features in treatment naive, organ-confined prostate cancer.
BMC medical genomics 2008;1():1.
2007: Jeong Hee Cho-Vega; Spiridon Tsavachidis; Kim-Anh Do; Junichi Nakagawa; L Jeffrey Medeiros; Timothy J McDonnell
Dicarbonyl/L-xylulose reductase: a potential biomarker identified by laser-capture microdissection-micro serial analysis of gene expression of human prostate adenocarcinoma.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2007;16(12):2615-22.
2007: Sangjun Lee; Nikhil S Chari; Hyung Woo Kim; Xuemei Wang; Dennis R Roop; Song H Cho; John DiGiovanni; Timothy J McDonnell
Cooperation of Ha-ras and Bcl-2 during multistep skin carcinogenesis.
Molecular carcinogenesis 2007;46(12):949-57.
2007: ME Leroux; Edmond Auzenne; Randall Evans; Numsen Hail; WC Spohn; Sukhen C Ghosh; David Farquhar; Timothy J McDonnell; Jim Klostergaard
Sphingolipids and the sphingosine kinase inhibitor, SKI II, induce BCL-2-independent apoptosis in human prostatic adenocarcinoma cells.
The Prostate 2007;67(15):1699-717.
2007: Nikhil S Chari; Timothy J McDonnell
The sonic hedgehog signaling network in development and neoplasia.
Advances in anatomic pathology 2007;14(5):344-52.
2007: Eleni Efstathiou; Patricia Troncoso; Sijin Wen; Kim-Anh Do; Curtis A Pettaway; Louis L Pisters; Timothy J McDonnell; Christopher J Logothetis
Initial modulation of the tumor microenvironment accounts for thalidomide activity in prostate cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(4):1224-31.
2007: Xin Han; Guillermo Garcia-Manero; Timothy J McDonnell; Guillermina Lozano; L Jeffrey Medeiros; Lianchun Xiao; Gary Rosner; Martin Nguyen; Michael Fernandez; Yasmine A Valentin-Vega; Juan A Barboza; Daniel M Jones; George Z Rassidakis; Hagop M Kantarjian; Carlos E Bueso-Ramos
HDM4 (HDMX) is widely expressed in adult pre-B acute lymphoblastic leukemia and is a potential therapeutic target.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2007;20(1):54-62.
2006: Li-Yan Khor; Michelle DeSilvio; Rile Li; Timothy J McDonnell; M Elizabeth H Hammond; William T Sause; Miljenko V Pilepich; Paul Okunieff; Howard M Sandler; Alan Pollack
Bcl-2 and bax expression and prostate cancer outcome in men treated with radiotherapy in Radiation Therapy Oncology Group protocol 86-10.
International journal of radiation oncology, biology, physics 2006;66(1):25-30.
2006: Kevin B Spurgers; David L Gold; Kevin R Coombes; Nicole L Bohnenstiehl; Brian Mullins; Raymond E Meyn; Christopher J Logothetis; Timothy J McDonnell
Identification of cell cycle regulatory genes as principal targets of p53-mediated transcriptional repression.
The Journal of biological chemistry 2006;281(35):25134-42.
2006: Kevin B Spurgers; Nikhil S Chari; N L Bohnenstiehl; Timothy J McDonnell
Molecular mediators of cell death in multistep carcinogenesis: a path to targeted therapy.
Cell death and differentiation 2006;13(8):1360-70.
2006: Jing Wang; Kim-Anh Do; Sijin Wen; Spyros Tsavachidis; Timothy J McDonnell; Christopher J Logothetis; Kevin R Coombes
Merging microarray data, robust feature selection, and predicting prognosis in prostate cancer.
Cancer informatics 2006;2():87-97.
2006: B M Broom; Timothy J McDonnell; Devika Subramanian
Predicting altered pathways using extendable scaffolds.
International journal of bioinformatics research and applications 2006;2(1):3-18.
2005: Jeri Kim; Peiyu Sun; Ying-Wai Lam; Patricia Troncoso; Anita L Sabichi; Richard J Babaian; Louis L Pisters; Curtis A Pettaway; Christopher G Wood; Scott M Lippman; Timothy J McDonnell; Ronald Lieberman; Christopher Logothetis; Shuk-Mei Ho
Changes in serum proteomic patterns by presurgical alpha-tocopherol and L-selenomethionine supplementation in prostate cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2005;14(7):1697-702.
2005: Carlos E Bueso-Ramos; Yunling Xu; Timothy J McDonnell; Shawn Brisbay; Sherry Pierce; Andrew Lamb; Gary Rosner; Guillermo Garcia-Manero
Protein expression of a triad of frequently methylated genes, p73, p57Kip2, and p15, has prognostic value in adult acute lymphocytic leukemia independently of its methylation status.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005;23(17):3932-9.
2005: Jeong Hee Cho-Vega; Patricia Troncoso; Kim-Anh Do; Carlo Rago; Xuemei Wang; Spiridon Tsavachidis; L Jeffrey Medeiros; Kevin B Spurgers; Christopher Logothetis; Timothy J McDonnell
Combined laser capture microdissection and serial analysis of gene expression from human tissue samples.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2005;18(4):577-84.
2005: Rebecca L H Bigelow; Emily Y Jen; Maryse DELEHEDDE; Nikhil S Chari; Timothy J McDonnell
Sonic hedgehog induces epidermal growth factor dependent matrix infiltration in HaCaT keratinocytes.
The Journal of investigative dermatology 2005;124(2):457-65.
2004: Vasily Assikis; Kim-Anh Do; Sijin Wen; Xuemei Wang; Jeong Hee Cho-Vega; Shawn Brisbay; Remigio Lopez; Christopher J Logothetis; Patricia Troncoso; Christos N Papandreou; Timothy J McDonnell
Clinical and biomarker correlates of androgen-independent, locally aggressive prostate cancer with limited metastatic potential.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(20):6770-8.
2004: Jeong Hee Cho-Vega; George Z Rassidakis; Joan H Admirand; Mauricio P Oyarzo; Preetha Ramalingam; Aris Paraguya; Timothy J McDonnell; Hesham M Amin; L Jeffrey Medeiros
MCL-1 expression in B-cell non-Hodgkin's lymphomas.
Human pathology 2004;35(9):1095-100.
2004: Erika Resetkova; Ana M Gonzalez-Angulo; Nour Sneige; Timothy J McDonnell; Aman U Buzdar; Shu-Wan Kau; Yuko Yamamura; James M Reuben; Gabriel N Hortobagyi; Massimo Cristofanilli
Prognostic value of P53, MDM-2, and MUC-1 for patients with inflammatory breast carcinoma.
Cancer 2004;101(5):913-7.
2004: Hesham M Amin; Timothy J McDonnell; Yupo Ma; Quan Lin; Yasushi Fujio; Keita Kunisada; Vasiliki Leventaki; Pamela Das; George Z Rassidakis; Cathy Cutler; L Jeffrey Medeiros; Raymond Lai
Selective inhibition of STAT3 induces apoptosis and G(1) cell cycle arrest in ALK-positive anaplastic large cell lymphoma.
Oncogene 2004;23(32):5426-34.
2004: Pradip K Majumder; Phillip G Febbo; Rachel Bikoff; Raanan Berger; Qi Xue; Louis M McMahon; Judith Manola; James Brugarolas; Timothy J McDonnell; Todd R Golub; Massimo Loda; Heidi A Lane; William R Sellers
mTOR inhibition reverses Akt-dependent prostate intraepithelial neoplasia through regulation of apoptotic and HIF-1-dependent pathways.
Nature medicine 2004;10(6):594-601.
2004: Louis L Pisters; Curtis A Pettaway; Patricia Troncoso; Timothy J McDonnell; L Clifton Stephens; Christopher G Wood; Kim-Anh Do; Shawn Brisbay; Xuemei Wang; Elizabeth A Hossan; Robert B Evans; Cindy Soto; Marc G Jacobson; Karen Parker; James A Merritt; Mitchell S Steiner; Christopher J Logothetis
Evidence that transfer of functional p53 protein results in increased apoptosis in prostate cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(8):2587-93.
2004: Tsuyoshi Honda; Simona Coppola; Lina Ghibelli; Song H Cho; Shunsuke Kagawa; Kevin B Spurgers; Shawn Brisbay; Jack A Roth; Raymond E Meyn; Bingliang Fang; Timothy J McDonnell
GSH depletion enhances adenoviral bax-induced apoptosis in lung cancer cells.
Cancer gene therapy 2004;11(4):249-55.
2004: Charles J Rosser; Motoyoshi Tanaka; Louis L Pisters; Noriyoshi Tanaka; Lawrence B Levy; David C Hoover; H Barton Grossman; Timothy J McDonnell; Deborah A Kuban; Raymond E Meyn
Adenoviral-mediated PTEN transgene expression sensitizes Bcl-2-expressing prostate cancer cells to radiation.
Cancer gene therapy 2004;11(4):273-9.
2004: Kevin B Spurgers; Kevin R Coombes; Raymond E Meyn; David L Gold; Christopher J Logothetis; Terry J Johnson; Timothy J McDonnell
A comprehensive assessment of p53-responsive genes following adenoviral-p53 gene transfer in Bcl-2-expressing prostate cancer cells.
Oncogene 2004;23(9):1712-23.
2004: Do-Hyun Nam; Kwan Park; Chaehwa Park; Young-Hyuck Im; Mi-Hyun Kim; Sangjun Lee; Seung-Chyul Hong; Hyung-Jin Shin; Jong-Hyun Kim; Whan Eoh; Timothy J McDonnell
Intracranial inhibition of glioma cell growth by cyclooxygenase-2 inhibitor celecoxib.
Oncology reports 2004;11(2):263-8.
2004: Rebecca L H Bigelow; Nikhil S Chari; Anne Birgitte Unden; Kevin B Spurgers; Sangjun Lee; Dennis R Roop; Rune Toftgard; Timothy J McDonnell
Transcriptional regulation of bcl-2 mediated by the sonic hedgehog signaling pathway through gli-1.
The Journal of biological chemistry 2004;279(2):1197-205.
2004: Elias Drakos; George Z Rassidakis; Raymond Lai; Marco Herling; Sean L O'Connor; Annette Schmitt-Graeff; Timothy J McDonnell; L Jeffrey Medeiros
Caspase-3 activation in systemic anaplastic large-cell lymphoma.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2004;17(1):109-16.
2003: Hesham M Amin; L Jeffrey Medeiros; Yupo Ma; Marianna Feretzaki; Pamela Das; Vasiliki Leventaki; George Z Rassidakis; Sean L O'Connor; Timothy J McDonnell; Raymond Lai
Inhibition of JAK3 induces apoptosis and decreases anaplastic lymphoma kinase activity in anaplastic large cell lymphoma.
Oncogene 2003;22(35):5399-407.
2003: Anne S Tsao; Timothy J McDonnell; Stephen Lam; Joe B Putnam; Nebiyou Bekele; Waun Ki Hong; Jonathan M Kurie
Increased phospho-AKT (Ser(473)) expression in bronchial dysplasia: implications for lung cancer prevention studies.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2003;12(7):660-4.
2003: Nand K Sah; Anupama Munshi; John F Kurland; Timothy J McDonnell; Bing Su; Raymond E Meyn
Translation inhibitors sensitize prostate cancer cells to apoptosis induced by tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) by activating c-Jun N-terminal kinase.
The Journal of biological chemistry 2003;278(23):20593-602.
2003: George Z Rassidakis; Dan Jones; Raymond Lai; Preetha Ramalingam; Andreas H Sarris; Timothy J McDonnell; L Jeffrey Medeiros
BCL-2 family proteins in peripheral T-cell lymphomas: correlation with tumour apoptosis and proliferation.
The Journal of pathology 2003;200(2):240-8.
2003: Hesham M Amin; Timothy J McDonnell; L Jeffrey Medeiros; George Z Rassidakis; Vasiliki Leventaki; Sean L O'Connor; Michael J Keating; Raymond Lai
Characterization of 4 mantle cell lymphoma cell lines.
Archives of pathology & laboratory medicine 2003;127(4):424-31.
2003: Alan Pollack; Didier Cowen; Patricia Troncoso; Gunar K Zagars; Andrew C von Eschenbach; Marvin L Meistrich; Timothy J McDonnell
Molecular markers of outcome after radiotherapy in patients with prostate carcinoma: Ki-67, bcl-2, bax, and bcl-x.
Cancer 2003;97(7):1630-8.
2003: Olivia Aranha; Robert Grignon; Neelesh Fernandes; Timothy J McDonnell; David P Wood Jr; Asfar S Azmi
Suppression of human prostate cancer cell growth by ciprofloxacin is associated with cell cycle arrest and apoptosis.
International journal of oncology 2003;22(4):787-94.
2003: Elizabeth M Bruckheimer; Kevin B Spurgers; Nancy L Weigel; Christopher Logothetis; Timothy J McDonnell
Regulation of Bcl-2 expression by dihydrotestosterone in hormone sensitive LNCaP-FGC prostate cancer cells.
The Journal of urology 2003;169(4):1553-7.
2003: George Z Rassidakis; Francois Claret; Raymond Lai; Qingxiu Zhang; Andreas H Sarris; Timothy J McDonnell; L Jeffrey Medeiros
Expression of p27(Kip1) and c-Jun activation binding protein 1 are inversely correlated in systemic anaplastic large cell lymphoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(3):1121-8.
2003: Ivan Milas; Ritsuko Komaki; Tsutomu Hachiya; Robbin S Bubb; Jae Y Ro; Lauren Langford; Raymond Sawaya; Joe B Putnam; Pamela Allen; James D Cox; Timothy J McDonnell; William A Brock; Waun Ki Hong; Jack A Roth; Luka Milas
Epidermal growth factor receptor, cyclooxygenase-2, and BAX expression in the primary non-small cell lung cancer and brain metastases.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(3):1070-6.
2003: James B DuHadaway; Frank J Lynch; Shawn Brisbay; Carlos E Bueso-Ramos; Patricia Troncoso; Timothy J McDonnell; George C Prendergast
Immunohistochemical analysis of Bin1/Amphiphysin II in human tissues: diverse sites of nuclear expression and losses in prostate cancer.
Journal of cellular biochemistry 2003;88(3):635-42.
2003: Stephen G Swisher; Jack A Roth; Ritsuko Komaki; Jian Gu; J Jack Lee; Marshall Hicks; Jae Y Ro; Waun Ki Hong; James A Merritt; Kamaran Ahrar; N Edward Atkinson; Arlene M Correa; Marcelo Dolormente; Linda Dreiling; Adel K El-Naggar; Frank Fossella; Rhodette Francisco; Bonnie Glisson; Susan Grammer; Roy Herbst; Armando Huaringa; Bonnie Kemp; Fadlo R Khuri; Jonathan M Kurie; Zhongxio Liao; Timothy J McDonnell; Rudolfo Morice; Frank Morello; Reginald Munden; Vassiliki Papadimitrakopoulou; Katherine M W Pisters; Joe B Putnam; Arcenio J Sarabia; Thomas Shelton; Craig Stevens; Daniel M Shin; William R Smythe; Ara A Vaporciyan; Garrett L Walsh; Min Yin
Induction of p53-regulated genes and tumor regression in lung cancer patients after intratumoral delivery of adenoviral p53 (INGN 201) and radiation therapy.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(1):93-101.
2003: Joseph D Khoury; L Jeffrey Medeiros; George Z Rassidakis; Timothy J McDonnell; Lynne V Abruzzo; Raymond Lai
Expression of Mcl-1 in mantle cell lymphoma is associated with high-grade morphology, a high proliferative state, and p53 overexpression.
The Journal of pathology 2003;199(1):90-7.
2003: Raymond Lai; George Z Rassidakis; L Jeffrey Medeiros; Vasiliki Leventaki; Michael Keating; Timothy J McDonnell
Expression of STAT3 and its phosphorylated forms in mantle cell lymphoma cell lines and tumours.
The Journal of pathology 2003;199(1):84-9.
2002: George Z Rassidakis; L Jeffrey Medeiros; Theodoros P Vassilakopoulos; Simonetta Viviani; Valeria Bonfante; Gianpaolo Nadali; Marco Herling; Maria K Angelopoulou; Roberto Giardini; Marco Chilosi; Christos Kittas; Timothy J McDonnell; Gianni Bonadonna; ALESSANDRO MASSIMO GIANNI; Giovanni Pizzolo; Gerassimos A Pangalis; Fernando Cabanillas; Andreas H Sarris
BCL-2 expression in Hodgkin and Reed-Sternberg cells of classical Hodgkin disease predicts a poorer prognosis in patients treated with ABVD or equivalent regimens.
Blood 2002;100(12):3935-41.
2002: Qiang G Dong; Guido M Sclabas; Shuichi Fujioka; Christian Schmidt; Bailu Peng; TianAi Wu; Ming Tsao; Douglas B Evans; James L Abbruzzese; Timothy J McDonnell; Paul J Chiao
The function of multiple IkappaB : NF-kappaB complexes in the resistance of cancer cells to Taxol-induced apoptosis.
Oncogene 2002;21(42):6510-9.
2002: George Z Rassidakis; Dan Jones; Athanasios Thomaides; Filiz Sen; Raymond Lai; Fernando Cabanillas; Timothy J McDonnell; L Jeffrey Medeiros
Apoptotic rate in peripheral T-cell lymphomas. A study using a tissue microarray with validation on full tissue sections.
American journal of clinical pathology 2002;118(3):328-34.
2002: Raymond Lai; Timothy J McDonnell; Sean L O'Connor; L Jeffrey Medeiros; R Oudat; Michael Keating; M B Morgan; Tyler J Curiel; Richard J Ford
Establishment and characterization of a new mantle cell lymphoma cell line, Mino.
Leukemia research 2002;26(9):849-55.
2002: Song Cho; Sean L O'Connor; Timothy J McDonnell
Evidence that nucleotide excision repair is attenuated in bax-deficient mammalian cells following ultraviolet irradiation.
Experimental cell research 2002;278(2):158-65.
2002: Robbin S Bubb; Ritsuko Komaki; Tsutomu Hachiya; Ivan Milas; Jae Y Ro; Lauren Langford; Raymond Sawaya; Joe B Putnam; Pamela Allen; James D Cox; Timothy J McDonnell; William A Brock; Waun Ki Hong; Jack A Roth; Luka Milas
Association of Ki-67, p53, and bcl-2 expression of the primary non-small-cell lung cancer lesion with brain metastatic lesion.
International journal of radiation oncology, biology, physics 2002;53(5):1216-24.
2002: Anupama Munshi; Timothy J McDonnell; Raymond E Meyn
Chemotherapeutic agents enhance TRAIL-induced apoptosis in prostate cancer cells.
Cancer chemotherapy and pharmacology 2002;50(1):46-52.
2002: George Z Rassidakis; Raymond Lai; Timothy J McDonnell; Fernando Cabanillas; Andreas H Sarris; L Jeffrey Medeiros
Overexpression of Mcl-1 in anaplastic large cell lymphoma cell lines and tumors.
The American journal of pathology 2002;160(6):2309-10.
2002: Sean L O'Connor; Jeong Hee Cho; Timothy J McDonnell
The application of molecular techniques to solid tumors.
Seminars in diagnostic pathology 2002;19(2):94-103.
2002: Maryse DELEHEDDE; Malcolm Lyon; Rishma Vidyasagar; Timothy J McDonnell; David G Fernig
Hepatocyte growth factor/scatter factor binds to small heparin-derived oligosaccharides and stimulates the proliferation of human HaCaT keratinocytes.
The Journal of biological chemistry 2002;277(14):12456-62.
2002: Tsuyoshi Honda; Shunsuke Kagawa; Kevin B Spurgers; Bjorn T Gjertsen; Jack A Roth; Bingliang Fang; Stephanie L Lowe; james norris; Raymond E Meyn; Timothy J McDonnell
A recombinant adenovirus expressing wild-type Bax induces apoptosis in prostate cancer cells independently of their Bcl-2 status and androgen sensitivity.
Cancer biology & therapy 2002;1(2):163-7.
2002: Karim Fizazi; Luis A. Martinez; Charles R Sikes; Dennis A Johnston; L Clifton Stephens; Timothy J McDonnell; Christopher J Logothetis; Jon Trapman; Louis L Pisters; Nelson G Ordoñez; Patricia Troncoso; Nora M Navone
The association of p21((WAF-1/CIP1)) with progression to androgen-independent prostate cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(3):775-81.
2002: George Z Rassidakis; L Jeffrey Medeiros; Timothy J McDonnell; Simonetta Viviani; Valeria Bonfante; Gianpaolo Nadali; Theodoros P Vassilakopoulos; Roberto Giardini; Marco Chilosi; Christos Kittas; ALESSANDRO MASSIMO GIANNI; Gianni Bonadonna; Giovanni Pizzolo; Gerassimos A Pangalis; Fernando Cabanillas; Andreas H Sarris
BAX expression in Hodgkin and Reed-Sternberg cells of Hodgkin's disease: correlation with clinical outcome.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(2):488-93.
2002: Kevin R Coombes; Lin Zhang; Carlos E Bueso-Ramos; Shawn Brisbay; Christopher Logothetis; Jack Roth; Michael J Keating; Timothy J McDonnell
TAD: a web interface and database for tissue microarrays.
Applied bioinformatics 2002;1(3):155-8.
2001: John F Kurland; R Kodym; MD Story; Kevin B Spurgers; Timothy J McDonnell; Raymond E Meyn
NF-kappaB1 (p50) homodimers contribute to transcription of the bcl-2 oncogene.
The Journal of biological chemistry 2001;276(48):45380-6.
2001: Candelaria Gomez-Manzano; Paraskevi G Mitlianga; Juan Fueyo; Ho-Young Lee; Min Hu; Kevin B Spurgers; Tricia L Glass; Dimpy Koul; Ta-Jen Liu; Timothy J McDonnell; W K Alfred Yung
Transfer of E2F-1 to human glioma cells results in transcriptional up-regulation of Bcl-2.
Cancer research 2001;61(18):6693-7.
2001: T Honda; Bjorn T Gjertsen; Kevin B Spurgers; F Briones; S J Lee; Marvette L Hobbs; Raymond E Meyn; Jack A Roth; Christopher Logothetis; Timothy J McDonnell
Restoration of bax in prostate cancer suppresses tumor growth and augments therapeutic cell death induction.
Anticancer research 2001;21(5):3141-6.
2001: Stephanie L Lowe; Semyon Rubinchik; T Honda; Timothy J McDonnell; Jian-Yun Dong; james norris
Prostate-specific expression of Bax delivered by an adenoviral vector induces apoptosis in LNCaP prostate cancer cells.
Gene therapy 2001;8(18):1363-71.
2001: George Z Rassidakis; Andreas H Sarris; Marco Herling; Richard J Ford; Fernando Cabanillas; Timothy J McDonnell; L Jeffrey Medeiros
Differential expression of BCL-2 family proteins in ALK-positive and ALK-negative anaplastic large cell lymphoma of T/null-cell lineage.
The American journal of pathology 2001;159(2):527-35.
2001: Anupama Munshi; G Pappas; T Honda; Timothy J McDonnell; Anas Younes; Yang Li; Raymond E Meyn
TRAIL (APO-2L) induces apoptosis in human prostate cancer cells that is inhibitable by Bcl-2.
Oncogene 2001;20(29):3757-65.
2001: S Kagawa; Jian Gu; T Honda; Timothy J McDonnell; Stephen G Swisher; Jack A Roth; Bingliang Fang
Deficiency of caspase-3 in MCF7 cells blocks Bax-mediated nuclear fragmentation but not cell death.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(5):1474-80.
2001: Maryse DELEHEDDE; Song H Cho; R Hamm; Shawn Brisbay; Honnavara N Ananthaswamy; Margaret L Kripke; Timothy J McDonnell
Impact of Bcl-2 and Ha-ras on keratinocytes in organotypic culture.
The Journal of investigative dermatology 2001;116(3):366-73.
2001: Song H Cho; Maryse DELEHEDDE; J Rodriguez-Villanueva; Shawn Brisbay; Timothy J McDonnell
Bax gene disruption alters the epidermal response to ultraviolet irradiation and in vivo induced skin carcinogenesis.
International journal of molecular medicine 2001;7(3):235-41.
2001: Antonio Fernandez; Taturo Udagawa; C Schwesinger; Wolf-Dietrich Beecken; E Achilles-Gerte; Timothy J McDonnell; Robert J D'Amato
Angiogenic potential of prostate carcinoma cells overexpressing bcl-2.
Journal of the National Cancer Institute 2001;93(3):208-13.
2001: Guido Schumacher; Elizabeth M Bruckheimer; AW Beham; T Honda; Shawn Brisbay; Jack A Roth; Christopher Logothetis; Timothy J McDonnell
Molecular determinants of cell death induction following adenovirus-mediated gene transfer of wild-type p53 in prostate cancer cells.
International journal of cancer. Journal international du cancer 2001;91(2):159-66.
2001: Abujiang Pataer; W Roy Smythe; R Yu; Bingliang Fang; Timothy J McDonnell; Jack A Roth; Stephen G Swisher
Adenovirus-mediated Bak gene transfer induces apoptosis in mesothelioma cell lines.
The Journal of thoracic and cardiovascular surgery 2001;121(1):61-7.
2000: Elizabeth M Bruckheimer; Shawn Brisbay; D J Johnson; J R Gingrich; N Greenberg; Timothy J McDonnell
Bcl-2 accelerates multistep prostate carcinogenesis in vivo.
Oncogene 2000;19(46):5251-8.
2000: Elizabeth M Bruckheimer; S Cho; Shawn Brisbay; D J Johnson; J R Gingrich; N Greenberg; Timothy J McDonnell
The impact of bcl-2 expression and bax deficiency on prostate homeostasis in vivo.
Oncogene 2000;19(20):2404-12.
2000: Geng Liu; Timothy J McDonnell; R Montes de Oca Luna; M Kapoor; B Mims; Adel K El-Naggar; Guillermina Lozano
High metastatic potential in mice inheriting a targeted p53 missense mutation.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(8):4174-9.
2000: Jose Bustamante; E R Michelette; John Peter Geibel; John Hanover; Timothy J McDonnell; D A Dean
Dendrimer-assisted patch-clamp sizing of nuclear pores.
Pflügers Archiv : European journal of physiology 2000;439(6):829-37.
2000: Nora M Navone; M C Rodriquez-Vargas; William F Benedict; Patricia Troncoso; Timothy J McDonnell; J H Zhou; Rajyalakshmi Luthra; Christopher J Logothetis
TabBO: a model reflecting common molecular features of androgen-independent prostate cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(3):1190-7.
2000: A Scott Pearson; FR Spitz; Stephen G Swisher; M Kataoka; Mona Sarkiss; R E Meyn; Timothy J McDonnell; Richard J Cristiano; Jack A Roth
Up-regulation of the proapoptotic mediators Bax and Bak after adenovirus-mediated p53 gene transfer in lung cancer cells.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(3):887-90.
2000: BS Tseng; S T Cavin; Frank W Booth; E N Olson; MC Marin; Timothy J McDonnell; Ian J Butler
Pulmonary hypoplasia in the myogenin null mouse embryo.
American journal of respiratory cell and molecular biology 2000;22(3):304-15.
2000: Abujiang Pataer; Bingliang Fang; R Yu; S Kagawa; Kelly K Hunt; Timothy J McDonnell; Jack A Roth; Stephen G Swisher
Adenoviral Bak overexpression mediates caspase-dependent tumor killing.
Cancer research 2000;60(4):788-92.
2000: Jose Bustamante; E R Michelette; John Peter Geibel; D A Dean; John Hanover; Timothy J McDonnell
Calcium, ATP and nuclear pore channel gating.
Pflügers Archiv : European journal of physiology 2000;439(4):433-44.
2000: Juan Fueyo; Candelaria Gomez-Manzano; Ramon Alemany; P S Lee; Timothy J McDonnell; Paraskevi G Mitlianga; Yue-Xi Shi; Victor Levin; W K Alfred Yung; Athanassios P Kyritsis
A mutant oncolytic adenovirus targeting the Rb pathway produces anti-glioma effect in vivo.
Oncogene 2000;19(1):2-12.
2000: S Kagawa; S A Pearson; L Ji; K Xu; Timothy J McDonnell; S G Swisher; Jack A Roth; Bingliang Fang
A binary adenoviral vector system for expressing high levels of the proapoptotic gene bax.
Gene therapy 2000;7(1):75-9.
2000: Kevin B Spurgers; F Briones; Timothy J McDonnell
Prostate cancer: another piece to the molecular puzzle.
Advances in anatomic pathology 2000;7(1):9-12.
2000: Sarah E Blutt; Timothy J McDonnell; Tara C Polek; Nancy L Weigel
Calcitriol-induced apoptosis in LNCaP cells is blocked by overexpression of Bcl-2.
Endocrinology 2000;141(1):10-7.
1999: Elizabeth M Bruckheimer; Bjorn T Gjertsen; Timothy J McDonnell
Implications of cell death regulation in the pathogenesis and treatment of prostate cancer.
Seminars in oncology 1999;26(4):382-98.
1999: Timothy J McDonnell; R Montes de Oca Luna; S Cho; Lisa L Amelse; Arturo Chavez-Reyes; Guillermina Lozano
Loss of one but not two mdm2 null alleles alters the tumour spectrum in p53 null mice.
The Journal of pathology 1999;188(3):322-8.
1999: Michael A Davies; Dimpy Koul; H Dhesi; R Berman; Timothy J McDonnell; David J McConkey; W K Alfred Yung; PA Steck
Regulation of Akt/PKB activity, cellular growth, and apoptosis in prostate carcinoma cells by MMAC/PTEN.
Cancer research 1999;59(11):2551-6.
1999: A López-Guillermo; Fernando Cabanillas; Timothy J McDonnell; Peter McLaughlin; T Smith; WC Pugh; Fredrick Hagemeister; MA Rodríguez; Jorge Romaguera; Anas Younes; Andreas H Sarris; H Alejandro Preti; Ming-Sheng Lee
Correlation of bcl-2 rearrangement with clinical characteristics and outcome in indolent follicular lymphoma.
Blood 1999;93(9):3081-7.
1999: MD Logsdon; Raymond E Meyn; PC Besa; WC Pugh; L Clifton Stephens; LJ Peters; Luka Milas; James D Cox; Fernando Cabanillas; Shawn Brisbay; M Andersen; Timothy J McDonnell
Apoptosis and the Bcl-2 gene family -- patterns of expression and prognostic value in stage I and II follicular center lymphoma.
International journal of radiation oncology, biology, physics 1999;44(1):19-29.
1999: Maryse DELEHEDDE; Song H Cho; Mona Sarkiss; Shawn Brisbay; M Davies; Adel K El-Naggar; Timothy J McDonnell
Altered expression of bcl-2 family member proteins in nonmelanoma skin cancer.
Cancer 1999;85(7):1514-22.
1998: JL Herrmann; F Briones; Shawn Brisbay; Christopher J Logothetis; Timothy J McDonnell
Prostate carcinoma cell death resulting from inhibition of proteasome activity is independent of functional Bcl-2 and p53.
Oncogene 1998;17(22):2889-99.
1998: Dihua Yu; Tong Jing; Bolin Liu; J Yao; Ming Tan; Timothy J McDonnell; Mien-Chie Hung
Overexpression of ErbB2 blocks Taxol-induced apoptosis by upregulation of p21Cip1, which inhibits p34Cdc2 kinase.
Molecular cell 1998;2(5):581-91.
1998: Mar Tormo; Ana M Tari; Timothy J McDonnell; Fernando Cabanillas; Javier Garcia-Conde; Gabriel Lopez-Berestein
Apoptotic induction in transformed follicular lymphoma cells by Bcl-2 downregulation.
Leukemia & lymphoma 1998;30(3-4):367-79.
1998: AW Beham; Mona Sarkiss; Shawn Brisbay; Shi-Ming Tu; Andrew C von Eschenbach; Timothy J McDonnell
Molecular correlates of bcl-2-enhanced growth following androgen-ablation in prostate carcinoma cells in vivo.
International journal of molecular medicine 1998;1(6):953-9.
1998: Juan Fueyo; Candelaria Gomez-Manzano; W K Alfred Yung; Ta-Jen Liu; Ramon Alemany; Timothy J McDonnell; X Shi; Jasti Sambasiva Rao; Victor Levin; Athanassios P Kyritsis
Overexpression of E2F-1 in glioma triggers apoptosis and suppresses tumor growth in vitro and in vivo.
Nature medicine 1998;4(6):685-90.
1998: David Voehringer; David J McConkey; Timothy J McDonnell; Shawn Brisbay; Raymond E Meyn
Bcl-2 expression causes redistribution of glutathione to the nucleus.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(6):2956-60.
1998: J Rodríguez-Villanueva; D Greenhalgh; Xiao-Jing Wang; D Bundman; S Cho; Maryse DELEHEDDE; D Roop; Timothy J McDonnell
Human keratin-1.bcl-2 transgenic mice aberrantly express keratin 6, exhibit reduced sensitivity to keratinocyte cell death induction, and are susceptible to skin tumor formation.
Oncogene 1998;16(7):853-63.
1998: A Beham; Guido Schumacher; Timothy J McDonnell; MC Marin; Karl-Walter Jauch
[Bcl-2 inhibits p53-induced apoptosis after genotoxic damage by inhibitors of nuclear import of p53].
Langenbecks Archiv für Chirurgie. Supplement. Kongressband. Deutsche Gesellschaft für Chirurgie. Kongress 1998;115(Suppl I):113-7.
1998: Bjorn T Gjertsen; Christopher J Logothetis; Timothy J McDonnell
Molecular regulation of cell death and therapeutic strategies for cell death induction in prostate carcinoma.
Cancer metastasis reviews 1998;17(4):345-51.
1998: Elizabeth M Bruckheimer; Song H Cho; Mona Sarkiss; J Herrmann; Timothy J McDonnell
The Bcl-2 gene family and apoptosis.
Advances in biochemical engineering/biotechnology 1998;62():75-105.
1997: AW Beham; MC Marin; A Fernandez; J Herrmann; Shawn Brisbay; Ana M Tari; Gabriel Lopez-Berestein; Guillermina Lozano; Mona Sarkiss; Timothy J McDonnell
Bcl-2 inhibits p53 nuclear import following DNA damage.
Oncogene 1997;15(23):2767-72.
1997: JL Herrmann; AW Beham; Mona Sarkiss; Paul J Chiao; M T Rands; Elizabeth M Bruckheimer; Shawn Brisbay; Timothy J McDonnell
Bcl-2 suppresses apoptosis resulting from disruption of the NF-kappa B survival pathway.
Experimental cell research 1997;237(1):101-9.
1997: Alan Pollack; C S Wu; Bogdan Czerniak; Gunar K Zagars; William F Benedict; Timothy J McDonnell
Abnormal bcl-2 and pRb expression are independent correlates of radiation response in muscle-invasive bladder cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 1997;3(10):1823-9.
1997: N Mirkovic; David Voehringer; Michael D Story; David J McConkey; Timothy J McDonnell; Raymond E Meyn
Resistance to radiation-induced apoptosis in Bcl-2-expressing cells is reversed by depleting cellular thiols.
Oncogene 1997;15(12):1461-70.
1997: S M Hewitt; S Hamada; A Monarres; L V Kottical; Grady F Saunders; Timothy J McDonnell
Transcriptional activation of the bcl-2 apoptosis suppressor gene by the paired box transcription factor PAX8.
Anticancer research 1997;17(5A):3211-5.
1997: JL Herrmann; David G Menter; AW Beham; A von Eschenbach; Timothy J McDonnell
Regulation of lipid signaling pathways for cell survival and apoptosis by bcl-2 in prostate carcinoma cells.
Experimental cell research 1997;234(2):442-51.
1997: Candelaria Gomez-Manzano; Juan Fueyo; Athanassios P Kyritsis; Timothy J McDonnell; PA Steck; Victor Levin; W K Alfred Yung
Characterization of p53 and p21 functional interactions in glioma cells en route to apoptosis.
Journal of the National Cancer Institute 1997;89(14):1036-44.
1997: A Bruel; E Karsenty; M Schmid; Timothy J McDonnell; Michel Lanotte
Altered sensitivity to retinoid-induced apoptosis associated with changes in the subcellular distribution of Bcl-2.
Experimental cell research 1997;233(2):281-7.
1997: Timothy J McDonnell; Nora M Navone; Patricia Troncoso; Louis L Pisters; C Conti; Andrew C von Eschenbach; Shawn Brisbay; Christopher J Logothetis
Expression of bcl-2 oncoprotein and p53 protein accumulation in bone marrow metastases of androgen independent prostate cancer.
The Journal of urology 1997;157(2):569-74.
1996: Frank A Sinicrope; G Roddey; Timothy J McDonnell; Yu Shen; Karen R Cleary; L Clifton Stephens
Increased apoptosis accompanies neoplastic development in the human colorectum.
Clinical cancer research : an official journal of the American Association for Cancer Research 1996;2(12):1999-2006.
1996: JL Herrmann; Elizabeth M Bruckheimer; Timothy J McDonnell
Cell death signal transduction and Bcl-2 function.
Biochemical Society transactions 1996;24(4):1059-65.
1996: Timothy J McDonnell; AW Beham; Mona Sarkiss; M M Andersen; P Lo
Importance of the Bcl-2 family in cell death regulation.
Experientia 1996;52(10-11):1008-17.
1996: Keping Xie; Suyun Huang; Y Wang; P J Beltran; SH Juang; Zhongyun Dong; J C Reed; Timothy J McDonnell; David J McConkey; Isaiah J Fidler
Bcl-2 protects cells from cytokine-induced nitric-oxide-dependent apoptosis.
Cancer immunology, immunotherapy : CII 1996;43(2):109-15.
1996: Jack A Roth; Dao Nguyen; DD Lawrence; Bonnie L Kemp; C H Carrasco; David Ferson; Waun Ki Hong; Ritsuko Komaki; J Jack Lee; Jonathan C Nesbitt; Katherine M W Pisters; Joe B Putnam; RA Schea; Dong M Shin; Garrett L Walsh; M M Dolormente; C I Han; F D Martin; Nancy Yen; K Xu; L C Stephens; Timothy J McDonnell; T Mukhopadhyay; D Cai
Retrovirus-mediated wild-type p53 gene transfer to tumors of patients with lung cancer.
Nature medicine 1996;2(9):985-91.
1996: K Jagannadha Sastry; M C Marin; Pramod N Nehete; K McConnell; Adel K El-Naggar; Timothy J McDonnell
Expression of human immunodeficiency virus type I tat results in down-regulation of bcl-2 and induction of apoptosis in hematopoietic cells.
Oncogene 1996;13(3):487-93.
1996: M C Marin; A Fernandez; R J Bick; Shawn Brisbay; L Maximilian Buja; M Snuggs; David J McConkey; Andrew C von Eschenbach; M J Keating; Timothy J McDonnell
Apoptosis suppression by bcl-2 is correlated with the regulation of nuclear and cytosolic Ca2+.
Oncogene 1996;12(11):2259-66.
1996: KD Steck; Timothy J McDonnell; Nour Sneige; Adel El-Naggar
Flow cytometric analysis of apoptosis and bcl-2 in primary breast carcinomas: clinical and biological implications.
Cytometry 1996;24(2):116-22.
1996: David J McConkey; Joya Chandra; S Wright; William Plunkett; Timothy J McDonnell; J C Reed; Michael Keating
Apoptosis sensitivity in chronic lymphocytic leukemia is determined by endogenous endonuclease content and relative expression of BCL-2 and BAX.
Journal of immunology (Baltimore, Md. : 1950) 1996;156(7):2624-30.
1996: Y Sanchez; Mercedes Lovell; M C Marin; P E Wong; M E Wolf-Ledbetter; Timothy J McDonnell; Ann McNeill Killary
Tumor suppression and apoptosis of human prostate carcinoma mediated by a genetic locus within human chromosome 10pter-q11.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(6):2551-6.
1996: LE Robertson; William Plunkett; K McConnell; Michael J Keating; Timothy J McDonnell
Bcl-2 expression in chronic lymphocytic leukemia and its correlation with the induction of apoptosis and clinical outcome.
Leukemia 1996;10(3):456-9.
1996: Candelaria Gomez-Manzano; Juan Fueyo; Athanassios P Kyritsis; PA Steck; Jack A Roth; Timothy J McDonnell; KD Steck; Victor Levin; W K Alfred Yung
Adenovirus-mediated transfer of the p53 gene produces rapid and generalized death of human glioma cells via apoptosis.
Cancer research 1996;56(4):694-9.
1995: S M Hewitt; S Hamada; Timothy J McDonnell; Frank J Rauscher; Grady F Saunders
Regulation of the proto-oncogenes bcl-2 and c-myc by the Wilms' tumor suppressor gene WT1.
Cancer research 1995;55(22):5386-9.
1995: B Hsu; M C Marin; Timothy J McDonnell
Cell death regulation during multistep lymphomagenesis.
Cancer letters 1995;94(1):17-23.
1995: Ta-Jen Liu; Adel K El-Naggar; Timothy J McDonnell; KD Steck; Mary Wang; D L Taylor; Gary L Clayman
Apoptosis induction mediated by wild-type p53 adenoviral gene transfer in squamous cell carcinoma of the head and neck.
Cancer research 1995;55(14):3117-22.
1995: Shi-Ming Tu; K McConnell; M C Marin; M L Campbell; A Fernandez; Andrew C von Eschenbach; Timothy J McDonnell
Combination adriamycin and suramin induces apoptosis in bcl-2 expressing prostate carcinoma cells.
Cancer letters 1995;93(2):147-55.
1995: B Hsu; M C Marin; Adel K El-Naggar; L Clifton Stephens; Shawn Brisbay; Timothy J McDonnell
Evidence that c-myc mediated apoptosis does not require wild-type p53 during lymphomagenesis.
Oncogene 1995;11(1):175-9.
1995: KD Steck; Timothy J McDonnell; Adel K El-Naggar
Flow cytometric analysis of apoptosis and bcl-2 in human solid neoplasms.
Cytometry 1995;20(2):154-61.
1995: J Rodriguez-Villanueva; MI Colome; Shawn Brisbay; Timothy J McDonnell
The expression and localization of bcl-2 protein in normal skin and in non-melanoma skin cancers.
Pathology, research and practice 1995;191(5):391-8.
1995: M C Marin; B Hsu; L Clifton Stephens; Shawn Brisbay; Timothy J McDonnell
The functional basis of c-myc and bcl-2 complementation during multistep lymphomagenesis in vivo.
Experimental cell research 1995;217(2):240-7.
1995: J Rodríguez-Villanueva; Timothy J McDonnell
Induction of apoptotic cell death in non-melanoma skin cancer by interferon-alpha.
International journal of cancer. Journal international du cancer 1995;61(1):110-4.
1995: A Fernandez; L J Fosdick; M C Marin; C Diaz; Timothy J McDonnell; Honnavara N Ananthaswamy; David J McConkey
Differential regulation of endogenous endonuclease activation in isolated murine fibroblast nuclei by ras and bcl-2.
Oncogene 1995;10(4):769-74.
1995: Timothy J McDonnell; R E Meyn; LE Robertson
Implications of apoptotic cell death regulation in cancer therapy.
Seminars in cancer biology 1995;6(1):53-60.
1994: M C Marin; B Hsu; Raymond E Meyn; Lawrence A Donehower; Adel K El-Naggar; Timothy J McDonnell
Evidence that p53 and bcl-2 are regulators of a common cell death pathway important for in vivo lymphomagenesis.
Oncogene 1994;9(11):3107-12.
1994: Dawn Chandler; Adel K El-Naggar; Shawn Brisbay; R W Redline; Timothy J McDonnell
Apoptosis and expression of the bcl-2 proto-oncogene in the fetal and adult human kidney: evidence for the contribution of bcl-2 expression to renal carcinogenesis.
Human pathology 1994;25(8):789-96.
1994: A Fernandez; M C Marin; Timothy J McDonnell; Honnavara N Ananthaswamy
Differential sensitivity of normal and Ha-ras-transformed C3H mouse embryo fibroblasts to tumor necrosis factor: induction of bcl-2, c-myc, and manganese superoxide dismutase in resistant cells.
Oncogene 1994;9(7):2009-17.
1993: Timothy J McDonnell; M C Marin; B Hsu; Shawn Brisbay; K McConnell; Shi-Ming Tu; M L Campbell; J Rodriguez-Villanueva
The bcl-2 oncogene: apoptosis and neoplasia.
Radiation research 1993;136(3):307-12.
1993: Timothy J McDonnell
Cell division versus cell death: a functional model of multistep neoplasia.
Molecular carcinogenesis 1993;8(4):209-13.
1992: Timothy J McDonnell; Patricia Troncoso; Shawn Brisbay; C Logothetis; Leland W K Chung; Jer-Tsong Hsieh; Shi-Ming Tu; M L Campbell
Expression of the protooncogene bcl-2 in the prostate and its association with emergence of androgen-independent prostate cancer.
Cancer research 1992;52(24):6940-4.
1991: G Nuñez; David M Hockenbery; Timothy J McDonnell; C M Sorensen; Stanley J Korsmeyer
Bcl-2 maintains B cell memory.
Nature 1991;353(6339):71-3.
1991: Timothy J McDonnell; Stanley J Korsmeyer
Progression from lymphoid hyperplasia to high-grade malignant lymphoma in mice transgenic for the t(14; 18).
Nature 1991;349(6306):254-6.
1990: Timothy J McDonnell; Gabriel Nunez; F M Platt; D Hockenberry; L London; John P McKearn; Stanley J Korsmeyer
Deregulated Bcl-2-immunoglobulin transgene expands a resting but responsive immunoglobulin M and D-expressing B-cell population.
Molecular and cellular biology 1990;10(5):1901-7.
1990: Stanley J Korsmeyer; Timothy J McDonnell; G Nunez; David M Hockenbery; R Young
Bcl-2: B cell life, death and neoplasia.
Current topics in microbiology and immunology 1990;166():203-7.
1989: Timothy J McDonnell; N Deane; F M Platt; Gabriel Nunez; U Jaeger; John P McKearn; Stanley J Korsmeyer
bcl-2-immunoglobulin transgenic mice demonstrate extended B cell survival and follicular lymphoproliferation.
Cell 1989;57(1):79-88.
1987: J M Tate; Timothy J McDonnell; J C Oberpriller; J O Oberpriller
Isolation of cardiac myocytes from the adult newt, Notophthalmus viridescens. an electron microscopic and quantitative light microscopic analysis.
Tissue & cell 1987;19(4):577-85.
1984: Timothy J McDonnell; J O Oberpriller
The response of the atrium to direct mechanical wounding in the adult heart of the newt, Notophthalmus viridescens. An electron-microscopic and autoradiographic study.
Cell and tissue research 1984;235(3):583-92.
1983: Timothy J McDonnell; J O Oberpriller
The atrial proliferative response following partial ventricular amputation in the heart of the adult newt. A light and electron microscopic autoradiographic study.
Tissue & cell 1983;15(3):351-63.