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Alex McDougall

Research Profile

Physiology

Phenomena

Fertilization

Chemicals & Drugs

Anatomy

Concepts & Ideas

Living Beings

Mouse

Procedures

Microinjections

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Publications

TOP 3
Mark Levasseur; Michael Carroll; Keith T Jones; Alex McDougall
A novel mechanism controls the Ca2+ oscillations triggered by activation of ascidian eggs and has an absolute requirement for Cdk1 activity.
H Parry; Alex McDougall; Michael Whitaker
Endoplasmic reticulum generates calcium signalling microdomains around the nucleus and spindle in syncytial Drosophila embryos.
Hayden A Homer; Alex McDougall; Mark Levasseur; Alison P Murdoch; Mary Herbert
Mad2 is required for inhibiting securin and cyclin B degradation following spindle depolymerisation in meiosis I mouse oocytes.

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All Publications

2007: Mark Levasseur; Michael Carroll; Keith T Jones; Alex McDougall
A novel mechanism controls the Ca2+ oscillations triggered by activation of ascidian eggs and has an absolute requirement for Cdk1 activity.
Journal of cell science 2007;120(Pt 10):1763-71.
2006: H Parry; Alex McDougall; Michael Whitaker
Endoplasmic reticulum generates calcium signalling microdomains around the nucleus and spindle in syncytial Drosophila embryos.
Biochemical Society transactions 2006;34(Pt 3):385-8.
2005: Hayden A Homer; Alex McDougall; Mark Levasseur; Alison P Murdoch; Mary Herbert
Mad2 is required for inhibiting securin and cyclin B degradation following spindle depolymerisation in meiosis I mouse oocytes.
Reproduction (Cambridge, England) 2005;130(6):829-43.
2005: Huw Parry; Alex McDougall; Michael Whitaker
Microdomains bounded by endoplasmic reticulum segregate cell cycle calcium transients in syncytial Drosophila embryos.
The Journal of cell biology 2005;171(1):47-59.
2005: Hayden A Homer; Alex McDougall; Mark Levasseur; Alison P Murdoch; Mary Herbert
RNA interference in meiosis I human oocytes: towards an understanding of human aneuploidy.
Molecular human reproduction 2005;11(6):397-404.
2005: Hayden A Homer; Alex McDougall; Mark Levasseur; Mary Herbert
Restaging the spindle assembly checkpoint in female mammalian meiosis I.
Cell cycle (Georgetown, Tex.) 2005;4(5):650-3.
2005: Alex McDougall; David J Elliott; Neil Hunter
Pairing, connecting, exchanging, pausing and pulling chromosomes.
EMBO reports 2005;6(2):120-5.
2005: Hayden A Homer; Alex McDougall; Mark Levasseur; Katie Yallop; Alison P Murdoch; Mary Herbert
Mad2 prevents aneuploidy and premature proteolysis of cyclin B and securin during meiosis I in mouse oocytes.
Genes & development 2005;19(2):202-7.
2004: Louise A Hyslop; Victoria L Nixon; Mark Levasseur; Faye Chapman; Kazuyoshi Chiba; Alex McDougall; Julian P Venables; David J Elliott; Keith T Jones
Ca(2+)-promoted cyclin B1 degradation in mouse oocytes requires the establishment of a metaphase arrest.
Developmental biology 2004;269(1):206-19.
2003: Michael Carroll; Mark Levasseur; Chris Wood; Michael Whitaker; Keith T Jones; Alex McDougall
Exploring the mechanism of action of the sperm-triggered calcium-wave pacemaker in ascidian zygotes.
Journal of cell science 2003;116(Pt 24):4997-5004.
2003: Mary Herbert; Mark Levasseur; Hayden A Homer; Katie Yallop; Alison P Murdoch; Alex McDougall
Homologue disjunction in mouse oocytes requires proteolysis of securin and cyclin B1.
Nature cell biology 2003;5(11):1023-5.
2003: Mark Levasseur; Alex McDougall
Inositol 1,4,5-trisphosphate (IP3) responsiveness is regulated in a meiotic cell cycle dependent manner: implications for fertilization induced calcium signaling.
Cell cycle (Georgetown, Tex.) 2003;2(6):610-3.
2002: Victoria L Nixon; Mark Levasseur; Alex McDougall; Keith T Jones
Ca(2+) oscillations promote APC/C-dependent cyclin B1 degradation during metaphase arrest and completion of meiosis in fertilizing mouse eggs.
Current biology : CB 2002;12(9):746-50.
2001: L A Hyslop; Michael Carroll; Victoria L Nixon; Alex McDougall; Keith T Jones
Simultaneous measurement of intracellular nitric oxide and free calcium levels in chordate eggs demonstrates that nitric oxide has no role at fertilization.
Developmental biology 2001;234(1):216-30.
2000: Alex McDougall; Mark Levasseur; A J O'Sullivan; Keith T Jones
Cell cycle-dependent repetitive Ca(2+ )waves induced by a cytosolic sperm extract in mature ascidian eggs mimic those observed at fertilization.
Journal of cell science 2000;113 Pt 19():3453-62.
2000: Alex McDougall; J Shearer; Michael Whitaker
The initiation and propagation of the fertilization wave in sea urchin eggs.
Biology of the cell / under the auspices of the European Cell Biology Organization 2000;92(3-4):205-14.
2000: Victoria L Nixon; Alex McDougall; Keith T Jones
Ca2+ oscillations and the cell cycle at fertilisation of mammalian and ascidian eggs.
Biology of the cell / under the auspices of the European Cell Biology Organization 2000;92(3-4):187-96.
2000: Mark Levasseur; Alex McDougall
Sperm-induced calcium oscillations at fertilisation in ascidians are controlled by cyclin B1-dependent kinase activity.
Development (Cambridge, England) 2000;127(3):631-41.
1998: Alex McDougall; Mark Levasseur
Sperm-triggered calcium oscillations during meiosis in ascidian oocytes first pause, restart, then stop: correlations with cell cycle kinase activity.
Development (Cambridge, England) 1998;125(22):4451-9.