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Edith McGeer

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Moonhee Lee; Edith G McGeer; Jian-Ping Guo; Patrick L McGeer
Aurin tricarboxylic acid self-protects by inhibiting aberrant complement activation at the C3 convertase and C9 binding stages.
Claudia Schwab; Winnie Wong; Sheng Yu; Edith G McGeer; Patrick L McGeer
GAD65, GAD67, and GABAT immunostaining in human brain and apparent GAD65 loss in Alzheimer's disease.
Moonhee Lee; Edith G McGeer; Jian-Ping Guo; Claudia Schwab; Patrick L McGeer
Selective inhibition of the membrane attack complex of complement by low molecular weight components of the aurin tricarboxylic acid synthetic complex.

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All Publications

2013: Moonhee Lee; Edith G McGeer; Jian-Ping Guo; Patrick L McGeer
Aurin tricarboxylic acid self-protects by inhibiting aberrant complement activation at the C3 convertase and C9 binding stages.
Neurobiology of aging 2013;34(5):1451-61.
2013: Claudia Schwab; Winnie Wong; Sheng Yu; Edith G McGeer; Patrick L McGeer
GAD65, GAD67, and GABAT immunostaining in human brain and apparent GAD65 loss in Alzheimer's disease.
Journal of Alzheimer's disease : JAD 2013;33(4):1073-88.
2012: Moonhee Lee; Edith G McGeer; Jian-Ping Guo; Claudia Schwab; Patrick L McGeer
Selective inhibition of the membrane attack complex of complement by low molecular weight components of the aurin tricarboxylic acid synthetic complex.
Neurobiology of aging 2012;33(10):2237-46.
2011: Moonhee Lee; Edith G McGeer; Patrick L McGeer
Mechanisms of GABA release from human astrocytes.
Glia 2011;59(11):1600-11.
2011: Moonhee Lee; Edith G McGeer; Yunhee Kang; Kyoungho Suk; Patrick L McGeer
Neurotoxic factors released by stimulated human monocytes and THP-1 cells.
Brain research 2011;1400():99-111.
2011: Moonhee Lee; nattinee jantaratnotai; Edith G McGeer; James G McLarnon; Patrick L McGeer
Mg2+ ions reduce microglial and THP-1 cell neurotoxicity by inhibiting Ca2+ entry through purinergic channels.
Brain research 2011;1369():21-35.
2011: Patrick L McGeer; Edith G McGeer
History of innate immunity in neurodegenerative disorders.
Frontiers in pharmacology 2011;2():77.
2010: Moonhee Lee; Taesup Cho; nattinee jantaratnotai; Yu Tian Wang; Edith G McGeer; Patrick L McGeer
Depletion of GSH in glial cells induces neurotoxicity: relevance to aging and degenerative neurological diseases.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2010;24(7):2533-45.
2010: Moonhee Lee; Valerio Tazzari; Daniela Giustarini; Ranieri Rossi; Anna Sparatore; Piero Del Soldato; Edith G McGeer; Patrick L McGeer
Effects of hydrogen sulfide-releasing L-DOPA derivatives on glial activation: potential for treating Parkinson disease.
The Journal of biological chemistry 2010;285(23):17318-28.
2010: Edith G McGeer; Patrick L McGeer
Neuroinflammation in Alzheimer's disease and mild cognitive impairment: a field in its infancy.
Journal of Alzheimer's disease : JAD 2010;19(1):355-61.
2010: Moonhee Lee; Anna Sparatore; Piero Del Soldato; Edith G McGeer; Patrick L McGeer
Hydrogen sulfide-releasing NSAIDs attenuate neuroinflammation induced by microglial and astrocytic activation.
Glia 2010;58(1):103-13.
2009: Hong Qing; Yanyan Zhang; Yulin Deng; Edith G McGeer; Patrick L McGeer
Lrrk2 interaction with alpha-synuclein in diffuse Lewy body disease.
Biochemical and biophysical research communications 2009;390(4):1229-34.
2009: Moonhee Lee; Claudia Schwab; Sheng Yu; Edith G McGeer; Patrick L McGeer
Astrocytes produce the antiinflammatory and neuroprotective agent hydrogen sulfide.
Neurobiology of aging 2009;30(10):1523-34.
2009: Hong Qing; Winnie Wong; Edith G McGeer; Patrick L McGeer
Lrrk2 phosphorylates alpha synuclein at serine 129: Parkinson disease implications.
Biochemical and biophysical research communications 2009;387(1):149-52.
2008: Judith Miklossy; John C Steele; Sheng Yu; Sherman McCall; Glenn Sandberg; Edith G McGeer; Patrick L McGeer
Enduring involvement of tau, beta-amyloid, alpha-synuclein, ubiquitin and TDP-43 pathology in the amyotrophic lateral sclerosis/parkinsonism-dementia complex of Guam (ALS/PDC).
Acta neuropathologica 2008;116(6):625-37.
2008: Patrick L McGeer; Edith G McGeer
The alpha-synuclein burden hypothesis of Parkinson disease and its relationship to Alzheimer disease.
Experimental neurology 2008;212(2):235-8.
2008: Andis Klegeris; Steven Pelech; Benoit I Giasson; John Maguire; Hong Zhang; Edith G McGeer; Patrick L McGeer
Alpha-synuclein activates stress signaling protein kinases in THP-1 cells and microglia.
Neurobiology of aging 2008;29(5):739-52.
2008: Patrick L McGeer; Edith G McGeer
Glial reactions in Parkinson's disease.
Movement disorders : official journal of the Movement Disorder Society 2008;23(4):474-83.
2007: Judith Miklossy; Hong Qing; Jian-Ping Guo; Sheng Yu; Zbigniew K Wszolek; Donald B Calne; Edith G McGeer; Patrick L McGeer
Lrrk2 and chronic inflammation are linked to pallido-ponto-nigral degeneration caused by the N279K tau mutation.
Acta neuropathologica 2007;114(3):243-54.
2007: Andis Klegeris; Edith G McGeer; Patrick L McGeer
Therapeutic approaches to inflammation in neurodegenerative disease.
Current opinion in neurology 2007;20(3):351-7.
2007: Patrick L McGeer; Edith G McGeer
NSAIDs and Alzheimer disease: epidemiological, animal model and clinical studies.
Neurobiology of aging 2007;28(5):639-47.
2007: Edith G McGeer; Patrick L McGeer
The role of anti-inflammatory agents in Parkinson's disease.
CNS drugs 2007;21(10):789-97.
2006: Judith Miklossy; Tetsuaki Arai; Jian-Ping Guo; Andis Klegeris; Sheng Yu; Edith G McGeer; Patrick L McGeer
LRRK2 expression in normal and pathologic human brain and in human cell lines.
Journal of neuropathology and experimental neurology 2006;65(10):953-63.
2006: Judith Miklossy; D D Doudet; Claudia Schwab; S Yu; Edith G McGeer; Patrick L McGeer
Role of ICAM-1 in persisting inflammation in Parkinson disease and MPTP monkeys.
Experimental neurology 2006;197(2):275-83.
2006: Patrick L McGeer; Joseph Rogers; Edith G McGeer
Inflammation, anti-inflammatory agents and Alzheimer disease: the last 12 years.
Journal of Alzheimer's disease : JAD 2006;9(3 Suppl):271-6.
2005: Edith G McGeer; Andis Klegeris; Patrick L McGeer
Inflammation, the complement system and the diseases of aging.
Neurobiology of aging 2005;26 Suppl 1():94-7.
2005: Edith G McGeer; Patrick L McGeer
Abeta immunotherapy and other means to remove amyloid.
Current drug targets. CNS and neurological disorders 2005;4(5):569-73.
2005: Edith G McGeer; Patrick L McGeer
Pharmacologic approaches to the treatment of amyotrophic lateral sclerosis.
BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy 2005;19(1):31-7.
2004: Patrick L McGeer; Edith G McGeer
Inflammation and the degenerative diseases of aging.
Annals of the New York Academy of Sciences 2004;1035():104-16.
2004: Patrick L McGeer; Edith G McGeer
Immunotherapy for Alzheimer's disease.
Science of aging knowledge environment : SAGE KE 2004;2004(27):pe29.
2004: Christopher J Bissonnette; Andis Klegeris; Patrick L McGeer; Edith G McGeer
Interleukin 1alpha and interleukin 6 protect human neuronal SH-SY5Y cells from oxidative damage.
Neuroscience letters 2004;361(1-3):40-3.
2004: Patrick L McGeer; Edith G McGeer
Inflammation and neurodegeneration in Parkinson's disease.
Parkinsonism & related disorders 2004;10 Suppl 1():S3-7.
2003: Edith G McGeer; Patrick L McGeer
Inflammatory processes in Alzheimer's disease.
Progress in neuro-psychopharmacology & biological psychiatry 2003;27(5):741-9.
2003: Edith G McGeer; Patrick L McGeer
Clinically tested drugs for Alzheimer's disease.
Expert opinion on investigational drugs 2003;12(7):1143-51.
2003: Patrick L McGeer; Edith G McGeer
Is there a future for vaccination as a treatment for Alzheimer's disease?
Neurobiology of aging 2003;24(3):391-5.
2002: Patrick L McGeer; Edith G McGeer
Local neuroinflammation and the progression of Alzheimer's disease.
Journal of neurovirology 2002;8(6):529-38.
2002: Patrick L McGeer; Edith G McGeer
The possible role of complement activation in Alzheimer disease.
Trends in molecular medicine 2002;8(11):519-23.
2002: Patrick L McGeer; Edith G McGeer
Inflammatory processes in amyotrophic lateral sclerosis.
Muscle & nerve 2002;26(4):459-70.
2002: Patrick L McGeer; Edith G McGeer
Innate immunity, local inflammation, and degenerative disease.
Science of aging knowledge environment : SAGE KE 2002;2002(29):re3.
2002: Patrick L McGeer; Edith G McGeer; Koji Yasojima
Expression of COX-1 and COX-2 mRNAs in atherosclerotic plaques.
Experimental gerontology 2002;37(7):925-9.
2002: Patrick L McGeer; Koji Yasojima; Edith G McGeer
Association of interleukin-1 beta polymorphisms with idiopathic Parkinson's disease.
Neuroscience letters 2002;326(1):67-9.
2001: Patrick L McGeer; Edith G McGeer; Koji Yasojima
Cardiovascular events and COX-2 inhibitors.
JAMA : the journal of the American Medical Association 2001;286(22):2810; author reply 2811-2.
2001: Koji Yasojima; Edith G McGeer; Patrick L McGeer
High stability of mRNAs postmortem and protocols for their assessment by RT-PCR.
Brain research. Brain research protocols 2001;8(3):212-8.
2001: Koji Yasojima; Edith G McGeer; Patrick L McGeer
Relationship between beta amyloid peptide generating molecules and neprilysin in Alzheimer disease and normal brain.
Brain research 2001;919(1):115-21.
2001: Edith G McGeer; Koji Yasojima; Claudia Schwab; Patrick L McGeer
The pentraxins: possible role in Alzheimer's disease and other innate inflammatory diseases.
Neurobiology of aging 2001;22(6):843-8.
2001: Patrick L McGeer; Edith G McGeer
Inflammation, autotoxicity and Alzheimer disease.
Neurobiology of aging 2001;22(6):799-809.
2001: Patrick L McGeer; Edith G McGeer
Polymorphisms in inflammatory genes and the risk of Alzheimer disease.
Archives of neurology 2001;58(11):1790-2.
2001: Koji Yasojima; W W Tourtellotte; Edith G McGeer; Patrick L McGeer
Marked increase in cyclooxygenase-2 in ALS spinal cord: implications for therapy.
Neurology 2001;57(6):952-6.
2001: Koji Yasojima; Edith G McGeer; Patrick L McGeer
3-hydroxy-3-methylglutaryl-coenzyme A reductase mRNA in Alzheimer and control brain.
Neuroreport 2001;12(13):2935-8.
2001: Edith G McGeer; Patrick L McGeer
Chronic inflammation in Alzheimer's disease offers therapeutic opportunities.
Expert review of neurotherapeutics 2001;1(1):53-60.
2001: Koji Yasojima; Claudia Schwab; Edith G McGeer; Patrick L McGeer
Complement components, but not complement inhibitors, are upregulated in atherosclerotic plaques.
Arteriosclerosis, thrombosis, and vascular biology 2001;21(7):1214-9.
2001: Edith G McGeer; Patrick L McGeer
Innate immunity in Alzheimer's disease: a model for local inflammatory reactions.
Molecular interventions 2001;1(1):22-9.
2001: Koji Yasojima; Claudia Schwab; Edith G McGeer; Patrick L McGeer
Generation of C-reactive protein and complement components in atherosclerotic plaques.
The American journal of pathology 2001;158(3):1039-51.
2001: Koji Yasojima; Haruhiko Akiyama; Edith G McGeer; Patrick L McGeer
Reduced neprilysin in high plaque areas of Alzheimer brain: a possible relationship to deficient degradation of beta-amyloid peptide.
Neuroscience letters 2001;297(2):97-100.
2001: Patrick L McGeer; Koji Yasojima; Edith G McGeer
Inflammation in Parkinson's disease.
Advances in neurology 2001;86():83-9.
2000: Koji Yasojima; Claudia Schwab; Edith G McGeer; Patrick L McGeer
Human neurons generate C-reactive protein and amyloid P: upregulation in Alzheimer's disease.
Brain research 2000;887(1):80-9.
2000: Doris J Doudet; James E Holden; Salma Jivan; Edith G McGeer; Richard J Wyatt
In vivo PET studies of the dopamine D2 receptors in rhesus monkeys with long-term MPTP-induced parkinsonism.
Synapse (New York, N.Y.) 2000;38(2):105-13.
2000: EJ Tanhehco; Koji Yasojima; Patrick L McGeer; Edith G McGeer; Benedict R Lucchesi
Preconditioning reduces myocardial complement gene expression in vivo.
American journal of physiology. Heart and circulatory physiology 2000;279(3):H1157-65.
2000: JM van Kampen; Edith G McGeer; A Jon Stoessl
Dopamine transporter function assessed by antisense knockdown in the rat: protection from dopamine neurotoxicity.
Synapse (New York, N.Y.) 2000;37(3):171-8.
2000: Patrick L McGeer; Edith G McGeer
Autotoxicity and Alzheimer disease.
Archives of neurology 2000;57(6):789-90.
2000: Koji Yasojima; Jeffrey Kuret; AJ DeMaggio; Edith G McGeer; Patrick L McGeer
Casein kinase 1 delta mRNA is upregulated in Alzheimer disease brain.
Brain research 2000;865(1):116-20.
2000: Andis Klegeris; Edith G McGeer; Patrick L McGeer
Inhibitory action of 1-(2-chlorophenyl)-N-methyl-N-(1-methylpropyl)-3-isoquinolinecarboxam ide (PK 11195) on some mononuclear phagocyte functions.
Biochemical pharmacology 2000;59(10):1305-14.
2000: Patrick L McGeer; Edith G McGeer; Koji Yasojima
Alzheimer disease and neuroinflammation.
Journal of neural transmission. Supplementum 2000;59():53-7.
1999: J Douglas Waterfield; Edith G McGeer; Patrick L McGeer
The peripheral benzodiazepine receptor ligand PK 11195 inhibits arthritis in the MRL-lpr mouse model.
Rheumatology (Oxford, England) 1999;38(11):1068-73.
1999: Edith G McGeer; Patrick L McGeer
Brain inflammation in Alzheimer disease and the therapeutic implications.
Current pharmaceutical design 1999;5(10):821-36.
1999: Koji Yasojima; Edith G McGeer; Patrick L McGeer
Complement regulators C1 inhibitor and CD59 do not significantly inhibit complement activation in Alzheimer disease.
Brain research 1999;833(2):297-301.
1999: Koji Yasojima; Edith G McGeer; Patrick L McGeer
Tangled areas of Alzheimer brain have upregulated levels of exon 10 containing tau mRNA.
Brain research 1999;831(1-2):301-5.
1999: Koji Yasojima; Claudia Schwab; Edith G McGeer; Patrick L McGeer
Distribution of cyclooxygenase-1 and cyclooxygenase-2 mRNAs and proteins in human brain and peripheral organs.
Brain research 1999;830(2):226-36.
1999: Patrick L McGeer; Edith G McGeer
Inflammation of the brain in Alzheimer's disease: implications for therapy.
Journal of leukocyte biology 1999;65(4):409-15.
1999: Koji Yasojima; Claudia Schwab; Edith G McGeer; Patrick L McGeer
Up-regulated production and activation of the complement system in Alzheimer's disease brain.
The American journal of pathology 1999;154(3):927-36.
1999: Doris J Doudet; GL Chan; Salma Jivan; Onofre T DeJesus; Edith G McGeer; C English; Thomas J Ruth; James E Holden
Evaluation of dopaminergic presynaptic integrity: 6-[18F]fluoro-L-dopa versus 6-[18F]fluoro-L-m-tyrosine.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1999;19(3):278-87.
1998: Claudia Schwab; Haruhiko Akiyama; Edith G McGeer; Patrick L McGeer
Extracellular neurofibrillary tangles are immunopositive for the 40 carboxy-terminal sequence of beta-amyloid protein.
Journal of neuropathology and experimental neurology 1998;57(12):1131-7.
1998: Koji Yasojima; Claudia Schwab; Edith G McGeer; Patrick L McGeer
Human heart generates complement proteins that are upregulated and activated after myocardial infarction.
Circulation research 1998;83(8):860-9.
1998: Akinori Matsuo; Ichiro Akiguchi; G C Lee; Edith G McGeer; Patrick L McGeer; Jun Kimura
Myelin degeneration in multiple system atrophy detected by unique antibodies.
The American journal of pathology 1998;153(3):735-44.
1998: K Takami; Akinori Matsuo; K Terai; Douglas G. Walker; Edith G McGeer; Patrick L McGeer
Fibroblast growth factor receptor-1 expression in the cortex and hippocampus in Alzheimer's disease.
Brain research 1998;802(1-2):89-97.
1998: Edith G McGeer; Patrick L McGeer
The importance of inflammatory mechanisms in Alzheimer disease.
Experimental gerontology 1998;33(5):371-8.
1998: Doris J Doudet; GL Chan; James E Holden; Edith G McGeer; T A Aigner; Richard J Wyatt; Thomas J Ruth
6-[18F]Fluoro-L-DOPA PET studies of the turnover of dopamine in MPTP-induced parkinsonism in monkeys.
Synapse (New York, N.Y.) 1998;29(3):225-32.
1998: Douglas G. Walker; K Terai; Akinori Matsuo; Thomas Beach; Edith G McGeer; Patrick L McGeer
Immunohistochemical analyses of fibroblast growth factor receptor-1 in the human substantia nigra. Comparison between normal and Parkinson's disease cases.
Brain research 1998;794(2):181-7.
1998: Edith G McGeer; Patrick L McGeer
The future use of complement inhibitors for the treatment of neurological diseases.
Drugs 1998;55(6):739-46.
1998: Douglas G. Walker; Thomas Beach; R Xu; Jack Lile; K D Beck; Edith G McGeer; Patrick L McGeer
Expression of the proto-oncogene Ret, a component of the GDNF receptor complex, persists in human substantia nigra neurons in Parkinson's disease.
Brain research 1998;792(2):207-17.
1998: Patrick L McGeer; Edith G McGeer
Mechanisms of cell death in Alzheimer disease--immunopathology.
Journal of neural transmission. Supplementum 1998;54():159-66.
1998: Patrick L McGeer; Edith G McGeer
Glial cell reactions in neurodegenerative diseases: pathophysiology and therapeutic interventions.
Alzheimer disease and associated disorders 1998;12 Suppl 2():S1-6.
1998: Patrick L McGeer; T Kawamata; Edith G McGeer
Localization and possible functions of presenilins in brain.
Reviews in the neurosciences 1998;9(1):1-15.
1997: Edith G McGeer; Patrick L McGeer
The role of the immune system in neurodegenerative disorders.
Movement disorders : official journal of the Movement Disorder Society 1997;12(6):855-8.
1997: Yong Shen; Rena Li; Edith G McGeer; Patrick L McGeer
Neuronal expression of mRNAs for complement proteins of the classical pathway in Alzheimer brain.
Brain research 1997;769(2):391-5.
1997: K Terai; Douglas G. Walker; Edith G McGeer; Patrick L McGeer
Neurons express proteins of the classical complement pathway in Alzheimer disease.
Brain research 1997;769(2):385-90.
1997: Patrick L McGeer; Claudia Schwab; Edith G McGeer; R L Haddock; John C Steele
Familial nature and continuing morbidity of the amyotrophic lateral sclerosis-parkinsonism dementia complex of Guam.
Neurology 1997;49(2):400-9.
1997: Akinori Matsuo; G C Lee; K Terai; K Takami; W F Hickey; Edith G McGeer; Patrick L McGeer
Unmasking of an unusual myelin basic protein epitope during the process of myelin degeneration in humans: a potential mechanism for the generation of autoantigens.
The American journal of pathology 1997;150(4):1253-66.
1997: Patrick L McGeer; Douglas G. Walker; Robert E Pitas; Robert W Mahley; Edith G McGeer
Apolipoprotein E4 (ApoE4) but not ApoE3 or ApoE2 potentiates beta-amyloid protein activation of complement in vitro.
Brain research 1997;749(1):135-8.
1997: Claudia Schwab; John C Steele; Edith G McGeer; Patrick L McGeer
Amyloid P immunoreactivity precedes C4d deposition on extracellular neurofibrillary tangles.
Acta neuropathologica 1997;93(1):87-92.
1996: K Terai; Akinori Matsuo; Edith G McGeer; Patrick L McGeer
Enhancement of immunoreactivity for NF-kappa B in human cerebral infarctions.
Brain research 1996;739(1-2):343-9.
1996: Patrick L McGeer; Michael Schulzer; Edith G McGeer
Arthritis and anti-inflammatory agents as possible protective factors for Alzheimer's disease: a review of 17 epidemiologic studies.
Neurology 1996;47(2):425-32.
1996: Osamu Yasuhara; Claudia Schwab; Akinori Matsuo; Seung Kim; John C Steele; Ichiro Akiguchi; J Kimura; Edith G McGeer; Patrick L McGeer
Midkine-like immunoreactivity in extracellular neurofibrillary tangles in brains of patients with parkinsonism-dementia complex of Guam.
Neuroscience letters 1996;205(2):107-10.
1996: Patrick L McGeer; Edith G McGeer
Anti-inflammatory drugs in the fight against Alzheimer's disease.
Annals of the New York Academy of Sciences 1996;777():213-20.
1995: Patrick L McGeer; Edith G McGeer
The inflammatory response system of brain: implications for therapy of Alzheimer and other neurodegenerative diseases.
Brain research. Brain research reviews 1995;21(2):195-218.
1995: Douglas G. Walker; Osamu Yasuhara; P A Patston; Edith G McGeer; Patrick L McGeer
Complement C1 inhibitor is produced by brain tissue and is cleaved in Alzheimer disease.
Brain research 1995;675(1-2):75-82.
1995: Claudia Schwab; John C Steele; Haruhiko Akiyama; Edith G McGeer; Patrick L McGeer
Relationship of amyloid beta/A4 protein to the neurofibrillary tangles in Guamanian parkinsonism-dementia.
Acta neuropathologica 1995;90(3):287-98.
1995: Osamu Yasuhara; Akinori Matsuo; I Tooyama; H Kimura; Edith G McGeer; Patrick L McGeer
Pick's disease immunohistochemistry: new alterations and Alzheimer's disease comparisons.
Acta neuropathologica 1995;89(4):322-30.
1994: Osamu Yasuhara; Yoshinari Aimi; Tatsuo Yamada; Akinori Matsuo; Edith G McGeer; Patrick L McGeer
Clusterin as a marker for ischaemic Purkinje cells in human brain.
Neurodegeneration : a journal for neurodegenerative disorders, neuroprotection, and neuroregeneration 1994;3(4):325-9.
1994: Patrick L McGeer; Andis Klegeris; Douglas G. Walker; Osamu Yasuhara; Edith G McGeer
Pathological proteins in senile plaques.
The Tohoku journal of experimental medicine 1994;174(3):269-77.
1994: I Tooyama; Edith G McGeer; T Kawamata; H Kimura; Patrick L McGeer
Retention of basic fibroblast growth factor immunoreactivity in dopaminergic neurons of the substantia nigra during normal aging in humans contrasts with loss in Parkinson's disease.
Brain research 1994;656(1):165-8.
1994: Osamu Yasuhara; Yoshinari Aimi; Edith G McGeer; Patrick L McGeer
Expression of the complement membrane attack complex and its inhibitors in Pick disease brain.
Brain research 1994;652(2):346-9.
1994: Osamu Yasuhara; T Kawamata; Yoshinari Aimi; Edith G McGeer; Patrick L McGeer
Two types of dystrophic neurites in senile plaques of Alzheimer disease and elderly non-demented cases.
Neuroscience letters 1994;171(1-2):73-6.
1994: Osamu Yasuhara; Yoshinari Aimi; Edith G McGeer; Patrick L McGeer
Accumulation of amyloid precursor protein in brain lesions of patients with Pick disease.
Neuroscience letters 1994;171(1-2):63-6.
1994: Patrick L McGeer; Douglas G. Walker; Haruhiko Akiyama; Osamu Yasuhara; Edith G McGeer
Involvement of microglia in Alzheimer's disease.
Neuropathology and applied neurobiology 1994;20(2):191-2.
1994: Osamu Yasuhara; T Kawamata; Yoshinari Aimi; Edith G McGeer; Patrick L McGeer
Expression of chromogranin A in lesions in the central nervous system from patients with neurological diseases.
Neuroscience letters 1994;170(1):13-6.
1994: Haruhiko Akiyama; K Ikeda; M Katoh; Edith G McGeer; Patrick L McGeer
Expression of MRP14, 27E10, interferon-alpha and leukocyte common antigen by reactive microglia in postmortem human brain tissue.
Journal of neuroimmunology 1994;50(2):195-201.
1994: Tatsuo Yamada; H Tsubouchi; Y Daikuhara; M Prat; paolo comoglio; Patrick L McGeer; Edith G McGeer
Immunohistochemistry with antibodies to hepatocyte growth factor and its receptor protein (c-MET) in human brain tissues.
Brain research 1994;637(1-2):308-12.
1994: Osamu Yasuhara; Haruhiko Akiyama; Edith G McGeer; Patrick L McGeer
Immunohistochemical localization of hyaluronic acid in rat and human brain.
Brain research 1994;635(1-2):269-82.
1994: Haruhiko Akiyama; I Tooyama; H Kondo; K Ikeda; H Kimura; Edith G McGeer; Patrick L McGeer
Early response of brain resident microglia to kainic acid-induced hippocampal lesions.
Brain research 1994;635(1-2):257-68.
1994: I Moroo; Tatsuo Yamada; Hideichi Makino; I Tooyama; Patrick L McGeer; Edith G McGeer; Keizo Hirayama
Loss of insulin receptor immunoreactivity from the substantia nigra pars compacta neurons in Parkinson's disease.
Acta neuropathologica 1994;87(4):343-8.
1994: Patrick L McGeer; Joseph Rogers; Edith G McGeer
Neuroimmune mechanisms in Alzheimer disease pathogenesis.
Alzheimer disease and associated disorders 1994;8(3):149-58.
1993: B D Pate; T Kawamata; Tatsuo Yamada; Edith G McGeer; K A Hewitt; BJ Snow; Thomas J Ruth; Donald B Calne
Correlation of striatal fluorodopa uptake in the MPTP monkey with dopaminergic indices.
Annals of neurology 1993;34(3):331-8.
1993: BJ Snow; I Tooyama; Edith G McGeer; Tatsuo Yamada; Donald B Calne; H Takahashi; H Kimura
Human positron emission tomographic [18F]fluorodopa studies correlate with dopamine cell counts and levels.
Annals of neurology 1993;34(3):324-30.
1993: I Tooyama; H P Kremer; Michael R Hayden; H Kimura; Edith G McGeer; Patrick L McGeer
Acidic and basic fibroblast growth factor-like immunoreactivity in the striatum and midbrain in Huntington's disease.
Brain research 1993;610(1):1-7.
1993: Edith G McGeer; B Kremer; Michael R Hayden
Monoamines and their metabolites in Huntington's disease brain: evidence for decreased catechol-O-methyltransferase activity.
Biological psychiatry 1993;33(7):551-3.
1993: I Tooyama; T Kawamata; Douglas G. Walker; Tatsuo Yamada; K Hanai; H Kimura; M Iwane; K Igarashi; Edith G McGeer; Patrick L McGeer
Loss of basic fibroblast growth factor in substantia nigra neurons in Parkinson's disease.
Neurology 1993;43(2):372-6.
1993: K Mizukawa; Edith G McGeer; Patrick L McGeer
Autoradiographic study on dopamine uptake sites and their correlation with dopamine levels and their striata from patients with Parkinson disease, Alzheimer disease, and neurologically normal controls.
Molecular and chemical neuropathology / sponsored by the International Society for Neurochemistry and the World Federation of Neurology and research groups on neurochemistry and cerebrospinal fluid 1993;18(1-2):133-44.
1993: Patrick L McGeer; T Kawamata; Douglas G. Walker; Haruhiko Akiyama; I Tooyama; Edith G McGeer
Microglia in degenerative neurological disease.
Glia 1993;7(1):84-92.
1993: Patrick L McGeer; Edith G McGeer
Neurotransmitters and their receptors in the basal ganglia.
Advances in neurology 1993;60():93-101.
1993: Tatsuo Yamada; Donald B Calne; Haruhiko Akiyama; Edith G McGeer; Patrick L McGeer
Further observations on Tau-positive glia in the brains with progressive supranuclear palsy.
Acta neuropathologica 1993;85(3):308-15.
1992: Edith G McGeer; E A Singh; Patrick L McGeer
Apparent anterograde transport of basic fibroblast growth factor in the rat nigrostriatal dopamine system.
Neuroscience letters 1992;148(1-2):31-3.
1992: I Tooyama; Douglas G. Walker; Tatsuo Yamada; K Hanai; H Kimura; Edith G McGeer; Patrick L McGeer
High molecular weight basic fibroblast growth factor-like protein is localized to a subpopulation of mesencephalic dopaminergic neurons in the rat brain.
Brain research 1992;593(2):274-80.
1992: K Shigematsu; Patrick L McGeer; Edith G McGeer
Localization of amyloid precursor protein in selective postsynaptic densities of rat cortical neurons.
Brain research 1992;592(1-2):353-7.
1992: P T Wong; Patrick L McGeer; Edith G McGeer
Decreased prostaglandin synthesis in postmortem cerebral cortex from patients with Alzheimer's disease.
Neurochemistry international 1992;21(2):197-202.
1992: Thomas Beach; Edith G McGeer
Cholinergic fiber loss occurs in the absence of synaptophysin depletion in Alzheimer's disease primary visual cortex.
Neuroscience letters 1992;142(2):253-6.
1992: Patrick L McGeer; Edith G McGeer
Complement proteins and complement inhibitors in Alzheimer's disease.
Research in immunology 1992;143(6):621-4.
1992: K Shigematsu; Patrick L McGeer; Douglas G. Walker; T Ishii; Edith G McGeer
Reactive microglia/macrophages phagocytose amyloid precursor protein produced by neurons following neural damage.
Journal of neuroscience research 1992;31(3):443-53.
1992: Tatsuo Yamada; Patrick L McGeer; Edith G McGeer
Appearance of paired nucleated, Tau-positive glia in patients with progressive supranuclear palsy brain tissue.
Neuroscience letters 1992;135(1):99-102.
1992: Tatsuo Yamada; Patrick L McGeer; Edith G McGeer
Lewy bodies in Parkinson's disease are recognized by antibodies to complement proteins.
Acta neuropathologica 1992;84(1):100-4.
1992: Thomas Beach; Edith G McGeer
Senile plaques, amyloid beta-protein, and acetylcholinesterase fibres: laminar distributions in Alzheimer's disease striate cortex.
Acta neuropathologica 1992;83(3):292-9.
1992: Barry Boyes; Douglas G. Walker; Patrick L McGeer; Edith G McGeer
Identification and characterization of a large human brain gene whose expression is increased in Alzheimer disease.
Brain research. Molecular brain research 1992;12(1-3):47-57.
1992: Tatsuo Yamada; Patrick L McGeer; Edith G McGeer
Some immunohistochemical features of argyrophilic grain dementia with normal cortical choline acetyltransferase levels but extensive subcortical pathology and markedly reduced dopamine.
Journal of geriatric psychiatry and neurology 1992;5(1):3-13.
1991: R W Parks; D L Long; D S Levine; D J Crockett; Edith G McGeer; Patrick L McGeer; I E Dalton; R F Zec; R E Becker; Kerry L Coburn
Parallel distributed processing and neural networks: origins, methodology and cognitive functions.
The International journal of neuroscience 1991;60(3-4):195-214.
1991: John R O'Kusky; Barry Boyes; Douglas G. Walker; Edith G McGeer
Cytomegalovirus infection of the developing brain alters catecholamine and indoleamine metabolism.
Brain research 1991;559(2):322-30.
1991: Patrick L McGeer; Edith G McGeer; T Kawamata; Tatsuo Yamada; Haruhiko Akiyama
Reactions of the immune system in chronic degenerative neurological diseases.
The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 1991;18(3 Suppl):376-9.
1991: Patrick L McGeer; Douglas G. Walker; Haruhiko Akiyama; T Kawamata; A L Guan; C J Parker; N Okada; Edith G McGeer
Detection of the membrane inhibitor of reactive lysis (CD59) in diseased neurons of Alzheimer brain.
Brain research 1991;544(2):315-9.
1990: Edith G McGeer; Patrick L McGeer; R Harrop; Haruhiko Akiyama; H Kamo
Correlations of regional postmortem enzyme activities with premortem local glucose metabolic rates in Alzheimer's disease.
Journal of neuroscience research 1990;27(4):612-9.
1990: Tatsuo Yamada; Patrick L McGeer; Kenneth G Baimbridge; Edith G McGeer
Relative sparing in Parkinson's disease of substantia nigra dopamine neurons containing calbindin-D28K.
Brain research 1990;526(2):303-7.
1990: Edith G McGeer; S G Zhu
Lamotrigine protects against kainate but not ibotenate lesions in rat striatum.
Neuroscience letters 1990;112(2-3):348-51.
1990: M Mildenberger; Thomas Beach; Edith G McGeer; C M Ludgate
An animal model of prophylactic cranial irradiation: histologic effects at acute, early and delayed stages.
International journal of radiation oncology, biology, physics 1990;18(5):1051-60.
1990: Patrick L McGeer; Edith G McGeer; Joseph Rogers; J Sibley
Anti-inflammatory drugs and Alzheimer disease.
Lancet 1990;335(8696):1037.
1990: Edith G McGeer; R P Peppard; Patrick L McGeer; Holly A Tuokko; D Crockett; R Parks; Haruhiko Akiyama; Donald B Calne; B L Beattie; R Harrop
18Fluorodeoxyglucose positron emission tomography studies in presumed Alzheimer cases, including 13 serial scans.
The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 1990;17(1):1-11.
1990: S G Zhu; Edith G McGeer; Patrick L McGeer
gamma-Glutamyltransferase activity is unchanged in acutely quinolinate-lesioned rat neostriatum but is elevated in Huntington's disease caudate.
Experimental neurology 1990;107(1):106-9.
1989: Patrick L McGeer; Haruhiko Akiyama; S Itagaki; Edith G McGeer
Activation of the classical complement pathway in brain tissue of Alzheimer patients.
Neuroscience letters 1989;107(1-3):341-6.
1989: Barry Boyes; Douglas G. Walker; Edith G McGeer; John R O'Kusky
Increased uric acid in the developing brain and spinal cord following cytomegalovirus infection.
Journal of neurochemistry 1989;53(6):1719-23.
1989: S Itagaki; Patrick L McGeer; Haruhiko Akiyama; B L Beattie; Douglas G. Walker; G R Moore; Edith G McGeer
A case of adult-onset dementia with argyrophilic grains.
Annals of neurology 1989;26(5):685-9.
1989: Patrick L McGeer; Haruhiko Akiyama; S Itagaki; Edith G McGeer
Immune system response in Alzheimer's disease.
The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 1989;16(4 Suppl):516-27.
1989: Edith G McGeer; Patrick L McGeer; Haruhiko Akiyama; R Harrop
Cortical glutaminase, beta-glucuronidase and glucose utilization in Alzheimer's disease.
The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 1989;16(4 Suppl):511-5.
1989: Douglas G. Walker; Barry Boyes; Patrick L McGeer; Edith G McGeer
Strategies for the identification of novel brain specific genes affected in Alzheimer disease.
The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 1989;16(4 Suppl):483-9.
1989: Thomas Beach; R Walker; Edith G McGeer
Lamina-selective A68 immunoreactivity in primary visual cortex of Alzheimer's disease patients.
Brain research 1989;501(1):171-4.
1989: John R O'Kusky; Edith G McGeer
Methylmercury-induced movement and postural disorders in developing rat: high-affinity uptake of choline, glutamate, and gamma-aminobutyric acid in the cerebral cortex and caudate-putamen.
Journal of neurochemistry 1989;53(4):999-1006.
1989: Edith G McGeer
Excitatory amino acids and Alzheimer's disease: idle thoughts on an exciting subject.
Neurobiology of aging 1989;10(5):614-6; discussion 618-20.
1989: H Tago; Patrick L McGeer; Edith G McGeer; Haruhiko Akiyama; Louis B Hersh
Distribution of choline acetyltransferase immunopositive structures in the rat brainstem.
Brain research 1989;495(2):271-97.
1989: Edith G McGeer; Patrick L McGeer
Effect of fixatives on rat brain acetylcholinesterase activity.
Journal of neuroscience methods 1989;28(3):235-7.
1989: Haruhiko Akiyama; R Harrop; Patrick L McGeer; R Peppard; Edith G McGeer
Crossed cerebellar and uncrossed basal ganglia and thalamic diaschisis in Alzheimer's disease.
Neurology 1989;39(4):541-8.
1989: Haruhiko Akiyama; Patrick L McGeer; S Itagaki; Edith G McGeer; T Kaneko
Loss of glutaminase-positive cortical neurons in Alzheimer's disease.
Neurochemical research 1989;14(4):353-8.
1989: S G Zhu; Edith G McGeer; Patrick L McGeer
Effect of MK-801, kynurenate, glycine, dextrorphan and 4-acetylpyridine on striatal toxicity of quinolinate.
Brain research 1989;481(2):356-60.
1989: K Semba; Peter B Reiner; Edith G McGeer; HC Fibiger
Brainstem projecting neurons in the rat basal forebrain: neurochemical, topographical, and physiological distinctions from cortically projecting cholinergic neurons.
Brain research bulletin 1989;22(3):501-9.
1989: K Mizukawa; S R Vincent; Patrick L McGeer; Edith G McGeer
Distribution of reduced-nicotinamide-adenine-dinucleotide-phosphate diaphorase-positive cells and fibers in the cat central nervous system.
The Journal of comparative neurology 1989;279(2):281-311.
1989: Thomas Beach; R Walker; Edith G McGeer
Patterns of gliosis in Alzheimer's disease and aging cerebrum.
Glia 1989;2(6):420-36.
1989: R W Parks; D J Crockett; Holly A Tuokko; B L Beattie; J W Ashford; Kerry L Coburn; R F Zec; R E Becker; Patrick L McGeer; Edith G McGeer
Neuropsychological "systems efficiency" and positron emission tomography.
The Journal of neuropsychiatry and clinical neurosciences 1989;1(3):269-82.
1988: S G Zhu; Edith G McGeer; E A Singh; Patrick L McGeer
Tetrahydroaminoacridine potentiates neurotoxicity of quinolinic acid in rat striatum.
Neuroscience letters 1988;95(1-3):252-6.
1988: K Mizukawa; N Otsuka; Patrick L McGeer; S R Vincent; Edith G McGeer
The ultrastructure of somatostatin-immunoreactive cell bodies, nerve fibers and terminals in the dorsal horn of rat spinal cord.
Archives of histology and cytology 1988;51(5):443-52.
1988: Thomas Beach; Edith G McGeer
Lamina-specific arrangement of astrocytic gliosis and senile plaques in Alzheimer's disease visual cortex.
Brain research 1988;463(2):357-61.
1988: Edith G McGeer; Patrick L McGeer
The dystonias.
The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 1988;15(4):447-83.
1988: Peter B Reiner; Edith G McGeer
THA increases action potential duration of central histamine neurons in vitro.
European journal of pharmacology 1988;155(3):265-70.
1988: Peter B Reiner; K Semba; HC Fibiger; Edith G McGeer
Ontogeny of histidine-decarboxylase-immunoreactive neurons in the tuberomammillary nucleus of the rat hypothalamus: time of origin and development of transmitter phenotype.
The Journal of comparative neurology 1988;276(2):304-11.
1988: K Mizukawa; S R Vincent; Patrick L McGeer; Edith G McGeer
Reduced nicotinamide adenine dinucleotide phosphate (NADPH)-diaphorase-positive neurons in cat cerebral white matter.
Brain research 1988;461(2):274-81.
1988: Patrick L McGeer; S Itagaki; Haruhiko Akiyama; Edith G McGeer
Rate of cell death in parkinsonism indicates active neuropathological process.
Annals of neurology 1988;24(4):574-6.
1988: Patrick L McGeer; S Itagaki; Barry Boyes; Edith G McGeer
Reactive microglia are positive for HLA-DR in the substantia nigra of Parkinson's and Alzheimer's disease brains.
Neurology 1988;38(8):1285-91.
1988: K Mizukawa; Patrick L McGeer; S R Vincent; Edith G McGeer
Ultrastructure of reduced nicotinamide adenine dinucleotide phosphate (NADPH) diaphorase-positive neurons in the cat cerebral cortex, amygdala and caudate nucleus.
Brain research 1988;452(1-2):286-92.
1988: Thomas Beach; Edith G McGeer
Retrograde filling of pyramidal neurons in postmortem human cerebral cortex using horseradish peroxidase.
Journal of neuroscience methods 1988;23(3):187-93.
1988: John R O'Kusky; Barry Boyes; Edith G McGeer
Methylmercury-induced movement and postural disorders in developing rat: regional analysis of brain catecholamines and indoleamines.
Brain research 1988;439(1-2):138-46.
1988: P Cumming; M Häusser; W R Wayne Martin; J Grierson; M J Adam; Thomas J Ruth; Edith G McGeer
Kinetics of in vitro decarboxylation and the in vivo metabolism of 2-18F- and 6-18F-fluorodopa in the hooded rat.
Biochemical pharmacology 1988;37(2):247-50.
1988: K Semba; Peter B Reiner; Edith G McGeer; HC Fibiger
Brainstem afferents to the magnocellular basal forebrain studied by axonal transport, immunohistochemistry, and electrophysiology in the rat.
The Journal of comparative neurology 1988;267(3):433-53.
1988: K Semba; Peter B Reiner; Edith G McGeer; HC Fibiger
Non-cholinergic basal forebrain neurons project to the contralateral basal forebrain in the rat.
Neuroscience letters 1988;84(1):23-8.
1988: Patrick L McGeer; S Itagaki; H Tago; Edith G McGeer
Occurrence of HLA-DR reactive microglia in Alzheimer's disease.
Annals of the New York Academy of Sciences 1988;540():319-23.
1988: Patrick L McGeer; S Itagaki; Edith G McGeer
Expression of the histocompatibility glycoprotein HLA-DR in neurological disease.
Acta neuropathologica 1988;76(6):550-7.
1988: Edith G McGeer; E A Singh; Patrick L McGeer
Peripheral-type benzodiazepine binding in Alzheimer disease.
Alzheimer disease and associated disorders 1988;2(4):331-6.
1987: P Cumming; H Kamo; Edith G McGeer; Patrick L McGeer
Toxicity of p-methoxyphenol to dopamine neurons in the rat substantia nigra.
Neuropharmacology 1987;26(12):1795-7.
1987: K Mizukawa; Patrick L McGeer; Steven R Vincent; Edith G McGeer
The distribution of somatostatin-immunoreactive neurons and fibers in the rat cerebral cortex: light and electron microscopic studies.
Brain research 1987;426(1):28-36.
1987: Thomas Beach; Edith G McGeer
Further methodological problems in cell counting.
Neurobiology of aging 1987;8(6):570-1.
1987: Patrick L McGeer; S Itagaki; H Tago; Edith G McGeer
Reactive microglia in patients with senile dementia of the Alzheimer type are positive for the histocompatibility glycoprotein HLA-DR.
Neuroscience letters 1987;79(1-2):195-200.
1987: H Tago; P B Reiner; Edith G McGeer
Coupled intracellular horseradish peroxidase-monoamine oxidase histochemistry: description of the technique and its application to the study of physiologically identified tuberomammillary neurons.
Journal of neuroscience methods 1987;20(4):271-81.
1987: P Cumming; Barry Boyes; W R Wayne Martin; M Adam; Thomas J Ruth; Edith G McGeer
Altered metabolism of [18F]-6-fluorodopa in the hooded rat following inhibition of catechol-O-methyltransferase with U-0521.
Biochemical pharmacology 1987;36(15):2527-31.
1987: Patrick L McGeer; Edith G McGeer; S Itagaki; K Mizukawa
Anatomy and pathology of the basal ganglia.
The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 1987;14(3 Suppl):363-72.
1987: Edith G McGeer; E A Singh; Patrick L McGeer
Sodium-dependent glutamate binding in senile dementia.
Neurobiology of aging 1987;8(3):219-23.
1987: Thomas Beach; Edith G McGeer
Tract-tracing with horseradish peroxidase in the postmortem human brain.
Neuroscience letters 1987;76(1):37-41.
1987: Thomas Beach; H Tago; Edith G McGeer
Light microscopic evidence for a substance P-containing innervation of the human nucleus basalis of Meynert.
Brain research 1987;408(1-2):251-7.
1987: H Tago; Patrick L McGeer; Edith G McGeer
Acetylcholinesterase fibers and the development of senile plaques.
Brain research 1987;406(1-2):363-9.
1987: H Kamo; Patrick L McGeer; R Harrop; Edith G McGeer; Donald B Calne; W R Wayne Martin; B D Pate
Positron emission tomography and histopathology in Pick's disease.
Neurology 1987;37(3):439-45.
1987: Thomas Beach; H Tago; T Nagai; H Kimura; Patrick L McGeer; Edith G McGeer
Perfusion-fixation of the human brain for immunohistochemistry: comparison with immersion-fixation.
Journal of neuroscience methods 1987;19(3):183-92.
1987: K Semba; P B Reiner; Edith G McGeer; H C Fibiger
Morphology of cortically projecting basal forebrain neurons in the rat as revealed by intracellular iontophoresis of horseradish peroxidase.
Neuroscience 1987;20(2):637-51.
1987: P B Reiner; K Semba; H C Fibiger; Edith G McGeer
Physiological evidence for subpopulations of cortically projecting basal forebrain neurons in the anesthetized rat.
Neuroscience 1987;20(2):629-36.
1987: P Cumming; Barry Boyes; W R Wayne Martin; M Adam; J Grierson; Thomas J Ruth; Edith G McGeer
The metabolism of [18F]6-fluoro-L-3,4-dihydroxyphenylalanine in the hooded rat.
Journal of neurochemistry 1987;48(2):601-8.
1987: P B Reiner; Edith G McGeer
Electrophysiological properties of cortically projecting histamine neurons of the rat hypothalamus.
Neuroscience letters 1987;73(1):43-7.
1987: Edith G McGeer; E A Singh; Patrick L McGeer
gamma-Glutamyltransferase: normal cortical levels in Alzheimer disease.
Alzheimer disease and associated disorders 1987;1(1):38-42.
1986: Barry Boyes; P Cumming; W R Wayne Martin; Edith G McGeer
Determination of plasma [18F]-6-fluorodopa during positron emission tomography: elimination and metabolism in carbidopa treated subjects.
Life sciences 1986;39(23):2243-52.
1986: Patrick L McGeer; H Kamo; R Harrop; Edith G McGeer; W R Wayne Martin; B D Pate; D K Li
Comparison of PET, MRI, and CT with pathology in a proven case of Alzheimer's disease.
Neurology 1986;36(12):1569-74.
1986: Donald B Calne; A Eisen; Edith G McGeer; Peter S Spencer
Alzheimer's disease, Parkinson's disease, and motoneurone disease: abiotrophic interaction between ageing and environment?
Lancet 1986;2(8515):1067-70.
1986: Edith G McGeer; Patrick L McGeer; H Kamo; H Tago; R Harrop
Cortical metabolism, acetylcholinesterase staining and pathological changes in Alzheimer's disease.
The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 1986;13(4 Suppl):511-6.
1986: K Mizukawa; Patrick L McGeer; H Tago; J H Peng; Edith G McGeer; H Kimura
The cholinergic system of the human hindbrain studied by choline acetyltransferase immunohistochemistry and acetylcholinesterase histochemistry.
Brain research 1986;379(1):39-55.
1986: J H Peng; Patrick L McGeer; Edith G McGeer
Membrane-bound choline acetyltransferase from human brain: purification and properties.
Neurochemical research 1986;11(7):959-71.
1986: Patrick L McGeer; H Kamo; R Harrop; D K Li; Holly A Tuokko; Edith G McGeer; M J Adam; W Ammann; B L Beattie; Donald B Calne
Positron emission tomography in patients with clinically diagnosed Alzheimer's disease.
CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 1986;134(6):597-607.
1986: Edith G McGeer; Patrick L McGeer
Possible destruction of cholinoceptive neurons by overstimulation of cholinergic tracts.
Canadian journal of physiology and pharmacology 1986;64(3):363-8.
1986: P Cumming; M Von Krosigk; Peter B Reiner; Edith G McGeer; S R Vincent
Absence of adrenaline neurons in the guinea pig brain: a combined immunohistochemical and high-performance liquid chromatography study.
Neuroscience letters 1986;63(2):125-30.
1986: Patrick L McGeer; Edith G McGeer; H Kamo; K Wong
Positron emission tomography and the possible origins of cytopathology in Alzheimer's disease.
Progress in neuro-psychopharmacology & biological psychiatry 1986;10(3-5):501-18.
1985: S G Thompson; Edith G McGeer
GABA-transaminase and glutamic acid decarboxylase changes in the brain of rats treated with pyrithiamine.
Neurochemical research 1985;10(12):1653-60.
1985: S G Thompson; P T Wong; S F Leong; Edith G McGeer
Regional distribution in rat brain of 1-pyrroline-5-carboxylate dehydrogenase and its localization to specific glial cells.
Journal of neurochemistry 1985;45(6):1791-6.
1985: J R O'Kusky; Edith G McGeer
Methylmercury poisoning of the developing nervous system in the rat: decreased activity of glutamic acid decarboxylase in cerebral cortex and neostriatum.
Brain research 1985;353(2):299-306.
1985: M Araki; Patrick L McGeer; Edith G McGeer
Striatonigral and pallidonigral pathways studied by a combination of retrograde horseradish peroxidase tracing and a pharmacohistochemical method for gamma-aminobutyric acid transaminase.
Brain research 1985;331(1):17-24.
1985: Edith G McGeer; M Norman; Barry Boyes; J O'Kusky; J Suzuki; Patrick L McGeer
Acetylcholine and aromatic amine systems in postmortem brain of an infant with Down's syndrome.
Experimental neurology 1985;87(3):557-70.
1985: M Araki; Patrick L McGeer; Edith G McGeer
Differential effect of kainic acid on somatostatin, GABAergic and cholinergic neurons in the rat striatum.
Neuroscience letters 1985;53(2):197-202.
1985: T Nagai; T Maeda; H Imai; Patrick L McGeer; Edith G McGeer
Distribution of GABA-T-intensive neurons in the rat hindbrain.
The Journal of comparative neurology 1985;231(2):260-9.
1984: Edith G McGeer; E Singh
Neurotoxic effects of endogenous materials: quinolinic acid, L-pyroglutamic acid, and thyroid releasing hormone (TRH).
Experimental neurology 1984;86(2):410-3.
1984: M Araki; Patrick L McGeer; Edith G McGeer
Presumptive gamma-aminobutyric acid pathways from the midbrain to the superior colliculus studied by a combined horseradish peroxidase-gamma-aminobutyric acid transaminase pharmacohistochemical method.
Neuroscience 1984;13(2):433-9.
1984: Thomas Beach; Edith G McGeer
The distribution of substance P in the primate basal ganglia: an immunohistochemical study of baboon and human brain.
Neuroscience 1984;13(1):29-52.
1984: M Araki; Patrick L McGeer; Edith G McGeer
Retrograde HRP tracing combined with a pharmacohistochemical method for GABA transaminase for the identification of presumptive GABAergic projections to the habenula.
Brain research 1984;304(2):271-7.
1984: Patrick L McGeer; Edith G McGeer; J H Peng
Choline acetyltransferase: purification and immunohistochemical localization.
Life sciences 1984;34(24):2319-38.
1984: Patrick L McGeer; Edith G McGeer; J Suzuki; C E Dolman; T Nagai
Aging, Alzheimer's disease, and the cholinergic system of the basal forebrain.
Neurology 1984;34(6):741-5.
1984: Edith G McGeer; Patrick L McGeer
Substantia nigra cell death from kainic acid or folic acid injections into the pontine tegmentum.
Brain research 1984;298(2):339-42.
1984: Edith G McGeer; W A Staines; Patrick L McGeer
Neurotransmitters in the basal ganglia.
The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 1984;11(1 Suppl):89-99.
1984: P T Wong; V K Singh; Edith G McGeer
Sodium-independent glutamic acid binding in cultured fibroblasts from patients with Huntington's disease.
Neurochemistry international 1984;6(2):245-7.
1984: Donald B Calne; RC Duvoisin; Edith G McGeer
Speculations on the etiology of Parkinson's disease.
Advances in neurology 1984;40():353-60.
1983: Thomas Beach; Edith G McGeer
Neocortical substance P neurons in the baboon: an immunohistochemical finding.
Neuroscience letters 1983;41(3):265-70.
1983: J H Peng; Patrick L McGeer; Edith G McGeer
Anti-human choline acetyltransferase fragments antigen binding (FAB)-sepharose chromatography for enzyme purification.
Neurochemical research 1983;8(11):1481-6.
1983: U Scherer-Singler; S R Vincent; H Kimura; Edith G McGeer
Demonstration of a unique population of neurons with NADPH-diaphorase histochemistry.
Journal of neuroscience methods 1983;9(3):229-34.
1983: T Nagai; Patrick L McGeer; Edith G McGeer
Distribution of GABA-T-intensive neurons in the rat forebrain and midbrain.
The Journal of comparative neurology 1983;218(2):220-38.
1983: Patrick L McGeer; Edith G McGeer
Excitotoxic amino acids as tools in neurobiology.
Reviews in pure & applied pharmacological sciences 1983;4(3):213-70.
1983: P T Wong; Edith G McGeer; K Singh; Patrick L McGeer
Changes in muscarinic binding in distant brain regions showing neuronal losses after folic acid injections into the substantia innominata.
Journal of neurochemistry 1983;40(6):1754-7.
1983: Y Noda; Patrick L McGeer; Edith G McGeer
Lipid peroxide distribution in brain and the effect of hyperbaric oxygen.
Journal of neurochemistry 1983;40(5):1329-32.
1983: T Nagai; T Pearson; F Peng; Edith G McGeer; Patrick L McGeer
Immunohistochemical staining of the human forebrain with monoclonal antibody to human choline acetyltransferase.
Brain research 1983;265(2):300-6.
1983: T Nagai; Patrick L McGeer; J H Peng; Edith G McGeer; C E Dolman
Choline acetyltransferase immunohistochemistry in brains of Alzheimer's disease patients and controls.
Neuroscience letters 1983;36(2):195-9.
1983: Patrick L McGeer; Edith G McGeer; T Nagai
GABAergic and cholinergic indices in various regions of rat brain after intracerebral injections of folic acid.
Brain research 1983;260(1):107-16.
1983: Patrick L McGeer; Edith G McGeer; T Nagai; P T Wong
A possible relationship between folic acid neurotoxicity and cholinergic receptors in the pyriform cortex and amygdala.
Journal of neural transmission. Supplementum 1983;18():327-44.
1982: S R Vincent; H Kimura; Edith G McGeer
GABA-transaminase in the basal ganglia: a pharmacohistochemical study.
Brain research 1982;251(1):93-104.
1982: J H Peng; Patrick L McGeer; Edith G McGeer
Cross-reactivity of antibodies to chicken brain choline acetyltransferase with mammalian enzyme.
Journal of neuroimmunology 1982;3(2):113-21.
1982: Y Noda; J A Wada; Edith G McGeer
Lasting influence of amygdaloid kindling on cholinergic neurotransmission.
Experimental neurology 1982;78(1):91-8.
1982: S R Vincent; H Kimura; Edith G McGeer
A histochemical study of GABA-transaminase in the efferents of the pallidum.
Brain research 1982;241(1):162-5.
1982: T Nagai; H Kimura; T Maeda; Patrick L McGeer; F Peng; Edith G McGeer
Cholinergic projections from the basal forebrain of rat to the amygdala.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1982;2(4):513-20.
1982: Patrick L McGeer; Edith G McGeer
Kainic acid: The neurotoxic breakthrough.
Critical reviews in toxicology 1982;10(1):1-26.
1982: P T Wong; Patrick L McGeer; Martin N Rossor; Edith G McGeer
Ornithine aminotransferase in Huntington's disease.
Brain research 1982;231(2):466-71.
1982: Y Noda; Patrick L McGeer; Edith G McGeer
Lipid peroxides in brain during aging and vitamin E deficiency: possible relations to changes in neurotransmitter indices.
Neurobiology of aging 1982;3(3):173-8.
1982: P T Wong; Edith G McGeer; Patrick L McGeer
Effects of kainic acid injection and cortical lesion on ornithine and aspartate aminotransferases in rat striatum.
Journal of neuroscience research 1982;8(4):643-50.
1981: S R Vincent; H Kimura; Edith G McGeer
The histochemical localization of GABA-transaminase in the efferents of the striatum.
Brain research 1981;222(1):198-203.
1981: H Kimura; Patrick L McGeer; J H Peng; Edith G McGeer
The central cholinergic system studied by choline acetyltransferase immunohistochemistry in the cat.
The Journal of comparative neurology 1981;200(2):151-201.
1981: P T Wong; Edith G McGeer
Postnatal changes of GABAergic and glutamatergic parameters.
Brain research 1981;227(4):519-29.
1981: S R Vincent; Edith G McGeer
A substance P projection to the hippocampus.
Brain research 1981;215(1-2):349-51.
1981: S R Vincent; H Kimura; Edith G McGeer
Organization of substance P fibers within the hippocampal formation demonstrated with a biotin-avidin immunoperoxidase technique.
The Journal of comparative neurology 1981;199(1):113-23.
1981: J H Peng; H Kimura; Patrick L McGeer; Edith G McGeer
Anti-choline acetyltransferase fragments antigen binding (Fab) for immunohistochemistry.
Neuroscience letters 1981;21(3):281-5.
1981: P T Wong; Edith G McGeer; Patrick L McGeer
A sensitive radiometric assay for ornithine aminotransferase: regional and subcellular distributions in rat brain.
Journal of neurochemistry 1981;36(2):501-5.
1981: J A McCaughran; Edith G McGeer
Iontophoresis of kainic acid.
Neurochemical research 1981;6(1):97-8.
1981: Edith G McGeer
Neurotransmitter systems in aging and senile dementia.
Progress in neuro-psychopharmacology 1981;5(5-6):435-45.
1981: Edith G McGeer; Patrick L McGeer
Neurotoxins as tools in neurobiology.
International review of neurobiology 1981;22():173-204.
1980: W A Staines; H Kimura; H C Fibiger; Edith G McGeer
Peroxidase-labeled lectin as a neuroanatomical tracer: evaluation in a CNS pathway.
Brain research 1980;197(2):485-90.
1980: J H Peng; Patrick L McGeer; H Kimura; S C Sung; Edith G McGeer
Purification and immunochemical properties of choline acetyltransferase from human brain.
Neurochemical research 1980;5(9):943-62.
1980: S R Vincent; J Lehmann; Edith G McGeer
The localization of GABA-transaminase in the striato-nigral system.
Life sciences 1980;27(7):595-601.
1980: S R Vincent; W A Staines; Edith G McGeer; H C Fibiger
Transmitters contained in the efferents of the habenula.
Brain research 1980;195(2):479-84.
1980: Edith G McGeer; A Jakubovic; E A Singh
Ethanol, baclofen, and kainic acid neurotoxicity.
Experimental neurology 1980;69(2):359-64.
1980: H Kimura; Patrick L McGeer; F Peng; Edith G McGeer
Choline acetyltransferase-containing neurons in rodent brain demonstrated by immunohistochemistry.
Science (New York, N.Y.) 1980;208(4447):1057-9.
1980: Edith G McGeer; E A Singh
Possible cortico-hypothalamic glycinergic tract.
Neuroscience letters 1980;17(1-2):85-7.
1980: S R Vincent; H Kimura; Edith G McGeer
The pharmacohistochemical demonstration of GABA-transaminase.
Neuroscience letters 1980;16(3):345-8.
1980: S R Vincent; Edith G McGeer
A comparison of sodium-dependent glutamate binding with high-affinity glutamate uptake in rat striatum.
Brain research 1980;184(1):99-108.
1980: A P Zis; P J Marangos; A M Parma; Edith G McGeer
Changes in striatal neuron-specific enolase (NSE) and non-neuronal enolase (NNE) following kainic acid administration.
Brain research 1980;183(2):486-9.
1980: Patrick L McGeer; Edith G McGeer; J J Campbell
Rotatory effects of intracerebral tetanus toxin injections.
Experimental neurology 1980;67(2):363-7.
1980: W A Staines; A M Benjamin; Edith G McGeer
Cysteinesulfinate decarboxylase activity as an index of taurine-containing structures.
Journal of neuroscience research 1980;5(6):555-62.
1980: H Kimura; Edith G McGeer; Patrick L McGeer
Metabolic alterations in an animal model of Huntington's disease using the 14C-deoxyglucose method.
Journal of neural transmission. Supplementum 1980;(16):103-9.
1980: Patrick L McGeer; Edith G McGeer; V T Innanen
Kainic acid and neurotransmitter interactions in the basal ganglia.
Advances in biochemical psychopharmacology 1980;24():185-91.
1980: Edith G McGeer; Patrick L McGeer
Aging and neurotransmitter systems.
Advances in biochemical psychopharmacology 1980;23():305-14.
1980: Patrick L McGeer; Edith G McGeer
Chemistry of mood and emotion.
Annual review of psychology 1980;31():273-307.
1979: A Purdy; A Hahn; H J Barnett; P Bratty; D Ahmad; K G Lloyd; Edith G McGeer; T L Perry
Familial fatal Parkinsonism with alveolar hypoventilation and mental depression.
Annals of neurology 1979;6(6):523-31.
1979: A Jakubovic; Edith G McGeer
Narcotics and rat testicular metabolism.
Molecular pharmacology 1979;16(3):970-80.
1979: V K Singh; Edith G McGeer
Binding of [3H]histamine to receptor sites in rat brain.
Experimental neurology 1979;66(2):413-8.
1979: S R Vincent; Edith G McGeer
Structural specificity of high affinity [3H]-glutamate uptake in striatal homogenates.
The Journal of pharmacy and pharmacology 1979;31(10):703-4.
1979: Edith G McGeer; Patrick L McGeer; S R Vincent
Morphine, naloxone and kainic acid neurotoxicity.
Research communications in chemical pathology and pharmacology 1979;25(2):411-4.
1979: T Hattori; Patrick L McGeer; Edith G McGeer
Dendro axonic neurotransmission. II. Morphological sites for the synthesis, binding and release of neurotransmitters in dopaminergic dendrites in the substantia nigra and cholinergic dendrites in the neostriatum.
Brain research 1979;170(1):71-83.
1979: W J Boyko; C K Galabru; Edith G McGeer; Patrick L McGeer
Thalamic injections of kainic acid produce myocardial necrosis.
Life sciences 1979;25(1):87-98.
1979: A Jakubovic; Edith G McGeer; Patrick L McGeer
Effects of cannabinoids on testosterone and protein synthesis in rat testis Leydig cells in vitro.
Molecular and cellular endocrinology 1979;15(1):41-50.
1979: Patrick L McGeer; Edith G McGeer; V T Innanen
Dendro axonic transmission. I. Evidence from receptor binding of dopaminergic and cholinergic agents.
Brain research 1979;169(3):433-41.
1979: Edith G McGeer; U Scherer-Singler; E A Singh
Confirmatory data on habenular projections.
Brain research 1979;168(2):375-6.
1979: T Hattori; Edith G McGeer; Patrick L McGeer
Fine structural analysis of the cortico-striatal pathway.
The Journal of comparative neurology 1979;185(2):347-53.
1979: Paul Sanberg; M Pisa; Edith G McGeer
Strain differences and kainic acid neurotoxicity.
Brain research 1979;166(2):431-5.
1979: A Jakubovic; D Lin; Edith G McGeer
Protein and RNA synthesis in kainic acid-injected striata.
Brain research 1979;163(2):289-94.
1979: U Scherer-Singler; Edith G McGeer
Distribution and persistence of kainic acid in brain.
Life sciences 1979;24(11):1015-22.
1979: Edith G McGeer; Patrick L McGeer
Localization of glutaminase in the rat neostriatum.
Journal of neurochemistry 1979;32(3):1071-5.
1979: Paul Sanberg; W Staines; Edith G McGeer
Chronic taurine effects on various neurochemical indices in control and kainic acid-lesioned neostriatum.
Brain research 1979;161(2):367-70.
1979: S R Vincent; Edith G McGeer
Kainic acid binding to membranes of striatal neurons.
Life sciences 1979;24(3):265-70.
1979: Edith G McGeer; Patrick L McGeer; T Hattori; V K Singh
Immunohistochemistry of choline acetyltransferase.
Progress in brain research 1979;49():59-70.
1979: E A Singh; Edith G McGeer
Postnatal activity of angiotensin converting enzyme in rat brain.
Developmental neuroscience 1979;2(5):245-8.
1979: Patrick L McGeer; Edith G McGeer
Use of the neurotoxic agents kainic acid and tetanus toxin in the extrapyramidal system.
Advances in cytopharmacology 1979;3():437-46.
1979: Patrick L McGeer; Edith G McGeer; T Hattori
Biochemical interactions in the basal ganglia.
Progress in brain research 1979;51():285-301.
1978: A Jakubovic; Edith G McGeer; Patrick L McGeer
Effects of d1-methadone and morphine on developing chick embryo.
Experientia 1978;34(12):1617-8.
1978: S C Sung; P R Sandberg; Edith G McGeer
Cholinergic systems in muscle and brain in vitamin E-deficient rats.
Neurochemical research 1978;3(6):815-20.
1978: Edith G McGeer; Patrick L McGeer
Some factors influencing the neurotoxicity of intrastriatal injections of kainic acid.
Neurochemical research 1978;3(4):501-17.
1978: S R Vincent; T Hattori; Edith G McGeer
The nigrotectal projection: a biochemical and ultrastructural characterization.
Brain research 1978;151(1):159-64.
1978: A Jakubovic; Edith G McGeer; Patrick L McGeer
Biochemical alterations induced by cannabinoids in the Leydig cells of the rat testis in vitro: effects on testosterone and protein synthesis.
Advances in the biosciences 1978;22-23():251-64.
1978: E A Singh; Edith G McGeer
Angiotensin converting enzyme in kainic acid--injected striata.
Annals of neurology 1978;4(1):85-6.
1978: J I Nagy; S R Vincent; J Lehmann; H C Fibiger; Edith G McGeer
The use of kainic acid in the localization of enzymes in the substantia nigra.
Brain research 1978;149(2):431-41.
1978: V K Singh; Edith G McGeer; Patrick L McGeer
Changes of [3H]colchicine binding and protein synthesis in the rat striatum following kainic acid lesions.
Brain research 1978;146(1):195-9.
1978: Edith G McGeer; V K Singh; J Parkinson; U Scherer
Effects of morphine on axonal transport in nigrostriatal neurons.
Experimental neurology 1978;59(2):342-50.
1978: Edith G McGeer; Patrick L McGeer; K Singh
Kainate-induced degeneration of neostriatal neurons: dependency upon corticostriatal tract.
Brain research 1978;139(2):381-3.
1978: A Jakubovic; Edith G McGeer; Patrick L McGeer
Comparative inhibition of biosynthetic processes in rat liver testicular cells by D-, L,-and DL-methadone.
Biochemical pharmacology 1978;27(1):123-5.
1978: Patrick L McGeer; Edith G McGeer
Aging and neurotransmitter systems.
Advances in experimental medicine and biology 1978;113():41-57.
1978: Patrick L McGeer; Edith G McGeer
Intracerebral injections of kainic acid and tetanus toxin: possible models for the signs of chorea and dystonia.
Advances in neurology 1978;21():331-8.
1977: Edith G McGeer; U Scherer; E A Singh
Axonal transport in the habenulo--interpeduncular tract.
Experimental neurology 1977;57(3):682-6.
1977: Patrick L McGeer; Edith G McGeer
Possible changes in striatal and limbic cholinergic systems in schizophrenia.
Archives of general psychiatry 1977;34(11):1319-23.
1977: T Hattori; Edith G McGeer
Fine structural changes in the rat striatum after local injections of kainic acid.
Brain research 1977;129(1):174-80.
1977: Patrick L McGeer; Edith G McGeer; U Scherer; K Singh
A glutamatergic corticostriatal path?
Brain research 1977;128(2):369-73.
1977: T Hattori; Edith G McGeer; V K Singh; Patrick L McGeer
Cholinergic synapse of the interpeduncular nucleus.
Experimental neurology 1977;55(3 PT. 1):666-79.
1977: V K Singh; Edith G McGeer
Choline acetyltransferase in developing rat brain and spinal cord.
Brain research 1977;127(1):159-63.
1977: Patrick L McGeer; Edith G McGeer; T Hattori
Dopamine-acetylcholine-GABA neuronal linkages in the extrapyramidal and limbic systems.
Advances in biochemical psychopharmacology 1977;16():397-402.
1977: Patrick L McGeer; Edith G McGeer; J S Suzuki
Aging and extrapyramidal function.
Archives of neurology 1977;34(1):33-5.
1976: Edith G McGeer; V T Innanen; Patrick L McGeer
Evidence on the cellular localization of adenyl cyclase in the neostriatum.
Brain research 1976;118(2):356-8.
1976: Edith G McGeer; Patrick L McGeer
Duplication of biochemical changes of Huntington's chorea by intrastriatal injections of glutamic and kainic acids.
Nature 1976;263(5577):517-9.
1976: Edith G McGeer; J Parkinson; Patrick L McGeer
Neonatal enzymic development in the interpeduncular nucleus and surrounding ventral tegmentum.
Experimental neurology 1976;53(1):109-14.
1976: T Hattori; V K Singh; Edith G McGeer; Patrick L McGeer
Immunohistochemical localization of choline acetyltransferase containing neostriatal neurons and their relationship with dopaminergic synapses.
Brain research 1976;102(1):164-73.
1976: Patrick L McGeer; T Hattori; V K Singh; Edith G McGeer
Cholinergic systems in extrapyramidal function.
Research publications - Association for Research in Nervous and Mental Disease 1976;55():213-26.
1976: Patrick L McGeer; Edith G McGeer
Enzymes associated with the metabolism of catecholamines, acetylcholine and gaba in human controls and patients with Parkinson's disease and Huntington's chorea.
Journal of neurochemistry 1976;26(1):65-76.
1975: Edith G McGeer; L Maler
GABA accumulation by embryonic chick tectum.
Developmental biology 1975;47(2):464-5.
1975: V K Singh; Edith G McGeer; Patrick L McGeer
Two immunologically different choline acetyltransferases in human neostriatum.
Brain research 1975;96(1):187-91.
1975: Patrick L McGeer; Edith G McGeer
Evidence for glutamic acid decarboxylase-containing interneurons in the neostriatum.
Brain research 1975;91(2):331-5.
1975: Patrick L McGeer; T Hattori; Edith G McGeer
Chemical and autoradiographic analysis of gamma-aminobutyric acid transport in Purkinje cells of the cerebellum.
Experimental neurology 1975;47(1):26-41.
1975: Edith G McGeer; T Hattori; Patrick L McGeer
Electron microscopic localization of labeled norepinephrine transported in nigro-striatal neurons.
Brain research 1975;86(3):478-82.
1975: Edith G McGeer; K Searl; H C Fibiger
Chemical specificity of dopamine transport in the nigro--neostriatal projection.
Journal of neurochemistry 1975;24(2):283-8.
1974: Patrick L McGeer; Edith G McGeer; V K Singh; W H Chase
Choline acetyltransferase localization in the central nervous system by immunohistochemistry.
Brain research 1974;81(2):373-9.
1974: Patrick L McGeer; D S Grewaal; Edith G McGeer
Influence of noncholinergic drugs on rat striatal acetylcholine levels.
Brain research 1974;80(2):211-7.
1974: D S Grewaal; H C Fibiger; Edith G McGeer
6-Hydroxydopamine and striatal acetylcholine levels.
Brain research 1974;73(2):372-5.
1974: H C Fibiger; Edith G McGeer
Accumulation and axoplasmic transport of dopamine but not of amino acids by axons of the nigro-neostriatal projection.
Brain research 1974;72(2):366-9.
1974: Edith G McGeer; L Maler; R C Fitzsimmons
Comparative enzymatic development in chick embryonic brain areas.
Developmental biology 1974;38(1):165-74.
1974: Patrick L McGeer; H C Fibiger; L Maler; T Hattori; Edith G McGeer
Evidence for descending pallido-nigral GABA-containing neurons.
Advances in neurology 1974;5():153-60.
1974: V K Singh; H C Fibiger; Edith G McGeer; Patrick L McGeer
Analysis of proteins undergoing axonal transport in nigro-striatal neurons in the rat.
Journal of neurochemistry 1974;22(1):119-24.
1973: H C Fibiger; Edith G McGeer
Increased acoplasmic transport of H3-dopamine in nigro-neostriatal neurons after reserpine.
Life sciences 1973;13(11):1565-71.
1973: Patrick L McGeer; Edith G McGeer; H C Fibiger
Glutamic-acid decarboxylase and choline acetylase in Huntington's chorea and Parkinson's disease.
Lancet 1973;2(7829):622-3.
1973: Patrick L McGeer; Edith G McGeer; H C Fibiger
Choline acetylase and glutamic acid decarboxylase in Huntington's chorea. A preliminary study.
Neurology 1973;23(9):912-7.
1973: H C Fibiger; Edith G McGeer; S Atmadja
Axoplasmic transport of dopamine in nigro-striatal neurons.
Journal of neurochemistry 1973;21(2):373-85.
1973: M E Corcoran; H C Fibiger; Edith G McGeer; J A Wada
Potentiation of leptazol seizures by 6-hydroxydopamine.
The Journal of pharmacy and pharmacology 1973;25(6):497-9.
1973: H C Fibiger; A P Zis; Edith G McGeer
Feeding and drinking deficits after 6-hydroxydopamine administration in the rat: similarities to the lateral hypothalamic syndrome.
Brain research 1973;55(1):135-48.
1973: T Hattori; Patrick L McGeer; H C Fibiger; Edith G McGeer
On the source of GABA-containing terminals in the substantia nigra. Electron microscopic autoradiographic and biochemical studies.
Brain research 1973;54():103-14.
1973: Edith G McGeer; H C Fibiger; Patrick L McGeer; S Brooke
Temporal changes in amine synthesizing enzymes of rat extrapyramidal structures after hemitransections or 6-hydroxydopamine administration.
Brain research 1973;52():289-300.
1973: Patrick L McGeer; Edith G McGeer
Neurotransmitter synthetic enzymes.
Progress in neurobiology 1973;2(1):69-117.
1972: H C Fibiger; R E Pudritz; Patrick L McGeer; Edith G McGeer
Axonal transport in nigro-striatal and nigro-thalamic neurons: effects of medial forebrain bundle lesions and 6-hydroxydopamine.
Journal of neurochemistry 1972;19(7):1697-708.
1972: H C Fibiger; R E Pudritz; Patrick L McGeer; Edith G McGeer
Axonal transport in nigro-striatal neurones.
Nature: New biology 1972;237(75):177-9.
1972: Edith G McGeer; H C Fibiger; Patrick L McGeer
Brain enzymes in amantadine-treated rats.
Biochemical medicine 1972;6(2):189-91.
1972: Patrick L McGeer; L Zeldowicz; Edith G McGeer
A clinical trial of folic acid in Parkinson's disease.
Canadian Medical Association journal 1972;106(2):145-6 passim.
1971: Patrick L McGeer; Edith G McGeer; H C Fibiger; V Wickson
Neostriatal choline acetylase and cholinesterase following selective brain lesions.
Brain research 1971;35(1):308-14.
1971: Edith G McGeer; H C Fibiger; Patrick L McGeer; V Wickson
Aging and brain enzymes.
Experimental gerontology 1971;6(6):391-6.
1971: Patrick L McGeer; Edith G McGeer; J A Wada
Glutamic acid decarboxylase in Parkinson's disease and epilepsy.
Neurology 1971;21(10):1000-7.
1971: Edith G McGeer; H C Fibiger; V Wickson
Differential development of caudate enzymes in the neonatal rat.
Brain research 1971;32(2):433-40.
1971: Patrick L McGeer; Edith G McGeer; J A Wada; E Jung
Effects of globus pallidus lesions and Parkinson's disease on brain glutamic acid decarboxylase.
Brain research 1971;32(2):425-31.
1971: Edith G McGeer; Patrick L McGeer; J A Wada
Distribution of tyrosine hydroxylase in human and animal brain.
Journal of neurochemistry 1971;18(9):1647-58.
1971: H C Fibiger; M Fox; Edith G McGeer; Patrick L McGeer
The effect of amantadine on spontaneous locomotor activity in the rat.
The Journal of pharmacy and pharmacology 1971;23(9):724-5.
1971: Patrick L McGeer; Edith G McGeer
Cholinergic enzyme systems in Parkinson's disease.
Archives of neurology 1971;25(3):265-8.
1970: A Chalmers; Edith G McGeer; V Wickson; Patrick L McGeer
Distribution of glutamic acid decarboxylase in the brains of various mammalian species.
Comparative and general pharmacology 1970;1(4):385-90.
1970: S Gibson; Edith G McGeer; Patrick L McGeer
Effect of selective inhibitors of tyrosine and tryptophan hydroxylases on self-stimulation in the rat.
Experimental neurology 1970;27(2):283-90.
1970: Edith G McGeer
Gelatin capsules as disposable wells for 14-CO2 absorption.
Analytical biochemistry 1970;35(1):300-1.
1969: S Gibson; Edith G McGeer; Patrick L McGeer
Metabolism of catecholamines in cold-exposed rats.
Journal of neurochemistry 1969;16(10):1491-3.
1969: Edith G McGeer; H Ikeda; T Asakura; J A Wada
Lack of abnormality in brain aromatic amines in rats and mice susceptible to audiogenic seizure.
Journal of neurochemistry 1969;16(3):945-50.
1969: L J Poirier; Edith G McGeer; L Larochelle; Patrick L McGeer; P Bedard; R Boucher
The effect of brain stem lesions on tyrosine and tryptophan hydroxylases in various structures of the telencephalon of the cat.
Brain research 1969;14(1):147-55.
1969: Edith G McGeer; J A Wada; A Terao; E Jung
Amine synthesis in various brain regions with caudate or septal lesions.
Experimental neurology 1969;24(2):277-84.
1969: Edith G McGeer; D A Peters
In vitro screen of inhibitors of rat brain serotonin synthesis.
Canadian journal of biochemistry 1969;47(5):501-6.
1968: D A Peters; Patrick L McGeer; Edith G McGeer
The distribution of tryptophan hydroxylase in cat brain.
Journal of neurochemistry 1968;15(12):1431-5.
1968: Edith G McGeer; D A Peters; Patrick L McGeer
Inhibition of rat brain tryptophan hydroxylase by 6-halotryptophans.
Life sciences 1968;7(12):605-15.
1967: Edith G McGeer; S Gibson; J A Wada; Patrick L McGeer
Distribution of tyrosine hydroxylase activity in adult and developing brain.
Canadian journal of biochemistry 1967;45(12):1943-52.
1967: Edith G McGeer; Patrick L McGeer; D A Peters
Inhibition of brain tyrosine hydroxylase by 5-halotryptophans.
Life sciences 1967;6(20):2221-32.
1967: Edith G McGeer; S Gibson; Patrick L McGeer
Some characteristics of brain tyrosine hydroxylase.
Canadian journal of biochemistry 1967;45(10):1557-63.
1967: J A Wada; H Ikeda; Edith G McGeer
The susceptibility to audiogenic stimuli of rats treated with methionine sulfoximine and various psychoactive agents.
Experimental neurology 1967;18(3):327-37.
1966: Edith G McGeer; Patrick L McGeer
Circadian rhythm in pineal tyrosine hydroxylase.
Science (New York, N.Y.) 1966;153(3731):73-4.
1966: J A Wada; Edith G McGeer
Central aromatic amines and behavior. III. Correlative analysis of conditioned approach behavior and brain levels of serotonin and catecholamines in monkeys.
Archives of neurology 1966;14(2):129-42.
1965: Patrick L McGeer; S P Bagchi; Edith G McGeer
Subcellular localization of tyrosine hydroxylase in beef caudate nucleus.
Life sciences 1965;4(19):1859-67.
1964: C O HEBB; G M LING; Edith G McGeer; Patrick L McGeer; D PERKINS
EFFECT OF LOCALLY APPLIED HEMICHOLINIUM ON THE ACETYLCHOLINE CONTENT OF THE CAUDATE NUCLEUS.
Nature 1964;204():1309-11.
1964: Edith G McGeer; W H CLARK
RF VALUES OF SOME CATECHOLAMINES, PRECURSORS AND METABOLITES.
Journal of chromatography 1964;13():107-11.
1963: J A WADA; J WRINCH; D HILL; Patrick L McGeer; Edith G McGeer
Central aromatic amine levels and behavior. I. Conditioned avoidance response in cats, following administration of psychoactive drugs or amine precursors.
Archives of neurology 1963;9():69-80.
1963: N T IYER; P L McGEEER; Edith G McGeer
Conversion of typrosine to catecholamines by rat brain slices.
Canadian journal of biochemistry and physiology 1963;41():1565-70.
1962: B TISCHLER; Edith G McGeer
Effects of folic acid on the phenylalanine tolerance test in phenylketonuria.
Canadian Medical Association journal 1962;87():1331-2.
1961: Patrick L McGeer; Edith G McGeer; R Hasselback
Preliminary Survey of 4-Amino-5-Imidazolecarboxamide Excretion in Leukemia and Other Illnesses.
Canadian Medical Association journal 1961;85(8):437-9.
1961: Patrick L McGeer; Edith G McGeer; A J Wood
Excretion of 4-Amino-5-Imidazolecarboxamide by Various Animal Species.
Canadian journal of comparative medicine and veterinary science 1961;25(8):211-2.
1961: B TISCHLER; W C GIBSON; Edith G McGeer; J NUTTALL
Degrees of mental retardation in phenylketonuria.
American journal of mental deficiency 1961;65():726-38.
1961: Edith G McGeer; M C ROBERTSON; Patrick L McGeer
Chromatographic characteristics of some aromatic compounds of biological interest.
Canadian journal of biochemistry and physiology 1961;39():605-27.
1959: D M SMITH; R M PAUL; Edith G McGeer; Patrick L McGeer
A general chromatographic survey of aromatic compounds obtained from urine.
Canadian journal of biochemistry and physiology 1959;37():1493-515.
1959: Edith G McGeer; B TISCHLER
Vitamin B6 and mental deficiency; the effects of large doses of B6 (pyridoxine) in phenylketonuria.
Canadian journal of biochemistry and physiology 1959;37(3):485-91.
1959: Edith G McGeer; Patrick L McGeer
Physiological effects of schizophrenic body fluids.
The Journal of mental science 1959;105(438):1-18.
1958: B TISCHLER; Edith G McGeer
Vitamin B6 in mental deficiency: xanthurenic acid excretion in phenylketonurics.
Canadian Medical Association journal 1958;78(12):954-5.
1957: Edith G McGeer; W T BROWN; Patrick L McGeer
Aromatic metabolism in schizophrenia. II. Bidimensional urinary chromatograms.
The Journal of nervous and mental disease 1957;125(2):176-80.
1957: Patrick L McGeer; F E McNAIR; Edith G McGeer; W C GIBSON
Aromatic metabolism in schizophrenia. I. Statistical evidence for aromaturia.
The Journal of nervous and mental disease 1957;125(2):166-75.
1956: Patrick L McGeer; Edith G McGeer; J E BOULDING
Relation of aromatic amino acids to excretory pattern of schizophrenics.
Science (New York, N.Y.) 1956;123(3207):1078-80.
1956: Patrick L McGeer; Edith G McGeer; W C GIBSON
Aromatic excretory pattern of schizophrenics.
Science (New York, N.Y.) 1956;123(3206):1029-30.