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William McGinnis

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Rachel A Patterson; Roman Sasik; Hardiman Gary; Anita Hermann; Michelle T Juarez; William McGinnis
Serine proteolytic pathway activation reveals an expanded ensemble of wound response genes in Drosophila.
Adam Christopher Pare; Stuart Brody; Michelle T Juarez; Myungjin Kim; William McGinnis
The functions of grainy head-like proteins in animals and fungi and the evolution of apical extracellular barriers.
Derek Lemons; Adam Christopher Pare; William McGinnis
Three Drosophila Hox complex microRNAs do not have major effects on expression of evolutionarily conserved Hox gene targets during embryogenesis.

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All Publications

2013: Rachel A Patterson; Roman Sasik; Hardiman Gary; Anita Hermann; Michelle T Juarez; William McGinnis
Serine proteolytic pathway activation reveals an expanded ensemble of wound response genes in Drosophila.
PloS one 2013;8(4):e61773.
2012: Adam Christopher Pare; Stuart Brody; Michelle T Juarez; Myungjin Kim; William McGinnis
The functions of grainy head-like proteins in animals and fungi and the evolution of apical extracellular barriers.
PloS one 2012;7(5):e36254.
2012: Derek Lemons; Adam Christopher Pare; William McGinnis
Three Drosophila Hox complex microRNAs do not have major effects on expression of evolutionarily conserved Hox gene targets during embryogenesis.
PloS one 2012;7(2):e31365.
2011: Peter McHale; Claudia Mieko Mizutani; David Kosman; Danielle L MacKay; William McGinnis; Mirela Belu; Ethan Bier; Anita Hermann; Terence Hwa
Gene length may contribute to graded transcriptional responses in the Drosophila embryo.
Developmental biology 2011;360(1):230-40.
2011: Myungjin Kim; William McGinnis
Phosphorylation of Grainy head by ERK is essential for wound-dependent regeneration but not for development of an epidermal barrier.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(2):650-5.
2010: Derek Lemons; Jens H Fritzenwanker; John Gerhart; Christopher J Lowe; William McGinnis
Co-option of an anteroposterior head axis patterning system for proximodistal patterning of appendages in early bilaterian evolution.
Developmental biology 2010;344(1):358-62.
2010: Cheryl C Hsia; Adam Christopher Pare; Michael Hannon; Matthew Ronshaugen; William McGinnis
Silencing of an abdominal Hox gene during early development is correlated with limb development in a crustacean trunk.
Evolution & development 2010;12(2):131-43.
2009: Adam Christopher Pare; Derek Lemons; David Kosman; William Beaver; Yoav Freund; William McGinnis
Visualization of individual Scr mRNAs during Drosophila embryogenesis yields evidence for transcriptional bursting.
Current biology : CB 2009;19(23):2037-42.
2009: Joseph C Pearson; Michelle T Juarez; Myungjin Kim; Øyvind Drivenes; William McGinnis
Multiple transcription factor codes activate epidermal wound-response genes in Drosophila.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(7):2224-9.
2008: Ouarda Taghli-Lamallem; Cheryl Hsia; Matthew Ronshaugen; William McGinnis
Context-dependent regulation of Hox protein functions by CK2 phosphorylation sites.
Development genes and evolution 2008;218(6):321-32.
2006: Derek Lemons; William McGinnis
Genomic evolution of Hox gene clusters.
Science (New York, N.Y.) 2006;313(5795):1918-22.
2006: Ella Tour; William McGinnis
Gap peptides: A new way to control embryonic patterning?
Cell 2006;126(3):448-9.
2005: Joseph C Pearson; Derek Lemons; William McGinnis
Modulating Hox gene functions during animal body patterning.
Nature reviews. Genetics 2005;6(12):893-904.
2005: Ella Tour; Chris Todd Hittinger; William McGinnis
Evolutionarily conserved domains required for activation and repression functions of the Drosophila Hox protein Ultrabithorax.
Development (Cambridge, England) 2005;132(23):5271-81.
2005: Kimberly A Mace; Joseph C Pearson; William McGinnis
An epidermal barrier wound repair pathway in Drosophila is mediated by grainy head.
Science (New York, N.Y.) 2005;308(5720):381-5.
2004: David Kosman; Claudia Mieko Mizutani; Derek Lemons; W Gregory Cox; William McGinnis; Ethan Bier
Multiplex detection of RNA expression in Drosophila embryos.
Science (New York, N.Y.) 2004;305(5685):846.
2003: Cheryl C Hsia; William McGinnis
Evolution of transcription factor function.
Current opinion in genetics & development 2003;13(2):199-206.
2002: Matthew Ronshaugen; Nadine McGinnis; Diane Inglis; Debbie Chou; Jack Zhao; William McGinnis
Structure and expression patterns of Drosophila TULP and TUSP, members of the tubby-like gene family.
Mechanisms of development 2002;117(1-2):209-15.
2002: Ingrid Lohmann; Nadine McGinnis; Morana Bodmer; William McGinnis
The Drosophila Hox gene deformed sculpts head morphology via direct regulation of the apoptosis activator reaper.
Cell 2002;110(4):457-66.
2002: Ingrid Lohmann; William McGinnis
Hox Genes: it's all a matter of context.
Current biology : CB 2002;12(15):R514-6.
2002: Alexey Veraksa; James Kennison; William McGinnis
DEAF-1 function is essential for the early embryonic development of Drosophila.
Genesis (New York, N.Y. : 2000) 2002;33(2):67-76.
2002: Matthew Ronshaugen; Nadine McGinnis; William McGinnis
Hox protein mutation and macroevolution of the insect body plan.
Nature 2002;415(6874):914-7.
2000: J A Pederson; J W LaFollette; C Gross; Alexey Veraksa; William McGinnis; James W Mahaffey
Regulation by homeoproteins: a comparison of deformed-responsive elements.
Genetics 2000;156(2):677-86.
2000: Alexey Veraksa; Nadine McGinnis; Xiaodong Li; J Mohler; William McGinnis
Cap 'n' collar B cooperates with a small Maf subunit to specify pharyngeal development and suppress deformed homeotic function in the Drosophila head.
Development (Cambridge, England) 2000;127(18):4023-37.
2000: Uwe Walldorf; A Kiewe; M Wickert; Matthew Ronshaugen; William McGinnis
Homeobrain, a novel paired-like homeobox gene is expressed in the Drosophila brain.
Mechanisms of development 2000;96(1):141-4.
2000: Alexey Veraksa; M del Campo; William McGinnis
Developmental patterning genes and their conserved functions: from model organisms to humans.
Molecular genetics and metabolism 2000;69(2):85-100.
1999: Xiaodong Li; Alexey Veraksa; William McGinnis
A sequence motif distinct from Hox binding sites controls the specificity of a Hox response element.
Development (Cambridge, England) 1999;126(24):5581-9.
1999: E L Wiellette; K W Harding; K A Mace; Matthew Ronshaugen; F Y Wang; William McGinnis
spen encodes an RNP motif protein that interacts with Hox pathways to repress the development of head-like sclerites in the Drosophila trunk.
Development (Cambridge, England) 1999;126(23):5373-85.
1999: M del Campo; M C Jones; Alexey Veraksa; Cynthia J R Curry; Kenneth Lyons Jones; JT Mascarello; Z Ali-Kahn-Catts; T Drumheller; William McGinnis
Monodactylous limbs and abnormal genitalia are associated with hemizygosity for the human 2q31 region that includes the HOXD cluster.
American journal of human genetics 1999;65(1):104-10.
1999: X Li; William McGinnis
Activity regulation of Hox proteins, a mechanism for altering functional specificity in development and evolution.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(12):6802-7.
1999: E L Wiellette; William McGinnis
Hox genes differentially regulate Serrate to generate segment-specific structures.
Development (Cambridge, England) 1999;126(9):1985-95.
1999: X Li; Cornelis Murre; William McGinnis
Activity regulation of a Hox protein and a role for the homeodomain in inhibiting transcriptional activation.
The EMBO journal 1999;18(1):198-211.
1998: B Florence; William McGinnis
A genetic screen of the Drosophila X chromosome for mutations that modify Deformed function.
Genetics 1998;150(4):1497-511.
1998: Nadine McGinnis; E Ragnhildstveit; Alexey Veraksa; William McGinnis
A cap 'n' collar protein isoform contains a selective Hox repressor function.
Development (Cambridge, England) 1998;125(22):4553-64.
1998: G Gellon; William McGinnis
Shaping animal body plans in development and evolution by modulation of Hox expression patterns.
BioEssays : news and reviews in molecular, cellular and developmental biology 1998;20(2):116-25.
1997: Kenjiro Kosaki; Matthew J McGinniss; Alexey Veraksa; William McGinnis; Kenneth Lyons Jones
Prader-Willi and Angelman syndromes: diagnosis with a bisulfite-treated methylation-specific PCR method.
American journal of medical genetics 1997;73(3):308-13.
1997: Mark D Biggin; William McGinnis
Regulation of segmentation and segmental identity by Drosophila homeoproteins: the role of DNA binding in functional activity and specificity.
Development (Cambridge, England) 1997;124(22):4425-33.
1997: G Gellon; K W Harding; Nadine McGinnis; M M Martin; William McGinnis
A genetic screen for modifiers of Deformed homeotic function identifies novel genes required for head development.
Development (Cambridge, England) 1997;124(17):3321-31.
1997: Julia K Pinsonneault; B Florence; Harald Vaessin; William McGinnis
A model for extradenticle function as a switch that changes HOX proteins from repressors to activators.
The EMBO journal 1997;16(8):2032-42.
1996: C T Gross; William McGinnis
DEAF-1, a novel protein that binds an essential region in a Deformed response element.
The EMBO journal 1996;15(8):1961-70.
1995: C E Vanario-Alonso; E O'Hara; William McGinnis; Leslie Pick
Targeted ribozymes reveal a conserved function of the Drosophila paired gene in sensory organ development.
Mechanisms of development 1995;53(3):323-8.
1995: L Lou; Clare M Bergson; William McGinnis
Deformed expression in the Drosophila central nervous system is controlled by an autoactivated intronic enhancer.
Nucleic acids research 1995;23(17):3481-7.
1995: K W Harding; G Gellon; Nadine McGinnis; William McGinnis
A screen for modifiers of Deformed function in Drosophila.
Genetics 1995;140(4):1339-52.
1994: William McGinnis
A century of homeosis, a decade of homeoboxes.
Genetics 1994;137(3):607-11.
1994: C Zeng; Julia K Pinsonneault; G Gellon; Nadine McGinnis; William McGinnis
Deformed protein binding sites and cofactor binding sites are required for the function of a small segment-specific regulatory element in Drosophila embryos.
The EMBO journal 1994;13(10):2362-77.
1993: J Malicki; L D Bogarad; M M Martin; Frank H Ruddle; William McGinnis
Functional analysis of the mouse homeobox gene HoxB9 in Drosophila development.
Mechanisms of development 1993;42(3):139-50.
1993: E O'Hara; B Cohen; S M Cohen; William McGinnis
Distal-less is a downstream gene of Deformed required for ventral maxillary identity.
Development (Cambridge, England) 1993;117(3):847-56.
1993: B Jones; William McGinnis
A new Drosophila homeobox gene, bsh, is expressed in a subset of brain cells during embryogenesis.
Development (Cambridge, England) 1993;117(2):793-806.
1993: B Jones; William McGinnis
The regulation of empty spiracles by Abdominal-B mediates an abdominal segment identity function.
Genes & development 1993;7(2):229-40.
1992: J Malicki; L C Cianetti; C Peschle; William McGinnis
A human HOX4B regulatory element provides head-specific expression in Drosophila embryos.
Nature 1992;358(6384):345-7.
1992: L Lin; William McGinnis
Mapping functional specificity in the Dfd and Ubx homeo domains.
Genes & development 1992;6(6):1071-81.
1992: S Dessain; C T Gross; M A Kuziora; William McGinnis
Antp-type homeodomains have distinct DNA binding specificities that correlate with their different regulatory functions in embryos.
The EMBO journal 1992;11(3):991-1002.
1992: William McGinnis; R Krumlauf
Homeobox genes and axial patterning.
Cell 1992;68(2):283-302.
1991: S Dessain; William McGinnis
Regulating the expression and function of homeotic genes.
Current opinion in genetics & development 1991;1(2):275-82.
1991: M Regulski; S Dessain; Nadine McGinnis; William McGinnis
High-affinity binding sites for the Deformed protein are required for the function of an autoregulatory enhancer of the Deformed gene.
Genes & development 1991;5(2):278-86.
1991: M Barad; Adrian Erlebacher; William McGinnis
Despite expression in embryonic visceral mesoderm, H2.0 is not essential for Drosophila visceral muscle morphogenesis.
Developmental genetics 1991;12(3):206-11.
1990: M A Kuziora; William McGinnis
Altering the regulatory targets of the Deformed protein in Drosophila embryos by substituting the Abdominal-B homeodomain.
Mechanisms of development 1990;33(1):83-93.
1990: Clare M Bergson; William McGinnis
An autoregulatory enhancer element of the Drosophila homeotic gene Deformed.
The EMBO journal 1990;9(13):4287-97.
1990: Nadine McGinnis; M A Kuziora; William McGinnis
Human Hox-4.2 and Drosophila deformed encode similar regulatory specificities in Drosophila embryos and larvae.
Cell 1990;63(5):969-76.
1990: J Malicki; K Schughart; William McGinnis
Mouse Hox-2.2 specifies thoracic segmental identity in Drosophila embryos and larvae.
Cell 1990;63(5):961-7.
1990: R Chadwick; B Jones; T Jack; William McGinnis
Ectopic expression from the Deformed gene triggers a dominant defect in Drosophila adult head development.
Developmental biology 1990;141(1):130-40.
1990: T Jack; William McGinnis
Establishment of the Deformed expression stripe requires the combinatorial action of coordinate, gap and pair-rule proteins.
The EMBO journal 1990;9(4):1187-98.
1990: William McGinnis; T Jack; R Chadwick; M Regulski; Clare M Bergson; Nadine McGinnis; M A Kuziora
Establishment and maintenance of position-specific expression of the Drosophila homeotic selector gene Deformed.
Advances in genetics 1990;27():363-402.
1989: D Dalton; R Chadwick; William McGinnis
Expression and embryonic function of empty spiracles: a Drosophila homeo box gene with two patterning functions on the anterior-posterior axis of the embryo.
Genes & development 1989;3(12A):1940-56.
1989: M A Kuziora; William McGinnis
A homeodomain substitution changes the regulatory specificity of the deformed protein in Drosophila embryos.
Cell 1989;59(3):563-71.
1988: M A Kuziora; William McGinnis
Autoregulation of a Drosophila homeotic selector gene.
Cell 1988;55(3):477-85.
1988: M A Kuziora; William McGinnis
Different transcripts of the Drosophila Abd-B gene correlate with distinct genetic sub-functions.
The EMBO journal 1988;7(10):3233-44.
1988: M Barad; T Jack; R Chadwick; William McGinnis
A novel, tissue-specific, Drosophila homeobox gene.
The EMBO journal 1988;7(7):2151-61.
1987: R Chadwick; William McGinnis
Temporal and spatial distribution of transcripts from the Deformed gene of Drosophila.
The EMBO journal 1987;6(3):779-89.
1987: M Regulski; Nadine McGinnis; R Chadwick; William McGinnis
Developmental and molecular analysis of Deformed; a homeotic gene controlling Drosophila head development.
The EMBO journal 1987;6(3):767-77.
1985: M Regulski; K Harding; R Kostriken; F Karch; M Levine; William McGinnis
Homeo box genes of the Antennapedia and bithorax complexes of Drosophila.
Cell 1985;43(1):71-80.