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Richard McIntosh

Research Profile

Anatomy

Concepts & Ideas

Chemicals & Drugs

Procedures

Microscopy, Electron

Living Beings

Schizosaccharomyces

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Vladimir Volkov; Anatoly V Zaytsev; Fazoil I Ataullakhanov; Alexander L Gintsburg; Paula M Grissom; Nikita Gudimchuk; J Richard McIntosh; Ekaterina L Grishchuk
Long tethers provide high-force coupling of the Dam1 ring to shortening microtubules.
J Richard McIntosh; Mary K Morphew; Eileen T O'Toole; Cindi Schwartz; Kirill Zhudenkov; Fazly I Ataullakhanov; Ekaterina L Grishchuk
Conserved and divergent features of kinetochores and spindle microtubule ends from five species.
J Richard McIntosh
Motors or dynamics: what really moves chromosomes?

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2013: Vladimir Volkov; Anatoly V Zaytsev; Fazoil I Ataullakhanov; Alexander L Gintsburg; Paula M Grissom; Nikita Gudimchuk; J Richard McIntosh; Ekaterina L Grishchuk
Long tethers provide high-force coupling of the Dam1 ring to shortening microtubules.
Proceedings of the National Academy of Sciences of the United States of America 2013;110(19):7708-13.
2013: J Richard McIntosh; Mary K Morphew; Eileen T O'Toole; Cindi Schwartz; Kirill Zhudenkov; Fazly I Ataullakhanov; Ekaterina L Grishchuk
Conserved and divergent features of kinetochores and spindle microtubule ends from five species.
The Journal of cell biology 2013;200(4):459-74.
2012: J Richard McIntosh
Motors or dynamics: what really moves chromosomes?
Nature cell biology 2012;14(12):1234.
2012: J Richard McIntosh; Maxim I Molodtsov; Fazly I Ataullakhanov
Biophysics of mitosis.
Quarterly reviews of biophysics 2012;45(2):147-207.
2012: Johanna L Höög; J Richard McIntosh; Cédric Bouchet-Marquis; Andreas Hoenger; Keith Gull
Cryo-electron tomography and 3-D analysis of the intact flagellum in Trypanosoma brucei.
Journal of structural biology 2012;178(2):189-98.
2011: J Richard McIntosh
Mitosis futures: the past is prologue.
Molecular biology of the cell 2011;22(21):3933-5.
2010: J Richard McIntosh; Vladimir Volkov; Fazoil I Ataullakhanov; Ekaterina L Grishchuk
Tubulin depolymerization may be an ancient biological motor.
Journal of cell science 2010;123(Pt 20):3425-34.
2010: Sylvain Lacomble; Sue Vaughan; Catarina Gadelha; Mary K Morphew; Michael K Shaw; J Richard McIntosh; Keith Gull
Basal body movements orchestrate membrane organelle division and cell morphogenesis in Trypanosoma brucei.
Journal of cell science 2010;123(Pt 17):2884-91.
2009: J Richard McIntosh; Mary K Morphew; Paula M Grissom; Susan P Gilbert; Andreas Hoenger
Lattice structure of cytoplasmic microtubules in a cultured Mammalian cell.
Journal of molecular biology 2009;394(2):177-82.
2009: Catarina Gadelha; Stephen Rothery; Mary Morphew; J Richard McIntosh; Nicholas J Severs; Keith Gull
Membrane domains and flagellar pocket boundaries are influenced by the cytoskeleton in African trypanosomes.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(41):17425-30.
2009: L E Hough; Anne Schwabe; Matthew A Glaser; J Richard McIntosh; Meredith D Betterton
Microtubule depolymerization by the Kinesin-8 motor Kip3p: a mathematical model.
Biophysical journal 2009;96(8):3050-64.
2009: Sylvain Lacomble; Sue Vaughan; Catarina Gadelha; Mary K Morphew; Michael K Shaw; J Richard McIntosh; Keith Gull
Three-dimensional cellular architecture of the flagellar pocket and associated cytoskeleton in trypanosomes revealed by electron microscope tomography.
Journal of cell science 2009;122(Pt 8):1081-90.
2009: G Singh; P Rice; Roop L Mahajan; J Richard McIntosh
Fabrication and characterization of a carbon nanotube-based nanoknife.
Nanotechnology 2009;20(9):095701.
2009: Andreas Hoenger; J Richard McIntosh
Probing the macromolecular organization of cells by electron tomography.
Current opinion in cell biology 2009;21(1):89-96.
2008: J Richard McIntosh; Ekaterina L Grishchuk; Mary K Morphew; Artem K Efremov; Kirill Zhudenkov; Vladimir Volkov; Iain M Cheeseman; Arshad Desai; David N Mastronarde; Fazoil I Ataullakhanov
Fibrils connect microtubule tips with kinetochores: a mechanism to couple tubulin dynamics to chromosome motion.
Cell 2008;135(2):322-33.
2008: Ekaterina L Grishchuk; Artem K Efremov; Vladimir Volkov; Ilia S Spiridonov; Nikita Gudimchuk; Stefan Westermann; David Drubin; Georjana Barnes; J Richard McIntosh; Fazoil I Ataullakhanov
The Dam1 ring binds microtubules strongly enough to be a processive as well as energy-efficient coupler for chromosome motion.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(40):15423-8.
2008: Wanzhong He; Mark S Ladinsky; Kathryn E Huey-Tubman; Grant J Jensen; J Richard McIntosh; Pamela J Björkman
FcRn-mediated antibody transport across epithelial cells revealed by electron tomography.
Nature 2008;455(7212):542-6.
2008: Robert R West; J Richard McIntosh
Novel interactions of fission yeast kinesin 8 revealed through in vivo expression of truncation alleles.
Cell motility and the cytoskeleton 2008;65(8):626-40.
2008: Ekaterina L Grishchuk; I S Spiridonov; Vladimir Volkov; A Efremov; S Westermann; D Drubin; G Barnes; Fazoil I Ataullakhanov; J Richard McIntosh
Different assemblies of the DAM1 complex follow shortening microtubules by distinct mechanisms.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(19):6918-23.
2008: Mary K Morphew; W He; Pamela J Bjorkman; J Richard McIntosh
Silver enhancement of Nanogold particles during freeze substitution for electron microscopy.
Journal of microscopy 2008;230(Pt 2):263-7.
2007: Artem Efremov; Ekaterina L Grishchuk; J Richard McIntosh; Fazoil I Ataullakhanov
In search of an optimal ring to couple microtubule depolymerization to processive chromosome motions.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(48):19017-22.
2007: Patricia Melloy; Shu Shen; Erin White; J Richard McIntosh; Mark D Rose
Nuclear fusion during yeast mating occurs by a three-step pathway.
The Journal of cell biology 2007;179(4):659-70.
2007: Wanzhong He; Christine Kivork; Suman Machinani; Mary K Morphew; Anna M Gail; Devin B Tesar; Noreen E Tiangco; J Richard McIntosh; Pamela J Bjorkman
A freeze substitution fixation-based gold enlarging technique for EM studies of endocytosed Nanogold-labeled molecules.
Journal of structural biology 2007;160(1):103-13.
2007: Cindi L Schwartz; Vasily I Sarbash; Fazoil I Ataullakhanov; J Richard McIntosh; Daniela Nicastro
Cryo-fluorescence microscopy facilitates correlations between light and cryo-electron microscopy and reduces the rate of photobleaching.
Journal of microscopy 2007;227(Pt 2):98-109.
2007: Ekaterina L Grishchuk; Ilia S Spiridonov; J Richard McIntosh
Mitotic chromosome biorientation in fission yeast is enhanced by dynein and a minus-end-directed, kinesin-like protein.
Molecular biology of the cell 2007;18(6):2216-25.
2007: Johanna Louise Hoog; Cindi Schwartz; Angela T Noon; Eileen T O'Toole; David N Mastronarde; J Richard McIntosh; Claude Antony
Organization of interphase microtubules in fission yeast analyzed by electron tomography.
Developmental cell 2007;12(3):349-61.
2007: Maxim I Molodtsov; Ekaterina L Grishchuk; J Richard McIntosh; Fazoil I Ataullakhanov
Measurement of the force developed by disassembling microtubule during calcium-induced depolymerization.
Doklady. Biochemistry and biophysics 2007;412():18-21.
2006: Mark S Ladinsky; Jason M Pierson; J Richard McIntosh
Vitreous cryo-sectioning of cells facilitated by a micromanipulator.
Journal of microscopy 2006;224(Pt 2):129-34.
2006: Olga S Fedyanina; Pavel V Mardanov; Ekaterina M Tokareva; J Richard McIntosh; Ekaterina L Grishchuk
Chromosome segregation in fission yeast with mutations in the tubulin folding cofactor D.
Current genetics 2006;50(5):281-94.
2006: Ekaterina L Grishchuk; J Richard McIntosh
Microtubule depolymerization can drive poleward chromosome motion in fission yeast.
The EMBO journal 2006;25(20):4888-96.
2006: Daniela Nicastro; Cindi Schwartz; Jason Pierson; Richard Gaudette; Mary E Porter; J Richard McIntosh
The molecular architecture of axonemes revealed by cryoelectron tomography.
Science (New York, N.Y.) 2006;313(5789):944-8.
2005: Ekaterina L Grishchuk; Maxim I Molodtsov; Fazoil I Ataullakhanov; J Richard McIntosh
Force production by disassembling microtubules.
Nature 2005;438(7066):384-8.
2005: K Kevin Pfister; Elizabeth M C Fisher; Ian R Gibbons; Thomas S Hays; Erika L F Holzbaur; J Richard McIntosh; Mary E Porter; Trina A Schroer; Kevin T Vaughan; George B Witman; Stephen M King; Richard B Vallee
Cytoplasmic dynein nomenclature.
The Journal of cell biology 2005;171(3):411-3.
2005: Daniela Nicastro; J Richard McIntosh; Wolfgang Baumeister
3D structure of eukaryotic flagella in a quiescent state revealed by cryo-electron tomography.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(44):15889-94.
2005: Maxim I Molodtsov; Elena A Ermakova; Emmanuil E Shnol; Ekaterina L Grishchuk; J Richard McIntosh; Fazoil I Ataullakhanov
A molecular-mechanical model of the microtubule.
Biophysical journal 2005;88(5):3167-79.
2005: Maxim I Molodtsov; Ekaterina L Grishchuk; A K Efremov; J Richard McIntosh; Fazoil I Ataullakhanov
Force production by depolymerizing microtubules: a theoretical study.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(12):4353-8.
2005: J Richard McIntosh
Rings around kinetochore microtubules in yeast.
Nature structural & molecular biology 2005;12(3):210-2.
2005: Dewight R Williams; J Richard McIntosh
Mcl1p is a polymerase alpha replication accessory factor important for S-phase DNA damage survival.
Eukaryotic cell 2005;4(1):166-77.
2004: Carolyn J Lawrence; R Kelly Dawe; Karen R Christie; Don W Cleveland; Scott C Dawson; Sharyn A Endow; Lawrence S B Goldstein; Holly V Goodson; Nobutaka Hirokawa; Jonathon Howard; Russell L Malmberg; J Richard McIntosh; Harukata Miki; Timothy J Mitchison; Yasushi Okada; Anireddy S N Reddy; William M Saxton; Manfred Schliwa; Jonathan M Scholey; Ronald D Vale; Claire E Walczak; Linda Wordeman
A standardized kinesin nomenclature.
The Journal of cell biology 2004;167(1):19-22.
2004: Brad J Marsh; Niels Volkmann; J Richard McIntosh; Kathryn E Howell
Direct continuities between cisternae at different levels of the Golgi complex in glucose-stimulated mouse islet beta cells.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(15):5565-70.
2003: Eileen T O'Toole; Kent L McDonald; Jana Mäntler; J Richard McIntosh; Anthony A Hyman; Thomas Müller-Reichert
Morphologically distinct microtubule ends in the mitotic centrosome of Caenorhabditis elegans.
The Journal of cell biology 2003;163(3):451-6.
2003: Mary K Morphew; J Richard McIntosh
The use of filter membranes for high-pressure freezing of cell monolayers.
Journal of microscopy 2003;212(Pt 1):21-5.
2003: Eileen T O'Toole; Thomas H Giddings; J Richard McIntosh; Susan Dutcher
Three-dimensional organization of basal bodies from wild-type and delta-tubulin deletion strains of Chlamydomonas reinhardtii.
Molecular biology of the cell 2003;14(7):2999-3012.
2003: Kristi K H Stanlis; J Richard McIntosh
Single-strand DNA aptamers as probes for protein localization in cells.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2003;51(6):797-808.
2002: Dewight R Williams; J Richard McIntosh
mcl1+, the Schizosaccharomyces pombe homologue of CTF4, is important for chromosome replication, cohesion, and segregation.
Eukaryotic cell 2002;1(5):758-73.
2002: Frances R Putkey; Thorsten Cramer; Mary K Morphew; Alain Silk; Randall S Johnson; J Richard McIntosh; Don W Cleveland
Unstable kinetochore-microtubule capture and chromosomal instability following deletion of CENP-E.
Developmental cell 2002;3(3):351-65.
2002: Mark S Ladinsky; Christine C Wu; Shane McIntosh; J Richard McIntosh; Kathryn E Howell
Structure of the Golgi and distribution of reporter molecules at 20 degrees C reveals the complexity of the exit compartments.
Molecular biology of the cell 2002;13(8):2810-25.
2002: Michael J E Krien; Robert R West; Ulrik P John; Kalli Koniaras; J Richard McIntosh; Matthew O'Connell
The fission yeast NIMA kinase Fin1p is required for spindle function and nuclear envelope integrity.
The EMBO journal 2002;21(7):1713-22.
2002: Paula M Grissom; Eugeni A Vaisberg; J Richard McIntosh
Identification of a novel light intermediate chain (D2LIC) for mammalian cytoplasmic dynein 2.
Molecular biology of the cell 2002;13(3):817-29.
2002: Robert R West; Terra Malmstrom; J Richard McIntosh
Kinesins klp5(+) and klp6(+) are required for normal chromosome movement in mitosis.
Journal of cell science 2002;115(Pt 5):931-40.
2002: J Richard McIntosh; Ekaterina L Grishchuk; Robert R West
Chromosome-microtubule interactions during mitosis.
Annual review of cell and developmental biology 2002;18():193-219.
2002: Eileen T O'Toole; Mark Winey; J Richard McIntosh; David N Mastronarde
Electron tomography of yeast cells.
Methods in enzymology 2002;351():81-95.
2001: Robert R West; T Malmstrom; C L Troxell; J Richard McIntosh
Two related kinesins, klp5+ and klp6+, foster microtubule disassembly and are required for meiosis in fission yeast.
Molecular biology of the cell 2001;12(12):3919-32.
2001: C L Troxell; M A Sweezy; Robert R West; K D Reed; B D Carson; Alison L Pidoux; W Zacheus Cande; J Richard McIntosh
pkl1(+)and klp2(+): Two kinesins of the Kar3 subfamily in fission yeast perform different functions in both mitosis and meiosis.
Molecular biology of the cell 2001;12(11):3476-88.
2001: Barbara Kniola; E O'Toole; J Richard McIntosh; Barbara G Mellone; Robin C Allshire; S Mengarelli; K Hultenby; Karl Ekwall
The domain structure of centromeres is conserved from fission yeast to humans.
Molecular biology of the cell 2001;12(9):2767-75.
2001: Brad J Marsh; David N Mastronarde; J Richard McIntosh; Kathryn E Howell
Structural evidence for multiple transport mechanisms through the Golgi in the pancreatic beta-cell line, HIT-T15.
Biochemical Society transactions 2001;29(Pt 4):461-7.
2001: J Richard McIntosh
Electron microscopy of cells: a new beginning for a new century.
The Journal of cell biology 2001;153(6):F25-32.
2001: Brad J Marsh; David N Mastronarde; K F Buttle; Kathryn E Howell; J Richard McIntosh
Organellar relationships in the Golgi region of the pancreatic beta cell line, HIT-T15, visualized by high resolution electron tomography.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(5):2399-406.
2001: Thomas H Giddings; Eileen T O'Toole; Mary K Morphew; David N Mastronarde; J Richard McIntosh; Mark Winey
Using rapid freeze and freeze-substitution for the preparation of yeast cells for electron microscopy and three-dimensional analysis.
Methods in cell biology 2001;67():27-42.
2000: Heidi Browning; Jacqueline Hayles; Juan Mata; L Aveline; Paul Nurse; J Richard McIntosh
Tea2p is a kinesin-like protein required to generate polarized growth in fission yeast.
The Journal of cell biology 2000;151(1):15-28.
2000: J K Yucel; J D Marszalek; J Richard McIntosh; Lawrence S B Goldstein; Don W Cleveland; alastair philp
CENP-meta, an essential kinetochore kinesin required for the maintenance of metaphase chromosome alignment in Drosophila.
The Journal of cell biology 2000;150(1):1-11.
1999: X Zeng; J A Kahana; P A Silver; Mary K Morphew; J Richard McIntosh; I T Fitch; J Carbon; William S Saunders
Slk19p is a centromere protein that functions to stabilize mitotic spindles.
The Journal of cell biology 1999;146(2):415-25.
1999: Ayumu Yamamoto; Robert R West; J Richard McIntosh; Yasushi Hiraoka
A cytoplasmic dynein heavy chain is required for oscillatory nuclear movement of meiotic prophase and efficient meiotic recombination in fission yeast.
The Journal of cell biology 1999;145(6):1233-49.
1999: E T O'Toole; Mark Winey; J Richard McIntosh
High-voltage electron tomography of spindle pole bodies and early mitotic spindles in the yeast Saccharomyces cerevisiae.
Molecular biology of the cell 1999;10(6):2017-31.
1999: Ekaterina L Grishchuk; J Richard McIntosh
Sto1p, a fission yeast protein similar to tubulin folding cofactor E, plays an essential role in mitotic microtubule assembly.
Journal of cell science 1999;112 ( Pt 12)():1979-88.
1999: J Richard McIntosh; E T O'Toole
Life cycles of yeast spindle pole bodies: getting microtubules into a closed nucleus.
Biology of the cell / under the auspices of the European Cell Biology Organization 1999;91(4-5):305-12.
1999: Mark S Ladinsky; David N Mastronarde; J Richard McIntosh; Kathryn E Howell; L Andrew Staehelin
Golgi structure in three dimensions: functional insights from the normal rat kidney cell.
The Journal of cell biology 1999;144(6):1135-49.
1998: G Steinberg; J Richard McIntosh
Effects of the myosin inhibitor 2,3-butanedione monoxime on the physiology of fission yeast.
European journal of cell biology 1998;77(4):284-93.
1998: Caroline R M Wilkinson; Mairi Wallace; Mary K Morphew; Paul Perry; Robin C Allshire; Jean-Paul Javerzat; J Richard McIntosh; Colin Gordon
Localization of the 26S proteasome during mitosis and meiosis in fission yeast.
The EMBO journal 1998;17(22):6465-76.
1998: A J Hunt; J Richard McIntosh
The dynamic behavior of individual microtubules associated with chromosomes in vitro.
Molecular biology of the cell 1998;9(10):2857-71.
1998: Robert R West; E V Vaisberg; R Ding; Paul Nurse; J Richard McIntosh
cut11(+): A gene required for cell cycle-dependent spindle pole body anchoring in the nuclear envelope and bipolar spindle formation in Schizosaccharomyces pombe.
Molecular biology of the cell 1998;9(10):2839-55.
1998: Paul S. Shapiro; Eugeni A Vaisberg; A J Hunt; NS Tolwinski; Anne M Whalen; J Richard McIntosh; Natalie G Ahn
Activation of the MKK/ERK pathway during somatic cell mitosis: direct interactions of active ERK with kinetochores and regulation of the mitotic 3F3/2 phosphoantigen.
The Journal of cell biology 1998;142(6):1533-45.
1998: Gero Steinberg; Manfred Schliwa; C Lehmler; Michael Bölker; Regine Kahmann; J Richard McIntosh
Kinesin from the plant pathogenic fungus Ustilago maydis is involved in vacuole formation and cytoplasmic migration.
Journal of cell science 1998;111 ( Pt 15)():2235-46.
1998: Ekaterina L Grishchuk; J L Howe; J Richard McIntosh
A screen for genes involved in the anaphase proteolytic pathway identifies tsm1(+), a novel Schizosaccharomyces pombe gene important for microtubule integrity.
Genetics 1998;149(3):1251-64.
1997: R Ding; Robert R West; D M Morphew; B R Oakley; J Richard McIntosh
The spindle pole body of Schizosaccharomyces pombe enters and leaves the nuclear envelope as the cell cycle proceeds.
Molecular biology of the cell 1997;8(8):1461-79.
1997: Eileen T O'Toole; David N Mastronarde; Thomas H Giddings; Mark Winey; Daniel J Burke; J Richard McIntosh
Three-dimensional analysis and ultrastructural design of mitotic spindles from the cdc20 mutant of Saccharomyces cerevisiae.
Molecular biology of the cell 1997;8(1):1-11.
1996: J F Mooney; A J Hunt; J Richard McIntosh; C A Liberko; D M Walba; C T Rogers
Patterning of functional antibodies and other proteins by photolithography of silane monolayers.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(22):12287-91.
1996: E A Vaisberg; P M Grissom; J Richard McIntosh
Mammalian cells express three distinct dynein heavy chains that are localized to different cytoplasmic organelles.
The Journal of cell biology 1996;133(4):831-42.
1996: J R Kremer; David N Mastronarde; J Richard McIntosh
Computer visualization of three-dimensional image data using IMOD.
Journal of structural biology 1996;116(1):71-6.
1995: J Richard McIntosh; R R West
A cell biological perspective on genome research.
The Journal of cell biology 1995;131(6 Pt 1):1361-4.
1995: K R Olson; J Richard McIntosh; J B Olmsted
Analysis of MAP 4 function in living cells using green fluorescent protein (GFP) chimeras.
The Journal of cell biology 1995;130(3):639-50.
1995: Mark Winey; C L Mamay; ET O'Toole; David N Mastronarde; Thomas H Giddings; K L McDonald; J Richard McIntosh
Three-dimensional ultrastructural analysis of the Saccharomyces cerevisiae mitotic spindle.
The Journal of cell biology 1995;129(6):1601-15.
1995: V A Lombillo; R J Stewart; J Richard McIntosh
Minus-end-directed motion of kinesin-coated microspheres driven by microtubule depolymerization.
Nature 1995;373(6510):161-4.
1995: V A Lombillo; Corey Nislow; T J Yen; V I Gelfand; J Richard McIntosh
Antibodies to the kinesin motor domain and CENP-E inhibit microtubule depolymerization-dependent motion of chromosomes in vitro.
The Journal of cell biology 1995;128(1-2):107-15.
1995: ET O'Toole; David N Mastronarde; J Richard McIntosh; Mary E Porter
Computer-assisted analysis of flagellar structure.
Methods in cell biology 1995;47():183-91.
1994: M P Koonce; P M Grissom; M Lyon; T Pope; J Richard McIntosh
Molecular characterization of a cytoplasmic dynein from Dictyostelium.
The Journal of eukaryotic microbiology 1994;41(6):645-51.
1994: M S Ladinsky; J R Kremer; P S Furcinitti; J Richard McIntosh; K E Howell
HVEM tomography of the trans-Golgi network: structural insights and identification of a lace-like vesicle coat.
The Journal of cell biology 1994;127(1):29-38.
1994: Thomas Hays; Mary E Porter; M McGrail; P Grissom; P Gosch; Margaret T Fuller; J Richard McIntosh
A cytoplasmic dynein motor in Drosophila: identification and localization during embryogenesis.
Journal of cell science 1994;107 ( Pt 6)():1557-69.
1993: David N Mastronarde; K L McDonald; R Ding; J Richard McIntosh
Interpolar spindle microtubules in PTK cells.
The Journal of cell biology 1993;123(6 Pt 1):1475-89.
1993: E A Vaisberg; M P Koonce; J Richard McIntosh
Cytoplasmic dynein plays a role in mammalian mitotic spindle formation.
The Journal of cell biology 1993;123(4):849-58.
1993: ET O'Toole; G Wray; J Kremer; J Richard McIntosh
High voltage cryomicroscopy of human blood platelets.
Journal of structural biology 1993;110(1):55-66.
1993: R Ding; K L McDonald; J Richard McIntosh
Three-dimensional reconstruction and analysis of mitotic spindles from the yeast, Schizosaccharomyces pombe.
The Journal of cell biology 1993;120(1):141-51.
1993: V A Lombillo; M Coue; J Richard McIntosh
In vitro motility assays using microtubules tethered to Tetrahymena pellicles.
Methods in cell biology 1993;39():149-65.
1992: M P Koonce; P M Grissom; J Richard McIntosh
Dynein from Dictyostelium: primary structure comparisons between a cytoplasmic motor enzyme and flagellar dynein.
The Journal of cell biology 1992;119(6):1597-604.
1992: Corey Nislow; V A Lombillo; Ryoko Kuriyama; J Richard McIntosh
A plus-end-directed motor enzyme that moves antiparallel microtubules in vitro localizes to the interzone of mitotic spindles.
Nature 1992;359(6395):543-7.
1992: David N Mastronarde; ET O'Toole; K L McDonald; J Richard McIntosh; Mary E Porter
Arrangement of inner dynein arms in wild-type and mutant flagella of Chlamydomonas.
The Journal of cell biology 1992;118(5):1145-62.
1992: K L McDonald; ET O'Toole; David N Mastronarde; J Richard McIntosh
Kinetochore microtubules in PTK cells.
The Journal of cell biology 1992;118(2):369-83.
1992: P M Grissom; Mary E Porter; J Richard McIntosh
Two distinct isoforms of sea urchin egg dynein.
Cell motility and the cytoskeleton 1992;21(4):281-92.
1991: J Richard McIntosh; Curt M Pfarr
Mitotic motors.
The Journal of cell biology 1991;115(3):577-85.
1991: Bruce A Molitoris; A Geerdes; J Richard McIntosh
Dissociation and redistribution of Na+,K(+)-ATPase from its surface membrane actin cytoskeletal complex during cellular ATP depletion.
The Journal of clinical investigation 1991;88(2):462-9.
1991: M Coue; V A Lombillo; J Richard McIntosh
Microtubule depolymerization promotes particle and chromosome movement in vitro.
The Journal of cell biology 1991;112(6):1165-75.
1991: J Richard McIntosh
Structural and mechanical control of mitotic progression.
Cold Spring Harbor symposia on quantitative biology 1991;56():613-9.
1991: J Richard McIntosh; G E Hering
Spindle fiber action and chromosome movement.
Annual review of cell biology 1991;7():403-26.
1990: Corey Nislow; C Sellitto; Ryoko Kuriyama; J Richard McIntosh
A monoclonal antibody to a mitotic microtubule-associated protein blocks mitotic progression.
The Journal of cell biology 1990;111(2):511-22.
1990: M M Rozdzial; B W Neighbors; J Richard McIntosh
Blot overlay identification of microtubule-binding peptides from bovine brain.
European journal of cell biology 1990;52(1):27-35.
1990: Curt M Pfarr; M Coue; P M Grissom; Thomas Hays; Mary E Porter; J Richard McIntosh
Cytoplasmic dynein is localized to kinetochores during mitosis.
Nature 1990;345(6272):263-5.
1990: M P Koonce; J Richard McIntosh
Identification and immunolocalization of cytoplasmic dynein in Dictyostelium.
Cell motility and the cytoskeleton 1990;15(1):51-62.
1989: J Richard McIntosh; M P Koonce
Mitosis.
Science (New York, N.Y.) 1989;246(4930):622-8.
1989: J Richard McIntosh; K L McDonald
The mitotic spindle.
Scientific American 1989;261(4):48-56.
1989: J B Olmsted; D L Stemple; William M Saxton; B W Neighbors; J Richard McIntosh
Cell cycle-dependent changes in the dynamics of MAP 2 and MAP 4 in cultured cells.
The Journal of cell biology 1989;109(1):211-23.
1989: J Richard McIntosh; Mary E Porter
Enzymes for microtubule-dependent motility.
The Journal of biological chemistry 1989;264(11):6001-4.
1988: G P Vigers; M Coue; J Richard McIntosh
Fluorescent microtubules break up under illumination.
The Journal of cell biology 1988;107(3):1011-24.
1988: Mary E Porter; P M Grissom; Jonathan M Scholey; E D Salmon; J Richard McIntosh
Dynein isoforms in sea urchin eggs.
The Journal of biological chemistry 1988;263(14):6759-71.
1988: B W Neighbors; R C Williams; J Richard McIntosh
Localization of kinesin in cultured cells.
The Journal of cell biology 1988;106(4):1193-204.
1988: William M Saxton; Mary E Porter; S A Cohn; Jonathan M Scholey; Elizabeth C Raff; J Richard McIntosh
Drosophila kinesin: characterization of microtubule motility and ATPase.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(4):1109-13.
1988: D L Stemple; S C Sweet; Michael J Welsh; J Richard McIntosh
Dynamics of a fluorescent calmodulin analog in the mammalian mitotic spindle at metaphase.
Cell motility and the cytoskeleton 1988;9(3):231-42.
1987: R J Lye; Mary E Porter; J M Scholey; J Richard McIntosh
Identification of a microtubule-based cytoplasmic motor in the nematode C. elegans.
Cell 1987;51(2):309-18.
1987: W M Saxton; J Richard McIntosh
Interzone microtubule behavior in late anaphase and telophase spindles.
The Journal of cell biology 1987;105(2):875-86.
1987: R J Leslie; R B Hird; L Wilson; J Richard McIntosh; J M Scholey
Kinesin is associated with a nonmicrotubule component of sea urchin mitotic spindles.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(9):2771-5.
1987: Mary E Porter; Jonathan M Scholey; D L Stemple; G P Vigers; Ronald D Vale; M P Sheetz; J Richard McIntosh
Characterization of the microtubule movement produced by sea urchin egg kinesin.
The Journal of biological chemistry 1987;262(6):2794-802.
1986: Robley C Williams; Michael Caplow; J Richard McIntosh
Cytoskeleton. Dynamic microtubule dynamics.
Nature 1986;324(6093):106-7.
1986: Lawrence S B Goldstein; R A Laymon; J Richard McIntosh
A microtubule-associated protein in Drosophila melanogaster: identification, characterization, and isolation of coding sequences.
The Journal of cell biology 1986;102(6):2076-87.
1986: J Richard McIntosh; William M Saxton; D L Stemple; R J Leslie; Michael J Welsh
Dynamics of tubulin and calmodulin in the mammalian mitotic spindle.
Annals of the New York Academy of Sciences 1986;466():566-79.
1986: A S Dinenberg; J Richard McIntosh; J M Scholey
Studies on sea urchin egg cytoplasmic ATPases of possible significance for microtubule functions.
Annals of the New York Academy of Sciences 1986;466():431-5.
1985: Jonathan M Scholey; Mary E Porter; P M Grissom; J Richard McIntosh
Identification of kinesin in sea urchin eggs, and evidence for its localization in the mitotic spindle.
Nature 1985;318(6045):483-6.
1985: J Richard McIntosh; U P Roos; B Neighbors; K L McDonald
Architecture of the microtubule component of mitotic spindles from Dictyostelium discoideum.
Journal of cell science 1985;75():93-129.
1985: J Richard McIntosh
Spindle structure and the mechanisms of chromosome movement.
Basic life sciences 1985;36():197-229.
1984: William M Saxton; D L Stemple; R J Leslie; E D Salmon; M Zavortink; J Richard McIntosh
Tubulin dynamics in cultured mammalian cells.
The Journal of cell biology 1984;99(6):2175-86.
1984: E D Salmon; R J Leslie; William M Saxton; M L Karow; J Richard McIntosh
Spindle microtubule dynamics in sea urchin embryos: analysis using a fluorescein-labeled tubulin and measurements of fluorescence redistribution after laser photobleaching.
The Journal of cell biology 1984;99(6):2165-74.
1984: E D Salmon; William M Saxton; R J Leslie; M L Karow; J Richard McIntosh
Diffusion coefficient of fluorescein-labeled tubulin in the cytoplasm of embryonic cells of a sea urchin: video image analysis of fluorescence redistribution after photobleaching.
The Journal of cell biology 1984;99(6):2157-64.
1984: R J Leslie; William M Saxton; T J Mitchison; B Neighbors; E D Salmon; J Richard McIntosh
Assembly properties of fluorescein-labeled tubulin in vitro before and after fluorescence bleaching.
The Journal of cell biology 1984;99(6):2146-56.
1984: J Richard McIntosh
Cell biology. Microtubule catastrophe.
Nature 1984;312(5991):196-7.
1984: J M Scholey; B Neighbors; J Richard McIntosh; E D Salmon
Isolation of microtubules and a dynein-like MgATPase from unfertilized sea urchin eggs.
The Journal of biological chemistry 1984;259(10):6516-25.
1984: J Richard McIntosh; U Euteneuer
Tubulin hooks as probes for microtubule polarity: an analysis of the method and an evaluation of data on microtubule polarity in the mitotic spindle.
The Journal of cell biology 1984;98(2):525-33.
1983: M Zavortink; Michael J Welsh; J Richard McIntosh
The distribution of calmodulin in living mitotic cells.
Experimental cell research 1983;149(2):375-85.
1983: J G Izant; J A Weatherbee; J Richard McIntosh
A microtubule-associated protein antigen unique to mitotic spindle microtubules in PtK1 cells.
The Journal of cell biology 1983;96(2):424-34.
1982: J M Mullins; J Richard McIntosh
Isolation and initial characterization of the mammalian midbody.
The Journal of cell biology 1982;94(3):654-61.
1982: U Euteneuer; W T Jackson; J Richard McIntosh
Polarity of spindle microtubules in Haemanthus endosperm.
The Journal of cell biology 1982;94(3):644-53.
1982: J G Izant; J A Weatherbee; J Richard McIntosh
A microtubule-associated protein in the mitotic spindle and the interphase nucleus.
Nature 1982;295(5846):248-50.
1982: J Richard McIntosh
Microscopic methods for analysis of mitotic spindle structure.
Methods in cell biology 1982;25 Pt B():33-56.
1981: U Euteneuer; J Richard McIntosh
Structural polarity of kinetochore microtubules in PtK1 cells.
The Journal of cell biology 1981;89(2):338-45.
1981: U Euteneuer; J Richard McIntosh
Polarity of some motility-related microtubules.
Proceedings of the National Academy of Sciences of the United States of America 1981;78(1):372-6.
1980: U Euteneuer; J Richard McIntosh
Polarity of midbody and phragmoplast microtubules.
The Journal of cell biology 1980;87(2 Pt 1):509-15.
1980: S R Heidemann; G W Zieve; J Richard McIntosh
Evidence for microtubule subunit addition to the distal end of mitotic structures in vitro.
The Journal of cell biology 1980;87(1):152-9.
1980: G W Zieve; S R Heidemann; J Richard McIntosh
Isolation and partial characterization of a cage of filaments that surrounds the mammalian mitotic spindle.
The Journal of cell biology 1980;87(1):160-9.
1980: J G Izant; J Richard McIntosh
Microtubule-associated proteins: a monoclonal antibody to MAP2 binds to differentiated neurons.
Proceedings of the National Academy of Sciences of the United States of America 1980;77(8):4741-5.
1980: S R Heidemann; J Richard McIntosh
Visualization of the structural polarity of microtubules.
Nature 1980;286(5772):517-9.
1980: Danny L Brower; J Richard McIntosh
The effects of applied electric fields on Micrasterias. I. Morphogenesis and the pattern of cell wall deposition.
Journal of cell science 1980;42():261-77.
1980: G W Zieve; D Turnbull; J M Mullins; J Richard McIntosh
Production of large numbers of mitotic mammalian cells by use of the reversible microtubule inhibitor nocodazole. Nocodazole accumulated mitotic cells.
Experimental cell research 1980;126(2):397-405.
1979: K L McDonald; M K Edwards; J Richard McIntosh
Cross-sectional structure of the central mitotic spindle of Diatoma vulgare. Evidence for specific interactions between antiparallel microtubules.
The Journal of cell biology 1979;83(2 Pt 1):443-61.
1979: J Richard McIntosh; K L McDonald; M K Edwards; B M Ross
Three-dimensional structure of the central mitotic spindle of Diatoma vulgare.
The Journal of cell biology 1979;83(2 Pt 1):428-42.
1979: J M Mullins; J Richard McIntosh
Birefringence of the mammalian midbody.
Experimental cell research 1979;121(2):395-9.
1979: J Richard McIntosh; J E Sisken; L K Chu
Structural studies on mitotic spindles isolated from cultured human cells.
Journal of ultrastructure research 1979;66(1):40-52.
1977: K McDonald; J D Pickett-Heaps; J Richard McIntosh; D H Tippit
On the mechanism of anaphase spindle elongation in Diatoma vulgare.
The Journal of cell biology 1977;74(2):377-88.
1977: W Z Cande; E Lazarides; J Richard McIntosh
A comparison of the distribution of actin and tubulin in the mammalian mitotic spindle as seen by indirect immunofluorescence.
The Journal of cell biology 1977;72(3):552-67.
1977: J L Turner; J Richard McIntosh
Isolation of the mitotic apparatus.
Methods in cell biology 1977;16():373-9.
1976: J A Snyder; J Richard McIntosh
Biochemistry and physiology of microtubules.
Annual review of biochemistry 1976;45():699-720.
1975: J A Snyder; J Richard McIntosh
Initiation and growth of microtubules from mitotic centers in lysed mammalian cells.
The Journal of cell biology 1975;67(3):744-60.
1975: J Richard McIntosh; W Z Cande; J A Snyder
Structure and physiology of the mammalian mitotic spindle.
Society of General Physiologists series 1975;30():31-76.
1974: W Z Cande; J Snyder; D Smith; K Summers; J Richard McIntosh
A functional mitotic spindle prepared from mammalian cells in culture.
Proceedings of the National Academy of Sciences of the United States of America 1974;71(4):1559-63.
1974: J Richard McIntosh
Bridges between microtubules.
The Journal of cell biology 1974;61(1):166-87.
1974: J Richard McIntosh
An introduction to microtubules.
Journal of supramolecular structure 1974;2(2-4):385-92.
1973: D S Oppenheim; B T Hauschaka; J Richard McIntosh
Anaphase motions in dilute colchicine. Evidence of two phases in chromosome segregation.
Experimental cell research 1973;79(1):95-105.
1973: D S Oppenheim; B T Hauschka; J Richard McIntosh
Anaphase motions in dilute colchicine. Evidence of two phases in chromosome segregation.
Experimental eye research 1973;79(1):95-105.
1973: J Richard McIntosh; E S Ogata; Story C Landis
The axostyle of Saccinobaculus. I. Structure of the organism and its microtubule bundle.
The Journal of cell biology 1973;56(2):304-23.
1973: J Richard McIntosh
The axostyle of Saccinobaculus. II. Motion of the microtubule bundle and a structural comparison of straight and bent axostyles.
The Journal of cell biology 1973;56(2):324-39.
1972: Timothy P. Fitzharris; R A Bloodgood; J Richard McIntosh
The effect of fixation on the wave propagation of the protozoan axostyle.
Tissue & cell 1972;4(2):219-25.
1970: P K Hepler; J Richard McIntosh; S Cleland
Intermicrotubule bridges in mitotic spindle apparatus.
The Journal of cell biology 1970;45(2):438-44.
1968: STEVEN ROSENBERG; J Richard McIntosh
Erythrocyte membranes: effects on sonication.
Biochimica et biophysica acta 1968;163(3):285-9.
1967: J Richard McIntosh; K R Porter
Microtubules in the spermatids of the domestic fowl.
The Journal of cell biology 1967;35(1):153-73.