FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Robert McKenna

Research Profile

Procedures

X Ray Crystallography

Concepts & Ideas

Chemicals & Drugs

Anatomy

Capsid

Phenomena

Genes & Molecular Sequences

Amino Acid Sequences

Living Beings

Physiology

Amino Acid Substitution

Co-author Network

Publications

TOP 3
Mayank Aggarwal; Christopher D Boone; Bhargav Kondeti; David N Silverman; Chingkuang Tu; Robert McKenna
Effects of cryoprotectants on the structure and thermostability of the human carbonic anhydrase II-acetazolamide complex.
Sujata Halder; Robert McKenna; Hyun-Joo Nam; Nathalie Salomé; Michèle Vogel; Christiane Dinsart; Lakshmanan Govindasamy; Mavis Agbandje-McKenna
Structural characterization of H-1 parvovirus: comparison of infectious virions to empty capsids.
Balasubramanian Venkatakrishnan; Joseph Yarbrough; Antonette Bennett; Brian Bothner; John Domsic; Olga G Kozyreva; Robert McKenna; Nicholas Muzyczka; R Jude Samulski; Mavis Agbandje-McKenna
Structure and dynamics of adeno-associated virus serotype 1 VP1-unique N-terminal domain and its role in capsid trafficking.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Robert McKenna (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Mayank Aggarwal; Christopher D Boone; Bhargav Kondeti; David N Silverman; Chingkuang Tu; Robert McKenna
Effects of cryoprotectants on the structure and thermostability of the human carbonic anhydrase II-acetazolamide complex.
Acta crystallographica. Section D, Biological crystallography 2013;69(Pt 5):860-5.
2013: Sujata Halder; Robert McKenna; Hyun-Joo Nam; Nathalie Salomé; Michèle Vogel; Christiane Dinsart; Lakshmanan Govindasamy; Mavis Agbandje-McKenna
Structural characterization of H-1 parvovirus: comparison of infectious virions to empty capsids.
Journal of virology 2013;87(9):5128-40.
2013: Balasubramanian Venkatakrishnan; Joseph Yarbrough; Antonette Bennett; Brian Bothner; John Domsic; Olga G Kozyreva; Robert McKenna; Nicholas Muzyczka; R Jude Samulski; Mavis Agbandje-McKenna
Structure and dynamics of adeno-associated virus serotype 1 VP1-unique N-terminal domain and its role in capsid trafficking.
Journal of virology 2013;87(9):4974-84.
2013: Shyamasri Biswas; Fabrizio Carta; Robert McKenna; Andrea Scozzafava; Claudiu T Supuran
Structural effect of phenyl ring compared to thiadiazole based adamantyl-sulfonamides on carbonic anhydrase inhibition.
Bioorganic & medicinal chemistry 2013;21(8):2314-8.
2013: Mayank Aggarwal; Christopher D Boone; Bhargav Kondeti; Robert McKenna
Structural annotation of human carbonic anhydrases.
Journal of enzyme inhibition and medicinal chemistry 2013;28(2):267-77.
2013: Mayank Aggarwal; Bhargav Kondeti; Robert McKenna
Insights towards sulfonamide drug specificity in α-carbonic anhydrases.
Bioorganic & medicinal chemistry 2013;21(6):1526-33.
2013: Rose Mikulski; Mayank Aggarwal; Balendu Sankara Avvaru; Robert McKenna; Katherine H Sippel; Chingkuang Tu; Dayne West; David N Silverman
Water networks in fast proton transfer during catalysis by human carbonic anhydrase II.
Biochemistry 2013;52(1):125-31.
2013: Mayank Aggarwal; Bhargav Kondeti; Robert McKenna
Anticonvulsant/antiepileptic carbonic anhydrase inhibitors: a patent review.
Expert opinion on therapeutic patents 2013;23(6):717-24.
2013: Sabrina Zimmerman; John F Domsic; Robert McKenna; Arthur H Robbins; David N Silverman; Chingkuang Tu; James G Ferry
Role of Trp19 and Tyr200 in catalysis by the γ-class carbonic anhydrase from Methanosarcina thermophila.
Archives of biochemistry and biophysics 2013;529(1):11-7.
2012: Sujata Halder; Robert McKenna; Hyun-Joo Nam; Nathalie Salomé; Michèle Vogel; Christiane Dinsart; Lakshmanan Govindasamy; Mavis Agbandje-McKenna
Production, purification, crystallization and structure determination of H-1 Parvovirus.
Acta crystallographica. Section F, Structural biology and crystallization communications 2012;68(Pt 12):1571-6.
2012: Dayne West; Sol M Gruner; Chae Un Kim; Arthur H Robbins; David N Silverman; Chingkuang Tu; Robert McKenna
Structural and kinetic effects on changes in the CO(2) binding pocket of human carbonic anhydrase II.
Biochemistry 2012;51(45):9156-63.
2012: S Zoë Fisher; Andrey Y Kovalevsky; Mayank Aggarwal; David N Silverman; Robert McKenna
Neutron diffraction of acetazolamide-bound human carbonic anhydrase II reveals atomic details of drug binding.
Journal of the American Chemical Society 2012;134(36):14726-9.
2012: Natalia Díaz Torres; Guillermo González; Shyamasri Biswas; Kathleen M Scott; Robert McKenna
Preliminary X-ray crystallographic analysis of α-carbonic anhydrase from Thiomicrospira crunogena XCL-2.
Acta crystallographica. Section F, Structural biology and crystallization communications 2012;68(Pt 9):1064-6.
2012: Mayank Aggarwal; Robert McKenna
Update on carbonic anhydrase inhibitors: a patent review (2008 - 2011).
Expert opinion on therapeutic patents 2012;22(8):903-15.
2012: Brittney L Gurda; Jürgen A Kleinschmidt; Robert McKenna; Matthias Naumer; Robert Ng; Norman H Olson; Ruth Popa-Wagner; Christina Raupp; Timothy S Baker; Mavis Agbandje-McKenna
Mapping a neutralizing epitope onto the capsid of adeno-associated virus serotype 8.
Journal of virology 2012;86(15):7739-51.
2012: Zoë Fisher; David Silverman; Chingkuang Tu; Balasubramanian Venkatakrishnan; Mavis Agbandje-McKenna; Mayank Aggarwal; Shya Masri Biswas; Christopher D Boone; Robert McKenna
Kinetic and structural characterization of thermostabilized mutants of human carbonic anhydrase II.
Protein engineering, design & selection : PEDS 2012;25(7):347-55.
2012: Michael A DiMattia; Brittney L Gurda; Robert McKenna; Matthew Mitchell; Nicholas Muzyczka; Hyun-Joo Nam; Norman H Olson; Mark Potter; Robert S Sinkovits; Kim Van Vliet; Sergei Zolotukhin; George Aslanidi; Timothy S Baker; Antonette Bennett; Barry J Byrne; Mavis Agbandje-McKenna
Structural insight into the unique properties of adeno-associated virus serotype 9.
Journal of virology 2012;86(12):6947-58.
2012: Chingkuang Tu; Andrea Alvarado; Lauren Foster; Robert McKenna; David N Silverman; Susan C Frost
Role of zinc in catalytic activity of carbonic anhydrase IX.
Archives of biochemistry and biophysics 2012;521(1-2):90-4.
2012: Balasubramanian Venkatakrishnan; Miorel-Lucian Palii; Mavis Agbandje-McKenna; Robert McKenna
Mining the protein data bank to differentiate error from structural variation in clustered static structures: an examination of HIV protease.
Viruses 2012;4(3):348-62.
2011: Rose Mikulski; Arthur H Robbins; David N Silverman; Chingkuang Tu; John F Domsic; George Ling; Robert McKenna
Structure and catalysis by carbonic anhydrase II: role of active-site tryptophan 5.
Archives of biochemistry and biophysics 2011;516(2):97-102.
2011: Christopher O Paschall; Arthur H Robbins; Jennifer A Thompson; Ankita Chiraniya; Jaclyn N Hayner; Melissa R Marzahn; Robert McKenna; Mike O'Donnell; Linda B Bloom
The Escherichia coli clamp loader can actively pry open the β-sliding clamp.
The Journal of biological chemistry 2011;286(49):42704-14.
2011: Zoë Fisher; Andrey Y Kovalevsky; Robert McKenna; Marat Mustyakimov; David N Silverman; Paul Langan
Neutron structure of human carbonic anhydrase II: a hydrogen-bonded water network "switch" is observed between pH 7.8 and 10.0.
Biochemistry 2011;50(44):9421-3.
2011: Hyun-Joo Nam; Mark Potter; Maxim Salganik; Barry Byrne; Brittney L Gurda; Robert McKenna; Nicholas Muzyczka; Mavis Agbandje-McKenna
Structural studies of adeno-associated virus serotype 8 capsid transitions associated with endosomal trafficking.
Journal of virology 2011;85(22):11791-9.
2011: S H Subramony; Tetsuo Ashizawa; Balu Avvaru; Leigh Langford; Robert McKenna; Teepu Siddique; V Venkataraman Vedanarayanan
Confirmation of the severe phenotypic effect of serine at codon 41 of the superoxide dismutase 1 gene.
Muscle & nerve 2011;44(4):499-502.
2011: Shyamasri Biswas; Robert McKenna; Andrea Scozzafava; Mayank Aggarwal; Özlen Güzel; Claudiu T Supuran
Conformational variability of different sulfonamide inhibitors with thienyl-acetamido moieties attributes to differential binding in the active site of cytosolic human carbonic anhydrase isoforms.
Bioorganic & medicinal chemistry 2011;19(12):3732-8.
2011: C Mark Maupin; Norberto Castillo; Srabani Taraphder; Chingkuang Tu; Robert McKenna; David N Silverman; Gregory A Voth
Chemical rescue of enzymes: proton transfer in mutants of human carbonic anhydrase II.
Journal of the American Chemical Society 2011;133(16):6223-34.
2011: Rose Mikulski; Balendu Sankara Avvaru; Chingkuang Tu; Nicolette Case; Robert McKenna; David N Silverman
Kinetic and crystallographic studies of the role of tyrosine 7 in the active site of human carbonic anhydrase II.
Archives of biochemistry and biophysics 2011;506(2):181-7.
2011: Katherine H Sippel; Balasubramanian Venkatakrishnan; Susan K Boehlein; Banumathi Sankaran; Jeanne G Quirit; Lakshmanan Govindasamy; Mavis Agbandje-McKenna; Steve Goodison; Charles J Rosser; Robert McKenna
Insights into Mycoplasma genitalium metabolism revealed by the structure of MG289, an extracytoplasmic thiamine binding lipoprotein.
Proteins 2011;79(2):528-36.
2010: Robert Ng; Lakshmanan Govindasamy; Brittney L Gurda; Robert McKenna; Olga G Kozyreva; R Jude Samulski; Kristin N Parent; Timothy S Baker; Mavis Agbandje-McKenna
Structural characterization of the dual glycan binding adeno-associated virus serotype 6.
Journal of virology 2010;84(24):12945-57.
2010: Fabio Pacchiano; Mayank Aggarwal; Balendu Sankara Avvaru; Arthur H Robbins; Andrea Scozzafava; Robert McKenna; Claudiu T Supuran
Selective hydrophobic pocket binding observed within the carbonic anhydrase II active site accommodate different 4-substituted-ureido-benzenesulfonamides and correlate to inhibitor potency.
Chemical communications (Cambridge, England) 2010;46(44):8371-3.
2010: S Zoë Fisher; A Y Kovalevsky; J Domsic; M Mustyakimov; David N Silverman; Robert McKenna; Paul Langan
Enzymes for carbon sequestration: neutron crystallographic studies of carbonic anhydrase.
Acta crystallographica. Section D, Biological crystallography 2010;66(Pt 11):1178-83.
2010: Balendu Sankara Avvaru; Daniel J Arenas; Chingkuang Tu; D B Tanner; Robert McKenna; David N Silverman
Comparison of solution and crystal properties of Co(II)-substituted human carbonic anhydrase II.
Archives of biochemistry and biophysics 2010;502(1):53-9.
2010: John F Domsic; Wilton Williams; S Zoë Fisher; Chingkuang Tu; Mavis Agbandje-McKenna; David N Silverman; Robert McKenna
Structural and kinetic study of the extended active site for proton transfer in human carbonic anhydrase II.
Biochemistry 2010;49(30):6394-9.
2010: Arthur H Robbins; John F Domsic; Mavis Agbandje-McKenna; Robert McKenna
Emerging from pseudo-symmetry: the redetermination of human carbonic anhydrase II in monoclinic P2(1) with a doubled a axis.
Acta crystallographica. Section D, Biological crystallography 2010;66(Pt 8):950-2.
2010: Balendu Sankara Avvaru; Jason M Wagner; Alfonso Maresca; Andrea Scozzafava; Arthur H Robbins; Claudiu T Supuran; Robert McKenna
Carbonic anhydrase inhibitors. The X-ray crystal structure of human isoform II in adduct with an adamantyl analogue of acetazolamide resides in a less utilized binding pocket than most hydrophobic inhibitors.
Bioorganic & medicinal chemistry letters 2010;20(15):4376-81.
2010: Jason Wagner; Balendu Sankara Avvaru; Arthur H Robbins; Andrea Scozzafava; Claudiu T Supuran; Robert McKenna
Coumarinyl-substituted sulfonamides strongly inhibit several human carbonic anhydrase isoforms: solution and crystallographic investigations.
Bioorganic & medicinal chemistry 2010;18(14):4873-8.
2010: Brittney L Gurda; Kristin N Parent; Heather Bladek; Robert S Sinkovits; Michael A DiMattia; Chelsea Rence; Alejandro Castro; Robert McKenna; Norm Olson; Kevin Brown; Timothy S Baker; Mavis Agbandje-McKenna
Human bocavirus capsid structure: insights into the structural repertoire of the parvoviridae.
Journal of virology 2010;84(12):5880-9.
2010: Arthur H Robbins; John F Domsic; Mavis Agbandje-McKenna; Robert McKenna
Structure of a monoclinic polymorph of human carbonic anhydrase II with a doubled a axis.
Acta crystallographica. Section D, Biological crystallography 2010;66(Pt 5):628-34.
2010: Arthur H Robbins; Roxana M Coman; Edith Bracho-Sanchez; Marty A Fernandez; C Taylor Gilliland; Mi Li; Mavis Agbandje-McKenna; Alexander Wlodawer; Ben M Dunn; Robert McKenna
Structure of the unbound form of HIV-1 subtype A protease: comparison with unbound forms of proteases from other HIV subtypes.
Acta crystallographica. Section D, Biological crystallography 2010;66(Pt 3):233-42.
2010: John F Domsic; Robert McKenna
Sequestration of carbon dioxide by the hydrophobic pocket of the carbonic anhydrases.
Biochimica et biophysica acta 2010;1804(2):326-31.
2010: S Zoë Fisher; Andrey Y Kovalevsky; John F Domsic; Marat Mustyakimov; Robert McKenna; David N Silverman; Paul A Langan
Neutron structure of human carbonic anhydrase II: implications for proton transfer.
Biochemistry 2010;49(3):415-21.
2010: Balendu Sankara Avvaru; Chae Un Kim; Katherine H Sippel; Sol M Gruner; Mavis Agbandje-McKenna; David N Silverman; Robert McKenna
A short, strong hydrogen bond in the active site of human carbonic anhydrase II.
Biochemistry 2010;49(2):249-51.
2009: Katherine H Sippel; Arthur H Robbins; John Domsic; Caroli Genis; Mavis Agbandje-McKenna; Robert McKenna
High-resolution structure of human carbonic anhydrase II complexed with acetazolamide reveals insights into inhibitor drug design.
Acta crystallographica. Section F, Structural biology and crystallization communications 2009;65(Pt 10):992-5.
2009: Katherine H Sippel; Susan K Boehlein; Yoshihisa Sakai; Jeanne G Quirit; Mavis Agbandje-McKenna; Charles J Rosser; Robert McKenna
Cloning, expression, purification, crystallization and preliminary X-ray analysis of Mycoplasma genitalium protein MG289.
Acta crystallographica. Section F, Structural biology and crystallization communications 2009;65(Pt 9):910-2.
2009: C Mark Maupin; Jiayin Zheng; Chingkuang Tu; Robert McKenna; David N Silverman; Gregory A Voth
Effect of active-site mutation at Asn67 on the proton transfer mechanism of human carbonic anhydrase II.
Biochemistry 2009;48(33):7996-8005.
2009: Balendu Sankara Avvaru; Scott A Busby; Michael J Chalmers; Patrick R Griffin; Balasubramanian Venkatakrishnan; Mavis Agbandje-McKenna; David N Silverman; Robert McKenna
Apo-human carbonic anhydrase II revisited: implications of the loss of a metal in protein structure, stability, and solvent network.
Biochemistry 2009;48(31):7365-72.
2009: Matthew Mitchell; Hyun-Joo Nam; Adam Carter; Angela McCall; Chelsea Rence; Antonette Bennett; Brittney Gurda; Robert McKenna; Mark Porter; Yoshihisa Sakai; Barry J Byrne; Nicholas Muzyczka; George Aslanidi; Sergei Zolotukhin; Mavis Agbandje-McKenna
Production, purification and preliminary X-ray crystallographic studies of adeno-associated virus serotype 9.
Acta crystallographica. Section F, Structural biology and crystallization communications 2009;65(Pt 7):715-8.
2009: C Mark Maupin; Robert McKenna; David N Silverman; Gregory A Voth
Elucidation of the proton transport mechanism in human carbonic anhydrase II.
Journal of the American Chemical Society 2009;131(22):7598-608.
2009: Peng Liu; Melissa R Marzahn; Arthur H Robbins; Hugo Gutierrez de teran; David Rodríguez; Scott H McClung; Stanley M Stevens; Charles A Yowell; John B Dame; Robert McKenna; Ben M Dunn
Recombinant plasmepsin 1 from the human malaria parasite plasmodium falciparum: enzymatic characterization, active site inhibitor design, and structural analysis.
Biochemistry 2009;48(19):4086-99.
2009: Katherine H Sippel; Arthur H Robbins; Robbie Reutzel; Susan K Boehlein; Kazunori Namiki; Steve Goodison; Mavis Agbandje-McKenna; Charles J Rosser; Robert McKenna
Structural insights into the extracytoplasmic thiamine-binding lipoprotein p37 of Mycoplasma hyorhinis.
Journal of bacteriology 2009;191(8):2585-92.
2009: Arthur H Robbins; Ben M Dunn; Mavis Agbandje-McKenna; Robert McKenna
Crystallographic evidence for noncoplanar catalytic aspartic acids in plasmepsin II resides in the Protein Data Bank.
Acta crystallographica. Section D, Biological crystallography 2009;65(Pt 3):294-6.
2009: Hazel C Levy; valorie bowman; Lakshmanan Govindasamy; Robert McKenna; Kevin Nash; Kenneth H Warrington; Weijun Chen; Nicholas Muzyczka; Xiaodong Yan; Timothy S Baker; Mavis Agbandje-McKenna
Heparin binding induces conformational changes in Adeno-associated virus serotype 2.
Journal of structural biology 2009;165(3):146-56.
2009: Caroli Genis; Katherine H Sippel; Nicolette Case; Wengang Cao; Balendu Sankara Avvaru; Lawrence J Tartaglia; Lakshmanan Govindasamy; Chingkuang Tu; Mavis Agbandje-McKenna; David N Silverman; Charles J Rosser; Robert McKenna
Design of a carbonic anhydrase IX active-site mimic to screen inhibitors for possible anticancer properties.
Biochemistry 2009;48(6):1322-31.
2008: John F Domsic; Balendu Sankara Avvaru; Chae Un Kim; Sol M Gruner; Mavis Agbandje-McKenna; David N Silverman; Robert McKenna
Entrapment of carbon dioxide in the active site of carbonic anhydrase II.
The Journal of biological chemistry 2008;283(45):30766-71.
2008: Katherine H Sippel; Arthur H Robbins; Robbie Reutzel; John Domsic; Susan K Boehlein; Lakshmanan Govindasamy; Mavis Agbandje-McKenna; Charles J Rosser; Robert McKenna
Structure determination of the cancer-associated Mycoplasma hyorhinis protein Mh-p37.
Acta crystallographica. Section D, Biological crystallography 2008;64(Pt 11):1172-8.
2008: C Mark Maupin; Marissa G Saunders; Ian F Thorpe; Robert McKenna; David N Silverman; Gregory A Voth
Origins of enhanced proton transport in the Y7F mutant of human carbonic anhydrase II.
Journal of the American Chemical Society 2008;130(34):11399-408.
2008: Roxana M Coman; Arthur H Robbins; Maureen M Goodenow; Ben M Dunn; Robert McKenna
High-resolution structure of unbound human immunodeficiency virus 1 subtype C protease: implications of flap dynamics and drug resistance.
Acta crystallographica. Section D, Biological crystallography 2008;D64(Pt 7):754-63.
2008: Patrick Quint; John F Domsic; Diane E Cabelli; Robert McKenna; David N Silverman
Role of a glutamate bridge spanning the dimeric interface of human manganese superoxide dismutase.
Biochemistry 2008;47(16):4621-8.
2008: José C Clemente; Arthur Robbins; Paula Graña; M Rita Paleo; Juan F Correa; M Carmen Villaverde; F Javier Sardina; Lakshmanan Govindasamy; Mavis Agbandje-McKenna; Robert McKenna; Ben M Dunn; Fredy Sussman
Design, synthesis, evaluation, and crystallographic-based structural studies of HIV-1 protease inhibitors with reduced response to the V82A mutation.
Journal of medicinal chemistry 2008;51(4):852-60.
2008: Roxana M Coman; Arthur H Robbins; Marty A Fernandez; C Taylor Gilliland; Anthony A Sochet; Maureen M Goodenow; Robert McKenna; Ben M Dunn
The contribution of naturally occurring polymorphisms in altering the biochemical and structural characteristics of HIV-1 subtype C protease.
Biochemistry 2008;47(2):731-43.
2007: Odayme Quesada; Brittney Gurda; Lakshmanan Govindasamy; Robert McKenna; Erik Kohlbrenner; George Aslanidi; Sergei Zolotukhin; Nicholas Muzyczka; Mavis Agbandje-McKenna
Production, purification and preliminary X-ray crystallographic studies of adeno-associated virus serotype 7.
Acta crystallographica. Section F, Structural biology and crystallization communications 2007;63(Pt 12):1073-6.
2007: Hyun-Joo Nam; Michael Douglas Lane; Eric Padron; Brittney Gurda; Robert McKenna; Erik Kohlbrenner; George Aslanidi; Barry Byrne; Nicholas Muzyczka; Sergei Zolotukhin; Mavis Agbandje-McKenna
Structure of adeno-associated virus serotype 8, a gene therapy vector.
Journal of virology 2007;81(22):12260-71.
2007: Tara Sabo- Attwood; Jason L Blum; Kevin J Kroll; Vishal Patel; Detlef Birkholz; Nancy J Szabo; S Zoë Fisher; Robert McKenna; Martha Campbell-Thompson; Nancy D Denslow
Distinct expression and activity profiles of largemouth bass (Micropterus salmoides) estrogen receptors in response to estradiol and nonylphenol.
Journal of molecular endocrinology 2007;39(4):223-37.
2007: David N Silverman; Robert McKenna
Solvent-mediated proton transfer in catalysis by carbonic anhydrase.
Accounts of chemical research 2007;40(8):669-75.
2007: Ileana Elder; Zoë Fisher; Philip J Laipis; Chingkuang Tu; Robert McKenna; David N Silverman
Structural and kinetic analysis of proton shuttle residues in the active site of human carbonic anhydrase III.
Proteins 2007;68(1):337-43.
2007: Roxana M Coman; Arthur Robbins; Maureen M Goodenow; Robert McKenna; Ben M Dunn
Expression, purification and preliminary X-ray crystallographic studies of the human immunodeficiency virus 1 subtype C protease.
Acta crystallographica. Section F, Structural biology and crystallization communications 2007;63(Pt 4):320-3.
2007: S Zoë Fisher; Chingkuang Tu; Deepa Bhatt; Lakshmanan Govindasamy; Mavis Agbandje-McKenna; Robert McKenna; David N Silverman
Speeding up proton transfer in a fast enzyme: kinetic and crystallographic studies on the effect of hydrophobic amino acid substitutions in the active site of human carbonic anhydrase II.
Biochemistry 2007;46(12):3803-13.
2007: S Zoë Fisher; C Mark Maupin; Monika Budayova-Spano; Lakshmanan Govindasamy; Chingkuang Tu; Mavis Agbandje-McKenna; David N Silverman; Gregory A Voth; Robert McKenna
Atomic crystal and molecular dynamics simulation structures of human carbonic anhydrase II: insights into the proton transfer mechanism.
Biochemistry 2007;46(11):2930-7.
2007: Deepa Bhatt; S Zoë Fisher; Chingkuang Tu; Robert McKenna; David N Silverman
Location of binding sites in small molecule rescue of human carbonic anhydrase II.
Biophysical journal 2007;92(2):562-70.
2006: Edward B Miller; Brittney Gurda-Whitaker; Lakshmanan Govindasamy; Robert McKenna; Sergei Zolotukhin; Nicholas Muzyczka; Mavis Agbandje-McKenna
Production, purification and preliminary X-ray crystallographic studies of adeno-associated virus serotype 1.
Acta crystallographica. Section F, Structural biology and crystallization communications 2006;62(Pt 12):1271-4.
2006: Lakshmanan Govindasamy; Eric Padron; Robert McKenna; Nicholas Muzyczka; Nikola Kaludov; John A Chiorini; Mavis Agbandje-McKenna
Structurally mapping the diverse phenotype of adeno-associated virus serotype 4.
Journal of virology 2006;80(23):11556-70.
2006: Hyun-Joo Nam; Brittney Gurda-Whitaker; Wand Yee Gan; Shawen Ilaria; Robert McKenna; Padmaja Mehta; Richard A Alvarez; Mavis Agbandje-McKenna
Identification of the sialic acid structures recognized by minute virus of mice and the role of binding affinity in virulence adaptation.
The Journal of biological chemistry 2006;281(35):25670-7.
2006: S Zoë Fisher; Iyerus Tariku; Nicolette M Case; Chingkuang Tu; Theresa J Seron; David N Silverman; Paul J Linser; Robert McKenna
Expression, purification, kinetic, and structural characterization of an alpha-class carbonic anhydrase from Aedes aegypti (AaCA1).
Biochimica et biophysica acta 2006;1764(8):1413-9.
2006: S Zoë Fisher; Lakshmanan Govindasamy; Nicholas Boyle; Mavis Agbandje-McKenna; David N Silverman; G Michael Blackburn; Robert McKenna
X-ray crystallographic studies reveal that the incorporation of spacer groups in carbonic anhydrase inhibitors causes alternate binding modes.
Acta crystallographica. Section F, Structural biology and crystallization communications 2006;62(Pt 7):618-22.
2006: José C Clemente; Roxana M Coman; Michele M Thiaville; Linda K Janka; Jennifer A Jeung; Sarawut Nukoolkarn; Lakshmanan Govindasamy; Mavis Agbandje-McKenna; Robert McKenna; Wichet Leelamanit; Maureen M Goodenow; Ben M Dunn
Analysis of HIV-1 CRF_01 A/E protease inhibitor resistance: structural determinants for maintaining sensitivity and developing resistance to atazanavir.
Biochemistry 2006;45(17):5468-77.
2006: José C Clemente; Lakshmanan Govindasamy; Amrita Madabushi; S Zoë Fisher; Rebecca E Moose; Charles A Yowell; Koushi Hidaka; Tooru Kimura; Yoshio Hayashi; Yoshiaki Kiso; Mavis Agbandje-McKenna; John B Dame; Ben M Dunn; Robert McKenna
Structure of the aspartic protease plasmepsin 4 from the malarial parasite Plasmodium malariae bound to an allophenylnorstatine-based inhibitor.
Acta crystallographica. Section D, Biological crystallography 2006;62(Pt 3):246-52.
2006: S Zoë Fisher; Lakshmanan Govindasamy; Chingkuang Tu; Mavis Agbandje-McKenna; David N Silverman; Hannu J Rajaniemi; Robert McKenna
Structure of human salivary alpha-amylase crystallized in a C-centered monoclinic space group.
Acta crystallographica. Section F, Structural biology and crystallization communications 2006;62(Pt 2):88-93.
2006: Patrick Quint; Robbie Reutzel; Rose Mikulski; Robert McKenna; David N Silverman
Crystal structure of nitrated human manganese superoxide dismutase: mechanism of inactivation.
Free radical biology & medicine 2006;40(3):453-8.
2006: Alberto López-Bueno; Mari-Paz Rubio; Nathan Bryant; Robert McKenna; Mavis Agbandje-McKenna; José M Almendral
Host-selected amino acid changes at the sialic acid binding pocket of the parvovirus capsid modulate cell binding affinity and determine virulence.
Journal of virology 2006;80(3):1563-73.
2006: Monika Budayova-Spano; S Zoë Fisher; Marie Thérèse Dauvergne; Mavis Agbandje-McKenna; David N Silverman; Dean A A Myles; Robert McKenna
Production and X-ray crystallographic analysis of fully deuterated human carbonic anhydrase II.
Acta crystallographica. Section F, Structural biology and crystallization communications 2006;62(Pt 1):6-9.
2005: Deepa Bhatt; Chingkuang Tu; S Zoë Fisher; Jose A Hernandez Prada; Robert McKenna; David N Silverman
Proton transfer in a Thr200His mutant of human carbonic anhydrase II.
Proteins 2005;61(2):239-45.
2005: Michael DiMattia; Lakshmanan Govindasamy; Hazel C Levy; Brittney Gurda-Whitaker; Amy Kalina; Erik Kohlbrenner; John A Chiorini; Robert McKenna; Nicholas Muzyczka; Sergei Zolotukhin; Mavis Agbandje-McKenna
Production, purification, crystallization and preliminary X-ray structural studies of adeno-associated virus serotype 5.
Acta crystallographica. Section F, Structural biology and crystallization communications 2005;61(Pt 10):917-21.
2005: Maria Kontou; Lakshmanan Govindasamy; Hyun-Joo Nam; Nathan Bryant; Antonio Luis Llamas-Saiz; Concepción Foces-Foces; Eva Hernando; Mari-Paz Rubio; Robert McKenna; José M Almendral; Mavis Agbandje-McKenna
Structural determinants of tissue tropism and in vivo pathogenicity for the parvovirus minute virus of mice.
Journal of virology 2005;79(17):10931-43.
2005: David M Duda; Chingkuang Tu; S Zoë Fisher; Haiqian An; Craig Yoshioka; Lakshmanan Govindasamy; Philip J Laipis; Mavis Agbandje-McKenna; David N Silverman; Robert McKenna
Human carbonic anhydrase III: structural and kinetic study of catalysis and proton transfer.
Biochemistry 2005;44(30):10046-53.
2005: Catherine M Ketcham; Satoshi Anai; Robbie Reutzel; Shijie Sheng; Sheldon M Schuster; Ryan B Brenes; Mavis Agbandje-McKenna; Robert McKenna; Charles J Rosser; Susan K Boehlein
p37 Induces tumor invasiveness.
Molecular cancer therapeutics 2005;4(7):1031-8.
2005: Michael Douglas Lane; Hyun-Joo Nam; Eric Padron; Brittney Gurda-Whitaker; Erik Kohlbrenner; George Aslanidi; Barry Byrne; Robert McKenna; Nicholas Muzyczka; Sergei Zolotukhin; Mavis Agbandje-McKenna
Production, purification, crystallization and preliminary X-ray analysis of adeno-associated virus serotype 8.
Acta crystallographica. Section F, Structural biology and crystallization communications 2005;61(Pt 6):558-61.
2005: Ileana Elder; Chingkuang Tu; Li-June Ming; Robert McKenna; David N Silverman
Proton transfer from exogenous donors in catalysis by human carbonic anhydrase II.
Archives of biochemistry and biophysics 2005;437(1):106-14.
2005: Eric Padron; valorie bowman; Nikola Kaludov; Lakshmanan Govindasamy; Hazel Levy; Phillip Nick; Robert McKenna; Nicholas Muzyczka; John A Chiorini; Timothy S Baker; Mavis Agbandje-McKenna
Structure of adeno-associated virus type 4.
Journal of virology 2005;79(8):5047-58.
2005: Bret B Beyer; Jodie V Johnson; Alfred Y Chung; Tang Li; Amrita Madabushi; Mavis Agbandje-McKenna; Robert McKenna; John B Dame; Ben M Dunn
Active-site specificity of digestive aspartic peptidases from the four species of Plasmodium that infect humans using chromogenic combinatorial peptide libraries.
Biochemistry 2005;44(6):1768-79.
2005: Amrita Madabushi; Sibani Chakraborty; S Zoë Fisher; José C Clemente; Charles A Yowell; Mavis Agbandje-McKenna; John B Dame; Ben M Dunn; Robert McKenna
Crystallization and preliminary X-ray analysis of the aspartic protease plasmepsin 4 from the malarial parasite Plasmodium malariae.
Acta crystallographica. Section F, Structural biology and crystallization communications 2005;61(Pt 2):228-31.
2005: Zoë Fisher; Jose A Hernandez Prada; Chingkuang Tu; David M Duda; Craig Yoshioka; Haiqian An; Lakshmanan Govindasamy; David N Silverman; Robert McKenna
Structural and kinetic characterization of active-site histidine as a proton shuttle in catalysis by human carbonic anhydrase II.
Biochemistry 2005;44(4):1097-105.
2004: Lakshmanan Govindasamy; Brenda Pedersen; Wei Lian; Thomas Kukar; Yunrong Gu; Shouguang Jin; Mavis Agbandje-McKenna; Donghai Wu; Robert McKenna
Structural insights and functional implications of choline acetyltransferase.
Journal of structural biology 2004;148(2):226-35.
2004: José C Clemente; Rebecca E Moose; Reena Hemrajani; Lisa R S Whitford; Lakshmanan Govindasamy; Robbie Reutzel; Robert McKenna; Mavis Agbandje-McKenna; Maureen M Goodenow; Ben M Dunn
Comparing the accumulation of active- and nonactive-site mutations in the HIV-1 protease.
Biochemistry 2004;43(38):12141-51.
2004: Lakshmanan Govindasamy; Robbie Reutzel; Mavis Agbandje-McKenna; Robert McKenna
Structural determination of a partially hemihedrally twinned actin crystal.
Acta crystallographica. Section D, Biological crystallography 2004;60(Pt 6):1040-7.
2004: Lakshmanan Govindasamy; Thomas Kukar; Wei Lian; Brenda Pedersen; Yunrong Gu; Mavis Agbandje-McKenna; Shouguang Jin; Robert McKenna; Donghai Wu
Structural and mutational characterization of L-carnitine binding to human carnitine acetyltransferase.
Journal of structural biology 2004;146(3):416-24.
2004: Robbie Reutzel; Craig Yoshioka; Lakshmanan Govindasamy; Elena G Yarmola; Mavis Agbandje-McKenna; michael bubb; Robert McKenna
Actin crystal dynamics: structural implications for F-actin nucleation, polymerization, and branching mediated by the anti-parallel dimer.
Journal of structural biology 2004;146(3):291-301.
2004: Carolina G Casado; G Javier Ortiz; Eric Padron; Samantha J Bean; Robert McKenna; Mavis Agbandje-McKenna; Margaret I Boulton
Isolation and characterization of subgenomic DNAs encapsidated in "single" T = 1 isometric particles of Maize streak virus.
Virology 2004;323(1):164-71.
2004: Wei Lian; Yunrong Gu; Brenda Pedersen; Thomas Kukar; Lakshmanan Govindasamy; Mavis Agbandje-McKenna; Shouguang Jin; Robert McKenna; Donghai Wu
Crystallization and preliminary X-ray crystallographic studies on recombinant rat choline acetyltransferase.
Acta crystallographica. Section D, Biological crystallography 2004;60(Pt 2):374-5.
2003: Michelle L Gumz; David M Duda; Robert McKenna; Charles S Wingo; Brian D Cain
Molecular modeling of the rabbit colonic (HKalpha2a) H+, K+ ATPase.
Journal of molecular modeling 2003;9(5):283-9.
2003: Donghai Wu; Lakshmanan Govindasamy; Wei Lian; Yunrong Gu; Thomas Kukar; Mavis Agbandje-McKenna; Robert McKenna
Structure of human carnitine acetyltransferase. Molecular basis for fatty acyl transfer.
The Journal of biological chemistry 2003;278(15):13159-65.
2003: Nikola Kaludov; Eric Padron; Lakshmanan Govindasamy; Robert McKenna; John A Chiorini; Mavis Agbandje-McKenna
Production, purification and preliminary X-ray crystallographic studies of adeno-associated virus serotype 4.
Virology 2003;306(1):1-6.
2003: David M Duda; Lakshmanan Govindasamy; Mavis Agbandje-McKenna; Chingkuang Tu; David N Silverman; Robert McKenna
The refined atomic structure of carbonic anhydrase II at 1.05 A resolution: implications of chemical rescue of proton transfer.
Acta crystallographica. Section D, Biological crystallography 2003;59(Pt 1):93-104.
2002: Robbie Reutzel; Susan K Boehlein; Lakshmanan Govindasamy; Ryan B Brenes; Mavis Agbandje-McKenna; Sheldon M Schuster; Robert McKenna
Crystallization and preliminary X-ray analysis of the tumor metastasis factor p37.
Acta crystallographica. Section D, Biological crystallography 2002;58(Pt 12):2141-4.
2002: Chingkuang Tu; Minzhang Qian; Haiqian An; Nina R Wadhwa; David M Duda; Craig Yoshioka; Yashash Pathak; Robert McKenna; Philip J Laipis; David N Silverman
Kinetic analysis of multiple proton shuttles in the active site of human carbonic anhydrase.
The Journal of biological chemistry 2002;277(41):38870-6.
2002: Wei Lian; Lakshmanan Govindasamy; Yunrong Gu; Thomas Kukar; Mavis Agbandje-McKenna; Robert McKenna; Donghai Wu
Crystallization and preliminary X-ray crystallographic studies on recombinant human carnitine acetyltransferase.
Acta crystallographica. Section D, Biological crystallography 2002;58(Pt 7):1193-4.
2002: michael bubb; Lakshmanan Govindasamy; Elena G Yarmola; Sergey M Vorobiev; Steven C Almo; Thayumanasamy Somasundaram; Michael S Chapman; Mavis Agbandje-McKenna; Robert McKenna
Polylysine induces an antiparallel actin dimer that nucleates filament assembly: crystal structure at 3.5-A resolution.
The Journal of biological chemistry 2002;277(23):20999-1006.
2002: David M Duda; Craig Yoshioka; Lakshmanan Govindasamy; Haiqian An; Chingkuang Tu; David N Silverman; Robert McKenna
Crystallization and preliminary X-ray analysis of human carbonic anhydrase III.
Acta crystallographica. Section D, Biological crystallography 2002;58(Pt 5):849-52.
2002: Haiqian An; Chingkuang Tu; David M Duda; Ileana Montanez-Clemente; Kristen Math; Philip J Laipis; Robert McKenna; David N Silverman
Chemical rescue in catalysis by human carbonic anhydrases II and III.
Biochemistry 2002;41(9):3235-42.
2002: Karie L Brentlinger; Susan Hafenstein; Christopher R Novak; Bentley A Fane; Robert Borgon; Robert McKenna; Mavis Agbandje-McKenna
Microviridae, a family divided: isolation, characterization, and genome sequence of phiMH2K, a bacteriophage of the obligate intracellular parasitic bacterium Bdellovibrio bacteriovorus.
Journal of bacteriology 2002;184(4):1089-94.
2001: David M Duda; Chingkuang Tu; Minzhang Qian; Philip J Laipis; Mavis Agbandje-McKenna; David N Silverman; Robert McKenna
Structural and kinetic analysis of the chemical rescue of the proton transfer function of carbonic anhydrase II.
Biochemistry 2001;40(6):1741-8.
2001: Wei Zhang; Norman H Olson; Timothy S Baker; L Faulkner; Mavis Agbandje-McKenna; Margaret I Boulton; JW Davies; Robert McKenna
Structure of the Maize streak virus geminate particle.
Virology 2001;279(2):471-7.
2000: Eva Hernando; Antonio Luis Llamas-Saiz; Concepción Foces-Foces; Robert McKenna; I Portman; Mavis Agbandje-McKenna; José M Almendral
Biochemical and physical characterization of parvovirus minute virus of mice virus-like particles.
Virology 2000;267(2):299-309.
1998: T Dokland; Robert McKenna; Debra M Sherman; B R Bowman; W F Bean; Michael G Rossmann
Structure determination of the phiX174 closed procapsid.
Acta crystallographica. Section D, Biological crystallography 1998;54(Pt 5):878-90.
1998: Paul R Chipman; Mavis Agbandje-McKenna; J Renaudin; Timothy S Baker; Robert McKenna
Structural analysis of the Spiroplasma virus, SpV4: implications for evolutionary variation to obtain host diversity among the Microviridae.
Structure (London, England : 1993) 1998;6(2):135-45.
1997: T Dokland; Robert McKenna; L L Ilag; B R Bowman; N L Incardona; Bentley A Fane; Michael G Rossmann
Structure of a viral procapsid with molecular scaffolding.
Nature 1997;389(6648):308-13.
1996: Robert McKenna; B R Bowman; L L Ilag; Michael G Rossmann; Bentley A Fane
Atomic structure of the degraded procapsid particle of the bacteriophage G4: induced structural changes in the presence of calcium ions and functional implications.
Journal of molecular biology 1996;256(4):736-50.
1995: L L Ilag; Norman H Olson; T Dokland; C L Music; R Holland Cheng; Z Bowen; Robert McKenna; Michael G Rossmann; Timothy S Baker; N L Incardona
DNA packaging intermediates of bacteriophage phi X174.
Structure (London, England : 1993) 1995;3(4):353-63.
1994: L L Ilag; Robert McKenna; M P Yadav; J N BeMiller; N L Incardona; Michael G Rossmann
Calcium ion-induced structural changes in bacteriophage phi X174.
Journal of molecular biology 1994;244(3):291-300.
1994: Robert McKenna; L L Ilag; Michael G Rossmann
Analysis of the single-stranded DNA bacteriophage phi X174, refined at a resolution of 3.0 A.
Journal of molecular biology 1994;237(5):517-43.
1992: Robert McKenna; D Xia; P Willingmann; L L Ilag; Michael G Rossmann
Structure determination of the bacteriophage phiX174.
Acta crystallographica. Section B, Structural science 1992;48 ( Pt 4)():499-511.
1992: Robert McKenna; D Xia; P Willingmann; L L Ilag; S Krishnaswamy; Michael G Rossmann; Norman H Olson; Timothy S Baker; N L Incardona
Atomic structure of single-stranded DNA bacteriophage phi X174 and its functional implications.
Nature 1992;355(6356):137-43.
1990: P Willingmann; S Krishnaswamy; Robert McKenna; Thomas J Smith; Norman H Olson; Michael G Rossmann; P L Stow; N L Incardona
Preliminary investigation of the phage phi X174 crystal structure.
Journal of molecular biology 1990;212(2):345-50.