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Gillies McKenna

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Emmanouil Fokas; W Gillies McKenna; Ruth J Muschel
The impact of tumor microenvironment on cancer treatment and its modulation by direct and indirect antivascular strategies.
Nils H Nicolay; Remko Prevo; Niklas Schultz; Rebecca Carter; Stephanie B Hatch; Thomas Helleday; W Gillies McKenna; Ricky A Sharma
Homologous recombination mediates S-phase-dependent radioresistance in cells deficient in DNA polymerase eta.
Remko Prevo; Philip M Reaper; Peter A Charlton; Emmanouil Fokas; W Gillies McKenna; Ruth J Muschel; John R Pollard; Thomas B Brunner
The novel ATR inhibitor VE-821 increases sensitivity of pancreatic cancer cells to radiation and chemotherapy.

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All Publications

2012: Emmanouil Fokas; W Gillies McKenna; Ruth J Muschel
The impact of tumor microenvironment on cancer treatment and its modulation by direct and indirect antivascular strategies.
Cancer metastasis reviews 2012;31(3-4):823-42.
2012: Nils H Nicolay; Remko Prevo; Niklas Schultz; Rebecca Carter; Stephanie B Hatch; Thomas Helleday; W Gillies McKenna; Ricky A Sharma
Homologous recombination mediates S-phase-dependent radioresistance in cells deficient in DNA polymerase eta.
Carcinogenesis 2012;33(11):2026-34.
2012: Remko Prevo; Philip M Reaper; Peter A Charlton; Emmanouil Fokas; W Gillies McKenna; Ruth J Muschel; John R Pollard; Thomas B Brunner
The novel ATR inhibitor VE-821 increases sensitivity of pancreatic cancer cells to radiation and chemotherapy.
Cancer biology & therapy 2012;13(11):1072-81.
2012: Hiroshi Harada; Kiichi Hirota; Masahiro Inoue; Satoshi Itasaka; W Gillies McKenna; Akiyo Morinibu; Ruth J Muschel; Guangfei Ou; Kazumi Shinomiya; Michio Yoshimura; Lihua Zeng; Yuxi Zhu; Masahiro Hiraoka
Cancer cells that survive radiation therapy acquire HIF-1 activity and translocate towards tumour blood vessels.
Nature communications 2012;3():783.
2012: Emmanouil Fokas; Wolfgang Hackl; Geoff Higgins; Sauveur-Michel Maira; W Gillies McKenna; Remko Prevo; Michio Yoshimura; Eric J Bernhard; Ruth J Muschel
NVP-BEZ235 and NVP-BGT226, dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitors, enhance tumor and endothelial cell radiosensitivity.
Radiation oncology (London, England) 2012;7():48.
2010: Geoff S Higgins; Adrian L Harris; Remko Prevo; Thomas Helleday; W Gillies McKenna; Francesca M Buffa
Overexpression of POLQ confers a poor prognosis in early breast cancer patients.
Oncotarget 2010;1(3):175-84.
2010: Geoff S Higgins; Remko Prevo; Yin-Fai Lee; Thomas Helleday; Ruth J Muschel; Steve Taylor; Michio Yoshimura; Ian D Hickson; Eric J Bernhard; W Gillies McKenna
A small interfering RNA screen of genes involved in DNA repair identifies tumor-specific radiosensitization by POLQ knockdown.
Cancer research 2010;70(7):2984-93.
2010: J Yang; J Parsons; N H Nicolay; S Caporali; Chris Harrington; Rajinder Singh; D Finch; S D'Atri; P B Farmer; P G Johnston; W Gillies McKenna; Grigory L Dianov; Ricky A Sharma
Cells deficient in the base excision repair protein, DNA polymerase beta, are hypersensitive to oxaliplatin chemotherapy.
Oncogene 2010;29(3):463-8.
2009: Osama Al-Assar; Ruth J Muschel; Tine S Mantoni; W Gillies McKenna; Thomas B Brunner
Radiation response of cancer stem-like cells from established human cell lines after sorting for surface markers.
International journal of radiation oncology, biology, physics 2009;75(4):1216-25.
2009: Jason L Parsons; Phillip S Tait; David Finch; Irina I Dianova; Mariola J Edelmann; Svetlana V Khoronenkova; Benedikt M Kessler; Ricky A Sharma; W Gillies McKenna; Grigory L Dianov
Ubiquitin ligase ARF-BP1/Mule modulates base excision repair.
The EMBO journal 2009;28(20):3207-15.
2009: Naseer Qayum; Ruth J Muschel; Jae Hong Im; Lukxmi Balathasan; Cameron J Koch; Sonal Patel; W Gillies McKenna; Eric J Bernhard
Tumor vascular changes mediated by inhibition of oncogenic signaling.
Cancer research 2009;69(15):6347-54.
2008: Remko Prevo; Eric Deutsch; Oliver Sampson; Julie Diplexcito; Keith Cengel; Jane Harper; Peter O'Neill; W Gillies McKenna; Sonal Patel; Eric J Bernhard
Class I PI3 kinase inhibition by the pyridinylfuranopyrimidine inhibitor PI-103 enhances tumor radiosensitivity.
Cancer research 2008;68(14):5915-23.
2008: Thomas B Brunner; Matthias Geiger; Gerhard G Grabenbauer; Marga Lang-Welzenbach; Tine S Mantoni; Alexander Cavallaro; Rolf Sauer; Werner Hohenberger; W Gillies McKenna
Phase I trial of the human immunodeficiency virus protease inhibitor nelfinavir and chemoradiation for locally advanced pancreatic cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2008;26(16):2699-706.
2007: Nils Cordes; S Frick; T B Brunner; Christian Pilarsky; Robert Grützmann; Bence Sipos; Günter Klöppel; W Gillies McKenna; Eric J Bernhard
Human pancreatic tumor cells are sensitized to ionizing radiation by knockdown of caveolin-1.
Oncogene 2007;26(48):6851-62.
2007: Keith A. Cengel; K Ranh Voong; Sanjay Chandrasekaran; Laurence Maggiorella; Thomas B Brunner; Eric Stanbridge; Gary D Kao; W Gillies McKenna; Eric J Bernhard
Oncogenic K-Ras signals through epidermal growth factor receptor and wild-type H-Ras to promote radiation survival in pancreatic and colorectal carcinoma cells.
Neoplasia (New York, N.Y.) 2007;9(4):341-8.
2005: Thomas B Brunner; Keith A. Cengel; Stephen M Hahn; Junmin Wu; Douglas L Fraker; W Gillies McKenna; Eric J Bernhard
Pancreatic cancer cell radiation survival and prenyltransferase inhibition: the role of K-Ras.
Cancer research 2005;65(18):8433-41.
2005: Anjali K Gupta; george cerniglia; Rosemarie Mick; W Gillies McKenna; Ruth J Muschel
HIV protease inhibitors block Akt signaling and radiosensitize tumor cells both in vitro and in vivo.
Cancer research 2005;65(18):8256-65.
2005: In Ah Kim; Sun Sik Bae; Annemarie Fernandes; Junmin Wu; Ruth J Muschel; W Gillies McKenna; Morris J Birnbaum; Eric J Bernhard
Selective inhibition of Ras, phosphoinositide 3 kinase, and Akt isoforms increases the radiosensitivity of human carcinoma cell lines.
Cancer research 2005;65(17):7902-10.
2005: Keith A. Cengel; W Gillies McKenna
Molecular targets for altering radiosensitivity: lessons from Ras as a pre-clinical and clinical model.
Critical reviews in oncology/hematology 2005;55(2):103-16.
2005: Niklas Finnberg; Joshua J Gruber; Peiwen Fei; Dorothea Rudolph; Anka Bric; Seok-Hyun Kim; Timothy F Burns; Hope Ajuha; Robert Page; Gen Sheng Wu; Youhai Chen; W Gillies McKenna; Eric J Bernhard; Scott W Lowe; Tak Mak; Wafik S El-Deiry
DR5 knockout mice are compromised in radiation-induced apoptosis.
Molecular and cellular biology 2005;25(5):2000-13.
2004: Peiwen Fei; Wenge Wang; Seok-hyun Kim; Shulin Wang; Timothy F Burns; Joanna K Sax; Monica Buzzai; David T Dicker; W Gillies McKenna; Eric J Bernhard; Wafik S El-Deiry
Bnip3L is induced by p53 under hypoxia, and its knockdown promotes tumor growth.
Cancer cell 2004;6(6):597-609.
2004: Thomas B Brunner; Stephen M Hahn; W Gillies McKenna; Eric J Bernhard
Radiation sensitization by inhibition of activated Ras.
Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al] 2004;180(11):731-40.
2004: Neil E Martin; Thomas B Brunner; Krystyna Kiel; Thomas F DeLaney; William F Regine; Mohammed Mohiuddin; Ernest F Rosato; Daniel G Haller; James P Stevenson; Debbie Smith; Barnali Pramanik; Joel E Tepper; Wesley K Tanaka; Briggs Morrison; Paul Deutsch; Anjali K Gupta; Ruth J Muschel; W Gillies McKenna; Eric J Bernhard; Stephen M Hahn
A phase I trial of the dual farnesyltransferase and geranylgeranyltransferase inhibitor L-778,123 and radiotherapy for locally advanced pancreatic cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(16):5447-54.
2004: Gary D Kao; W Gillies McKenna
"Hood ornament" or "V-10 engine"? Myths and realities regarding physician-scientists in academic radiation oncology departments.
Journal of the American College of Radiology : JACR 2004;1(8):539-44.
2004: In Ah Kim; Annemarie T Fernandes; Anjali K Gupta; W Gillies McKenna; Eric J Bernhard
The influence of Ras pathway signaling on tumor radiosensitivity.
Cancer metastasis reviews 2004;23(3-4):227-36.
2004: Anjali K Gupta; Daniel E Soto; Michael D Feldman; Jeffrey D Goldsmith; Rosemarie Mick; Stephen M Hahn; Mitchell Machtay; Ruth J Muschel; W Gillies McKenna
Signaling pathways in NSCLC as a predictor of outcome and response to therapy.
Lung 2004;182(3):151-62.
2003: C Norman Coleman; Helen B Stone; George A Alexander; Mary Helen Barcellos-Hoff; Joel S Bedford; Robert G Bristow; Joseph R Dynlacht; Zvi Fuks; Lester S Gorelic; Richard P Hill; Michael Charles Joiner; Fei-Fei Liu; william mcbride; W Gillies McKenna; Simon Nicholas Powell; Mike E Robbins; Sara Rockwell; Peter B Schiff; Edward G Shaw; Dietmar W Siemann; Elizabeth L Travis; Paul E Wallner; Rosemary S L Wong; Elaine Zeman
Education and training for radiation scientists: radiation research program and American Society of Therapeutic Radiology and Oncology Workshop, Bethesda, Maryland, May 12-14, 2003.
Radiation research 2003;160(6):729-37.
2003: W Gillies McKenna; Ruth J Muschel
Targeting tumor cells by enhancing radiation sensitivity.
Genes, chromosomes & cancer 2003;38(4):330-8.
2003: Bin Li; Chi-Ming Chang; Min Yuan; W Gillies McKenna; Hui-Kuo G Shu
Resistance to small molecule inhibitors of epidermal growth factor receptor in malignant gliomas.
Cancer research 2003;63(21):7443-50.
2003: Thomas B Brunner; Stephen M Hahn; Anjali K Gupta; Ruth J Muschel; W Gillies McKenna; Eric J Bernhard
Farnesyltransferase inhibitors: an overview of the results of preclinical and clinical investigations.
Cancer research 2003;63(18):5656-68.
2003: W Gillies McKenna; Ruth J Muschel; Anjali K Gupta; Stephen M Hahn; Eric J Bernhard
The RAS signal transduction pathway and its role in radiation sensitivity.
Oncogene 2003;22(37):5866-75.
2003: Thomas B Brunner; Anjali K Gupta; Yuquan Shi; Stephen M Hahn; Ruth J Muschel; W Gillies McKenna; Eric J Bernhard
Farnesyltransferase inhibitors as radiation sensitizers.
International journal of radiation biology 2003;79(7):569-76.
2003: Jeremy Sugarman; W Gillies McKenna
Ethical hurdles for translational research.
Radiation research 2003;160(1):1-4.
2003: Anjali K Gupta; george cerniglia; Rosemarie Mick; Mona S Ahmed; Vincent J Bakanauskas; Ruth J Muschel; W Gillies McKenna
Radiation sensitization of human cancer cells in vivo by inhibiting the activity of PI3K using LY294002.
International journal of radiation oncology, biology, physics 2003;56(3):846-53.
2003: M Ahmad Chaudhry; Lewis A Chodosh; W Gillies McKenna; Ruth J Muschel
Gene expression profile of human cells irradiated in G1 and G2 phases of cell cycle.
Cancer letters 2003;195(2):221-33.
2003: W Gillies McKenna; Ruth J Muschel; Anjali Gupta; Stephen Hahn; Eric J Bernhard
Signaling inhibition with radiation in colorectal cancer: clinical trials.
Seminars in oncology 2003;30(3 Suppl 6):56-67.
2003: Gary D Kao; W Gillies McKenna; Matthew G Guenther; Ruth J Muschel; Mitchell Lazar; Tim J Yen
Histone deacetylase 4 interacts with 53BP1 to mediate the DNA damage response.
The Journal of cell biology 2003;160(7):1017-27.
2003: Intae Lee; Jerry D Glickson; Mark Dewhirst; Dennis B Leeper; Randy Burd; harish poptani; Lydie Nadal; W Gillies McKenna; John E Biaglow
Effect of mild hyperglycemia +/- meta-iodo-benzylguanidine on the radiation response of R3230 Ac tumors.
Advances in experimental medicine and biology 2003;530():177-86.
2002: W Gillies McKenna; Ruth J Muschel; Anjali K Gupta; Stephen M Hahn; Eric J Bernhard
Farnesyltransferase inhibitors as radiation sensitizers.
Seminars in radiation oncology 2002;12(3 Suppl 2):27-32.
2002: Stephen M Hahn; Eric J Bernhard; William F Regine; Mohammed Mohiuddin; Daniel G Haller; James P Stevenson; Debbie Smith; Barnali Pramanik; Joel E Tepper; Thomas F DeLaney; Krystyna Kiel; Briggs Morrison; Paul Deutsch; Ruth J Muschel; W Gillies McKenna
A Phase I trial of the farnesyltransferase inhibitor L-778,123 and radiotherapy for locally advanced lung and head and neck cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(5):1065-72.
2002: M Ahmad Chaudhry; Lewis A Chodosh; W Gillies McKenna; Ruth J Muschel
Gene expression profiling of HeLa cells in G1 or G2 phases.
Oncogene 2002;21(12):1934-42.
2002: Anjali K Gupta; W Gillies McKenna; Charles N Weber; Michael D Feldman; Jeffrey D Goldsmith; Rosemarie Mick; Mitchell Machtay; David I Rosenthal; Vincent J Bakanauskas; george cerniglia; Eric J Bernhard; Randal S Weber; Ruth J Muschel
Local recurrence in head and neck cancer: relationship to radiation resistance and signal transduction.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(3):885-92.
2001: Stephen M Hahn; Eric J Bernhard; W Gillies McKenna
Farnesyltransferase inhibitors.
Seminars in oncology 2001;28(5 Suppl 16):86-93.
2001: Heather A Jones; Stephen M Hahn; Eric J Bernhard; W Gillies McKenna
Ras inhibitors and radiation therapy.
Seminars in radiation oncology 2001;11(4):328-37.
2001: Cameron J Koch; Stephen M Hahn; Kenneth Rockwell; J M Covey; W Gillies McKenna; Sydney Evans
Pharmacokinetics of EF5 [2-(2-nitro-1-H-imidazol-1-yl)-N-(2,2,3,3,3-pentafluoropropyl) acetamide] in human patients: implications for hypoxia measurements in vivo by 2-nitroimidazoles.
Cancer chemotherapy and pharmacology 2001;48(3):177-87.
2001: S Bruce Malkowicz; W Gillies McKenna; David J Vaughn; X Steven Wan; K J Propert; Kenneth Rockwell; S H Marks; Alan J Wein; Ann R Kennedy
Effects of Bowman-Birk inhibitor concentrate (BBIC) in patients with benign prostatic hyperplasia.
The Prostate 2001;48(1):16-28.
2001: Gary D Kao; W Gillies McKenna; Tim J Yen
Detection of repair activity during the DNA damage-induced G2 delay in human cancer cells.
Oncogene 2001;20(27):3486-96.
2001: Anjali K Gupta; Vincent J Bakanauskas; george cerniglia; Y Cheng; Eric J Bernhard; Ruth J Muschel; W Gillies McKenna
The Ras radiation resistance pathway.
Cancer research 2001;61(10):4278-82.
2001: Elizabeth Cohen-Jonathan; Sydney Evans; Cameron J Koch; Ruth J Muschel; W Gillies McKenna; Junmin Wu; Eric J Bernhard
The farnesyltransferase inhibitor L744,832 reduces hypoxia in tumors expressing activated H-ras.
Cancer research 2001;61(5):2289-93.
2001: Sydney Evans; Stephen M Hahn; Deirdre P Magarelli; Paul J Zhang; W Timothy Jenkins; Douglas L Fraker; R Alex Hsi; W Gillies McKenna; Cameron J Koch
Hypoxia in human intraperitoneal and extremity sarcomas.
International journal of radiation oncology, biology, physics 2001;49(2):587-96.
2001: Anjali K Gupta; Vincent J Bakanauskas; W Gillies McKenna; Eric J Bernhard; Ruth J Muschel
Ras regulation of radioresistance in cell culture.
Methods in enzymology 2001;333():284-90.
2001: Anna Janss; Amit Maity; CB Tang; Ruth J Muschel; W Gillies McKenna; L Sutton; Peter C Phillips
Decreased cyclin B1 expression contributes to G2 delay in human brain tumor cells after treatment with camptothecin.
Neuro-oncology 2001;3(1):11-21.
2000: Eric J Bernhard; E J Stanbridge; S Gupta; Anjali K Gupta; Daniel E Soto; Vincent J Bakanauskas; george cerniglia; Ruth J Muschel; W Gillies McKenna
Direct evidence for the contribution of activated N-ras and K-ras oncogenes to increased intrinsic radiation resistance in human tumor cell lines.
Cancer research 2000;60(23):6597-600.
2000: Theodore J Robnett; Mitchell Machtay; E F Vines; MG McKenna; Kenneth M Algazy; W Gillies McKenna
Factors predicting severe radiation pneumonitis in patients receiving definitive chemoradiation for lung cancer.
International journal of radiation oncology, biology, physics 2000;48(1):89-94.
2000: Anjali K Gupta; Eric J Bernhard; Vincent J Bakanauskas; J Wu; Ruth J Muschel; W Gillies McKenna
RAS-Mediated radiation resistance is not linked to MAP kinase activation in two bladder carcinoma cell lines.
Radiation research 2000;154(1):64-72.
2000: Sydney Evans; S Hahn; D R Pook; W Timothy Jenkins; Ara A Chalian; Paul Zhang; C Stevens; R Weber; Gregory Weinstein; I Benjamin; Natasha Mirza; M Morgan; S Rubin; W Gillies McKenna; EM Lord; Cameron J Koch
Detection of hypoxia in human squamous cell carcinoma by EF5 binding.
Cancer research 2000;60(7):2018-24.
2000: Iraimoudi S Ayene; Eric J Bernhard; W Gillies McKenna; Ruth J Muschel; Robert E Krisch; Cameron J Koch
DNA as an important target in radiation-induced apoptosis of MYC and MYC plus RAS transfected rat embryo fibroblasts.
International journal of radiation biology 2000;76(3):343-54.
1999: Gary D Kao; W Gillies McKenna; Ruth J Muschel
p34(Cdc2) kinase activity is excluded from the nucleus during the radiation-induced G(2) arrest in HeLa cells.
The Journal of biological chemistry 1999;274(49):34779-84.
1999: JH Lee; Mitchell Machtay; Larry R Kaiser; J S Friedberg; Stephen M Hahn; MG McKenna; W Gillies McKenna
Non-small cell lung cancer: prognostic factors in patients treated with surgery and postoperative radiation therapy.
Radiology 1999;213(3):845-52.
1999: Eric J Bernhard; W Gillies McKenna; R J Muschel
Radiosensitivity and the cell cycle.
The cancer journal from Scientific American 1999;5(4):194-204.
1999: E C Jonathan; Eric J Bernhard; W Gillies McKenna
How does radiation kill cells?
Current opinion in chemical biology 1999;3(1):77-83.
1998: Ruth J Muschel; Daniel E Soto; W Gillies McKenna; Eric J Bernhard
Radiosensitization and apoptosis.
Oncogene 1998;17(25):3359-63.
1998: A Hwang; W Gillies McKenna; Ruth J Muschel
Cell cycle-dependent usage of transcriptional start sites. A novel mechanism for regulation of cyclin B1.
The Journal of biological chemistry 1998;273(47):31505-9.
1998: John E Biaglow; Cameron J Koch; Stephen W Tuttle; Yefim Manevich; Iraimoudi S Ayene; Eric J Bernhard; W Gillies McKenna; Alexander V Kachur
The measurement of bioreductive capacity of tumor cells using methylene blue.
International journal of radiation oncology, biology, physics 1998;42(4):769-73.
1998: Anna Janss; C Levow; Eric J Bernhard; Ruth J Muschel; W Gillies McKenna; L Sutton; Peter C Phillips
Caffeine and staurosporine enhance the cytotoxicity of cisplatin and camptothecin in human brain tumor cell lines.
Experimental cell research 1998;243(1):29-38.
1998: R A Barratt; Gary D Kao; W Gillies McKenna; Jian Kuang; Ruth J Muschel
The G2 block induced by DNA damage: a caffeine-resistant component independent of Cdc25C, MPM-2 phosphorylation, and H1 kinase activity.
Cancer research 1998;58(12):2639-45.
1998: Eric J Bernhard; W Gillies McKenna; Andrew D Hamilton; Said M Sebti; Y Qian; J M Wu; Ruth J Muschel
Inhibiting Ras prenylation increases the radiosensitivity of human tumor cell lines with activating mutations of ras oncogenes.
Cancer research 1998;58(8):1754-61.
1998: Eleanor E R Harris; Gary D Kao; Ruth J Muschel; W Gillies McKenna
Potential applications of cell cycle manipulation to clinical response.
Cancer treatment and research 1998;93():169-90.
1997: KR Blank; MS Rudoltz; Gary D Kao; Ruth J Muschel; W Gillies McKenna
The molecular regulation of apoptosis and implications for radiation oncology.
International journal of radiation biology 1997;71(5):455-66.
1997: Amit Maity; W Gillies McKenna; Ruth J Muschel
Cyclin A message stability varies with the cell cycle.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1997;8(3):311-8.
1997: Gary D Kao; W Gillies McKenna; Amit Maity; KR Blank; Ruth J Muschel
Cyclin B1 availability is a rate-limiting component of the radiation-induced G2 delay in HeLa cells.
Cancer research 1997;57(4):753-8.
1997: Amit Maity; Gary D Kao; Ruth J Muschel; W Gillies McKenna
Potential molecular targets for manipulating the radiation response.
International journal of radiation oncology, biology, physics 1997;37(3):639-53.
1997: Ruth J Muschel; W Gillies McKenna; Eric J Bernhard
Cell cycle checkpoints and apoptosis: potential for improving radiation therapy.
Vitamins and hormones 1997;53():1-25.
1996: Amit Maity; A Hwang; Anna Janss; P Phillips; W Gillies McKenna; Ruth J Muschel
Delayed cyclin B1 expression during the G2 arrest following DNA damage.
Oncogene 1996;13(8):1647-57.
1996: Stephen W Tuttle; Ruth J Muschel; Eric J Bernhard; W Gillies McKenna; John E Biaglow
Decreased ability of cells overexpressing MYC proteins to reduce peroxide and hydroperoxides.
The British journal of cancer. Supplement 1996;27():S140-44.
1996: Eric J Bernhard; Ruth J Muschel; V J Bakanauskas; W Gillies McKenna
Reducing the radiation-induced G2 delay causes HeLa cells to undergo apoptosis instead of mitotic death.
International journal of radiation biology 1996;69(5):575-84.
1996: Eric J Bernhard; Gary D Kao; Adrienne D Cox; Said M Sebti; Andrew D Hamilton; Ruth J Muschel; W Gillies McKenna
The farnesyltransferase inhibitor FTI-277 radiosensitizes H-ras-transformed rat embryo fibroblasts.
Cancer research 1996;56(8):1727-30.
1996: W Gillies McKenna; Eric J Bernhard; D A Markiewicz; MS Rudoltz; Amit Maity; Ruth J Muschel
Regulation of radiation-induced apoptosis in oncogene-transfected fibroblasts: influence of H-ras on the G2 delay.
Oncogene 1996;12(2):237-45.
1995: A Hwang; Amit Maity; W Gillies McKenna; Ruth J Muschel
Cell cycle-dependent regulation of the cyclin B1 promoter.
The Journal of biological chemistry 1995;270(47):28419-24.
1995: Eric J Bernhard; Amit Maity; Ruth J Muschel; W Gillies McKenna
Effects of ionizing radiation on cell cycle progression. A review.
Radiation and environmental biophysics 1995;34(2):79-83.
1995: Ruth J Muschel; Eric J Bernhard; Luis Garza; W Gillies McKenna; Cameron J Koch
Induction of apoptosis at different oxygen tensions: evidence that oxygen radicals do not mediate apoptotic signaling.
Cancer research 1995;55(5):995-8.
1995: Amit Maity; W Gillies McKenna; Ruth J Muschel
Evidence for post-transcriptional regulation of cyclin B1 mRNA in the cell cycle and following irradiation in HeLa cells.
The EMBO journal 1995;14(3):603-9.
1994: Eric J Bernhard; Amit Maity; Ruth J Muschel; W Gillies McKenna
Increased expression of cyclin B1 mRNA coincides with diminished G2-phase arrest in irradiated HeLa cells treated with staurosporine or caffeine.
Radiation research 1994;140(3):393-400.
1994: Anthony V D'Amico; W Gillies McKenna
Apoptosis and a re-investigation of the biologic basis for cancer therapy.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 1994;33(1):3-10.
1994: Amit Maity; W Gillies McKenna; D A Markiewicz; A Kunig; Ruth J Muschel
Alternate polyadenylation in rodent cells results in two differentially expressed cyclin B1 mRNAs.
Biochemical and biophysical research communications 1994;202(2):908-14.
1994: Eric J Bernhard; W Gillies McKenna; Ruth J Muschel
Cyclin expression and G2-phase delay after irradiation.
Radiation research 1994;138(1 Suppl):S64-7.
1994: Amit Maity; W Gillies McKenna; Ruth J Muschel
The molecular basis for cell cycle delays following ionizing radiation: a review.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 1994;31(1):1-13.
1994: D A Markiewicz; W Gillies McKenna; M B Flick; Amit Maity; Ruth J Muschel
The effects of radiation on the expression of a newly cloned and characterized rat cyclin B mRNA.
International journal of radiation oncology, biology, physics 1994;28(1):135-44.
1993: Ruth J Muschel; H B Zhang; W Gillies McKenna
Differential effect of ionizing radiation on the expression of cyclin A and cyclin B in HeLa cells.
Cancer research 1993;53(5):1128-35.
1992: Ruth J Muschel; H B Zhang; G Iliakis; W Gillies McKenna
Effects of ionizing radiation on cyclin expression in HeLa cells.
Radiation research 1992;132(2):153-7.
1991: Ruth J Muschel; H B Zhang; G Iliakis; W Gillies McKenna
Cyclin B expression in HeLa cells during the G2 block induced by ionizing radiation.
Cancer research 1991;51(19):5113-7.
1991: W Gillies McKenna; G Iliakis; M C Weiss; Eric J Bernhard; Ruth J Muschel
Increased G2 delay in radiation-resistant cells obtained by transformation of primary rat embryo cells with the oncogenes H-ras and v-myc.
Radiation research 1991;125(3):283-7.
1990: W Gillies McKenna; M C Weiss; V J Bakanauskas; H Sandler; M L Kelsten; John E Biaglow; Stephen W Tuttle; B Endlich; C Clifton Ling; Ruth J Muschel
The role of the H-ras oncogene in radiation resistance and metastasis.
International journal of radiation oncology, biology, physics 1990;18(4):849-59.
1990: W Gillies McKenna; M C Weiss; B Endlich; C Clifton Ling; V J Bakanauskas; M L Kelsten; Ruth J Muschel
Synergistic effect of the v-myc oncogene with H-ras on radioresistance.
Cancer research 1990;50(1):97-102.
1989: Ruth J Muschel; W Gillies McKenna
Oncogenes and tumor progression.
Anticancer research 1989;9(5):1395-406.
1988: W Gillies McKenna; K Nakahara; Ruth J Muschel
Site-specific integration of H-ras in transformed rat embryo cells.
Science (New York, N.Y.) 1988;241(4871):1325-8.