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Andrew McKenzie

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Lucille C Rankin; Jennifer A Walker; Sebastian Carotta; Michaël Chopin; Joanna R Groom; Marco J Herold; Andrew N J McKenzie; Lisa A Mielke; Stephen L Nutt; Gabrielle T Belz
The transcription factor T-bet is essential for the development of NKp46+ innate lymphocytes via the Notch pathway.
Hergen Spits; David Artis; Marco Colonna; James P Di Santo; Andreas Diefenbach; Gerard Eberl; Shigeo Koyasu; Richard M Locksley; Andrew N J McKenzie; Reina E Mebius; Fiona Powrie; Eric Vivier
Innate lymphoid cells--a proposal for uniform nomenclature.
Jennifer A Walker; Jillian L Barlow; Andrew N J McKenzie
Innate lymphoid cells--how did we miss them?

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2013: Lucille C Rankin; Jennifer A Walker; Sebastian Carotta; Michaël Chopin; Joanna R Groom; Marco J Herold; Andrew N J McKenzie; Lisa A Mielke; Stephen L Nutt; Gabrielle T Belz
The transcription factor T-bet is essential for the development of NKp46+ innate lymphocytes via the Notch pathway.
Nature immunology 2013;14(4):389-95.
2013: Hergen Spits; David Artis; Marco Colonna; James P Di Santo; Andreas Diefenbach; Gerard Eberl; Shigeo Koyasu; Richard M Locksley; Andrew N J McKenzie; Reina E Mebius; Fiona Powrie; Eric Vivier
Innate lymphoid cells--a proposal for uniform nomenclature.
Nature reviews. Immunology 2013;13(2):145-9.
2013: Jennifer A Walker; Jillian L Barlow; Andrew N J McKenzie
Innate lymphoid cells--how did we miss them?
Nature reviews. Immunology 2013;13(2):75-87.
2013: Clare S Hardman; Veera Panova; Andrew N J McKenzie
IL-33 citrine reporter mice reveal the temporal and spatial expression of IL-33 during allergic lung inflammation.
European journal of immunology 2013;43(2):488-98.
2013: Kristopher J Stanya; Sihao Liu; Andrew N J McKenzie; Joseph P Mizgerd; Ling Qi; Hang Shi; Jillian L Barlow; Prerna Bhargava; Lingling Dai; Matthew R Gangl; Karen Inouye; David Jacobi; Yewei Ji; Chih-Hao Lee
Direct control of hepatic glucose production by interleukin-13 in mice.
The Journal of clinical investigation 2013;123(1):261-71.
2013: You Yi Hwang; Andrew N J McKenzie
Innate lymphoid cells in immunity and disease.
Advances in experimental medicine and biology 2013;785():9-26.
2013: Lisa G Gregory; Carla P Jones; Gaynor A Campbell; Kate H C Gowers; Andrew N J McKenzie; Devika Sawant; Simone A Walker; Clare M Lloyd
IL-25 drives remodelling in allergic airways disease induced by house dust mite.
Thorax 2013;68(1):82-90.
2012: Ana Camelo; Lesley F Drynan; Wei Gao; Daniel R Neill; Richard Pannell; Justin Sprenkle; See Heng Wong; Keely Wrigley; Sarah J Ballantyne; Jillian L Barlow; Andrew N J McKenzie
Blocking IL-25 signalling protects against gut inflammation in a type-2 model of colitis by suppressing nuocyte and NKT derived IL-13.
Journal of gastroenterology 2012;47(11):1198-211.
2012: Irina G Luzina; Andrew N J McKenzie; John C Papadimitriou; Edward Pickering; Nevins W Todd; Phillip H Kang; Pavel Kopach; Virginia Lockatell; Sergei Atamas
Full-length IL-33 promotes inflammation but not Th2 response in vivo in an ST2-independent fashion.
Journal of immunology (Baltimore, Md. : 1950) 2012;189(1):403-10.
2012: Romy Ouziel; Eric Quertinmont; Eric Trépo; Vincent Vercruysse; Andrew N J McKenzie; Christophe Moreno; Marianna Arvanitakis; Delphine Degré; Myriam Delhaye; Pieter Demetter; Jacques Devière; Thierry Gustot; Olivier Le Moine; Arnaud Lemmers
The ST2 pathway is involved in acute pancreatitis: a translational study in humans and mice.
The American journal of pathology 2012;180(6):2330-9.
2012: Zizhen Kang; Mark A Aronica; Jillian L Barlow; Katarzyna Bulek; Jeong-su Do; Muhammet Fatih Gulen; Andrew N J McKenzie; Booki Min; Shadi Swaidani; Chenhui Wang; Weiguo Yin; Xiaoxia Li
Epithelial cell-specific Act1 adaptor mediates interleukin-25-dependent helminth expulsion through expansion of Lin(-)c-Kit(+) innate cell population.
Immunity 2012;36(5):821-33.
2012: See Heng Wong; Daniel R Neill; Veera Panova; Freddy Radtke; Jennifer A Walker; Jillian L Barlow; Ana Camelo; Lesley F Drynan; Padraic G Fallon; Emily Hams; Clare S Hardman; You Yi Hwang; Helen E Jolin; Ute Koch; Andrew N J McKenzie
Transcription factor RORα is critical for nuocyte development.
Nature immunology 2012;13(3):229-36.
2011: Chris J Oliphant; Jillian L Barlow; Andrew N J McKenzie
Insights into the initiation of type 2 immune responses.
Immunology 2011;134(4):378-85.
2011: Jillian L Barlow; Andrew N J McKenzie
Nuocytes: expanding the innate cell repertoire in type-2 immunity.
Journal of leukocyte biology 2011;90(5):867-74.
2011: Ya-Jen Chang; Rosemarie H Dekruyff; Hye Young Kim; Andrew N J McKenzie; Dirk E Smith; Lee A Albacker; Nicole Baumgarth; Dale T Umetsu
Innate lymphoid cells mediate influenza-induced airway hyper-reactivity independently of adaptive immunity.
Nature immunology 2011;12(7):631-8.
2011: Ivan Jovanovic; Nebojsa Arsenijevic; Stipan Jonjic; Andrew N J McKenzie; Maja Mitrovic; Gordana Radosavljevic; Vanda Lisnic Juranic; Miodrag L Lukic
ST2 deletion enhances innate and acquired immunity to murine mammary carcinoma.
European journal of immunology 2011;41(7):1902-12.
2011: J L Barlow; Helen E Jolin; S J Ballantyne; See Heng Wong; Andrew N J McKenzie
Tim1 and Tim3 are not essential for experimental allergic asthma.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2011;41(7):1012-21.
2011: Daniel R Neill; Andrew N J McKenzie
Nuocytes and beyond: new insights into helminth expulsion.
Trends in parasitology 2011;27(5):214-21.
2011: Hendrik J Nel; Emily Hams; Sean P Saunders; Niamh E Mangan; Philip Smith; Ann Atzberger; Richard A Flavell; Shizuo Akira; Andrew N J McKenzie; Padraic G Fallon
Impaired basophil induction leads to an age-dependent innate defect in type 2 immunity during helminth infection in mice.
Journal of immunology (Baltimore, Md. : 1950) 2011;186(8):4631-9.
2011: Mousa Komai-Koma; Derek S Gilchrist; Andrew N J McKenzie; Carl S Goodyear; Damo Xu; Foo Y Liew
IL-33 activates B1 cells and exacerbates contact sensitivity.
Journal of immunology (Baltimore, Md. : 1950) 2011;186(4):2584-91.
2011: Kathrin Eller; Dominik Wolf; Julia M Huber; Martin Metz; Gert Mayer; Andrew N J McKenzie; Marcus Maurer; Alexander R Rosenkranz; Anna M Wolf
IL-9 production by regulatory T cells recruits mast cells that are essential for regulatory T cell-induced immune suppression.
Journal of immunology (Baltimore, Md. : 1950) 2011;186(1):83-91.
2010: Jacqueline Boultwood; Andrea Pellagatti; Andrew N J McKenzie; james wainscoat
Advances in the 5q- syndrome.
Blood 2010;116(26):5803-11.
2010: Jillian L Barlow; Lesley F Drynan; Nicola L Trim; Wendy N Erber; Alan J Warren; Andrew N J McKenzie
New insights into 5q- syndrome as a ribosomopathy.
Cell cycle (Georgetown, Tex.) 2010;9(21):4286-93.
2010: Ashley M Miller; Darren L Asquith; Axel J Hueber; Lesley A Anderson; William M Holmes; Andrew N J McKenzie; Damo Xu; Naveed Sattar; Iain B McInnes; Foo Y Liew
Interleukin-33 induces protective effects in adipose tissue inflammation during obesity in mice.
Circulation research 2010;107(5):650-8.
2010: See Heng Wong; Jillian L Barlow; Stephen Nabarro; Padraic G Fallon; Andrew N J McKenzie
Tim-1 is induced on germinal centre B cells through B-cell receptor signalling but is not essential for the germinal centre response.
Immunology 2010;131(1):77-88.
2010: Daniel R Neill; See Heng Wong; Agustin Bellosi; Robin J Flynn; Maria Daly; Theresa K A Langford; Christine Bucks; Colleen M Kane; Padraic G Fallon; Richard Pannell; Helen E Jolin; Andrew N J McKenzie
Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity.
Nature 2010;464(7293):1367-70.
2010: Andrea Pellagatti; Teresa Marafioti; Jennifer C Paterson; Jillian L Barlow; Lesley F Drynan; Aristoteles Giagounidis; Stefano A Pileri; Mario Cazzola; Andrew N J McKenzie; james wainscoat; Jacqueline Boultwood
Induction of p53 and up-regulation of the p53 pathway in the human 5q- syndrome.
Blood 2010;115(13):2721-3.
2010: Damo Xu; Hui-Rong Jiang; Yubin Li; Peter Natesan Pushparaj; Mariola Kurowska-Stolarska; Bernard P Leung; Rong Mu; Hwee Kee Tay; Andrew N J McKenzie; Iain B McInnes; Alirio J Melendez; Foo Y Liew
IL-33 exacerbates autoantibody-induced arthritis.
Journal of immunology (Baltimore, Md. : 1950) 2010;184(5):2620-6.
2010: Sean P Saunders; Jillian L Barlow; Caitriona M Walsh; Agustin Bellsoi; Philip Smith; Andrew N J McKenzie; Padraic G Fallon
C-type lectin SIGN-R1 has a role in experimental colitis and responsiveness to lipopolysaccharide.
Journal of immunology (Baltimore, Md. : 1950) 2010;184(5):2627-37.
2010: Leigh A Jones; Fiona Roberts; MB Nickdel; Frank Brombacher; Andrew N J McKenzie; Fiona L Henriquez; James Alexander; Craig William Roberts
IL-33 receptor (T1/ST2) signalling is necessary to prevent the development of encephalitis in mice infected with Toxoplasma gondii.
European journal of immunology 2010;40(2):426-36.
2010: Jillian L Barlow; Lesley F Drynan; Duncan R Hewett; Luke R Holmes; Silvia Lorenzo-Abalde; Alison L Lane; Helen E Jolin; Richard Pannell; Angela J Middleton; See Heng Wong; Alan J Warren; james wainscoat; Jacqueline Boultwood; Andrew N J McKenzie
A p53-dependent mechanism underlies macrocytic anemia in a mouse model of human 5q- syndrome.
Nature medicine 2010;16(1):59-66.
2009: Rui He; Hye Young Kim; Juhan Yoon; Michiko K Oyoshi; Andrew MacGinnitie; Sho Goya; Eva-Jasmin Freyschmidt; Paul J Bryce; Andrew N J McKenzie; Dale T Umetsu; Hans C Oettgen; Raif S Geha
Exaggerated IL-17 response to epicutaneous sensitization mediates airway inflammation in the absence of IL-4 and IL-13.
The Journal of allergy and clinical immunology 2009;124(4):761-70.e1.
2009: Quentin Espinassous; Elvira Garcia-de-Paco; Ignacio Garcia-Verdugo; Monique Synguelakis; Sonja Von Aulock; Jean-Michel Sallenave; Andrew N J McKenzie; Jean M Kanellopoulos
IL-33 enhances lipopolysaccharide-induced inflammatory cytokine production from mouse macrophages by regulating lipopolysaccharide receptor complex.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(2):1446-55.
2009: Satoru Fukuyama; Takako Nakano; Takafumi Matsumoto; Brian G G Oliver; Janette K Burgess; Atsushi Moriwaki; Kentaro Tanaka; Masato Kubo; Tomoaki Hoshino; Hiroyuki Tanaka; Andrew N J McKenzie; Koichiro Matsumoto; Hisamichi Aizawa; Yoichi Nakanishi; Akihiko Yoshimura; Judith L Black; Hiromasa Inoue
Pulmonary suppressor of cytokine signaling-1 induced by IL-13 regulates allergic asthma phenotype.
American journal of respiratory and critical care medicine 2009;179(11):992-8.
2009: Sun-Young Oh; Tao Zheng; Yoon-Keun Kim; Lauren Cohn; Robert J Homer; Andrew N J McKenzie; Zhou Zhu
A critical role of SHP-1 in regulation of type 2 inflammation in the lung.
American journal of respiratory cell and molecular biology 2009;40(5):568-74.
2009: Catharina W Wieland; Gerritje J W van der Windt; Sandrine Florquin; Andrew N J McKenzie; Tom van der Poll
ST2 deficient mice display a normal host defense against pulmonary infection with Mycobacterium tuberculosis.
Microbes and infection / Institut Pasteur 2009;11(4):524-30.
2009: Jillian L Barlow; Andrew N J McKenzie
IL-25: a key requirement for the regulation of type-2 immunity.
BioFactors (Oxford, England) 2009;35(2):178-82.
2009: Werner Stenzel; Uwe Müller; Gabriele Köhler; Frank L Heppner; Manfred Blessing; Andrew N J McKenzie; Frank Brombacher; Gottfried Alber
IL-4/IL-13-dependent alternative activation of macrophages but not microglial cells is associated with uncontrolled cerebral cryptococcosis.
The American journal of pathology 2009;174(2):486-96.
2008: Mariola Kurowska-Stolarska; Pete Kewin; Grace Murphy; Remo C Russo; Bartosz Stolarski; Cristiana Couto Garcia; Mousa Komai-Koma; Nick Pitman; Yubin Li; Wanda Niedbala; Andrew N J McKenzie; Mauro M Teixeira; Foo Y Liew; Damo Xu
IL-33 induces antigen-specific IL-5+ T cells and promotes allergic-induced airway inflammation independent of IL-4.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(7):4780-90.
2008: Alison Williams; Puneeta Nath; Sum-Yee Leung; N Khorasani; Andrew N J McKenzie; Ian M Adcock; K Fan Chung
Modulation of ozone-induced airway hyperresponsiveness and inflammation by interleukin-13.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2008;32(3):571-8.
2008: Damo Xu; Hui-Rong Jiang; Peter Kewin; Yubin Li; Rong Mu; Alasdair R Fraser; Nick Pitman; Mariola Kurowska-Stolarska; Andrew N J McKenzie; Iain B McInnes; Foo Y Liew
IL-33 exacerbates antigen-induced arthritis by activating mast cells.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(31):10913-8.
2008: Isao Tawara; Yoshinobu Maeda; Yaping Sun; Kathleen Price Lowler; Chen Liu; Tomomi Toubai; Andrew N J McKenzie; Pavan Reddy
Combined Th2 cytokine deficiency in donor T cells aggravates experimental acute graft-vs-host disease.
Experimental hematology 2008;36(8):988-96.
2007: Sarah J Ballantyne; Jillian L Barlow; Helen E Jolin; Puneeta Nath; Alison Williams; K Fan Chung; Graham Sturton; See Heng Wong; Andrew N J McKenzie
Blocking IL-25 prevents airway hyperresponsiveness in allergic asthma.
The Journal of allergy and clinical immunology 2007;120(6):1324-31.
2007: Uwe Müller; Werner Stenzel; Gabriele Köhler; Christoph Werner; Tobias Polte; Gesine Hansen; Nicole Schütze; Reinhard Straubinger; Manfred Blessing; Andrew N J McKenzie; Frank Brombacher; Gottfried Alber
IL-13 induces disease-promoting type 2 cytokines, alternatively activated macrophages and allergic inflammation during pulmonary infection of mice with Cryptococcus neoformans.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(8):5367-77.
2007: Puneeta Nath; Sum Yee Leung; Alison Williams; Alistair Noble; Shaoping Xie; Andrew N J McKenzie; K Fan Chung
Complete inhibition of allergic airway inflammation and remodelling in quadruple IL-4/5/9/13-/- mice.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2007;37(10):1427-35.
2007: Mousa Komai-Koma; Damo Xu; Yubin Li; Andrew N J McKenzie; Iain B McInnes; Foo Y Liew
IL-33 is a chemoattractant for human Th2 cells.
European journal of immunology 2007;37(10):2779-86.
2007: Walid T Khaled; Eliot K C Read; Sandra E Nicholson; Fiona O Baxter; Amelia J Brennan; Paul J Came; Naomi Sprigg; Andrew N J McKenzie; Christine J Watson
The IL-4/IL-13/Stat6 signalling pathway promotes luminal mammary epithelial cell development.
Development (Cambridge, England) 2007;134(15):2739-50.
2007: Shoji Sanada; Daihiko Hakuno; Luke J Higgins; Eric Schreiter; Andrew N J McKenzie; Richard T Lee
IL-33 and ST2 comprise a critical biomechanically induced and cardioprotective signaling system.
The Journal of clinical investigation 2007;117(6):1538-49.
2007: Niamh E Mangan; Ayan Dasvarma; Andrew N J McKenzie; Padraic G Fallon
T1/ST2 expression on Th2 cells negatively regulates allergic pulmonary inflammation.
European journal of immunology 2007;37(5):1302-12.
2007: Philip Smith; Niamh E Mangan; Caitriona M Walsh; Rosie E Fallon; Andrew N J McKenzie; Nico van Rooijen; Padraic G Fallon
Infection with a helminth parasite prevents experimental colitis via a macrophage-mediated mechanism.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(7):4557-66.
2007: Catharina W Wieland; Estella A Koppel; Jeroen den Dunnen; Sandrine Florquin; Andrew N J McKenzie; Yvette van Kooyk; Tom van der Poll; Teunis B H Geijtenbeek
Mice lacking SIGNR1 have stronger T helper 1 responses to Mycobacterium tuberculosis.
Microbes and infection / Institut Pasteur 2007;9(2):134-41.
2006: Go Takayama; Kazuhiko Arima; Taisuke Kanaji; Shuji Toda; Hiroyuki Tanaka; Shunsuke Shoji; Andrew N J McKenzie; Hiroichi Nagai; Takao Hotokebuchi; Kenji Izuhara
Periostin: a novel component of subepithelial fibrosis of bronchial asthma downstream of IL-4 and IL-13 signals.
The Journal of allergy and clinical immunology 2006;118(1):98-104.
2006: Padraic G Fallon; Sarah J Ballantyne; Niamh E Mangan; Jillian L Barlow; Ayan Dasvarma; Duncan R Hewett; Ann McIlgorm; Helen E Jolin; Andrew N J McKenzie
Identification of an interleukin (IL)-25-dependent cell population that provides IL-4, IL-5, and IL-13 at the onset of helminth expulsion.
The Journal of experimental medicine 2006;203(4):1105-16.
2006: Niamh E Mangan; Nico van Rooijen; Andrew N J McKenzie; Padraic G Fallon
Helminth-modified pulmonary immune response protects mice from allergen-induced airway hyperresponsiveness.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(1):138-47.
2005: Philip Smith; Rosie E Fallon; Niamh E Mangan; Caitriona M Walsh; Margarida Saraiva; Jon Sayers; Andrew N J McKenzie; Antonio Alcami; Padraic G Fallon
Schistosoma mansoni secretes a chemokine binding protein with antiinflammatory activity.
The Journal of experimental medicine 2005;202(10):1319-25.
2005: Jocelyn Padilla; Eleen Daley; Anthony Chow; Kesha Robinson; Kaushik Parthasarathi; Andrew N J McKenzie; Thomas Tschernig; Viswanath P Kurup; Debra D Donaldson; Gabriele Grunig
IL-13 regulates the immune response to inhaled antigens.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(12):8097-105.
2005: Duncan R Hewett; Alison L Simons; Niamh E Mangan; Helen E Jolin; Shelia M Green; Padraic G Fallon; Andrew N J McKenzie
Lethal, neonatal ichthyosis with increased proteolytic processing of filaggrin in a mouse model of Netherton syndrome.
Human molecular genetics 2005;14(2):335-46.
2004: Astrid Lanoue; Menna R Clatworthy; Philippa Smith; Sheila Green; Michael J Townsend; Helen E Jolin; Kenneth G C Smith; Padraic G Fallon; Andrew N J McKenzie
SIGN-R1 contributes to protection against lethal pneumococcal infection in mice.
The Journal of experimental medicine 2004;200(11):1383-93.
2004: Alana M Thackray; Andrew N J McKenzie; Michael A Klein; Angus Lauder; Raymond Bujdoso
Accelerated prion disease in the absence of interleukin-10.
Journal of virology 2004;78(24):13697-707.
2004: Niamh E Mangan; Rosie E Fallon; Philip Smith; Nico van Rooijen; Andrew N J McKenzie; Padraic G Fallon
Helminth infection protects mice from anaphylaxis via IL-10-producing B cells.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(10):6346-56.
2004: Philip Smith; Caitriona M Walsh; Niamh E Mangan; Rosie E Fallon; Jon Sayers; Andrew N J McKenzie; Padraic G Fallon
Schistosoma mansoni worms induce anergy of T cells via selective up-regulation of programmed death ligand 1 on macrophages.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(2):1240-8.
2004: Angus J Lauder; Helen E Jolin; Philippa Smith; José G van den Berg; Alison Jones; william wisden; Kenneth G C Smith; Ayan Dasvarma; Padraic G Fallon; Andrew N J McKenzie
Lymphomagenesis, hydronephrosis, and autoantibodies result from dysregulation of IL-9 and are differentially dependent on Th2 cytokines.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(1):113-22.
2004: David Cope; Peer Wulff; Alessandra Oberto; M I Aller; Marco Capogna; Francesco Ferraguti; C Halbsguth; H Hoeger; Helen E Jolin; Alison Jones; Andrew N J McKenzie; Waltraud Ogris; A Poeltl; Saku T Sinkkonen; Olga Vekovischeva; Esa R Korpi; Werner Sieghart; Erwin Sigel; Peter Somogyi; william wisden
Abolition of zolpidem sensitivity in mice with a point mutation in the GABAA receptor gamma2 subunit.
Neuropharmacology 2004;47(1):17-34.
2004: Elizabeth K Brint; Damo Xu; Haiying Liu; Aisling Dunne; Andrew N J McKenzie; Luke A J O'Neill; Foo Y Liew
ST2 is an inhibitor of interleukin 1 receptor and Toll-like receptor 4 signaling and maintains endotoxin tolerance.
Nature immunology 2004;5(4):373-9.
2004: Dianne C Webb; Klaus I Matthaei; Yeping Cai; Andrew N J McKenzie; Paul S Foster
Polymorphisms in IL-4R alpha correlate with airways hyperreactivity, eosinophilia, and Ym protein expression in allergic IL-13-/- mice.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(2):1092-8.
2004: Mahmoud A Pouladi; Clinton S Robbins; Filip K Swirski; Meghan Cundall; Andrew N J McKenzie; Manel Jordana; Steven D Shapiro; Martin R Stämpfli
Interleukin-13-dependent expression of matrix metalloproteinase-12 is required for the development of airway eosinophilia in mice.
American journal of respiratory cell and molecular biology 2004;30(1):84-90.
2003: M I Aller; Alison Jones; Daniela Merlo; M Paterlini; Axel H Meyer; U Amtmann; Stephen G Brickley; Helen E Jolin; Andrew N J McKenzie; Hannah Monyer; Mark Farrant; william wisden
Cerebellar granule cell Cre recombinase expression.
Genesis (New York, N.Y. : 2000) 2003;36(2):97-103.
2003: Andrew N J McKenzie; Padraic G Fallon
Decoy receptors in the regulation of T helper cell type 2 responses.
The Journal of experimental medicine 2003;197(6):675-9.
2003: Christina A Herrick; Lan Xu; Andrew N J McKenzie; Robert E Tigelaar; Kim Bottomly
IL-13 is necessary, not simply sufficient, for epicutaneously induced Th2 responses to soluble protein antigen.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(5):2488-95.
2002: Stacey A Ritz; Meghan Cundall; Beata U Gajewska; David Alvarez; José-Carlos Gutierrez-Ramos; Anthony J Coyle; Andrew N J McKenzie; Martin R Stämpfli; Manel Jordana
Granulocyte macrophage colony-stimulating factor-driven respiratory mucosal sensitization induces Th2 differentiation and function independently of interleukin-4.
American journal of respiratory cell and molecular biology 2002;27(4):428-35.
2002: James Alexander; Frank Brombacher; H Adrienne McGachy; Andrew N J McKenzie; William Walker; Katharine C Carter
An essential role for IL-13 in maintaining a non-healing response following Leishmania mexicana infection.
European journal of immunology 2002;32(10):2923-33.
2002: Adam F Cunningham; Padraic G Fallon; Mahmood Khan; Sonia Vacheron; Hans Acha-Orbea; Ian C M MacLennan; Andrew N J McKenzie; Kai-Michael Toellner
Th2 activities induced during virgin T cell priming in the absence of IL-4, IL-13, and B cells.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(6):2900-6.
2002: Padraic G Fallon; Helen E Jolin; Philippa Smith; Claire L Emson; Michael J Townsend; Rosie E Fallon; Philip Smith; Andrew N J McKenzie
IL-4 induces characteristic Th2 responses even in the combined absence of IL-5, IL-9, and IL-13.
Immunity 2002;17(1):7-17.
2002: Rakesh K Kumar; Cristan Herbert; Ming Yang; Aulikki Koskinen; Andrew N J McKenzie; Paul S Foster
Role of interleukin-13 in eosinophil accumulation and airway remodelling in a mouse model of chronic asthma.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2002;32(7):1104-11.
2002: Joerg Mattes; Ming Yang; Surendran Mahalingam; Joachim Kuehr; Dianne C Webb; Ljubov Simson; Simon P Hogan; Aulikki Koskinen; Andrew N J McKenzie; Linday Agin Dent; Marc E Rothenberg; Klaus I Matthaei; Ian G Young; Paul S Foster
Intrinsic defect in T cell production of interleukin (IL)-13 in the absence of both IL-5 and eotaxin precludes the development of eosinophilia and airways hyperreactivity in experimental asthma.
The Journal of experimental medicine 2002;195(11):1433-44.
2002: Hal E Broxmeyer; Heather A Bruns; Shangming Zhang; Scott Cooper; Giao Hangoc; Andrew N J McKenzie; Alexander L Dent; Ulrike Schindler; Lisa K Naeger; Timothy Hoey; Mark H Kaplan
Th1 cells regulate hematopoietic progenitor cell homeostasis by production of oncostatin M.
Immunity 2002;16(6):815-25.
2002: Rakesh K Kumar; Paul S Thomas; Da-Qiang Seetoo; Cristan Herbert; Andrew N J McKenzie; Paul S Foster; Andrew R Lloyd
Eotaxin expression by epithelial cells and plasma cells in chronic asthma.
Laboratory investigation; a journal of technical methods and pathology 2002;82(4):495-504.
2002: Masaki Okamoto; Seiya Kato; Kotaro Oizumi; Masaharu Kinoshita; Yoshimasa Inoue; Katsuaki Hoshino; Shizuo Akira; Andrew N J McKenzie; Howard A Young; Tomoaki Hoshino
Interleukin 18 (IL-18) in synergy with IL-2 induces lethal lung injury in mice: a potential role for cytokines, chemokines, and natural killer cells in the pathogenesis of interstitial pneumonia.
Blood 2002;99(4):1289-98.
2002: Angus Lauder; Andrew N J McKenzie
Measurement of interleukin-13.
Current protocols in immunology / edited by John E. Coligan ... [et al.] 2002;Chapter 6():Unit 6.18.
2002: Sarah J McMillan; Benjamin Bishop; Michael J Townsend; Andrew N J McKenzie; Clare M Lloyd
The absence of interleukin 9 does not affect the development of allergen-induced pulmonary inflammation nor airway hyperreactivity.
The Journal of experimental medicine 2002;195(1):51-7.
2001: Dianne C Webb; Andrew N J McKenzie; Paul S Foster
Expression of the Ym2 lectin-binding protein is dependent on interleukin (IL)-4 and IL-13 signal transduction: identification of a novel allergy-associated protein.
The Journal of biological chemistry 2001;276(45):41969-76.
2001: DM Walter; Jennifer J McIntire; Gerald Berry; Andrew N J McKenzie; Debra D Donaldson; Rosemarie H Dekruyff; Dale T Umetsu
Critical role for IL-13 in the development of allergen-induced airway hyperreactivity.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(8):4668-75.
2001: Ming Yang; Simon P Hogan; Peter J Henry; Klaus I Matthaei; Andrew N J McKenzie; Ian G Young; Marc E Rothenberg; Paul S Foster
Interleukin-13 mediates airways hyperreactivity through the IL-4 receptor-alpha chain and STAT-6 independently of IL-5 and eotaxin.
American journal of respiratory cell and molecular biology 2001;25(4):522-30.
2001: Joerg Mattes; Ming Yang; A Siqueira; K Clark; J MacKenzie; Andrew N J McKenzie; Dianne C Webb; Klaus I Matthaei; Paul S Foster
IL-13 induces airways hyperreactivity independently of the IL-4R alpha chain in the allergic lung.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(3):1683-92.
2001: Liying Guo; Jane Hu-Li; Jinfang Zhu; Christophe Pannetier; C Watson; GJ McKenzie; Andrew N J McKenzie; William Paul
Disrupting Il13 impairs production of IL-4 specified by the linked allele.
Nature immunology 2001;2(5):461-6.
2001: Dianne C Webb; Andrew N J McKenzie; Klaus I Matthaei; Marc E Rothenberg; Paul S Foster
Distinct spatial requirement for eosinophil-induced airways hyperreactivity.
Immunology and cell biology 2001;79(2):165-9.
2001: Padraic G Fallon; Claire L Emson; Philip Smith; Andrew N J McKenzie
IL-13 overexpression predisposes to anaphylaxis following antigen sensitization.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(4):2712-6.
2001: Paul S Foster; AW Mould; Ming Yang; J Mackenzie; Joerg Mattes; Simon P Hogan; Surendran Mahalingam; Andrew N J McKenzie; Marc E Rothenberg; Ian G Young; Klaus I Matthaei; Dianne C Webb
Elemental signals regulating eosinophil accumulation in the lung.
Immunological reviews 2001;179():173-81.
2000: Andrew N J McKenzie
Regulation of T helper type 2 cell immunity by interleukin-4 and interleukin-13.
Pharmacology & therapeutics 2000;88(2):143-51.
2000: Dianne C Webb; Andrew N J McKenzie; Aulikki Koskinen; Ming Yang; Joerg Mattes; Paul S Foster
Integrated signals between IL-13, IL-4, and IL-5 regulate airways hyperreactivity.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(1):108-13.
2000: Michael J Townsend; Padraic G Fallon; D J Matthews; Helen E Jolin; Andrew N J McKenzie
T1/ST2-deficient mice demonstrate the importance of T1/ST2 in developing primary T helper cell type 2 responses.
The Journal of experimental medicine 2000;191(6):1069-76.
2000: Padraic G Fallon; Emma J Richardson; GJ McKenzie; Andrew N J McKenzie
Schistosome infection of transgenic mice defines distinct and contrasting pathogenic roles for IL-4 and IL-13: IL-13 is a profibrotic agent.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(5):2585-91.
2000: D J Matthews; Claire L Emson; GJ McKenzie; Helen E Jolin; J M Blackwell; Andrew N J McKenzie
IL-13 is a susceptibility factor for Leishmania major infection.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(3):1458-62.
1999: GJ McKenzie; Padraic G Fallon; Claire L Emson; Richard K Grencis; Andrew N J McKenzie
Simultaneous disruption of interleukin (IL)-4 and IL-13 defines individual roles in T helper cell type 2-mediated responses.
The Journal of experimental medicine 1999;189(10):1565-72.
1998: GJ McKenzie; Claire L Emson; S E Bell; S Anderson; Padraic G Fallon; G Zurawski; R Murray; Richard K Grencis; Andrew N J McKenzie
Impaired development of Th2 cells in IL-13-deficient mice.
Immunity 1998;9(3):423-32.
1998: Claire L Emson; S E Bell; Alison Jones; william wisden; Andrew N J McKenzie
Interleukin (IL)-4-independent induction of immunoglobulin (Ig)E, and perturbation of T cell development in transgenic mice expressing IL-13.
The Journal of experimental medicine 1998;188(2):399-404.
1998: Allison J Bancroft; Andrew N J McKenzie; Richard K Grencis
A critical role for IL-13 in resistance to intestinal nematode infection.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(7):3453-61.
1998: GJ McKenzie; Allison J Bancroft; Richard K Grencis; Andrew N J McKenzie
A distinct role for interleukin-13 in Th2-cell-mediated immune responses.
Current biology : CB 1998;8(6):339-42.
1996: J Corral; Isabelle Lavenir; H Impey; Amy J Warren; Alan Forster; T A Larson; S Bell; Andrew N J McKenzie; G King; Terence H Rabbitts
An Mll-AF9 fusion gene made by homologous recombination causes acute leukemia in chimeric mice: a method to create fusion oncogenes.
Cell 1996;85(6):853-61.
1995: Sandra Zurawski; P Chomarat; O Djossou; C Bidaud; Andrew N J McKenzie; Pierre Miossec; Jacques Banchereau; Gerard Zurawski
The primary binding subunit of the human interleukin-4 receptor is also a component of the interleukin-13 receptor.
The Journal of biological chemistry 1995;270(23):13869-78.
1995: Andrew N J McKenzie; Gerard Zurawski
Interleukin-13: characterization and biologic properties.
Cancer treatment and research 1995;80():367-78.
1993: Andrew N J McKenzie; X Li; David Largaespada; A Sato; A Kaneda; Sandra Zurawski; E L Doyle; A Milatovich; U Francke; N G Copeland
Structural comparison and chromosomal localization of the human and mouse IL-13 genes.
Journal of immunology (Baltimore, Md. : 1950) 1993;150(12):5436-44.
1993: Andrew N J McKenzie; J A Culpepper; Rene de Waal Malefyt; F Brière; J Punnonen; Gregorio Aversa; A Sato; W Dang; BG Cocks; Satish Menon
Interleukin 13, a T-cell-derived cytokine that regulates human monocyte and B-cell function.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(8):3735-9.
1993: J Punnonen; Gregorio Aversa; BG Cocks; Andrew N J McKenzie; Satish Menon; Gerard Zurawski; Rene de Waal Malefyt; Jan E de Vries
Interleukin 13 induces interleukin 4-independent IgG4 and IgE synthesis and CD23 expression by human B cells.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(8):3730-4.