Preview
Sign-in for full Details 
Sign-in free and Explore the Exciting World of BiomedExperts:
- Over 1.500.000 Profiles
- More than 1.800 Organizations worldwide
- State of the Art Network Visualizations
- Manage your own Profile
- Locate Experts in your Country/Region
- Locate Experts in your 1. and 2. Level Network
- Connect to Experts Worldwide
NetworkView
John McKew
This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers
together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles
free of charge to researchers worldwide.
Research Profile (preview)
Chemicals & Drugs
Concepts & Ideas
Living Beings
Genes & Molecular Sequences
Anatomy
Procedures
Disorders
Physiology
Sign-in to see full Profile
Network (preview)
9
Clark, James
7
Shen, Marina
7
Tam, Steve
6
Xu, Xin
5
Chen, Lihren
4
Zhang, Wen
3
Wang, Weiheng
3
Nickerson-Nutter, Cheryl
3
Ramarao, Manjunath
3
Kirincich, Steven
3
Lovering, Frank
2
Abraham, William
2
Ipek, Manus
2
Joseph-McCarthy, Diane
2
Khor, Soo Peang
Sign-in to see all Coauthors
Publications
Sign-in to see all Publications
Sign in free and see...
Visualized networks:
See your personal network in
sophisticated graphical views
GeoTargeted Searches:
Locate experts around the world
and connect with global collaborators
Research Profiles:
See the visualized research activity
of experts around the globe
Sign-in to see more
Geonetwork of John McKew (preview)
Cities where this author has publications
Cities where co-authors of this author have publications
Sign-in to see more
All Publications
-
2009: Kirincich Steven J; Xiang Jason; Green Neal; Tam Steve; Yang Hui Y; Shim Jaechul; Shen Marina W H; Clark James D; McKew John C
Benzhydrylquinazolinediones: novel cytosolic phospholipase A2alpha inhibitors with improved physicochemical properties.
Bioorganic & medicinal chemistry 2009;17(13):4383-405.
-
2009: Chen Lihren; Wang Weiheng; Lee Katherine L; Shen Marina W H; Murphy Elizabeth A; Zhang Wen; Xu Xin; Tam Steve; Nickerson-Nutter Cheryl; Goodwin Debra G; Clark James D; McKew John C
Reactions of functionalized sulfonamides: application to lowering the lipophilicity of cytosolic phospholipase A2alpha inhibitors.
Journal of medicinal chemistry 2009;52(4):1156-71.
-
2008: Marusic Suzana; Thakker Paresh; Pelker Jeffrey W; Stedman Nancy L; Lee Katherine L; McKew John C; Han Lixin; Xu Xin; Wolf Stan F; Borey Adam J; Cui Junqing; Shen Marina W H; Donahue Fran; Hassan-Zahraee Mina; Leach Michael W; Shimizu Takao; Clark James D
Blockade of cytosolic phospholipase A2 alpha prevents experimental autoimmune encephalomyelitis and diminishes development of Th1 and Th17 responses.
Journal of neuroimmunology 2008;204(1-2):29-37.
-
2008: Xiang Jason; Wan Zhao-Kui; Li Huan-Qiu; Ipek Manus; Binnun Eva; Nunez Jill; Chen Lihren; McKew John C; Mansour Tarek S; Xu Xin; Suri Vipin; Tam May; Xing Yuzhe; Li Xiangping; Hahm Seung; Tobin James; Saiah Eddine
Piperazine sulfonamides as potent, selective, and orally available 11beta-hydroxysteroid dehydrogenase type 1 inhibitors with efficacy in the rat cortisone-induced hyperinsulinemia model.
Journal of medicinal chemistry 2008;51(14):4068-71.
-
2008: McKew John C; Lee Katherine L; Shen Marina W H; Thakker Paresh; Foley Megan A; Behnke Mark L; Hu Baihua; Sum Fuk-Wah; Tam Steve; Hu Yonghan; Chen Lihren; Kirincich Steven J; Michalak Ronald; Thomason Jennifer; Ipek Manus; Wu Kun; Wooder Lane; Ramarao Manjunath K; Murphy Elizabeth A; Goodwin Debra G; Albert Leo; Xu Xin; Donahue Frances; Ku M Sherry; Keith James; Nickerson-Nutter Cheryl L; Abraham William M; Williams Cara; Hegen Martin; Clark James D
Indole cytosolic phospholipase A2 alpha inhibitors: discovery and in vitro and in vivo characterization of 4-{3-[5-chloro-2-(2-{[(3,4-dichlorobenzyl)sulfonyl]amino}ethyl)-1-(diphenylmethyl)-1H-indol-3-yl]propyl}benzoic acid, efipladib.
Journal of medicinal chemistry 2008;51(12):3388-413.
-
2008: Lee Katherine L; Behnke Mark L; Foley Megan A; Chen Lihren; Wang Weiheng; Vargas Richard; Nunez Jill; Tam Steve; Mollova Nevena; Xu Xin; Shen Marina W H; Ramarao Manjunath K; Goodwin Debra G; Nickerson-Nutter Cheryl L; Abraham William M; Williams Cara; Clark James D; McKew John C
Benzenesulfonamide indole inhibitors of cytosolic phospholipase A2alpha: optimization of in vitro potency and rat pharmacokinetics for oral efficacy.
Bioorganic & medicinal chemistry 2008;16(3):1345-58.
-
2007: Lee Katherine L; Foley Megan A; Chen Lihren; Behnke Mark L; Lovering Frank E; Kirincich Steven J; Wang Weiheng; Shim Jaechul; Tam Steve; Shen Marina W H; Khor Soopeang; Xu Xin; Goodwin Debra G; Ramarao Manjunath K; Nickerson-Nutter Cheryl; Donahue Frances; Ku M Sherry; Clark James D; McKew John C
Discovery of Ecopladib, an indole inhibitor of cytosolic phospholipase A2alpha.
Journal of medicinal chemistry 2007;50(6):1380-400.
-
2006: Gopalsamy Ariamala; Yang Hui; Ellingboe John W; McKew John C; Tam Steve; Joseph-McCarthy Diane; Zhang Wen; Shen Marina; Clark James D
1,2,4-Oxadiazolidin-3,5-diones and 1,3,5-triazin-2,4,6-triones as cytosolic phospholipase A2alpha inhibitors.
Bioorganic & medicinal chemistry letters 2006;16(11):2978-81.
-
2006: McKew John C; Foley Megan A; Thakker Paresh; Behnke Mark L; Lovering Frank E; Sum Fuk-Wah; Tam Steve; Wu Kun; Shen Marina W H; Zhang Wen; Gonzalez Mario; Liu Shanghao; Mahadevan Anu; Sard Howard; Khor Soo Peang; Clark James D
Inhibition of cytosolic phospholipase A2alpha: hit to lead optimization.
Journal of medicinal chemistry 2006;49(1):135-58.
-
2003: McKew John C; Lovering Frank; Clark James D; Bemis Jean; Xiang YiBin; Shen Marina; Zhang Wen; Alvarez Juan C; Joseph-McCarthy Diane
Structure-activity relationships of indole cytosolic phospholipase A(2)alpha inhibitors: substrate mimetics.
Bioorganic & medicinal chemistry letters 2003;13(24):4501-4.
Sign-in to see more
