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Webb McKnight

Research Profile

Living Beings

Chemicals & Drugs

Disorders

Stomach Ulcer

Anatomy

Physiology

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Publications

TOP 3
W Elsheikh; J G P Ferraz; K L Flannigan; Webb McKnight; J L Wallace
Dextran sulfate sodium induces pan-gastroenteritis in rodents: implications for studies of colitis.
John L Wallace; Stephanie Syer; Elena F Verdu; Linda Vong; Premysl Bercik; Manlio Bolla; Stephen M Collins; Giada de Palma; emmanuel denou; Jennifer Jury; Webb McKnight; Ennio Ongini
Proton pump inhibitors exacerbate NSAID-induced small intestinal injury by inducing dysbiosis.
John L Wallace; Linda Vong; Webb McKnight; Michael Dicay; Gary R Martin
Endogenous and exogenous hydrogen sulfide promotes resolution of colitis in rats.

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All Publications

2012: W Elsheikh; J G P Ferraz; K L Flannigan; Webb McKnight; J L Wallace
Dextran sulfate sodium induces pan-gastroenteritis in rodents: implications for studies of colitis.
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 2012;63(5):463-9.
2011: John L Wallace; Stephanie Syer; Elena F Verdu; Linda Vong; Premysl Bercik; Manlio Bolla; Stephen M Collins; Giada de Palma; emmanuel denou; Jennifer Jury; Webb McKnight; Ennio Ongini
Proton pump inhibitors exacerbate NSAID-induced small intestinal injury by inducing dysbiosis.
Gastroenterology 2011;141(4):1314-22, 1322.e1-5.
2009: John L Wallace; Linda Vong; Webb McKnight; Michael Dicay; Gary R Martin
Endogenous and exogenous hydrogen sulfide promotes resolution of colitis in rats.
Gastroenterology 2009;137(2):569-78, 578.e1.
2008: A E Chávez-Piña; L Vong; Webb McKnight; Michael Dicay; Renata C O Zanardo; M I Ortiz; G Castañeda-Hernández; John L Wallace
Lack of effects of acemetacin on signalling pathways for leukocyte adherence may explain its gastrointestinal safety.
British journal of pharmacology 2008;155(6):857-64.
2007: John L Wallace; Michael Dicay; Webb McKnight; Gary R Martin
Hydrogen sulfide enhances ulcer healing in rats.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2007;21(14):4070-6.
2007: A E Chávez-Piña; Webb McKnight; Michael Dicay; G Castañeda-Hernández; John L Wallace
Mechanisms underlying the anti-inflammatory activity and gastric safety of acemetacin.
British journal of pharmacology 2007;152(6):930-8.
2006: John L Wallace; Michael Dicay; Webb McKnight; Genevieve K Dudar
Platelets accelerate gastric ulcer healing through presentation of vascular endothelial growth factor.
British journal of pharmacology 2006;148(3):274-8.
2005: Li Ma; Rafael Perini; Webb McKnight; Michael Dicay; André Klein; Morley D Hollenberg; John L Wallace
Proteinase-activated receptors 1 and 4 counter-regulate endostatin and VEGF release from human platelets.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(1):216-20.
2004: John L Wallace; Stella R Zamuner; Webb McKnight; Michael Dicay; Andrea Mencarelli; Piero Del Soldato; Stefano Fiorucci
Aspirin, but not NO-releasing aspirin (NCX-4016), interacts with selective COX-2 inhibitors to aggravate gastric damage and inflammation.
American journal of physiology. Gastrointestinal and liver physiology 2004;286(1):G76-81.
2002: Stefano Fiorucci; Octavio Menezes de Lima; Andrea Mencarelli; Barbara Palazzetti; Eleonora Distrutti; Webb McKnight; Michael Dicay; Li Ma; Mario Romano; Antonio Morelli; John L Wallace
Cyclooxygenase-2-derived lipoxin A4 increases gastric resistance to aspirin-induced damage.
Gastroenterology 2002;123(5):1598-606.
2001: M J Miller; Nathalie Vergnolle; Webb McKnight; R A Musah; C A Davison; AM Trentacosti; JH Thompson; M Sandoval; J L Wallace
Inhibition of neurogenic inflammation by the Amazonian herbal medicine sangre de grado.
The Journal of investigative dermatology 2001;117(3):725-30.
2001: Marcelo N Muscará; Fina Lovren; Webb McKnight; Michael Dicay; Piero Del Soldato; Chris R Triggle; John L Wallace
Vasorelaxant effects of a nitric oxide-releasing aspirin derivative in normotensive and hypertensive rats.
British journal of pharmacology 2001;133(8):1314-22.
2000: K Barnett; C J Bell; Webb McKnight; Michael Dicay; Keith Sharkey; John L Wallace
Role of cyclooxygenase-2 in modulating gastric acid secretion in the normal and inflamed rat stomach.
American journal of physiology. Gastrointestinal and liver physiology 2000;279(6):G1292-7.
2000: John L Wallace; Webb McKnight; BK Reuter; Nathalie Vergnolle
NSAID-induced gastric damage in rats: requirement for inhibition of both cyclooxygenase 1 and 2.
Gastroenterology 2000;119(3):706-14.
2000: Marcelo N Muscará; Webb McKnight; Fina Lovren; Chris R Triggle; Giuseppe Cirino; John L Wallace
Antihypertensive properties of a nitric oxide-releasing naproxen derivative in two-kidney, one-clip rats.
American journal of physiology. Heart and circulatory physiology 2000;279(2):H528-35.
2000: Marcelo N Muscará; Webb McKnight; Samuel Asfaha; John L Wallace
Wound collagen deposition in rats: effects of an NO-NSAID and a selective COX-2 inhibitor.
British journal of pharmacology 2000;129(4):681-6.
2000: SN Elliott; John L Wallace; Webb McKnight; D Grant Gall; James A Hardin; M Olson; Andre G Buret
Bacterial colonization and healing of gastric ulcers: the effects of epidermal growth factor.
American journal of physiology. Gastrointestinal and liver physiology 2000;278(1):G105-12.
1999: John L Wallace; Michael Dicay; Webb McKnight; S Bastaki; M A Blank
N-bisphosphonates cause gastric epithelial injury independent of effects on the microcirculation.
Alimentary pharmacology & therapeutics 1999;13(12):1675-82.
1999: John L Wallace; Nathalie Vergnolle; Marcelo N Muscará; Samuel Asfaha; Kevin Chapman; Webb McKnight; Piero Del Soldato; A Morelli; Stefano Fiorucci
Enhanced anti-inflammatory effects of a nitric oxide-releasing derivative of mesalamine in rats.
Gastroenterology 1999;117(3):557-66.
1999: John L Wallace; Kevin Chapman; Webb McKnight
Limited anti-inflammatory efficacy of cyclo-oxygenase-2 inhibition in carrageenan-airpouch inflammation.
British journal of pharmacology 1999;126(5):1200-4.
1999: John L Wallace; Marcelo N Muscara; Webb McKnight; Michael Dicay; Piero Del Soldato; G Cirino
In vivo antithrombotic effects of a nitric oxide-releasing aspirin derivative, NCX-4016.
Thrombosis research 1999;93(1):43-50.
1998: SN Elliott; Andre G Buret; Webb McKnight; M J Miller; John L Wallace
Bacteria rapidly colonize and modulate healing of gastric ulcers in rats.
The American journal of physiology 1998;275(3 Pt 1):G425-32.
1998: John L Wallace; AW Bak; Webb McKnight; Samuel Asfaha; Keith Sharkey; Wallace K MacNaughton
Cyclooxygenase 1 contributes to inflammatory responses in rats and mice: implications for gastrointestinal toxicity.
Gastroenterology 1998;115(1):101-9.
1998: John L Wallace; Webb McKnight; Samuel Asfaha; D Y Liu
Reduction of acute and reactivated colitis in rats by an inhibitor of neutrophil activation.
The American journal of physiology 1998;274(5 Pt 1):G802-8.
1998: John L Wallace; BK Reuter; Webb McKnight; AW Bak
Selective inhibitors of cyclooxygenase-2: are they really effective, selective, and GI-safe?
Journal of clinical gastroenterology 1998;27 Suppl 1():S28-34.
1998: AW Bak; Webb McKnight; P Li; Piero Del Soldato; A Calignano; Giuseppe Cirino; John L Wallace
Cyclooxygenase-independent chemoprevention with an aspirin derivative in a rat model of colonic adenocarcinoma.
Life sciences 1998;62(23):PL 367-73.
1998: Marcelo N Muscará; Webb McKnight; Piero Del Soldato; John L Wallace
Effect of a nitric oxide-releasing naproxen derivative on hypertension and gastric damage induced by chronic nitric oxide inhibition in the rat.
Life sciences 1998;62(15):PL235-40.
1998: SN Elliott; Webb McKnight; N M Davies; Wallace K MacNaughton; John L Wallace
Alendronate induces gastric injury and delays ulcer healing in rodents.
Life sciences 1998;62(1):77-91.
1997: John L Wallace; Webb McKnight; Tammy L Wilson; Piero Del Soldato; Giuseppe Cirino
Reduction of shock-induced gastric damage by a nitric oxide-releasing aspirin derivative: role of neutrophils.
The American journal of physiology 1997;273(6 Pt 1):G1246-51.
1997: J G Ferraz; Keith Sharkey; BK Reuter; Samuel Asfaha; AW Tigley; M L Brown; Webb McKnight; John L Wallace
Induction of cyclooxygenase 1 and 2 in the rat stomach during endotoxemia: role in resistance to damage.
Gastroenterology 1997;113(1):195-204.
1997: Neal M Davies; A G Røseth; CB Appleyard; Webb McKnight; Piero Del Soldato; A Calignano; Giuseppe Cirino; John L Wallace
NO-naproxen vs. naproxen: ulcerogenic, analgesic and anti-inflammatory effects.
Alimentary pharmacology & therapeutics 1997;11(1):69-79.
1995: John L Wallace; Webb McKnight; Piero Del Soldato; A R Baydoun; Giuseppe Cirino
Anti-thrombotic effects of a nitric oxide-releasing, gastric-sparing aspirin derivative.
The Journal of clinical investigation 1995;96(6):2711-8.
1995: SN Elliott; Webb McKnight; Giuseppe Cirino; John L Wallace
A nitric oxide-releasing nonsteroidal anti-inflammatory drug accelerates gastric ulcer healing in rats.
Gastroenterology 1995;109(2):524-30.
1995: J G Ferraz; Webb McKnight; Keith Sharkey; John L Wallace
Impaired vasodilatory responses in the gastric microcirculation of anesthetized rats with secondary biliary cirrhosis.
Gastroenterology 1995;108(4):1183-91.
1994: John L Wallace; L Carter; Webb McKnight; Susanne Tries; Stefan Laufer
ML 3000 reduces gastric prostaglandin synthesis without causing mucosal injury.
European journal of pharmacology 1994;271(2-3):525-31.
1994: John L Wallace; BK Reuter; Carla Cicala; Webb McKnight; M B Grisham; Giuseppe Cirino
Novel nonsteroidal anti-inflammatory drug derivatives with markedly reduced ulcerogenic properties in the rat.
Gastroenterology 1994;107(1):173-9.
1994: John L Wallace; BK Reuter; Carla Cicala; Webb McKnight; M Grisham; Giuseppe Cirino
A diclofenac derivative without ulcerogenic properties.
European journal of pharmacology 1994;257(3):249-55.
1993: John L Wallace; Donna-Marie McCafferty; L Carter; Webb McKnight; Dennis Argentieri
Tissue-selective inhibition of prostaglandin synthesis in rat by tepoxalin: anti-inflammatory without gastropathy?
Gastroenterology 1993;105(6):1630-6.
1993: John L Wallace; Webb McKnight; M Miyasaka; T Tamatani; J Paulson; D C Anderson; DN Granger; Paul Kubes
Role of endothelial adhesion molecules in NSAID-induced gastric mucosal injury.
The American journal of physiology 1993;265(5 Pt 1):G993-8.
1993: P L Beck; Webb McKnight; Samuel S Lee; John L Wallace
Prostaglandin modulation of the gastric vasculature and mucosal integrity in cirrhotic rats.
The American journal of physiology 1993;265(3 Pt 1):G453-8.
1992: John L Wallace; K P Rioux; Webb McKnight; L Carter; D Jourd'heuil; Jonathan B Meddings; B J Zimmerman; DN Granger; M B Grisham
Hemoprotein-dependent production of a neutrophil-activating factor from arachidonic acid.
The American journal of physiology 1992;263(5 Pt 2):H1546-53.
1989: John L Wallace; Giuseppe Cirino; G De Nucci; Webb McKnight; Wallace K MacNaughton
Endothelin has potent ulcerogenic and vasoconstrictor actions in the stomach.
The American journal of physiology 1989;256(4 Pt 1):G661-6.