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Diane McMahon-Pratt

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Dawn M Wetzel; Diane McMahon-Pratt; Anthony J Koleske
The Abl and Arg kinases mediate distinct modes of phagocytosis and are required for maximal Leishmania infection.
Carolina Ramírez; Ricardo Rojas; Nancy G Saravia; Jair Tellez; Irina Tikhonova; Liliana Valderrama; Mary E Wilson; Hongyu Zhao; Neal D Alexander; Tiago M Castilho; Yira Díaz-Toro; Nicholas A Ettinger; Janet Hager; Aiping Lin; Diane McMahon-Pratt
Human macrophage response to L. (Viannia) panamensis: microarray evidence for an early inflammatory response.
Asha Jayakumar; Jenefer M Blackwell; Tiago M Castilho; Karen Goldsmith-Pestana; Esther Park; Diane McMahon-Pratt
TLR1/2 activation during heterologous prime-boost vaccination (DNA-MVA) enhances CD8+ T Cell responses providing protection against Leishmania (Viannia).

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All Publications

2012: Dawn M Wetzel; Diane McMahon-Pratt; Anthony J Koleske
The Abl and Arg kinases mediate distinct modes of phagocytosis and are required for maximal Leishmania infection.
Molecular and cellular biology 2012;32(15):3176-86.
2012: Carolina Ramírez; Ricardo Rojas; Nancy G Saravia; Jair Tellez; Irina Tikhonova; Liliana Valderrama; Mary E Wilson; Hongyu Zhao; Neal D Alexander; Tiago M Castilho; Yira Díaz-Toro; Nicholas A Ettinger; Janet Hager; Aiping Lin; Diane McMahon-Pratt
Human macrophage response to L. (Viannia) panamensis: microarray evidence for an early inflammatory response.
PLoS neglected tropical diseases 2012;6(10):e1866.
2011: Asha Jayakumar; Jenefer M Blackwell; Tiago M Castilho; Karen Goldsmith-Pestana; Esther Park; Diane McMahon-Pratt
TLR1/2 activation during heterologous prime-boost vaccination (DNA-MVA) enhances CD8+ T Cell responses providing protection against Leishmania (Viannia).
PLoS neglected tropical diseases 2011;5(6):e1204.
2010: Tiago M Castilho; Karen Goldsmith-Pestana; Caterin Lozano; Liliana Valderrama; Nancy G Saravia; Diane McMahon-Pratt
Murine model of chronic L. (Viannia) panamensis infection: role of IL-13 in disease.
European journal of immunology 2010;40(10):2816-29.
2010: Eszter Deak; Asha Jayakumar; Ka Wing Cho; Karen Goldsmith-Pestana; Blaise Dondji; John D Lambris; Diane McMahon-Pratt
Murine visceral leishmaniasis: IgM and polyclonal B-cell activation lead to disease exacerbation.
European journal of immunology 2010;40(5):1355-68.
2008: Daniela Kamir; Swen Zierow; Lin Leng; Yoonsang Cho; Yira Diaz; Jason Griffith; Courtney McDonald; Melanie Merk; Robert A Mitchell; John Trent; Yibang Chen; Yuen-Kwan Amy Kwong; Huabao Xiong; Jon Vermeire; Michael Cappello; Diane McMahon-Pratt; John Walker; Jürgen Bernhagen; Elias Lolis; Richard Bucala
A Leishmania ortholog of macrophage migration inhibitory factor modulates host macrophage responses.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(12):8250-61.
2008: Blaise Dondji; Richard D Bungiro; Lisa M Harrison; Jon J Vermeire; Carlo Bifulco; Diane McMahon-Pratt; Michael Cappello
Role for nitric oxide in hookworm-associated immune suppression.
Infection and immunity 2008;76(6):2560-7.
2008: Shanta M Whitaker; María Colmenares; Karen Goldsmith Pestana; Diane McMahon-Pratt
Leishmania pifanoi proteoglycolipid complex P8 induces macrophage cytokine production through Toll-like receptor 4.
Infection and immunity 2008;76(5):2149-56.
2008: Blaise Dondji; Eszter Deak; Karen Goldsmith-Pestana; Eva Perez-Jimenez; Mariano Esteban; Sachiko Miyake; Takashi Yamamura; Diane McMahon-Pratt
Intradermal NKT cell activation during DNA priming in heterologous prime-boost vaccination enhances T cell responses and protection against Leishmania.
European journal of immunology 2008;38(3):706-19.
2008: Didi Matza; Abdallah Badou; Koichi Kobayashi; Karen Goldsmith-Pestana; Yutaka Masuda; Akihiko Komuro; Diane McMahon-Pratt; Vincent T Marchesi; Richard A Flavell
A scaffold protein, AHNAK1, is required for calcium signaling during T cell activation.
Immunity 2008;28(1):64-74.
2008: Tiago Moreno Castilho; Luis Marcelo A Camargo; Diane McMahon-Pratt; Jeffrey J Shaw; Lucile Maria Floeter-Winter
A real-time polymerase chain reaction assay for the identification and quantification of American Leishmania species on the basis of glucose-6-phosphate dehydrogenase.
The American journal of tropical medicine and hygiene 2008;78(1):122-32.
2007: E Carrillo; S Ahmed; Karen Goldsmith-Pestana; J Nieto; Elvia osorio; bruno travi; J Moreno; Diane McMahon-Pratt
Immunogenicity of the P-8 amastigote antigen in the experimental model of canine visceral leishmaniasis.
Vaccine 2007;25(8):1534-43.
2005: Blaise Dondji; Eva Pérez-Jimenez; Karen Goldsmith-Pestana; Mariano Esteban; Diane McMahon-Pratt
Heterologous prime-boost vaccination with the LACK antigen protects against murine visceral leishmaniasis.
Infection and immunity 2005;73(8):5286-9.
2005: Sujata Kar; Christine Metz; Diane McMahon-Pratt
CD4+ T cells play a dominant role in protection against New World leishmaniasis induced by vaccination with the P-4 amastigote antigen.
Infection and immunity 2005;73(6):3823-7.
2004: Diane McMahon-Pratt; James Alexander
Does the Leishmania major paradigm of pathogenesis and protection hold for New World cutaneous leishmaniases or the visceral disease?
Immunological reviews 2004;201():206-24.
2004: Susanne Nylén; K Maasho; Diane McMahon-Pratt; Hannah Akuffo
Leishmanial amastigote antigen P-2 induces major histocompatibility complex class II-dependent natural killer-cell reactivity in cells from healthy donors.
Scandinavian journal of immunology 2004;59(3):294-304.
2003: María Colmenares; Peter E Kima; Erika Samoff; Lynn Soong; Diane McMahon-Pratt
Perforin and gamma interferon are critical CD8+ T-cell-mediated responses in vaccine-induced immunity against Leishmania amazonensis infection.
Infection and immunity 2003;71(6):3172-82.
2003: K Maasho; Diane McMahon-Pratt; J Raita; M Raud; Sven Britton; Lynn Soong; Hannah Akuffo
Evaluation of amastigote reactive cells in human cutaneous leishmaniasis caused by Leishmania aethiopica.
Clinical and experimental immunology 2003;132(2):316-22.
2003: Saeed Ahmed; María Colmenares; Lynn Soong; Karen Goldsmith-Pestana; Leonard E Munstermann; R Molina; Diane McMahon-Pratt
Intradermal infection model for pathogenesis and vaccine studies of murine visceral leishmaniasis.
Infection and immunity 2003;71(1):401-10.
2002: María Colmenares; Stephanie L Constant; Peter E Kima; Diane McMahon-Pratt
Leishmania pifanoi pathogenesis: selective lack of a local cutaneous response in the absence of circulating antibody.
Infection and immunity 2002;70(12):6597-605.
2002: Nancy G Saravia; Kristen A Weigle; Claudia Navas; Iris Segura; Liliana Valderrama; Anais Zully Valencia; Blanca Escorcia; Diane McMahon-Pratt
Heterogeneity, geographic distribution, and pathogenicity of serodemes of Leishmania viannia in Colombia.
The American journal of tropical medicine and hygiene 2002;66(6):738-44.
2002: María Colmenares; Sujata Kar; Karen Goldsmith-Pestana; Diane McMahon-Pratt
Mechanisms of pathogenesis: differences amongst Leishmania species.
Transactions of the Royal Society of Tropical Medicine and Hygiene 2002;96 Suppl 1():S3-7.
2001: María Colmenares; Michael Tiemeyer; Peter E Kima; Diane McMahon-Pratt
Biochemical and biological characterization of the protective Leishmania pifanoi amastigote antigen P-8.
Infection and immunity 2001;69(11):6776-84.
2000: Sujata Kar; Lynn Soong; María Colmenares; Karen Goldsmith-Pestana; Diane McMahon-Pratt
The immunologically protective P-4 antigen of Leishmania amastigotes. A developmentally regulated single strand-specific nuclease associated with the endoplasmic reticulum.
The Journal of biological chemistry 2000;275(48):37789-97.
2000: Peter E Kima; Stephanie L Constant; Lynn G Hannum; María Colmenares; K S Lee; Ann M Haberman; Mark J Shlomchik; Diane McMahon-Pratt
Internalization of Leishmania mexicana complex amastigotes via the Fc receptor is required to sustain infection in murine cutaneous leishmaniasis.
The Journal of experimental medicine 2000;191(6):1063-8.
1998: J E Haberer; Alda Maria Da-Cruz; Lynn Soong; Manoel Paes Oliveira-Neto; L Rivas; Diane McMahon-Pratt; Sergio G Coutinho
Leishmania pifanoi amastigote antigen P-4: epitopes involved in T-cell responsiveness in human cutaneous leishmaniasis.
Infection and immunity 1998;66(7):3100-5.
1998: Diane McMahon-Pratt; Peter E Kima; Lynn Soong
Leishmania amastigote target antigens: the challenge of a stealthy intracellular parasite.
Parasitology today (Personal ed.) 1998;14(1):31-4.
1998: Fernando T Silveira; Jenefer M Blackwell; E A Y Ishikawa; R Braga; Jeffrey J Shaw; Rupert J Quinnell; Lynn Soong; Peter E Kima; Diane McMahon-Pratt; Gillian F Black; Marie-Anne Shaw
T cell responses to crude and defined leishmanial antigens in patients from the lower Amazon region of Brazil infected with different species of Leishmania of the subgenera Leishmania and Viannia.
Parasite immunology 1998;20(1):19-26.
1997: Peter E Kima; Nancy H Ruddle; Diane McMahon-Pratt
Presentation via the class I pathway by Leishmania amazonensis-infected macrophages of an endogenous leishmanial antigen to CD8+ T cells.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(4):1828-34.
1997: Lynn Soong; Cheong-Hee Chang; J Sun; B Jack Longley; Nancy H Ruddle; Richard A Flavell; Diane McMahon-Pratt
Role of CD4+ T cells in pathogenesis associated with Leishmania amazonensis infection.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(11):5374-83.
1996: Peter E Kima; Lynn Soong; C Chicharro; Nancy H Ruddle; Diane McMahon-Pratt
Leishmania-infected macrophages sequester endogenously synthesized parasite antigens from presentation to CD4+ T cells.
European journal of immunology 1996;26(12):3163-9.
1996: Sergio G Coutinho; Oliveira Marcia; Alda Maria Da-Cruz; Paula Melo De Luca; S C Mendonça; Alvaro Luiz Bertho; Lynn Soong; Diane McMahon-Pratt
T-cell responsiveness of American cutaneous leishmaniasis patients to purified Leishmania pifanoi amastigote antigens and Leishmania braziliensis promastigote antigens: immunologic patterns associated with cure.
Experimental parasitology 1996;84(2):144-55.
1996: V H Hodgkinson; Lynn Soong; S M Duboise; Diane McMahon-Pratt
Leishmania amazonensis: cultivation and characterization of axenic amastigote-like organisms.
Experimental parasitology 1996;83(1):94-105.
1996: Lynn Soong; J C Xu; Iqbal Grewal; Peter E Kima; J Sun; B J Longley; Nancy H Ruddle; Diane McMahon-Pratt; Richard A Flavell
Disruption of CD40-CD40 ligand interactions results in an enhanced susceptibility to Leishmania amazonensis infection.
Immunity 1996;4(3):263-73.
1996: Gabriel Grimaldi; Diane McMahon-Pratt
Monoclonal antibodies for the identification of New World Leishmania species.
Memórias do Instituto Oswaldo Cruz 1996;91(1):37-42.
1996: V F Amaral; V A Ransatto; F Conceicão-Silva; E Molinaro; V Ferreira; Sergio G Coutinho; Diane McMahon-Pratt; Gabriel Grimaldi
Leishmania amazonensis: the Asian rhesus macaques (Macaca mulatta) as an experimental model for study of cutaneous leishmaniasis.
Experimental parasitology 1996;82(1):34-44.
1995: Antonio Campos-Neto; Lynn Soong; J L Cordova; Derek B Sant'Angelo; Yasir A W Skeiky; Nancy H Ruddle; Steven G Reed; C Janeway; Diane McMahon-Pratt
Cloning and expression of a Leishmania donovani gene instructed by a peptide isolated from major histocompatibility complex class II molecules of infected macrophages.
The Journal of experimental medicine 1995;182(5):1423-33.
1995: Lynn Soong; S M Duboise; Peter E Kima; Diane McMahon-Pratt
Leishmania pifanoi amastigote antigens protect mice against cutaneous leishmaniasis.
Infection and immunity 1995;63(9):3559-66.
1994: S M Duboise; M A Vannier-Santos; D Costa-Pinto; L Rivas; Alfred A Pan; Y Traub-Cseko; W De Souza; Diane McMahon-Pratt
The biosynthesis, processing, and immunolocalization of Leishmania pifanoi amastigote cysteine proteinases.
Molecular and biochemical parasitology 1994;68(1):119-32.
1993: Diane McMahon-Pratt; D Rodriguez; J R Rodriguez; Y Zhang; K Manson; C Bergman; L Rivas; J F Rodriguez; K L Lohman; Nancy H Ruddle
Recombinant vaccinia viruses expressing GP46/M-2 protect against Leishmania infection.
Infection and immunity 1993;61(8):3351-9.
1993: Alfred A Pan; S M Duboise; S Eperon; L Rivas; V Hodgkinson; Y Traub-Cseko; Diane McMahon-Pratt
Developmental life cycle of Leishmania--cultivation and characterization of cultured extracellular amastigotes.
The Journal of eukaryotic microbiology 1993;40(2):213-23.
1993: Y M Traub-Cseko; M Duboise; L K Boukai; Diane McMahon-Pratt
Identification of two distinct cysteine proteinase genes of Leishmania pifanoi axenic amastigotes using the polymerase chain reaction.
Molecular and biochemical parasitology 1993;57(1):101-15.
1992: Diane McMahon-Pratt; Y Traub-Cseko; K L Lohman; D D Rogers; S M Beverley
Loss of the GP46/M-2 surface membrane glycoprotein gene family in the Leishmania braziliensis complex.
Molecular and biochemical parasitology 1992;50(1):151-60.
1991: P M Rainey; T W Spithill; Diane McMahon-Pratt; Alfred A Pan
Biochemical and molecular characterization of Leishmania pifanoi amastigotes in continuous axenic culture.
Molecular and biochemical parasitology 1991;49(1):111-8.
1991: L Rivas; L Kahl; K Manson; Diane McMahon-Pratt
Biochemical characterization of the protective membrane glycoprotein GP46/M-2 of Leishmania amazonensis.
Molecular and biochemical parasitology 1991;47(2):235-43.
1991: Gabriel Grimaldi; Hooman Momen; Roberto D Naiff; Diane McMahon-Pratt; Toby V Barrett
Characterization and classification of leishmanial parasites from humans, wild mammals, and sand flies in the Amazon region of Brazil.
The American journal of tropical medicine and hygiene 1991;44(6):645-61.
1990: J H LeBowitz; C M Coburn; Diane McMahon-Pratt; Stephen M Beverley
Development of a stable Leishmania expression vector and application to the study of parasite surface antigen genes.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(24):9736-40.
1990: K L Lohman; P J Langer; Diane McMahon-Pratt
Molecular cloning and characterization of the immunologically protective surface glycoprotein GP46/M-2 of Leishmania amazonensis.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(21):8393-7.
1990: A H Lopes; D Iovannisci; M Petrillo-Peixoto; Diane McMahon-Pratt; Stephen M Beverley
Evolution of nuclear DNA and the occurrence of sequences related to new small chromosomal DNAs in the trypanosomatid genus Endotrypanum.
Molecular and biochemical parasitology 1990;40(2):151-61.
1990: C A Hanham; J J Shaw; R Lainson; Diane McMahon-Pratt
Production of a specific monoclonal antibody for the identification of Leishmania (Leishmania) venezuelensis.
The American journal of tropical medicine and hygiene 1990;42(5):453-9.
1989: Gabriel Grimaldi; R B Tesh; Diane McMahon-Pratt
A review of the geographic distribution and epidemiology of leishmaniasis in the New World.
The American journal of tropical medicine and hygiene 1989;41(6):687-725.
1989: R Ismach; C M Cianci; J P Caulfield; P J Langer; A Hein; Diane McMahon-Pratt
Flagellar membrane and paraxial rod proteins of Leishmania: characterization employing monoclonal antibodies.
The Journal of protozoology 1989;36(6):617-24.
1989: Alon Warburg; Robert B Tesh; Diane McMahon-Pratt
Studies on the attachment of Leishmania flagella to sand fly midgut epithelium.
The Journal of protozoology 1989;36(6):613-7.
1989: S Eperon; Diane McMahon-Pratt
Extracellular cultivation and morphological characterization of amastigote-like forms of Leishmania panamensis and L. braziliensis.
The Journal of protozoology 1989;36(5):502-10.
1989: S Eperon; Diane McMahon-Pratt
Extracellular amastigote-like forms of Leishmania panamensis and L. braziliensis. II. Stage- and species-specific monoclonal antibodies.
The Journal of protozoology 1989;36(5):510-8.
1989: Alfred A Pan; Diane McMahon-Pratt
Amastigote and epimastigote stage-specific components of Trypanosoma cruzi characterized by using monoclonal antibodies. Purification and molecular characterization of an 83-kilodalton amastigote protein.
Journal of immunology (Baltimore, Md. : 1950) 1989;143(3):1001-8.
1989: A H Lopes; Diane McMahon-Pratt
Monoclonal antibodies specific for members of the genus Endotrypanum.
The Journal of protozoology 1989;36(4):354-61.
1988: J Champsi; Diane McMahon-Pratt
Membrane glycoprotein M-2 protects against Leishmania amazonensis infection.
Infection and immunity 1988;56(12):3272-9.
1988: A C White; Diane McMahon-Pratt
Purification and characterization of an 80-kilodalton membrane protein from Leishmania donovani.
Infection and immunity 1988;56(9):2385-91.
1988: Charles L Jaffe; Diane McMahon-Pratt
The identification of membrane glycoconjugates in Leishmania species.
The Journal of parasitology 1988;74(4):548-61.
1988: Alfred A Pan; Diane McMahon-Pratt
Monoclonal antibodies specific for the amastigote stage of Leishmania pifanoi. I. Characterization of antigens associated with stage- and species-specific determinants.
Journal of immunology (Baltimore, Md. : 1950) 1988;140(7):2406-14.
1987: Charles L Jaffe; Diane McMahon-Pratt
Serodiagnostic assay for visceral leishmaniasis employing monoclonal antibodies.
Transactions of the Royal Society of Tropical Medicine and Hygiene 1987;81(4):587-94.
1986: Manoel Paes Oliveira-Neto; Gabriel Grimaldi; Hooman Momen; Raquel S Pacheco; Mauro C A Marzochi; Diane McMahon-Pratt
Active cutaneous leishmaniasis in Brazil, induced by Leishmania donovani chagasi.
Memórias do Instituto Oswaldo Cruz 1986;81(3):303-9.
1985: Hooman Momen; Gabriel Grimaldi; Raquel S Pacheco; Charles L Jaffe; Diane McMahon-Pratt; Mauro C A Marzochi
Brazilian Leishmania stocks phenotypically similar to Leishmania major.
The American journal of tropical medicine and hygiene 1985;34(6):1076-84.
1984: Alfred A Pan; Diane McMahon-Pratt; B M Honigberg
Leishmania mexicana pifanoi: antigenic characterization of promastigote and amastigote stages by solid phase radioimmunoassay.
The Journal of parasitology 1984;70(5):834-5.
1984: Charles L Jaffe; E Bennett; G Grimaldi; Diane McMahon-Pratt
Production and characterization of species-specific monoclonal antibodies against Leishmania donovani for immunodiagnosis.
Journal of immunology (Baltimore, Md. : 1950) 1984;133(1):440-7.
1984: G Grimaldi; Charles L Jaffe; Diane McMahon-Pratt; A Falqueto
A simple procedure for the isolation of leishmanial parasites and for the recovery of parasite virulence in avirulent stocks.
Transactions of the Royal Society of Tropical Medicine and Hygiene 1984;78(4):560.
1983: Charles L Jaffe; Diane McMahon-Pratt
Monoclonal antibodies specific for Leishmania tropica. I. Characterization of antigens associated with stage- and species-specific determinants.
Journal of immunology (Baltimore, Md. : 1950) 1983;131(4):1987-93.
1982: Diane McMahon-Pratt; E Bennett; J R David
Monoclonal antibodies that distinguish subspecies of Leishmania braziliensis.
Journal of immunology (Baltimore, Md. : 1950) 1982;129(3):926-7.