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Andrew McMichael

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Nilu Goonetilleke; Andrew J McMichael
HIV-1 vaccines: let's get physical.
Timothy J Powell; Sarah L Rowland-Jones; Tamara K Berthoud; Marie-Eve Blais; Sarah C Gilbert; Adrian V S Hill; Patrick J Lillie; Andrew J McMichael; Yanchun Peng; Tao Dong
Examination of Influenza Specific T Cell Responses after Influenza Virus Challenge in Individuals Vaccinated with MVA-NP+M1 Vaccine.
Yan Zhao; Laura Denney; Ling-Pei Ho; Yvonne Kendrick; Ning Li; Andrew J McMichael; Yan-Chun Peng; Tim J Powell; Yue-Long Shu; Da-Yan Wang; Hui-Ping Yan; Duncan Young; Yong-Hong Zhang; Tao Dong
High levels of virus-specific CD4+ T cells predict severe pandemic influenza A virus infection.

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All Publications

2013: Nilu Goonetilleke; Andrew J McMichael
HIV-1 vaccines: let's get physical.
Immunity 2013;38(3):410-3.
2013: Timothy J Powell; Sarah L Rowland-Jones; Tamara K Berthoud; Marie-Eve Blais; Sarah C Gilbert; Adrian V S Hill; Patrick J Lillie; Andrew J McMichael; Yanchun Peng; Tao Dong
Examination of Influenza Specific T Cell Responses after Influenza Virus Challenge in Individuals Vaccinated with MVA-NP+M1 Vaccine.
PloS one 2013;8(5):e62778.
2012: Yan Zhao; Laura Denney; Ling-Pei Ho; Yvonne Kendrick; Ning Li; Andrew J McMichael; Yan-Chun Peng; Tim J Powell; Yue-Long Shu; Da-Yan Wang; Hui-Ping Yan; Duncan Young; Yong-Hong Zhang; Tao Dong
High levels of virus-specific CD4+ T cells predict severe pandemic influenza A virus infection.
American journal of respiratory and critical care medicine 2012;186(12):1292-7.
2012: Guillaume B Stewart-Jones; P Anton van der Merwe; Philippa Easterbrook; E Yvonne Jones; Andrew J McMichael; Sarah L Rowland-Jones; Peter Simpson; Geraldine M Gillespie
Structural features underlying T-cell receptor sensitivity to concealed MHC class I micropolymorphisms.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(50):E3483-92.
2012: Ushani S Rajapaksa; Tao Dong; Demin Li; Andrew J McMichael; Yan-Chun Peng; Xiao-Ning Xu
HLA-B may be more protective against HIV-1 than HLA-A because it resists negative regulatory factor (Nef) mediated down-regulation.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(33):13353-8.
2012: Stephanie A Freel; Barton F Haynes; John C Kappes; Jennifer L Kirchherr; Andrew J McMichael; Christina Ochsenbauer; Ralph A Picking; Kelly A Soderberg; Myron S Cohen; John A Crump; Coleen K Cunningham; Thomas N Denny; Haitao Ding; Guido Ferrari; Kent J Weinhold; Georgia D Tomaras
Initial HIV-1 antigen-specific CD8+ T cells in acute HIV-1 infection inhibit transmitted/founder virus replication.
Journal of virology 2012;86(12):6835-46.
2012: Andrew J McMichael; Barton F Haynes
Lessons learned from HIV-1 vaccine trials: new priorities and directions.
Nature immunology 2012;13(5):423-7.
2012: Catherine Riou; Victoria E Whale; Michael R Betts; Persephone Borrow; Suzanne Campion; Guido Ferrari; Vitaly V Ganusov; Nilu Goonetilleke; Barton F Haynes; Michael K P Liu; Andrew J McMichael; Mandla Mlotshwa; Clive Gray
Distinct kinetics of Gag-specific CD4+ and CD8+ T cell responses during acute HIV-1 infection.
Journal of immunology (Baltimore, Md. : 1950) 2012;188(5):2198-206.
2012: Maximillian Rosario; Guillaume B Stewart-Jones; Nicola Borthwick; Anne Bridgeman; Stefano Colloca; Jan W Drijfhout; Alice Mbewe-Mvula; Andrew J McMichael; Cornelis J M Melief; David Montefiori; Alfredo Nicosia; Esther D Quakkelaar; Tomás Hanke
Prime-boost regimens with adjuvanted synthetic long peptides elicit T cells and antibodies to conserved regions of HIV-1 in macaques.
AIDS (London, England) 2012;26(3):275-84.
2012: Peter D Simpson; Kritika Sudan; Kate Wicks; Julian Knight; Andrew J McMichael; Eirini Moysi; Sarah L Rowland-Jones; Geraldine M Gillespie
Functional differences exist between TNFα promoters encoding the common -237G SNP and the rarer HLA-B*5701-linked A variant.
PloS one 2012;7(7):e40100.
2012: Adam J Ritchie; Z Maggie Wang; Christine Watera; Esther F Birabwa; Julie Fox; Nilu Goonetilleke; Jennifer Serwanga; Kristin Kuldanek; Kenneth Legg; Andrew J McMichael; Zoe Moodie; Rebecca N Nsubuga; Sarah Fidler
Comparison of sexual behavior and HIV risk between two HIV-1 serodiscordant couple cohorts: the CHAVI 002 study.
PloS one 2012;7(5):e37727.
2011: Tomáš Hanke; Andrew J McMichael
HIV-1: from escapism to conservatism.
European journal of immunology 2011;41(12):3390-3.
2011: Vitaly V Ganusov; Nilu Goonetilleke; Bette T Korber; Michael K P Liu; Andrew J McMichael; Persephone Borrow; Guido Ferrari; George M Shaw; Alan S Perelson
Fitness costs and diversity of the cytotoxic T lymphocyte (CTL) response determine the rate of CTL escape during acute and chronic phases of HIV infection.
Journal of virology 2011;85(20):10518-28.
2011: Simon Brackenridge; Edward J Evans; Mireille Toebes; Nilu Goonetilleke; Michael K P Liu; katalin di gleria; Ton N Schumacher; Simon J Davis; Andrew J McMichael; Geraldine M A Gillespie
An early HIV mutation within an HLA-B*57-restricted T cell epitope abrogates binding to the killer inhibitory receptor 3DL1.
Journal of virology 2011;85(11):5415-22.
2011: Myron S Cohen; George M Shaw; Andrew J McMichael; Barton F Haynes
Acute HIV-1 Infection.
The New England journal of medicine 2011;364(20):1943-54.
2011: Eung-Jun Im; Jessie P Hong; Yaowaluck Roshorm; Anne Bridgeman; Sven Létourneau; Peter Liljeström; Mary Jane Potash; David J Volsky; Andrew J McMichael; Tomáš Hanke
Protective efficacy of serially up-ranked subdominant CD8+ T cell epitopes against virus challenges.
PLoS pathogens 2011;7(5):e1002041.
2011: Srinika R F Ranasinghe; Holger B Kramer; Cynthia Wright; Benedikt M Kessler; katalin di gleria; Yonghong Zhang; Geraldine M A Gillespie; Marie-Eve Blais; Abigail Culshaw; Tica Pichulik; Alison Simmons; Sarah L Rowland-Jones; Andrew J McMichael; Tao Dong
The antiviral efficacy of HIV-specific CD8⁺ T-cells to a conserved epitope is heavily dependent on the infecting HIV-1 isolate.
PLoS pathogens 2011;7(5):e1001341.
2011: Adam J Ritchie; Suzanne L Campion; Jakub Kopycinski; Zoe Moodie; Z Maggie Wang; Kruti Pandya; Stephen Moore; Michael K P Liu; Simon Brackenridge; Kristin Kuldanek; Kenneth Legg; Myron S Cohen; Eric L Delwart; Barton F Haynes; Sarah Fidler; Andrew J McMichael; Nilu Goonetilleke
Differences in HIV-specific T cell responses between HIV-exposed and -unexposed HIV-seronegative individuals.
Journal of virology 2011;85(7):3507-16.
2011: Kambez Hajipouran Benam; Wai Ling Kok; Andrew J McMichael; Ling-Pei Ho
Alternative spliced CD1d transcripts in human bronchial epithelial cells.
PloS one 2011;6(8):e22726.
2011: Guido Ferrari; Bette Korber; Nilu Goonetilleke; Michael K P Liu; Emma L Turnbull; Jesus F Salazar-Gonzalez; Natalie Hawkins; Steve Self; Sydeaka Watson; Michael R Betts; Cynthia Gay; Kara McGhee; Pierre Pellegrino; Ian Williams; Georgia D Tomaras; Barton F Haynes; Clive M Gray; Persephone Borrow; Mario Roederer; Andrew J McMichael; Kent J Weinhold
Relationship between functional profile of HIV-1 specific CD8 T cells and epitope variability with the selection of escape mutants in acute HIV-1 infection.
PLoS pathogens 2011;7(2):e1001273.
2011: Suzanne Campion; Myron S Cohen; Andrew J McMichael; Shannon Galvin; Nilu Goonetilleke
Improved detection of latent Mycobacterium tuberculosis infection in HIV-1 seropositive individuals using cultured cellular assays.
European journal of immunology 2011;41(1):255-7.
2010: Andrew J McMichael; E Yvonne Jones
Genetics. First-class control of HIV-1.
Science (New York, N.Y.) 2010;330(6010):1488-90.
2010: Maximillian Rosario; Anne Bridgeman; Esther D Quakkelaar; Maire F Quigley; Brenna J Hill; Maria L Knudsen; Virginia Ammendola; Karl Ljungberg; Nicola Borthwick; Eung-Jun Im; Andrew J McMichael; Jan W Drijfhout; Hui Yee Greenaway; Vanessa Venturi; Daniel C Douek; Stefano Colloca; Peter Liljeström; Alfredo Nicosia; David A Price; Cornelis J M Melief; Tomás Hanke
Long peptides induce polyfunctional T cells against conserved regions of HIV-1 with superior breadth to single-gene vaccines in macaques.
European journal of immunology 2010;40(7):1973-84.
2010: Helen E Lockstone; Sharon Sanderson; Nina Kulakova; Dilair Baban; Andrew Leonard; Wai Ling Kok; Simon McGowan; Andrew J McMichael; Ling-Pei Ho
Gene set analysis of lung samples provides insight into pathogenesis of progressive, fibrotic pulmonary sarcoidosis.
American journal of respiratory and critical care medicine 2010;181(12):1367-75.
2010: Holger B Kramer; Kerry J Lavender; Li Qin; Andrea R Stacey; Michael K P Liu; katalin di gleria; Alison Simmons; Nancy Gasper-Smith; Barton F Haynes; Andrew J McMichael; Persephone Borrow; Benedikt M Kessler
Elevation of intact and proteolytic fragments of acute phase proteins constitutes the earliest systemic antiviral response in HIV-1 infection.
PLoS pathogens 2010;6(5):e1000893.
2010: Yuelong Shu; Chris Ka-fai Li; Zi Li; Rongbao Gao; Qian Liang; Ye Zhang; Libo Dong; Jiangfang Zhou; Jie Dong; Dayan Wang; Leying Wen; Ming Wang; Tian Bai; Dexin Li; Xiaoping Dong; Hongjie Yu; Weizhong Yang; Yu Wang; Zijian Feng; Andrew J McMichael; Xiao-Ning Xu
Avian influenza A(H5N1) viruses can directly infect and replicate in human gut tissues.
The Journal of infectious diseases 2010;201(8):1173-7.
2010: Will Fischer; Vitaly V Ganusov; Elena E Giorgi; Peter T Hraber; Brandon F Keele; Thomas Leitner; Cliff S Han; Cheryl D Gleasner; Lance Green; Chien-Chi Lo; Ambarish Nag; Timothy C Wallstrom; shuyi wang; Andrew J McMichael; Barton F Haynes; Beatrice H Hahn; Alan S Perelson; Persephone Borrow; George M Shaw; Tanmoy Bhattacharya; Bette T Korber
Transmission of single HIV-1 genomes and dynamics of early immune escape revealed by ultra-deep sequencing.
PloS one 2010;5(8):e12303.
2010: Laura Denney; Celia Aitken; Chris Ka-Fai Li; Eleri Wilson-Davies; Wai Ling Kok; Colin Clelland; Kevin Rooney; Duncan Young; Tao Dong; Andrew J McMichael; William F Carman; Ling-Pei Ho
Reduction of natural killer but not effector CD8 T lymphocytes in three consecutive cases of severe/lethal H1N1/09 influenza A virus infection.
PloS one 2010;5(5):e10675.
2010: Andrew J McMichael; Persephone Borrow; Georgia D Tomaras; Nilu Goonetilleke; Barton F Haynes
The immune response during acute HIV-1 infection: clues for vaccine development.
Nature reviews. Immunology 2010;10(1):11-23.
2010: N Kulakova; B Urban; Andrew J McMichael; Ling-Pei Ho
Functional analysis of dendritic cell-T cell interaction in sarcoidosis.
Clinical and experimental immunology 2010;159(1):82-6.
2009: Yaowaluck Roshorm; Jessie P Hong; Naoki Kobayashi; Andrew J McMichael; David J Volsky; Mary Jane Potash; Masafumi Takiguchi; Tomás Hanke
Novel HIV-1 clade B candidate vaccines designed for HLA-B*5101(+) patients protected mice against chimaeric ecotropic HIV-1 challenge.
European journal of immunology 2009;39(7):1831-40.
2009: Nilu Goonetilleke; Michael K P Liu; Jesus F Salazar-Gonzalez; Guido Ferrari; Elena Giorgi; Vitaly V Ganusov; Brandon F Keele; Gerald Learn; Emma L Turnbull; Maria G Salazar; Kent J Weinhold; Stephen Moore; Norman Letvin; Barton F Haynes; Myron S Cohen; Peter Hraber; Tanmoy Bhattacharya; Persephone Borrow; Alan S Perelson; Beatrice H Hahn; George M Shaw; Bette T Korber; Andrew J McMichael
The first T cell response to transmitted/founder virus contributes to the control of acute viremia in HIV-1 infection.
The Journal of experimental medicine 2009;206(6):1253-72.
2009: Nicola Winstone; Ana Guimarães-Walker; Joanna Roberts; Denise Brown; Vanessa Loach; Nilu Goonetilleke; Tomás Hanke; Andrew J McMichael
Increased detection of proliferating, polyfunctional, HIV-1-specific T cells in DNA-modified vaccinia virus Ankara-vaccinated human volunteers by cultured IFN-gamma ELISPOT assay.
European journal of immunology 2009;39(4):975-85.
2009: Denise Teoh; Louise A Johnson; Tomas Hanke; Andrew J McMichael; David G Jackson
Blocking development of a CD8+ T cell response by targeting lymphatic recruitment of APC.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(4):2425-31.
2009: Sarah C Bangs; Dilair Baban; Helen J Cattan; Chris Ka-Fi Li; Andrew J McMichael; Xiao-Ning Xu
Human CD4+ memory T cells are preferential targets for bystander activation and apoptosis.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(4):1962-71.
2008: Chris Ka-fai Li; Hao Wu; Huiping Yan; Shiwu Ma; Lili Wang; Mingxia Zhang; Xiaoping Tang; Nigel J Temperton; Robin A Weiss; Jason M Brenchley; Daniel C Douek; Juthathip Mongkolsapaya; Bac-Hai Tran; Chen-Lung Steve Lin; Gavin Screaton; Jin-lin Hou; Andrew J McMichael; Xiao-Ning Xu
T cell responses to whole SARS coronavirus in humans.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(8):5490-500.
2008: Laurel Yong-Hwa Lee; Do Lien Anh Ha; Cameron Simmons; Menno D De Jong; Nguyen Van Vinh Chau; Reto Schumacher; Yan Chun Peng; Andrew J McMichael; Jeremy J Farrar; Geoffrey L Smith; Alain R M Townsend; Brigitte A Askonas; Sarah Rowland-Jones; Tao Dong
Memory T cells established by seasonal human influenza A infection cross-react with avian influenza A (H5N1) in healthy individuals.
The Journal of clinical investigation 2008;118(10):3478-90.
2008: Andrew E Armitage; Aris Katzourakis; Tulio de Oliveira; John J Welch; Robert Belshaw; Kate N Bishop; Beatrice Kramer; Andrew J McMichael; Andrew Rambaut; Astrid K N Iversen
Conserved footprints of APOBEC3G on Hypermutated human immunodeficiency virus type 1 and human endogenous retrovirus HERV-K(HML2) sequences.
Journal of virology 2008;82(17):8743-61.
2008: Andrew E Armitage; Andrew J McMichael; Hal Drakesmith
Reflecting on a quarter century of HIV research.
Nature immunology 2008;9(8):823-6.
2008: Ling-Pei Ho; Laura Denney; Kerstin Luhn; Denise Teoh; Colin Clelland; Andrew J McMichael
Activation of invariant NKT cells enhances the innate immune response and improves the disease course in influenza A virus infection.
European journal of immunology 2008;38(7):1913-22.
2008: Anna Katharina Simon; Tom Newsom-Davis; Matthew E F Frayne; Paul F-T Ch'en; Andrew J McMichael; Gavin Screaton
Generation of tumour-rejecting anti-carbohydrate monoclonal antibodies using melanoma modified with Fas ligand.
International immunology 2008;20(4):525-34.
2008: Jeffrey Ishizuka; Guillaume Stewart-Jones; Philip van der Merwe; John I Bell; Andrew J McMichael; E Yvonne Jones
The structural dynamics and energetics of an immunodominant T cell receptor are programmed by its Vbeta domain.
Immunity 2008;28(2):171-82.
2008: Melody G Duvall; Melissa L Precopio; David A Ambrozak; Assan Jaye; Andrew J McMichael; Hilton C Whittle; Mario Roederer; Sarah L Rowland-Jones; Richard A Koup
Polyfunctional T cell responses are a hallmark of HIV-2 infection.
European journal of immunology 2008;38(2):350-63.
2008: Demin Li; Nan Chen; Andrew J McMichael; Gavin Screaton; Xiao-Ning Xu
Generation and characterisation of CD1d tetramer produced by a lentiviral expression system.
Journal of immunological methods 2008;330(1-2):57-63.
2007: Melody G Duvall; Karin Loré; Hetty Blaak; David A Ambrozak; William C Adams; Kathlyn Santos; Christof Geldmacher; John R Mascola; Andrew J McMichael; Assan Jaye; Hilton C Whittle; Sarah L Rowland-Jones; Richard A Koup
Dendritic cells are less susceptible to human immunodeficiency virus type 2 (HIV-2) infection than to HIV-1 infection.
Journal of virology 2007;81(24):13486-98.
2007: Andrew J McMichael
Triple bypass: complicated paths to HIV escape.
The Journal of experimental medicine 2007;204(12):2785-8.
2007: Andrew J McMichael
From influenza to HIV--and back?
Nature immunology 2007;8(11):1149-51.
2007: Jennifer H Cox; Andrew J McMichael; Gavin Screaton; Xiao-Ning Xu
CTLs target Th cells that acquire bystander MHC class I-peptide complex from APCs.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(2):830-6.
2007: Kerstin Lühn; Cameron P Simmons; Edward Moran; Nguyen Thi Dung; Tran Nguyen Bich Chau; Nguyen Than Ha Quyen; Le Thi Thu Thao; Tran Van Ngoc; Nguyen Minh Dung; Bridget Wills; Jeremy Farrar; Andrew J McMichael; Tao Dong; Sarah Rowland-Jones
Increased frequencies of CD4+ CD25(high) regulatory T cells in acute dengue infection.
The Journal of experimental medicine 2007;204(5):979-85.
2007: Barry S Peters; Walter Jaoko; Eftyhia Vardas; George Panayotakopoulos; Patricia E Fast; Claudia Schmidt; Jill Gilmour; Mampedi Bogoshi; Gloria Omosa-Manyonyi; Len Dally; Linda Klavinskis; Bashir Farah; Tony Tarragona; Pierre-Alexandre Bart; Andrew Robinson; Colleen Pieterse; Wendy Stevens; Richard Thomas; Burc Barin; Andrew J McMichael; James McIntyre; Giuseppe Pantaleo; Tomás Hanke; Job Bwayo
Studies of a prophylactic HIV-1 vaccine candidate based on modified vaccinia virus Ankara (MVA) with and without DNA priming: effects of dosage and route on safety and immunogenicity.
Vaccine 2007;25(11):2120-7.
2007: Natasha Larke; Eung-Jun Im; Ralf Wagner; Carolyn Williamson; Anna-Lise Williamson; Andrew J McMichael; Tomás Hanke
Combined single-clade candidate HIV-1 vaccines induce T cell responses limited by multiple forms of in vivo immune interference.
European journal of immunology 2007;37(2):566-77.
2007: Christopher Chiu; Adrian G Heaps; Vincenzo Cerundolo; Andrew J McMichael; Charles R M Bangham; Margaret F C Callan
Early acquisition of cytolytic function and transcriptional changes in a primary CD8+ T-cell response in vivo.
Blood 2007;109(3):1086-94.
2007: Sven Létourneau; Eung-Jun Im; Tumelo Mashishi; Choechoe Brereton; Anne Bridgeman; Hongbing Yang; Lucy Dorrell; Tao Dong; Bette Korber; Andrew J McMichael; Tomás Hanke
Design and pre-clinical evaluation of a universal HIV-1 vaccine.
PloS one 2007;2(10):e984.
2007: Annika C Karlsson; Astrid K N Iversen; Joan M Chapman; Tulio de Oliviera; Gerald Spotts; Andrew J McMichael; Miles P Davenport; Frederick Hecht; Douglas F Nixon
Sequential broadening of CTL responses in early HIV-1 infection is associated with viral escape.
PloS one 2007;2(2):e225.
2007: Tomás Hanke; Nilu Goonetilleke; Andrew J McMichael; Lucy Dorrell
Clinical experience with plasmid DNA- and modified vaccinia virus Ankara-vectored human immunodeficiency virus type 1 clade A vaccine focusing on T-cell induction.
The Journal of general virology 2007;88(Pt 1):1-12.
2006: Sarah C Bangs; Andrew J McMichael; Xiao-Ning Xu
Bystander T cell activation--implications for HIV infection and other diseases.
Trends in immunology 2006;27(11):518-24.
2006: Beatrice Ondondo; Hongbing Yang; Tao Dong; katalin di gleria; Annie Suttill; Christopher Conlon; Denise Brown; Patricia Williams; Sarah L Rowland-Jones; Tomás Hanke; Andrew J McMichael; Lucy Dorrell
Immunisation with recombinant modified vaccinia virus Ankara expressing HIV-1 gag in HIV-1-infected subjects stimulates broad functional CD4+ T cell responses.
European journal of immunology 2006;36(10):2585-94.
2006: Eung-Jun Im; Joseph Nkolola; katalin di gleria; Andrew J McMichael; Tomás Hanke
Induction of long-lasting multi-specific CD8+ T cells by a four-component DNA-MVA/HIVA-RENTA candidate HIV-1 vaccine in rhesus macaques.
European journal of immunology 2006;36(10):2574-84.
2006: Geraldine M A Gillespie; Guillaume Stewart-Jones; Jaya Rengasamy; Tara Beattie; Job J Bwayo; Francis A Plummer; Rupert Kaul; Andrew J McMichael; Philippa Easterbrook; Tao Dong; E Yvonne Jones; Sarah L Rowland-Jones
Strong TCR conservation and altered T cell cross-reactivity characterize a B*57-restricted immune response in HIV-1 infection.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(6):3893-902.
2006: Melody G Duvall; Assan Jaye; Tao Dong; Jason M Brenchley; Abraham Alabi; David J Jeffries; Marianne A B van der Sande; Toyin O Togun; Samuel J McConkey; Daniel C Douek; Andrew J McMichael; Hilton C Whittle; Richard A Koup; Sarah L Rowland-Jones
Maintenance of HIV-specific CD4+ T cell help distinguishes HIV-2 from HIV-1 infection.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(11):6973-81.
2006: Nilu Goonetilleke; Stephen Moore; Len Dally; Nicola Winstone; Inese Cebere; Abdul Mahmoud; Susana Pinheiro; Geraldine Gillespie; Denise Brown; Vanessa Loach; Joanna Roberts; Ana Guimaraes-Walker; Peter Hayes; Kelley Loughran; Carole Smith; Jan De Bont; Carl Verlinde; Danii Vooijs; Claudia Schmidt; Mark Boaz; Jill Gilmour; Patricia E Fast; Lucy Dorrell; Tomás Hanke; Andrew J McMichael
Induction of multifunctional human immunodeficiency virus type 1 (HIV-1)-specific T cells capable of proliferation in healthy subjects by using a prime-boost regimen of DNA- and modified vaccinia virus Ankara-vectored vaccines expressing HIV-1 Gag coupled to CD8+ T-cell epitopes.
Journal of virology 2006;80(10):4717-28.
2006: Tim Willinger; Tom Freeman; Mark Herbert; Hitoshi Hasegawa; Andrew J McMichael; Margaret F C Callan
Human naive CD8 T cells down-regulate expression of the WNT pathway transcription factors lymphoid enhancer binding factor 1 and transcription factor 7 (T cell factor-1) following antigen encounter in vitro and in vivo.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(3):1439-46.
2006: Astrid K N Iversen; Guillaume Stewart-Jones; Gerald Learn; Natasha Christie; Christina Sylvester-Hviid; Andrew E Armitage; Rupert Kaul; Tara Beattie; Jean K Lee; Yanping Li; Pojchong Chotiyarnwong; Tao Dong; Xiaoning Xu; Mark A Luscher; Kelly MacDonald; Henrik Ullum; Bente Klarlund Pedersen; Peter Skinhøj; Lars Fugger; Soren Buus; James I Mullins; E Yvonne Jones; Philip van der Merwe; Andrew J McMichael
Conflicting selective forces affect T cell receptor contacts in an immunodominant human immunodeficiency virus epitope.
Nature immunology 2006;7(2):179-89.
2006: Nan Chen; Corinna McCarthy; Hal Drakesmith; Demin Li; Vincenzo Cerundolo; Andrew J McMichael; Gavin Screaton; Xiao-Ning Xu
HIV-1 down-regulates the expression of CD1d via Nef.
European journal of immunology 2006;36(2):278-86.
2006: Inese Cebere; Lucy Dorrell; Helen McShane; Alison Simmons; Sheena McCormack; Claudia Schmidt; Carol Smith; Mary Brooks; Joanna E Roberts; Simon C Darwin; Patricia E Fast; Christopher Conlon; Sarah Rowland-Jones; Andrew J McMichael; Tomás Hanke
Phase I clinical trial safety of DNA- and modified virus Ankara-vectored human immunodeficiency virus type 1 (HIV-1) vaccines administered alone and in a prime-boost regime to healthy HIV-1-uninfected volunteers.
Vaccine 2006;24(4):417-25.
2006: Andrew J McMichael
HIV vaccines.
Annual review of immunology 2006;24():227-55.
2005: Natasha Larke; Aileen Murphy; Christoph Wirblich; Denise Teoh; Marie J Estcourt; Andrew J McMichael; Polly Roy; Tomás Hanke
Induction of human immunodeficiency virus type 1-specific T cells by a bluetongue virus tubule-vectored vaccine prime-recombinant modified virus Ankara boost regimen.
Journal of virology 2005;79(23):14822-33.
2005: Marie J Estcourt; Andrew J McMichael; Tomás Hanke
Altered primary CD8+ T cell response to a modified virus Ankara(MVA)-vectored vaccine in the absence of CD4+ T cell help.
European journal of immunology 2005;35(12):3460-7.
2005: Tim Willinger; Tom Freeman; Hitoshi Hasegawa; Andrew J McMichael; Margaret F C Callan
Molecular signatures distinguish human central memory from effector memory CD8 T cell subsets.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(9):5895-903.
2005: Elisabeth Amyes; Andrew J McMichael; Margaret F C Callan
Human CD4+ T cells are predominantly distributed among six phenotypically and functionally distinct subsets.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(9):5765-73.
2005: Jennifer A Slyker; Barbara L Lohman; Dorothy Mbori-Ngacha; Marie Reilly; Edmund G-T Wee; Tao Dong; Andrew J McMichael; Sarah L Rowland-Jones; Tomás Hanke; Grace C John-Stewart
Modified vaccinia Ankara expressing HIVA antigen stimulates HIV-1-specific CD8 T cells in ELISpot assays of HIV-1 exposed infants.
Vaccine 2005;23(38):4711-9.
2005: Marie J Estcourt; Sven Létourneau; Andrew J McMichael; Tomás Hanke
Vaccine route, dose and type of delivery vector determine patterns of primary CD8+ T cell responses.
European journal of immunology 2005;35(9):2532-40.
2005: Guillaume Stewart-Jones; Geraldine Gillespie; Ian M Overton; Rupert Kaul; Philippe Roche; Andrew J McMichael; Sarah Rowland-Jones; E Yvonne Jones
Structures of three HIV-1 HLA-B*5703-peptide complexes and identification of related HLAs potentially associated with long-term nonprogression.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(4):2459-68.
2005: Lucy Dorrell; Hongbing Yang; Astrid Kn Iversen; Christopher Conlon; Annie Suttill; Mary Lancaster; Tao Dong; Inese Cebere; Anne Edwards; Sarah Rowland-Jones; Tomás Hanke; Andrew J McMichael
Therapeutic immunization of highly active antiretroviral therapy-treated HIV-1-infected patients: safety and immunogenicity of an HIV-1 gag/poly-epitope DNA vaccine.
AIDS (London, England) 2005;19(12):1321-3.
2005: Astrid K N Iversen; Gerald Learn; Peter Skinhøj; James I Mullins; Andrew J McMichael; Andrew Rambaut
Preferential detection of HIV subtype C' over subtype A in cervical cells from a dually infected woman.
AIDS (London, England) 2005;19(9):990-3.
2005: Ling-Pei Ho; Britta C Urban; David R Thickett; Robert J O Davies; Andrew J McMichael
Deficiency of a subset of T-cells with immunoregulatory properties in sarcoidosis.
Lancet 2005;365(9464):1062-72.
2005: Tomás Hanke; Andrew J McMichael; Mike J Dennis; Sally A Sharpe; Lindsey A J Powell; Lorraine McLoughlin; Steven J Crome
Biodistribution and persistence of an MVA-vectored candidate HIV vaccine in SIV-infected rhesus macaques and SCID mice.
Vaccine 2005;23(12):1507-14.
2005: Guillaume Stewart-Jones; katalin di gleria; Simon Kollnberger; Andrew J McMichael; E Yvonne Jones; Paul Bowness
Crystal structures and KIR3DL1 recognition of three immunodominant viral peptides complexed to HLA-B*2705.
European journal of immunology 2005;35(2):341-51.
2005: Kathryn Poon; Damien Montamat-Sicotte; Nicole Cumberbatch; Andrew J McMichael; Margaret F C Callan
Expression of leukocyte immunoglobulin-like receptors and natural killer receptors on virus-specific CD8+ T cells during the evolution of Epstein-Barr virus-specific immune responses in vivo.
Viral immunology 2005;18(3):513-22.
2004: Tao Dong; Guillaume Stewart-Jones; Nan Chen; Philippa Easterbrook; Xiaoning Xu; Laura Papagno; Victor Appay; Michael Weekes; Christopher Conlon; Celsa A Spina; Susan Little; Gavin Screaton; Philip van der Merwe; Douglas D Richman; Andrew J McMichael; E Yvonne Jones; Sarah L Rowland-Jones
HIV-specific cytotoxic T cells from long-term survivors select a unique T cell receptor.
The Journal of experimental medicine 2004;200(12):1547-57.
2004: Jean K Lee; Guillaume Stewart-Jones; Tao Dong; Karl Harlos; katalin di gleria; Lucy Dorrell; Daniel C Douek; Philip van der Merwe; E Yvonne Jones; Andrew J McMichael
T cell cross-reactivity and conformational changes during TCR engagement.
The Journal of experimental medicine 2004;200(11):1455-66.
2004: Sophie Hambleton; Najl V Valeyev; Andreas Muranyi; Vroni Knott; Joern Werner; Andrew J McMichael; Penny A Handford; A Kristina Downing
Structural and functional properties of the human notch-1 ligand binding region.
Structure (London, England : 1993) 2004;12(12):2173-83.
2004: Rupert Kaul; John Rutherford; Sarah L Rowland-Jones; Joshua Kimani; James Isaiah Onyango; Keith R Fowke; Kelly MacDonald; Job J Bwayo; Andrew J McMichael; Francis A Plummer
HIV-1 Env-specific cytotoxic T-lymphocyte responses in exposed, uninfected Kenyan sex workers: a prospective analysis.
AIDS (London, England) 2004;18(15):2087-9.
2004: Simon Kollnberger; Lucy A Bird; Matthew Roddis; Cécile Hacquard-Bouder; Hiromi Kubagawa; Helen C Bodmer; Maxime Breban; Andrew J McMichael; Paul Bowness
HLA-B27 heavy chain homodimers are expressed in HLA-B27 transgenic rodent models of spondyloarthritis and are ligands for paired Ig-like receptors.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(3):1699-710.
2004: Michaela Lucas; Cheryl L Day; Jessica R Wyer; Sharon L Cunliffe; Andrew Loughry; Andrew J McMichael; Paul Klenerman
Ex vivo phenotype and frequency of influenza virus-specific CD4 memory T cells.
Journal of virology 2004;78(13):7284-7.
2004: Joseph Nkolola; Edmund G-T Wee; Eung-Jun Im; C P Jewell; N Chen; Xiao-Ning Xu; Andrew J McMichael; Tomás Hanke
Engineering RENTA, a DNA prime-MVA boost HIV vaccine tailored for Eastern and Central Africa.
Gene therapy 2004;11(13):1068-80.
2004: Ling-Pei Ho; Britta C Urban; Louise Jones; Graham S Ogg; Andrew J McMichael
CD4(-)CD8alphaalpha subset of CD1d-restricted NKT cells controls T cell expansion.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(12):7350-8.
2004: Marie J Estcourt; Andrew J McMichael; Tomás Hanke
DNA vaccines against human immunodeficiency virus type 1.
Immunological reviews 2004;199():144-55.
2004: Matilu Mwau; Inese Cebere; Julian Sutton; Priscilla Chikoti; Nicola Winstone; Edmund G-T Wee; Tara Beattie; Yun-Hsiang Chen; Lucy Dorrell; Helen McShane; Claudia Schmidt; Mary Brooks; Sandip Patel; Joanna Roberts; Christopher Conlon; Sarah L Rowland-Jones; Job J Bwayo; Andrew J McMichael; Tomás Hanke
A human immunodeficiency virus 1 (HIV-1) clade A vaccine in clinical trials: stimulation of HIV-specific T-cell responses by DNA and recombinant modified vaccinia virus Ankara (MVA) vaccines in humans.
The Journal of general virology 2004;85(Pt 4):911-9.
2004: Laura Papagno; Celsa A Spina; Arnaud Marchant; Mariolina Salio; Nathalie Rufer; Susan Little; Tao Dong; Gillian Chesney; Anele Waters; Philippa Easterbrook; P Rod Dunbar; Dawn Shepherd; Vincenzo Cerundolo; Vincent Emery; Paul Griffiths; Christopher Conlon; Andrew J McMichael; Douglas D Richman; Sarah L Rowland-Jones; Victor Appay
Immune activation and CD8+ T-cell differentiation towards senescence in HIV-1 infection.
PLoS biology 2004;2(2):E20.
2004: Matthew Roddis; Robert W Carter; Mei-Yi Sun; Thomas Weissensteiner; Andrew J McMichael; Paul Bowness; Helen C Bodmer
Fully functional HLA B27-restricted CD4+ as well as CD8+ T cell responses in TCR transgenic mice.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(1):155-61.
2003: Elisabeth Amyes; Chris Hatton; Damien Montamat-Sicotte; Nancy H Gudgeon; Alan B Rickinson; Andrew J McMichael; Margaret F C Callan
Characterization of the CD4+ T cell response to Epstein-Barr virus during primary and persistent infection.
The Journal of experimental medicine 2003;198(6):903-11.
2003: Felicity A Bland; Marius K Lemberg; Andrew J McMichael; Bruno Martoglio; Veronique M Braud
Requirement of the proteasome for the trimming of signal peptide-derived epitopes presented by the nonclassical major histocompatibility complex class I molecule HLA-E.
The Journal of biological chemistry 2003;278(36):33747-52.
2003: Edward J Evans; Lawrence Hene; Lisa M Sparks; Tao Dong; Christelle Retiere; Janet A Fennelly; Raquel Manso-Sancho; Jill Powell; Veronique M Braud; Sarah L Rowland-Jones; Andrew J McMichael; Simon J Davis
The T cell surface--how well do we know it?
Immunity 2003;19(2):213-23.
2003: Andrew J McMichael; Tomás Hanke
HIV vaccines 1983-2003.
Nature medicine 2003;9(7):874-80.
2003: Guillaume Stewart-Jones; Andrew J McMichael; John I Bell; David I Stuart; E Yvonne Jones
A structural basis for immunodominant human T cell receptor recognition.
Nature immunology 2003;4(7):657-63.
2003: Arnaud Marchant; Victor Appay; Marianne A B van der Sande; Nicolas Dulphy; Corinne Liesnard; Michael Kidd; Steve Kaye; Olubukola Ojuola; Geraldine M A Gillespie; Ana L Vargas Cuero; Vincenzo Cerundolo; Margaret F C Callan; Keith P W J McAdam; Sarah L Rowland-Jones; Catherine Donner; Andrew J McMichael; Hilton Whittle
Mature CD8(+) T lymphocyte response to viral infection during fetal life.
The Journal of clinical investigation 2003;111(11):1747-55.
2003: Lucy A Bird; Chen Au Peh; Simon Kollnberger; Tim Elliott; Andrew J McMichael; Paul Bowness
Lymphoblastoid cells express HLA-B27 homodimers both intracellularly and at the cell surface following endosomal recycling.
European journal of immunology 2003;33(3):748-59.
2003: Matilu Mwau; Andrew J McMichael
A review of vaccines for HIV prevention.
The journal of gene medicine 2003;5(1):3-10.
2002: Sharon L Cunliffe; Jessica R Wyer; Julian K Sutton; Michaela Lucas; Gillian Harcourt; Paul Klenerman; Andrew J McMichael; Anthony D Kelleher
Optimization of peptide linker length in production of MHC class II/peptide tetrameric complexes increases yield and stability, and allows identification of antigen-specific CD4+T cells in peripheral blood mononuclear cells.
European journal of immunology 2002;32(12):3366-75.
2002: Tomás Hanke; Andrew J McMichael; Rachel V Samuel; L A J Powell; L McLoughlin; S J Crome; A Edlin
Lack of toxicity and persistence in the mouse associated with administration of candidate DNA- and modified vaccinia virus Ankara (MVA)-based HIV vaccines for Kenya.
Vaccine 2002;21(1-2):108-14.
2002: Debbie Van Baarle; Stefan Kostense; Egbert Hovenkamp; Graham S Ogg; Nening M Nanlohy; Margaret F C Callan; Nicole Dukers; Andrew J McMichael; Marinus H J van Oers; Frank Miedema
Lack of Epstein-Barr virus- and HIV-specific CD27- CD8+ T cells is associated with progression to viral disease in HIV-infection.
AIDS (London, England) 2002;16(15):2001-11.
2002: David S J Allan; Eric J M Lepin; Veronique M Braud; Christopher A O'Callaghan; Andrew J McMichael
Tetrameric complexes of HLA-E, HLA-F, and HLA-G.
Journal of immunological methods 2002;268(1):43-50.
2002: Matilu Mwau; Andrew J McMichael; Tomás Hanke
Design and validation of an enzyme-linked immunospot assay for use in clinical trials of candidate HIV vaccines.
AIDS research and human retroviruses 2002;18(9):611-8.
2002: Victor Appay; John J Zaunders; Laura Papagno; Julian Sutton; Angel Jaramillo; Anele Waters; Philippa Easterbrook; Pat Grey; Don Smith; Andrew J McMichael; David A Cooper; Sarah L Rowland-Jones; Anthony D Kelleher
Characterization of CD4(+) CTLs ex vivo.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(11):5954-8.
2002: Rupert Kaul; Sarah L Rowland-Jones; Geraldine Gillespie; Joshua Kimani; Tao Dong; Peter Kiama; J Neil Simonsen; Job J Bwayo; Andrew J McMichael; Francis A Plummer
Gonococcal cervicitis is associated with reduced systemic CD8+ T cell responses in human immunodeficiency virus type 1-infected and exposed, uninfected sex workers.
The Journal of infectious diseases 2002;185(10):1525-9.
2002: Tomás Hanke; Andrew J McMichael; Matilu Mwau; Edmund G-T Wee; Inese Ceberej; Sandip Patel; Julian Sutton; Maxine Tomlinson; Rachel V Samuel
Development of a DNA-MVA/HIVA vaccine for Kenya.
Vaccine 2002;20(15):1995-8.
2002: Geraldine M A Gillespie; Rupert Kaul; Tao Dong; Hong-Bing Yang; Tim Rostron; Job J Bwayo; Peter Kiama; T E A Peto; Francis A Plummer; Andrew J McMichael; Sarah L Rowland-Jones
Cross-reactive cytotoxic T lymphocytes against a HIV-1 p24 epitope in slow progressors with B*57.
AIDS (London, England) 2002;16(7):961-72.
2002: Victor Appay; P Rod Dunbar; Margaret F C Callan; Paul Klenerman; Geraldine M A Gillespie; Laura Papagno; Graham S Ogg; Abigail King; Franziska Lechner; Celsa A Spina; Susan Little; Diane V Havlir; Douglas D Richman; Norbert H Gruener; Gerd R Pape; Anele Waters; Philippa Easterbrook; Mariolina Salio; Vincenzo Cerundolo; Andrew J McMichael; Sarah L Rowland-Jones
Memory CD8+ T cells vary in differentiation phenotype in different persistent virus infections.
Nature medicine 2002;8(4):379-85.
2002: Victor Appay; Laura Papagno; Celsa A Spina; Pokrath Hansasuta; Abigail King; Louise Jones; Graham S Ogg; Susan Little; Andrew J McMichael; Douglas D Richman; Sarah L Rowland-Jones
Dynamics of T cell responses in HIV infection.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(7):3660-6.
2002: Miles P Davenport; Chrysa Fazou; Andrew J McMichael; Margaret F C Callan
Clonal selection, clonal senescence, and clonal succession: the evolution of the T cell response to infection with a persistent virus.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(7):3309-17.
2002: Victor Appay; Pokrath Hansasuta; Julian Sutton; Rachel D Schrier; Joseph Wong; Manohar R Furtado; Diane V Havlir; Steven Wolinsky; Andrew J McMichael; Douglas D Richman; Sarah L Rowland-Jones; Celsa A Spina
Persistent HIV-1-specific cellular responses despite prolonged therapeutic viral suppression.
AIDS (London, England) 2002;16(2):161-70.
2002: Edmund G-T Wee; Sandip Patel; Andrew J McMichael; Tomás Hanke
A DNA/MVA-based candidate human immunodeficiency virus vaccine for Kenya induces multi-specific T cell responses in rhesus macaques.
The Journal of general virology 2002;83(Pt 1):75-80.
2001: Xiao-Ning Xu; Gavin Screaton; Andrew J McMichael
Virus infections: escape, resistance, and counterattack.
Immunity 2001;15(6):867-70.
2001: Chrysa Fazou; H Yang; Andrew J McMichael; Margaret F C Callan
Epitope specificity of clonally expanded populations of CD8+ T cells found within the joints of patients with inflammatory arthritis.
Arthritis and rheumatism 2001;44(9):2038-45.
2001: Anthony D Kelleher; Bruce L Booth; Andrew K Sewell; A Oxenius; Vincenzo Cerundolo; Andrew J McMichael; Rodney E Phillips; David A Price
Effects of retroviral protease inhibitors on proteasome function and processing of HIV-derived MHC class I-restricted cytotoxic T lymphocyte epitopes.
AIDS research and human retroviruses 2001;17(11):1063-6.
2001: Debbie Van Baarle; Egbert Hovenkamp; Margaret F C Callan; Katja C Wolthers; Stefan Kostense; LC Tan; Hubert G M Niesters; Albert D M E Osterhaus; Andrew J McMichael; Marinus H J van Oers; Frank Miedema
Dysfunctional Epstein-Barr virus (EBV)-specific CD8(+) T lymphocytes and increased EBV load in HIV-1 infected individuals progressing to AIDS-related non-Hodgkin lymphoma.
Blood 2001;98(1):146-55.
2001: Xiao-Ning Xu; Marco A Purbhoo; N Chen; Juthathip Mongkolsapaya; J H Cox; UC Meier; Sabrina Tafuro; P Rod Dunbar; Andrew K Sewell; Christopher Hourigan; Victor Appay; Vincenzo Cerundolo; S R Burrows; Andrew J McMichael; Gavin Screaton
A novel approach to antigen-specific deletion of CTL with minimal cellular activation using alpha3 domain mutants of MHC class I/peptide complex.
Immunity 2001;14(5):591-602.
2001: Andrew J McMichael; S L Rowland-Jones
Cellular immune responses to HIV.
Nature 2001;410(6831):980-7.
2001: Anthony D Kelleher; C Long; Edward C Holmes; Rachel Allen; J Wilson; Christopher Conlon; Cassy Workman; Sunil Shaunak; Kara Olson; Philip J R Goulder; Christian Brander; Graham S Ogg; John Sullivan; Wayne B Dyer; I Jones; Andrew J McMichael; Sarah Rowland-Jones; Rodney E Phillips
Clustered mutations in HIV-1 gag are consistently required for escape from HLA-B27-restricted cytotoxic T lymphocyte responses.
The Journal of experimental medicine 2001;193(3):375-86.
2001: Sabrina Tafuro; UC Meier; P Rod Dunbar; E Yvonne Jones; G T Layton; M G Hunter; John I Bell; Andrew J McMichael
Reconstitution of antigen presentation in HLA class I-negative cancer cells with peptide-beta2m fusion molecules.
European journal of immunology 2001;31(2):440-9.
2001: Rupert Kaul; Sarah L Rowland-Jones; Joshua Kimani; Tao Dong; H B Yang; Peter Kiama; Tim Rostron; Ephantus Njagi; Job J Bwayo; Kelly S MacDonald; Andrew J McMichael; Francis A Plummer
Late seroconversion in HIV-resistant Nairobi prostitutes despite pre-existing HIV-specific CD8+ responses.
The Journal of clinical investigation 2001;107(3):341-9.
2000: E J Lepin; Judy Bastin; David S J Allan; Giovanna Roncador; Veronique M Braud; D Y Mason; Philip van der Merwe; Andrew J McMichael; John I Bell; S H Powis; Christopher A O'Callaghan
Functional characterization of HLA-F and binding of HLA-F tetramers to ILT2 and ILT4 receptors.
European journal of immunology 2000;30(12):3552-61.
2000: Margaret F C Callan; Chrysa Fazou; H Yang; Tim Rostron; K Poon; C Hatton; Andrew J McMichael
CD8(+) T-cell selection, function, and death in the primary immune response in vivo.
The Journal of clinical investigation 2000;106(10):1251-61.
2000: Andrew J McMichael; Margaret F C Callan; Victor Appay; Tomás Hanke; Graham S Ogg; Sarah Rowland-Jones
The dynamics of the cellular immune response to HIV infection: implications for vaccination.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2000;355(1400):1007-11.
2000: Victor Appay; Douglas F Nixon; Sean M Donahoe; Geraldine M A Gillespie; Tao Dong; Abigail King; Graham S Ogg; Hans M L Spiegel; Christopher Conlon; Celsa A Spina; Diane V Havlir; Douglas D Richman; Anele Waters; Philippa Easterbrook; Andrew J McMichael; Sarah L Rowland-Jones
HIV-specific CD8(+) T cells produce antiviral cytokines but are impaired in cytolytic function.
The Journal of experimental medicine 2000;192(1):63-75.
2000: A King; David S J Allan; Mark Bowen; S J Powis; S Joseph; S Verma; Susan E Hiby; Andrew J McMichael; YW Loke; Veronique M Braud
HLA-E is expressed on trophoblast and interacts with CD94/NKG2 receptors on decidual NK cells.
European journal of immunology 2000;30(6):1623-31.
2000: David S J Allan; Andrew J McMichael; Veronique M Braud
The ILT family of leukocyte receptors.
Immunobiology 2000;202(1):34-41.
2000: Andrew J McMichael; Graham S Ogg; J Wilson; Margaret F C Callan; Sophie Hambleton; Victor Appay; T Kelleher; Sarah Rowland-Jones
Memory CD8+ T cells in HIV infection.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2000;355(1395):363-7.
2000: Graham S Ogg; P Rod Dunbar; Vincenzo Cerundolo; Andrew J McMichael; Nick Lemoine; P Savage
Sensitization of tumour cells to lysis by virus-specific CTL using antibody-targeted MHC class I/peptide complexes.
British journal of cancer 2000;82(5):1058-62.
2000: JD Wilson; Graham S Ogg; Rachel Allen; C Davis; Sunil Shaunak; J Downie; Wayne B Dyer; Cassy Workman; S Sullivan; Andrew J McMichael; Sarah L Rowland-Jones
Direct visualization of HIV-1-specific cytotoxic T lymphocytes during primary infection.
AIDS (London, England) 2000;14(3):225-33.
2000: Rupert Kaul; Francis A Plummer; Joshua Kimani; Tao Dong; Peter Kiama; Tim Rostron; Ephantus Njagi; Kelly S MacDonald; Job J Bwayo; Andrew J McMichael; Sarah L Rowland-Jones
HIV-1-specific mucosal CD8+ lymphocyte responses in the cervix of HIV-1-resistant prostitutes in Nairobi.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(3):1602-11.
2000: LC Tan; A G Mowat; Chrysa Fazou; Tim Rostron; H Roskell; P Rod Dunbar; C Tournay; François Romagné; Marie-Alix Peyrat; Elisabeth Houssaint; Marc Bonneville; Alan B Rickinson; Andrew J McMichael; Margaret F C Callan
Specificity of T cells in synovial fluid: high frequencies of CD8(+) T cells that are specific for certain viral epitopes.
Arthritis research 2000;2(2):154-64.
2000: Hans M L Spiegel; Graham S Ogg; E DeFalcon; ME Sheehy; SP Monard; Patrick A J Haslett; G Gillespie; Sean M Donahoe; Henry Pollack; William Borkowsky; Andrew J McMichael; Douglas F Nixon
Human immunodeficiency virus type 1- and cytomegalovirus-specific cytotoxic T lymphocytes can persist at high frequency for prolonged periods in the absence of circulating peripheral CD4(+) T cells.
Journal of virology 2000;74(2):1018-22.
2000: Xia Jin; MA Demoitie; Sean M Donahoe; Graham S Ogg; Sebastian Bonhoeffer; WM Kakimoto; G Gillespie; P A Moss; W Dyer; Michael Kurilla; S R Riddell; J Downie; John Sullivan; Andrew J McMichael; C Workman; Douglas F Nixon
High frequency of cytomegalovirus-specific cytotoxic T-effector cells in HLA-A*0201-positive subjects during multiple viral coinfections.
The Journal of infectious diseases 2000;181(1):165-75.
1999: Andrew J McMichael; A Kelleher
The arrival of HLA class II tetramers.
The Journal of clinical investigation 1999;104(12):1669-70.
1999: Graham S Ogg; Stefan Kostense; Michel Klein; Suzanne Jurriaans; Dörte Hamann; Andrew J McMichael; Frank Miedema
Longitudinal phenotypic analysis of human immunodeficiency virus type 1-specific cytotoxic T lymphocytes: correlation with disease progression.
Journal of virology 1999;73(11):9153-60.
1999: Tomás Hanke; R V Samuel; Tom J Blanchard; V C Neumann; T M Allen; Jonathan Boyson; Sally A Sharpe; Nicola Cook; Geoffrey L Smith; David Ian Watkins; Martin Cranage; Andrew J McMichael
Effective induction of simian immunodeficiency virus-specific cytotoxic T lymphocytes in macaques by using a multiepitope gene and DNA prime-modified vaccinia virus Ankara boost vaccination regimen.
Journal of virology 1999;73(9):7524-32.
1999: Hans M L Spiegel; E DeFalcon; Graham S Ogg; Marie Larsson; Thomas J Beadle; P Tao; Andrew J McMichael; Nina Bhardwaj; C O'Callaghan; W I Cox; Keith Krasinski; Henry Pollack; William Borkowsky; Douglas F Nixon
Changes in frequency of HIV-1-specific cytotoxic T cell precursors and circulating effectors after combination antiretroviral therapy in children.
The Journal of infectious diseases 1999;180(2):359-68.
1999: Marie Larsson; Xia Jin; Bharat Ramratnam; Graham S Ogg; J Engelmayer; MA Demoitie; Andrew J McMichael; WI Cox; Ralph M Steinman; D Nixon; Nina Bhardwaj
A recombinant vaccinia virus based ELISPOT assay detects high frequencies of Pol-specific CD8 T cells in HIV-1-positive individuals.
AIDS (London, England) 1999;13(7):767-77.
1999: Xiao-Ning Xu; Bernd Laffert; Gavin Screaton; M Kraft; D Wolf; Waldemar Kolanus; J Mongkolsapay; Andrew J McMichael; Andreas S Baur
Induction of Fas ligand expression by HIV involves the interaction of Nef with the T cell receptor zeta chain.
The Journal of experimental medicine 1999;189(9):1489-96.
1999: Rachel Allen; Christopher A O'Callaghan; Andrew J McMichael; Paul Bowness
Cutting edge: HLA-B27 can form a novel beta 2-microglobulin-free heavy chain homodimer structure.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(9):5045-8.
1999: David S J Allan; Marco COLONna; Lewis L Lanier; Tatyana Churakova; J S Abrams; S A Ellis; Andrew J McMichael; Veronique M Braud
Tetrameric complexes of human histocompatibility leukocyte antigen (HLA)-G bind to peripheral blood myelomonocytic cells.
The Journal of experimental medicine 1999;189(7):1149-56.
1999: G S Ogg; Andrew J McMichael
Quantitation of antigen-specific CD8+ T-cell responses.
Immunology letters 1999;66(1-3):77-80.
1999: Sarah L Rowland-Jones; Tao Dong; Lucy Dorrell; Graham S Ogg; Pokrath Hansasuta; P Krausa; Joshua Kimani; Saihou Sabally; Koya Ariyoshi; Julius Oyugi; Kelly S MacDonald; Job Bwayo; Hilton Whittle; Francis A Plummer; Andrew J McMichael
Broadly cross-reactive HIV-specific cytotoxic T-lymphocytes in highly-exposed persistently seronegative donors.
Immunology letters 1999;66(1-3):9-14.
1999: R Tan; X Xu; Graham S Ogg; Pokrath Hansasuta; Tao Dong; Tim Rostron; Graz Luzzi; Christopher Conlon; Gavin Screaton; Andrew J McMichael; Sarah Rowland-Jones
Rapid death of adoptively transferred T cells in acquired immunodeficiency syndrome.
Blood 1999;93(5):1506-10.
1999: Veronique M Braud; David S J Allan; Andrew J McMichael
Functions of nonclassical MHC and non-MHC-encoded class I molecules.
Current opinion in immunology 1999;11(1):100-8.
1999: LC Tan; Nancy H Gudgeon; Nicola E Annels; Pokrath Hansasuta; Christopher A O'Callaghan; Sarah Rowland-Jones; Andrew J McMichael; Alan B Rickinson; Margaret F C Callan
A re-evaluation of the frequency of CD8+ T cells specific for EBV in healthy virus carriers.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(3):1827-35.
1999: Lucy Dorrell; Tao Dong; Graham S Ogg; S Lister; S McAdam; Tim Rostron; Christopher Conlon; Andrew J McMichael; Sarah L Rowland-Jones
Distinct recognition of non-clade B human immunodeficiency virus type 1 epitopes by cytotoxic T lymphocytes generated from donors infected in Africa.
Journal of virology 1999;73(2):1708-14.
1999: Margaret F C Callan; Andrew J McMichael
T cell receptor usage in infectious disease.
Springer seminars in immunopathology 1999;21(1):37-54.
1999: Christopher A O'Callaghan; M F Byford; Jessica R Wyer; Benjamin E Willcox; Bent K Jakobsen; Andrew J McMichael; John I Bell
BirA enzyme: production and application in the study of membrane receptor-ligand interactions by site-specific biotinylation.
Analytical biochemistry 1999;266(1):9-15.
1999: Graham S Ogg; X Jin; Sebastian Bonhoeffer; P Moss; M A Nowak; SP Monard; J P Segal; Yunzhen Cao; Sarah L Rowland-Jones; Arlene Hurley; MH Markowitz; David D Ho; Andrew J McMichael; Douglas F Nixon
Decay kinetics of human immunodeficiency virus-specific effector cytotoxic T lymphocytes after combination antiretroviral therapy.
Journal of virology 1999;73(1):797-800.
1999: Wayne B Dyer; Graham S Ogg; MA Demoitie; Xia Jin; Andrew F Geczy; S L Rowland-Jones; Andrew J McMichael; Douglas F Nixon; John Sullivan
Strong human immunodeficiency virus (HIV)-specific cytotoxic T-lymphocyte activity in Sydney Blood Bank Cohort patients infected with nef-defective HIV type 1.
Journal of virology 1999;73(1):436-43.
1999: Juthathip Mongkolsapaya; Assan Jaye; M F Callan; AF Magnusen; Andrew J McMichael; Hilton C Whittle
Antigen-specific expansion of cytotoxic T lymphocytes in acute measles virus infection.
Journal of virology 1999;73(1):67-71.
1998: Margaret F C Callan; Nicola E Annels; Neil M Steven; L Tan; J Wilson; Andrew J McMichael; Alan B Rickinson
T cell selection during the evolution of CD8+ T cell memory in vivo.
European journal of immunology 1998;28(12):4382-90.
1998: Sarah L Rowland-Jones; Tao Dong; Keith R Fowke; Joshua Kimani; P Krausa; H Newell; Tom J Blanchard; Koya Ariyoshi; Julius Oyugi; Elizabeth Ngugi; Job Bwayo; Kelly S MacDonald; Andrew J McMichael; Francis A Plummer
Cytotoxic T cell responses to multiple conserved HIV epitopes in HIV-resistant prostitutes in Nairobi.
The Journal of clinical investigation 1998;102(9):1758-65.
1998: Paul Bowness; Rachel Allen; D N Barclay; E Yvonne Jones; Andrew J McMichael
Importance of a conserved TCR J alpha-encoded tyrosine for T cell recognition of an HLA B27/peptide complex.
European journal of immunology 1998;28(9):2704-13.
1998: JD Wilson; Graham S Ogg; Rachel Allen; Philip J R Goulder; Anthony D Kelleher; Andrew K Sewell; Christopher A O'Callaghan; Sarah L Rowland-Jones; Margaret F C Callan; Andrew J McMichael
Oligoclonal expansions of CD8(+) T cells in chronic HIV infection are antigen specific.
The Journal of experimental medicine 1998;188(4):785-90.
1998: G S Ogg; Andrew J McMichael
HLA-peptide tetrameric complexes.
Current opinion in immunology 1998;10(4):393-6.
1998: Margaret F C Callan; L Tan; Nicola E Annels; Graham S Ogg; JD Wilson; Christopher A O'Callaghan; Neil M Steven; Andrew J McMichael; Alan B Rickinson
Direct visualization of antigen-specific CD8+ T cells during the primary immune response to Epstein-Barr virus In vivo.
The Journal of experimental medicine 1998;187(9):1395-402.
1998: Andrew J McMichael; Christopher A O'Callaghan
A new look at T cells.
The Journal of experimental medicine 1998;187(9):1367-71.
1998: J D Wilson; Martin Cranage; Nicola Cook; Sharon Leech; Andrew J McMichael; Margaret F C Callan
Evidence for the persistence of monoclonal expansions of CD8+ T cells following primary simian immunodeficiency virus infection.
European journal of immunology 1998;28(4):1172-80.
1998: Graham S Ogg; X Jin; Sebastian Bonhoeffer; P R Dunbar; M A Nowak; SP Monard; J P Segal; Yunzhen Cao; Sarah L Rowland-Jones; Vincenzo Cerundolo; Arlene Hurley; MH Markowitz; David D Ho; Douglas F Nixon; Andrew J McMichael
Quantitation of HIV-1-specific cytotoxic T lymphocytes and plasma load of viral RNA.
Science (New York, N.Y.) 1998;279(5359):2103-6.
1998: Christopher A O'Callaghan; Jose Tormo; Benjamin E Willcox; Veronique M Braud; Bent K Jakobsen; David I Stuart; Andrew J McMichael; John I Bell; E Yvonne Jones
Structural features impose tight peptide binding specificity in the nonclassical MHC molecule HLA-E.
Molecular cell 1998;1(4):531-41.
1998: Veronique M Braud; David S J Allan; Christopher A O'Callaghan; K Söderström; A D'Andrea; Graham S Ogg; Sasha Lazetic; Neil T Young; John I Bell; Joseph H Phillips; Lewis L Lanier; Andrew J McMichael
HLA-E binds to natural killer cell receptors CD94/NKG2A, B and C.
Nature 1998;391(6669):795-9.
1998: V M Braud; Andrew J McMichael; Vincenzo Cerundolo
Differential processing of influenza nucleoprotein in human and mouse cells.
European journal of immunology 1998;28(2):625-35.
1998: Juthathip Mongkolsapaya; AE Cowper; Xiao-Ning Xu; G Morris; Andrew J McMichael; John I Bell; Gavin Screaton
Lymphocyte inhibitor of TRAIL (TNF-related apoptosis-inducing ligand): a new receptor protecting lymphocytes from the death ligand TRAIL.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(1):3-6.
1998: Veronique M Braud; David S J Allan; D Wilson; Andrew J McMichael
TAP- and tapasin-dependent HLA-E surface expression correlates with the binding of an MHC class I leader peptide.
Current biology : CB 1998;8(1):1-10.
1997: Ajit Lalvani; Tao Dong; Graham S Ogg; A A Patham; H Newell; Adrian V S Hill; Andrew J McMichael; Sarah Rowland-Jones
Optimization of a peptide-based protocol employing IL-7 for in vitro restimulation of human cytotoxic T lymphocyte precursors.
Journal of immunological methods 1997;210(1):65-77.
1997: Ajit Lalvani; Roger H Brookes; Sophie Hambleton; W J Britton; A V Hill; Andrew J McMichael
Rapid effector function in CD8+ memory T cells.
The Journal of experimental medicine 1997;186(6):859-65.
1997: Rachel Allen; Geraldine M A Gillespie; F Hall; S Edmonds; M A Hall; B Paul Wordsworth; Andrew J McMichael; Paul Bowness
Multiple T cell expansions are found in the blood and synovial fluid of patients with reactive arthritis.
The Journal of rheumatology 1997;24(9):1750-7.
1997: Gavin Screaton; Juthathip Mongkolsapaya; Xiao-Ning Xu; AE Cowper; Andrew J McMichael; John I Bell
TRICK2, a new alternatively spliced receptor that transduces the cytotoxic signal from TRAIL.
Current biology : CB 1997;7(9):693-6.
1997: Xiao-Ning Xu; Gavin Screaton; F M Gotch; Tao Dong; R Tan; Neil Almond; Kenneth Barry Walker; Richard Stebbings; K Kent; S Nagata; Jim Stott; Andrew J McMichael
Evasion of cytotoxic T lymphocyte (CTL) responses by nef-dependent induction of Fas ligand (CD95L) expression on simian immunodeficiency virus-infected cells.
The Journal of experimental medicine 1997;186(1):7-16.
1997: George F Gao; Jose Tormo; UC Gerth; Jessica R Wyer; Andrew J McMichael; David I Stuart; John I Bell; E Yvonne Jones; Bent K Jakobsen
Crystal structure of the complex between human CD8alpha(alpha) and HLA-A2.
Nature 1997;387(6633):630-4.
1997: Philip J R Goulder; S W Reid; David A Price; Christopher A O'Callaghan; Andrew J McMichael; Rodney E Phillips; E Y Jones
Combined structural and immunological refinement of HIV-1 HLA-B8-restricted cytotoxic T lymphocyte epitopes.
European journal of immunology 1997;27(6):1515-21.
1997: Gavin Screaton; Xiao-Ning Xu; A L Olsen; AE Cowper; R Tan; Andrew J McMichael; John I Bell
LARD: a new lymphoid-specific death domain containing receptor regulated by alternative pre-mRNA splicing.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(9):4615-9.
1997: Philip J R Goulder; Andrew K Sewell; David Lalloo; David A Price; JA Whelan; J Evans; G P Taylor; Graz Luzzi; P Giangrande; Rodney E Phillips; Andrew J McMichael
Patterns of immunodominance in HIV-1-specific cytotoxic T lymphocyte responses in two human histocompatibility leukocyte antigens (HLA)-identical siblings with HLA-A*0201 are influenced by epitope mutation.
The Journal of experimental medicine 1997;185(8):1423-33.
1997: S J Vessey; D H Barouch; S N McAdam; L G Tussey; M A Davenport; Christopher A O'Callaghan; John I Bell; Andrew J McMichael; Bent K Jakobsen
Engagement of a T cell receptor by major histocompatibility complex irrespective of peptide.
European journal of immunology 1997;27(4):879-85.
1997: Philip J R Goulder; Rodney E Phillips; Robert A Colbert; S McAdam; Graham S Ogg; Martin A Nowak; P Giangrande; Graz Luzzi; B Morgan; Anne Edwards; Andrew J McMichael; Sarah Rowland-Jones
Late escape from an immunodominant cytotoxic T-lymphocyte response associated with progression to AIDS.
Nature medicine 1997;3(2):212-7.
1997: Andrew J McMichael; Rodney E Phillips
Escape of human immunodeficiency virus from immune control.
Annual review of immunology 1997;15():271-96.
1996: Paul Klenerman; Rodney E Phillips; Charles Rinaldo; L M Wahl; Graham S Ogg; Robert M May; Andrew J McMichael; Martin A Nowak
Cytotoxic T lymphocytes and viral turnover in HIV type 1 infection.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(26):15323-8.
1996: Philip J R Goulder; Mike Bunce; P Krausa; K McIntyre; S Crowley; B Morgan; Anne Edwards; P L F Giangrande; Rodney E Phillips; Andrew J McMichael
Novel, cross-restricted, conserved, and immunodominant cytotoxic T lymphocyte epitopes in slow progressors in HIV type 1 infection.
AIDS research and human retroviruses 1996;12(18):1691-8.
1996: S W Reid; S McAdam; K J Smith; Paul Klenerman; Christopher A O'Callaghan; Karl Harlos; Bent K Jakobsen; Andrew J McMichael; John I Bell; David I Stuart; E Yvonne Jones
Antagonist HIV-1 Gag peptides induce structural changes in HLA B8.
The Journal of experimental medicine 1996;184(6):2279-86.
1996: Margaret F C Callan; Neil M Steven; P Krausa; J D Wilson; P A Moss; G M Gillespie; John I Bell; Alan B Rickinson; Andrew J McMichael
Large clonal expansions of CD8+ T cells in acute infectious mononucleosis.
Nature medicine 1996;2(8):906-11.
1996: S W Reid; K J Smith; Bent K Jakobsen; Christopher A O'Callaghan; H Reyburn; Karl Harlos; David I Stuart; Andrew J McMichael; John I Bell; E Yvonne Jones
Production and crystallization of MHC class I B allele single peptide complexes.
FEBS letters 1996;383(1-2):119-23.
1996: K J Smith; S W Reid; Karl Harlos; Andrew J McMichael; David I Stuart; John I Bell; E Yvonne Jones
Bound water structure and polymorphic amino acids act together to allow the binding of different peptides to MHC class I HLA-B53.
Immunity 1996;4(3):215-28.
1996: K J Smith; S W Reid; David I Stuart; Andrew J McMichael; E Yvonne Jones; John I Bell
An altered position of the alpha 2 helix of MHC class I is revealed by the crystal structure of HLA-B*3501.
Immunity 1996;4(3):203-13.
1996: K Toshitani; Veronique M Braud; M J Browning; N Murray; Andrew J McMichael; W F Bodmer
Expression of a single-chain HLA class I molecule in a human cell line: presentation of exogenous peptide and processed antigen to cytotoxic T lymphocytes.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(1):236-40.
1995: JS Haurum; L Tan; Gemma Arsequell; P Frodsham; A C Lellouch; P A Moss; Raymond A Dwek; Andrew J McMichael; Tim Elliott
Peptide anchor residue glycosylation: effect on class I major histocompatibility complex binding and cytotoxic T lymphocyte recognition.
European journal of immunology 1995;25(12):3270-6.
1995: Margaret F C Callan; G M Gillespie; H T Reyburn; P A Moss; John I Bell; Andrew J McMichael
Preferential expression of the human V beta 7.1 gene segment on CD8+ peripheral blood lymphocytes.
Annals of the New York Academy of Sciences 1995;756():94-5.
1995: UC Gerth; P A Moss; John I Bell; Andrew J McMichael
T-cell receptor usage of major histocompatibility complex class I restricted peptide-specific T-lymphocytes.
Annals of the New York Academy of Sciences 1995;756():12-8.
1995: Paul Klenerman; U C Meier; Rodney E Phillips; Andrew J McMichael
The effects of natural altered peptide ligands on the whole blood cytotoxic T lymphocyte response to human immunodeficiency virus.
European journal of immunology 1995;25(7):1927-31.
1995: L G Tussey; S Rowland-Jones; T S Zheng; M J Androlewicz; P Cresswell; Jeffrey Frelinger; Andrew J McMichael
Different MHC class I alleles compete for presentation of overlapping viral epitopes.
Immunity 1995;3(1):65-77.
1995: P A Moss; S L Rowland-Jones; P M Frodsham; S McAdam; P L F Giangrande; Andrew J McMichael; John I Bell
Persistent high frequency of human immunodeficiency virus-specific cytotoxic T cells in peripheral blood of infected donors.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(13):5773-7.
1995: Margaret F C Callan; H T Reyburn; Paul Bowness; S Rowland-Jones; John I Bell; Andrew J McMichael
Selection of T cell receptor variable gene-encoded amino acids on the third binding site loop: a factor influencing variable chain selection in a T cell response.
European journal of immunology 1995;25(6):1529-34.
1995: Ann B Hill; S P Lee; JS Haurum; N Murray; Q Y Yao; M Rowe; N Signoret; Alan B Rickinson; Andrew J McMichael
Class I major histocompatibility complex-restricted cytotoxic T lymphocytes specific for Epstein-Barr virus (EBV)-transformed B lymphoblastoid cell lines against which they were raised.
The Journal of experimental medicine 1995;181(6):2221-8.
1995: M Matsui; R J Moots; R J Warburton; Amy Brewer; L G Tussey; Daniel G Quinn; Andrew J McMichael; Jeffrey Frelinger
Genetic evidence for difference between intracellular and extracellular peptides in influenza A matrix peptide-specific CTL recognition.
Journal of immunology (Baltimore, Md. : 1950) 1995;154(3):1088-96.
1995: P Krausa; D Barouch; JG Bodmer; A V Hill; Carl Mason; Andrew J McMichael; M J Browning
Characterization of a novel HLA-A2 variant, A*0214, by ARMS-PCR and DNA sequencing.
Immunogenetics 1995;41(1):50.
1995: D Barouch; P Krausa; J Bodmer; M J Browning; Andrew J McMichael
Identification of a novel HLA-A2 subtype, HLA-A*0216.
Immunogenetics 1995;41(6):388.
1994: M Matsui; R J Moots; Andrew J McMichael; Jeffrey Frelinger
Significance of the six peptide-binding pockets of HLA-A2.1 in influenza A matrix peptide-specific cytotoxic T-lymphocyte reactivity.
Human immunology 1994;41(2):160-6.
1994: Paul Bowness; Rachel Allen; Andrew J McMichael
Identification of T cell receptor recognition residues for a viral peptide presented by HLA B27.
European journal of immunology 1994;24(10):2357-63.
1994: JS Haurum; Gemma Arsequell; A C Lellouch; S Y Wong; Raymond A Dwek; Andrew J McMichael; Tim Elliott
Recognition of carbohydrate by major histocompatibility complex class I-restricted, glycopeptide-specific cytotoxic T lymphocytes.
The Journal of experimental medicine 1994;180(2):739-44.
1994: Robert A Colbert; S L Rowland-Jones; Andrew J McMichael; Jeffrey Frelinger
Differences in peptide presentation between B27 subtypes: the importance of the P1 side chain in maintaining high affinity peptide binding to B*2703.
Immunity 1994;1(2):121-30.
1994: R J Warburton; M Matsui; S L Rowland-Jones; M C Gammon; G E Katzenstein; T Wei; M Edidin; H J Zweerink; Andrew J McMichael; Jeffrey Frelinger
Mutation of the alpha 2 domain disulfide bridge of the class I molecule HLA-A*0201. Effect on maturation and peptide presentation.
Human immunology 1994;39(4):261-71.
1994: Ann B Hill; B C Barnett; Andrew J McMichael; Duncan J McGeoch
HLA class I molecules are not transported to the cell surface in cells infected with herpes simplex virus types 1 and 2.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(6):2736-41.
1993: Frances Gotch; S McAdam; C E Allsopp; A Gallimore; J Elvin; M P Kieny; Adrian V S Hill; Andrew J McMichael; Hilton C Whittle
Cytotoxic T cells in HIV2 seropositive Gambians. Identification of a virus-specific MHC-restricted peptide epitope.
Journal of immunology (Baltimore, Md. : 1950) 1993;151(6):3361-9.
1993: S L Rowland-Jones; S H Powis; J Sutton; I Mockridge; F M Gotch; N Murray; Ann B Hill; W M Rosenberg; J Trowsdale; Andrew J McMichael
An antigen processing polymorphism revealed by HLA-B8-restricted cytotoxic T lymphocytes which does not correlate with TAP gene polymorphism.
European journal of immunology 1993;23(8):1999-2004.
1993: Robert A Colbert; S L Rowland-Jones; Andrew J McMichael; Jeffrey Frelinger
Allele-specific B pocket transplant in class I major histocompatibility complex protein changes requirement for anchor residue at P2 of peptide.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(14):6879-83.
1993: Paul Bowness; P A Moss; S Rowland-Jones; John I Bell; Andrew J McMichael
Conservation of T cell receptor usage by HLA B27-restricted influenza-specific cytotoxic T lymphocytes suggests a general pattern for antigen-specific major histocompatibility complex class I-restricted responses.
European journal of immunology 1993;23(7):1417-21.
1993: X M Gao; Cheryl Quinn; John I Bell; Andrew J McMichael
Expression and function of HLA-B27 in lipid-linked form: implications for cytotoxic T lymphocyte-induced apoptosis signal transduction.
European journal of immunology 1993;23(3):653-8.
1993: Rodney E Phillips; Andrew J McMichael
How does the HIV escape cytotoxic T cell immunity?
Chemical immunology 1993;56():150-64.
1992: Paul Bowness; P A Moss; H Tranter; John I Bell; Andrew J McMichael
Clostridium perfringens enterotoxin is a superantigen reactive with human T cell receptors V beta 6.9 and V beta 22.
The Journal of experimental medicine 1992;176(3):893-6.
1992: X M Gao; John Tite; M Lipscombe; S Rowland-Jones; D J Ferguson; Andrew J McMichael
Recombinant Salmonella typhimurium strains that invade nonphagocytic cells are resistant to recognition by antigen-specific cytotoxic T lymphocytes.
Infection and immunity 1992;60(9):3780-9.
1992: R J Moots; N L Samberg; L Pazmany; Jeffrey Frelinger; Andrew J McMichael; Hans J Stauss
A cross-species functional interaction between the murine major histocompatibility complex class I alpha 3 domain and human CD8 revealed by peptide-specific cytotoxic T lymphocytes.
European journal of immunology 1992;22(6):1643-6.
1992: Adrian V S Hill; C E Allsopp; Dominic Kwiatkowski; Terrie E Taylor; S N Yates; Nicholas Anstey; J J Wirima; D R Brewster; Andrew J McMichael; M E Molyneux
Extensive genetic diversity in the HLA class II region of Africans, with a focally predominant allele, DRB1*1304.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(6):2277-81.
1992: C E Allsopp; R M Harding; C Taylor; M Bunce; Dominic Kwiatkowski; N Anstey; D Brewster; Andrew J McMichael; Brian M Greenwood; Adrian V S Hill
Interethnic genetic differentiation in Africa: HLA class I antigens in The Gambia.
American journal of human genetics 1992;50(2):411-21.
1992: Andrew J McMichael
Role of class I molecules of the major histocompatibility complex in cytotoxic T-cell function in health and disease.
Springer seminars in immunopathology 1992;14(1):1-16.
1991: P A Moss; R J Moots; W M Rosenberg; S J Rowland-Jones; H C Bodmer; Andrew J McMichael; John I Bell
Extensive conservation of alpha and beta chains of the human T-cell antigen receptor recognizing HLA-A2 and influenza A matrix peptide.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(20):8987-90.
1991: Adrian V S Hill; C E Allsopp; Dominic Kwiatkowski; Nicholas Anstey; P Twumasi; P A Rowe; S Bennett; D Brewster; Andrew J McMichael; Brian M Greenwood
Common west African HLA antigens are associated with protection from severe malaria.
Nature 1991;352(6336):595-600.
1991: Adrian V S Hill; C E Allsopp; Dominic Kwiatkowski; Nicholas Anstey; Brian M Greenwood; Andrew J McMichael
HLA class I typing by PCR: HLA-B27 and an African B27 subtype.
Lancet 1991;337(8742):640-2.
1991: F M Gotch; R Hovell; Martine Delchambre; Peter Silvera; Andrew J McMichael
Cytotoxic T-cell response to simian immunodeficiency virus by cynomolgus macaque monkeys immunized with recombinant vaccinia virus.
AIDS (London, England) 1991;5(3):317-20.
1991: C E Allsopp; Adrian V S Hill; Dominic Kwiatkowski; A Hughes; M Bunce; C J Taylor; L Pazmany; D Brewster; Andrew J McMichael; Brian M Greenwood
Sequence analysis of HLA-Bw53, a common West African allele, suggests an origin by gene conversion of HLA-B35.
Human immunology 1991;30(2):105-9.
1991: P A Robbins; Andrew J McMichael
Immune recognition of HLA molecules downmodulates CD8 expression on cytotoxic T lymphocytes.
The Journal of experimental medicine 1991;173(1):221-30.
1991: R J Moots; M Matsui; L Pazmany; Andrew J McMichael; Jeffrey Frelinger
A cluster of mutations in HLA-A2 alpha 2 helix abolishes peptide recognition by T cells.
Immunogenetics 1991;34(3):141-8.
1990: Jeffrey Frelinger; F M Gotch; H Zweerink; E Wain; Andrew J McMichael
Evidence of widespread binding of HLA class I molecules to peptides.
The Journal of experimental medicine 1990;172(3):827-34.
1990: Douglas F Nixon; S Huet; J Rothbard; M P Kieny; Martine Delchambre; C Thiriart; C R Rizza; F M Gotch; Andrew J McMichael
An HIV-1 and HIV-2 cross-reactive cytotoxic T-cell epitope.
AIDS (London, England) 1990;4(9):841-5.
1990: S A Ellis; M S Palmer; Andrew J McMichael
Human trophoblast and the choriocarcinoma cell line BeWo express a truncated HLA Class I molecule.
Journal of immunology (Baltimore, Md. : 1950) 1990;144(2):731-5.
1990: S Huet; Douglas F Nixon; J B Rothbard; A Townsend; S A Ellis; Andrew J McMichael
Structural homologies between two HLA B27-restricted peptides suggest residues important for interaction with HLA B27.
International immunology 1990;2(4):311-6.
1990: F M Gotch; Douglas F Nixon; N Alp; Andrew J McMichael; L K Borysiewicz
High frequency of memory and effector gag specific cytotoxic T lymphocytes in HIV seropositive individuals.
International immunology 1990;2(8):707-12.
1989: P A Robbins; L A Lettice; P Rota; J Santos-Aguado; J Rothbard; Andrew J McMichael; Jack L Strominger
Comparison between two peptide epitopes presented to cytotoxic T lymphocytes by HLA-A2. Evidence for discrete locations within HLA-A2.
Journal of immunology (Baltimore, Md. : 1950) 1989;143(12):4098-103.
1989: D Isaacs; C J Taylor; A Ting; Andrew J McMichael
HLA class I antigens in severe RSV bronchiolitis.
Tissue antigens 1989;34(3):210-2.
1989: P A Reay; I M Jones; F M Gotch; Andrew J McMichael; George G Brownlee
Recognition of the PB1, neuraminidase, and matrix proteins of influenza virus A/NT/60/68 by cytotoxic T lymphocytes.
Virology 1989;170(2):477-85.
1989: S A Ellis; T Strachan; M S Palmer; Andrew J McMichael
Complete nucleotide sequence of a unique HLA class I C locus product expressed on the human choriocarcinoma cell line BeWo.
Journal of immunology (Baltimore, Md. : 1950) 1989;142(9):3281-5.
1989: H C Bodmer; F M Gotch; Andrew J McMichael
Class I cross-restricted T cells reveal low responder allele due to processing of viral antigen.
Nature 1989;337(6208):653-5.
1989: Jack L Strominger; J Santos-Aguado; Steven J Burakoff; M A Vega; F M Gotch; P A Robbins; Andrew J McMichael
Mutants of HLA-A2 in the analysis of its structure and function.
Cold Spring Harbor symposia on quantitative biology 1989;54 Pt 1():361-3.
1989: Douglas F Nixon; Andrew J McMichael
HIV-gag-specific cytotoxic T lymphocytes.
Research in immunology 1989;140(1):107-10; discussion 121.
1988: Andrew J McMichael; F M Gotch; J Santos-Aguado; Jack L Strominger
Effect of mutations and variations of HLA-A2 on recognition of a virus peptide epitope by cytotoxic T lymphocytes.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(23):9194-8.
1988: Douglas F Nixon; A R Townsend; J G Elvin; C R Rizza; J Gallwey; Andrew J McMichael
HIV-1 gag-specific cytotoxic T lymphocytes defined with recombinant vaccinia virus and synthetic peptides.
Nature 1988;336(6198):484-7.
1987: D Isaacs; C R Bangham; Andrew J McMichael
Cell-mediated cytotoxic response to respiratory syncytial virus in infants with bronchiolitis.
Lancet 1987;2(8562):769-71.
1987: S H Sacks; Andrew Bushell; N A Rust; J A Karagiannis; D P Jewell; J G Ledingham; Kathryn J Wood; Andrew J McMichael
Functional and biochemical subtypes of the haplotype HLA-DR3 in patients with celiac disease or idiopathic membranous nephropathy.
Human immunology 1987;20(2):175-87.
1986: Andrew J McMichael; F M Gotch; J Rothbard
HLA B37 determines an influenza A virus nucleoprotein epitope recognized by cytotoxic T lymphocytes.
The Journal of experimental medicine 1986;164(5):1397-406.
1986: A R Townsend; J Rothbard; F M Gotch; G Bahadur; D Wraith; Andrew J McMichael
The epitopes of influenza nucleoprotein recognized by cytotoxic T lymphocytes can be defined with short synthetic peptides.
Cell 1986;44(6):959-68.