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Douglas McMillin

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Douglas W McMillin; Joseph Negri; Constantine S Mitsiades
The role of tumour-stromal interactions in modifying drug response: challenges and opportunities.
Steffen Klippel; Jacob Laubach; Douglas W McMillin; Kenneth C Anderson; Jake Delmore; Jana Jakubikova; Efstathios Kastritis; Melissa Ooi; Paul G Richardson; Constantine S Mitsiades
Methyljasmonate displays in vitro and in vivo activity against multiple myeloma cells.
Michaela R Reagan; Elizabeth K Sage; F Philipp Seib; Irene M Ghobrial; Sam M Janes; Douglas W McMillin; Constantine S Mitsiades; David L Kaplan
Stem Cell Implants for Cancer Therapy: TRAIL-Expressing Mesenchymal Stem Cells Target Cancer Cells In Situ.

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All Publications

2013: Douglas W McMillin; Joseph Negri; Constantine S Mitsiades
The role of tumour-stromal interactions in modifying drug response: challenges and opportunities.
Nature reviews. Drug discovery 2013;12(3):217-28.
2012: Steffen Klippel; Jacob Laubach; Douglas W McMillin; Kenneth C Anderson; Jake Delmore; Jana Jakubikova; Efstathios Kastritis; Melissa Ooi; Paul G Richardson; Constantine S Mitsiades
Methyljasmonate displays in vitro and in vivo activity against multiple myeloma cells.
British journal of haematology 2012;159(3):340-51.
2012: Michaela R Reagan; Elizabeth K Sage; F Philipp Seib; Irene M Ghobrial; Sam M Janes; Douglas W McMillin; Constantine S Mitsiades; David L Kaplan
Stem Cell Implants for Cancer Therapy: TRAIL-Expressing Mesenchymal Stem Cells Target Cancer Cells In Situ.
Journal of breast cancer 2012;15(3):273-82.
2012: Shugeng Cao; Jake Delmore; Douglas W McMillin; Constantine S Mitsiades; Giselle Tamayo; Jon Clardy
Inhibition of tumor cells interacting with stromal cells by xanthones isolated from a Costa Rican Penicillium sp.
Journal of natural products 2012;75(4):793-7.
2011: Jana Jakubikova; Kihyun Kim; Steffen Klippel; Merav Leiba; Douglas W McMillin; Kenneth C Anderson; Simona Blotta; David Cervi; Dana Cholujova; John F Daley; Jake Delmore; Teru Hideshima; Sabikun Nahar; Joseph Negri; Melissa Ooi; Paul G Richardson; Jan Sedlak; Constantine S Mitsiades
Anti-tumor activity and signaling events triggered by the isothiocyanates, sulforaphane and phenethyl isothiocyanate, in multiple myeloma.
Haematologica 2011;96(8):1170-9.
2011: Douglas W McMillin; Jake Delmore; Joseph Negri; Leutz Buon; Hannah M Jacobs; Jacob Laubach; Jana Jakubikova; Melissa Ooi; Patrick Hayden; Robert Schlossman; Nikhil C Munshi; Christoph Lengauer; Paul G Richardson; Kenneth C Anderson; Constantine S Mitsiades
Molecular and cellular effects of multi-targeted cyclin-dependent kinase inhibition in myeloma: biological and clinical implications.
British journal of haematology 2011;152(4):420-32.
2011: Douglas W McMillin; Chandrasekhar V Miduturu; Joseph Negri; Melissa Ooi; Paul G Richardson; Kenneth C Anderson; Jake Delmore; Nathanael S Gray; Steffen Klippel; Andrew L Kung; Constantine S Mitsiades
Microenvironmental influence on pre-clinical activity of polo-like kinase inhibition in multiple myeloma: implications for clinical translation.
PloS one 2011;6(7):e20226.
2009: Joseph M Negri; Douglas W McMillin; Jake Delmore; Nicholas Mitsiades; Patrick Hayden; Steffen Klippel; Teru Hideshima; Dharminder Chauhan; Nikhil C Munshi; Carolyn A Buser; John Pollard; Paul G Richardson; Kenneth C Anderson; Constantine S Mitsiades
In vitro anti-myeloma activity of the Aurora kinase inhibitor VE-465.
British journal of haematology 2009;147(5):672-6.
2009: Douglas W McMillin; Melissa Ooi; Jake Delmore; Joseph Negri; Patrick J Hayden; Nicholas Mitsiades; Jana Jakubikova; Sauveur-Michel Maira; Carlos Garcia-Echeverria; Robert Schlossman; Nikhil C Munshi; Paul G Richardson; Kenneth C Anderson; Constantine S Mitsiades
Antimyeloma activity of the orally bioavailable dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor NVP-BEZ235.
Cancer research 2009;69(14):5835-42.
2008: Ellen Weisberg; Renee D Wright; Douglas W McMillin; Constantine S Mitsiades; Arghya Ray; Rosemary Barrett; Sophia Adamia; Richard M Stone; Ilene Galinsky; Andrew L Kung; James D Griffin
Stromal-mediated protection of tyrosine kinase inhibitor-treated BCR-ABL-expressing leukemia cells.
Molecular cancer therapeutics 2008;7(5):1121-9.
2007: Xavier Leleu; Xiaoying Jia; Judith M Runnels; Hai T Ngo; Anne-Sophie Moreau; Mena Farag; Joel A Spencer; Costas M Pitsillides; Evdoxia Hatjiharissi; Aldo Roccaro; Garrett O'Sullivan; Douglas W McMillin; Daisy Moreno; Tanyel Kiziltepe; Ruben D Carrasco; Steve P Treon; Teru Hideshima; Kenneth C Anderson; Charles P Lin; Irene M Ghobrial
The Akt pathway regulates survival and homing in Waldenstrom macroglobulinemia.
Blood 2007;110(13):4417-26.
2007: Constantine S Mitsiades; Douglas W McMillin; Steffen Klippel; Teru Hideshima; Dharminder Chauhan; Paul G Richardson; Nikhil C Munshi; Kenneth C Anderson
The role of the bone marrow microenvironment in the pathophysiology of myeloma and its significance in the development of more effective therapies.
Hematology/oncology clinics of North America 2007;21(6):1007-34, vii-viii.
2007: Constantine S Mitsiades; Patrick J Hayden; Vassiliki Kotoula; Douglas W McMillin; Ciaran McMullan; Joseph Negri; Jake E Delmore; Vassiliki Poulaki; Nicholas Mitsiades
Bcl-2 overexpression in thyroid carcinoma cells increases sensitivity to Bcl-2 homology 3 domain inhibition.
The Journal of clinical endocrinology and metabolism 2007;92(12):4845-52.
2007: Vassiliki Poulaki; Constantine S Mitsiades; Vassiliki Kotoula; Joseph Negri; Douglas W McMillin; Joan W Miller; Nicholas Mitsiades
The proteasome inhibitor bortezomib induces apoptosis in human retinoblastoma cell lines in vitro.
Investigative ophthalmology & visual science 2007;48(10):4706-19.
2007: Ellen Weisberg; Andrew L Kung; Renee D Wright; Daisy Moreno; Laurence Catley; Arghya Ray; Leigh Zawel; Mary Tran; Jan Cools; Gary Gilliland; Constantine S Mitsiades; Douglas W McMillin; Jingrui Jiang; Elizabeth Hall-Meyers; James D Griffin
Potentiation of antileukemic therapies by Smac mimetic, LBW242: effects on mutant FLT3-expressing cells.
Molecular cancer therapeutics 2007;6(7):1951-61.
2007: Constantine S Mitsiades; Joseph Negri; Ciaran McMullan; Douglas W McMillin; Elias Sozopoulos; Galinos Fanourakis; Gerassimos Voutsinas; Sofia Tseleni-Balafouta; Vassiliki Poulaki; David Batt; Nicholas Mitsiades
Targeting BRAFV600E in thyroid carcinoma: therapeutic implications.
Molecular cancer therapeutics 2007;6(3):1070-8.
2007: klaus podar; Marc S Raab; Jing Zhang; Douglas W McMillin; Iris Breitkreutz; Yu-Tzu Tai; Boris K Lin; Nikhil C Munshi; Teru Hideshima; Dharminder Chauhan; Kenneth C Anderson
Targeting PKC in multiple myeloma: in vitro and in vivo effects of the novel, orally available small-molecule inhibitor enzastaurin (LY317615.HCl).
Blood 2007;109(4):1669-77.
2006: Constantine S Mitsiades; Douglas W McMillin; Vassiliki Kotoula; Vassiliki Poulaki; Ciaran McMullan; Joseph Negri; Galinos Fanourakis; Sofia Tseleni-Balafouta; Kenneth B Ain; Nicholas Mitsiades
Antitumor effects of the proteasome inhibitor bortezomib in medullary and anaplastic thyroid carcinoma cells in vitro.
The Journal of clinical endocrinology and metabolism 2006;91(10):4013-21.
2006: Constantine S Mitsiades; Vassiliki Poulaki; Galinos Fanourakis; Elias Sozopoulos; Douglas W McMillin; Zhaoqin Wen; Gerassimos Voutsinas; Sofia Tseleni-Balafouta; Nicholas Mitsiades
Fas signaling in thyroid carcinomas is diverted from apoptosis to proliferation.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(12):3705-12.