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Linda McPhail

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Nicole Y Davis; Linda C McPhail; David A Horita
The NOXO1β PX domain preferentially targets PtdIns(4,5)P2 and PtdIns(3,4,5)P3.
Nicole Y Davis; Linda C McPhail; David A Horita
Backbone 1H, 15N, and 13C resonance assignments for the NOXO1β PX domain.
Eric M Lewis; S Sergeant; Bill Ledford; Natalie Stull; Mary C Dinauer; Linda C McPhail
Phosphorylation of p22phox on threonine 147 enhances NADPH oxidase activity by promoting p47phox binding.

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All Publications

2012: Nicole Y Davis; Linda C McPhail; David A Horita
The NOXO1β PX domain preferentially targets PtdIns(4,5)P2 and PtdIns(3,4,5)P3.
Journal of molecular biology 2012;417(5):440-53.
2011: Nicole Y Davis; Linda C McPhail; David A Horita
Backbone 1H, 15N, and 13C resonance assignments for the NOXO1β PX domain.
Biomolecular NMR assignments 2011;5(2):139-41.
2010: Eric M Lewis; S Sergeant; Bill Ledford; Natalie Stull; Mary C Dinauer; Linda C McPhail
Phosphorylation of p22phox on threonine 147 enhances NADPH oxidase activity by promoting p47phox binding.
The Journal of biological chemistry 2010;285(5):2959-67.
2008: Eric M Lewis; Manav Singla; S Sergeant; Patrick P Koty; Linda C McPhail
X-linked chronic granulomatous disease secondary to skewed X chromosome inactivation in a female with a novel CYBB mutation and late presentation.
Clinical immunology (Orlando, Fla.) 2008;129(2):372-80.
2008: Kai Shen; S Sergeant; Roy R Hantgan; Linda C McPhail; David A Horita
Mutations in the PX-SH3A linker of p47phox decouple PI(3,4)P2 binding from NADPH oxidase activation.
Biochemistry 2008;47(34):8855-65.
2008: Heidi J Chial; Ruping Wu; Carolyn V Ustach; Linda C McPhail; William C. Mobley; Yong Q Chen
Membrane targeting by APPL1 and APPL2: dynamic scaffolds that oligomerize and bind phosphoinositides.
Traffic (Copenhagen, Denmark) 2008;9(2):215-29.
2007: Ross M Taylor; Connie I Lord; Marcia H Riesselman; Jeannie M Gripentrog; Thomas L Leto; Linda C McPhail; Yevgeny Berdichevsky; Edgar Pick; Algirdas J Jesaitis
Characterization of surface structure and p47phox SH3 domain-mediated conformational changes for human neutrophil flavocytochrome b.
Biochemistry 2007;46(49):14291-304.
2007: S Sergeant; Linda C McPhail
Measurement of phospholipid metabolism in intact neutrophils.
Methods in molecular biology (Clifton, N.J.) 2007;412():69-83.
2004: Ross M Taylor; Thomas R Foubert; James B Burritt; Danas Baniulis; Linda C McPhail; Algirdas J Jesaitis
Anionic amphiphile and phospholipid-induced conformational changes in human neutrophil flavocytochrome b observed by fluorescence resonance energy transfer.
Biochimica et biophysica acta 2004;1663(1-2):201-13.
2001: S Sergeant; KA Waite; J Heravi; Linda C McPhail
Phosphatidic acid regulates tyrosine phosphorylating activity in human neutrophils: enhancement of Fgr activity.
The Journal of biological chemistry 2001;276(7):4737-46.
2001: Anita Palicz; Thomas R Foubert; Algirdas J Jesaitis; L Marodi; Linda C McPhail
Phosphatidic acid and diacylglycerol directly activate NADPH oxidase by interacting with enzyme components.
The Journal of biological chemistry 2001;276(5):3090-7.
2000: DS Regier; D G Greene; S Sergeant; Algirdas J Jesaitis; Linda C McPhail
Phosphorylation of p22phox is mediated by phospholipase D-dependent and -independent mechanisms. Correlation of NADPH oxidase activity and p22phox phosphorylation.
The Journal of biological chemistry 2000;275(37):28406-12.
2000: Anna Karlsson; JB Nixon; Linda C McPhail
Phorbol myristate acetate induces neutrophil NADPH-oxidase activity by two separate signal transduction pathways: dependent or independent of phosphatidylinositol 3-kinase.
Journal of leukocyte biology 2000;67(3):396-404.
1999: DS Regier; KA Waite; Reidar Wallin; Linda C McPhail
A phosphatidic acid-activated protein kinase and conventional protein kinase C isoforms phosphorylate p22(phox), an NADPH oxidase component.
The Journal of biological chemistry 1999;274(51):36601-8.
1999: JB Nixon; Linda C McPhail
Protein kinase C (PKC) isoforms translocate to Triton-insoluble fractions in stimulated human neutrophils: correlation of conventional PKC with activation of NADPH oxidase.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(8):4574-82.
1999: Linda C McPhail; KA Waite; DS Regier; JB Nixon; D Qualliotine-Mann; W X Zhang; Reidar Wallin; S Sergeant
A novel protein kinase target for the lipid second messenger phosphatidic acid.
Biochimica et biophysica acta 1999;1439(2):277-90.
1997: S Sergeant; Linda C McPhail
Opsonized zymosan stimulates the redistribution of protein kinase C isoforms in human neutrophils.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(6):2877-85.
1997: KA Waite; Reidar Wallin; D Qualliotine-Mann; Linda C McPhail
Phosphatidic acid-mediated phosphorylation of the NADPH oxidase component p47-phox. Evidence that phosphatidic acid may activate a novel protein kinase.
The Journal of biological chemistry 1997;272(24):15569-78.
1996: J D Kent; S Sergeant; D J Burns; Linda C McPhail
Identification and regulation of protein kinase C-delta in human neutrophils.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(10):4641-7.
1995: Linda C McPhail; D Qualliotine-Mann; KA Waite
Cell-free activation of neutrophil NADPH oxidase by a phosphatidic acid-regulated protein kinase.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(17):7931-5.
1994: Linda C McPhail
SH3-dependent assembly of the phagocyte NADPH oxidase.
The Journal of experimental medicine 1994;180(6):2011-5.
1994: Silvano Sozzani; D E Agwu; M D Ellenburg; Massimo Locati; M Rieppi; Armando Rojas; A Mantovani; Linda C McPhail
Activation of phospholipase D by interleukin-8 in human neutrophils.
Blood 1994;84(11):3895-901.
1993: D Qualliotine-Mann; D E Agwu; M D Ellenburg; Charles E McCall; Linda C McPhail
Phosphatidic acid and diacylglycerol synergize in a cell-free system for activation of NADPH oxidase from human neutrophils.
The Journal of biological chemistry 1993;268(32):23843-9.
1993: Linda C McPhail; D Qualliotine-Mann; D E Agwu; Charles E McCall
Phospholipases and activation of the NADPH oxidase.
European journal of haematology 1993;51(5):294-300.
1992: Silvano Sozzani; D E Agwu; Charles E McCall; Joseph T O'Flaherty; J D Schmitt; J D Kent; Linda C McPhail
Propranolol, a phosphatidate phosphohydrolase inhibitor, also inhibits protein kinase C.
The Journal of biological chemistry 1992;267(28):20481-8.
1992: M C Chabot; Linda C McPhail; Robert L Wykle; D A Kennerly; Charles E McCall
Comparison of diglyceride production from choline-containing phosphoglycerides in human neutrophils stimulated with N-formylmethionyl-leucylphenylalanine, ionophore A23187 or phorbol 12-myristate 13-acetate.
The Biochemical journal 1992;286 ( Pt 3)():693-9.
1992: Linda C McPhail; S L Strum; Peter A Leone; Silvano Sozzani
The neutrophil respiratory burst mechanism.
Immunology series 1992;57():47-76.
1991: D E Agwu; Linda C McPhail; Silvano Sozzani; David A Bass; Charles E McCall
Phosphatidic acid as a second messenger in human polymorphonuclear leukocytes. Effects on activation of NADPH oxidase.
The Journal of clinical investigation 1991;88(2):531-9.
1991: D E Agwu; Charles E McCall; Linda C McPhail
Regulation of phospholipase D-induced hydrolysis of choline-containing phosphoglycerides by cyclic AMP in human neutrophils.
Journal of immunology (Baltimore, Md. : 1950) 1991;146(11):3895-903.
1989: D E Agwu; Linda C McPhail; Robert L Wykle; Charles E McCall
Mass determination of receptor-mediated accumulation of phosphatidate and diglycerides in human neutrophils measured by Coomassie blue staining and densitometry.
Biochemical and biophysical research communications 1989;159(1):79-86.
1989: D E Agwu; Linda C McPhail; M C Chabot; Larry W Daniel; Robert L Wykle; Charles E McCall
Choline-linked phosphoglycerides. A source of phosphatidic acid and diglycerides in stimulated neutrophils.
The Journal of biological chemistry 1989;264(3):1405-13.
1988: David A Bass; Linda C McPhail; J D Schmitt; Susan L Morris-Natschke; Charles E McCall; Robert L Wykle
Selective priming of rate and duration of the respiratory burst of neutrophils by 1,2-diacyl and 1-O-alkyl-2-acyl diglycerides. Possible relation to effects on protein kinase C.
The Journal of biological chemistry 1988;263(36):19610-7.
1988: S E Caldwell; Charles E McCall; C L Hendricks; Peter A Leone; David A Bass; Linda C McPhail
Coregulation of NADPH oxidase activation and phosphorylation of a 48-kD protein(s) by a cytosolic factor defective in autosomal recessive chronic granulomatous disease.
The Journal of clinical investigation 1988;81(5):1485-96.
1987: L Harvath; Charles E McCall; David A Bass; Linda C McPhail
Inhibition of human neutrophil chemotaxis by the protein kinase inhibitor, 1-(5-isoquinolinesulfonyl) piperazine.
Journal of immunology (Baltimore, Md. : 1950) 1987;139(9):3055-61.
1987: David A Bass; C Gerard; P Olbrantz; J Wilson; Charles E McCall; Linda C McPhail
Priming of the respiratory burst of neutrophils by diacylglycerol. Independence from activation or translocation of protein kinase C.
The Journal of biological chemistry 1987;262(14):6643-9.
1986: C Gerard; Linda C McPhail; A Marfat; N P Stimler-Gerard; David A Bass; Charles E McCall
Role of protein kinases in stimulation of human polymorphonuclear leukocyte oxidative metabolism by various agonists. Differential effects of a novel protein kinase inhibitor.
The Journal of clinical investigation 1986;77(1):61-5.
1985: Charles E McCall; Linda C McPhail; W L Salzer; J D Schmitt; V Nasrallah; J Kim; Robert L Wykle; Joseph T O'Flaherty; David A Bass
Diacylglycerol activates protein kinase C and modulates oxidative metabolism in human neutrophils.
Transactions of the Association of American Physicians 1985;98():253-68.