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Teresa McQueen

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Olga Frolova; Rodrigo Jacamo; Hagop Kantarjian; Sergej Konoplev; Michael Andreeff; Juliana Maria Benito; Daniela Buglio; Steven M Kornblau; Richard Lock; Hongbo Lu; Ana Markovic; Teresa McQueen; Sherry Pierce; Yi Hua Qiu; Ismael Samudio; Wendy Schober; Elizabeth Shpall; Deborah Thomas; Marina Konopleva
Regulation of HIF-1α signaling and chemoresistance in acute lymphocytic leukemia under hypoxic conditions of the bone marrow microenvironment.
Marina Konopleva; B Korchin; Duncan H Mak; James A McCubrey; Teresa McQueen; Michele Milella; Maria R Ricciardi; Peter P Ruvolo; A Tafuri; Twee Tsao; J C Watts; P Bergamo; William G Bornmann; W Chen; Michael Andreeff
MEK inhibition enhances ABT-737-induced leukemia cell apoptosis via prevention of ERK-activated MCL-1 induction and modulation of MCL-1/BIM complex.
Kensuke Kojima; Marina Konopleva; Teresa McQueen; Naoki Shinojima; Elizabeth Shpall; Ye Chen; Xuelin Huang; Rodrigo Jacamo; Michael Andreeff
p53 activation of mesenchymal stromal cells partially abrogates microenvironment-mediated resistance to FLT3 inhibition in AML through HIF-1α-mediated down-regulation of CXCL12.

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All Publications

2012: Olga Frolova; Rodrigo Jacamo; Hagop Kantarjian; Sergej Konoplev; Michael Andreeff; Juliana Maria Benito; Daniela Buglio; Steven M Kornblau; Richard Lock; Hongbo Lu; Ana Markovic; Teresa McQueen; Sherry Pierce; Yi Hua Qiu; Ismael Samudio; Wendy Schober; Elizabeth Shpall; Deborah Thomas; Marina Konopleva
Regulation of HIF-1α signaling and chemoresistance in acute lymphocytic leukemia under hypoxic conditions of the bone marrow microenvironment.
Cancer biology & therapy 2012;13(10):858-70.
2012: Marina Konopleva; B Korchin; Duncan H Mak; James A McCubrey; Teresa McQueen; Michele Milella; Maria R Ricciardi; Peter P Ruvolo; A Tafuri; Twee Tsao; J C Watts; P Bergamo; William G Bornmann; W Chen; Michael Andreeff
MEK inhibition enhances ABT-737-induced leukemia cell apoptosis via prevention of ERK-activated MCL-1 induction and modulation of MCL-1/BIM complex.
Leukemia 2012;26(4):778-87.
2011: Kensuke Kojima; Marina Konopleva; Teresa McQueen; Naoki Shinojima; Elizabeth Shpall; Ye Chen; Xuelin Huang; Rodrigo Jacamo; Michael Andreeff
p53 activation of mesenchymal stromal cells partially abrogates microenvironment-mediated resistance to FLT3 inhibition in AML through HIF-1α-mediated down-regulation of CXCL12.
Blood 2011;118(16):4431-9.
2008: Ismael Samudio; Michael Fiegl; Teresa McQueen; Karen Clise-Dwyer; Michael Andreeff
The warburg effect in leukemia-stroma cocultures is mediated by mitochondrial uncoupling associated with uncoupling protein 2 activation.
Cancer research 2008;68(13):5198-205.
2008: W Zhang; Marina Konopleva; Vivian Ruvolo; Teresa McQueen; RL Evans; William G Bornmann; James A McCubrey; Jorge Cortes; Michael Andreeff
Sorafenib induces apoptosis of AML cells via Bim-mediated activation of the intrinsic apoptotic pathway.
Leukemia 2008;22(4):808-18.
2008: Weiguo Zhang; Marina Konopleva; Yue-Xi Shi; Teresa McQueen; David Harris; Xiaoyang Ling; Zeev Estrov; Alfonso Quintás-Cardama; Donald Small; Jorge Cortes; Michael Andreeff
Mutant FLT3: a direct target of sorafenib in acute myelogenous leukemia.
Journal of the National Cancer Institute 2008;100(3):184-98.
2007: Xiaoyang Ling; Marina Konopleva; Zhihong Zeng; Vivian Ruvolo; L Clifton Stephens; Wendy D Schober; Teresa McQueen; Martin Dietrich; Timothy L Madden; Michael Andreeff
The novel triterpenoid C-28 methyl ester of 2-cyano-3, 12-dioxoolen-1, 9-dien-28-oic acid inhibits metastatic murine breast tumor growth through inactivation of STAT3 signaling.
Cancer research 2007;67(9):4210-8.
2007: Yoko Tabe; Linhua Jin; Yuko Tsutsumi-Ishii; Yuanyuan Xu; Teresa McQueen; Waldemar Priebe; Gordon B Mills; Akimichi Ohsaka; Isao Nagaoka; Michael Andreeff; Marina Konopleva
Activation of integrin-linked kinase is a critical prosurvival pathway induced in leukemic cells by bone marrow-derived stromal cells.
Cancer research 2007;67(2):684-94.
2007: Christina L Kress; Marina Konopleva; Vanesa Martínez-García; Maryla Krajewska; Sophie Lefebvre; Marc L Hyer; Teresa McQueen; Michael Andreeff; John C Reed; Juan M Zapata
Triterpenoids display single agent anti-tumor activity in a transgenic mouse model of chronic lymphocytic leukemia and small B cell lymphoma.
PloS one 2007;2(6):e559.
2006: Marina Konopleva; Rooha Contractor; Twee Tsao; Ismael Samudio; Peter P Ruvolo; Shinichi Kitada; Xingming Deng; Dayong Zhai; Yue-Xi Shi; Thomas B Sneed; Monique Verhaegen; Maria S Soengas; Vivian Ruvolo; Teresa McQueen; Wendy D Schober; Julie C Watt; Tilahun Jiffar; Xiaoyang Ling; Frank C Marini; David Harris; Martin Dietrich; Zeev Estrov; James A McCubrey; W Stratford May; John C Reed; Michael Andreeff
Mechanisms of apoptosis sensitivity and resistance to the BH3 mimetic ABT-737 in acute myeloid leukemia.
Cancer cell 2006;10(5):375-88.
2006: Kensuke Kojima; Marina Konopleva; Teresa McQueen; Susan O'Brien; William Plunkett; Michael Andreeff
Mdm2 inhibitor Nutlin-3a induces p53-mediated apoptosis by transcription-dependent and transcription-independent mechanisms and may overcome Atm-mediated resistance to fludarabine in chronic lymphocytic leukemia.
Blood 2006;108(3):993-1000.
2006: Bing Z Carter; Duncan H Mak; Wendy D Schober; Teresa McQueen; David Harris; Zeev Estrov; Randall L Evans; Michael Andreeff
Triptolide induces caspase-dependent cell death mediated via the mitochondrial pathway in leukemic cells.
Blood 2006;108(2):630-7.
2006: Helene Pelicano; Jennifer Carew; Teresa McQueen; Michael Andreeff; William Plunkett; Michael J Keating; P Huang
Targeting Hsp90 by 17-AAG in leukemia cells: mechanisms for synergistic and antagonistic drug combinations with arsenic trioxide and Ara-C.
Leukemia 2006;20(4):610-9.
2006: Bing Z Carter; Duncan H Mak; Wendy D Schober; Maria Cabreira; Miloslav Beran; Teresa McQueen; Wenjing Chen; Michael Andreeff
Regulation of survivin expression through Bcr-Abl/MAPK cascade: targeting survivin overcomes imatinib resistance and increases imatinib sensitivity in imatinib-responsive CML cells.
Blood 2006;107(4):1555-63.
2006: Marina Konopleva; Weiguo Zhang; Yue-Xi Shi; Teresa McQueen; Twee Tsao; Maen Abdelrahim; Mark F Munsell; Mary Johansen; Dihua Yu; Timothy Madden; Stephen H Safe; Mien-Chie Hung; Michael Andreeff
Synthetic triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid induces growth arrest in HER2-overexpressing breast cancer cells.
Molecular cancer therapeutics 2006;5(2):317-28.
2005: Ismael Samudio; Marina Konopleva; Stephen Safe; Teresa McQueen; Michael Andreeff
Guggulsterones induce apoptosis and differentiation in acute myeloid leukemia: identification of isomer-specific antileukemic activities of the pregnadienedione structure.
Molecular cancer therapeutics 2005;4(12):1982-92.
2005: Marina Konopleva; Yuexi Shi; Linda Steelman; John G Shelton; Mark F Munsell; Frank C Marini; Teresa McQueen; Rooha Contractor; James A McCubrey; Michael Andreeff
Development of a conditional in vivo model to evaluate the efficacy of small molecule inhibitors for the treatment of Raf-transformed hematopoietic cells.
Cancer research 2005;65(21):9962-70.
2005: W Zhang; Teresa McQueen; Wendy D Schober; George Z Rassidakis; Michael Andreeff; Marina Konopleva
Leukotriene B4 receptor inhibitor LY293111 induces cell cycle arrest and apoptosis in human anaplastic large-cell lymphoma cells via JNK phosphorylation.
Leukemia 2005;19(11):1977-84.
2005: Kensuke Kojima; Marina Konopleva; Ismael Samudio; Masato Shikami; Maria Cabreira; Teresa McQueen; Vivian Ruvolo; Twee Tsao; Zhihong Zeng; Lyubomir T Vassilev; Michael Andreeff
MDM2 antagonists induce p53-dependent apoptosis in AML: implications for leukemia therapy.
Blood 2005;106(9):3150-9.
2005: Ismael Samudio; Marina Konopleva; Numsen Hail; Yue-Xi Shi; Teresa McQueen; Timothy Hsu; Randall Evans; Tadashi Honda; Gordon W Gribble; Michael B. Sporn; Hiram F Gilbert; Stephen Safe; Michael Andreeff
2-Cyano-3,12-dioxooleana-1,9-dien-28-imidazolide (CDDO-Im) directly targets mitochondrial glutathione to induce apoptosis in pancreatic cancer.
The Journal of biological chemistry 2005;280(43):36273-82.
2005: Maria R Ricciardi; Teresa McQueen; David Chism; Michele Milella; Elihu Estey; E Kaldjian; Judith Leopold; Marina Konopleva; Michael Andreeff
Quantitative single cell determination of ERK phosphorylation and regulation in relapsed and refractory primary acute myeloid leukemia.
Leukemia 2005;19(9):1543-9.
2004: Marina Konopleva; Twee Tsao; Zeev Estrov; Ray M Lee; Rui-Yu Wang; C Ellen Jackson; Teresa McQueen; Giuseppe Monaco; Mark F Munsell; John W Belmont; Andrew Lamb; Michael B. Sporn; Michael Andreeff
The synthetic triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid induces caspase-dependent and -independent apoptosis in acute myelogenous leukemia.
Cancer research 2004;64(21):7927-35.
2004: Marina Konopleva; Elena Elstner; Teresa McQueen; Twee Tsao; Andrey Sudarikov; Wei Hu; Wendy D Schober; Rui-Yu Wang; David Chism; Steven M Kornblau; Anas Younes; Steven J Collins; H Phillip Koeffler; Michael Andreeff
Peroxisome proliferator-activated receptor gamma and retinoid X receptor ligands are potent inducers of differentiation and apoptosis in leukemias.
Molecular cancer therapeutics 2004;3(10):1249-62.
2004: Frank Tacke; Frank C Marini; Shourong Zhao; Teresa McQueen; Marina Konopleva; Peter P Ruvolo; Shi-Xue Hu; Hong-Ji Xu; Michael Andreeff
Expression of inducible Bcl-X(S) in myeloid leukemia: compensatory upregulation of Bcl-X(L) and Bcl-2 prevents apoptosis and chemosensitization.
Cancer biology & therapy 2004;3(3):340-7.
2004: Yoko Tabe; Marina Konopleva; Mark F Munsell; Frank C Marini; Claudia Zompetta; Teresa McQueen; Twee Tsao; Shourong Zhao; Sherry Pierce; Jun Igari; Elihu H Estey; Michael Andreeff
PML-RARalpha is associated with leptin-receptor induction: the role of mesenchymal stem cell-derived adipocytes in APL cell survival.
Blood 2004;103(5):1815-22.
2004: Michael Andreeff; Michele Milella; Bing Z Carter; Yoko Tabe; Maria R Ricciardi; Thomas B Sneed; Peter P Ruvolo; Rooha Contractor; Twee Tsao; Wendy D Schober; Randall Evans; Teresa McQueen; Zhihong Zeng; Steven M Kornblau; James A McCubrey; Elihu Estey; Gordon B Mills; John C Reed; Marina Konopleva
Targeted therapy of AML new concepts.
Annals of hematology 2004;83 Suppl 1():S51-3.
2003: Bing Z Carter; Michele Milella; Twee Tsao; Teresa McQueen; Wendy D Schober; Wei Hu; Nicholas Dean; Linda Steelman; James A McCubrey; Michael Andreeff
Regulation and targeting of antiapoptotic XIAP in acute myeloid leukemia.
Leukemia 2003;17(11):2081-9.
2003: Helene Lapillonne; Marina Konopleva; Twee Tsao; David Gold; Teresa McQueen; Robert L Sutherland; Timothy Madden; Michael Andreeff
Activation of peroxisome proliferator-activated receptor gamma by a novel synthetic triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid induces growth arrest and apoptosis in breast cancer cells.
Cancer research 2003;63(18):5926-39.
1997: Kapil Mehta; P Pantazis; Teresa McQueen; Bharat B Aggarwal
Antiproliferative effect of curcumin (diferuloylmethane) against human breast tumor cell lines.
Anti-cancer drugs 1997;8(5):470-81.
1997: Kapil Mehta; Teresa McQueen; Taghi Manshouri; Michael Andreeff; S Collins; Maher Albitar
Involvement of retinoic acid receptor-alpha-mediated signaling pathway in induction of CD38 cell-surface antigen.
Blood 1997;89(10):3607-14.
1996: Kapil Mehta; Teresa McQueen; N Neamati; S Collins; Michael Andreeff
Activation of retinoid receptors RAR alpha and RXR alpha induces differentiation and apoptosis, respectively, in HL-60 cells.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1996;7(2):179-86.
1995: R N Singh; Teresa McQueen; Kapil Mehta
Detection of the amine acceptor protein substrates of transglutaminase with 5-(biotinamido) pentylamine.
Analytical biochemistry 1995;231(1):261-3.
1994: Kapil Mehta; T Sadeghi; Teresa McQueen; Gabriel Lopez-Berestein
Liposome encapsulation circumvents the hepatic clearance mechanisms of all-trans-retinoic acid.
Leukemia research 1994;18(8):587-96.
1994: RT Mehta; Teresa McQueen; Afsaneh Keyhani; G López-Berestein
Phagocyte transport as mechanism for enhanced therapeutic activity of liposomal amphotericin B.
Chemotherapy 1994;40(4):256-64.
1994: Johannes Drach; Teresa McQueen; H Engel; Michael Andreeff; K A Robertson; Steven J Collins; F Malavasi; Kapil Mehta
Retinoic acid-induced expression of CD38 antigen in myeloid cells is mediated through retinoic acid receptor-alpha.
Cancer research 1994;54(7):1746-52.
1993: RT Mehta; Afsaneh Keyhani; Teresa McQueen; B Rosenbaum; Kenneth V I Rolston; Jeffrey J Tarrand
In vitro activities of free and liposomal drugs against Mycobacterium avium-M. intracellulare complex and M. tuberculosis.
Antimicrobial agents and chemotherapy 1993;37(12):2584-7.
1993: Johannes Drach; Gabriel Lopez-Berestein; Teresa McQueen; Michael Andreeff; Kapil Mehta
Induction of differentiation in myeloid leukemia cell lines and acute promyelocytic leukemia cells by liposomal all-trans-retinoic acid.
Cancer research 1993;53(9):2100-4.
1991: RT Mehta; Teresa McQueen; Afsaneh Keyhani; Gabriel Lopez-Berestein
Liposomal hamycin: reduced toxicity and improved antifungal efficacy in vitro and in vivo.
The Journal of infectious diseases 1991;164(5):1003-6.
1991: Peter Pritchard; K Vadiei; D R Luke; Afsaneh Keyhani; R A White; Teresa McQueen; R Mehta; Gabriel Lopez-Berestein
Antifungal activity of HWA-138 and amphotericin B in experimental systemic candidiasis.
Antimicrobial agents and chemotherapy 1991;35(10):2046-8.
1990: D R Luke; Peter Pritchard; Teresa McQueen; Gabriel Lopez-Berestein
Enhancement of the treatment of experimental candidiasis with vascular decongestants.
The Journal of infectious diseases 1990;162(1):211-4.
1987: RT Mehta; R L Hopfer; Teresa McQueen; Rudy L Juliano; Gabriel Lopez-Berestein
Toxicity and therapeutic effects in mice of liposome-encapsulated nystatin for systemic fungal infections.
Antimicrobial agents and chemotherapy 1987;31(12):1901-3.