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Daniel Medina

Research Profile

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Genes, p53

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TOP 3
Abhijit Mazumdar; Daniel Medina; Yun Zhang; Reid P Bissonnette; David E Edwards; Jamal L Hill; Frances S Kittrell; Powel H Brown
The combination of tamoxifen and the rexinoid LG100268 prevents ER-positive and ER-negative mammary tumors in p53-null mammary gland mice.
Daniel Medina; David G Edwards; Frances S Kittrell; Sangjun Lee; D Craig Allred
Intra-mammary ductal transplantation: a tool to study premalignant progression.
Michael Lewis; Homer C Adams; John D Landua; Daniel Medina
A mystery wrapped in an enigma: Matrigel enhancement of mammary cell growth and morphogenesis.

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All Publications

2012: Abhijit Mazumdar; Daniel Medina; Yun Zhang; Reid P Bissonnette; David E Edwards; Jamal L Hill; Frances S Kittrell; Powel H Brown
The combination of tamoxifen and the rexinoid LG100268 prevents ER-positive and ER-negative mammary tumors in p53-null mammary gland mice.
Cancer prevention research (Philadelphia, Pa.) 2012;5(10):1195-202.
2012: Daniel Medina; David G Edwards; Frances S Kittrell; Sangjun Lee; D Craig Allred
Intra-mammary ductal transplantation: a tool to study premalignant progression.
Journal of mammary gland biology and neoplasia 2012;17(2):131-3.
2012: Michael Lewis; Homer C Adams; John D Landua; Daniel Medina
A mystery wrapped in an enigma: Matrigel enhancement of mammary cell growth and morphogenesis.
Journal of mammary gland biology and neoplasia 2012;17(2):99-101.
2012: Jason I Herschkowitz; Susan G Hilsenbeck; Jana Knezevic; Daniel Medina; George Murrow; Charles M Perou; Melissa A Troester; Jerry Usary; Mei Zhang; Wei Zhao; David Darr; David Edwards; Stephanie B Greene; Jeffrey M Rosen
Comparative oncogenomics identifies breast tumors enriched in functional tumor-initiating cells.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(8):2778-83.
2010: Daniel Medina
Of mice and women: A short history of mouse mammary cancer research with an emphasis on the paradigms inspired by the transplantation method.
Cold Spring Harbor perspectives in biology 2010;2(10):a004523.
2010: Haoheng Yan; Anneke C Blackburn; S Christine McLary; Luwei Tao; Amy L Roberts; Elizabeth A Xavier; Ellen S Dickinson; Jae Hong Seo; Richard B Arenas; Christopher N Otis; Qing J Cao; Rebecca G Lawlor; Barbara A Osborne; Frances S Kittrell; Daniel Medina; D Joseph Jerry
Pathways contributing to development of spontaneous mammary tumors in BALB/c-Trp53+/- mice.
The American journal of pathology 2010;176(3):1421-32.
2009: Matthew H Herynk; Michael Lewis; Torsten A Hopp; Daniel Medina; A Corona-Rodriguez; Yukun Cui; A R Beyer; Suzanne A W Fuqua
Accelerated mammary maturation and differentiation, and delayed MMTVneu-induced tumorigenesis of K303R mutant ERalpha transgenic mice.
Oncogene 2009;28(36):3177-87.
2009: Daniel Medina; Frances S Kittrell; Jamal Hill; Yun Zhang; Susan G Hilsenbeck; Reid Bissonette; Powel H Brown
Prevention of tumorigenesis in p53-null mammary epithelium by rexinoid bexarotene, tyrosine kinase inhibitor gefitinib, and celecoxib.
Cancer prevention research (Philadelphia, Pa.) 2009;2(2):168-74.
2009: Benny Abraham Kaipparettu; Klaudia M Dobrzycka; Ora Britton; Adrian V Lee; Alan J Herron; Yi Li; Michael Lewis; Daniel Medina; Steffi Oesterreich
Scaffold Attachment Factor B1 (SAFB1) heterozygosity does not influence Wnt-1 or DMBA-induced tumorigenesis.
Molecular cancer 2009;8():15.
2008: Nenggang Zhang; Gouquing Ge; Rene Meyer; Sumita Sethi; Dipanjan Basu; Subhashree Pradhan; Yi-Jue Zhao; Xiao-Nan Li; Wei-Wen Cai; Adel K El-Naggar; Veerabhadran Baladandayuthapani; Frances S Kittrell; Pulivarthi H Rao; Daniel Medina; Debananda Pati
Overexpression of Separase induces aneuploidy and mammary tumorigenesis.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(35):13033-8.
2008: Daniel Medina
Premalignant and malignant mammary lesions induced by MMTV and chemical carcinogens.
Journal of mammary gland biology and neoplasia 2008;13(3):271-7.
2008: Mei Zhang; Fariba Behbod; Rachel L Atkinson; Melissa D Landis; Frances S Kittrell; David Edwards; Daniel Medina; Anna Tsimelzon; Susan G Hilsenbeck; Jeffrey E Green; Aleksandra M Michalowska; Jeffrey M Rosen
Identification of tumor-initiating cells in a p53-null mouse model of breast cancer.
Cancer research 2008;68(12):4674-82.
2008: Catherine Gatza; Melissa Dumble; Frances S Kittrell; David G Edwards; Robert K Dearth; Adrian V Lee; Jianming Xu; Daniel Medina; Lawrence A Donehower
Altered mammary gland development in the p53+/m mouse, a model of accelerated aging.
Developmental biology 2008;313(1):130-41.
2008: Zhigang Li; Christian Schem; Yihui H Shi; Daniel Medina; Ming Zhang
Increased COX2 expression enhances tumor-induced osteoclastic lesions in breast cancer bone metastasis.
Clinical & experimental metastasis 2008;25(4):389-400.
2007: Christian R Loehberg; Tiia Thompson; Michael B Kastan; Kirsteen H Maclean; Dean G Edwards; Frances S Kittrell; Daniel Medina; Orla M Conneely; Bert W O'Malley
Ataxia telangiectasia-mutated and p53 are potential mediators of chloroquine-induced resistance to mammary carcinogenesis.
Cancer research 2007;67(24):12026-33.
2007: Joanna G Koch; Xiangjun Gu; Younghun Han; Adel K El-Naggar; Melissa V Olson; Daniel Medina; D Joseph Jerry; Anneke C Blackburn; Gary Peltz; Christopher I Amos; Guillermina Lozano
Mammary tumor modifiers in BALB/cJ mice heterozygous for p53.
Mammalian genome : official journal of the International Mammalian Genome Society 2007;18(5):300-9.
2007: Thea M Goepfert; Myrthala Moreno-Smith; David G Edwards; Sen Pathak; Daniel Medina; William R Brinkley
Loss of chromosomal integrity drives rat mammary tumorigenesis.
International journal of cancer. Journal international du cancer 2007;120(5):985-94.
2007: Daniel Medina; Frances S Kittrell; Anna Tsimelzon; S A W Fuqua
Inhibition of mammary tumorigenesis by estrogen and progesterone in genetically engineered mice.
Ernst Schering Foundation symposium proceedings 2007;(1):109-26.
2007: Daniel Medina
Chemical carcinogenesis of rat and mouse mammary glands.
Breast disease 2007;28():63-8.
2006: Rui-An Wang; H Zhang; Seetharaman Balasenthil; Daniel Medina; Rakesh Kumar
PAK1 hyperactivation is sufficient for mammary gland tumor formation.
Oncogene 2006;25(20):2931-6.
2005: Daniel Medina
Mammary developmental fate and breast cancer risk.
Endocrine-related cancer 2005;12(3):483-95.
2005: Shao-Qing Kuang; Lan Liao; Shu Wang; Daniel Medina; Bert W O'Malley; Jianming Xu
Mice lacking the amplified in breast cancer 1/steroid receptor coactivator-3 are resistant to chemical carcinogen-induced mammary tumorigenesis.
Cancer research 2005;65(17):7993-8002.
2005: Daniel Medina; Frances S Kittrell; Jamal Hill; Anne Shepard; Gudmundur Thordarson; Powel Brown
Tamoxifen inhibition of estrogen receptor-alpha-negative mouse mammary tumorigenesis.
Cancer research 2005;65(8):3493-6.
2005: Daniel Medina; Frances S Kittrell
Stroma is not a major target in DMBA-mediated tumorigenesis of mouse mammary preneoplasia.
Journal of cell science 2005;118(Pt 1):123-7.
2004: Debananda Pati; Bassem R Haddad; Albert Haegele; Henry Thompson; Frances S Kittrell; Anne Shepard; Cristina Montagna; Nenggang Zhang; Gouqing Ge; Subhendu Otta; Maureen McCarthy; Robert L Ullrich; Daniel Medina
Hormone-induced chromosomal instability in p53-null mammary epithelium.
Cancer research 2004;64(16):5608-16.
2004: Yijun Yi; Anne Shepard; Frances S Kittrell; Biserka Mulac-Jericevic; Daniel Medina; Thenaa K Said
p19ARF determines the balance between normal cell proliferation rate and apoptosis during mammary gland development.
Molecular biology of the cell 2004;15(5):2302-11.
2004: Daniel Medina
Stromal fibroblasts influence human mammary epithelial cell morphogenesis.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(14):4723-4.
2004: D Craig Allred; Powel Brown; Daniel Medina
The origins of estrogen receptor alpha-positive and estrogen receptor alpha-negative human breast cancer.
Breast cancer research : BCR 2004;6(6):240-5.
2004: Thenaa K Said; Daniel Medina
Cell cycle genes in a mouse mammary hyperplasia model.
Journal of mammary gland biology and neoplasia 2004;9(1):81-93.
2004: Daniel Medina
Breast cancer: the protective effect of pregnancy.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(1 Pt 2):380S-4S.
2003: Daniel Medina; Frances S Kittrell
p53 function is required for hormone-mediated protection of mouse mammary tumorigenesis.
Cancer research 2003;63(19):6140-3.
2003: Daniel Medina; Frances S Kittrell; Anne Shepard; Alejandro Contreras; Jeffrey M Rosen; John Lydon
Hormone dependence in premalignant mammary progression.
Cancer research 2003;63(5):1067-72.
2003: Heidi Y Shi; Weiguo Zhang; Rong Liang; Frances S Kittrell; Nancy Smyth Templeton; Daniel Medina; Ming Zhang
Modeling human breast cancer metastasis in mice: maspin as a paradigm.
Histology and histopathology 2003;18(1):201-6.
2002: Gu Kong; Steven S Chua; Yi Yijun; Frances S Kittrell; Ricardo C Moraes; Daniel Medina; Thenaa K Said
Functional analysis of cyclin D2 and p27(Kip1) in cyclin D2 transgenic mouse mammary gland during development.
Oncogene 2002;21(47):7214-25.
2002: Daniel Medina
Biological and molecular characteristics of the premalignant mouse mammary gland.
Biochimica et biophysica acta 2002;1603(1):1-9.
2002: Thea M Goepfert; Yetunde E Adigun; Ling Zhong; Jason Gay; Daniel Medina; William R Brinkley
Centrosome amplification and overexpression of aurora A are early events in rat mammary carcinogenesis.
Cancer research 2002;62(14):4115-22.
2002: Daniel Medina; Frances S Kittrell; Anne Shepard; L Clifton Stephens; Cheng Jiang; Junxuan Lu; D Craig Allred; Maureen McCarthy; Robert L Ullrich
Biological and genetic properties of the p53 null preneoplastic mammary epithelium.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002;16(8):881-3.
2002: Lakshmi Sivaraman; Jason Gay; Susan G Hilsenbeck; Harold Shine; Orla M Conneely; Daniel Medina; Bert W O'Malley
Effect of selective ablation of proliferating mammary epithelial cells on MNU induced rat mammary tumorigenesis.
Breast cancer research and treatment 2002;73(1):75-83.
2002: Lakshmi Sivaraman; Daniel Medina
Hormone-induced protection against breast cancer.
Journal of mammary gland biology and neoplasia 2002;7(1):77-92.
2002: Daniel Medina; Robert Ullrich; Raymond Meyn; Roger Wiseman; Lawrence A Donehower
Environmental carcinogens and p53 tumor-suppressor gene interactions in a transgenic mouse model for mammary carcinogenesis.
Environmental and molecular mutagenesis 2002;39(2-3):178-83.
2001: Daniel Medina; Lakshmi Sivaraman; Susan G Hilsenbeck; Orla M Conneely; Melanie R Ginger; J Rosen; B W Omalle
Mechanisms of hormonal prevention of breast cancer.
Annals of the New York Academy of Sciences 2001;952():23-35.
2001: C. Annette Hollmann; Frances S Kittrell; Daniel Medina; Janet S Butel
Wnt-1 and int-2 mammary oncogene effects on the beta-catenin pathway in immortalized mouse mammary epithelial cells are not sufficient for tumorigenesis.
Oncogene 2001;20(52):7645-57.
2001: Lakshmi Sivaraman; Orla M Conneely; Daniel Medina; Bert W O'Malley
p53 is a potential mediator of pregnancy and hormone-induced resistance to mammary carcinogenesis.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(22):12379-84.
2001: Lakshmi Sivaraman; Susan G Hilsenbeck; Ling Zhong; Jason Gay; Orla M Conneely; Daniel Medina; Bert W O'Malley
Early exposure of the rat mammary gland to estrogen and progesterone blocks co-localization of estrogen receptor expression and proliferation.
The Journal of endocrinology 2001;171(1):75-83.
2001: Heidi Y Shi; Weiguo Zhang; Rong Liang; S Abraham; Frances S Kittrell; Daniel Medina; Ming Zhang
Blocking tumor growth, invasion, and metastasis by maspin in a syngeneic breast cancer model.
Cancer research 2001;61(18):6945-51.
2001: Daniel Medina; Leif Peterson; Ricardo C Moraes; Jason Gay
Short-term exposure to estrogen and progesterone induces partial protection against N-nitroso-N-methylurea-induced mammary tumorigenesis in Wistar--Furth rats.
Cancer letters 2001;169(1):1-6.
2001: Thenaa K Said; Ricardo C Moraes; U Singh; Frances S Kittrell; Daniel Medina
Cyclin-dependent kinase (cdk) inhibitors/cdk4/cdk2 complexes in early stages of mouse mammary preneoplasia.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 2001;12(6):285-95.
2001: Raghu Sinha; Emmanual Unni; Howard E Ganther; Daniel Medina
Methylseleninic acid, a potent growth inhibitor of synchronized mouse mammary epithelial tumor cells in vitro.
Biochemical pharmacology 2001;61(3):311-7.
2001: Daniel Medina; H Thompson; Howard E Ganther; C Ip
Se-methylselenocysteine: a new compound for chemoprevention of breast cancer.
Nutrition and cancer 2001;40(1):12-7.
2001: T K Said; R C Moraes; Raghu Sinha; Daniel Medina
Mechanisms of suberoylanilide hydroxamic acid inhibition of mammary cell growth.
Breast cancer research : BCR 2001;3(2):122-33.
2001: Cynthia A Zahnow; Robert Cardiff; Rodolfo Laucirica; Daniel Medina; Jeffrey M Rosen
A role for CCAAT/enhancer binding protein beta-liver-enriched inhibitory protein in mammary epithelial cell proliferation.
Cancer research 2001;61(1):261-9.
2000: Charlotte Kuperwasser; G D Hurlbut; Frances S Kittrell; Ellen S Dickinson; R Laucirica; Daniel Medina; Stephen P Naber; D Joseph Jerry
Development of spontaneous mammary tumors in BALB/c p53 heterozygous mice. A model for Li-Fraumeni syndrome.
The American journal of pathology 2000;157(6):2151-9.
2000: M Mixon; Frances S Kittrell; Daniel Medina
Expression of Brca1 and splice variant Brca1delta11 RNA levels in mouse mammary gland during normal development and tumorigenesis.
Oncogene 2000;19(46):5237-43.
2000: Thea M Goepfert; Maureen McCarthy; Frances S Kittrell; C Stephens; Robert L Ullrich; Bill R Brinkley; Daniel Medina
Progesterone facilitates chromosome instability (aneuploidy) in p53 null normal mammary epithelial cells.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2000;14(14):2221-9.
2000: D C Allred; Daniel Medina
Introduction: models of premalignant breast disease.
Journal of mammary gland biology and neoplasia 2000;5(4):339-40.
2000: Daniel Medina
The preneoplastic phenotype in murine mammary tumorigenesis.
Journal of mammary gland biology and neoplasia 2000;5(4):393-407.
2000: Lakshmi Sivaraman; Zafar Nawaz; Daniel Medina; Orla M Conneely; Bert W O'Malley
The dual function steroid receptor coactivator/ubiquitin protein-ligase integrator E6-AP is overexpressed in mouse mammary tumorigenesis.
Breast cancer research and treatment 2000;62(3):185-95.
2000: D Joseph Jerry; Frances S Kittrell; Charlotte Kuperwasser; R Laucirica; Ellen S Dickinson; P J Bonilla; Janet S Butel; Daniel Medina
A mammary-specific model demonstrates the role of the p53 tumor suppressor gene in tumor development.
Oncogene 2000;19(8):1052-8.
1999: Raghu Sinha; SC Kiley; J X Lu; H J Thompson; Ricardo C Moraes; S Jaken; Daniel Medina
Effects of methylselenocysteine on PKC activity, cdk2 phosphorylation and gadd gene expression in synchronized mouse mammary epithelial tumor cells.
Cancer letters 1999;146(2):135-45.
1999: KL Murphy; Frances S Kittrell; Jason Gay; richard jäger; Daniel Medina; Jeffrey M Rosen
Bcl-2 expression delays mammary tumor development in dimethylbenz(a)anthracene-treated transgenic mice.
Oncogene 1999;18(47):6597-604.
1999: J P Lydon; Gouqing Ge; Frances S Kittrell; Daniel Medina; Bert W O'Malley
Murine mammary gland carcinogenesis is critically dependent on progesterone receptor function.
Cancer research 1999;59(17):4276-84.
1999: Sharon Bonnette; Frances S Kittrell; L Clifton Stephens; R E Meyn; Daniel Medina
Interactions of apoptosis, proliferation and host age in the regression of the mouse mammary preneoplasia, TM3, carrying an unusual mutation in p53.
Carcinogenesis 1999;20(9):1715-20.
1999: Elmar Stickeler; Frances S Kittrell; Daniel Medina; Susan M Berget
Stage-specific changes in SR splicing factors and alternative splicing in mammary tumorigenesis.
Oncogene 1999;18(24):3574-82.
1999: Daniel Medina; G H Smith
Chemical carcinogen-induced tumorigenesis in parous, involuted mouse mammary glands.
Journal of the National Cancer Institute 1999;91(11):967-9.
1999: J Pinkas; Stephen P Naber; Janet S Butel; Daniel Medina; D Joseph Jerry
Expression of MDM2 during mammary tumorigenesis.
International journal of cancer. Journal international du cancer 1999;81(2):292-8.
1999: J M Jones; XS Cui; Daniel Medina; Lawrence A Donehower
Heterozygosity of p21WAF1/CIP1 enhances tumor cell proliferation and cyclin D1-associated kinase activity in a murine mammary cancer model.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1999;10(4):213-22.
1998: Allan Bradley; Daniel Medina
Introduction: BRCA1 and BRCA2 in mammary gland development and tumorigenesis.
Journal of mammary gland biology and neoplasia 1998;3(4):363-4.
1998: Denise J Schwahn; Daniel Medina
p96, a MAPK-related protein, is consistently downregulated during mouse mammary carcinogenesis.
Oncogene 1998;17(9):1173-8.
1998: Lakshmi Sivaraman; L Clifton Stephens; Barry M Markaverich; J A Clark; S Krnacik; Orla M Conneely; Bert W O'Malley; Daniel Medina
Hormone-induced refractoriness to mammary carcinogenesis in Wistar-Furth rats.
Carcinogenesis 1998;19(9):1573-81.
1998: Xiao-Jing Wang; DA Greenhalgh; A Jiang; D He; Ling Zhong; Daniel Medina; Bill R Brinkley; Dennis R Roop
Expression of a p53 mutant in the epidermis of transgenic mice accelerates chemical carcinogenesis.
Oncogene 1998;17(1):35-45.
1998: Daniel Medina; L Clifton Stephens; P J Bonilla; C. Annette Hollmann; Denise J Schwahn; Charlotte Kuperwasser; D Joseph Jerry; Janet S Butel; R E Meyn
Radiation-induced tumorigenesis in preneoplastic mouse mammary glands in vivo: significance of p53 status and apoptosis.
Molecular carcinogenesis 1998;22(3):199-207.
1998: Thenaa K Said; Daniel Medina
Interaction of retinoblastoma protein and D cyclins during cell-growth inhibition by hexamethylenebisacetamide in TM2H mouse epithelial cells.
Molecular carcinogenesis 1998;22(2):128-43.
1998: Meei-Huey Jeng; C Kao; Lakshmi Sivaraman; S Krnacik; Leland W K Chung; Daniel Medina; Orla M Conneely; Bert W O'Malley
Reconstitution of estrogen-dependent transcriptional activation of an adenoviral target gene in select regions of the rat mammary gland.
Endocrinology 1998;139(6):2916-25.
1998: B Li; KL Murphy; Rodolfo Laucirica; Frances S Kittrell; Daniel Medina; Jeffrey M Rosen
A transgenic mouse model for mammary carcinogenesis.
Oncogene 1998;16(8):997-1007.
1997: T K Said; Orla M Conneely; Daniel Medina; Bert W O'Malley; John P Lydon
Progesterone, in addition to estrogen, induces cyclin D1 expression in the murine mammary epithelial cell, in vivo.
Endocrinology 1997;138(9):3933-9.
1997: Raghu Sinha; Daniel Medina
Inhibition of cdk2 kinase activity by methylselenocysteine in synchronized mouse mammary epithelial tumor cells.
Carcinogenesis 1997;18(8):1541-7.
1997: J M Jones; Laura D Attardi; L A Godley; Rodolfo Laucirica; Daniel Medina; Tyler Jacks; Harold Varmus; Lawrence A Donehower
Absence of p53 in a mouse mammary tumor model promotes tumor cell proliferation without affecting apoptosis.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1997;8(8):829-38.
1996: T K Said; S Bonnette; Daniel Medina
Immortal, non-tumourigenic mouse mammary outgrowths express high levels of cyclin B1 and activation of cyclin B1/cdc2 kinase.
Cell proliferation 1996;29(11):623-39.
1996: Raghu Sinha; T K Said; Daniel Medina
Organic and inorganic selenium compounds inhibit mouse mammary cell growth in vitro by different cellular pathways.
Cancer letters 1996;107(2):277-84.
1996: Brian Raught; Anne-Claude Gingras; A James; Daniel Medina; Nahum Sonenberg; Jeffrey M Rosen
Expression of a translationally regulated, dominant-negative CCAAT/enhancer-binding protein beta isoform and up-regulation of the eukaryotic translation initiation factor 2alpha are correlated with neoplastic transformation of mammary epithelial cells.
Cancer research 1996;56(19):4382-6.
1996: Betty L Slagle; T H Lee; Daniel Medina; M J Finegold; Janet S Butel
Increased sensitivity to the hepatocarcinogen diethylnitrosamine in transgenic mice carrying the hepatitis B virus X gene.
Molecular carcinogenesis 1996;15(4):261-9.
1996: Lawrence A Donehower; L A Godley; C M Aldaz; R Pyle; Y P Shi; D Pinkel; J Gray; Allan Bradley; Daniel Medina; Harold Varmus
The role of p53 loss in genomic instability and tumor progression in a murine mammary cancer model.
Progress in clinical and biological research 1996;395():1-11.
1996: Daniel Medina
Preneoplasia in mammary tumorigenesis.
Cancer treatment and research 1996;83():37-69.
1995: T K Said; L Luo; Daniel Medina
Mouse mammary hyperplasias and neoplasias exhibit different patterns of cyclins D1 and D2 binding to cdk4.
Carcinogenesis 1995;16(10):2507-13.
1995: B Li; Frances S Kittrell; Daniel Medina; Jeffrey M Rosen
Delay of dimethylbenz[a]anthracene-induced mammary tumorigenesis in transgenic mice by apoptosis induced by an unusual mutant p53 protein.
Molecular carcinogenesis 1995;14(2):75-83.
1995: R Mukhopadhyay; Daniel Medina; Janet S Butel
Expression of the mouse mammary tumor virus long terminal repeat open reading frame promotes tumorigenic potential of hyperplastic mouse mammary epithelial cells.
Virology 1995;211(1):74-93.
1995: Norman M Greenberg; F DeMayo; M J Finegold; Daniel Medina; W D Tilley; J O Aspinall; G R Cunha; A A Donjacour; R J Matusik; Jeffrey M Rosen
Prostate cancer in a transgenic mouse.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(8):3439-43.
1995: T K Said; Daniel Medina
Tyrosine phosphorylation in mouse mammary hyperplasias.
Carcinogenesis 1995;16(4):923-30.
1995: T K Said; Daniel Medina
Cell cyclins and cyclin-dependent kinase activities in mouse mammary tumor development.
Carcinogenesis 1995;16(4):823-30.
1995: Lawrence A Donehower; L A Godley; C M Aldaz; R Pyle; Y P Shi; D Pinkel; J Gray; Allan Bradley; Daniel Medina; Harold Varmus
Deficiency of p53 accelerates mammary tumorigenesis in Wnt-1 transgenic mice and promotes chromosomal instability.
Genes & development 1995;9(7):882-95.
1994: B Li; N Greenberg; L C Stephens; R Meyn; Daniel Medina; Jeffrey M Rosen
Preferential overexpression of a 172Arg-->Leu mutant p53 in the mammary gland of transgenic mice results in altered lobuloalveolar development.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1994;5(7):711-21.
1994: D Joseph Jerry; Janet S Butel; Lawrence A Donehower; E J Paulson; C Cochran; Roger W Wiseman; Daniel Medina
Infrequent p53 mutations in 7,12-dimethylbenz[a]anthracene-induced mammary tumors in BALB/c and p53 hemizygous mice.
Molecular carcinogenesis 1994;9(3):175-83.
1993: Michelle A Ozbun; Daniel Medina; Janet S Butel
p53 mutations in mouse mammary epithelial cells: instability in culture and discordant selection of mutations in vitro versus in vivo.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1993;4(10):811-9.
1993: Raghu Sinha; M P Bansal; H Ganther; Daniel Medina
Significance of selenium-labeled proteins for selenium's chemopreventive functions.
Carcinogenesis 1993;14(9):1895-900.
1993: D Joseph Jerry; Michelle A Ozbun; Frances S Kittrell; D P Lane; Daniel Medina; Janet S Butel
Mutations in p53 are frequent in the preneoplastic stage of mouse mammary tumor development.
Cancer research 1993;53(14):3374-81.
1993: Michelle A Ozbun; D Joseph Jerry; Frances S Kittrell; Daniel Medina; Janet S Butel
p53 mutations selected in vivo when mouse mammary epithelial cells form hyperplastic outgrowths are not necessary for establishment of mammary cell lines in vitro.
Cancer research 1993;53(7):1646-52.
1993: M P Bansal; Daniel Medina
Expression of fatty acid-binding proteins in the developing mouse mammary gland.
Biochemical and biophysical research communications 1993;191(1):61-9.
1993: Daniel Medina; Frances S Kittrell; C J Oborn; M Schwartz
Growth factor dependency and gene expression in preneoplastic mouse mammary epithelial cells.
Cancer research 1993;53(3):668-74.
1993: Daniel Medina; Frances S Kittrell; Y J Liu; M Schwartz
Morphological and functional properties of TM preneoplastic mammary outgrowths.
Cancer research 1993;53(3):663-7.
1993: Daniel Medina; Frances S Kittrell
Immortalization phenotype dissociated from the preneoplastic phenotype in mouse mammary epithelial outgrowths in vivo.
Carcinogenesis 1993;14(1):25-8.
1993: L Zhang; Daniel Medina
Gene expression screening for specific genes associated with mouse mammary tumor development.
Molecular carcinogenesis 1993;8(2):123-6.
1992: M S Schwartz; G H Smith; Daniel Medina
The effect of parity, tumor latency and transplantation on the activation of int loci in MMTV-induced, transplanted C3H mammary pre-neoplasias and their tumors.
International journal of cancer. Journal international du cancer 1992;51(5):805-11.
1992: Barry M Markaverich; T H Schauweker; R R Gregory; M Varma; F S Kittrell; Daniel Medina; R S Varma
Nuclear type II sites and malignant cell proliferation: inhibition by 2,6-bis-benzylidenecyclohexanones.
Cancer research 1992;52(9):2482-8.
1992: Frances S Kittrell; C J Oborn; Daniel Medina
Development of mammary preneoplasias in vivo from mouse mammary epithelial cell lines in vitro.
Cancer research 1992;52(7):1924-32.
1991: M P Bansal; C Ip; Daniel Medina
Levels and 75Se-labeling of specific proteins as a consequence of dietary selenium concentration in mice and rats.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) 1991;196(2):147-54.
1990: M P Bansal; T Mukhopadhyay; J Scott; Richard G Cook; R Mukhopadhyay; Daniel Medina
DNA sequencing of a mouse liver protein that binds selenium: implications for selenium's mechanism of action in cancer prevention.
Carcinogenesis 1990;11(11):2071-3.
1990: E M Durban; J E Knepper; Daniel Medina; Janet S Butel
Influence of mammary cell differentiation on the expression of proteins encoded by endogenous BALB/c mouse mammary tumor virus genes.
Virus research 1990;16(3):307-23.
1990: Barry M Markaverich; R R Gregory; M Alejandro; F S Kittrell; Daniel Medina; J H Clark; M Varma; R S Varma
Methyl p-hydroxyphenyllactate and nuclear type II binding sites in malignant cells: metabolic fate and mammary tumor growth.
Cancer research 1990;50(5):1470-8.
1989: M P Bansal; Richard G Cook; K G Danielson; Daniel Medina
A 14-kilodalton selenium-binding protein in mouse liver is fatty acid-binding protein.
The Journal of biological chemistry 1989;264(23):13780-4.
1989: K G Danielson; J E Knepper; Frances S Kittrell; Janet S Butel; Daniel Medina; E M Durban
Clonal populations of the mouse mammary cell line, COMMA-D, which retain capability of morphogenesis in vivo.
In vitro cellular & developmental biology : journal of the Tissue Culture Association 1989;25(6):535-43.
1989: D G Morrison; M P Bansal; Frances S Kittrell; Daniel Medina
Distribution of selenium-binding proteins in different tissues of the mouse and rat.
In vivo (Athens, Greece) 1989;3(3):167-72.
1989: M P Bansal; C J Oborn; K G Danielson; Daniel Medina
Evidence for two selenium-binding proteins distinct from glutathione peroxidase in mouse liver.
Carcinogenesis 1989;10(3):541-6.
1989: D G Morrison; Daniel Medina
Time course of selenite metabolism in confluent cultures of mouse mammary epithelial cells.
Chemico-biological interactions 1989;71(2-3):177-86.
1989: J E Knepper; Frances S Kittrell; Daniel Medina; Janet S Butel
Spontaneous progression of hyperplastic outgrowths of the D1 lineage to mammary tumors: expression of mouse mammary tumor virus and cellular proto-oncogenes.
Molecular carcinogenesis 1989;1(4):229-38.
1988: D G Morrison; C J Oborn; Daniel Medina
Selenite distribution in log and confluent growth phase murine mammary epithelial cells.
Cancer letters 1988;43(3):227-36.
1988: D G Morrison; Daniel Medina
Distinguishing features of cytotoxic and pharmacological effects of selenite in murine mammary epithelial cells in vitro.
Toxicology letters 1988;44(3):307-14.
1988: D G Morrison; M K Dishart; Daniel Medina
Intracellular 58-kd selenoprotein levels correlate with inhibition of DNA synthesis in mammary epithelial cells.
Carcinogenesis 1988;9(10):1801-10.
1988: D G Morrison; M K Dishart; Daniel Medina
Serine and methionine enhancement of selenite inhibition of DNA synthesis in a mouse mammary epithelial cell line.
Carcinogenesis 1988;9(10):1811-5.
1988: Daniel Medina
The preneoplastic state in mouse mammary tumorigenesis.
Carcinogenesis 1988;9(7):1113-9.
1988: S M Campbell; M M Taha; Daniel Medina; Jeffrey M Rosen
A clonal derivative of mammary epithelial cell line COMMA-D retains stem cell characteristics of unique morphological and functional heterogeneity.
Experimental cell research 1988;177(1):109-21.
1988: D G Morrison; D F Pauly; R C Berdan; M K Dishart; D S Turner; C J Oborn; Daniel Medina
Mitochondrial inclusions and mitochondrial respiratory function in selenite-treated mammary epithelial cell lines.
Anticancer research 1988;8(1):65-71.
1988: Daniel Medina; D G Morrison
Current ideas on selenium as a chemopreventive agent.
Pathology and immunopathology research 1988;7(3):187-99.
1988: D G Morrison; R C Berdan; D F Pauly; D S Turner; C J Oborn; Daniel Medina
Selenium distribution in mammary epithelial cells reveals its possible mechanism of inhibition of cell growth.
Anticancer research 1988;8(1):51-63.
1987: M S Schwartz; Daniel Medina
Characterization of the DIM series of BALB/c preneoplasms for mouse mammary tumor virus-mediated oncogenesis.
Cancer research 1987;47(21):5707-14.
1987: Daniel Medina; M L Li; C J Oborn; M J Bissell
Casein gene expression in mouse mammary epithelial cell lines: dependence upon extracellular matrix and cell type.
Experimental cell research 1987;172(1):192-203.
1986: Daniel Medina; C J Oborn; Frances S Kittrell; R L Ullrich
Properties of mouse mammary epithelial cell lines characterized by in vivo transplantation and in vitro immunocytochemical methods.
Journal of the National Cancer Institute 1986;76(6):1143-56.
1984: K G Danielson; C J Oborn; E M Durban; Janet S Butel; Daniel Medina
Epithelial mouse mammary cell line exhibiting normal morphogenesis in vivo and functional differentiation in vitro.
Proceedings of the National Academy of Sciences of the United States of America 1984;81(12):3756-60.