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Jean-Louis Mege

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Suzana Pinto Salcedo; Vilma Arce Gorvel; Thais Lourdes Santos Lacerda; Jean-Louis Mege; Amira Ben Amara; José Maria Blasco; Nicolas Chevrier; Chantal de Chastellier; Sarah Gerart; Jean-Pierre Gorvel
Pathogenic brucellae replicate in human trophoblasts.
Wiwit Tantibhedhyangkul; Julien Textoris; Amira Ben Amara; Christian Capo; Eric Ghigo; Laurent Gorvel; Jean-Louis Mege
Orientia tsutsugamushi, the causative agent of scrub typhus, induces an inflammatory program in human macrophages.
Fanny Balique; Abdoulaye Oury Barry; Philippe Colson; Audrey Ferretti; Eric Ghigo; Hervé Lecoq; Hubert Lepidi; Jean-Louis Mege; Khatoun Al Moussawi; Claude Nappez; Tatsiana Ngounga; Didier Raoult
Tobacco mosaic virus in the lungs of mice following intra-tracheal inoculation.

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2013: Suzana Pinto Salcedo; Vilma Arce Gorvel; Thais Lourdes Santos Lacerda; Jean-Louis Mege; Amira Ben Amara; José Maria Blasco; Nicolas Chevrier; Chantal de Chastellier; Sarah Gerart; Jean-Pierre Gorvel
Pathogenic brucellae replicate in human trophoblasts.
The Journal of infectious diseases 2013;207(7):1075-83.
2013: Wiwit Tantibhedhyangkul; Julien Textoris; Amira Ben Amara; Christian Capo; Eric Ghigo; Laurent Gorvel; Jean-Louis Mege
Orientia tsutsugamushi, the causative agent of scrub typhus, induces an inflammatory program in human macrophages.
Microbial pathogenesis 2013;55():55-63.
2013: Fanny Balique; Abdoulaye Oury Barry; Philippe Colson; Audrey Ferretti; Eric Ghigo; Hervé Lecoq; Hubert Lepidi; Jean-Louis Mege; Khatoun Al Moussawi; Claude Nappez; Tatsiana Ngounga; Didier Raoult
Tobacco mosaic virus in the lungs of mice following intra-tracheal inoculation.
PloS one 2013;8(1):e54993.
2013: Valérie Moal; Julien Textoris; Vikram Mehraj; Amira Ben Amara; Yvon Berland; Philippe Colson; Jean-Louis Mege
Chronic hepatitis E virus infection is specifically associated with an interferon-related transcriptional program.
The Journal of infectious diseases 2013;207(1):125-32.
2012: Abdoulaye Oury Barry; Stefano Bonatti; Nicolas Boucherit; Christian Capo; emmanuel lemichez; Jean-Louis Mege; Giovanna Mottola; Angel Nebreda; Philippe Soubeyran; Rudolf Toman; Virginie Trouplin; Pavol Vadovic; Eric Ghigo
Impaired stimulation of p38α-MAPK/Vps41-HOPS by LPS from pathogenic Coxiella burnetii prevents trafficking to microbicidal phagolysosomes.
Cell host & microbe 2012;12(6):751-63.
2012: Vikram Mehraj; Didier Raoult; Julien Textoris; Christian Capo; Marc Leone; Jean-Louis Mege
Overexpression of the Per2 gene in male patients with acute Q fever.
The Journal of infectious diseases 2012;206(11):1768-70.
2012: Yassina Bechah; Jean-Louis Mege; Didier Raoult
Cross-protection among Rickettsia species and subspecies in a guinea pig model of cutaneous infection.
Comparative immunology, microbiology and infectious diseases 2012;35(6):551-6.
2012: Richard Ouedraogo; Christian Capo; Aurélie Daumas; Eric Ghigo; Jean-Louis Mege; Julien Textoris
Whole-cell MALDI-TOF MS: a new tool to assess the multifaceted activation of macrophages.
Journal of proteomics 2012;75(18):5523-32.
2012: Amélie Delaby; Leon Espinosa; Eric Ghigo; Laurent Gorvel; Catherine LéPolard; Christian Capo; Didier Raoult; Jean-Louis Mege
Defective monocyte dynamics in Q fever granuloma deficiency.
The Journal of infectious diseases 2012;205(7):1086-94.
2012: Vikram Mehraj; Giovanna Mottola; Jean-Louis Mege; Amira Ben Amara; Stefano Bonatti; Nicolas Boucherit; Christian Capo; Eric Ghigo
The ligands of Numb proteins X1 and X2 are specific markers for chronic Q fever.
FEMS immunology and medical microbiology 2012;64(1):98-100.
2012: Amira Ben Amara; Yassina Bechah; Jean-Louis Mege
Immune response and Coxiella burnetii invasion.
Advances in experimental medicine and biology 2012;984():287-98.
2012: Christian Capo; Jean-Louis Mege
Role of innate and adaptive immunity in the control of Q fever.
Advances in experimental medicine and biology 2012;984():273-86.
2012: Franck Thuny; Amira Ben Amara; Adil El Filali; Christian Capo; Gilbert Habib; Didier Raoult; Julien Textoris; Jean-Louis Mege
The gene expression analysis of blood reveals S100A11 and AQP9 as potential biomarkers of infective endocarditis.
PloS one 2012;7(2):e31490.
2011: Khatoun Al Moussawi; Nada Malou; Jean-Louis Mege; Didier Raoult; Benoît Desnues
An experimental mouse model to establish Tropheryma whipplei as a diarrheal agent.
The Journal of infectious diseases 2011;204(1):44-50.
2011: Wiwit Tantibhedhyangkul; Thanavadee Prachason; Duangdao Waywa; Adil El Filali; Eric Ghigo; Wanna Thongnoppakhun; Didier Raoult; Yupin Suputtamongkol; Christian Capo; Chanin Limwongse; Jean-Louis Mege
Orientia tsutsugamushi stimulates an original gene expression program in monocytes: relationship with gene expression in patients with scrub typhus.
PLoS neglected tropical diseases 2011;5(5):e1028.
2011: Abdoulaye Oury Barry; Jean-Louis Mege; Eric Ghigo
Hijacked phagosomes and leukocyte activation: an intimate relationship.
Journal of leukocyte biology 2011;89(3):373-82.
2011: Franck Thuny; Gilbert Habib; Yvan Le Dolley; Matthias Canault; Jean-Paul Casalta; Monique Verdier; Jean-François Avierinos; Didier Raoult; Jean-Louis Mege; Pierre Morange; Marie-Christine Alessi
Circulating matrix metalloproteinases in infective endocarditis: a possible marker of the embolic risk.
PloS one 2011;6(4):e18830.
2010: Yassina Bechah; Khalid El Karkouri; Oleg Mediannikov; Quentin Leroy; Nicolas Pelletier; Catherine Robert; Claudine Médigue; Jean-Louis Mege; Didier Raoult
Genomic, proteomic, and transcriptomic analysis of virulent and avirulent Rickettsia prowazekii reveals its adaptive mutation capabilities.
Genome research 2010;20(5):655-63.
2010: Djamel Mokart; Marc Leone; Antoine Sannini; J P Brun; Olivier Turrini; Bernard Lelong; Gilles Houvenaeghel; Jean-Louis Blache; Jean-Louis Mege; Claude Martin
Reduced interleukin-12 release from stimulated monocytes in patients with sepsis after major cancer surgery.
Acta anaesthesiologica Scandinavica 2010;54(5):643-8.
2010: L Gorvel; K Al Moussawi; Eric Ghigo; Christian Capo; Jean-Louis Mege; Benoît Desnues
Tropheryma whipplei, the Whipple's disease bacillus, induces macrophage apoptosis through the extrinsic pathway.
Cell death & disease 2010;1():e34.
2010: Amira Ben Amara; Eric Ghigo; Yannick Le Priol; Catherine LéPolard; Suzana P Salcedo; emmanuel lemichez; Florence Bretelle; Christian Capo; Jean-Louis Mege
Coxiella burnetii, the agent of Q fever, replicates within trophoblasts and induces a unique transcriptional response.
PloS one 2010;5(12):e15315.
2010: Richard Ouedraogo; Christophe Flaudrops; Amira Ben Amara; Christian Capo; Didier Raoult; Jean-Louis Mege
Global analysis of circulating immune cells by matrix-assisted laser desorption ionization time-of-flight mass spectrometry.
PloS one 2010;5(10):e13691.
2010: Eric Ghigo; Abdoulaye Oury Barry; Lionel Pretat; Khatoun Al Moussawi; Benoît Desnues; Christian Capo; Hardy Kornfeld; Jean-Louis Mege
IL-16 promotes T. whipplei replication by inhibiting phagosome conversion and modulating macrophage activation.
PloS one 2010;5(10):e13561.
2010: Julien Textoris; Leang Heng Ban; Christian Capo; Didier Raoult; Marc Leone; Jean-Louis Mege
Sex-related differences in gene expression following Coxiella burnetii infection in mice: potential role of circadian rhythm.
PloS one 2010;5(8):e12190.
2010: Jean-Louis Mege; Christian Capo
[Is macrophage polarization the Gordian knot of bacterial infections?].
Médecine sciences : M/S 2010;26(1):83-8.
2010: Marie Benoit; Franck Thuny; Yannick Le Priol; Hubert Lepidi; Sonia Bastonero; Jean-Paul Casalta; Frédéric Collart; Christian Capo; Didier Raoult; Jean-Louis Mege
The transcriptional programme of human heart valves reveals the natural history of infective endocarditis.
PloS one 2010;5(1):e8939.
2010: Khatoun Al Moussawi; Eric Ghigo; Ulrich Kalinke; Lena Alexopoulou; Jean-Louis Mege; Benoît Desnues
Type I interferon induction is detrimental during infection with the Whipple's disease bacterium, Tropheryma whipplei.
PLoS pathogens 2010;6(1):e1000722.
2010: Yassina Bechah; Christopher D Paddock; Christian Capo; Jean-Louis Mege; Didier Raoult
Adipose tissue serves as a reservoir for recrudescent Rickettsia prowazekii infection in a mouse model.
PloS one 2010;5(1):e8547.
2009: M Benoit; Yassina Bechah; Christian Capo; P J Murray; Jean-Louis Mege; Benoît Desnues
Role of the cytoplasmic pattern recognition receptor Nod2 in Coxiella burnetii infection.
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 2009;15 Suppl 2():154-5.
2009: Yassina Bechah; Christian Capo; Georges E Grau; Didier Raoult; Jean-Louis Mege
Rickettsia prowazekii infection of endothelial cells increases leukocyte adhesion through alphavbeta3 integrin engagement.
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 2009;15 Suppl 2():249-50.
2009: L Pretat; R Toman; P Vadovic; Christian Capo; Jean-Louis Mege; Eric Ghigo
Intracellular trafficking of the Coxiella burnetii lipopolysaccharide.
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 2009;15 Suppl 2():185-7.
2009: Benoît Desnues; Guenièvre Imbert; Didier Raoult; Jean-Louis Mege; Eric Ghigo
Role of specific antibodies in Coxiella burnetii infection of macrophages.
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 2009;15 Suppl 2():161-2.
2009: Eric Ghigo; Lionel Pretat; Benoît Desnues; Christian Capo; Didier Raoult; Jean-Louis Mege
Intracellular life of Coxiella burnetii in macrophages.
Annals of the New York Academy of Sciences 2009;1166():55-66.
2009: Cyrille J Bonhomme; Patricia Renesto; Benoît Desnues; Eric Ghigo; Hubert Lepidi; Patrick Fourquet; Florence Fenollar; Bernard Henrissat; Jean-Louis Mege; Didier Raoult
Tropheryma whipplei glycosylation in the pathophysiologic profile of Whipple's disease.
The Journal of infectious diseases 2009;199(7):1043-52.
2009: Sonia Bastonero; Yannick Le Priol; Martine Armand; Christophe S Bernard; Martine Reynaud-Gaubert; Daniel Olive; Daniel Parzy; Sophie de Bentzmann; Christian Capo; Jean-Louis Mege
New microbicidal functions of tracheal glands: defective anti-infectious response to Pseudomonas aeruginosa in cystic fibrosis.
PloS one 2009;4(4):e5357.
2008: Marie Benoit; Benoît Desnues; Jean-Louis Mege
Macrophage polarization in bacterial infections.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(6):3733-9.
2008: Yassina Bechah; Christian Capo; Jean-Louis Mege; Didier Raoult
Epidemic typhus.
The Lancet infectious diseases 2008;8(7):417-26.
2008: Eric Ghigo; Jürgen Kartenbeck; Pham Lien; Lucas Pelkmans; Christian Capo; Jean-Louis Mege; Didier Raoult
Ameobal pathogen mimivirus infects macrophages through phagocytosis.
PLoS pathogens 2008;4(6):e1000087.
2008: Chafika Mazouni; Christian Capo; Renaud Ledu; Amélie Honstettre; Aubert Agostini; Marianne Capelle; Jean-Louis Mege; Florence Bretelle
Preeclampsia: impaired inflammatory response mediated by Toll-like receptors.
Journal of reproductive immunology 2008;78(1):80-3.
2008: Marie Benoit; Eric Ghigo; Christian Capo; Didier Raoult; Jean-Louis Mege
The uptake of apoptotic cells drives Coxiella burnetii replication and macrophage polarization: a model for Q fever endocarditis.
PLoS pathogens 2008;4(5):e1000066.
2008: Yassina Bechah; Christian Capo; Jean-Louis Mege; Didier Raoult
Rickettsial diseases: from Rickettsia-arthropod relationships to pathophysiology and animal models.
Future microbiology 2008;3(2):223-36.
2008: Marie Benoit; Bernadette Barbarat; Alain Bernard; Daniel Olive; Jean-Louis Mege
Coxiella burnetii, the agent of Q fever, stimulates an atypical M2 activation program in human macrophages.
European journal of immunology 2008;38(4):1065-70.
2008: Didier Raoult; Michel Drancourt; Saïd Azza; Claude Nappez; Régis Guieu; Jean-Marc ROLAIN; Patrick Fourquet; Bernard Campagna; Bernard La Scola; Jean-Louis Mege; Pascal Mansuelle; Eric Lechevalier; Yvon Berland; Jean-Pierre Gorvel; Patricia Renesto
Nanobacteria are mineralo fetuin complexes.
PLoS pathogens 2008;4(2):e41.
2008: Soraya Meghari; Yassina Bechah; Christian Capo; Hubert Lepidi; Didier Raoult; Peter J Murray; Jean-Louis Mege
Persistent Coxiella burnetii infection in mice overexpressing IL-10: an efficient model for chronic Q fever pathogenesis.
PLoS pathogens 2008;4(2):e23.
2008: Djamel Mokart; Eric Kipnis; Pierre Guerre-Berthelot; Norbert Vey; Christian Capo; Antoine Sannini; Jean-Paul Brun; Jean-Louis Blache; Jean-Louis Mege; Didier Blaise; Benoit Guery
Monocyte deactivation in neutropenic acute respiratory distress syndrome patients treated with granulocyte colony-stimulating factor.
Critical care (London, England) 2008;12(1):R17.
2008: Yassina Bechah; Christian Capo; Didier Raoult; Jean-Louis Mege
Infection of endothelial cells with virulent Rickettsia prowazekii increases the transmigration of leukocytes.
The Journal of infectious diseases 2008;197(1):142-7.
2007: Marc Leone; Yassina Bechah; Soraya Meghari; Hubert Lepidi; Christian Capo; Didier Raoult; Jean-Louis Mege
Coxiella burnetii infection in C57BL/6 mice aged 1 or 14 months.
FEMS immunology and medical microbiology 2007;50(3):396-400.
2007: Yassina Bechah; Christian Capo; Georges E Grau; Didier Raoult; Jean-Louis Mege
A murine model of infection with Rickettsia prowazekii: implications for pathogenesis of epidemic typhus.
Microbes and infection / Institut Pasteur 2007;9(7):898-906.
2007: Marie Benoit; Florence Fenollar; Didier Raoult; Jean-Louis Mege
Increased levels of circulating IL-16 and apoptosis markers are related to the activity of Whipple's disease.
PloS one 2007;2(6):e494.
2007: Soraya Meghari; Carole Berruyer; Hubert Lepidi; François Galland; Philippe Naquet; Jean-Louis Mege
Vanin-1 controls granuloma formation and macrophage polarization in Coxiella burnetii infection.
European journal of immunology 2007;37(1):24-32.
2006: Soraya Meghari; Benoît Desnues; Christian Capo; Georges E Grau; Didier Raoult; Jean-Louis Mege
Coxiella burnetii stimulates production of RANTES and MCP-1 by mononuclear cells: modulation by adhesion to endothelial cells and its implication in Q fever.
European cytokine network 2006;17(4):253-9.
2006: Jean-Louis Mege; Soraya Meghari; Amélie Honstettre; Christian Capo; Didier Raoult
The two faces of interleukin 10 in human infectious diseases.
The Lancet infectious diseases 2006;6(9):557-69.
2006: Séverine Genot; Andreas Stein; Hubert Lepidi; Melanie Ihrig; Didier Raoult; Jean-Louis Mege
Murine model of infection by Tropheryma whipplei.
Infection and immunity 2006;74(8):4915-7.
2006: Soraya Meghari; Christian Capo; Didier Raoult; Jean-Louis Mege
Deficient transendothelial migration of leukocytes in Q fever: the role played by interleukin-10.
The Journal of infectious diseases 2006;194(3):365-9.
2006: Laurent Boyer; Laurent Turchi; Benoit Desnues; Anne Doye; Gilles Ponzio; Jean-Louis Mege; Motozo Yamashita; Ying E Zhang; Jacques Bertoglio; Gilles Flatau; Patrice Boquet; emmanuel lemichez
CNF1-induced ubiquitylation and proteasome destruction of activated RhoA is impaired in Smurf1-/- cells.
Molecular biology of the cell 2006;17(6):2489-97.
2006: Amélie Honstettre; Soraya Meghari; Jacques Nunès; Hubert Lepidi; Didier Raoult; Daniel Olive; Jean-Louis Mege
Role for the CD28 molecule in the control of Coxiella burnetii infection.
Infection and immunity 2006;74(3):1800-8.
2006: Benoît Desnues; Melanie Ihrig; Didier Raoult; Jean-Louis Mege
Whipple's disease: a macrophage disease.
Clinical and vaccine immunology : CVI 2006;13(2):170-8.
2006: Soraya Meghari; Jean-Marc ROLAIN; Georges E Grau; Esther Platt; Lina Barrassi; Jean-Louis Mege; Didier Raoult
Antiangiogenic effect of erythromycin: an in vitro model of Bartonella quintana infection.
The Journal of infectious diseases 2006;193(3):380-6.
2005: Soraya Meghari; Amélie Honstettre; Hubert Lepidi; Bernardt Ryffel; Didier Raoult; Jean-Louis Mege
TLR2 is necessary to inflammatory response in Coxiella burnetii infection.
Annals of the New York Academy of Sciences 2005;1063():161-6.
2005: Benoît Desnues; Hubert Lepidi; Didier Raoult; Jean-Louis Mege
Whipple disease: intestinal infiltrating cells exhibit a transcriptional pattern of M2/alternatively activated macrophages.
The Journal of infectious diseases 2005;192(9):1642-6.
2005: Benoît Desnues; Didier Raoult; Jean-Louis Mege
IL-16 is critical for Tropheryma whipplei replication in Whipple's disease.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(7):4575-82.
2005: Gilbert Greub; Benoît Desnues; Didier Raoult; Jean-Louis Mege
Lack of microbicidal response in human macrophages infected with Parachlamydia acanthamoebae.
Microbes and infection / Institut Pasteur 2005;7(4):714-9.
2005: Didier Raoult; Tj Marrie; Jean-Louis Mege
Natural history and pathophysiology of Q fever.
The Lancet infectious diseases 2005;5(4):219-26.
2005: Gilbert Greub; Jean-Louis Mege; Jean-Pierre Gorvel; Didier Raoult; Stéphane Méresse
Intracellular trafficking of Parachlamydia acanthamoebae.
Cellular microbiology 2005;7(4):581-9.
2005: Philippe Brouqui; Andreas Stein; Hervé Tissot Dupont; Pierre Gallian; Sékéné Badiaga; Jean-Marc ROLAIN; Jean-Louis Mege; Bernard La Scola; Philippe Berbis; Didier Raoult
Ectoparasitism and vector-borne diseases in 930 homeless people from Marseilles.
Medicine 2005;84(1):61-8.
2004: Eric Ghigo; Amélie Honstettre; Christian Capo; Jean-Pierre Gorvel; Didier Raoult; Jean-Louis Mege
Link between impaired maturation of phagosomes and defective Coxiella burnetii killing in patients with chronic Q fever.
The Journal of infectious diseases 2004;190(10):1767-72.
2004: Patrick Munro; Gilles Flatau; Anne Doye; Laurent Boyer; Olivier Oregioni; Jean-Louis Mege; Luce Landraud; emmanuel lemichez
Activation and proteasomal degradation of rho GTPases by cytotoxic necrotizing factor-1 elicit a controlled inflammatory response.
The Journal of biological chemistry 2004;279(34):35849-57.
2004: Amélie Honstettre; Eric Ghigo; Alix Moynault; Christian Capo; Rudolf Toman; Shizuo Akira; Osamu Takeuchi; Hubert Lepidi; Didier Raoult; Jean-Louis Mege
Lipopolysaccharide from Coxiella burnetii is involved in bacterial phagocytosis, filamentous actin reorganization, and inflammatory responses through Toll-like receptor 4.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(6):3695-703.
2004: Marc Leone; Amélie Honstettre; Hubert Lepidi; Christian Capo; Francis Bayard; Didier Raoult; Jean-Louis Mege
Effect of sex on Coxiella burnetii infection: protective role of 17beta-estradiol.
The Journal of infectious diseases 2004;189(2):339-45.
2003: Gilbert Greub; Jean-Louis Mege; Didier Raoult
Parachlamydia acanthamoebae enters and multiplies within human macrophages and induces their apoptosis [corrected].
Infection and immunity 2003;71(10):5979-85.
2003: Djamel Mokart; Benoit Guery; Reda Bouabdallah; Claude Martin; Jean-Louis Blache; Christine Arnoulet; Jean-Louis Mege
Deactivation of alveolar macrophages in septic neutropenic ARDS.
Chest 2003;124(2):644-52.
2003: Eric Ghigo; Guenièvre Imbert; Christian Capo; Didier Raoult; Jean-Louis Mege
Interleukin-4 induces Coxiella burnetii replication in human monocytes but not in macrophages.
Annals of the New York Academy of Sciences 2003;990():450-9.
2003: Hubert Lepidi; Florence Fenollar; Rene Gerolami; Jean-Louis Mege; Marie-France Bonzi; Marc Chappuis; José Sahel; Didier Raoult
Whipple's disease: immunospecific and quantitative immunohistochemical study of intestinal biopsy specimens.
Human pathology 2003;34(6):589-96.
2003: Christian Capo; Alix Moynault; Yves Collette; Daniel Olive; Eric J Brown; Didier Raoult; Jean-Louis Mege
Coxiella burnetii avoids macrophage phagocytosis by interfering with spatial distribution of complement receptor 3.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(8):4217-25.
2003: Amélie Honstettre; Guenièvre Imbert; Eric Ghigo; Frédérique Gouriet; Christian Capo; Didier Raoult; Jean-Louis Mege
Dysregulation of cytokines in acute Q fever: role of interleukin-10 and tumor necrosis factor in chronic evolution of Q fever.
The Journal of infectious diseases 2003;187(6):956-62.
2003: Christian Capo; Nathalie Amirayan-Chevillard; Philippe Brouqui; Didier Raoult; Jean-Louis Mege
Bartonella quintana bacteremia and overproduction of interleukin-10: model of bacterial persistence in homeless people.
The Journal of infectious diseases 2003;187(5):837-44.
2002: Jérôme Dellacasagrande; Eric Ghigo; Didier Raoult; Christian Capo; Jean-Louis Mege
IFN-gamma-induced apoptosis and microbicidal activity in monocytes harboring the intracellular bacterium Coxiella burnetii require membrane TNF and homotypic cell adherence.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(11):6309-15.
2002: Djamel Mokart; Christian Capo; Jean-Louis Blache; Jean-Robert Delpero; Gilles Houvenaeghel; Claude Martin; Jean-Louis Mege
Early postoperative compensatory anti-inflammatory response syndrome is associated with septic complications after major surgical trauma in patients with cancer.
The British journal of surgery 2002;89(11):1450-6.
2002: Eric Ghigo; Christian Capo; Ching-Hsuan Tung; Didier Raoult; Jean-Pierre Gorvel; Jean-Louis Mege
Coxiella burnetii survival in THP-1 monocytes involves the impairment of phagosome maturation: IFN-gamma mediates its restoration and bacterial killing.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(8):4488-95.
2002: Eric Ghigo; Christian Capo; Marianne Aurouze; Ching-Hsuan Tung; Jean-Pierre Gorvel; Didier Raoult; Jean-Louis Mege
Survival of Tropheryma whipplei, the agent of Whipple's disease, requires phagosome acidification.
Infection and immunity 2002;70(3):1501-6.
2001: Sonia Meconi; Christian Capo; Maryse Remacle-Bonnet; gilbert pommier; Didier Raoult; Jean-Louis Mege
Activation of protein tyrosine kinases by Coxiella burnetii: role in actin cytoskeleton reorganization and bacterial phagocytosis.
Infection and immunity 2001;69(4):2520-6.
2001: Eric Ghigo; Christian Capo; Didier Raoult; Jean-Louis Mege
Interleukin-10 stimulates Coxiella burnetii replication in human monocytes through tumor necrosis factor down-modulation: role in microbicidal defect of Q fever.
Infection and immunity 2001;69(4):2345-52.
2000: Jérôme Dellacasagrande; Eric Ghigo; S M Hammami; R Toman; Didier Raoult; Christian Capo; Jean-Louis Mege
alpha(v)beta(3) integrin and bacterial lipopolysaccharide are involved in Coxiella burnetii-stimulated production of tumor necrosis factor by human monocytes.
Infection and immunity 2000;68(10):5673-8.
2000: Nathalie Amirayan-Chevillard; Hervé Tissot-Dupont; Yolande Obadia; Hervé Gallais; Jean-Louis Mege; Christian Capo
Highly active antiretroviral therapy (HAART) and circulating markers of immune activation: specific effect of HAART on neopterin.
Clinical and diagnostic laboratory immunology 2000;7(5):832-4.
2000: Eric Ghigo; Christian Capo; N Amirayan; Didier Raoult; Jean-Louis Mege
The 75-kD tumour necrosis factor (TNF) receptor is specifically up-regulated in monocytes during Q fever endocarditis.
Clinical and experimental immunology 2000;121(2):295-301.
2000: Jérôme Dellacasagrande; P A Moulin; C Guilianelli; Christian Capo; Didier Raoult; Georges E Grau; Jean-Louis Mege
Reduced transendothelial migration of monocytes infected by Coxiella burnetii.
Infection and immunity 2000;68(6):3784-6.
2000: Nathalie Amirayan-Chevillard; Hervé Tissot-Dupont; Christian Capo; C Brunet; F Dignat-George; Y Obadia; Hervé Gallais; Jean-Louis Mege
Impact of highly active anti-retroviral therapy (HAART) on cytokine production and monocyte subsets in HIV-infected patients.
Clinical and experimental immunology 2000;120(1):107-12.
2000: G Tardei; Dan Duiculescu; Christian Capo; Carmen C Diaconu; A Mutiu; Jean-Louis Mege; Costin Cernescu
Phagocytic function of monocytes in children with human immunodeficiency virus type 1 infection.
Clinical and diagnostic laboratory immunology 2000;7(2):296-7.
2000: Andreas Stein; Hubert Lepidi; Jean-Louis Mege; T J Marrie; Didier Raoult
Repeated pregnancies in BALB/c mice infected with Coxiella burnetii cause disseminated infection, resulting in stillbirth and endocarditis.
The Journal of infectious diseases 2000;181(1):188-94.
2000: Jérôme Dellacasagrande; Eric Ghigo; Christian Capo; Didier Raoult; Jean-Louis Mege
Coxiella burnetii survives in monocytes from patients with Q fever endocarditis: involvement of tumor necrosis factor.
Infection and immunity 2000;68(1):160-4.
1999: Christian Capo; F P Lindberg; Sonia Meconi; Y Zaffran; G Tardei; E J Brown; Didier Raoult; Jean-Louis Mege
Subversion of monocyte functions by coxiella burnetii: impairment of the cross-talk between alphavbeta3 integrin and CR3.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(11):6078-85.
1999: Jérôme Dellacasagrande; Christian Capo; Didier Raoult; Jean-Louis Mege
IFN-gamma-mediated control of Coxiella burnetii survival in monocytes: the role of cell apoptosis and TNF.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(4):2259-65.
1999: Christian Capo; N Amirayan; Eric Ghigo; Didier Raoult; Jean-Louis Mege
Circulating cytokine balance and activation markers of leucocytes in Q fever.
Clinical and experimental immunology 1999;115(1):120-3.
1998: Christian Capo; I Iorgulescu; M Mutillod; Jean-Louis Mege; Didier Raoult
Increases in the levels of Coxiella burnetii-specific immunoglobulin G1 and G3 antibodies in acute Q fever and chronic Q fever.
Clinical and diagnostic laboratory immunology 1998;5(6):814-6.
1998: Sonia Meconi; V Jacomo; Patrice Boquet; Didier Raoult; Jean-Louis Mege; Christian Capo
Coxiella burnetii induces reorganization of the actin cytoskeleton in human monocytes.
Infection and immunity 1998;66(11):5527-33.
1998: Christian Capo; Sonia Meconi; M V Sanguedolce; Nathalie Bardin; Gilles Flatau; Patrice Boquet; Jean-Louis Mege
Effect of cytotoxic necrotizing factor-1 on actin cytoskeleton in human monocytes: role in the regulation of integrin-dependent phagocytosis.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(8):4301-8.
1998: Philippe Brunet; Christian Capo; Jérôme Dellacasagrande; Xavier Thirion; Jean-Louis Mege; Yvon Berland
IL-10 synthesis and secretion by peripheral blood mononuclear cells in haemodialysis patients.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 1998;13(7):1745-51.
1997: Jean-Louis Mege; Max MAURIN; Christian Capo; Didier Raoult
Coxiella burnetii: the 'query' fever bacterium. A model of immune subversion by a strictly intracellular microorganism.
FEMS microbiology reviews 1997;19(4):209-17.
1996: Christian Capo; Y Zaffran; F Zugun; P Houpikian; Didier Raoult; Jean-Louis Mege
Production of interleukin-10 and transforming growth factor beta by peripheral blood mononuclear cells in Q fever endocarditis.
Infection and immunity 1996;64(10):4143-7.
1996: Jean-Louis Mege; Christian Capo; R Purgus; M Olmer
Monocyte production of transforming growth factor beta in long-term hemodialysis: modulation by hemodialysis membranes.
American journal of kidney diseases : the official journal of the National Kidney Foundation 1996;28(3):395-9.
1996: Christian Capo; F Zugun; A Stein; G Tardei; H Lepidi; Didier Raoult; Jean-Louis Mege
Upregulation of tumor necrosis factor alpha and interleukin-1 beta in Q fever endocarditis.
Infection and immunity 1996;64(5):1638-42.
1996: Antoine Magnan; Jean-Louis Mege; J C Escallier; J Brisse; Christian Capo; M Reynaud; pascal Thomas; B Meric; Louise Garbe; Monique Badier; L Viard; Pierre Bongrand; Roger Giudicelli; Dominique Metras; Pierre Fuentes; Daniel Vervloet; M Noirclerc
Balance between alveolar macrophage IL-6 and TGF-beta in lung-transplant recipients. Marseille and Montréal Lung Transplantation Group.
American journal of respiratory and critical care medicine 1996;153(4 Pt 1):1431-6.
1995: Y Zaffran; J C Escallier; Simona Ruta; Christian Capo; Jean-Louis Mege
Zymosan-triggered association of tyrosine phosphoproteins and lyn kinase with cytoskeleton in human monocytes.
Journal of immunology (Baltimore, Md. : 1950) 1995;154(7):3488-97.
1995: H Lepidi; Y Zaffran; J L Ansaldi; Jean-Louis Mege; Christian Capo
Morphological polarization of human polymorphonuclear leucocytes in response to three different chemoattractants: an effector response independent of calcium rise and tyrosine kinases.
Journal of cell science 1995;108 ( Pt 4)():1771-8.
1994: Antoine Magnan; Jean-Louis Mege; M Reynaud; pascal Thomas; Christian Capo; Louise Garbe; B Meric; Monique Badier; Pierre Bongrand; L Viard
Monitoring of alveolar macrophage production of tumor necrosis factor-alpha and interleukin-6 in lung transplant recipients. Marseille and Montreal Lung Transplantation Group.
American journal of respiratory and critical care medicine 1994;150(3):684-9.
1994: Jean Marc Durand; Jean-Louis Mege; J C Escallier; Gilles Kaplanski; Jacques Soubeyrand
Antineutrophil cytoplasmic antibodies and endocarditis.
Clinical and experimental rheumatology 1994;12(5):579.
1994: H Lepidi; R Ciubotariu; Pierre Bongrand; Christian Capo; R Barot-Ciorbaru; Jean-Louis Mege
Protein tyrosine kinases and TNF alpha secretion in human monocytes.
International journal of immunopharmacology 1994;16(5-6):407-12.
1994: T Jacob; J C Escallier; M V Sanguedolce; C Chicheportiche; Pierre Bongrand; Christian Capo; Jean-Louis Mege
Legionella pneumophila inhibits superoxide generation in human monocytes via the down-modulation of alpha and beta protein kinase C isotypes.
Journal of leukocyte biology 1994;55(3):310-2.
1993: Jean-Louis Mege; N Dilsen; V Sanguedolce; A Gul; P Bongrand; H Roux; Lale Ocal; M Inanç; Christian Capo
Overproduction of monocyte derived tumor necrosis factor alpha, interleukin (IL) 6, IL-8 and increased neutrophil superoxide generation in Behçet's disease. A comparative study with familial Mediterranean fever and healthy subjects.
The Journal of rheumatology 1993;20(9):1544-9.
1993: Y Zaffran; H Lepidi; Pierre Bongrand; Jean-Louis Mege; Christian Capo
F-actin content and spatial distribution in resting and chemoattractant-stimulated human polymorphonuclear leucocytes. Which role for intracellular free calcium?
Journal of cell science 1993;105 ( Pt 3)():675-84.
1993: Jean-Louis Mege; M V Sanguedolce; T Jacob; Pierre Bongrand; Christian Capo; E B Myssiakine; R Barot-Ciorbaru
Nocardia fractions, NLD and NWSM, induce tumor necrosis factor-alpha secretion in human monocytes: role of protein kinase C.
European journal of immunology 1993;23(7):1582-7.
1993: M V Sanguedolce; Christian Capo; Mohamad Bouhamdan; Pierre Bongrand; C K Huang; Jean-Louis Mege
Zymosan-induced tyrosine phosphorylations in human monocytes. Role of protein kinase C.
Journal of immunology (Baltimore, Md. : 1950) 1993;151(1):405-14.
1993: Jean-Louis Mege; J C Escallier; Christian Capo; Pierre Bongrand; J G Velut; N Quiles; Jacques Soubeyrand; Jean Marc Durand
Anti-neutrophil cytoplasmic antibodies (ANCA) and infection.
Advances in experimental medicine and biology 1993;336():353-6.
1993: Jean Marc Durand; Jean-Louis Mege; J G Velut; J C Escallier; Gilles Kaplanski; N Quiles; Pierre Bongrand; Jacques Soubeyrand
Antineutrophil cytoplasmic antibodies and infection.
Autoimmunity 1993;15(1):81-3.
1992: N Dilşen; Ahmet Gül; Jean-Louis Mege; M V Sanguedolce
Tumor necrosis factor in pathogenesis of familial Mediterranean fever.
The American journal of medicine 1992;93(5):587.
1992: Jean-Louis Mege; M V Sanguedolce; R Purgus; Bruno Moulin; Pierre Bongrand; Christian Capo; M Olmer
Chronic and intradialytic effects of high-flux hemodialysis on tumor necrosis factor-alpha production: relationship to endotoxins.
American journal of kidney diseases : the official journal of the National Kidney Foundation 1992;20(5):482-8.
1992: H Lepidi; Anne-Marie Benoliel; Jean-Louis Mege; Pierre Bongrand; Christian Capo
Double localization of F-actin in chemoattractant-stimulated polymorphonuclear leucocytes.
Journal of cell science 1992;103 ( Pt 1)():145-56.
1992: M V Sanguedolce; Christian Capo; Pierre Bongrand; Jean-Louis Mege
Zymosan-stimulated tumor necrosis factor-alpha production by human monocytes. Down-modulation by phorbol ester.
Journal of immunology (Baltimore, Md. : 1950) 1992;148(7):2229-36.
1991: Jean-Louis Mege; M Olmer; R Purgus; P Bertocchio; Catherine Farnarier; S Kaplanski; Christian Capo; Pierre Bongrand
Haemodialysis membranes modulate chronically the production of TNF alpha, IL1 beta and IL6.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 1991;6(11):868-75.
1988: P Berbis; Jean-Louis Mege; Christian Capo; S Kaplanski; Pierre Bongrand; Y Privat
Hyperimmunoglobulin E and impaired neutrophil functions in a case of pyoderma gangrenosum: effect of clofazimine.
Journal of the American Academy of Dermatology 1988;18(3):574-6.
1988: Jean-Louis Mege; Christian Capo; B Michel; J L Gastaut; Pierre Bongrand
Phagocytic cell function in aged subjects.
Neurobiology of aging 1988;9(2):217-20.