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Aram Megighian

Research Profile

Anatomy

Chemicals & Drugs

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Muscle Contraction

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TOP 3
Ornella Rossetto; M Scorzeto; Aram Megighian; Cesare Montecucco
Botulinum neurotoxins.
Ornella Rossetto; M Scorzeto; Aram Megighian; Cesare Montecucco
Tetanus neurotoxin.
Elena Bortoloso; Sandra Furlan; Luisa Gorza; Aram Megighian; Pompeo Volpe
Homer 2 antagonizes protein degradation in slow-twitch skeletal muscles.

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All Publications

2013: Ornella Rossetto; M Scorzeto; Aram Megighian; Cesare Montecucco
Botulinum neurotoxins.
Toxicon : official journal of the International Society on Toxinology 2013;67():31-6.
2013: Ornella Rossetto; M Scorzeto; Aram Megighian; Cesare Montecucco
Tetanus neurotoxin.
Toxicon : official journal of the International Society on Toxinology 2013;66():59-63.
2013: Elena Bortoloso; Sandra Furlan; Luisa Gorza; Aram Megighian; Pompeo Volpe
Homer 2 antagonizes protein degradation in slow-twitch skeletal muscles.
American journal of physiology. Cell physiology 2013;304(1):C68-77.
2011: Maria Giovanna Rossetto; Michele Scorzeto; Erica Zanarella; Antonio V Delgado-Escueta; Vimlesh Kumar; Aram Megighian; Genny Orso; Andrea Daga
Defhc1.1, a homologue of the juvenile myoclonic gene EFHC1, modulates architecture and basal activity of the neuromuscular junction in Drosophila.
Human molecular genetics 2011;20(21):4248-57.
2010: Aram Megighian; Michele Scorzeto; Damiano Zanini; Sergio Pantano; Michela Rigoni; Clara Benna; Ornella Rossetto; Cesare Montecucco; Mauro Zordan
Arg206 of SNAP-25 is essential for neuroexocytosis at the Drosophila melanogaster neuromuscular junction.
Journal of cell science 2010;123(Pt 19):3276-83.
2010: Angus G McQuibban; Nicholas Joza; Aram Megighian; Michele Scorzeto; Damiano Zanini; Siegfried Reipert; Constance Richter; Rudolf J Schweyen; Karin Nowikovsky
A Drosophila mutant of LETM1, a candidate gene for seizures in Wolf-Hirschhorn syndrome.
Human molecular genetics 2010;19(6):987-1000.
2010: marta canato; M Dal Maschio; F Sbrana; R Raiteri; Carlo Reggiani; S Vassanelli; Aram Megighian
Mechanical and electrophysiological properties of the sarcolemma of muscle fibers in two murine models of muscle dystrophy: col6a1-/- and mdx.
Journal of biomedicine & biotechnology 2010;2010():981945.
2009: Samantha Peron; Mauro A Zordan; Anna Magnabosco; Carlo Reggiani; Aram Megighian
From action potential to contraction: neural control and excitation-contraction coupling in larval muscles of Drosophila.
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 2009;154(2):173-83.
2009: Clara Benna; Samantha Peron; Giorgia Rizzo; Georgine Faulkner; Aram Megighian; Giuliana Perini; Giuseppe Tognon; Giorgio Valle; Carlo Reggiani; Rodolfo Costa; Mauro A Zordan
Post-transcriptional silencing of the Drosophila homolog of human ZASP: a molecular and functional analysis.
Cell and tissue research 2009;337(3):463-76.
2007: Jennifer A Suggs; Anthony Cammarato; William A Kronert; Massoud Nikkhoy; Corey M Dambacher; Aram Megighian; Sanford I Bernstein
Alternative S2 hinge regions of the myosin rod differentially affect muscle function, myofibril dimensions and myosin tail length.
Journal of molecular biology 2007;367(5):1312-29.
2007: Aram Megighian; Michela Rigoni; Paola Caccin; Mauro A Zordan; Cesare Montecucco
A lysolecithin/fatty acid mixture promotes and then blocks neurotransmitter release at the Drosophila melanogaster larval neuromuscular junction.
Neuroscience letters 2007;416(1):6-11.
2006: Anna Raffaello; Paolo Laveder; Chiara Romualdi; Camilla Bean; Luana Toniolo; Elena Germinario; Aram Megighian; Daniela Danieli-Betto; Carlo Reggiani; Gerolamo Lanfranchi
Denervation in murine fast-twitch muscle: short-term physiological changes and temporal expression profiling.
Physiological genomics 2006;25(1):60-74.
2006: Elena Bortoloso; Nadia Pilati; Aram Megighian; Elisa Tibaldo; Dorianna Sandonà; Pompeo Volpe
Transition of Homer isoforms during skeletal muscle regeneration.
American journal of physiology. Cell physiology 2006;290(3):C711-8.
2006: Mauro A Zordan; Paola Cisotto; Clara Benna; Alessandro Agostino; Giorgia Rizzo; Alberto Piccin; Mirko Pegoraro; Federica Sandrelli; Giuliana Perini; Giuseppe Tognon; Raffaele De Caro; Samantha Peron; Truus Te Kronniè; Aram Megighian; Carlo Reggiani; Massimo Zeviani; Rodolfo Costa
Post-transcriptional silencing and functional characterization of the Drosophila melanogaster homolog of human Surf1.
Genetics 2006;172(1):229-41.
2005: Mauro A Zordan; Michele Massironi; Maria Giovanna Ducato; Geertruy Te Kronnie; Rodolfo Costa; Carlo Reggiani; Carine Chagneau; Jean-René Martin; Aram Megighian
Drosophila CAKI/CMG protein, a homolog of human CASK, is essential for regulation of neurotransmitter vesicle release.
Journal of neurophysiology 2005;94(2):1074-83.
2005: Daniela Danieli-Betto; Elena Germinario; Alessandra Esposito; Aram Megighian; Menotti Midrio; Barbara Ravara; Ernesto Damiani; Luciano Dalla Libera; Roger A Sabbadini; Romeo Betto
Sphingosine 1-phosphate protects mouse extensor digitorum longus skeletal muscle during fatigue.
American journal of physiology. Cell physiology 2005;288(6):C1367-73.
2005: Ana Beramendi; Samantha Peron; Aram Megighian; Carlo Reggiani; Rafael Cantera
The inhibitor kappaB-ortholog Cactus is necessary for normal neuromuscular function in Drosophila melanogaster.
Neuroscience 2005;134(2):397-406.
2004: Elena Germinario; Alessandra Esposito; Aram Megighian; Menotti Midrio; Romeo Betto; Daniela Danieli-Betto
Effects of modulators of sarcoplasmic Ca2+ release on the development of skeletal muscle fatigue.
Journal of applied physiology (Bethesda, Md. : 1985) 2004;96(2):645-9.
2003: William Irwin; Natascha Bergamin; Patrizia Sabatelli; Carlo Reggiani; Aram Megighian; Luciano Merlini; Paola Braghetta; Marta Columbaro; Dino Volpin; Giorgio M Bressan; Paolo Bernardi; Paolo Bonaldo
Mitochondrial dysfunction and apoptosis in myopathic mice with collagen VI deficiency.
Nature genetics 2003;35(4):367-71.
2003: Carmen Bolatto; Silvia Chifflet; Aram Megighian; Rafael Cantera
Synaptic activity modifies the levels of Dorsal and Cactus at the neuromuscular junction of Drosophila.
Journal of neurobiology 2003;54(3):525-36.
2002: Elena Germinario; Alessandra Esposito; Aram Megighian; Menotti Midrio; Donatella Biral; Romeo Betto; Daniela Danieli-Betto
Early changes of type 2B fibers after denervation of rat EDL skeletal muscle.
Journal of applied physiology (Bethesda, Md. : 1985) 2002;92(5):2045-52.
2002: Giuseppe D'Antona; Aram Megighian; Susan Bortolotto; Maria Antonietta Pellegrino; Rosario Marchese-Ragona; Alberto Staffieri; Roberto Bottinelli; Carlo Reggiani
Contractile properties and myosin heavy chain isoform composition in single fibre of human laryngeal muscles.
Journal of muscle research and cell motility 2002;23(3):187-95.
2001: Federica Sandrelli; S Campesan; Monica Rossetto; Clara Benna; E Zieger; Aram Megighian; M Couchman; Charalambos P Kyriacou; Rodolfo Costa
Molecular Dissection of the 5' Region of no-on-transientA of Drosophila melanogaster Reveals cis-Regulation by Adjacent dGpi1 Sequences.
Genetics 2001;157(2):765-75.
2001: S Campesan; D Chalmers; Federica Sandrelli; Aram Megighian; Alexandre A Peixoto; Rodolfo Costa; Charalambos P Kyriacou
Comparative analysis of the nonA region in Drosophila identifies a highly diverged 5' gene that may constrain nonA promoter evolution.
Genetics 2001;157(2):751-64.
2001: Aram Megighian; Mauro A Zordan; Rodolfo Costa
Giant neuron pathway neurophysiological activity in per(0) mutants of Drosophila melanogaster.
Journal of neurogenetics 2001;15(3-4):221-31.
2001: Aram Megighian; Elena Germinario; Katia Rossini; Menotti Midrio; Daniela Danieli-Betto
Nerve control of type 2A MHC isoform expression in regenerating slow skeletal muscle.
Muscle & nerve 2001;24(1):47-53.
1998: Menotti Midrio; Daniela Danieli-Betto; Alessandra Esposito; Aram Megighian; Ugo Carraro; C Catani; Katia Rossini
Lack of type 1 and type 2A myosin heavy chain isoforms in rat slow muscle regenerating during chronic nerve block.
Muscle & nerve 1998;21(2):226-32.
1997: Menotti Midrio; Daniela Danieli-Betto; Aram Megighian; Romeo Betto
Early effects of denervation on sarcoplasmic reticulum properties of slow-twitch rat muscle fibres.
Pflügers Archiv : European journal of physiology 1997;434(4):398-405.
1995: Daniela Danieli-Betto; Romeo Betto; Aram Megighian; Menotti Midrio; Giovanni Salviati; L Larsson
Effects of age on sarcoplasmic reticulum properties and histochemical composition of fast- and slow-twitch rat muscles.
Acta physiologica Scandinavica 1995;154(1):59-64.
1992: Menotti Midrio; Daniela Danieli-Betto; Aram Megighian; C Velussi; C Catani; Ugo Carraro
Slow-to-fast transformation of denervated soleus muscle of the rat, in the presence of an antifibrillatory drug.
Pflügers Archiv : European journal of physiology 1992;420(5-6):446-50.