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Christopher Mehlin

Research Profile

Procedures

Chemicals & Drugs

Genes & Molecular Sequences

Amino Acid Sequences

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Publications

TOP 3
Min Shen; Sophia Siu; Samantha Byrd; Kurt H Edelmann; Neha Patel; Randal R Ketchem; Christopher Mehlin; Heather A Arnett; Haruki Hasegawa
Diverse functions of reactive cysteines facilitate unique biosynthetic processes of aggregate-prone interleukin-31.
Ai Ching Lim; Randal R Ketchem; Luis Borges; Teresa Carabeo; Jane Carter; Joseph E Hoover; Zhonghua Hu; Michael Wittekind; Hongxing Zhou; Christopher Mehlin
A diversity of antibody epitopes can induce signaling through the erythropoietin receptor.
Jane Carter; Jue Zhang; Thien-Lan Dang; Haruki Hasegawa; Janet D Cheng; Irene Gianan; Jason W O'Neill; Martin Wolfson; Sophia Siu; Sheldon Qu; David Meininger; Helen Kim; John Delaney; Christopher Mehlin
Fusion partners can increase the expression of recombinant interleukins via transient transfection in 2936E cells.

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All Publications

2011: Min Shen; Sophia Siu; Samantha Byrd; Kurt H Edelmann; Neha Patel; Randal R Ketchem; Christopher Mehlin; Heather A Arnett; Haruki Hasegawa
Diverse functions of reactive cysteines facilitate unique biosynthetic processes of aggregate-prone interleukin-31.
Experimental cell research 2011;317(7):976-93.
2010: Ai Ching Lim; Randal R Ketchem; Luis Borges; Teresa Carabeo; Jane Carter; Joseph E Hoover; Zhonghua Hu; Michael Wittekind; Hongxing Zhou; Christopher Mehlin
A diversity of antibody epitopes can induce signaling through the erythropoietin receptor.
Biochemistry 2010;49(18):3797-804.
2010: Jane Carter; Jue Zhang; Thien-Lan Dang; Haruki Hasegawa; Janet D Cheng; Irene Gianan; Jason W O'Neill; Martin Wolfson; Sophia Siu; Sheldon Qu; David Meininger; Helen Kim; John Delaney; Christopher Mehlin
Fusion partners can increase the expression of recombinant interleukins via transient transfection in 2936E cells.
Protein science : a publication of the Protein Society 2010;19(2):357-62.
2006: Jürgen Bosch; Mark A Robien; Christopher Mehlin; Erica Boni; Aaron Riechers; Frederick S Buckner; Wesley C Van Voorhis; Peter J Myler; Elizabeth A Worthey; George deTitta; Joseph Luft; Angela Lauricella; Stacey Gulde; Lori A Anderson; Oleksandr Kalyuzhniy; Helen M Neely; Jenni Ross; Thomas N Earnest; Michael Soltis; Lori Schoenfeld; Frank Zucker; Ethan A Merritt; Erkang Fan; Christophe Verlinde; Wim G J Hol
Using fragment cocktail crystallography to assist inhibitor design of Trypanosoma brucei nucleoside 2-deoxyribosyltransferase.
Journal of medicinal chemistry 2006;49(20):5939-46.
2006: Christopher Mehlin; Erica Boni; Frederick S Buckner; Linnea Engel; Tiffany Feist; Michael H Gelb; Lutfiyah Haji; David Kim; Colleen Liu; Natascha Mueller; Peter J Myler; J T Reddy; Joshua N Sampson; E Subramanian; Wesley C Van Voorhis; Elizabeth A Worthey; Frank Zucker; Wim G J Hol
Heterologous expression of proteins from Plasmodium falciparum: results from 1000 genes.
Molecular and biochemical parasitology 2006;148(2):144-60.
2006: Margaret A Holmes; Frederick S Buckner; Wesley C Van Voorhis; Christophe Verlinde; Christopher Mehlin; Erica Boni; George deTitta; Joseph Luft; Angela Lauricella; Lori Anderson; Oleksandr Kalyuzhniy; Frank Zucker; Lori W Schoenfeld; Thomas N Earnest; Wim G J Hol; Ethan A Merritt
Structure of ribose 5-phosphate isomerase from Plasmodium falciparum.
Acta crystallographica. Section F, Structural biology and crystallization communications 2006;62(Pt 5):427-31.
2006: Mark A Robien; Jürgen Bosch; Frederick S Buckner; Wesley C Van Voorhis; Elizabeth A Worthey; Peter J Myler; Christopher Mehlin; Erica Boni; Oleksandr Kalyuzhniy; Lori Anderson; Angela Lauricella; Stacey Gulde; Joseph Luft; George deTitta; Jonathan M Caruthers; Keith O Hodgson; Michael Soltis; Frank Zucker; Christophe Verlinde; Ethan A Merritt; Lori W Schoenfeld; Wim G J Hol
Crystal structure of glyceraldehyde-3-phosphate dehydrogenase from Plasmodium falciparum at 2.25 A resolution reveals intriguing extra electron density in the active site.
Proteins 2006;62(3):570-7.
2006: Margaret A Holmes; Frederick S Buckner; Wesley C Van Voorhis; Christopher Mehlin; Erica Boni; Thomas N Earnest; George deTitta; Joseph Luft; Angela Lauricella; Lori Anderson; Oleksandr Kalyuzhniy; Frank Zucker; Lori W Schoenfeld; Wim G J Hol; Ethan A Merritt
Structure of the conserved hypothetical protein MAL13P1.257 from Plasmodium falciparum.
Acta crystallographica. Section F, Structural biology and crystallization communications 2006;62(Pt 3):180-5.
2006: Jonathan M Caruthers; Jürgen Bosch; Frederick S Buckner; Wesley C Van Voorhis; Peter J Myler; Elizabeth A Worthey; Christopher Mehlin; Erica Boni; George deTitta; Joseph Luft; Angela Lauricella; Oleksandr Kalyuzhniy; Lori Anderson; Frank Zucker; Michael Soltis; Wim G J Hol
Structure of a ribulose 5-phosphate 3-epimerase from Plasmodium falciparum.
Proteins 2006;62(2):338-42.
2005: Jonathan M Caruthers; Frank Zucker; Elizabeth A Worthey; Peter J Myler; Frederick S Buckner; Wes Van Voorhuis; Christopher Mehlin; Erica Boni; Tiffany Feist; Joseph Luft; Stacey Gulde; Angela Lauricella; Oleksandr Kaluzhniy; Lori Anderson; Isolde Le Trong; Margaret A Holmes; Thomas N Earnest; Michael Soltis; Keith O Hodgson; Wim G J Hol; Ethan A Merritt
Crystal structures and proposed structural/functional classification of three protozoan proteins from the isochorismatase superfamily.
Protein science : a publication of the Protein Society 2005;14(11):2887-94.
2005: Claudia Schnick; Mark A Robien; Andrzej M Brzozowski; Eleanor J Dodson; Garib N Murshudov; Lori Anderson; Joseph Luft; Christopher Mehlin; Wim G J Hol; James A Brannigan; Anthony J Wilkinson
Structures of Plasmodium falciparum purine nucleoside phosphorylase complexed with sulfate and its natural substrate inosine.
Acta crystallographica. Section D, Biological crystallography 2005;61(Pt 9):1245-54.
2005: Christopher Mehlin
Structure-based drug discovery for Plasmodium falciparum.
Combinatorial chemistry & high throughput screening 2005;8(1):5-14.
2004: Christopher Mehlin
Measurement of VLA-4/CS-1 and VLA-4/VCAM adhesion inhibition.
Current protocols in pharmacology / editorial board, S.J. Enna (editor-in-chief) ... [et al.] 2004;Chapter 12():Unit 12.7.
2004: Christopher Mehlin; Erica Boni; Jamie Andreyka; Richard W Terry
Cloning grills: high throughput cloning for structural genomics.
Journal of structural and functional genomics 2004;5(1-2):59-61.
2004: Junpeng Deng; Douglas R Davies; Goragot Wisedchaisri; Meiting Wu; Wim G J Hol; Christopher Mehlin
An improved protocol for rapid freezing of protein samples for long-term storage.
Acta crystallographica. Section D, Biological crystallography 2004;60(Pt 1):203-4.
2003: marcin stasiak; Christopher Mehlin; Erica Boni; Tomas Vaisar; Thomas Little; Hwa-Ok Kim; Maher Qabar
Sulphonamide-based small molecule VLA-4 antagonists.
Bioorganic & medicinal chemistry letters 2003;13(21):3875-8.
2003: Christopher Mehlin; Carole Crittenden; Jamie Andreyka
No-wash dyes for calcium flux measurement.
BioTechniques 2003;34(1):164-6.
1999: Christopher Mehlin; CM Headley; Seymour J Klebanoff
An inflammatory polypeptide complex from Staphylococcus epidermidis: isolation and characterization.
The Journal of experimental medicine 1999;189(6):907-18.
1999: Seymour J Klebanoff; D Heather Watts; Christopher Mehlin; CM Headley
Lactobacilli and vaginal host defense: activation of the human immunodeficiency virus type 1 long terminal repeat, cytokine production, and NF-kappaB.
The Journal of infectious diseases 1999;179(3):653-60.
1997: Seymour J Klebanoff; Christopher Mehlin; CM Headley
Activation of the HIV type 1 long terminal repeat and viral replication by dimethylsulfoxide and related solvents.
AIDS research and human retroviruses 1997;13(14):1221-7.
1997: Peter Kiener; PM Davis; Gary C Starling; Christopher Mehlin; Seymour J Klebanoff; Jeffrey A Ledbetter; W Conrad Liles
Differential induction of apoptosis by Fas-Fas ligand interactions in human monocytes and macrophages.
The Journal of experimental medicine 1997;185(8):1511-6.