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Majid Mehtali

Research Profile

Chemicals & Drugs

Procedures

Genetic Therapy

Living Beings

Devices

Gene Transfer Techniques

Anatomy

Genes & Molecular Sequences

Transgenes

Physiology

Disorders

Acquired Immunodeficiency Syndrome

Co-author Network

Publications

TOP 3
Stephen W Brown; Majid Mehtali
The Avian EB66(R) Cell Line, Application to Vaccines, and Therapeutic Protein Production.
Stéphane Olivier; Majid Mehtali
[Alternative production systems for therapeutic monoclonal antibodies].
H Haegel-Kronenberger; Krista G Haanstra; C Ziller-Remy; Antonio Ortiz Buijsse; Jan Vermeiren; F Stoeckel; Stefaan W Van Gool; Jan L Ceuppens; Majid Mehtali; Mark de Boer; margreet jonker; Louis Boon
Inhibition of costimulation allows for repeated systemic administration of adenoviral vector in rhesus monkeys.

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All Publications

2010: Stephen W Brown; Majid Mehtali
The Avian EB66(R) Cell Line, Application to Vaccines, and Therapeutic Protein Production.
PDA journal of pharmaceutical science and technology / PDA 2010;64(5):419-25.
2009: Stéphane Olivier; Majid Mehtali
[Alternative production systems for therapeutic monoclonal antibodies].
Médecine sciences : M/S 2009;25(12):1163-8.
2004: H Haegel-Kronenberger; Krista G Haanstra; C Ziller-Remy; Antonio Ortiz Buijsse; Jan Vermeiren; F Stoeckel; Stefaan W Van Gool; Jan L Ceuppens; Majid Mehtali; Mark de Boer; margreet jonker; Louis Boon
Inhibition of costimulation allows for repeated systemic administration of adenoviral vector in rhesus monkeys.
Gene therapy 2004;11(3):241-52.
2002: Valerie Legrand; Philippe Leissner; Arend Winter; Majid Mehtali; Monika Lusky
Transductional targeting with recombinant adenovirus vectors.
Current gene therapy 2002;2(3):323-39.
2001: Philippe Leissner; Valerie Legrand; Y Schlesinger; DA Hadji; Mark van Raaij; S Cusack; A Pavirani; Majid Mehtali
Influence of adenoviral fiber mutations on viral encapsidation, infectivity and in vivo tropism.
Gene therapy 2001;8(1):49-57.
2001: S Lerondel; Alain Le Pape; C Sené; L Faure; S Bernard; Patrice Diot; ELENA NICOLIS; Majid Mehtali; Monika Lusky; Giulio Cabrini; A Pavirani
Radioisotopic imaging allows optimization of adenovirus lung deposition for cystic fibrosis gene therapy.
Human gene therapy 2001;12(1):1-11.
2000: Kamel Sanhadji; L Grave; Jean-Louis Touraine; Philippe Leissner; C Rouzioux; R Firouzi; L Kehrli; J C Tardy; Majid Mehtali
Gene transfer of anti-gp41 antibody and CD4 immunoadhesin strongly reduces the HIV-1 load in humanized severe combined immunodeficient mice.
AIDS (London, England) 2000;14(18):2813-22.
2000: L Grave; D Dreyer; A Dieterle; P Leroy; AI Michou; C Doderer; A Pavirani; Monika Lusky; Majid Mehtali
Differential influence of the E4 adenoviral genes on viral and cellular promoters.
The journal of gene medicine 2000;2(6):433-43.
2000: Didier Nègre; Philippe-Emmanuel Mangeot; Ghislaine Duisit; S Blanchard; Pierre-Olivier Vidalain; Philippe Leissner; A J Winter; Chantal Rabourdin-Combe; Majid Mehtali; Philippe Moullier; Jean-Luc Darlix; François-Loïc Cosset
Characterization of novel safe lentiviral vectors derived from simian immunodeficiency virus (SIVmac251) that efficiently transduce mature human dendritic cells.
Gene therapy 2000;7(19):1613-23.
2000: Philippe-Emmanuel Mangeot; Didier Nègre; B Dubois; A J Winter; Philippe Leissner; Majid Mehtali; D Kaiserlian; François-Loïc Cosset; Jean-Luc Darlix
Development of minimal lentivirus vectors derived from simian immunodeficiency virus (SIVmac251) and their use for gene transfer into human dendritic cells.
Journal of virology 2000;74(18):8307-15.
2000: Valérie Molinier-Frenkel; H Gahery-Segard; Majid Mehtali; C Le Boulaire; S Ribault; Pierre Boulanger; Thomas Tursz; Jean-Gérard Guillet; Françoise Farace
Immune response to recombinant adenovirus in humans: capsid components from viral input are targets for vector-specific cytotoxic T lymphocytes.
Journal of virology 2000;74(16):7678-82.
2000: Philippe Erbs; Etienne Regulier; J Kintz; P Leroy; Yves Poitevin; Françoise Exinger; Richard Jund; Majid Mehtali
In vivo cancer gene therapy by adenovirus-mediated transfer of a bifunctional yeast cytosine deaminase/uracil phosphoribosyltransferase fusion gene.
Cancer research 2000;60(14):3813-22.
2000: M Christ; B Louis; F Stoeckel; A Dieterle; L Grave; D Dreyer; J Kintz; D Ali Hadji; Monika Lusky; Majid Mehtali
Modulation of the inflammatory properties and hepatotoxicity of recombinant adenovirus vectors by the viral E4 gene products.
Human gene therapy 2000;11(3):415-27.
1999: Francine Puvion-Dutilleul; Valerie Legrand; Majid Mehtali; Mounira K Chelbi-Alix; Hugues de Thé; Edmond Puvion
Deletion of the fiber gene induces the storage of hexon and penton base proteins in PML/Sp100-containing inclusions during adenovirus infection.
Biology of the cell / under the auspices of the European Cell Biology Organization 1999;91(8):617-28.
1999: Monika Lusky; L Grave; A Dieterlé; D Dreyer; M Christ; C Ziller; P Furstenberger; J Kintz; DA Hadji; A Pavirani; Majid Mehtali
Regulation of adenovirus-mediated transgene expression by the viral E4 gene products: requirement for E4 ORF3.
Journal of virology 1999;73(10):8308-19.
1999: George Santis; Valerie Legrand; S S Hong; E Davison; Ian Kirby; J L Imler; R W Finberg; J M Bergelson; Majid Mehtali; Pierre Boulanger
Molecular determinants of adenovirus serotype 5 fibre binding to its cellular receptor CAR.
The Journal of general virology 1999;80 ( Pt 6)():1519-27.
1999: Valerie Legrand; D Spehner; Y Schlesinger; N Settelen; A Pavirani; Majid Mehtali
Fiberless recombinant adenoviruses: virus maturation and infectivity in the absence of fiber.
Journal of virology 1999;73(2):907-19.
1998: P Leroy; Philippe Slos; Horst Homann; Philippe Erbs; Yves Poitevin; Etienne Regulier; F Q Colonna; P Devauchelle; C Roth; A Pavirani; Majid Mehtali
Cancer immunotherapy by direct in vivo transfer of immunomodulatory genes.
Research in immunology 1998;149(7-8):681-4.
1998: Philippe Leissner; V Calenda; M Marigliano; Kamel Sanhadji; J L Touraine; A Pavirani; Majid Mehtali
[In vitro and in vivo inhibition of HIV1 replication by retroviral transfer of interferon alpha, beta, or gamma genes: application to gene therapy of AIDS].
Annales de biologie clinique 1998;56(2):167-73.
1998: Monika Lusky; M Christ; K Rittner; A Dieterle; D Dreyer; B Mourot; H Schultz; F Stoeckel; A Pavirani; Majid Mehtali
In vitro and in vivo biology of recombinant adenovirus vectors with E1, E1/E2A, or E1/E4 deleted.
Journal of virology 1998;72(3):2022-32.
1997: Kamel Sanhadji; Philippe Leissner; R Firouzi; F Pelloquin; L Kehrli; M Marigliano; V Calenda; M Ottmann; J C Tardy; Majid Mehtali; Jean-Louis Touraine
Experimental gene therapy: the transfer of Tat-inducible interferon genes protects human cells against HIV-1 challenge in vitro and in vivo in severe combined immunodeficient mice.
AIDS (London, England) 1997;11(8):977-86.
1997: M Christ; Monika Lusky; F Stoeckel; D Dreyer; A Dieterlé; AI Michou; A Pavirani; Majid Mehtali
Gene therapy with recombinant adenovirus vectors: evaluation of the host immune response.
Immunology letters 1997;57(1-3):19-25.
1997: AI Michou; L Santoro; M Christ; V Julliard; A Pavirani; Majid Mehtali
Adenovirus-mediated gene transfer: influence of transgene, mouse strain and type of immune response on persistence of transgene expression.
Gene therapy 1997;4(5):473-82.
1997: K Rittner; H Schultz; A Pavirani; Majid Mehtali
Conditional repression of the E2 transcription unit in E1-E3-deleted adenovirus vectors is correlated with a strong reduction in viral DNA replication and late gene expression in vitro.
Journal of virology 1997;71(4):3307-11.
1997: AI Michou; M Christ; A Pavirani; Majid Mehtali
[Genetic therapy for hemophiliacs--therapeutic potential and technological limits].
Transfusion clinique et biologique : journal de la Société française de transfusion sanguine 1997;4(3):251-61.
1996: F Quintin-Colonna; Patrick Devauchelle; D Fradelizi; B Mourot; T Faure; Philippe Kourilsky; C Roth; Majid Mehtali
Gene therapy of spontaneous canine melanoma and feline fibrosarcoma by intratumoral administration of histoincompatible cells expressing human interleukin-2.
Gene therapy 1996;3(12):1104-12.
1996: C Chartier; E Degryse; M Gantzer; A Dieterle; A Pavirani; Majid Mehtali
Efficient generation of recombinant adenovirus vectors by homologous recombination in Escherichia coli.
Journal of virology 1996;70(7):4805-10.
1996: V Calenda; Philippe Leissner; M Marigliano; Majid Mehtali
Gene therapy for HIV infection.
Hematology and cell therapy 1996;38(2):211-3.
1996: J L Imler; C Chartier; D Dreyer; A Dieterle; M Sainte-Marie; T Faure; A Pavirani; Majid Mehtali
Novel complementation cell lines derived from human lung carcinoma A549 cells support the growth of E1-deleted adenovirus vectors.
Gene therapy 1996;3(1):75-84.
1995: Ulla rasmussen; Y Schlesinger; A Pavirani; Majid Mehtali
Sequence analysis of the canine adenovirus 2 fiber-encoding gene.
Gene 1995;159(2):279-80.
1995: C S Dunn; Majid Mehtali; L M Houdebine; Jean-Pierre Gut; A Kirn; A M Aubertin
Human immunodeficiency virus type 1 infection of human CD4-transgenic rabbits.
The Journal of general virology 1995;76 ( Pt 6)():1327-36.
1995: J L Imler; C Chartier; A Dieterlé; D Dreyer; Majid Mehtali; A Pavirani
An efficient procedure to select and recover recombinant adenovirus vectors.
Gene therapy 1995;2(4):263-8.
1995: J L Imler; A Bout; D Dreyer; A Dieterlé; H Schultz; Dinko Valerio; Majid Mehtali; A Pavirani
Trans-complementation of E1-deleted adenovirus: a new vector to reduce the possibility of codissemination of wild-type and recombinant adenoviruses.
Human gene therapy 1995;6(6):711-21.
1995: Majid Mehtali; J L Imler; T Sorg; A Pavirani
[Gene therapy for hereditary and acquired human diseases].
Annales d'endocrinologie 1995;56(6):571-4.
1994: Vladimir Liska; Danièle Spehner; Majid Mehtali; D Schmitt; A Kirn; A M Aubertin
Localization of viral protein X in simian immunodeficiency virus macaque strain and analysis of its packaging requirements.
The Journal of general virology 1994;75 ( Pt 11)():2955-62.
1994: Jérôme Estaquier; T Idziorek; F de Bels; F Barré-Sinoussi; Bruno Hurtrel; A M Aubertin; A Venet; Majid Mehtali; E Muchmore; P Michel; Y Mouton; M Girard; Jean-Claude Ameisen
Programmed cell death and AIDS: significance of T-cell apoptosis in pathogenic and nonpathogenic primate lentiviral infections.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(20):9431-5.