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Nicola Baxter

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Yi Jin; Nicola J Baxter; G Michael Blackburn; Matthew Bowler; Matthew J Cliff; Hugh R W Dannatt; Andrea M Hounslow; Jonathan P Waltho
Charge-balanced metal fluoride complexes for protein kinase A with adenosine diphosphate and substrate peptide SP20.
Joanna L Griffin; Andrea M Hounslow; Katherine N Leigh; Nicola J Baxter; G Michael Blackburn; Matthew Bowler; Matthew J Cliff; Hugh R W Dannatt; Charles Edwin Webster; Jonathan P Waltho
Near attack conformers dominate β-phosphoglucomutase complexes where geometry and charge distribution reflect those of substrate.
Liu Xiaoxia; James P Marston; Nicola J Baxter; Andrea M Hounslow; Zhao Yufen; G Michael Blackburn; Matthew J Cliff; Jonathan P Waltho
Prioritization of charge over geometry in transition state analogues of a dual specificity protein kinase.

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All Publications

2012: Yi Jin; Nicola J Baxter; G Michael Blackburn; Matthew Bowler; Matthew J Cliff; Hugh R W Dannatt; Andrea M Hounslow; Jonathan P Waltho
Charge-balanced metal fluoride complexes for protein kinase A with adenosine diphosphate and substrate peptide SP20.
Angewandte Chemie (International ed. in English) 2012;51(49):12242-5.
2012: Joanna L Griffin; Andrea M Hounslow; Katherine N Leigh; Nicola J Baxter; G Michael Blackburn; Matthew Bowler; Matthew J Cliff; Hugh R W Dannatt; Charles Edwin Webster; Jonathan P Waltho
Near attack conformers dominate β-phosphoglucomutase complexes where geometry and charge distribution reflect those of substrate.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(18):6910-5.
2011: Liu Xiaoxia; James P Marston; Nicola J Baxter; Andrea M Hounslow; Zhao Yufen; G Michael Blackburn; Matthew J Cliff; Jonathan P Waltho
Prioritization of charge over geometry in transition state analogues of a dual specificity protein kinase.
Journal of the American Chemical Society 2011;133(11):3989-94.
2010: Matthew J Cliff; Matthew Bowler; Andrea Varga; James P Marston; Judit Szabó; Andrea M Hounslow; Nicola J Baxter; G Michael Blackburn; Mária Vas; Jonathan P Waltho
Transition state analogue structures of human phosphoglycerate kinase establish the importance of charge balance in catalysis.
Journal of the American Chemical Society 2010;132(18):6507-16.
2010: Nicola J Baxter; Matthew Bowler; Tooba Alizadeh; Matthew J Cliff; Andrea M Hounslow; Bin Wu; David B Berkowitz; Nicholas H Williams; G Michael Blackburn; Jonathan P Waltho
Atomic details of near-transition state conformers for enzyme phosphoryl transfer revealed by MgF-3 rather than by phosphoranes.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(10):4555-60.
2009: Nicola J Baxter; Andrea M Hounslow; Matthew Bowler; Nicholas H Williams; G Michael Blackburn; Jonathan P Waltho
MgF(3)(-) and alpha-galactose 1-phosphate in the active site of beta-phosphoglucomutase form a transition state analogue of phosphoryl transfer.
Journal of the American Chemical Society 2009;131(45):16334-5.
2009: Marko Golicnik; Luis F Olguin; Guoqiang Feng; Nicola J Baxter; Jonathan P Waltho; Nicholas H Williams; Florian Hollfelder
Kinetic analysis of beta-phosphoglucomutase and its inhibition by magnesium fluoride.
Journal of the American Chemical Society 2009;131(4):1575-88.
2008: Nicola J Baxter; G Michael Blackburn; James P Marston; Andrea M Hounslow; Matthew J Cliff; Wolfgang Bermel; Nicholas H Williams; Florian Hollfelder; David E Wemmer; Jonathan P Waltho
Anionic charge is prioritized over geometry in aluminum and magnesium fluoride transition state analogs of phosphoryl transfer enzymes.
Journal of the American Chemical Society 2008;130(12):3952-8.
2006: Nicola J Baxter; Luis F Olguin; Marko Golicnik; Guoqiang Feng; Andrea M Hounslow; Wolfgang Bermel; G Michael Blackburn; Florian Hollfelder; Jonathan P Waltho; Nicholas H Williams
A Trojan horse transition state analogue generated by MgF3- formation in an enzyme active site.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(40):14732-7.
2006: Nicola J Baxter; Andreas Roetzer; Hans-Dieter Liebig; Svetlana E Sedelnikova; Andrea M Hounslow; Tim Skern; Jonathan P Waltho
Structure and dynamics of coxsackievirus B4 2A proteinase, an enyzme involved in the etiology of heart disease.
Journal of virology 2006;80(3):1451-62.
2002: Adrian J Charlton; Nicola J Baxter; M Lokman Khan; Arthur J G Moir; Edwin Haslam; Alan P Davies; Michael P Williamson
Polyphenol/peptide binding and precipitation.
Journal of agricultural and food chemistry 2002;50(6):1593-601.
2001: Paul Thaw; Nicola J Baxter; Andrea M Hounslow; C Price; Jonathan P Waltho; C Jeremy Craven
Structure of TCTP reveals unexpected relationship with guanine nucleotide-free chaperones.
Nature structural biology 2001;8(8):701-4.
2000: C Jeremy Craven; Nicola J Baxter; E H Murray; N J Hill; J R Martin; K Ylinenjärvi; Ingemar Björk; Jonathan P Waltho; Iain A Murray
Wild-type and met-65-->Leu variants of human cystatin A are functionally and structurally identical.
Biochemistry 2000;39(51):15783-90.
2000: Nicola J Baxter; Paul Thaw; Lee D Higgins; S E Sedelnikova; A L Bramley; C Price; Jonathan P Waltho; C Jeremy Craven
Backbone NMR assignment of the 19 kDa translationally controlled tumor-associated protein p23fyp from Schizosaccharomyces pombe.
Journal of biomolecular NMR 2000;16(1):83-4.
1999: Laszlo L P Hosszu; Nicola J Baxter; Graham S Jackson; A Power; Anthony R Clarke; Jonathan P Waltho; C Jeremy Craven; John Collinge
Structural mobility of the human prion protein probed by backbone hydrogen exchange.
Nature structural biology 1999;6(8):740-3.
1998: Nicola J Baxter; Laszlo L P Hosszu; Jonathan P Waltho; Michael P Williamson
Characterisation of low free-energy excited states of folded proteins.
Journal of molecular biology 1998;284(5):1625-39.
1997: Nicola J Baxter; Michael P Williamson
Temperature dependence of 1H chemical shifts in proteins.
Journal of biomolecular NMR 1997;9(4):359-69.
1997: Nicola J Baxter; Terence H Lilley; Edwin Haslam; Michael P Williamson
Multiple interactions between polyphenols and a salivary proline-rich protein repeat result in complexation and precipitation.
Biochemistry 1997;36(18):5566-77.
1996: A J Charlton; Nicola J Baxter; T H Lilley; Edwin Haslam; C J McDonald; Michael P Williamson
Tannin interactions with a full-length human salivary proline-rich protein display a stronger affinity than with single proline-rich repeats.
FEBS letters 1996;382(3):289-92.