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Frits Meijlink

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Elvira R M Bakker; Patrick F Franken; Werner Helvensteijn; Ernst J Kuipers; Frits Meijlink; Lalini Raghoebir; Robbert Rottier; Martin A van der Valk; Léon van Gurp; Wendy van Veelen; Ron Smits
Induced Wnt5a expression perturbs embryonic outgrowth and intestinal elongation, but is well-tolerated in adult mice.
Wendy van Veelen; Myrte Theeuwes; Martin A van der Valk; Léon van Gurp; Elvira R M Bakker; Lau Blonden; Riccardo Fodde; Patrick F Franken; Werner Helvensteijn; Ernst J Kuipers; Ngoc H Le; Frits Meijlink; Ron Smits
β-catenin tyrosine 654 phosphorylation increases Wnt signalling and intestinal tumorigenesis.
Cesca van de Ven; Carina Van Rooijen; Teddy Young; Felix Beck; Monika Bialecka; Jean-Noel Freund; Moises Mallo; Frits Meijlink; Roel Neijts; Ana Nóvoa; Jennifer E Rowland; Emma J Stringer; Jacqueline Deschamps
Concerted involvement of Cdx/Hox genes and Wnt signaling in morphogenesis of the caudal neural tube and cloacal derivatives from the posterior growth zone.

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All Publications

2012: Elvira R M Bakker; Patrick F Franken; Werner Helvensteijn; Ernst J Kuipers; Frits Meijlink; Lalini Raghoebir; Robbert Rottier; Martin A van der Valk; Léon van Gurp; Wendy van Veelen; Ron Smits
Induced Wnt5a expression perturbs embryonic outgrowth and intestinal elongation, but is well-tolerated in adult mice.
Developmental biology 2012;369(1):91-100.
2011: Wendy van Veelen; Myrte Theeuwes; Martin A van der Valk; Léon van Gurp; Elvira R M Bakker; Lau Blonden; Riccardo Fodde; Patrick F Franken; Werner Helvensteijn; Ernst J Kuipers; Ngoc H Le; Frits Meijlink; Ron Smits
β-catenin tyrosine 654 phosphorylation increases Wnt signalling and intestinal tumorigenesis.
Gut 2011;60(9):1204-12.
2011: Cesca van de Ven; Carina Van Rooijen; Teddy Young; Felix Beck; Monika Bialecka; Jean-Noel Freund; Moises Mallo; Frits Meijlink; Roel Neijts; Ana Nóvoa; Jennifer E Rowland; Emma J Stringer; Jacqueline Deschamps
Concerted involvement of Cdx/Hox genes and Wnt signaling in morphogenesis of the caudal neural tube and cloacal derivatives from the posterior growth zone.
Development (Cambridge, England) 2011;138(16):3451-62.
2011: Carolien Wansleeben; Petra de Graaf; H Th Marc Timmers; Florence Mousson; Léon van Gurp; Frits Meijlink
An ENU-induced point mutation in the mouse Btaf1 gene causes post-gastrulation embryonic lethality and protein instability.
Mechanisms of development 2011;128(5-6):279-88.
2011: Carolien Wansleeben; Frits Meijlink
The planar cell polarity pathway in vertebrate development.
Developmental dynamics : an official publication of the American Association of Anatomists 2011;240(3):616-26.
2011: Carolien Wansleeben; Léon van Gurp; Harma Feitsma; Carla Kroon; Ester Rieter; Marlies Verberne; Victor Guryev; Edwin Cuppen; Frits Meijlink
An ENU-mutagenesis screen in the mouse: identification of novel developmental gene functions.
PloS one 2011;6(4):e19357.
2011: Daisuke Matsumaru; Ryuma Haraguchi; Shinichi Miyagawa; Jun Motoyama; Naomi Nakagata; Frits Meijlink; Gen Yamada
Genetic analysis of Hedgehog signaling in ventral body wall development and the onset of omphalocele formation.
PloS one 2011;6(1):e16260.
2010: Carolien Wansleeben; Harma Feitsma; Mireille Montcouquiol; Carla Kroon; Edwin Cuppen; Frits Meijlink
Planar cell polarity defects and defective Vangl2 trafficking in mutants for the COPII gene Sec24b.
Development (Cambridge, England) 2010;137(7):1067-73.
2010: Carolien Wansleeben; Harma Feitsma; Leon Tertoolen; Carla Kroon; Victor Guryev; Edwin Cuppen; Frits Meijlink
A novel mutant allele of Ncx1: a single amino acid substitution leads to cardiac dysfunction.
The International journal of developmental biology 2010;54(10):1465-71.
2007: Rüdiger J Blaschke; Nathan D Hahurij; Sanne Kuijper; Steffen Just; Lambertus J Wisse; Kirsten Deissler; Tina Maxelon; Konstantinos Anastassiadis; Jessica Spitzer; Stefan E Hardt; Heinz F Schöler; Harma Feitsma; Wolfgang Rottbauer; Martin Blum; Frits Meijlink; Gudrun Rappold; Adriana C Gittenberger-De Groot
Targeted mutation reveals essential functions of the homeodomain transcription factor Shox2 in sinoatrial and pacemaking development.
Circulation 2007;115(14):1830-8.
2005: Sanne Kuijper; Harma Feitsma; Rushikesh Sheth; Jeroen Korving; Mark Reijnen; Frits Meijlink
Function and regulation of Alx4 in limb development: complex genetic interactions with Gli3 and Shh.
Developmental biology 2005;285(2):533-44.
2005: Sanne Kuijper; Annemiek Beverdam; Carla Kroon; Antje Brouwer; Sophie I Candille; Gregory S Barsh; Frits Meijlink
Genetics of shoulder girdle formation: roles of Tbx15 and aristaless-like genes.
Development (Cambridge, England) 2005;132(7):1601-10.
2004: Tony Oosterveen; Frits Meijlink; Jacqueline Deschamps
Expression of retinaldehyde dehydrogenase II and sequential activation of 5' Hoxb genes in the mouse caudal hindbrain.
Gene expression patterns : GEP 2004;4(3):243-7.
2004: Sophie I Candille; Catherine D van Raamsdonk; Changyou Chen; Sanne Kuijper; Yanru Chen-Tsai; Andreas Russ; Frits Meijlink; Gregory S Barsh
Dorsoventral patterning of the mouse coat by Tbx15.
PLoS biology 2004;2(1):E3.
2003: Tony Oosterveen; Patrick van Vliet; Jacqueline Deschamps; Frits Meijlink
The direct context of a hox retinoic acid response element is crucial for its activity.
The Journal of biological chemistry 2003;278(26):24103-7.
2003: Antje Brouwer; Derk ten Berge; Rob Wiegerinck; Frits Meijlink
The OAR/aristaless domain of the homeodomain protein Cart1 has an attenuating role in vivo.
Mechanisms of development 2003;120(2):241-52.
2003: Tony Oosterveen; Karen Niederreither; Pascal Dollé; Pierre Chambon; Frits Meijlink; Jacqueline Deschamps
Retinoids regulate the anterior expression boundaries of 5' Hoxb genes in posterior hindbrain.
The EMBO journal 2003;22(2):262-9.
2002: Pascal te Welscher; Aimée Zuniga; Sanne Kuijper; Thijs Drenth; Hans J Goedemans; Frits Meijlink; Rolf Zeller
Progression of vertebrate limb development through SHH-mediated counteraction of GLI3.
Science (New York, N.Y.) 2002;298(5594):827-30.
2001: Annemiek Beverdam; Antje Brouwer; Mark Reijnen; Jeroen Korving; Frits Meijlink
Severe nasal clefting and abnormal embryonic apoptosis in Alx3/Alx4 double mutant mice.
Development (Cambridge, England) 2001;128(20):3975-86.
2001: E J van Raaij; Derk ten Berge; W Hage; Antje Brouwer; Frits Meijlink; J B Maintz; FJ Verbeek
Automated topographical cell proliferation analysis.
Cytometry 2001;45(1):13-8.
2001: Annemiek Beverdam; Frits Meijlink
Expression patterns of group-I aristaless-related genes during craniofacial and limb development.
Mechanisms of development 2001;107(1-2):163-7.
2001: Derk ten Berge; Antje Brouwer; Jeroen Korving; Mark Reijnen; E J van Raaij; FJ Verbeek; W Gaffield; Frits Meijlink
Prx1 and Prx2 are upstream regulators of sonic hedgehog and control cell proliferation during mandibular arch morphogenesis.
Development (Cambridge, England) 2001;128(15):2929-38.
1999: Eric van den Akker; Mark Reijnen; Jeroen Korving; Antje Brouwer; Frits Meijlink; Jacqueline Deschamps
Targeted inactivation of Hoxb8 affects survival of a spinal ganglion and causes aberrant limb reflexes.
Mechanisms of development 1999;89(1-2):103-14.
1999: Frits Meijlink; Annemiek Beverdam; Antje Brouwer; Tony Oosterveen; D T Berge
Vertebrate aristaless-related genes.
The International journal of developmental biology 1999;43(7):651-63.
1998: Derk ten Berge; Antje Brouwer; Jeroen Korving; J F Martin; Frits Meijlink
Prx1 and Prx2 in skeletogenesis: roles in the craniofacial region, inner ear and limbs.
Development (Cambridge, England) 1998;125(19):3831-42.
1998: Derk ten Berge; Antje Brouwer; S el Bahi; J L Guénet; B Robert; Frits Meijlink
Mouse Alx3: an aristaless-like homeobox gene expressed during embryogenesis in ectomesenchyme and lateral plate mesoderm.
Developmental biology 1998;199(1):11-25.
1995: Jeroen Charité; Wim de Graaff; R Vogels; Frits Meijlink; Jacqueline Deschamps
Regulation of the Hoxb-8 gene: synergism between multimerized cis-acting elements increases responsiveness to positional information.
Developmental biology 1995;171(2):294-305.
1995: B Leussink; Antje Brouwer; M el Khattabi; Robert E Poelmann; Adriana C Gittenberger-De Groot; Frits Meijlink
Expression patterns of the paired-related homeobox genes MHox/Prx1 and S8/Prx2 suggest roles in development of the heart and the forebrain.
Mechanisms of development 1995;52(1):51-64.
1993: Ron de Jong; J van der Heijden; Frits Meijlink
DNA-binding specificity of the S8 homeodomain.
Nucleic acids research 1993;21(20):4711-20.
1993: Ron de Jong; Frits Meijlink
The homeobox gene S8: mesoderm-specific expression in presomite embryos and in cells cultured in vitro and modulation in differentiating pluripotent cells.
Developmental biology 1993;157(1):133-46.
1993: F Zwartkruis; F Kruyt; Paul T van der Saag; Frits Meijlink
Induction of HOX-2 genes in P19 embryocarcinoma cells is dependent on retinoic acid receptor alpha.
Experimental cell research 1993;205(2):422-5.
1992: Ron de Jong; L de Laaf; H Vennema; Frits Meijlink
DNA-binding activity of the murine homeodomain protein Hox-2.3 produced by a hybrid phage T7/vaccinia virus system.
Gene 1992;116(2):195-203.
1992: F Zwartkruis; T Hoeijmakers; Jacqueline Deschamps; Frits Meijlink
The murine Hox-2.4 promoter contains a functional octamer motif.
Nucleic acids research 1992;20(7):1599-606.
1992: Jacqueline Deschamps; Frits Meijlink
Mammalian homeobox genes in normal development and neoplasia.
Critical reviews in oncogenesis 1992;3(1-2):117-73.
1991: D J Opstelten; R Vogels; B Robert; E Kalkhoven; F Zwartkruis; L de Laaf; Olivier Destrée; Jacqueline Deschamps; K A Lawson; Frits Meijlink
The mouse homeobox gene, S8, is expressed during embryogenesis predominantly in mesenchyme.
Mechanisms of development 1991;34(1):29-41.
1991: F Zwartkruis; T Hoeijmakers; Jacqueline Deschamps; Frits Meijlink
Characterization of the murine Hox-2.3 promoter: involvement of the transcription factor USF (MLTF).
Mechanisms of development 1991;33(3):179-90.
1990: C Kress; R Vogels; Wim de Graaff; Christian Bonnerot; Frits Meijlink; Jean-François Nicolas; Jacqueline Deschamps
Hox-2.3 upstream sequences mediate lacZ expression in intermediate mesoderm derivatives of transgenic mice.
Development (Cambridge, England) 1990;109(4):775-86.
1989: J Noordermeer; Frits Meijlink; P Verrijzer; F Rijsewijk; Olivier Destrée
Isolation of the Xenopus homolog of int-1/wingless and expression during neurula stages of early development.
Nucleic acids research 1989;17(1):11-8.
1988: P Verrijzer; Wim de Graaff; Jacqueline Deschamps; Frits Meijlink
Nucleotide sequence of the Hox2.3 gene region.
Nucleic acids research 1988;16(6):2729.
1987: Frits Meijlink; R de Laaf; P Verrijzer; Olivier Destrée; V Kroezen; J Hilkens; Jacqueline Deschamps
A mouse homeobox containing gene on chromosome 11: sequence and tissue-specific expression.
Nucleic acids research 1987;15(17):6773-86.
1987: Jacqueline Deschamps; R de Laaf; L Joosen; Frits Meijlink; Olivier Destrée
Abundant expression of homeobox genes in mouse embryonal carcinoma cells correlates with chemically induced differentiation.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(5):1304-8.
1987: Jacqueline Deschamps; R de Laaf; P Verrijzer; M de Gouw; Olivier Destrée; Frits Meijlink
The mouse Hox2.3 homeobox-containing gene: regulation in differentiating pluripotent stem cells and expression pattern in embryos.
Differentiation; research in biological diversity 1987;35(1):21-30.
1985: Jacqueline Deschamps; Frits Meijlink; Inder M Verma
Identification of a transcriptional enhancer element upstream from the proto-oncogene fos.
Science (New York, N.Y.) 1985;230(4730):1174-7.
1985: Jacqueline Deschamps; R L Mitchell; Frits Meijlink; Wiebe Kruijer; David Schubert; Inder M Verma
Proto-oncogene fos is expressed during development, differentiation, and growth.
Cold Spring Harbor symposia on quantitative biology 1985;50():733-45.