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Judy Meinkoth

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Xiaoyun Dong; Christopher Korch; Stephen Stopenski; Waixing Tang; Marcia S Brose; Judy L Meinkoth
RAP1GAP inhibits cytoskeletal remodeling and motility in thyroid cancer cells.
Lisa A Vuchak; Oxana M Tsygankova; Judy L Meinkoth
Rap1GAP impairs cell-matrix adhesion in the absence of effects on cell-cell adhesion.
Xiaoyun Dong; Christopher Korch; Judy L Meinkoth
Histone deacetylase inhibitors upregulate Rap1GAP and inhibit Rap activity in thyroid tumor cells.

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All Publications

2012: Xiaoyun Dong; Christopher Korch; Stephen Stopenski; Waixing Tang; Marcia S Brose; Judy L Meinkoth
RAP1GAP inhibits cytoskeletal remodeling and motility in thyroid cancer cells.
Endocrine-related cancer 2012;19(4):575-88.
2011: Lisa A Vuchak; Oxana M Tsygankova; Judy L Meinkoth
Rap1GAP impairs cell-matrix adhesion in the absence of effects on cell-cell adhesion.
Cell adhesion & migration 2011;5(4):323-31.
2011: Xiaoyun Dong; Christopher Korch; Judy L Meinkoth
Histone deacetylase inhibitors upregulate Rap1GAP and inhibit Rap activity in thyroid tumor cells.
Endocrine-related cancer 2011;18(3):301-10.
2010: Oxana M Tsygankova; Changqing Ma; Waixing Tang; Christopher Korch; Michael D Feldman; Yu Lv; Marcia S Brose; Judy L Meinkoth
Downregulation of Rap1GAP in human tumor cells alters cell/matrix and cell/cell adhesion.
Molecular and cellular biology 2010;30(13):3262-74.
2009: Lisa A Vuchak; Oxana M Tsygankova; Gregory V Prendergast; Judy L Meinkoth
Protein kinase A and B-Raf mediate extracellular signal-regulated kinase activation by thyrotropin.
Molecular pharmacology 2009;76(5):1123-9.
2009: Anoma Nellore; Karolina Paziana; Changqing Ma; Oxana M Tsygankova; Yan Wang; Kanchan Puttaswamy; Ammarah U Iqbal; Susanna R Franks; Yu Lv; Andrea B Troxel; Michael D Feldman; Judy L Meinkoth; Marcia S Brose
Loss of Rap1GAP in papillary thyroid cancer.
The Journal of clinical endocrinology and metabolism 2009;94(3):1026-32.
2008: Evgeniya V Smirnova; Therese S Collingwood; Catherine Bisbal; Oxana M Tsygankova; Marina Bogush; Judy L Meinkoth; Earl E Henderson; Roland S Annan; Alexander Y Tsygankov
TULA proteins bind to ABCE-1, a host factor of HIV-1 assembly, and inhibit HIV-1 biogenesis in a UBA-dependent fashion.
Virology 2008;372(1):10-23.
2007: Oxana M Tsygankova; Gregory V Prendergast; Kanchan Puttaswamy; Yan Wang; Michael D Feldman; Hongbin Wang; Marcia S Brose; Judy L Meinkoth
Downregulation of Rap1GAP contributes to Ras transformation.
Molecular and cellular biology 2007;27(19):6647-58.
2006: Aphrothiti J Fikaris; Aurélia E Lewis; Adili Abulaiti; Oxana M Tsygankova; Judy L Meinkoth
Ras triggers ataxia-telangiectasia-mutated and Rad-3-related activation and apoptosis through sustained mitogenic signaling.
The Journal of biological chemistry 2006;281(46):34759-67.
2006: Adili Abulaiti; Aphrothiti J Fikaris; Oxana M Tsygankova; Judy L Meinkoth
Ras induces chromosome instability and abrogation of the DNA damage response.
Cancer research 2006;66(21):10505-12.
2006: Jessica H Dworet; Judy L Meinkoth
Interference with 3',5'-cyclic adenosine monophosphate response element binding protein stimulates apoptosis through aberrant cell cycle progression and checkpoint activation.
Molecular endocrinology (Baltimore, Md.) 2006;20(5):1112-20.
2005: Ademi E Santiago-Walker; Aphrothiti J Fikaris; Gary D Kao; Eric J Brown; Marcelo G Kazanietz; Judy L Meinkoth
Protein kinase C delta stimulates apoptosis by initiating G1 phase cell cycle progression and S phase arrest.
The Journal of biological chemistry 2005;280(37):32107-14.
2005: Cynthia R Ward; Sara E Achenbach; David Holt; Mark E Peterson; Judy L Meinkoth
Thyrotropin-stimulated DNA synthesis and thyroglobulin expression in normal and hyperthyroid feline thyrocytes in monolayer culture.
Thyroid : official journal of the American Thyroid Association 2005;15(2):114-20.
2004: Aurélia E Lewis; Aphrothiti J Fikaris; Gregory V Prendergast; Judy L Meinkoth
Thyrotropin and serum regulate thyroid cell proliferation through differential effects on p27 expression and localization.
Molecular endocrinology (Baltimore, Md.) 2004;18(9):2321-32.
2004: Oxana M Tsygankova; Elena Feshchenko; Peter S Klein; Judy L Meinkoth
Thyroid-stimulating hormone/cAMP and glycogen synthase kinase 3beta elicit opposing effects on Rap1GAP stability.
The Journal of biological chemistry 2004;279(7):5501-7.
2004: Nadia Gurvich; Oxana M Tsygankova; Judy L Meinkoth; Peter S Klein
Histone deacetylase is a target of valproic acid-mediated cellular differentiation.
Cancer research 2004;64(3):1079-86.
2004: Judy L Meinkoth
Biology of Ras in thyroid cells.
Cancer treatment and research 2004;122():131-48.
2003: Hong Lin; Jinbin Zhai; Zhenying Nie; Junhua Wu; Judy L Meinkoth; William W Schlaepfer; Rafaela Cañete-Soler
Neurofilament RNA causes neurodegeneration with accumulation of ubiquitinated aggregates in cultured motor neurons.
Journal of neuropathology and experimental neurology 2003;62(9):936-50.
2003: Yiwen Li; Marco I Gonzalez; Judy L Meinkoth; Jeffrey Field; Marcelo G Kazanietz; Gihan I. Tennekoon
Lysophosphatidic acid promotes survival and differentiation of rat Schwann cells.
The Journal of biological chemistry 2003;278(11):9585-91.
2003: Guanjun Cheng; Aurélia E Lewis; Judy L Meinkoth
Ras stimulates aberrant cell cycle progression and apoptosis in rat thyroid cells.
Molecular endocrinology (Baltimore, Md.) 2003;17(3):450-9.
2002: Fang C Mei; Jingbo Qiao; Oxana M Tsygankova; Judy L Meinkoth; Lawrence A Quilliam; Xiaodong Cheng
Differential signaling of cyclic AMP: opposing effects of exchange protein directly activated by cyclic AMP and cAMP-dependent protein kinase on protein kinase B activation.
The Journal of biological chemistry 2002;277(13):11497-504.
2002: Arturo P Saavedra; Oxana M Tsygankova; Gregory V Prendergast; Jessica H Dworet; Guanjun Cheng; Judy L Meinkoth
Role of cAMP, PKA and Rap1A in thyroid follicular cell survival.
Oncogene 2002;21(5):778-88.
2001: Guanjun Cheng; Judy L Meinkoth
Enhanced sensitivity to apoptosis in Ras-transformed thyroid cells.
Oncogene 2001;20(50):7334-41.
2001: Oxana M Tsygankova; Arturo P Saavedra; John F Rebhun; Lawrence A Quilliam; Judy L Meinkoth
Coordinated regulation of Rap1 and thyroid differentiation by cyclic AMP and protein kinase A.
Molecular and cellular biology 2001;21(6):1921-9.
2000: Oxana M Tsygankova; E Kupperman; W Wen; Judy L Meinkoth
Cyclic AMP activates Ras.
Oncogene 2000;19(32):3609-15.
2000: LA Cass; Judy L Meinkoth
Ras signaling through PI3K confers hormone-independent proliferation that is compatible with differentiation.
Oncogene 2000;19(7):924-32.
2000: Arturo P Saavedra; LA Cass; Gregory V Prendergast; Judy L Meinkoth
Differential effects of acute and chronic exposure to interferon-gamma on cyclic adenosine 3',5'-monophosphate response element-regulated gene expression.
Endocrinology 2000;141(2):606-14.
2000: N Fernandez; Maria Jose Caloca; Gregory V Prendergast; Judy L Meinkoth; Marcelo G Kazanietz
Atypical protein kinase C-zeta stimulates thyrotropin-independent proliferation in rat thyroid cells.
Endocrinology 2000;141(1):146-52.
1999: LA Cass; SA Summers; Gregory V Prendergast; Jonathan M Backer; Morris J Birnbaum; Judy L Meinkoth
Protein kinase A-dependent and -independent signaling pathways contribute to cyclic AMP-stimulated proliferation.
Molecular and cellular biology 1999;19(9):5882-91.
1998: P Kunapuli; John A Lawson; Joshua Rokach; Judy L Meinkoth; garret fitzgerald
Prostaglandin F2alpha (PGF2alpha) and the isoprostane, 8, 12-iso-isoprostane F2alpha-III, induce cardiomyocyte hypertrophy. Differential activation of downstream signaling pathways.
The Journal of biological chemistry 1998;273(35):22442-52.
1998: M J Miller; Lise Rioux; Gregory V Prendergast; S Cannon; M A White; Judy L Meinkoth
Differential effects of protein kinase A on Ras effector pathways.
Molecular and cellular biology 1998;18(7):3718-26.
1998: LA Cass; Judy L Meinkoth
Differential effects of cyclic adenosine 3',5'-monophosphate on p70 ribosomal S6 kinase.
Endocrinology 1998;139(4):1991-8.
1997: M J Miller; Sally A Prigent; E Kupperman; Lise Rioux; S H Park; J R Feramisco; M A White; JL Rutkowski; Judy L Meinkoth
RalGDS functions in Ras- and cAMP-mediated growth stimulation.
The Journal of biological chemistry 1997;272(9):5600-5.
1996: Walter Kolch; A Philipp; Mischak Harald; E M Dutil; TM Mullen; James R Feramisco; Judy L Meinkoth; David W Rose
Inhibition of Raf-1 signaling by a monoclonal antibody, which interferes with Raf-1 activation and with Mek substrate binding.
Oncogene 1996;13(6):1305-14.
1996: E Kupperman; D Wofford; W Wen; Judy L Meinkoth
Ras inhibits thyroglobulin expression but not cyclic adenosine monophosphate-mediated signaling in Wistar rat thyrocytes.
Endocrinology 1996;137(1):96-104.
1995: W Wen; Judy L Meinkoth; Roger Y Tsien; Susan S Taylor
Identification of a signal for rapid export of proteins from the nucleus.
Cell 1995;82(3):463-73.
1995: B H Jhun; T Haruta; Judy L Meinkoth; W Leitner; Boris Draznin; Alan Saltiel; L Pang; Toshiyasu Sasaoka; Jerrold M Olefsky
Signal transduction pathways leading to insulin-induced early gene induction.
Biochemistry 1995;34(25):7996-8004.
1995: Renate B Pilz; Modem Suhasini; S Idriss; Judy L Meinkoth; Gerry R Boss
Nitric oxide and cGMP analogs activate transcription from AP-1-responsive promoters in mammalian cells.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1995;9(7):552-8.
1995: R Armstrong; W Wen; Judy L Meinkoth; S Taylor; Marc Montminy
A refractory phase in cyclic AMP-responsive transcription requires down regulation of protein kinase A.
Molecular and cellular biology 1995;15(3):1826-32.
1995: N al-Alawi; David Rose; C Buckmaster; N Ahn; U Rapp; Judy L Meinkoth; James R Feramisco
Thyrotropin-induced mitogenesis is Ras dependent but appears to bypass the Raf-dependent cytoplasmic kinase cascade.
Molecular and cellular biology 1995;15(3):1162-8.
1995: W Wen; Susan S Taylor; Judy L Meinkoth
The expression and intracellular distribution of the heat-stable protein kinase inhibitor is cell cycle regulated.
The Journal of biological chemistry 1995;270(5):2041-6.
1994: W Wen; A T Harootunian; S R Adams; James R Feramisco; Roger Y Tsien; Judy L Meinkoth; Susan S Taylor
Heat-stable inhibitors of cAMP-dependent protein kinase carry a nuclear export signal.
The Journal of biological chemistry 1994;269(51):32214-20.
1994: T Tominaga; J Dela Cruz; G N Burrow; Judy L Meinkoth
Divergent patterns of immediate early gene expression in response to thyroid-stimulating hormone and insulin-like growth factor I in Wistar rat thyrocytes.
Endocrinology 1994;135(3):1212-9.
1994: B H Jhun; Judy L Meinkoth; J W Leitner; Boris Draznin; Jerrold M Olefsky
Insulin and insulin-like growth factor-I signal transduction requires p21ras.
The Journal of biological chemistry 1994;269(8):5699-704.
1994: D A Fantozzi; A T Harootunian; W Wen; Susan S Taylor; James R Feramisco; Roger Y Tsien; Judy L Meinkoth
Thermostable inhibitor of cAMP-dependent protein kinase enhances the rate of export of the kinase catalytic subunit from the nucleus.
The Journal of biological chemistry 1994;269(4):2676-86.
1993: Judy L Meinkoth; ARTHUR S ALBERTS; W Went; D Fantozzi; Susan S Taylor; M Hagiwara; M Montminy; James R Feramisco
Signal transduction through the cAMP-dependent protein kinase.
Molecular and cellular biochemistry 1993;127-128():179-86.
1993: A T Harootunian; S R Adams; W Wen; Judy L Meinkoth; Susan S Taylor; Roger Y Tsien
Movement of the free catalytic subunit of cAMP-dependent protein kinase into and out of the nucleus can be explained by diffusion.
Molecular biology of the cell 1993;4(10):993-1002.
1993: S M Sorscher; P Steeg; James R Feramisco; C Buckmaster; Gerry R Boss; Judy L Meinkoth
Microinjection of an nm23 specific antibody inhibits cell division in rat embryo fibroblasts.
Biochemical and biophysical research communications 1993;195(1):336-45.
1993: E Kupperman; W Wen; Judy L Meinkoth
Inhibition of thyrotropin-stimulated DNA synthesis by microinjection of inhibitors of cellular Ras and cyclic AMP-dependent protein kinase.
Molecular and cellular biology 1993;13(8):4477-84.
1993: ARTHUR S ALBERTS; T Deng; A Lin; Judy L Meinkoth; Axel H Schönthal; Marc C Mumby; Michael Karin; James R Feramisco
Protein phosphatase 2A potentiates activity of promoters containing AP-1-binding elements.
Molecular and cellular biology 1993;13(4):2104-12.
1992: D A Fantozzi; Susan S Taylor; Paul W Howard; Richard A Maurer; James R Feramisco; Judy L Meinkoth
Effect of the thermostable protein kinase inhibitor on intracellular localization of the catalytic subunit of cAMP-dependent protein kinase.
The Journal of biological chemistry 1992;267(24):16824-8.
1992: S Sorscher; J Lillienau; Judy L Meinkoth; Joseph H Steinbach; Claudio D Schteingart; James R Feramisco; Alan F Hofmann
Conjugated bile acid uptake by Xenopus laevis oocytes induced by microinjection with ileal Poly A+ mRNA.
Biochemical and biophysical research communications 1992;186(3):1455-62.
1992: M Hagiwara; ARTHUR S ALBERTS; Paul K Brindle; Judy L Meinkoth; James R Feramisco; T Deng; Michael Karin; Shirish Shenolikar; Marc Montminy
Transcriptional attenuation following cAMP induction requires PP-1-mediated dephosphorylation of CREB.
Cell 1992;70(1):105-13.
1992: Judy L Meinkoth; P K Goldsmith; Allen Spiegel; James R Feramisco; G N Burrow
Inhibition of thyrotropin-induced DNA synthesis in thyroid follicular cells by microinjection of an antibody to the stimulatory G protein of adenylate cyclase, Gs.
The Journal of biological chemistry 1992;267(19):13239-45.
1992: V J LaMorte; P K Goldsmith; Allen Spiegel; Judy L Meinkoth; James R Feramisco
Inhibition of DNA synthesis in living cells by microinjection of Gi2 antibodies.
The Journal of biological chemistry 1992;267(2):691-4.
1991: Judy L Meinkoth; J Dela Cruz; G N Burrow
TSH, IGF-1 and activated ras protein induce DNA synthesis in cultured thyroid cells.
Thyroidology / A.P.R.I.M 1991;3(3):103-7.