Eisuke Mekada

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Chemicals & Drugs

Living Beings

Anatomy

Physiology

Sign-in to see full Profile

Sign-in to see all Coauthors

Publications

TOP 3
Yagi Hiroshi; Yotsumoto Fusanori; Sonoda Kenzo; Kuroki Masahide; Mekada Eisuke; Miyamoto Shingo
Synergistic anti-tumor effect of paclitaxel with CRM197, an inhibitor of HB-EGF, in ovarian cancer.
Miyado Kenji; Yoshida Keiichi; Yamagata Kazuo; Sakakibara Keiichi; Okabe Masaru; Wang Xiaobiao; Miyamoto Kiyoko; Akutsu Hidenori; Kondo Takahiko; Takahashi Yuji; Ban Tadanobu; Ito Chizuru; Toshimori Kiyotaka; Nakamura Akihiro; Ito Masahiko; Miyado Mami; Mekada Eisuke; Umezawa Akihiro
The fusing ability of sperm is bestowed by CD9-containing vesicles released from eggs in mice.
Takeda Yoshito; He Ping; Tachibana Isao; Zhou Bo; Miyado Kenji; Kaneko Hideshi; Suzuki Mayumi; Minami Seigo; Iwasaki Takeo; Goya Sho; Kijima Takashi; Kumagai Toru; Yoshida Mitsuhiro; Osaki Tadashi; Komori Toshihisa; Mekada Eisuke; Kawase Ichiro
Double deficiency of tetraspanins CD9 and CD81 alters cell motility and protease production of macrophages and causes chronic obstructive pulmonary disease-like phenotype in mice.

Sign-in to see all Publications

Sign in free and see...

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the visualized research activity
of experts around the globe

Sign-in to see more

Geonetwork of Eisuke Mekada (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

Sign-in to see more

All Publications

2009: Yagi Hiroshi; Yotsumoto Fusanori; Sonoda Kenzo; Kuroki Masahide; Mekada Eisuke; Miyamoto Shingo
Synergistic anti-tumor effect of paclitaxel with CRM197, an inhibitor of HB-EGF, in ovarian cancer.
International journal of cancer. Journal international du cancer 2009;124(6):1429-39.
2008: Miyado Kenji; Yoshida Keiichi; Yamagata Kazuo; Sakakibara Keiichi; Okabe Masaru; Wang Xiaobiao; Miyamoto Kiyoko; Akutsu Hidenori; Kondo Takahiko; Takahashi Yuji; Ban Tadanobu; Ito Chizuru; Toshimori Kiyotaka; Nakamura Akihiro; Ito Masahiko; Miyado Mami; Mekada Eisuke; Umezawa Akihiro
The fusing ability of sperm is bestowed by CD9-containing vesicles released from eggs in mice.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(35):12921-6.
2008: Takeda Yoshito; He Ping; Tachibana Isao; Zhou Bo; Miyado Kenji; Kaneko Hideshi; Suzuki Mayumi; Minami Seigo; Iwasaki Takeo; Goya Sho; Kijima Takashi; Kumagai Toru; Yoshida Mitsuhiro; Osaki Tadashi; Komori Toshihisa; Mekada Eisuke; Kawase Ichiro
Double deficiency of tetraspanins CD9 and CD81 alters cell motility and protease production of macrophages and causes chronic obstructive pulmonary disease-like phenotype in mice.
The Journal of biological chemistry 2008;283(38):26089-97.
2008: Minami Seigo; Iwamoto Ryo; Mekada Eisuke
HB-EGF decelerates cell proliferation synergistically with TGFalpha in perinatal distal lung development.
Developmental dynamics : an official publication of the American Association of Anatomists 2008;237(1):247-58.
2008: Yotsumoto Fusanori; Yagi Hiroshi; Suzuki Satoshi O; Oki Eiji; Tsujioka Hiroshi; Hachisuga Touru; Sonoda Kenzo; Kawarabayashi Tatsuhiko; Mekada Eisuke; Miyamoto Shingo
Validation of HB-EGF and amphiregulin as targets for human cancer therapy.
Biochemical and biophysical research communications 2008;365(3):555-61.
2008: Tanigawa Maya; Miyamoto Kiyoko; Kobayashi Satoshi; Sato Masahiro; Akutsu Hidenori; Okabe Masaru; Mekada Eisuke; Sakakibara Keiichi; Miyado Mami; Umezawa Akihiro; Miyado Kenji
Possible involvement of CD81 in acrosome reaction of sperm in mice.
Molecular reproduction and development 2008;75(1):150-5.
2008: Miyamoto Shingo; Yagi Hiroshi; Yotsumoto Fusanori; Kawarabayashi Tatsuhiko; Mekada Eisuke
Heparin-binding epidermal growth factor-like growth factor as a new target molecule for cancer therapy.
Advances in experimental medicine and biology 2008;622():281-95.
2007: Xie Huirong; Wang Haibin; Tranguch Susanne; Iwamoto Ryo; Mekada Eisuke; Demayo Francesco J; Lydon John P; Das Sanjoy K; Dey Sudhansu K
Maternal heparin-binding-EGF deficiency limits pregnancy success in mice.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(46):18315-20.
2007: Miyamoto Shingo; Yagi Hiroshi; Yotsumoto Fusanori; Horiuchi Shinji; Yoshizato Toshiyuki; Kawarabayashi Tatsuhiko; Kuroki Masahide; Mekada Eisuke
New approach to cancer therapy: heparin binding-epidermal growth factor-like growth factor as a novel targeting molecule.
Anticancer research 2007;27(6A):3713-21.
2007: Oki Shinya; Hashimoto Ryuju; Okui Yuko; Shen Michael M; Mekada Eisuke; Otani Hiroki; Saijoh Yukio; Hamada Hiroshi
Sulfated glycosaminoglycans are necessary for Nodal signal transmission from the node to the left lateral plate in the mouse embryo.
Development (Cambridge, England) 2007;134(21):3893-904.
2007: Sonoda Kenzo; Miyamoto Shingo; Yamazaki Ayano; Kobayashi Hiroaki; Nakashima Manabu; Mekada Eisuke; Wake Norio
Biologic significance of receptor-binding cancer antigen expressed on SiSo cells (RCAS1) as a pivotal regulator of tumor growth through angiogenesis in human uterine cancer.
Cancer 2007;110(9):1979-90.
2007: Kageyama Takuya; Ohishi Minako; Miyamoto Shingo; Mizushima Hiroto; Iwamoto Ryo; Mekada Eisuke
Diphtheria toxin mutant CRM197 possesses weak EF2-ADP-ribosyl activity that potentiates its anti-tumorigenic activity.
Journal of biochemistry 2007;142(1):95-104.
2007: Katayama Hideki; Kusaka Yoshitomo; Yokota Haruo; Akao Tetsuyuki; Kojima Masayasu; Nakamura Osamu; Mekada Eisuke; Mizuki Eiich
Parasporin-1, a novel cytotoxic protein from Bacillus thuringiensis, induces Ca2+ influx and a sustained elevation of the cytoplasmic Ca2+ concentration in toxin-sensitive cells.
The Journal of biological chemistry 2007;282(10):7742-52.
2006: Nanba Daisuke; Kinugasa Yumi; Morimoto Chie; Koizumi Michiko; Yamamura Hisako; Takahashi Katsuhito; Takakura Nobuyuki; Mekada Eisuke; Hashimoto Koji; Higashiyama Shigeki
Loss of HB-EGF in smooth muscle or endothelial cell lineages causes heart malformation.
Biochemical and biophysical research communications 2006;350(2):315-21.
2006: Miyamoto Shingo; Yagi Hiroshi; Yotsumoto Fusanori; Kawarabayashi Tatsuhiko; Mekada Eisuke
Heparin-binding epidermal growth factor-like growth factor as a novel targeting molecule for cancer therapy.
Cancer science 2006;97(5):341-7.
2006: Kakumoto Kyoko; Sasai Ken; Sukezane Taiko; Oneyama Chitose; Ishimaru Satoshi; Shibutani Kana; Mizushima Hiroto; Mekada Eisuke; Hanafusa Hidesaburo; Akagi Tsuyoshi
FRA1 is a determinant for the difference in RAS-induced transformation between human and rat fibroblasts.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(14):5490-5.
2006: Wang Xiaobiao; Mizushima Hiroto; Adachi Satoshi; Ohishi Minako; Iwamoto Ryo; Mekada Eisuke
Cytoplasmic domain phosphorylation of heparin-binding EGF-like growth factor.
Cell structure and function 2006;31(1):15-27.
2006: Iwamoto Ryo; Mekada Eisuke
ErbB and HB-EGF signaling in heart development and function.
Cell structure and function 2006;31(1):1-14.
2005: Mine Naoki; Iwamoto Ryo; Mekada Eisuke
HB-EGF promotes epithelial cell migration in eyelid development.
Development (Cambridge, England) 2005;132(19):4317-26.
2005: Tanaka Yoshihiro; Miyamoto Shingo; Suzuki Satoshi O; Oki Eiji; Yagi Hiroshi; Sonoda Kenzo; Yamazaki Ayano; Mizushima Hiroto; Maehara Yoshihiko; Mekada Eisuke; Nakano Hitoo
Clinical significance of heparin-binding epidermal growth factor-like growth factor and a disintegrin and metalloprotease 17 expression in human ovarian cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(13):4783-92.
2005: Shirakata Yuji; Kimura Rina; Nanba Daisuke; Iwamoto Ryo; Tokumaru Sho; Morimoto Chie; Yokota Koichi; Nakamura Masanori; Sayama Koji; Mekada Eisuke; Higashiyama Shigeki; Hashimoto Koji
Heparin-binding EGF-like growth factor accelerates keratinocyte migration and skin wound healing.
Journal of cell science 2005;118(Pt 11):2363-70.
2005: Yagi H; Miyamoto S; Tanaka Y; Sonoda K; Kobayashi H; Kishikawa T; Iwamoto R; Mekada E; Nakano H
Clinical significance of heparin-binding epidermal growth factor-like growth factor in peritoneal fluid of ovarian cancer.
British journal of cancer 2005;92(9):1737-45.
2005: Katayama Hideki; Yokota Haruo; Akao Tetsuyuki; Nakamura Osamu; Ohba Michio; Mekada Eisuke; Mizuki Eiichi
Parasporin-1, a novel cytotoxic protein to human cells from non-insecticidal parasporal inclusions of Bacillus thuringiensis.
Journal of biochemistry 2005;137(1):17-25.
2005: Kimura Rina; Iwamoto Ryo; Mekada Eisuke
Soluble form of heparin-binding EGF-like growth factor contributes to retinoic acid-induced epidermal hyperplasia.
Cell structure and function 2005;30(2):35-42.
2004: Takazaki Risa; Shishido Yuji; Iwamoto Ryo; Mekada Eisuke
Suppression of the biological activities of the epidermal growth factor (EGF)-like domain by the heparin-binding domain of heparin-binding EGF-like Growth Factor.
The Journal of biological chemistry 2004;279(45):47335-43.
2004: Miyamoto Shingo; Mekada Eisuke
[Biological behavior of ovarian cancer]
Nippon rinsho. Japanese journal of clinical medicine 2004;62 Suppl 10():458-62.
2004: Moribe Hiroki; Yochem John; Yamada Hiromi; Tabuse Yo; Fujimoto Toyoshi; Mekada Eisuke
Tetraspanin protein (TSP-15) is required for epidermal integrity in Caenorhabditis elegans.
Journal of cell science 2004;117(Pt 22):5209-20.
2004: Miyamoto Shingo; Hirata Michinari; Yamazaki Ayano; Kageyama Takuya; Hasuwa Hidetoshi; Mizushima Hiroto; Tanaka Yoshihiro; Yagi Hiroshi; Sonoda Kenzo; Kai Masahiro; Kanoh Hideo; Nakano Hitoo; Mekada Eisuke
Heparin-binding EGF-like growth factor is a promising target for ovarian cancer therapy.
Cancer research 2004;64(16):5720-7.
2004: Ishibashi Tomoko; Ding Lei; Ikenaka Kazuhiro; Inoue Yoshiro; Miyado Kenji; Mekada Eisuke; Baba Hiroko
Tetraspanin protein CD9 is a novel paranodal component regulating paranodal junctional formation.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004;24(1):96-102.
2003: Yamazaki Satoru; Iwamoto Ryo; Saeki Kazuko; Asakura Masanori; Takashima Seiji; Yamazaki Ayano; Kimura Rina; Mizushima Hiroto; Moribe Hiroki; Higashiyama Shigeki; Endoh Masayuki; Kaneda Yasufumi; Takagi Satoshi; Itami Satoshi; Takeda Naoki; Yamada Gen; Mekada Eisuke
Mice with defects in HB-EGF ectodomain shedding show severe developmental abnormalities.
The Journal of cell biology 2003;163(3):469-75.
2003: Takeda Yoshito; Tachibana Isao; Miyado Kenji; Kobayashi Masatoshi; Miyazaki Toru; Funakoshi Toshiki; Kimura Hiromi; Yamane Hiroyuki; Saito Yoshiyuki; Goto Hiroyuki; Yoneda Tsutomu; Yoshida Mitsuhiro; Kumagai Toru; Osaki Tadashi; Hayashi Seiji; Kawase Ichiro; Mekada Eisuke
Tetraspanins CD9 and CD81 function to prevent the fusion of mononuclear phagocytes.
The Journal of cell biology 2003;161(5):945-56.
2003: Takenobu Hisanori; Yamazaki Ayano; Hirata Michinari; Umata Toshiyuki; Mekada Eisuke
The stress- and inflammatory cytokine-induced ectodomain shedding of heparin-binding epidermal growth factor-like growth factor is mediated by p38 MAPK, distinct from the 12-O-tetradecanoylphorbol-13-acetate- and lysophosphatidic acid-induced signaling cascades.
The Journal of biological chemistry 2003;278(19):17255-62.
2003: Fujita Takuji; Miyamoto Shingo; Onoyama Ichiro; Sonoda Kenzo; Mekada Eisuke; Nakano Hitoo
Expression of lysophosphatidic acid receptors and vascular endothelial growth factor mediating lysophosphatidic acid in the development of human ovarian cancer.
Cancer letters 2003;192(2):161-9.
2003: Iwamoto Ryo; Yamazaki Satoru; Asakura Masanori; Takashima Seiji; Hasuwa Hidetoshi; Miyado Kenji; Adachi Satoshi; Kitakaze Masafumi; Hashimoto Koji; Raab Gerhard; Nanba Daisuke; Higashiyama Shigeki; Hori Masatsugu; Klagsbrun Michael; Mekada Eisuke
Heparin-binding EGF-like growth factor and ErbB signaling is essential for heart function.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(6):3221-6.
2002: Kawashima Masatou; Doh-ura Katsumi; Mekada Eisuke; Fukui Masashi; Iwaki Toru
CD9 expression in solid non-neuroepithelial tumors and infiltrative astrocytic tumors.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2002;50(9):1195-203.
2002: Yu Xiaochun; Sharma Kailash D; Takahashi Tsuyoshi; Iwamoto Ryo; Mekada Eisuke
Ligand-independent dimer formation of epidermal growth factor receptor (EGFR) is a step separable from ligand-induced EGFR signaling.
Molecular biology of the cell 2002;13(7):2547-57.
2002: Shimizu Toko; Matsuishi Toyojiro; Iwamoto Ryo; Handa Kazuyo; Yoshioka Hiroshi; Kato Hirohisa; Ueda Shigeharu; Hara Hideo; Tabira Takeshi; Mekada Eisuke
Elevated levels of anti-CD9 antibodies in the cerebrospinal fluid of patients with subacute sclerosing panencephalitis.
The Journal of infectious diseases 2002;185(9):1346-50.
2001: Hasuwa H; Shishido Y; Yamazaki A; Kobayashi T; Yu X; Mekada E
CD9 amino acids critical for upregulation of diphtheria toxin binding.
Biochemical and biophysical research communications 2001;289(4):782-90.
2001: Miyamoto S; Maruyama A; Okugawa K; Akazawa K; Baba H; Maehara Y; Mekada E
Loss of motility-related protein 1 (MRP1/CD9) and integrin alpha3 expression in endometrial cancers.
Cancer 2001;92(3):542-8.
2001: Umata T; Hirata M; Takahashi T; Ryu F; Shida S; Takahashi Y; Tsuneoka M; Miura Y; Masuda M; Horiguchi Y; Mekada E
A dual signaling cascade that regulates the ectodomain shedding of heparin-binding epidermal growth factor-like growth factor.
The Journal of biological chemistry 2001;276(32):30475-82.
2001: Hirata M; Umata T; Takahashi T; Ohnuma M; Miura Y; Iwamoto R; Mekada E
Identification of serum factor inducing ectodomain shedding of proHB-EGF and sStudies of noncleavable mutants of proHB-EGF.
Biochemical and biophysical research communications 2001;283(4):915-22.
2001: Nakamura Y; Handa K; Iwamoto R; Tsukamoto T; Takahasi M; Mekada E
Immunohistochemical distribution of CD9, heparin binding epidermal growth factor-like growth factor, and integrin alpha3beta1 in normal human tissues.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2001;49(4):439-44.
2001: Takahashi T; Umata T; Mekada E
Extension of juxtamembrane domain of diphtheria toxin receptor arrests translocation of diphtheria toxin fragment A into cytosol.
Biochemical and biophysical research communications 2001;281(3):690-6.
2001: Kusukawa J; Ryu F; Kameyama T; Mekada E
Reduced expression of CD9 in oral squamous cell carcinoma: CD9 expression inversely related to high prevalence of lymph node metastasis.
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2001;30(2):73-9.
2000: Baba I; Shirasawa S; Iwamoto R; Okumura K; Tsunoda T; Nishioka M; Fukuyama K; Yamamoto K; Mekada E; Sasazuki T
Involvement of deregulated epiregulin expression in tumorigenesis in vivo through activated Ki-Ras signaling pathway in human colon cancer cells.
Cancer research 2000;60(24):6886-9.
2000: Suzuki H; Okazawa Y; Komiya T; Saeki K; Mekada E; Kitada S; Ito A; Mihara K
Characterization of rat TOM40, a central component of the preprotein translocase of the mitochondrial outer membrane.
The Journal of biological chemistry 2000;275(48):37930-6.
2000: Iwamoto R; Mekada E
Heparin-binding EGF-like growth factor: a juxtacrine growth factor.
Cytokine & growth factor reviews 2000;11(4):335-44.
2000: Ryu F; Takahashi T; Nakamura K; Takahashi Y; Kobayashi T; Shida S; Kameyama T; Mekada E
Domain analysis of the tetraspanins: studies of CD9/CD63 chimeric molecules on subcellular localization and upregulation activity for diphtheria toxin binding.
Cell structure and function 2000;25(5):317-27.
2000: Saeki K; Suzuki H; Tsuneoka M; Maeda M; Iwamoto R; Hasuwa H; Shida S; Takahashi T; Sakaguchi M; Endo T; Miura Y; Mekada E; Mihara K
Identification of mammalian TOM22 as a subunit of the preprotein translocase of the mitochondrial outer membrane.
The Journal of biological chemistry 2000;275(41):31996-2002.
2000: Doh-ura K; Mekada E; Ogomori K; Iwaki T
Enhanced CD9 expression in the mouse and human brains infected with transmissible spongiform encephalopathies.
Journal of neuropathology and experimental neurology 2000;59(9):774-85.
2000: Miyado K; Mekada E; Kobayashi K
[A crucial role of tetraspanin, CD9 in fertilization]
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 2000;45(10):1728-34.
2000: Yu X; Miyamoto S; Mekada E
Integrin alpha 2 beta 1-dependent EGF receptor activation at cell-cell contact sites.
Journal of cell science 2000;113 ( Pt 12)():2139-47.
2000: Nakamura K; Mitamura T; Takahashi T; Kobayashi T; Mekada E
Importance of the major extracellular domain of CD9 and the epidermal growth factor (EGF)-like domain of heparin-binding EGF-like growth factor for up-regulation of binding and activity.
The Journal of biological chemistry 2000;275(24):18284-90.
2000: Tsuneoka M; Mekada E
Ras/MEK signaling suppresses Myc-dependent apoptosis in cells transformed by c-myc and activated ras.
Oncogene 2000;19(1):115-23.
2000: Miyado K; Yamada G; Yamada S; Hasuwa H; Nakamura Y; Ryu F; Suzuki K; Kosai K; Inoue K; Ogura A; Okabe M; Mekada E
Requirement of CD9 on the egg plasma membrane for fertilization.
Science (New York, N.Y.) 2000;287(5451):321-4.
1999: Iwamoto R; Handa K; Mekada E
Contact-dependent growth inhibition and apoptosis of epidermal growth factor (EGF) receptor-expressing cells by the membrane-anchored form of heparin-binding EGF-like growth factor.
The Journal of biological chemistry 1999;274(36):25906-12.
1998: Izumi Y; Hirata M; Hasuwa H; Iwamoto R; Umata T; Miyado K; Tamai Y; Kurisaki T; Sehara-Fujisawa A; Ohno S; Mekada E
A metalloprotease-disintegrin, MDC9/meltrin-gamma/ADAM9 and PKCdelta are involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor.
The EMBO journal 1998;17(24):7260-72.
1998: Tsuneoka M; Mekada E
N-myc transactivates RCC1 gene expression in rat fibroblast cells transformed by N-myc and v-ras.
Journal of biochemistry 1998;124(5):1013-9.
1998: Umata T; Mekada E
Diphtheria toxin translocation across endosome membranes. A novel cell permeabilization assay reveals new diphtheria toxin fragments in endocytic vesicles.
The Journal of biological chemistry 1998;273(14):8351-9.
1997: Mitamura T; Umata T; Nakano F; Shishido Y; Toyoda T; Itai A; Kimura H; Mekada E
Structure-function analysis of the diphtheria toxin receptor toxin binding site by site-directed mutagenesis.
The Journal of biological chemistry 1997;272(43):27084-90.
1997: Tsuneoka M; Nakano F; Ohgusu H; Mekada E
c-myc activates RCC1 gene expression through E-box elements.
Oncogene 1997;14(19):2301-11.
1996: Nakagawa T; Higashiyama S; Mitamura T; Mekada E; Taniguchi N
Amino-terminal processing of cell surface heparin-binding epidermal growth factor-like growth factor up-regulates its juxtacrine but not its paracrine growth factor activity.
The Journal of biological chemistry 1996;271(48):30858-63.
1996: Mekada E; Shishido Y; Sharma K D
[Diphtheria toxin receptor complex]
Nippon saikingaku zasshi. Japanese journal of bacteriology 1996;51(3):853-62.
1996: Nakamura Y; Iwamoto R; Mekada E
Expression and distribution of CD9 in myelin of the central and peripheral nervous systems.
The American journal of pathology 1996;149(2):575-83.
1995: Shishido Y; Sharma K D; Higashiyama S; Klagsbrun M; Mekada E
Heparin-like molecules on the cell surface potentiate binding of diphtheria toxin to the diphtheria toxin receptor/membrane-anchored heparin-binding epidermal growth factor-like growth factor.
The Journal of biological chemistry 1995;270(49):29578-85.
1995: Goishi K; Higashiyama S; Klagsbrun M; Nakano N; Umata T; Ishikawa M; Mekada E; Taniguchi N
Phorbol ester induces the rapid processing of cell surface heparin-binding EGF-like growth factor: conversion from juxtacrine to paracrine growth factor activity.
Molecular biology of the cell 1995;6(8):967-80.
1995: Nakamura K; Iwamoto R; Mekada E
Membrane-anchored heparin-binding EGF-like growth factor (HB-EGF) and diphtheria toxin receptor-associated protein (DRAP27)/CD9 form a complex with integrin alpha 3 beta 1 at cell-cell contact sites.
The Journal of cell biology 1995;129(6):1691-705.
1995: Higashiyama S; Iwamoto R; Goishi K; Raab G; Taniguchi N; Klagsbrun M; Mekada E
The membrane protein CD9/DRAP 27 potentiates the juxtacrine growth factor activity of the membrane-anchored heparin-binding EGF-like growth factor.
The Journal of cell biology 1995;128(5):929-38.
1995: Mekada E
[CD9 and the family of four transmembrane domain proteins]
Seikagaku. The Journal of Japanese Biochemical Society 1995;67(3):224-8.
1995: Mitamura T; Higashiyama S; Taniguchi N; Klagsbrun M; Mekada E
Diphtheria toxin binds to the epidermal growth factor (EGF)-like domain of human heparin-binding EGF-like growth factor/diphtheria toxin receptor and inhibits specifically its mitogenic activity.
The Journal of biological chemistry 1995;270(3):1015-9.
1994: Iwamoto R; Higashiyama S; Mitamura T; Taniguchi N; Klagsbrun M; Mekada E
Heparin-binding EGF-like growth factor, which acts as the diphtheria toxin receptor, forms a complex with membrane protein DRAP27/CD9, which up-regulates functional receptors and diphtheria toxin sensitivity.
The EMBO journal 1994;13(10):2322-30.
1993: Tsuneoka M; Nakayama K; Hatsuzawa K; Komada M; Kitamura N; Mekada E
Evidence for involvement of furin in cleavage and activation of diphtheria toxin.
The Journal of biological chemistry 1993;268(35):26461-5.
1993: Koda Y; Kimura H; Mekada E
Analysis of Lewis fucosyltransferase genes from the human gastric mucosa of Lewis-positive and -negative individuals.
Blood 1993;82(9):2915-9.
1992: Mitamura T; Iwamoto R; Umata T; Yomo T; Urabe I; Tsuneoka M; Mekada E
The 27-kD diphtheria toxin receptor-associated protein (DRAP27) from vero cells is the monkey homologue of human CD9 antigen: expression of DRAP27 elevates the number of diphtheria toxin receptors on toxin-sensitive cells.
The Journal of cell biology 1992;118(6):1389-99.
1992: Tsuneoka M; Mekada E
Degradation of a nuclear-localized protein in mammalian COS cells, using Escherichia coli beta-galactosidase as a model protein.
The Journal of biological chemistry 1992;267(13):9107-11.
1991: Iwamoto R; Senoh H; Okada Y; Uchida T; Mekada E
An antibody that inhibits the binding of diphtheria toxin to cells revealed the association of a 27-kDa membrane protein with the diphtheria toxin receptor.
The Journal of biological chemistry 1991;266(30):20463-9.
1991: Mekada E; Senoh H; Iwamoto R; Okada Y; Uchida T
Purification of diphtheria toxin receptor from Vero cells.
The Journal of biological chemistry 1991;266(30):20457-62.
1990: Umata T; Moriyama Y; Futai M; Mekada E
The cytotoxic action of diphtheria toxin and its degradation in intact Vero cells are inhibited by bafilomycin A1, a specific inhibitor of vacuolar-type H(+)-ATPase.
The Journal of biological chemistry 1990;265(35):21940-5.
1988: Mekada E; Okada Y; Uchida T
Identification of diphtheria toxin receptor and a nonproteinous diphtheria toxin-binding molecule in Vero cell membrane.
The Journal of cell biology 1988;107(2):511-9.

Sign-in to see more

Sign-in free and Explore the Exciting World of BiomedExperts:

NetworkView

Eisuke Mekada

Research Profile (preview)

Chemicals & Drugs

Living Beings

Anatomy

Physiology

Genes & Molecular Sequences

Concepts & Ideas

Phenomena

Network (preview)

Publications

Sign in free and see...

Visualized networks:

GeoTargeted Searches:

Research Profiles:

Geonetwork of Eisuke Mekada (preview)

All Publications