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Daniel Meldrum

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Benjamin D Brewster; Joshua D Rouch; Meijing Wang; Daniel R Meldrum
Toll-like receptor 4 ablation improves stem cell survival after hypoxic injury.
Jeremy L Herrmann; Mariuxi C Manukyan; Aaron M Abarbanell; Benjamin D Brewster; Jeremy W Fiege; Jeffrey A Poynter; Yue Wang; Brent R Weil; Daniel R Meldrum
TGF-α equalizes age disparities in stem cell-mediated cardioprotection.
Todd J Wannemuehler; Benjamin D Brewster; Mariuxi C Manukyan; Jeffrey A Poynter; Joshua Rouch; Yue Wang; Daniel R Meldrum
Advances in mesenchymal stem cell research in sepsis.

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All Publications

2012: Benjamin D Brewster; Joshua D Rouch; Meijing Wang; Daniel R Meldrum
Toll-like receptor 4 ablation improves stem cell survival after hypoxic injury.
The Journal of surgical research 2012;177(2):330-3.
2012: Jeremy L Herrmann; Mariuxi C Manukyan; Aaron M Abarbanell; Benjamin D Brewster; Jeremy W Fiege; Jeffrey A Poynter; Yue Wang; Brent R Weil; Daniel R Meldrum
TGF-α equalizes age disparities in stem cell-mediated cardioprotection.
The Journal of surgical research 2012;176(2):386-94.
2012: Todd J Wannemuehler; Benjamin D Brewster; Mariuxi C Manukyan; Jeffrey A Poynter; Joshua Rouch; Yue Wang; Daniel R Meldrum
Advances in mesenchymal stem cell research in sepsis.
The Journal of surgical research 2012;173(1):113-26.
2012: Yong Luo; Mariuxi C Manukyan; Aaron M Abarbanell; Jeremy L Herrmann; Jeffrey A Poynter; Yue Wang; Brent R Weil; Daniel R Meldrum
Pretreating mesenchymal stem cells with interleukin-1β and transforming growth factor-β synergistically increases vascular endothelial growth factor production and improves mesenchymal stem cell-mediated myocardial protection after acute ischemia.
Surgery 2012;151(3):353-63.
2011: Jeremy L Herrmann; Mariuxi C Manukyan; Jeffrey A Poynter; Yue Wang; Brent R Weil; Aaron M Abarbanell; Daniel R Meldrum
Transforming growth factor-α enhances stem cell-mediated postischemic myocardial protection.
The Annals of thoracic surgery 2011;92(5):1719-25.
2011: Jeffrey A Poynter; Yue Wang; Brent R Weil; Aaron M Abarbanell; Benjamin D Brewster; Jeremy L Herrmann; Mariuxi C Manukyan; Daniel R Meldrum
Intracoronary mesenchymal stem cells promote postischemic myocardial functional recovery, decrease inflammation, and reduce apoptosis via a signal transducer and activator of transcription 3 mechanism.
Journal of the American College of Surgeons 2011;213(2):253-60.
2011: Brent R Weil; Mariuxi C Manukyan; Jeremy L Herrmann; Aaron M Abarbanell; Jeffrey A Poynter; Yue Wang; Daniel R Meldrum
The immunomodulatory properties of mesenchymal stem cells: implications for surgical disease.
The Journal of surgical research 2011;167(1):78-86.
2011: Jeremy L Herrmann; Aaron M Abarbanell; Brent R Weil; Mariuxi C Manukyan; Jeffrey A Poynter; Benjamin J Brewster; Yue Wang; Daniel R Meldrum
Optimizing stem cell function for the treatment of ischemic heart disease.
The Journal of surgical research 2011;166(1):138-45.
2010: Jeffrey A Poynter; Daniel J Beckman; Aaron M Abarbanell; Jeremy L Herrmann; Mariuxi C Manukyan; Brent R Weil; Karen Bumb; Daniel R Meldrum
Surgical treatment of atrial fibrillation: the time is now.
The Annals of thoracic surgery 2010;90(6):2079-86.
2010: Yue Wang; Aaron M Abarbanell; Jeremy L Herrmann; Brent R Weil; Jeffrey Poynter; Mariuxi C Manukyan; Paul R Crisostomo; Daniel R Meldrum
Toll-like receptor signaling pathways and the evidence linking toll-like receptor signaling to cardiac ischemia/reperfusion injury.
Shock (Augusta, Ga.) 2010;34(6):548-57.
2010: Jiangning Tan; Brent R Weil; Aaron M Abarbanell; Yue Wang; Jeremy L Herrmann; Megan L Dake; Daniel R Meldrum
Ablation of TNF-alpha receptors influences mesenchymal stem cell-mediated cardiac protection against ischemia.
Shock (Augusta, Ga.) 2010;34(3):236-42.
2010: Brent R Weil; Mariuxi C Manukyan; Jeremy L Herrmann; Yue Wang; Aaron M Abarbanell; Jeffrey A Poynter; Daniel R Meldrum
Mesenchymal stem cells attenuate myocardial functional depression and reduce systemic and myocardial inflammation during endotoxemia.
Surgery 2010;148(2):444-52.
2010: Brent R Weil; Mariuxi C Manukyan; Jeremy L Herrmann; Yue Wang; Aaron M Abarbanell; Jeffrey A Poynter; Daniel R Meldrum
Signaling via GPR30 protects the myocardium from ischemia/reperfusion injury.
Surgery 2010;148(2):436-43.
2010: Aaron M Abarbanell; Jeremy L Herrmann; Brent R Weil; Yue Wang; Jiangning Tan; Steven P Moberly; Jeremy W Fiege; Daniel R Meldrum
Animal models of myocardial and vascular injury.
The Journal of surgical research 2010;162(2):239-49.
2010: Aaron M Abarbanell; Yue Wang; Jeremy L Herrmann; Brent R Weil; Jeffrey A Poynter; Mariuxi C Manukyan; Daniel R Meldrum
Toll-like receptor 2 mediates mesenchymal stem cell-associated myocardial recovery and VEGF production following acute ischemia-reperfusion injury.
American journal of physiology. Heart and circulatory physiology 2010;298(5):H1529-36.
2010: Jeremy L Herrmann; Aaron M Abarbanell; Brent R Weil; Mariuxi C Manukyan; Jeffrey A Poynter; Yue Wang; Arthur C Coffey; Daniel R Meldrum
Gender dimorphisms in progenitor and stem cell function in cardiovascular disease.
Journal of cardiovascular translational research 2010;3(2):103-13.
2010: Yue Wang; Aaron M Abarbanell; Jeremy L Herrmann; Brent R Weil; Mariuxi C Manukyan; Jeffrey A Poynter; Daniel R Meldrum
TLR4 inhibits mesenchymal stem cell (MSC) STAT3 activation and thereby exerts deleterious effects on MSC-mediated cardioprotection.
PloS one 2010;5(12):e14206.
2009: Jeremy L Herrmann; Aaron M Abarbanell; Brent R Weil; Yue Wang; Meijing Wang; Jiangning Tan; Daniel R Meldrum
Cell-based therapy for ischemic heart disease: a clinical update.
The Annals of thoracic surgery 2009;88(5):1714-22.
2009: Yue Wang; Brent R Weil; Jeremy L Herrmann; Aaron M Abarbanell; Jiangning Tan; Troy A Markel; Megan L Kelly; Daniel R Meldrum
MEK, p38, and PI-3K mediate cross talk between EGFR and TNFR in enhancing hepatocyte growth factor production from human mesenchymal stem cells.
American journal of physiology. Cell physiology 2009;297(5):C1284-93.
2009: Meijing Wang; Jiangning Tan; Yue Wang; Kirstan K Meldrum; Charles A Dinarello; Daniel R Meldrum
IL-18 binding protein-expressing mesenchymal stem cells improve myocardial protection after ischemia or infarction.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(41):17499-504.
2009: Brent R Weil; Daniel R Meldrum
What's new in Shock, October 2009?
Shock (Augusta, Ga.) 2009;32(4):345-7.
2009: Yue Wang; Meijing Wang; Aaron M Abarbanell; Brent R Weil; Jeremy L Herrmann; Jiangning Tan; Nathan M Novotny; Arthur C Coffey; Daniel R Meldrum
MEK mediates the novel cross talk between TNFR2 and TGF-EGFR in enhancing vascular endothelial growth factor (VEGF) secretion from human mesenchymal stem cells.
Surgery 2009;146(2):198-205.
2009: Brent R Weil; Troy A Markel; Jeremy L Herrmann; Aaron M Abarbanell; Daniel R Meldrum
Mesenchymal stem cells enhance the viability and proliferation of human fetal intestinal epithelial cells following hypoxic injury via paracrine mechanisms.
Surgery 2009;146(2):190-7.
2009: Nicholas D Vornehm; Meijing Wang; Aaron Abarbanell; Jeremy Herrmann; Brent Weil; Jiangjing Tan; Yue Wang; Megan Kelly; Daniel R Meldrum
Acute postischemic treatment with estrogen receptor-alpha agonist or estrogen receptor-beta agonist improves myocardial recovery.
Surgery 2009;146(2):145-54.
2009: Meijing Wang; Yue Wang; Aaron Abarbanell; Jiangjing Tan; Brent Weil; Jeremy Herrmann; Daniel R Meldrum
Both endogenous and exogenous testosterone decrease myocardial STAT3 activation and SOCS3 expression after acute ischemia and reperfusion.
Surgery 2009;146(2):138-44.
2009: Jeremy L Herrmann; Troy A Markel; Aaron M Abarbanell; Brent R Weil; Meijing Wang; Yue Wang; Jiangning Tan; Daniel R Meldrum
Proinflammatory stem cell signaling in cardiac ischemia.
Antioxidants & redox signaling 2009;11(8):1883-96.
2009: Meijing Wang; Jiangning Tan; Arthur Coffey; John Fehrenbacher; Brent R Weil; Daniel R Meldrum
Signal transducer and activator of transcription 3-stimulated hypoxia inducible factor-1alpha mediates estrogen receptor-alpha-induced mesenchymal stem cell vascular endothelial growth factor production.
The Journal of thoracic and cardiovascular surgery 2009;138(1):163-71, 171.e1.
2009: Brent R Weil; Troy A Markel; Jeremy L Herrmann; Aaron M Abarbanell; Megan L Kelly; Daniel R Meldrum
Stem cells in sepsis.
Annals of surgery 2009;250(1):19-27.
2009: Troy A Markel; Paul R Crisostomo; Maiuxi C Manukyan; Dalia Al-Azzawi; Christine M Herring; Tim Lahm; Nathan M Novotny; Daniel R Meldrum
Are neonatal stem cells as effective as adult stem cells in providing ischemic protection?
The Journal of surgical research 2009;152(2):325-30.
2009: Nathan M Novotny; Tim Lahm; Troy A Markel; Paul R Crisostomo; Meijing Wang; Yue Wang; Jiangning Tan; Daniel R Meldrum
Angiopoietin-1 in the treatment of ischemia and sepsis.
Shock (Augusta, Ga.) 2009;31(4):335-41.
2009: Graham S Erwin; Paul R Crisostomo; Yue Wang; Meijing Wang; Troy A Markel; Mike Guzman; Ian C Sando; Rahul Sharma; Daniel R Meldrum
Estradiol-treated mesenchymal stem cells improve myocardial recovery after ischemia.
The Journal of surgical research 2009;152(2):319-24.
2009: Courtney N Zeller; Yue Wang; Troy A Markel; Brent Weil; Aaron Abarbanell; Jeremy L Herrmann; Megan L Kelly; Arthur Coffey; Daniel R Meldrum
Role of tumor necrosis factor receptor 1 in sex differences of stem cell mediated cardioprotection.
The Annals of thoracic surgery 2009;87(3):812-9.
2009: Nathan M Novotny; Tim Lahm; Troy A Markel; Paul R Crisostomo; Meijing Wang; Yue Wang; Rinki Ray; Jiangning Tan; Dalia Al-Azzawi; Daniel R Meldrum
beta-Blockers in sepsis: reexamining the evidence.
Shock (Augusta, Ga.) 2009;31(2):113-9.
2008: Matthew T Campbell; Pierre Dagher; Karen Hile; Hongji Zhang; Daniel R Meldrum; Richard C Rink; Kirstan K Meldrum
Tumor necrosis factor-alpha induces intrinsic apoptotic signaling during renal obstruction through truncated bid activation.
The Journal of urology 2008;180(6):2694-700.
2008: Michael J Guzman; Paul R Crisostomo; Meijing Wang; Troy A Markel; Yue Wang; Daniel R Meldrum
Vascular endothelial growth factor improves myocardial functional recovery following ischemia/reperfusion injury.
The Journal of surgical research 2008;150(2):286-92.
2008: Tim Lahm; Paul R Crisostomo; Troy A Markel; Meijing Wang; Yue Wang; Brent Weil; Daniel R Meldrum
Exogenous estrogen rapidly attenuates pulmonary artery vasoreactivity and acute hypoxic pulmonary vasoconstriction.
Shock (Augusta, Ga.) 2008;30(6):660-7.
2008: Troy A Markel; Paul R Crisostomo; Tim Lahm; Nathan M Novotny; Frederick J Rescorla; Joseph Tector; Daniel R Meldrum
Stem cells as a potential future treatment of pediatric intestinal disorders.
Journal of pediatric surgery 2008;43(11):1953-63.
2008: Paul R Crisostomo; Mithilesh K Das; Sandra Harston; Daniel R Meldrum
Left ventricular rupture: immediately before and after.
Journal of the American College of Surgeons 2008;207(5):784.
2008: Yue Wang; Paul R Crisostomo; Meijing Wang; Brent Weil; Aaron Abarbanell; Jeffrey Poynter; Mariuxi C Manukyan; Daniel R Meldrum
Nitric oxide suppresses the secretion of vascular endothelial growth factor and hepatocyte growth factor from human mesenchymal stem cells.
Shock (Augusta, Ga.) 2008;30(5):527-31.
2008: Ian C Sando; Yue Wang; Paul R Crisostomo; Troy A Markel; Rahul Sharma; Graham S Erwin; Mike J Guzman; Daniel R Meldrum; Meijing Wang
Females exhibit relative resistance to depressive effects of tumor necrosis factor-alpha on the myocardium.
The Journal of surgical research 2008;150(1):92-9.
2008: Meijing Wang; Paul R Crisostomo; Troy A Markel; Yue Wang; Daniel R Meldrum
Mechanisms of sex differences in TNFR2-mediated cardioprotection.
Circulation 2008;118(14 Suppl):S38-45.
2008: Nathan M Novotny; Rinki Ray; Troy A Markel; Paul R Crisostomo; Meijing Wang; Yue Wang; Daniel R Meldrum
Stem cell therapy in myocardial repair and remodeling.
Journal of the American College of Surgeons 2008;207(3):423-34.
2008: Meijing Wang; Paul R Crisostomo; Troy A Markel; Yue Wang; Keith D Lillemoe; Daniel R Meldrum
Estrogen receptor beta mediates acute myocardial protection following ischemia.
Surgery 2008;144(2):233-8.
2008: Nathan M Novotny; Troy A Markel; Paul R Crisostomo; Daniel R Meldrum
Differential IL-6 and VEGF secretion in adult and neonatal mesenchymal stem cells: role of NFkB.
Cytokine 2008;43(2):215-9.
2008: Meijing Wang; Troy A Markel; Daniel R Meldrum
Interleukin 18 in the heart.
Shock (Augusta, Ga.) 2008;30(1):3-10.
2008: Tim Lahm; Paul R Crisostomo; Troy A Markel; Meijing Wang; Brent R Weil; Nathan M Novotny; Daniel R Meldrum
The effects of estrogen on pulmonary artery vasoreactivity and hypoxic pulmonary vasoconstriction: potential new clinical implications for an old hormone.
Critical care medicine 2008;36(7):2174-83.
2008: Rinki Ray; Nathan M Novotny; Paul R Crisostomo; Tim Lahm; Aaron Abarbanell; Daniel R Meldrum
Sex steroids and stem cell function.
Molecular medicine (Cambridge, Mass.) 2008;14(7-8):493-501.
2008: Troy A Markel; George M Wairiuko; Tim Lahm; Paul R Crisostomo; Meijing Wang; Christine M Herring; Daniel R Meldrum
The right heart and its distinct mechanisms of development, function, and failure.
The Journal of surgical research 2008;146(2):304-13.
2008: Andrew M Terrell; Paul R Crisostomo; Troy A Markel; Meijing Wang; Aaron M Abarbanell; Jeremy L Herrmann; Daniel R Meldrum
Postischemic infusion of 17-beta-estradiol protects myocardial function and viability.
The Journal of surgical research 2008;146(2):218-24.
2008: Paul R Crisostomo; Troy A Markel; Yue Wang; Daniel R Meldrum
Surgically relevant aspects of stem cell paracrine effects.
Surgery 2008;143(5):577-81.
2008: Troy A Markel; Meijing Wang; Paul R Crisostomo; Maiuxi C Manukyan; Jeffrey A Poynter; Daniel R Meldrum
Neonatal stem cells exhibit specific characteristics in function, proliferation, and cellular signaling that distinguish them from their adult counterparts.
American journal of physiology. Regulatory, integrative and comparative physiology 2008;294(5):R1491-7.
2008: Rinki Ray; Christine M Herring; Troy A Markel; Paul R Crisostomo; Meijing Wang; Brent Weil; Tim Lahm; Daniel R Meldrum
Deleterious effects of endogenous and exogenous testosterone on mesenchymal stem cell VEGF production.
American journal of physiology. Regulatory, integrative and comparative physiology 2008;294(5):R1498-503.
2008: Ketan M Patel; Tim Lahm; Paul R Crisostomo; Christine M Herring; Troy A Markel; Meijing Wang; Daniel R Meldrum
The effects of endogenous sex hormones and acute hypoxia on vasoconstriction in isolated rat pulmonary artery rings.
The Journal of surgical research 2008;146(1):121-6.
2008: Paul R Crisostomo; Yue Wang; Troy A Markel; Meijing Wang; Tim Lahm; Daniel R Meldrum
Human mesenchymal stem cells stimulated by TNF-alpha, LPS, or hypoxia produce growth factors by an NF kappa B- but not JNK-dependent mechanism.
American journal of physiology. Cell physiology 2008;294(3):C675-82.
2008: Ben M Tsai; Tim Lahm; Eric D Morrell; Paul R Crisostomo; Jeffrey Poynter; Meijing Wang; Daniel R Meldrum
Ethyl pyruvate inhibits hypoxic pulmonary vasoconstriction and attenuates pulmonary artery cytokine expression.
The Journal of surgical research 2008;145(1):130-4.
2008: Peter D Metcalfe; Jeffrey A Leslie; Matthew T Campbell; Daniel R Meldrum; Karen L Hile; Kirstan K Meldrum
Testosterone exacerbates obstructive renal injury by stimulating TNF-alpha production and increasing proapoptotic and profibrotic signaling.
American journal of physiology. Endocrinology and metabolism 2008;294(2):E435-43.
2007: Ketan M Patel; Paul R Crisostomo; Tim Lahm; Troy A Markel; Christine M Herring; Meijing Wang; Kirstan K Meldrum; Keith D Lillemoe; Daniel R Meldrum
Mesenchymal stem cells attenuate hypoxic pulmonary vasoconstriction by a paracrine mechanism.
The Journal of surgical research 2007;143(2):281-5.
2007: Troy A Markel; Paul R Crisostomo; Meijing Wang; Jeremy L Herrmann; Aaron M Abarbanell; Daniel R Meldrum
Right ventricular TNF resistance during endotoxemia: the differential effects on ventricular function.
American journal of physiology. Regulatory, integrative and comparative physiology 2007;293(5):R1893-7.
2007: Meijing Wang; Wenjun Zhang; Paul R Crisostomo; Troy A Markel; Kirstan K Meldrum; Xin-Yuan Fu; Daniel R Meldrum
Endothelial STAT3 plays a critical role in generalized myocardial proinflammatory and proapoptotic signaling.
American journal of physiology. Heart and circulatory physiology 2007;293(4):H2101-8.
2007: Troy A Markel; Paul R Crisostomo; Meijing Wang; Christine M Herring; Daniel R Meldrum
Activation of individual tumor necrosis factor receptors differentially affects stem cell growth factor and cytokine production.
American journal of physiology. Gastrointestinal and liver physiology 2007;293(4):G657-62.
2007: Paul R Crisostomo; Meijing Wang; Troy A Markel; Tim Lahm; Aaron M Abarbanell; Jeremy L Herrmann; Daniel R Meldrum
Stem cell mechanisms and paracrine effects: potential in cardiac surgery.
Shock (Augusta, Ga.) 2007;28(4):375-83.
2007: Un Hui Nam; Meijing Wang; Paul R Crisostomo; Troy A Markel; Tim Lahm; Kirstan K Meldrum; Keith D Lillemoe; Daniel R Meldrum
The effect of chronic exogenous androgen on myocardial function following acute ischemia-reperfusion in hosts with different baseline levels of sex steroids.
The Journal of surgical research 2007;142(1):113-8.
2007: Tim Lahm; Ketan M Patel; Paul R Crisostomo; Troy A Markel; Meijing Wang; Christine M Herring; Daniel R Meldrum
Endogenous estrogen attenuates pulmonary artery vasoreactivity and acute hypoxic pulmonary vasoconstriction: the effects of sex and menstrual cycle.
American journal of physiology. Endocrinology and metabolism 2007;293(3):E865-71.
2007: Meijing Wang; Wenjun Zhang; Paul R Crisostomo; Troy A Markel; Kirstan K Meldrum; Xin-Yuan Fu; Daniel R Meldrum
Sex differences in endothelial STAT3 mediate sex differences in myocardial inflammation.
American journal of physiology. Endocrinology and metabolism 2007;293(3):E872-7.
2007: Paul R Crisostomo; Troy A Markel; Meijing Wang; Tim Lahm; Keith D Lillemoe; Daniel R Meldrum
In the adult mesenchymal stem cell population, source gender is a biologically relevant aspect of protective power.
Surgery 2007;142(2):215-21.
2007: George M Wairiuko; Paul R Crisostomo; Meijing Wang; Eric D Morrell; Kirstan K Meldrum; Keith D Lillemoe; Daniel R Meldrum
Stem cells improve right ventricular functional recovery after acute pressure overload and ischemia reperfusion injury.
The Journal of surgical research 2007;141(2):241-6.
2007: Tim Lahm; Paul R Crisostomo; Troy A Markel; Meijing Wang; Keith D Lillemoe; Daniel R Meldrum
The critical role of vascular endothelial growth factor in pulmonary vascular remodeling after lung injury.
Shock (Augusta, Ga.) 2007;28(1):4-14.
2007: Meijing Wang; Wenjun Zhang; Paul R Crisostomo; Troy A Markel; Kirstan K Meldrum; Xin-Yuan Fu; Daniel R Meldrum
STAT3 mediates bone marrow mesenchymal stem cell VEGF production.
Journal of molecular and cellular cardiology 2007;42(6):1009-15.
2007: Tim Lahm; Daniel R Meldrum
Point:Counterpoint "Release of an endothelium-derived vasoconstrictor and RhoA/Rho kinase-mediated calcium sensitization of smooth muscle cell contraction are/are not the main effectors for full and sustained hypoxic pulmonary vasoconstriction".
Journal of applied physiology (Bethesda, Md. : 1985) 2007;102(5):2077-8; discussion 2080.
2007: Troy A Markel; Paul R Crisostomo; Meijing Wang; Christine M Herring; Tim Lahm; Kirstan K Meldrum; Keith D Lillemoe; Frederick J Rescorla; Daniel R Meldrum
Iron chelation acutely stimulates fetal human intestinal cell production of IL-6 and VEGF while decreasing HGF: the roles of p38, ERK, and JNK MAPK signaling.
American journal of physiology. Gastrointestinal and liver physiology 2007;292(4):G958-63.
2007: Kirstan K Meldrum; Rosalia Misseri; P Metcalfe; C A Dinarello; Karen Hile; Daniel R Meldrum
TNF-alpha neutralization ameliorates obstruction-induced renal fibrosis and dysfunction.
American journal of physiology. Regulatory, integrative and comparative physiology 2007;292(4):R1456-64.
2007: Meijing Wang; Troy A Markel; Paul R Crisostomo; Christine M Herring; Kirstan K Meldrum; Keith D Lillemoe; Daniel R Meldrum
Deficiency of TNFR1 protects myocardium through SOCS3 and IL-6 but not p38 MAPK or IL-1beta.
American journal of physiology. Heart and circulatory physiology 2007;292(4):H1694-9.
2007: Troy A Markel; Paul R Crisostomo; Meijing Wang; Christine M Herring; Kirstan K Meldrum; Keith D Lillemoe; Daniel R Meldrum
The struggle for iron: gastrointestinal microbes modulate the host immune response during infection.
Journal of leukocyte biology 2007;81(2):393-400.
2007: Ben M Tsai; Ketan Patel; Meijing Wang; Eric D Morrell; Paul R Crisostomo; Daniel R Meldrum
Selective protein kinase C inhibition attenuates pulmonary artery cytokine expression without affecting hypoxic pulmonary vasoconstriction.
Shock (Augusta, Ga.) 2007;27(1):36-9.
2007: Paul R Crisostomo; Meijing Wang; Christine M Herring; Troy A Markel; Kirstan K Meldrum; Keith D Lillemoe; Daniel R Meldrum
Gender differences in injury induced mesenchymal stem cell apoptosis and VEGF, TNF, IL-6 expression: role of the 55 kDa TNF receptor (TNFR1).
Journal of molecular and cellular cardiology 2007;42(1):142-9.
2006: Paul R Crisostomo; Meijing Wang; George M Wairiuko; Eric D Morrell; Andrew M Terrell; Preethi Seshadri; Un Hui Nam; Daniel R Meldrum
High passage number of stem cells adversely affects stem cell activation and myocardial protection.
Shock (Augusta, Ga.) 2006;26(6):575-80.
2006: Paul R Crisostomo; Meijing Wang; Christine M Herring; Eric D Morrell; Preethi Seshadri; Kirstan K Meldrum; Daniel R Meldrum
Sex dimorphisms in activated mesenchymal stem cell function.
Shock (Augusta, Ga.) 2006;26(6):571-4.
2006: Norbert F Voelkel; Robert A Quaife; Leslie A Leinwand; Robyn J Barst; Michael D McGoon; Daniel R Meldrum; Jocelyn Dupuis; Carlin S Long; Lewis J Rubin; Frank W Smart; Yuichiro J Suzuki; Mark Gladwin; Elizabeth M Denholm; Dorothy B Gail
Right ventricular function and failure: report of a National Heart, Lung, and Blood Institute working group on cellular and molecular mechanisms of right heart failure.
Circulation 2006;114(17):1883-91.
2006: Meijing Wang; Paul R Crisostomo; Christine M Herring; Kirstan K Meldrum; Daniel R Meldrum
Human progenitor cells from bone marrow or adipose tissue produce VEGF, HGF, and IGF-I in response to TNF by a p38 MAPK-dependent mechanism.
American journal of physiology. Regulatory, integrative and comparative physiology 2006;291(4):R880-4.
2006: Andrew M Terrell; Paul R Crisostomo; George M Wairiuko; Meijing Wang; Eric D Morrell; Daniel R Meldrum
Jak/STAT/SOCS signaling circuits and associated cytokine-mediated inflammation and hypertrophy in the heart.
Shock (Augusta, Ga.) 2006;26(3):226-34.
2006: Paul R Crisostomo; Meijing Wang; George M Wairiuko; Andrew M Terrell; Daniel R Meldrum
Postconditioning in females depends on injury severity.
The Journal of surgical research 2006;134(2):342-7.
2006: Eric D Morrell; Ben M Tsai; Meijing Wang; Paul R Crisostomo; Daniel R Meldrum
p38 mitogen-activated protein kinase mediates the sustained phase of hypoxic pulmonary vasoconstriction and plays a role in phase I vasodilation.
The Journal of surgical research 2006;134(2):335-41.
2006: Meijing Wang; Ben M Tsai; Paul R Crisostomo; Daniel R Meldrum
Tumor necrosis factor receptor 1 signaling resistance in the female myocardium during ischemia.
Circulation 2006;114(1 Suppl):I282-9.
2006: Eric D Morrell; Ben M Tsai; Paul R Crisostomo; Meijing Wang; Troy A Markel; Keith D Lillemoe; Daniel R Meldrum
Therapeutic concepts for hypoxic pulmonary vasoconstriction involving ion regulation and the smooth muscle contractile apparatus.
Journal of molecular and cellular cardiology 2006;40(6):751-60.
2006: Meijing Wang; Paul R Crisostomo; George M Wairiuko; Daniel R Meldrum
Estrogen receptor-alpha mediates acute myocardial protection in females.
American journal of physiology. Heart and circulatory physiology 2006;290(6):H2204-9.
2006: Meijing Wang; Ben M Tsai; Paul R Crisostomo; Daniel R Meldrum
Pretreatment with adult progenitor cells improves recovery and decreases native myocardial proinflammatory signaling after ischemia.
Shock (Augusta, Ga.) 2006;25(5):454-9.
2006: Paul R Crisostomo; George M Wairiuko; Meijing Wang; Ben M Tsai; Eric D Morrell; Daniel R Meldrum
Preconditioning versus postconditioning: mechanisms and therapeutic potentials.
Journal of the American College of Surgeons 2006;202(5):797-812.
2006: Paul R Crisostomo; Meijing Wang; George M Wairiuko; Eric D Morrell; Daniel R Meldrum
Brief exposure to exogenous testosterone increases death signaling and adversely affects myocardial function after ischemia.
American journal of physiology. Regulatory, integrative and comparative physiology 2006;290(5):R1168-74.
2006: Troy A Markel; Paul R Crisostomo; George M Wairiuko; Jeffrey M Pitcher; Ben M Tsai; Daniel R Meldrum
Cytokines in necrotizing enterocolitis.
Shock (Augusta, Ga.) 2006;25(4):329-37.
2006: Kirstan K Meldrum; Peter Metcalfe; Jeffrey A Leslie; Rosalia Misseri; Karen Hile; Daniel R Meldrum
TNF-alpha neutralization decreases nuclear factor-kappaB activation and apoptosis during renal obstruction.
The Journal of surgical research 2006;131(2):182-8.
2006: Eric D Morrell; Ben M Tsai; Paul R Crisostomo; Zane T Hammoud; Daniel R Meldrum
Experimental therapies for hypoxia-induced pulmonary hypertension during acute lung injury.
Shock (Augusta, Ga.) 2006;25(3):214-26.
2006: Daniel R Meldrum
Estrogen increases protective proteins following trauma and hemorrhage.
American journal of physiology. Regulatory, integrative and comparative physiology 2006;290(3):R809-11.
2006: Nicholas T Nelson; Adam J Mahomed; Jeffrey M Pitcher; Ben M Tsai; Meijing Wang; Yousuf Mahomed; John W Brown; Paul R Crisostomo; Daniel R Meldrum
Does endogenous testosterone mediate the lower preconditioning threshold in males?
The Journal of surgical research 2006;131(1):86-90.
2006: Ben M Tsai; Meijing Wang; Jeffrey M Pitcher; Ajay Kher; Daniel R Meldrum
Disparate IL-1beta and iNOS gene expression in the aorta and pulmonary artery after endotoxemia.
Surgical infections 2006;7(1):21-7.
2006: Jeffrey M Pitcher; Meijing Wang; Ben M Tsai; Ajay Kher; Nicholas T Nelson; Daniel R Meldrum
Endogenous estrogen mediates a higher threshold for endotoxin-induced myocardial protection in females.
American journal of physiology. Regulatory, integrative and comparative physiology 2006;290(1):R27-33.
2005: Meijing Wang; Ben M Tsai; Mark W Turrentine; Yousuf Mahomed; John W Brown; Daniel R Meldrum
p38 mitogen activated protein kinase mediates both death signaling and functional depression in the heart.
The Annals of thoracic surgery 2005;80(6):2235-41.
2005: Jeffrey M Pitcher; Meijing Wang; Ben M Tsai; Ajay Kher; Mark W Turrentine; John W Brown; Daniel R Meldrum
Preconditioning: gender effects.
The Journal of surgical research 2005;129(2):202-20.
2005: Ben M Tsai; Meijing Wang; Jeffrey M Pitcher; Ajay Kher; Paul R Crisostomo; Daniel R Meldrum
Zaprinast attenuates hypoxic pulmonary artery injury and causes less aortic relaxation than milrinone.
Shock (Augusta, Ga.) 2005;24(5):417-20.
2005: Ryan D Nagy; Ben M Tsai; Meijing Wang; Troy A Markel; John W Brown; Daniel R Meldrum
Stem cell transplantation as a therapeutic approach to organ failure.
The Journal of surgical research 2005;129(1):152-60.
2005: Ajay Kher; Kirstan K Meldrum; Karen Hile; Meijing Wang; Ben M Tsai; Mark W Turrentine; John W Brown; Daniel R Meldrum
Aprotinin improves kidney function and decreases tubular cell apoptosis and proapoptotic signaling after renal ischemia-reperfusion.
The Journal of thoracic and cardiovascular surgery 2005;130(3):662-9.
2005: Ajay Kher; Kirstan K Meldrum; Meijing Wang; Ben M Tsai; Jeffrey M Pitcher; Daniel R Meldrum
Cellular and molecular mechanisms of sex differences in renal ischemia-reperfusion injury.
Cardiovascular research 2005;67(4):594-603.
2005: Jeffrey M Pitcher; Ben M Tsai; Meijing Wang; Ajay Kher; John W Brown; Daniel R Meldrum
Sexual dimorphism in myocardial tumor necrosis factor-alpha and cardiac function during endotoxin tolerance.
Surgery 2005;138(2):223-8.
2005: Ben M Tsai; Meijing Wang; Jeffrey M Pitcher; Ajay Kher; John W Brown; Daniel R Meldrum
Endothelium-dependent pulmonary artery vasorelaxation is dysfunctional in males but not females after acute lung injury.
Surgery 2005;138(1):78-84.
2005: Jeffrey M Pitcher; Ryan D Nagy; Ben M Tsai; Meijing Wang; Ajay Kher; Daniel R Meldrum
Is the preconditioning threshold different in females?
The Journal of surgical research 2005;125(2):168-72.
2005: Rosalia Misseri; Daniel R Meldrum; C A Dinarello; P Dagher; Karen Hile; Richard C Rink; Kirstan K Meldrum
TNF-alpha mediates obstruction-induced renal tubular cell apoptosis and proapoptotic signaling.
American journal of physiology. Renal physiology 2005;288(2):F406-11.
2005: Meijing Wang; Lauren Baker; Ben M Tsai; Kirstan K Meldrum; Daniel R Meldrum
Sex differences in the myocardial inflammatory response to ischemia-reperfusion injury.
American journal of physiology. Endocrinology and metabolism 2005;288(2):E321-6.
2005: Daniel R Meldrum; Meijing Wang; Ben M Tsai; Ajay Kher; Jeffrey M Pitcher; John W Brown; Kirstan K Meldrum
Intracellular signaling mechanisms of sex hormones in acute myocardial inflammation and injury.
Frontiers in bioscience : a journal and virtual library 2005;10():1835-67.
2005: Ajay Kher; Meijing Wang; Ben M Tsai; Jeffrey M Pitcher; Evan S Greenbaum; Ryan D Nagy; Ketan M Patel; George M Wairiuko; Troy A Markel; Daniel R Meldrum
Sex differences in the myocardial inflammatory response to acute injury.
Shock (Augusta, Ga.) 2005;23(1):1-10.
2005: Meijing Wang; Ben M Tsai; Ajay Kher; Lauren B Baker; George M Wairiuko; Daniel R Meldrum
Role of endogenous testosterone in myocardial proinflammatory and proapoptotic signaling after acute ischemia-reperfusion.
American journal of physiology. Heart and circulatory physiology 2005;288(1):H221-6.
2004: Ben M Tsai; Meijing Wang; Jeffrey M Pitcher; Kirstan K Meldrum; Daniel R Meldrum
Hypoxic pulmonary vasoconstriction and pulmonary artery tissue cytokine expression are mediated by protein kinase C.
American journal of physiology. Lung cellular and molecular physiology 2004;287(6):L1215-9.
2004: Rosalia Misseri; Daniel R Meldrum; Pierre Dagher; Karen Hile; Richard C Rink; Kirstan K Meldrum
Unilateral ureteral obstruction induces renal tubular cell production of tumor necrosis factor-alpha independent of inflammatory cell infiltration.
The Journal of urology 2004;172(4 Pt 2):1595-9; discussion 1599.
2004: Ben M Tsai; Meijing Wang; Matthias Clauss; Peichuan Sun; Daniel R Meldrum
Endothelial monocyte-activating polypeptide II causes NOS-dependent pulmonary artery vasodilation: a novel effect for a proinflammatory cytokine.
American journal of physiology. Regulatory, integrative and comparative physiology 2004;287(4):R767-71.
2004: Meijng Wang; Xianzhong Meng; Ben M Tsai; Ju-Feng Wang; Mark W Turrentine; John W Brown; Daniel R Meldrum
Preconditioning up-regulates the soluble TNF receptor I response to endotoxin.
The Journal of surgical research 2004;121(1):20-4.
2004: Ben M Tsai; Meijing Wang; Mark W Turrentine; Yousuf Mahomed; John W Brown; Daniel R Meldrum
Hypoxic pulmonary vasoconstriction in cardiothoracic surgery: basic mechanisms to potential therapies.
The Annals of thoracic surgery 2004;78(1):360-8.
2004: Daniel R Meldrum
Basic science: why do we do it?
The Journal of surgical research 2004;119(2):160-1.
2004: Rosalia Misseri; Richard C Rink; Daniel R Meldrum; Kirstan K Meldrum
Inflammatory mediators and growth factors in obstructive renal injury.
The Journal of surgical research 2004;119(2):149-59.
2004: Ben M Tsai; Meijing Wang; Keith March; Mark W Turrentine; John W Brown; Daniel R Meldrum
Preconditioning: evolution of basic mechanisms to potential therapeutic strategies.
Shock (Augusta, Ga.) 2004;21(3):195-209.
2004: Meijing Wang; Rajakumar Sankula; Ben M Tsai; Kirstan K Meldrum; Mark W Turrentine; Keith March; John W Brown; Charles A Dinarello; Daniel R Meldrum
P38 MAPK mediates myocardial proinflammatory cytokine production and endotoxin-induced contractile suppression.
Shock (Augusta, Ga.) 2004;21(2):170-4.
2003: Lauren Baker; Kirstan K Meldrum; Meijing Wang; Rajakumar Sankula; Ram Vanam; Azad Raiesdana; Ben M Tsai; Karen Hile; John W Brown; Daniel R Meldrum
The role of estrogen in cardiovascular disease.
The Journal of surgical research 2003;115(2):325-44.
2003: Daniel R Meldrum; David A Partrick; Joseph C Cleveland; Robert Shenkar; Kirstan K Meldrum; Azad Raiesdana; Alfred Ayala; John W Brown; Alden H Harken
On-pump coronary artery bypass surgery activates human myocardial NF-kappaB and increases TNF-alpha in the heart.
The Journal of surgical research 2003;112(2):175-9.
2003: Kirstan K Meldrum; Arthur L Burnett; Xianzhong Meng; Rosalia Misseri; Matthew B K Shaw; John P Gearhart; Daniel R Meldrum
Liposomal delivery of heat shock protein 72 into renal tubular cells blocks nuclear factor-kappaB activation, tumor necrosis factor-alpha production, and subsequent ischemia-induced apoptosis.
Circulation research 2003;92(3):293-9.
2002: Kirstan K Meldrum; Karen Hile; Daniel R Meldrum; J A Crone; John P Gearhart; Arthur L Burnett
Simulated ischemia induces renal tubular cell apoptosis through a nuclear factor-kappaB dependent mechanism.
The Journal of urology 2002;168(1):248-52.
2002: Kirstan K Meldrum; Daniel R Meldrum; Xianzhong Meng; Lihua Ao; Alden H Harken
TNF-alpha-dependent bilateral renal injury is induced by unilateral renal ischemia-reperfusion.
American journal of physiology. Heart and circulatory physiology 2002;282(2):H540-6.
2001: Christopher D Raeburn; Ernest E Moore; Walter L Biffl; Jeffrey L Johnson; Daniel R Meldrum; Patrick J Offner; Reginald J Franciose; Jon M Burch
The abdominal compartment syndrome is a morbid complication of postinjury damage control surgery.
American journal of surgery 2001;182(6):542-6.
2001: Kirstan K Meldrum; Daniel R Meldrum; Karen Hile; Arthur L Burnett; Alden H Harken
A novel model of ischemia in renal tubular cells which closely parallels in vivo injury.
The Journal of surgical research 2001;99(2):288-93.
2001: Kirstan K Meldrum; Daniel R Meldrum; Karen Hile; Elizabeth B Yerkes; A Ayala; M P Cain; R C Rink; A J Casale; M A Kaefer
p38 MAPK mediates renal tubular cell TNF-alpha production and TNF-alpha-dependent apoptosis during simulated ischemia.
American journal of physiology. Cell physiology 2001;281(2):C563-70.
2001: Kirstan K Meldrum; Daniel R Meldrum; Sena F Sezen; Julie K Crone; Arthur L Burnett
Heat shock prevents simulated ischemia-induced apoptosis in renal tubular cells via a PKC-dependent mechanism.
American journal of physiology. Regulatory, integrative and comparative physiology 2001;281(1):R359-64.
2001: KK Donnahoo; Xianzhong Meng; Lihua Ao; A Ayala; Brian D Shames; M P Cain; Alden H Harken; Daniel R Meldrum
Differential cellular immunolocalization of renal tumour necrosis factor-alpha production during ischaemia versus endotoxaemia.
Immunology 2001;102(1):53-8.
2000: Ben Eiseman; Ernest E Moore; Daniel R Meldrum; Christopher D Raeburn
Feasibility of damage control surgery in the management of military combat casualties.
Archives of surgery (Chicago, Ill. : 1960) 2000;135(11):1323-7.
2000: KK Donnahoo; Daniel R Meldrum; R Shenkar; C S Chung; Edward Abraham; Alden H Harken
Early renal ischemia, with or without reperfusion, activates NFkappaB and increases TNF-alpha bioactivity in the kidney.
The Journal of urology 2000;163(4):1328-32.
2000: David A Partrick; Ernest E Moore; Patrick J Offner; Daniel R Meldrum; Douglas Y Tamura; Jeffrey L Johnson; Christopher C Silliman
Maximal human neutrophil priming for superoxide production and elastase release requires p38 mitogen-activated protein kinase activation.
Archives of surgery (Chicago, Ill. : 1960) 2000;135(2):219-25.
1999: BS Cain; Daniel R Meldrum; Joseph C Cleveland; Xianzhong Meng; Anirban Banerjee; Alden H Harken
Clinical L-type Ca(2+) channel blockade prevents ischemic preconditioning of human myocardium.
Journal of molecular and cellular cardiology 1999;31(12):2191-7.
1999: Brett C Sheridan; Charles A Dinarello; Daniel R Meldrum; David A Fullerton; Craig H Selzman; Robert C McIntyre
Interleukin-11 attenuates pulmonary inflammation and vasomotor dysfunction in endotoxin-induced lung injury.
The American journal of physiology 1999;277(5 Pt 1):L861-7.
1999: BS Cain; Daniel R Meldrum; Xianzhong Meng; Edward J Pulido; Brian D Shames; Craig H Selzman; Anirban Banerjee; Alden H Harken
Exogenous calcium preconditions myocardium from patients taking oral sulfonylurea agents.
The Journal of surgical research 1999;86(2):171-6.
1999: KK Donnahoo; Xianzhong Meng; A Ayala; M P Cain; Alden H Harken; Daniel R Meldrum
Early kidney TNF-alpha expression mediates neutrophil infiltration and injury after renal ischemia-reperfusion.
The American journal of physiology 1999;277(3 Pt 2):R922-9.
1999: David A Partrick; Ernest E Moore; D A Fullerton; Carlton C Barnett; Daniel R Meldrum; Christopher C Silliman
Cardiopulmonary bypass renders patients at risk for multiple organ failure via early neutrophil priming and late neutrophil disability.
The Journal of surgical research 1999;86(1):42-9.
1999: Daniel R Meldrum; Xianzhong Meng; Brian D Shames; Benjamin J Pomerantz; KK Donnahoo; Anirban Banerjee; Alden H Harken
Liposomal delivery of heat-shock protein 72 into the heart prevents endotoxin-induced myocardial contractile dysfunction.
Surgery 1999;126(2):135-41.
1999: Daniel R Meldrum; KK Donnahoo
Role of TNF in mediating renal insufficiency following cardiac surgery: evidence of a postbypass cardiorenal syndrome.
The Journal of surgical research 1999;85(2):185-99.
1999: BS Cain; Daniel R Meldrum; Charles A Dinarello; Xianzhong Meng; KS Joo; Anirban Banerjee; Alden H Harken
Tumor necrosis factor-alpha and interleukin-1beta synergistically depress human myocardial function.
Critical care medicine 1999;27(7):1309-18.
1999: Daniel R Meldrum; David A Partrick; Brett C Sheridan; Ernest E Moore; Alden H Harken
Kinetics of interleukin-11 release after cardiopulmonary bypass.
The Journal of thoracic and cardiovascular surgery 1999;118(1):193-5.
1999: Daniel R Meldrum; BS Cain; Xianzhong Meng; Joseph C Cleveland; Brian D Shames; KK Donnahoo; Anirban Banerjee; Alden H Harken
Calcium preconditioning, but not ischemic preconditioning, bypasses the adenosine triphosphate-dependent potassium (KATP) channel.
The Journal of surgical research 1999;85(1):77-82.
1999: KK Donnahoo; Brian D Shames; Alden H Harken; Daniel R Meldrum
Review article: the role of tumor necrosis factor in renal ischemia-reperfusion injury.
The Journal of urology 1999;162(1):196-203.
1999: Xianzhong Meng; Anirban Banerjee; Lihua Ao; Daniel R Meldrum; BS Cain; Brian D Shames; Alden H Harken
Inhibition of myocardial TNF-alpha production by heat shock. A potential mechanism of stress-induced cardioprotection against postischemic dysfunction.
Annals of the New York Academy of Sciences 1999;874():69-82.
1999: BS Cain; Alden H Harken; Daniel R Meldrum
Therapeutic strategies to reduce TNF-alpha mediated cardiac contractile depression following ischemia and reperfusion.
Journal of molecular and cellular cardiology 1999;31(5):931-47.
1999: Xianzhong Meng; Brian D Shames; Edward J Pulido; Daniel R Meldrum; Lihua Ao; KS Joo; Alden H Harken; Anirban Banerjee
Adrenergic induction of bimodal myocardial protection: signal transduction and cardiac gene reprogramming.
The American journal of physiology 1999;276(5 Pt 2):R1525-33.
1999: Brian D Shames; Craig H Selzman; Edward J Pulido; Xianzhong Meng; Daniel R Meldrum; Robert C McIntyre; Alden H Harken; Anirban Banerjee
LPS-Induced NF-kappaB activation and TNF-alpha release in human monocytes are protein tyrosine kinase dependent and protein kinase C independent.
The Journal of surgical research 1999;83(1):69-74.
1999: BS Cain; Daniel R Meldrum; Xianzhong Meng; C A Dinarello; Brian D Shames; Anirban Banerjee; Alden H Harken
p38 MAPK inhibition decreases TNF-alpha production and enhances postischemic human myocardial function.
The Journal of surgical research 1999;83(1):7-12.
1999: BS Cain; Daniel R Meldrum; Alden H Harken
Protein kinase C in normal and pathologic myocardial states.
The Journal of surgical research 1999;81(2):249-59.
1999: Brett C Sheridan; Robert C McIntyre; Daniel R Meldrum; David A Fullerton
L-arginine attenuates endothelial dysfunction in endotoxin-induced lung injury.
Surgery 1999;125(1):33-40.
1998: Craig H Selzman; Daniel R Meldrum; BS Cain; Xianzhong Meng; Brian D Shames; Lihua Ao; Alden H Harken
Interleukin-10 inhibits postinjury tumor necrosis factor-mediated human vascular smooth muscle proliferation.
The Journal of surgical research 1998;80(2):352-6.
1998: Brian D Shames; Craig H Selzman; Daniel R Meldrum; Edward J Pulido; HA Barton; Xianzhong Meng; Alden H Harken; Robert C McIntyre
Interleukin-10 stabilizes inhibitory kappaB-alpha in human monocytes.
Shock (Augusta, Ga.) 1998;10(6):389-94.
1998: Daniel R Meldrum; Charles A Dinarello; Brian D Shames; Joseph C Cleveland; BS Cain; Anirban Banerjee; Xianzhong Meng; Alden H Harken
Ischemic preconditioning decreases postischemic myocardial tumor necrosis factor-alpha production. Potential ultimate effector mechanism of preconditioning.
Circulation 1998;98(19 Suppl):II214-8; discussion II218-9.
1998: Robert C McIntyre; Edward J Pulido; Brett C Sheridan; Daniel R Meldrum; Denis D Bensard; David A Fullerton
Endotoxin differentially impairs receptor-mediated relaxation in rat isolated pulmonary and thoracic aortic vessels.
The Journal of trauma 1998;45(5):862-7.
1998: Daniel R Meldrum; Xianzhong Meng; C A Dinarello; A Ayala; BS Cain; Brian D Shames; Lihua Ao; Anirban Banerjee; Alden H Harken
Human myocardial tissue TNFalpha expression following acute global ischemia in vivo.
Journal of molecular and cellular cardiology 1998;30(9):1683-9.
1998: Brian D Shames; Daniel R Meldrum; Craig H Selzman; Edward J Pulido; BS Cain; Anirban Banerjee; Alden H Harken; Xianzhong Meng
Increased levels of myocardial IkappaB-alpha protein promote tolerance to endotoxin.
The American journal of physiology 1998;275(3 Pt 2):H1084-91.
1998: T F Rehring; Joseph Shapiro; BS Cain; Daniel R Meldrum; Joseph C Cleveland; Alden H Harken; Anirban Banerjee
Mechanisms of pH preservation during global ischemia in preconditioned rat heart: roles for PKC and NHE.
The American journal of physiology 1998;275(3 Pt 2):H805-13.
1998: Daniel R Meldrum; Brian D Shames; Xianzhong Meng; David A Fullerton; Robert C McIntyre; Frederick L Grover; Alden H Harken
Nitric oxide downregulates lung macrophage inflammatory cytokine production.
The Annals of thoracic surgery 1998;66(2):313-7.
1998: BS Cain; Daniel R Meldrum; KS Joo; J F Wang; Xianzhong Meng; Joseph C Cleveland; Anirban Banerjee; Alden H Harken
Human SERCA2a levels correlate inversely with age in senescent human myocardium.
Journal of the American College of Cardiology 1998;32(2):458-67.
1998: Daniel R Meldrum; C A Dinarello; Joseph C Cleveland; BS Cain; Brian D Shames; Xianzhong Meng; Alden H Harken
Hydrogen peroxide induces tumor necrosis factor alpha-mediated cardiac injury by a P38 mitogen-activated protein kinase-dependent mechanism.
Surgery 1998;124(2):291-6; discussion 297.
1998: Xianzhong Meng; Lihua Ao; Daniel R Meldrum; BS Cain; Brian D Shames; Craig H Selzman; Anirban Banerjee; Alden H Harken
TNF-alpha and myocardial depression in endotoxemic rats: temporal discordance of an obligatory relationship.
The American journal of physiology 1998;275(2 Pt 2):R502-8.
1998: Brian D Shames; Craig H Selzman; X Meng; Daniel R Meldrum; B S Cain; Alden H Harken
Genes don't count.
Archives of surgery (Chicago, Ill. : 1960) 1998;133(6):667-9.
1998: BS Cain; Daniel R Meldrum; Xianzhong Meng; Edward J Pulido; Anirban Banerjee; Alden H Harken
Therapeutic antidysrhythmic and functional protection in human atria.
The Journal of surgical research 1998;76(2):143-8.
1998: BS Cain; Daniel R Meldrum; C A Dinarello; Xianzhong Meng; Anirban Banerjee; Alden H Harken
Adenosine reduces cardiac TNF-alpha production and human myocardial injury following ischemia-reperfusion.
The Journal of surgical research 1998;76(2):117-23.
1998: Daniel R Meldrum; Xianzhong Meng; Brett C Sheridan; Robert C McIntyre; Alden H Harken; Anirban Banerjee
Tissue-specific protein kinase C isoforms differentially mediate macrophage TNFalpha and IL-1beta production.
Shock (Augusta, Ga.) 1998;9(4):256-60.
1998: BS Cain; Daniel R Meldrum; Xianzhong Meng; Brian D Shames; Anirban Banerjee; Alden H Harken
Calcium preconditioning in human myocardium.
The Annals of thoracic surgery 1998;65(4):1065-70.
1998: Daniel R Meldrum
Tumor necrosis factor in the heart.
The American journal of physiology 1998;274(3 Pt 2):R577-95.
1998: Brett C Sheridan; Robert C McIntyre; Daniel R Meldrum; David A Fullerton
L-arginine prevents lung neutrophil accumulation and preserves pulmonary endothelial function after endotoxin.
The American journal of physiology 1998;274(3 Pt 1):L337-42.
1998: B S Cain; Daniel R Meldrum; Alden H Harken; Robert C McIntyre
The physiologic basis for anticytokine clinical trials in the treatment of sepsis.
Journal of the American College of Surgeons 1998;186(3):337-50.
1998: Daniel R Meldrum; Joseph C Cleveland; BS Cain; Xianzhong Meng; Alden H Harken
Increased myocardial tumor necrosis factor-alpha in a crystalloid-perfused model of cardiac ischemia-reperfusion injury.
The Annals of thoracic surgery 1998;65(2):439-43.
1997: Daniel R Meldrum; BS Cain; Joseph C Cleveland; Xianzhong Meng; A Ayala; A Banerjee; Alden H Harken
Adenosine decreases post-ischaemic cardiac TNF-alpha production: anti-inflammatory implications for preconditioning and transplantation.
Immunology 1997;92(4):472-7.
1997: Daniel R Meldrum; Robert C McIntyre; Brett C Sheridan; Joseph C Cleveland; David A Fullerton; Alden H Harken
L-arginine decreases alveolar macrophage proinflammatory monokine production during acute lung injury by a nitric oxide synthase-dependent mechanism.
The Journal of trauma 1997;43(6):888-93.
1997: Daniel R Meldrum; Frederick A Moore; Ernest E Moore; Reginald J Franciose; Angela Sauaia; Jon M Burch
Prospective characterization and selective management of the abdominal compartment syndrome.
American journal of surgery 1997;174(6):667-72; discussion 672-3.
1997: Daniel R Meldrum
Mechanisms of cardiac preconditioning: ten years after the discovery of ischemic preconditioning.
The Journal of surgical research 1997;73(1):1-13.
1997: Brett C Sheridan; Robert C McIntyre; Daniel R Meldrum; David A Fullerton
KATP channels contribute to beta- and adenosine receptor-mediated pulmonary vasorelaxation.
The American journal of physiology 1997;273(5 Pt 1):L950-6.
1997: Xianzhong Meng; Lihua Ao; James M Brown; Daniel R Meldrum; Brett C Sheridan; BS Cain; Anirban Banerjee; Alden H Harken
LPS induces late cardiac functional protection against ischemia independent of cardiac and circulating TNF-alpha.
The American journal of physiology 1997;273(4 Pt 2):H1894-902.
1997: Daniel R Meldrum; Robert Shenkar; Brett C Sheridan; BS Cain; Edward Abraham; Alden H Harken
Hemorrhage activates myocardial NFkappaB and increases TNF-alpha in the heart.
Journal of molecular and cellular cardiology 1997;29(10):2849-54.
1997: Brett C Sheridan; Robert C McIntyre; Daniel R Meldrum; Xianzhong Meng; David A Fullerton
Endotoxin stuns cGMP-mediated pulmonary vasorelaxation.
Shock (Augusta, Ga.) 1997;8(3):207-12.
1997: BS Cain; Daniel R Meldrum; Craig H Selzman; Joseph C Cleveland; Xianzhong Meng; Brett C Sheridan; Anirban Banerjee; Alden H Harken
Surgical implications of vascular endothelial physiology.
Surgery 1997;122(3):516-26.
1997: RT Rowland; Xianzhong Meng; Joseph C Cleveland; Daniel R Meldrum; Alden H Harken; James M Brown
Cardioadaptation induced by cyclic ischemic preconditioning is mediated by translational regulation of de novo protein synthesis.
The Journal of surgical research 1997;71(2):155-60.
1997: Brett C Sheridan; Robert C McIntyre; Daniel R Meldrum; David A Fullerton
Pentoxifylline treatment attenuates pulmonary vasomotor dysfunction in acute lung injury.
The Journal of surgical research 1997;71(2):150-4.
1997: Brett C Sheridan; Robert C McIntyre; Daniel R Meldrum; David A Fullerton
Phosphodiesterase inhibition overcomes pulmonary vasomotor dysfunction in acute lung injury.
The Journal of surgical research 1997;71(2):145-9.
1997: Joseph C Cleveland; Daniel R Meldrum; RT Rowland; BS Cain; Xianzhong Meng; Fabia Gamboni-Robertson; Anirban Banerjee; Alden H Harken
Ischemic preconditioning of human myocardium: protein kinase C mediates a permissive role for alpha 1-adrenoceptors.
The American journal of physiology 1997;273(2 Pt 2):H902-8.
1997: Daniel R Meldrum; Joseph C Cleveland; RT Rowland; Anirban Banerjee; Alden H Harken; Xianzhong Meng
Early and delayed preconditioning: differential mechanisms and additive protection.
The American journal of physiology 1997;273(2 Pt 2):H725-33.
1997: BS Cain; Daniel R Meldrum; KS Joo; R J Davis; Alden H Harken
Diastolic hibernation masquerading as constrictive pericarditis.
Journal of cardiac surgery 1997;12(4):235-7.
1997: Joseph C Cleveland; Daniel R Meldrum; BS Cain; Anirban Banerjee; Alden H Harken
Oral sulfonylurea hypoglycemic agents prevent ischemic preconditioning in human myocardium. Two paradoxes revisited.
Circulation 1997;96(1):29-32.
1997: RT Rowland; Xianzhong Meng; Joseph C Cleveland; Daniel R Meldrum; Alden H Harken; James M Brown
LPS-induced delayed myocardial adaptation enhances acute preconditioning to optimize postischemic cardiac function.
The American journal of physiology 1997;272(6 Pt 2):H2708-15.
1997: Daniel R Meldrum; Joseph C Cleveland; Brett C Sheridan; RT Rowland; Craig H Selzman; Anirban Banerjee; Alden H Harken
Alpha-adrenergic activation of myocardial NF kappa B during hemorrhage.
The Journal of surgical research 1997;69(2):268-76.
1997: Daniel R Meldrum; Joseph C Cleveland; Xianzhong Meng; Brett C Sheridan; F Gamboni; BS Cain; Alden H Harken; Anirban Banerjee
Protein kinase C isoform diversity in preconditioning.
The Journal of surgical research 1997;69(1):183-7.
1997: Brett C Sheridan; Robert C McIntyre; Ernest E Moore; Daniel R Meldrum; J Agrafojo; David A Fullerton
Neutrophils mediate pulmonary vasomotor dysfunction in endotoxin-induced acute lung injury.
The Journal of trauma 1997;42(3):391-6; discussion 396-7.
1997: Daniel R Meldrum; Joseph C Cleveland; Xianzhong Meng; Brett C Sheridan; Anirban Banerjee; Alden H Harken
Hemorrhage induces acute cardioadaptation to ischemia-reperfusion by an alpha1-adrenoceptor-mediated, protein synthesis-independent mechanism.
The American journal of physiology 1997;272(2 Pt 2):R718-25.
1997: Joseph C Cleveland; Daniel R Meldrum; RT Rowland; Anirban Banerjee; Alden H Harken
Adenosine preconditioning of human myocardium is dependent upon the ATP-sensitive K+ channel.
Journal of molecular and cellular cardiology 1997;29(1):175-82.
1997: Joseph C Cleveland; Daniel R Meldrum; RT Rowland; Anirban Banerjee; Alden H Harken
Preconditioning and hypothermic cardioplegia protect human heart equally against ischemia.
The Annals of thoracic surgery 1997;63(1):147-52.
1996: Joseph C Cleveland; M M Wollmering; Daniel R Meldrum; RT Rowland; T F Rehring; Brett C Sheridan; Alden H Harken; Anirban Banerjee
Ischemic preconditioning in human and rat ventricle.
The American journal of physiology 1996;271(5 Pt 2):H1786-94.
1996: Brett C Sheridan; Robert C McIntyre; J Agrafojo; Daniel R Meldrum; Xianzhong Meng; David A Fullerton
Neutrophil depletion attenuates endotoxin-induced dysfunction of cGMP-mediated pulmonary vasorelaxation.
The American journal of physiology 1996;271(5 Pt 1):L820-8.
1996: Daniel R Meldrum; Brett C Sheridan; Joseph C Cleveland; David A Fullerton; Anirban Banerjee; Alden H Harken
Neutrophils are required for endotoxin-induced myocardial cross-tolerance to ischemia-reperfusion injury.
Archives of surgery (Chicago, Ill. : 1960) 1996;131(11):1203-8.
1996: Daniel R Meldrum; Joseph C Cleveland; Brett C Sheridan; RT Rowland; Anirban Banerjee; Alden H Harken
Differential effects of adenosine preconditioning on the postischemic rat myocardium.
The Journal of surgical research 1996;65(2):159-64.
1996: Daniel R Meldrum; Joseph C Cleveland; Max B Mitchell; RT Rowland; Anirban Banerjee; Alden H Harken
Constructive priming of myocardium against ischemia-reperfusion injury.
Shock (Augusta, Ga.) 1996;6(4):238-42.
1996: Anirban Banerjee; F Gamboni-Robertson; Max B Mitchell; T F Rehring; K Butler; J Cleveland; Daniel R Meldrum; Joseph Shapiro; X Z Meng
Stress-induced cardioadaptation reveals a code linking hormone receptors and spatial redistribution of PKC isoforms.
Annals of the New York Academy of Sciences 1996;793():226-39.
1996: Daniel R Meldrum; Joseph C Cleveland; Max B Mitchell; Brett C Sheridan; F Gamboni-Robertson; Alden H Harken; Anirban Banerjee
Protein kinase C mediates Ca2(+)-induced cardioadaptation to ischemia-reperfusion injury.
The American journal of physiology 1996;271(3 Pt 2):R718-26.
1996: Daniel R Meldrum; Joseph C Cleveland; Brett C Sheridan; RT Rowland; Anirban Banerjee; Alden H Harken
Cardiac preconditioning with calcium: clinically accessible myocardial protection.
The Journal of thoracic and cardiovascular surgery 1996;112(3):778-86.
1996: Joseph C Cleveland; Daniel R Meldrum; RT Rowland; Brett C Sheridan; Anirban Banerjee; Alden H Harken
The obligate role of protein kinase C in mediating clinically accessible cardiac preconditioning.
Surgery 1996;120(2):345-52; discussion 352-3.
1996: Brett C Sheridan; Robert C McIntyre; Daniel R Meldrum; Joseph C Cleveland; J Agrafojo; J H Eisenach; David A Fullerton
Vinblastine attenuates endotoxin-induced impairment of CGMP-mediated pulmonary vasorelaxation.
Shock (Augusta, Ga.) 1996;6(1):35-8.
1996: Daniel R Meldrum; Joseph C Cleveland; RT Rowland; Anirban Banerjee; Alden H Harken
Calcium-induced inotropy is in part mediated by protein kinase C.
The Journal of surgical research 1996;63(2):400-5.
1996: Brett C Sheridan; Robert C McIntyre; Daniel R Meldrum; Joseph C Cleveland; J Agrafojo; Anirban Banerjee; Alden H Harken; David A Fullerton
Microtubules regulate pulmonary vascular smooth muscle contraction.
The Journal of surgical research 1996;62(2):284-7.
1996: Daniel R Meldrum; Joseph C Cleveland; Brett C Sheridan; RT Rowland; Anirban Banerjee; Alden H Harken
Cardiac surgical implications of calcium dyshomeostasis in the heart.
The Annals of thoracic surgery 1996;61(4):1273-80.
1996: Brett C Sheridan; Robert C McIntyre; Daniel R Meldrum; Joseph C Cleveland; J Agrafojo; J H Eisenach; Alden H Harken; David A Fullerton
Antibody-mediated neutrophil depletion preserves pulmonary vasomotor function.
The Journal of surgical research 1996;62(1):74-8.
1996: Daniel R Meldrum; Alden H Harken
On "preconditioning of skeletal muscle: application to dynamic cardiomyoplasty" by C. David Ianuzzo, et al.
Journal of cardiac surgery 1996;11(2):109-10.
1996: Joseph C Cleveland; Daniel R Meldrum; RT Rowland; Anirban Banerjee; Alden H Harken
Optimal myocardial preservation: cooling, cardioplegia, and conditioning.
The Annals of thoracic surgery 1996;61(2):760-8.
1993: Daniel R Meldrum; Max B Mitchell; Anirban Banerjee; Alden H Harken
Cardiac preconditioning. Induction of endogenous tolerance to ischemia-reperfusion injury.
Archives of surgery (Chicago, Ill. : 1960) 1993;128(11):1208-11.