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Cornelis Melief

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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TOP 3
Kenter Gemma G; Welters Marij J P; Valentijn A Rob P M; Lowik Margriet J G; Berends-van der Meer Dorien M A; Vloon Annelies P G; Essahsah Farah; Fathers Lorraine M; Offringa Rienk; Drijfhout Jan Wouter; Wafelman Amon R; Oostendorp Jaap; Fleuren Gert Jan; van der Burg Sjoerd H; Melief Cornelis J M
Vaccination against HPV-16 oncoproteins for vulvar intraepithelial neoplasia.
Karim Rezaul; Jordanova Ekaterina S; Piersma Sytse J; Kenter Gemma G; Chen Lieping; Boer Judith M; Melief Cornelis J M; van der Burg Sjoerd H
Tumor-expressed B7-H1 and B7-DC in relation to PD-1+ T-cell infiltration and survival of patients with cervical carcinoma.
Buschow Sonja I; Nolte-'t Hoen Esther N M; van Niel Guillaume; Pols Maaike S; ten Broeke Toine; Lauwen Marjolein; Ossendorp Ferry; Melief Cornelis J M; Raposo Graça; Wubbolts Richard; Wauben Marca H M; Stoorvogel Willem
MHC II in dendritic cells is targeted to lysosomes or T cell-induced exosomes via distinct multivesicular body pathways.

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All Publications

2009: Kenter Gemma G; Welters Marij J P; Valentijn A Rob P M; Lowik Margriet J G; Berends-van der Meer Dorien M A; Vloon Annelies P G; Essahsah Farah; Fathers Lorraine M; Offringa Rienk; Drijfhout Jan Wouter; Wafelman Amon R; Oostendorp Jaap; Fleuren Gert Jan; van der Burg Sjoerd H; Melief Cornelis J M
Vaccination against HPV-16 oncoproteins for vulvar intraepithelial neoplasia.
The New England journal of medicine 2009;361(19):1838-47.
2009: Karim Rezaul; Jordanova Ekaterina S; Piersma Sytse J; Kenter Gemma G; Chen Lieping; Boer Judith M; Melief Cornelis J M; van der Burg Sjoerd H
Tumor-expressed B7-H1 and B7-DC in relation to PD-1+ T-cell infiltration and survival of patients with cervical carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(20):6341-7.
2009: Buschow Sonja I; Nolte-'t Hoen Esther N M; van Niel Guillaume; Pols Maaike S; ten Broeke Toine; Lauwen Marjolein; Ossendorp Ferry; Melief Cornelis J M; Raposo Graça; Wubbolts Richard; Wauben Marca H M; Stoorvogel Willem
MHC II in dendritic cells is targeted to lysosomes or T cell-induced exosomes via distinct multivesicular body pathways.
Traffic (Copenhagen, Denmark) 2009;10(10):1528-42.
2009: van den Boorn Jasper G; Konijnenberg Debby; Dellemijn Trees A M; van der Veen J P Wietze; Bos Jan D; Melief Cornelis J M; Vyth-Dreese Florry A; Luiten Rosalie M
Autoimmune destruction of skin melanocytes by perilesional T cells from vitiligo patients.
The Journal of investigative dermatology 2009;129(9):2220-32.
2009: Fu Nathalie; Khan Selina; Quinten Edwin; de Graaf Natascha; Pemberton Alex J; Rivett A Jennifer; Melief Cornelis J M; Ossendorp Ferry
Effective CD8(+) T cell priming and tumor protection by enterotoxin B subunit-conjugated peptides targeted to dendritic cells.
Vaccine 2009;27(38):5252-8.
2009: Han Wanda G H; Schuurhuis Danita H; Fu Nathalie; Camps Marcel; van Duivenvoorde Leonie M; Louis-Plence Pascale; Franken Kees L M C; Huizinga Tom W J; Melief Cornelis J M; Toes René E M; Ossendorp Ferry
DC-induced CD8(+) T-cell response is inhibited by MHC class II-dependent DX5(+)CD4(+) Treg.
European journal of immunology 2009;39(7):1765-73.
2009: Berghuis Dagmar; de Hooge Alfons S K; Santos Susy J; Horst Danielle; Wiertz Emmanuel J; van Eggermond Marja C; van den Elsen Peter J; Taminiau Antonie H M; Ottaviano Laura; Schaefer Karl-Ludwig; Dirksen Uta; Hooijberg Erik; Mulder Arend; Melief Cornelis J M; Egeler R Maarten; Schilham Marco W; Jordanova Ekaterina S; Hogendoorn Pancras C W; Lankester Arjan C
Reduced human leukocyte antigen expression in advanced-stage Ewing sarcoma: implications for immune recognition.
The Journal of pathology 2009;218(2):222-31.
2009: Weterings Jimmy J; Khan Selina; van der Heden van Noort Gerbrand J; Melief Cornelis J M; Overkleeft Herman S; van der Burg Sjoerd H; Ossendorp Ferry; van der Marel Gijsbert A; Filippov Dmitri V
2-Azidoalkoxy-7-hydro-8-oxoadenine derivatives as TLR7 agonists inducing dendritic cell maturation.
Bioorganic & medicinal chemistry letters 2009;19(8):2249-51.
2009: Khan Selina; Weterings Jimmy J; Britten Cedrik M; de Jong Ana R; Graafland Dirk; Melief Cornelis J M; van der Burg Sjoerd H; van der Marel Gijs; Overkleeft Hermen S; Filippov Dmitri V; Ossendorp Ferry
Chirality of TLR-2 ligand Pam3CysSK4 in fully synthetic peptide conjugates critically influences the induction of specific CD8+ T-cells.
Molecular immunology 2009;46(6):1084-91.
2009: Speetjens Frank M; Kuppen Peter J K; Welters Marij J P; Essahsah Farah; Voet van den Brink Anne Marie E G; Lantrua M Graziella Kallenberg; Valentijn A Rob P M; Oostendorp Jaap; Fathers Lorraine M; Nijman Hans W; Drijfhout Jan W; van de Velde Cornelis J H; Melief Cornelis J M; van der Burg Sjoerd H
Induction of p53-specific immunity by a p53 synthetic long peptide vaccine in patients treated for metastatic colorectal cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(3):1086-95.
2008: Bos Rinke; van Duikeren Suzanne; Morreau Hans; Franken Kees; Schumacher Ton N M; Haanen John B; van der Burg Sjoerd H; Melief Cornelis J M; Offringa Rienk
Balancing between antitumor efficacy and autoimmune pathology in T-cell-mediated targeting of carcinoembryonic antigen.
Cancer research 2008;68(20):8446-55.
2008: Melief Cornelis J M
Cancer immunotherapy by dendritic cells.
Immunity 2008;29(3):372-83.
2008: Verhoeven Dirk H J; de Hooge Alfons S K; Mooiman Esther C K; Santos Susy Justo; ten Dam Monique M; Gelderblom Hans; Melief Cornelis J M; Hogendoorn Pancras C W; Egeler R Maarten; van Tol Maarten J D; Schilham Marco W; Lankester Arjan C
NK cells recognize and lyse Ewing sarcoma cells through NKG2D and DNAM-1 receptor dependent pathways.
Molecular immunology 2008;45(15):3917-25.
2008: Speetjens Frank M; Lauwen Marjolein M; Franken Kees L; Janssen-van Rhijn Connie M; van Duikeren Suzanne; Bres Sandra A; van de Velde Cornelis J H; Melief Cornelis J M; Kuppen Peter J K; van der Burg Sjoerd H; Morreau Hans; Offringa Rienk
Prediction of the immunogenic potential of frameshift-mutated antigens in microsatellite instable cancer.
International journal of cancer. Journal international du cancer 2008;123(4):838-45.
2008: van den Hende Muriel; van Poelgeest Mariëtte I E; van der Hulst Jeanette M; de Jong Joan; Drijfhout Jan W; Fleuren Gert Jan; Valentijn A Rob P M; Wafelman Amon R; Slappendel Gijs M; Melief Cornelis J M; Offringa Rienk; van der Burg Sjoerd H; Kenter Gemma G
Skin reactions to human papillomavirus (HPV) 16 specific antigens intradermally injected in healthy subjects and patients with cervical neoplasia.
International journal of cancer. Journal international du cancer 2008;123(1):146-52.
2008: Melief Cornelis J M; van der Burg Sjoerd H
Immunotherapy of established (pre)malignant disease by synthetic long peptide vaccines.
Nature reviews. Cancer 2008;8(5):351-60.
2008: Bijker Martijn S; van den Eeden Susan J F; Franken Kees L; Melief Cornelis J M; van der Burg Sjoerd H; Offringa Rienk
Superior induction of anti-tumor CTL immunity by extended peptide vaccines involves prolonged, DC-focused antigen presentation.
European journal of immunology 2008;38(4):1033-42.
2008: Lauwen Marjolein M; Zwaveling Sander; de Quartel Linda; Ferreira Mota S Carmela; Grashorn Janine A C; Melief Cornelis J M; van der Burg Sjoerd H; Offringa Rienk
Self-tolerance does not restrict the CD4+ T-helper response against the p53 tumor antigen.
Cancer research 2008;68(3):893-900.
2008: Piersma Sytse J; Welters Marij J P; van der Hulst Jeanette M; Kloth Judith N; Kwappenberg Kitty M C; Trimbos Baptist J; Melief Cornelis J M; Hellebrekers Bart W; Fleuren Gert Jan; Kenter Gemma G; Offringa Rienk; van der Burg Sjoerd H
Human papilloma virus specific T cells infiltrating cervical cancer and draining lymph nodes show remarkably frequent use of HLA-DQ and -DP as a restriction element.
International journal of cancer. Journal international du cancer 2008;122(3):486-94.
2008: Welters Marij J P; Kenter Gemma G; Piersma Sytse J; Vloon Annelies P G; Löwik Margriet J G; Berends-van der Meer Dorien M A; Drijfhout Jan W; Valentijn A Rob P M; Wafelman Amon R; Oostendorp Jaap; Fleuren Gert Jan; Offringa Rienk; Melief Cornelis J M; van der Burg Sjoerd H
Induction of tumor-specific CD4+ and CD8+ T-cell immunity in cervical cancer patients by a human papillomavirus type 16 E6 and E7 long peptides vaccine.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(1):178-87.
2008: Kenter Gemma G; Welters Marij J P; Valentijn A Rob P M; Lowik Margriet J G; Berends-van der Meer Dorien M A; Vloon Annelies P G; Drijfhout Jan W; Wafelman Amon R; Oostendorp Jaap; Fleuren Gert Jan; Offringa Rienk; van der Burg Sjoerd H; Melief Cornelis J M
Phase I immunotherapeutic trial with long peptides spanning the E6 and E7 sequences of high-risk human papillomavirus 16 in end-stage cervical cancer patients shows low toxicity and robust immunogenicity.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(1):169-77.
2007: Melief Cornelis J M
Cancer: immune pact with the enemy.
Nature 2007;450(7171):803-4.
2007: Bos Rinke; van Duikeren Suzanne; van Hall Thorbald; Lauwen Marjolein M; Parrington Mark; Berinstein Neil L; McNeil Bryan; Melief Cornelis J M; Verbeek J Sjef; van der Burg Sjoerd H; Offringa Rienk
Characterization of antigen-specific immune responses induced by canarypox virus vaccines.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(9):6115-22.
2007: Bijker Martijn S; van den Eeden Susan J F; Franken Kees L; Melief Cornelis J M; Offringa Rienk; van der Burg Sjoerd H
CD8+ CTL priming by exact peptide epitopes in incomplete Freund's adjuvant induces a vanishing CTL response, whereas long peptides induce sustained CTL reactivity.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(8):5033-40.
2007: Kessler J H; Melief C J M
Identification of T-cell epitopes for cancer immunotherapy.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2007;21(9):1859-74.
2007: Bijker Martijn S; Melief Cornelis J M; Offringa Rienk; van der Burg Sjoerd H
Design and development of synthetic peptide vaccines: past, present and future.
Expert review of vaccines 2007;6(4):591-603.
2007: van der Burg Sjoerd H; Piersma Sytse J; de Jong Annemieke; van der Hulst Jeanette M; Kwappenberg Kitty M C; van den Hende Muriel; Welters Marij J P; Van Rood Jon J; Fleuren Gert Jan; Melief Cornelis J M; Kenter Gemma G; Offringa Rienk
Association of cervical cancer with the presence of CD4+ regulatory T cells specific for human papillomavirus antigens.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(29):12087-92.
2007: Khan Selina; Bijker Martijn S; Weterings Jimmy J; Tanke Hans J; Adema Gosse J; van Hall Thorbald; Drijfhout Jan W; Melief Cornelis J M; Overkleeft Hermen S; van der Marel Gijsbert A; Filippov Dmitri V; van der Burg Sjoerd H; Ossendorp Ferry
Distinct uptake mechanisms but similar intracellular processing of two different toll-like receptor ligand-peptide conjugates in dendritic cells.
The Journal of biological chemistry 2007;282(29):21145-59.
2007: Loeser Stefanie; Loser Karin; Bijker Martijn S; Rangachari Manu; van der Burg Sjoerd H; Wada Teiji; Beissert Stefan; Melief Cornelis J M; Penninger Josef M
Spontaneous tumor rejection by cbl-b-deficient CD8+ T cells.
The Journal of experimental medicine 2007;204(4):879-91.
2007: Welters Marij J P; Bijker Martijn S; van den Eeden Susan J F; Franken Kees L M C; Melief Cornelis J M; Offringa Rienk; van der Burg Sjoerd H
Multiple CD4 and CD8 T-cell activation parameters predict vaccine efficacy in vivo mediated by individual DC-activating agonists.
Vaccine 2007;25(8):1379-89.
2007: Piersma Sytse J; Jordanova Ekaterina S; van Poelgeest Mariëtte I E; Kwappenberg Kitty M C; van der Hulst Jeanette M; Drijfhout Jan W; Melief Cornelis J M; Kenter Gemma G; Fleuren Gert Jan; Offringa Rienk; van der Burg Sjoerd H
High number of intraepithelial CD8+ tumor-infiltrating lymphocytes is associated with the absence of lymph node metastases in patients with large early-stage cervical cancer.
Cancer research 2007;67(1):354-61.
2007: de Hooge Alfons S K; Berghuis Dagmar; Santos Susy Justo; Mooiman Esther; Romeo Salvatore; Kummer J Alain; Egeler R Maarten; van Tol Maarten J D; Melief Cornelis J M; Hogendoorn Pancras C W; Lankester Arjan C
Expression of cellular FLICE inhibitory protein, caspase-8, and protease inhibitor-9 in Ewing sarcoma and implications for susceptibility to cytotoxic pathways.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(1):206-14.
2006: van der Burg Sjoerd H; Bijker Martijn S; Welters Marij J P; Offringa R; Melief Cornelis J M
Improved peptide vaccine strategies, creating synthetic artificial infections to maximize immune efficacy.
Advanced drug delivery reviews 2006;58(8):916-30.
2006: Kessler J H; Bres-Vloemans S A; van Veelen P A; de Ru A; Huijbers I J G; Camps M; Mulder A; Offringa R; Drijfhout J W; Leeksma O C; Ossendorp F; Melief C J M
BCR-ABL fusion regions as a source of multiple leukemia-specific CD8+ T-cell epitopes.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2006;20(10):1738-50.
2006: Smyth Lucy J C; Elkord Eyad; Taher Taher E I; Jiang Hui-Rong; Burt Deborah J; Clayton Alison; van Veelen Peter A; de Ru Arnoud; Ossendorp Ferry; Melief Cornelis J M; Drijfhout Jan W; Dermime Said; Hawkins Robert E; Stern Peter L
CD8 T-cell recognition of human 5T4 oncofetal antigen.
International journal of cancer. Journal international du cancer 2006;119(7):1638-47.
2006: Veltrop-Duits Louise A; Heemskerk Bianca; Sombroek Claudia C; van Vreeswijk Tamara; Gubbels Sophie; Toes René E M; Melief Cornelis J M; Franken Kees L M C; Havenga Menzo; van Tol Maarten J D; Schilham Marco W
Human CD4+ T cells stimulated by conserved adenovirus 5 hexon peptides recognize cells infected with different species of human adenovirus.
European journal of immunology 2006;36(9):2410-23.
2006: Boonman Zita F H M; Schurmans Lucas R H M; van Rooijen Nico; Melief Cornelis J M; Toes René E M; Jager Martine J
Macrophages are vital in spontaneous intraocular tumor eradication.
Investigative ophthalmology & visual science 2006;47(7):2959-65.
2006: Weterings Jimmy J; Khan Selina; van der Heden Gerbrand J; Drijfhout Jan W; Melief Cornelis J M; Overkleeft Herman S; van der Burg Sjoerd H; Ossendorp Ferry; van der Marel Gijsbert A; Filippov Dmitri V
Synthesis of 2-alkoxy-8-hydroxyadenylpeptides: towards synthetic epitope-based vaccines.
Bioorganic & medicinal chemistry letters 2006;16(12):3258-61.
2006: Griffioen Marieke; Kessler Jan H; Borghi Martina; van Soest Ronald A; van der Minne Caroline E; Nouta Jan; van der Burg Sjoerd H; Medema Jan Paul; Schrier Peter I; Falkenburg J H Frederik; Osanto Susanne; Melief Cornelis J M
Detection and functional analysis of CD8+ T cells specific for PRAME: a target for T-cell therapy.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(10):3130-6.
2006: Schuurhuis Danita H; van Montfoort Nadine; Ioan-Facsinay Andreea; Jiawan Reshma; Camps Marcel; Nouta Jan; Melief Cornelis J M; Verbeek J Sjef; Ossendorp Ferry
Immune complex-loaded dendritic cells are superior to soluble immune complexes as antitumor vaccine.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(8):4573-80.
2006: van Hall Thorbald; Wolpert Elisabeth Z; van Veelen Peter; Laban Sandra; van der Veer Michael; Roseboom Marjet; Bres Sandra; Grufman Per; de Ru Arnoud; Meiring Hugo; de Jong Ad; Franken Kees; Teixeira Antoinette; Valentijn Rob; Drijfhout Jan Wouter; Koning Frits; Camps Marcel; Ossendorp Ferry; Kärre Klas; Ljunggren Hans-Gustaf; Melief Cornelis J M; Offringa Rienk
Selective cytotoxic T-lymphocyte targeting of tumor immune escape variants.
Nature medicine 2006;12(4):417-24.
2006: Welters Marij J P; van der Logt Pauline; van den Eeden Susan J F; Kwappenberg Kitty M C; Drijfhout Jan Wouter; Fleuren Gert Jan; Kenter Gemma G; Melief Cornelis J M; van der Burg Sjoerd H; Offringa Rienk
Detection of human papillomavirus type 18 E6 and E7-specific CD4+ T-helper 1 immunity in relation to health versus disease.
International journal of cancer. Journal international du cancer 2006;118(4):950-6.
2006: van Poelgeest Mariëtte I E; Nijhuis Esther R; Kwappenberg Kitty M C; Hamming Ineke E; Wouter Drijfhout Jan; Fleuren Gert Jan; van der Zee Ate G J; Melief Cornelis J M; Kenter Gemma G; Nijman Hans W; Offringa Rienk; van der Burg Sjoerd H
Distinct regulation and impact of type 1 T-cell immunity against HPV16 L1, E2 and E6 antigens during HPV16-induced cervical infection and neoplasia.
International journal of cancer. Journal international du cancer 2006;118(3):675-83.
2006: Cavallo Federica; Offringa Rienk; van der Burg Sjoerd H; Forni Guido; Melief Cornelis J M
Vaccination for treatment and prevention of cancer in animal models.
Advances in immunology 2006;90():175-213.
2006: Schuurhuis Danita H; Fu Nathalie; Ossendorp Ferry; Melief Cornelis J M
Ins and outs of dendritic cells.
International archives of allergy and immunology 2006;140(1):53-72.
2005: Fournel Sylvie; Wieckowski Sébastien; Sun Weimin; Trouche Nathalie; Dumortier Hélène; Bianco Alberto; Chaloin Olivier; Habib Mohammed; Peter Jean-Christophe; Schneider Pascal; Vray Bernard; Toes René E; Offringa Rienk; Melief Cornelis J M; Hoebeke Johan; Guichard Gilles
C3-symmetric peptide scaffolds are functional mimetics of trimeric CD40L.
Nature chemical biology 2005;1(7):377-82.
2005: Vambutas A; DeVoti J; Nouri M; Drijfhout J W; Lipford G B; Bonagura V R; van der Burg S H; Melief C J M
Therapeutic vaccination with papillomavirus E6 and E7 long peptides results in the control of both established virus-induced lesions and latently infected sites in a pre-clinical cottontail rabbit papillomavirus model.
Vaccine 2005;23(45):5271-80.
2005: Boonman Zita F H M; van Mierlo Geertje J D; Fransen Marieke F; de Keizer Rob J W; Jager Martine J; Melief Cornelis J M; Toes René E M
Maintenance of immune tolerance depends on normal tissue homeostasis.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(7):4247-54.
2005: Melief Cornelis J M
Cancer immunology: cat and mouse games.
Nature 2005;437(7055):41-2.
2005: den Boer Annemieke Th; van Mierlo Geertje J D; Fransen Marieke F; Melief Cornelis J M; Offringa Rienk; Toes René E M
CD4+ T cells are able to promote tumor growth through inhibition of tumor-specific CD8+ T-cell responses in tumor-bearing hosts.
Cancer research 2005;65(15):6984-9.
2005: van Poelgeest Mariëtte I E; van Seters Manon; van Beurden Marc; Kwappenberg Kitty M C; Heijmans-Antonissen Claudia; Drijfhout Jan W; Melief Cornelis J M; Kenter Gemma G; Helmerhorst Theo J M; Offringa Rienk; van der Burg Sjoerd H
Detection of human papillomavirus (HPV) 16-specific CD4+ T-cell immunity in patients with persistent HPV16-induced vulvar intraepithelial neoplasia in relation to clinical impact of imiquimod treatment.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(14):5273-80.
2005: Bos Rinke; van Duikeren Suzanne; van Hall Thorbald; Kaaijk Patricia; Taubert Richard; Kyewski Bruno; Klein Ludger; Melief Cornelis J M; Offringa Rienk
Expression of a natural tumor antigen by thymic epithelial cells impairs the tumor-protective CD4+ T-cell repertoire.
Cancer research 2005;65(14):6443-9.
2005: Dumortier Hélène; van Mierlo Geertje J D; Egan Deirdre; van Ewijk Willem; Toes René E M; Offringa Rienk; Melief Cornelis J M
Antigen presentation by an immature myeloid dendritic cell line does not cause CTL deletion in vivo, but generates CD8+ central memory-like T cells that can be rescued for full effector function.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(2):855-63.
2005: Melief Cornelis J M
Safety in numbers.
European journal of human genetics : EJHG 2005;13(7):795-6.
2005: Ossendorp Ferry; Fu Nathalie; Camps Marcel; Granucci Francesca; Gobin Sam J P; van den Elsen Peter J; Schuurhuis Danita; Adema Gosse J; Lipford Grayson B; Chiba Tomoki; Sijts Alice; Kloetzel Peter-M; Ricciardi-Castagnoli Paola; Melief Cornelis J M
Differential expression regulation of the alpha and beta subunits of the PA28 proteasome activator in mature dendritic cells.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(12):7815-22.
2005: Melief Cornelis J M
Escort service for cross-priming.
Nature immunology 2005;6(6):543-4.
2005: Sandel Maro H; Dadabayev Alisher R; Menon Anand G; Morreau Hans; Melief Cornelis J M; Offringa Rienk; van der Burg Sjoerd H; Janssen-van Rhijn Connie M; Ensink N Geeske; Tollenaar Rob A E M; van de Velde Cornelis J H; Kuppen Peter J K
Prognostic value of tumor-infiltrating dendritic cells in colorectal cancer: role of maturation status and intratumoral localization.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(7):2576-82.
2005: de Jong Annemieke; van der Hulst Jeanette M; Kenter Gemma G; Drijfhout Jan Wouter; Franken Kees L M C; Vermeij Pieter; Offringa Rienk; van der Burg Sjoerd H; Melief Cornelis J M
Rapid enrichment of human papillomavirus (HPV)-specific polyclonal T cell populations for adoptive immunotherapy of cervical cancer.
International journal of cancer. Journal international du cancer 2005;114(2):274-82.
2005: Bots Michael; Kolfschoten Ingrid G M; Bres Sandra A; Rademaker Mirjam T G A; de Roo Guido M; Krüse Margreet; Franken Kees L M C; Hahne Michael; Froelich Christopher J; Melief Cornelis J M; Offringa Rienk; Medema Jan Paul
SPI-CI and SPI-6 cooperate in the protection from effector cell-mediated cytotoxicity.
Blood 2005;105(3):1153-61.
2004: van Mierlo Geertje J D; Boonman Zita F H M; Dumortier Hélène M H; den Boer Annemieke Th; Fransen Marieke F; Nouta Jan; van der Voort Ellen I H; Offringa Rienk; Toes René E M; Melief Cornelis J M
Activation of dendritic cells that cross-present tumor-derived antigen licenses CD8+ CTL to cause tumor eradication.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(11):6753-9.
2004: Welters Marij J P; Filippov Dmitri V; van den Eeden Susan J F; Franken Kees L M C; Nouta Jan; Valentijn A Rob P M; van der Marel Gijs A; Overkleeft Hermen S; Lipford Grayson; Offringa Rienk; Melief Cornelis J M; van Boom Jacques H; van der Burg Sjoerd H; Drijfhout Jan Wouter
Chemically synthesized protein as tumour-specific vaccine: immunogenicity and efficacy of synthetic HPV16 E7 in the TC-1 mouse tumour model.
Vaccine 2004;23(3):305-11.
2004: Rea Delphine; Laface Drake; Hutchins Beth; Kwappenberg Kitty; Melief Cornelis J M; Hoeben Rob C; Offringa Rienk
Recombinant adenovirus-transduced human dendritic cells engineered to secrete interleukin-10 (IL-10) suppress Th1-type responses while selectively activating IL-10-producing CD4+ T cells.
Human immunology 2004;65(11):1344-55.
2004: Dadabayev A R; Sandel M H; Menon A G; Morreau H; Melief C J M; Offringa R; van der Burg S H; Janssen-van Rhijn C; Ensink N G; Tollenaar R A E M; van de Velde C J H; Kuppen P J K
Dendritic cells in colorectal cancer correlate with other tumor-infiltrating immune cells.
Cancer immunology, immunotherapy : CII 2004;53(11):978-86.
2004: Kessler Jan H; Benckhuijsen Willemien E; Mutis Tuna; Melief Cornelis J M; van der Burg Sjoerd H; Drijfhout Jan W
Competition-based cellular peptide binding assay for HLA class I.
Current protocols in immunology / edited by John E. Coligan ... [et al.] 2004;Chapter 18():Unit 18.12.
2004: de Jong Annemieke; van Poelgeest Mariëtte I E; van der Hulst Jeanette M; Drijfhout Jan Wouter; Fleuren Gert Jan; Melief Cornelis J M; Kenter Gemma; Offringa Rienk; van der Burg Sjoerd H
Human papillomavirus type 16-positive cervical cancer is associated with impaired CD4+ T-cell immunity against early antigens E2 and E6.
Cancer research 2004;64(15):5449-55.
2004: den Boer Annemieke Th; van Mierlo Geertje J D; Fransen Marieke F; Melief Cornelis J M; Offringa Rienk; Toes René E M
The tumoricidal activity of memory CD8+ T cells is hampered by persistent systemic antigen, but full functional capacity is regained in an antigen-free environment.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(10):6074-9.
2004: Figdor Carl G; de Vries I Jolanda M; Lesterhuis W Joost; Melief Cornelis J M
Dendritic cell immunotherapy: mapping the way.
Nature medicine 2004;10(5):475-80.
2004: Sutmuller Roger P M; Offringa Rienk; Melief Cornelis J M
Revival of the regulatory T cell: new targets for drug development.
Drug discovery today 2004;9(7):310-6.
2004: Boonman Zita F H M; van Mierlo Geertje J D; Fransen Marieke F; Franken Kees L M C; Offringa Rienk; Melief Cornelis J M; Jager Martine J; Toes René E M
Intraocular tumor antigen drains specifically to submandibular lymph nodes, resulting in an abortive cytotoxic T cell reaction.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(3):1567-74.
2003: Ossevoort M; Visser B M J; van den Wollenberg D J M; van der Voort E I H; Offringa R; Melief C J M; Toes R E M; Hoeben R C
Creation of immune 'stealth' genes for gene therapy through fusion with the Gly-Ala repeat of EBNA-1.
Gene therapy 2003;10(24):2020-8.
2003: van der Burg Sjoerd H; Menon Anand G; Redeker Anke; Franken Kees L M C; Drijfhout Jan W; Tollenaar Rob A E M; Hartgrink Henk H; van de Velde Cornelis J H; Kuppen Peter J K; Melief Cornelis J M; Offringa Rienk
Magnitude and polarization of P53-specific T-helper immunity in connection to leukocyte infiltration of colorectal tumors.
International journal of cancer. Journal international du cancer 2003;107(3):425-33.
2003: Melief Cornelis J M
Mini-review: Regulation of cytotoxic T lymphocyte responses by dendritic cells: peaceful coexistence of cross-priming and direct priming?
European journal of immunology 2003;33(10):2645-54.
2003: Menon Anand G; Kuppen Peter J K; van der Burg Sjoerd H; Offringa Rienk; Bonnet Marie Claude; Harinck Bert I J; Tollenaar Rob A E M; Redeker Anke; Putter Hein; Moingeon Philippe; Morreau Hans; Melief Cornelis J M; van de Velde Cornelis J H
Safety of intravenous administration of a canarypox virus encoding the human wild-type p53 gene in colorectal cancer patients.
Cancer gene therapy 2003;10(7):509-17.
2003: Morgan Mary E; Sutmuller Roger P M; Witteveen Hendrik J; van Duivenvoorde Leonie M; Zanelli Eric; Melief Cornelis J M; Snijders Alies; Offringa Rienk; de Vries René R P; Toes René E M
CD25+ cell depletion hastens the onset of severe disease in collagen-induced arthritis.
Arthritis and rheumatism 2003;48(5):1452-60.
2003: Welters Marij J P; de Jong Annemieke; van den Eeden Susan J F; van der Hulst Jeanette M; Kwappenberg Kitty M C; Hassane Sabrin; Franken Kees L M C; Drijfhout Jan Wouter; Fleuren Gert Jan; Kenter Gemma; Melief Cornelis J M; Offringa Rienk; van der Burg Sjoerd H
Frequent display of human papillomavirus type 16 E6-specific memory t-Helper cells in the healthy population as witness of previous viral encounter.
Cancer research 2003;63(3):636-41.
2003: Kessler Jan H; Mommaas Bregje; Mutis Tuna; Huijbers Ivo; Vissers Debby; Benckhuijsen Willemien E; Schreuder Geziena M Th; Offringa Rienk; Goulmy Els; Melief Cornelis J M; van der Burg Sjoerd H; Drijfhout Jan W
Competition-based cellular peptide binding assays for 13 prevalent HLA class I alleles using fluorescein-labeled synthetic peptides.
Human immunology 2003;64(2):245-55.
2003: Offringa R; de Jong A; Toes R E M; van der Burg S H; Melief C J M
Interplay between human papillomaviruses and dendritic cells.
Current topics in microbiology and immunology 2003;276():215-40.
2002: van der Burg Sjoerd H; de Jong Annemieke; Welters Marij J P; Offringa Rienk; Melief Cornelis J M
The status of HPV16-specific T-cell reactivity in health and disease as a guide to HPV vaccine development.
Virus research 2002;89(2):275-84.
2002: Zwaveling Sander; Vierboom Michel P M; Ferreira Mota Sandra C; Hendriks Jennifer A; Ooms Marlies E; Sutmuller Roger P M; Franken Kees L M C; Nijman Hans W; Ossendorp Ferry; Van Der Burg Sjoerd H; Offringa Rienk; Melief Cornelis J M
Antitumor efficacy of wild-type p53-specific CD4(+) T-helper cells.
Cancer research 2002;62(21):6187-93.
2002: Melief Cornelis J M; Van Der Burg Sjoerd H; Toes Rene E M; Ossendorp Ferry; Offringa Rienk
Effective therapeutic anticancer vaccines based on precision guiding of cytolytic T lymphocytes.
Immunological reviews 2002;188():177-82.
2002: Schepers Koen; Toebes Mireille; Sotthewes Gitte; Vyth-Dreese Florry A; Dellemijn Trees A M; Melief Cornelis J M; Ossendorp Ferry; Schumacher Ton N M
Differential kinetics of antigen-specific CD4+ and CD8+ T cell responses in the regression of retrovirus-induced sarcomas.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(6):3191-9.
2002: Zwaveling Sander; Ferreira Mota Sandra C; Nouta Jan; Johnson Mark; Lipford Grayson B; Offringa Rienk; van der Burg Sjoerd H; Melief Cornelis J M
Established human papillomavirus type 16-expressing tumors are effectively eradicated following vaccination with long peptides.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(1):350-8.
2002: van der Burg Sjoerd H; Menon Anand G; Redeker Anke; Bonnet Marie-Claude; Drijfhout Jan Wouter; Tollenaar Rob A E M; van de Velde Cornelis J H; Moingeon Philippe; Kuppen Peter J K; Offringa Rienk; Melief Cornelis J M
Induction of p53-specific immune responses in colorectal cancer patients receiving a recombinant ALVAC-p53 candidate vaccine.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(5):1019-27.
2002: Diehl Linda; van Mierlo Geertje J D; den Boer Annemieke T; van der Voort Ellen; Fransen Marieke; van Bostelen Liesbeth; Krimpenfort Paul; Melief Cornelis J M; Mittler Robert; Toes Rene E M; Offringa Rienk
In vivo triggering through 4-1BB enables Th-independent priming of CTL in the presence of an intact CD28 costimulatory pathway.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(8):3755-62.
2002: van Mierlo Geertje J D; den Boer Annemieke Th; Medema Jan Paul; van der Voort Ellen I H; Fransen Marieke F; Offringa Rienk; Melief Cornelis J M; Toes Rene E M
CD40 stimulation leads to effective therapy of CD40(-) tumors through induction of strong systemic cytotoxic T lymphocyte immunity.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(8):5561-6.
2002: Schuurhuis Danita H; Ioan-Facsinay Andreea; Nagelkerken Bas; van Schip Jolien J; Sedlik Christine; Melief Cornelis J M; Verbeek J Sjef; Ossendorp Ferry
Antigen-antibody immune complexes empower dendritic cells to efficiently prime specific CD8+ CTL responses in vivo.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(5):2240-6.
2002: Heukamp Lukas C; van Hall Thorbald; Ossendorp Ferry; Burchell Joy M; Melief Cornelis J M; Taylor-Papadimitriou Joyce; Offringa Rienk
Effective immunotherapy of cancer in MUC1-transgenic mice using clonal cytotoxic T lymphocytes directed against an immunodominant MUC1 epitope.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2002;25(1):46-56.
2002: de Jong Annemieke; van der Burg Sjoerd H; Kwappenberg Kitty M C; van der Hulst Jeanette M; Franken Kees L M C; Geluk Annemieke; van Meijgaarden Krista E; Drijfhout Jan Wouter; Kenter Gemma; Vermeij Pieter; Melief Cornelis J M; Offringa Rienk
Frequent detection of human papillomavirus 16 E2-specific T-helper immunity in healthy subjects.
Cancer research 2002;62(2):472-9.
2002: Zwaveling Sander; Van der Burg Sjoerd H; Menon Anand G; Melief Cornelis J M; Offringa Rienk
Immunotherapy of cancer through targeting of the p53 tumor antigen.
Archivum immunologiae et therapiae experimentalis 2002;50(5):297-305.
2001: Schurmans L R; Diehl L; den Boer A T; Sutmuller R P; Boonman Z F; Medema J P; van der Voort E I; Laman J; Melief C J; Jager M J; Toes R E
Rejection of intraocular tumors by CD4(+) T cells without induction of phthisis.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(10):5832-7.
2001: Stanislawski T; Voss R H; Lotz C; Sadovnikova E; Willemsen R A; Kuball J; Ruppert T; Bolhuis R L; Melief C J; Huber C; Stauss H J; Theobald M
Circumventing tolerance to a human MDM2-derived tumor antigen by TCR gene transfer.
Nature immunology 2001;2(10):962-70.
2001: Medema J P; de Jong J; Peltenburg L T; Verdegaal E M; Gorter A; Bres S A; Franken K L; Hahne M; Albar J P; Melief C J; Offringa R
Blockade of the granzyme B/perforin pathway through overexpression of the serine protease inhibitor PI-9/SPI-6 constitutes a mechanism for immune escape by tumors.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(20):11515-20.
2001: Sutmuller R P; van Duivenvoorde L M; van Elsas A; Schumacher T N; Wildenberg M E; Allison J P; Toes R E; Offringa R; Melief C J
Synergism of cytotoxic T lymphocyte-associated antigen 4 blockade and depletion of CD25(+) regulatory T cells in antitumor therapy reveals alternative pathways for suppression of autoreactive cytotoxic T lymphocyte responses.
The Journal of experimental medicine 2001;194(6):823-32.
2001: Medema J P; Schuurhuis D H; Rea D; van Tongeren J; de Jong J; Bres S A; Laban S; Toes R E; Toebes M; Schumacher T N; Bladergroen B A; Ossendorp F; Kummer J A; Melief C J; Offringa R
Expression of the serpin serine protease inhibitor 6 protects dendritic cells from cytotoxic T lymphocyte-induced apoptosis: differential modulation by T helper type 1 and type 2 cells.
The Journal of experimental medicine 2001;194(5):657-67.
2001: den Boer A T; Diehl L; van Mierlo G J; van der Voort E I; Fransen M F; Krimpenfort P; Melief C J; Offringa R; Toes R E
Longevity of antigen presentation and activation status of APC are decisive factors in the balance between CTL immunity versus tolerance.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(5):2522-8.
2001: van Elsas A; Sutmuller R P; Hurwitz A A; Ziskin J; Villasenor J; Medema J P; Overwijk W W; Restifo N P; Melief C J; Offringa R; Allison J P
Elucidating the autoimmune and antitumor effector mechanisms of a treatment based on cytotoxic T lymphocyte antigen-4 blockade in combination with a B16 melanoma vaccine: comparison of prophylaxis and therapy.
The Journal of experimental medicine 2001;194(4):481-9.
2001: van der Burg S H; Kwappenberg K M; O'Neill T; Brandt R M; Melief C J; Hickling J K; Offringa R
Pre-clinical safety and efficacy of TA-CIN, a recombinant HPV16 L2E6E7 fusion protein vaccine, in homologous and heterologous prime-boost regimens.
Vaccine 2001;19(27):3652-60.
2001: Rea D; Havenga M J; van Den Assem M; Sutmuller R P; Lemckert A; Hoeben R C; Bout A; Melief C J; Offringa R
Highly efficient transduction of human monocyte-derived dendritic cells with subgroup B fiber-modified adenovirus vectors enhances transgene-encoded antigen presentation to cytotoxic T cells.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(8):5236-44.
2001: Rea D; Johnson M E; Havenga M J; Melief C J; Offringa R
Strategies for improved antigen delivery into dendritic cells.
Trends in molecular medicine 2001;7(3):91-4.
2001: van der Burg S H; Ressing M E; Kwappenberg K M; de Jong A; Straathof K; de Jong J; Geluk A; van Meijgaarden K E; Franken K L; Ottenhoff T H; Fleuren G J; Kenter G; Melief C J; Offringa R
Natural T-helper immunity against human papillomavirus type 16 (HPV16) E7-derived peptide epitopes in patients with HPV16-positive cervical lesions: identification of 3 human leukocyte antigen class II-restricted epitopes.
International journal of cancer. Journal international du cancer 2001;91(5):612-8.
2001: Heukamp L C; van der Burg S H; Drijfhout J W; Melief C J; Taylor-Papadimitriou J; Offringa R
Identification of three non-VNTR MUC1-derived HLA-A*0201-restricted T-cell epitopes that induce protective anti-tumor immunity in HLA-A2/K(b)-transgenic mice.
International journal of cancer. Journal international du cancer 2001;91(3):385-92.
2001: van der Burg S H; de Cock K; Menon A G; Franken K L; Palmen M; Redeker A; Drijfhout J; Kuppen P J; van de Velde C; Erdile L; Tollenaar R A; Melief C J; Offringa R
Long lasting p53-specific T cell memory responses in the absence of anti-p53 antibodies in patients with resected primary colorectal cancer.
European journal of immunology 2001;31(1):146-55.
2001: Kessler J H; Beekman N J; Bres-Vloemans S A; Verdijk P; van Veelen P A; Kloosterman-Joosten A M; Vissers D C; ten Bosch G J; Kester M G; Sijts A; Wouter Drijfhout J; Ossendorp F; Offringa R; Melief C J
Efficient identification of novel HLA-A(*)0201-presented cytotoxic T lymphocyte epitopes in the widely expressed tumor antigen PRAME by proteasome-mediated digestion analysis.
The Journal of experimental medicine 2001;193(1):73-88.
2000: Sutmuller R P; Schurmans L R; van Duivenvoorde L M; Tine J A; van Der Voort E I; Toes R E; Melief C J; Jager M J; Offringa R
Adoptive T cell immunotherapy of human uveal melanoma targeting gp100.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(12):7308-15.
2000: van Bergen J; Camps M; Offringa R; Melief C J; Ossendorp F; Koning F
Superior tumor protection induced by a cellular vaccine carrying a tumor-specific T helper epitope by genetic exchange of the class II-associated invariant chain peptide.
Cancer research 2000;60(22):6427-33.
2000: Vierboom M P; Zwaveling S; Bos GMJ; Ooms M; Krietemeijer G M; Melief C J; Offringa R
High steady-state levels of p53 are not a prerequisite for tumor eradication by wild-type p53-specific cytotoxic T lymphocytes.
Cancer research 2000;60(19):5508-13.
2000: Ossendorp F; Toes R E; Offringa R; van der Burg S H; Melief C J
Importance of CD4(+) T helper cell responses in tumor immunity.
Immunology letters 2000;74(1):75-9.
2000: van Hall T; Sijts A; Camps M; Offringa R; Melief C; Kloetzel P M; Ossendorp F
Differential influence on cytotoxic T lymphocyte epitope presentation by controlled expression of either proteasome immunosubunits or PA28.
The Journal of experimental medicine 2000;192(4):483-94.
2000: Schuurhuis D H; Laban S; Toes R E; Ricciardi-Castagnoli P; Kleijmeer M J; van der Voort E I; Rea D; Offringa R; Geuze H J; Melief C J; Ossendorp F
Immature dendritic cells acquire CD8(+) cytotoxic T lymphocyte priming capacity upon activation by T helper cell-independent or -dependent stimuli.
The Journal of experimental medicine 2000;192(1):145-50.
2000: van Hall T; van Bergen J; van Veelen P A; Kraakman M; Heukamp L C; Koning F; Melief C J; Ossendorp F; Offringa R
Identification of a novel tumor-specific CTL epitope presented by RMA, EL-4, and MBL-2 lymphomas reveals their common origin.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(2):869-77.
2000: Vierboom M P; Bos G M; Ooms M; Offringa R; Melief C J
Cyclophosphamide enhances anti-tumor effect of wild-type p53-specific CTL.
International journal of cancer. Journal international du cancer 2000;87(2):253-60.
2000: Offringa R; Vierboom M P; van der Burg S H; Erdile L; Melief C J
p53: a potential target antigen for immunotherapy of cancer.
Annals of the New York Academy of Sciences 2000;910():223-33; discussion 233-6.
2000: Leeksma O C; Kessler J H; Huijbers I J; Ten Bosch G J; Melief C J
BCR-ABL directed immunotherapy: a virtual reality?
Leukemia & lymphoma 2000;38(1-2):175-81.
2000: Rea D; van Kooten C; van Meijgaarden K E; Ottenhoff T H; Melief C J; Offringa R
Glucocorticoids transform CD40-triggering of dendritic cells into an alternative activation pathway resulting in antigen-presenting cells that secrete IL-10.
Blood 2000;95(10):3162-7.
2000: Sijts A J; Standera S; Toes R E; Ruppert T; Beekman N J; van Veelen P A; Ossendorp F A; Melief C J; Kloetzel P M
MHC class I antigen processing of an adenovirus CTL epitope is linked to the levels of immunoproteasomes in infected cells.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(9):4500-6.
2000: Ressing M E; van Driel W J; Brandt R M; Kenter G G; de Jong J H; Bauknecht T; Fleuren G J; Hoogerhout P; Offringa R; Sette A; Celis E; Grey H; Trimbos B J; Kast W M; Melief C J
Detection of T helper responses, but not of human papillomavirus-specific cytotoxic T lymphocyte responses, after peptide vaccination of patients with cervical carcinoma.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2000;23(2):255-66.
2000: Beekman N J; van Veelen P A; van Hall T; Neisig A; Sijts A; Camps M; Kloetzel P M; Neefjes J J; Melief C J; Ossendorp F
Abrogation of CTL epitope processing by single amino acid substitution flanking the C-terminal proteasome cleavage site.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(4):1898-905.
2000: Diehl L; Den Boer A T; van der Voort E I; Melief C J; Offringa R; Toes R E
The role of CD40 in peripheral T cell tolerance and immunity.
Journal of molecular medicine (Berlin, Germany) 2000;78(7):363-71.
2000: Melief C J; Toes R E; Medema J P; van der Burg S H; Ossendorp F; Offringa R
Strategies for immunotherapy of cancer.
Advances in immunology 2000;75():235-82.
1999: Rea D; Schagen F H; Hoeben R C; Mehtali M; Havenga M J; Toes R E; Melief C J; Offringa R
Adenoviruses activate human dendritic cells without polarization toward a T-helper type 1-inducing subset.
Journal of virology 1999;73(12):10245-53.
1999: Schurmans L R; den Boer A T; Diehl L; van der Voort E I; Kast W M; Melief C J; Toes R E; Jager M J
Successful immunotherapy of an intraocular tumor in mice.
Cancer research 1999;59(20):5250-4.
1999: Medema J P; de Jong J; van Hall T; Melief C J; Offringa R
Immune escape of tumors in vivo by expression of cellular FLICE-inhibitory protein.
The Journal of experimental medicine 1999;190(7):1033-8.
1999: ten Bosch G J; Kessler J H; Joosten A M; Bres-Vloemans A A; Geluk A; Godthelp B C; van Bergen J; Melief C J; Leeksma O C
A BCR-ABL oncoprotein p210b2a2 fusion region sequence is recognized by HLA-DR2a restricted cytotoxic T lymphocytes and presented by HLA-DR matched cells transfected with an Ii(b2a2) construct.
Blood 1999;94(3):1038-45.
1999: Kammer A R; van der Burg S H; Grabscheid B; Hunziker I P; Kwappenberg K M; Reichen J; Melief C J; Cerny A
Molecular mimicry of human cytochrome P450 by hepatitis C virus at the level of cytotoxic T cell recognition.
The Journal of experimental medicine 1999;190(2):169-76.
1999: Diehl L; den Boer A T; Schoenberger S P; van der Voort E I; Schumacher T N; Melief C J; Offringa R; Toes R E
CD40 activation in vivo overcomes peptide-induced peripheral cytotoxic T-lymphocyte tolerance and augments anti-tumor vaccine efficacy.
Nature medicine 1999;5(7):774-9.
1999: Verdijk R M; Mutis T; Esendam B; Kamp J; Melief C J; Brand A; Goulmy E
Polyriboinosinic polyribocytidylic acid (poly(I:C)) induces stable maturation of functionally active human dendritic cells.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(1):57-61.
1999: Melief C J; Schoenberger S; Toes R; Offringa R
Cytotoxic T lymphocyte priming versus cytotoxic T lymphocyte tolerance induction: a delicate balancing act involving dendritic cells.
Haematologica 1999;84 Suppl EHA-4():26-7.
1999: van Driel W J; Ressing M E; Kenter G G; Brandt R M; Krul E J; van Rossum A B; Schuuring E; Offringa R; Bauknecht T; Tamm-Hermelink A; van Dam P A; Fleuren G J; Kast W M; Melief C J; Trimbos J B
Vaccination with HPV16 peptides of patients with advanced cervical carcinoma: clinical evaluation of a phase I-II trial.
European journal of cancer (Oxford, England : 1990) 1999;35(6):946-52.
1999: Krul E J; Schipper R F; Schreuder G M; Fleuren G J; Kenter G G; Melief C J
HLA and susceptibility to cervical neoplasia.
Human immunology 1999;60(4):337-42.
1999: Ressing M E; de Jong J H; Brandt R M; Drijfhout J W; Benckhuijsen W E; Schreuder G M; Offringa R; Kast W M; Melief C J
Differential binding of viral peptides to HLA-A2 alleles. Implications for human papillomavirus type 16 E7 peptide-based vaccination against cervical carcinoma.
European journal of immunology 1999;29(4):1292-303.
1999: Toes R E; Ossendorp F; Offringa R; Melief C J
CD4 T cells and their role in antitumor immune responses.
The Journal of experimental medicine 1999;189(5):753-6.
1999: van Driel W J; Kenter G G; Fleuren G J; Melief C J; Trimbos B J
Immunotherapeutic strategies for cervical squamous carcinoma.
Hematology/oncology clinics of North America 1999;13(1):259-73.
1999: van der Burg S H; Kwappenberg K M; Geluk A; van der Kruk M; Pontesilli O; Hovenkamp E; Franken K L; van Meijgaarden K E; Drijfhout J W; Ottenhoff T H; Melief C J; Offringa R
Identification of a conserved universal Th epitope in HIV-1 reverse transcriptase that is processed and presented to HIV-specific CD4+ T cells by at least four unrelated HLA-DR molecules.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(1):152-60.
1998: ten Bosch G J; Kessler J H; Blom J; Joosten A M; Gambacorti-Passerini C; Melief C J; Leeksma O C
BCR-ABL oncoprotein is expressed by platelets from CML patients and associated with a special pattern of CrkL phosphorylation.
British journal of haematology 1998;103(4):1109-15.
1998: Toes R E; Schoenberger S P; van der Voort E I; Offringa R; Melief C J
CD40-CD40Ligand interactions and their role in cytotoxic T lymphocyte priming and anti-tumor immunity.
Seminars in immunology 1998;10(6):443-8.
1998: Vierboom M P; Feltkamp M C; Neisig A; Drijfhout J W; ter Schegget J; Neefjes J J; Melief C J; Kast W M
Peptide vaccination with an anchor-replaced CTL epitope protects against human papillomavirus type 16-induced tumors expressing the wild-type epitope.
Journal of immunotherapy (Hagerstown, Md. : 1997) 1998;21(6):399-408.
1998: De Bruijn M L; Greenstone H L; Vermeulen H; Melief C J; Lowy D R; Schiller J T; Kast W M
L1-specific protection from tumor challenge elicited by HPV16 virus-like particles.
Virology 1998;250(2):371-6.
1998: Schoenberger S P; van der Voort E I; Krietemeijer G M; Offringa R; Melief C J; Toes R E
Cross-priming of CTL responses in vivo does not require antigenic peptides in the endoplasmic reticulum of immunizing cells.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(8):3808-12.
1998: Klein M R; van der Burg S H; Hovenkamp E; Holwerda A M; Drijfhout J W; Melief C J; Miedema F
Characterization of HLA-B57-restricted human immunodeficiency virus type 1 Gag- and RT-specific cytotoxic T lymphocyte responses.
The Journal of general virology 1998;79 ( Pt 9)():2191-201.
1998: Mutis T; Schrama E; Melief C J; Goulmy E
CD80-Transfected acute myeloid leukemia cells induce primary allogeneic T-cell responses directed at patient specific minor histocompatibility antigens and leukemia-associated antigens.
Blood 1998;92(5):1677-84.
1998: Schoenberger S P; Jonges L E; Mooijaart R J; Hartgers F; Toes R E; Kast W M; Melief C J; Offringa R
Efficient direct priming of tumor-specific cytotoxic T lymphocyte in vivo by an engineered APC.
Cancer research 1998;58(14):3094-100.
1998: van Hall T; van de Rhee N E; Schoenberger S P; Vierboom M P; Verreck F A; Melief C J; Offringa R
Cryptic open reading frames in plasmid vector backbone sequences can provide highly immunogenic cytotoxic T-lymphocyte epitopes.
Cancer research 1998;58(14):3087-93.
1998: Schoenberger S P; Toes R E; van der Voort E I; Offringa R; Melief C J
T-cell help for cytotoxic T lymphocytes is mediated by CD40-CD40L interactions.
Nature 1998;393(6684):480-3.
1998: Toes R E; van der Voort E I; Schoenberger S P; Drijfhout J W; van Bloois L; Storm G; Kast W M; Offringa R; Melief C J
Enhancement of tumor outgrowth through CTL tolerization after peptide vaccination is avoided by peptide presentation on dendritic cells.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(9):4449-56.
1998: Ossendorp F; Mengedé E; Camps M; Filius R; Melief C J
Specific T helper cell requirement for optimal induction of cytotoxic T lymphocytes against major histocompatibility complex class II negative tumors.
The Journal of experimental medicine 1998;187(5):693-702.
1998: De Bruijn M L; Schuurhuis D H; Vierboom M P; Vermeulen H; de Cock K A; Ooms M E; Ressing M E; Toebes M; Franken K L; Drijfhout J W; Ottenhoff T H; Offringa R; Melief C J
Immunization with human papillomavirus type 16 (HPV16) oncoprotein-loaded dendritic cells as well as protein in adjuvant induces MHC class I-restricted protection to HPV16-induced tumor cells.
Cancer research 1998;58(4):724-31.
1998: Neisig A; Melief C J; Neefjes J
Reduced cell surface expression of HLA-C molecules correlates with restricted peptide binding and stable TAP interaction.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(1):171-9.
1997: Toes R E; Hoeben R C; van der Voort E I; Ressing M E; van der Eb A J; Melief C J; Offringa R
Protective anti-tumor immunity induced by vaccination with recombinant adenoviruses encoding multiple tumor-associated cytotoxic T lymphocyte epitopes in a string-of-beads fashion.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(26):14660-5.
1997: Toes R E; Schoenberger S P; van der Voort E I; Kast W M; Hoeben R C; Melief C J; Offringa R
Activation or frustration of anti-tumor responses by T-cell-based immune modulation.
Seminars in immunology 1997;9(5):323-7.
1997: van der Burg S H; Klein M R; Pontesilli O; Holwerda A M; Drijfhout J W; Kast W M; Miedema F; Melief C J
HIV-1 reverse transcriptase-specific CTL against conserved epitopes do not protect against progression to AIDS.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(7):3648-54.
1997: Visseren M J; van der Burg S H; Hawes G E; van der Voort E I; van den Elsen P J; Melief C J
Affinity, specificity and T-cell-receptor diversity of melanoma-specific CTL generated in vitro against a single tyrosinase epitope.
International journal of cancer. Journal international du cancer 1997;72(6):1122-8.
1997: Visseren M J; van der Burg S H; van der Voort E I; Brandt R M; Schrier P I; van der Bruggen P; Boon T; Melief C J; Kast W M
Identification of HLA-A*0201-restricted CTL epitopes encoded by the tumor-specific MAGE-2 gene product.
International journal of cancer. Journal international du cancer 1997;73(1):125-30.
1997: Vierboom M P; Nijman H W; Offringa R; van der Voort E I; van Hall T; van den Broek L; Fleuren G J; Kenemans P; Kast W M; Melief C J
Tumor eradication by wild-type p53-specific cytotoxic T lymphocytes.
The Journal of experimental medicine 1997;186(5):695-704.
1997: Mutis T; Schrama E; van Luxemburg-Heijs S A; Falkenburg J H; Melief C J; Goulmy E
HLA class II restricted T-cell reactivity to a developmentally regulated antigen shared by leukemic cells and CD34+ early progenitor cells.
Blood 1997;90(3):1083-90.
1997: Ras E; van der Burg S H; Zegveld S T; Brandt R M; Kuppen P J; Offringa R; Warnarr S O; van de Velde C J; Melief C J
Identification of potential HLA-A *0201 restricted CTL epitopes derived from the epithelial cell adhesion molecule (Ep-CAM) and the carcinoembryonic antigen (CEA).
Human immunology 1997;53(1):81-9.
1997: De Bruijn M L; Schuurhuis D H; Vermeulen H; de Cock K A; Melief C J
Processing of exogenous protein antigen by murine dendritic cells for presentation to cytotoxic T lymphocytes.
Advances in experimental medicine and biology 1997;417():213-20.
1996: van Driel W J; Ressing M E; Brandt R M; Toes R E; Fleuren G J; Trimbos J B; Kast W M; Melief C J
The current status of therapeutic HPV vaccine.
Annals of medicine 1996;28(6):471-7.
1996: Kono K; Ressing M E; Brandt R M; Melief C J; Potkul R K; Andersson B; Petersson M; Kast W M; Kiessling R
Decreased expression of signal-transducing zeta chain in peripheral T cells and natural killer cells in patients with cervical cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 1996;2(11):1825-8.
1996: Ressing M E; Offringa R; Toes R E; Ossendorp F; de Jong J H; Brandt R M; Kast W M; Melief C J
Immunotherapy of cancer by peptide-based vaccines for the induction of tumor-specific T cell immunity.
Immunotechnology : an international journal of immunological engineering 1996;2(4):241-51.
1996: Ossevoort M A; De Bruijn M L; Van Veen K J; Kast W M; Melief C J
Peptide specificity of alloreactive CD4 positive T lymphocytes directed against a major histocompatibility complex class I disparity.
Transplantation 1996;62(10):1485-91.
1996: Bosch G J; Joosten A M; Kessler J H; Melief C J; Leeksma O C
Recognition of BCR-ABL positive leukemic blasts by human CD4+ T cells elicited by primary in vitro immunization with a BCR-ABL breakpoint peptide.
Blood 1996;88(9):3522-7.
1996: Melief C J; Offringa R; Toes R E; Kast W M
Peptide-based cancer vaccines.
Current opinion in immunology 1996;8(5):651-7.
1996: Hooijberg E; Visseren M J; van den Berk P C; Jellema A P; Romeijn P; Sein J J; van der Voort E I; Hekman A; Ossendorp F; Melief C J
Lysis of syngeneic tumor B cells by autoreactive cytotoxic T lymphocytes specific for a CD19 antigen-derived synthetic peptide.
Journal of immunotherapy with emphasis on tumor immunology : official journal of the Society for Biological Therapy 1996;19(5):346-56.
1996: Ossendorp F; Eggers M; Neisig A; Ruppert T; Groettrup M; Sijts A; Mengedë E; Kloetzel P M; Neefjes J; Koszinowski U; Melief C
A single residue exchange within a viral CTL epitope alters proteasome-mediated degradation resulting in lack of antigen presentation.
Immunity 1996;5(2):115-24.
1996: van Elsas A; van der Burg S H; van der Minne C E; Borghi M; Mourer J S; Melief C J; Schrier P I
Peptide-pulsed dendritic cells induce tumoricidal cytotoxic T lymphocytes from healthy donors against stably HLA-A*0201-binding peptides from the Melan-A/MART-1 self antigen.
European journal of immunology 1996;26(8):1683-9.
1996: Toes R E; Blom R J; van der Voort E; Offringa R; Melief C J; Kast W M
Protective antitumor immunity induced by immunization with completely allogeneic tumor cells.
Cancer research 1996;56(16):3782-7.
1996: Toes R E; Offringa R; Blom R J; Melief C J; Kast W M
Peptide vaccination can lead to enhanced tumor growth through specific T-cell tolerance induction.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(15):7855-60.
1996: Toes R E; Kast W M; Blom R J; Bakker S C; Offringa R; Melief C J
Efficient tumor eradication by adoptively transferred cytotoxic T-cell clones in allogeneic hosts.
International journal of cancer. Journal international du cancer 1996;66(5):686-91.
1996: Toes R E; Blom R J; Offringa R; Kast W M; Melief C J
Enhanced tumor outgrowth after peptide vaccination. Functional deletion of tumor-specific CTL induced by peptide vaccination can lead to the inability to reject tumors.
Journal of immunology (Baltimore, Md. : 1950) 1996;156(10):3911-8.
1996: van der Burg S H; Visseren M J; Brandt R M; Kast W M; Melief C J
Immunogenicity of peptides bound to MHC class I molecules depends on the MHC-peptide complex stability.
Journal of immunology (Baltimore, Md. : 1950) 1996;156(9):3308-14.
1996: Neisig A; Wubbolts R; Zang X; Melief C; Neefjes J
Allele-specific differences in the interaction of MHC class I molecules with transporters associated with antigen processing.
Journal of immunology (Baltimore, Md. : 1950) 1996;156(9):3196-206.
1996: Raposo G; Nijman H W; Stoorvogel W; Liejendekker R; Harding C V; Melief C J; Geuze H J
B lymphocytes secrete antigen-presenting vesicles.
The Journal of experimental medicine 1996;183(3):1161-72.
1996: Ressing M E; van Driel W J; Celis E; Sette A; Brandt M P; Hartman M; Anholts J D; Schreuder G M; ter Harmsel W B; Fleuren G J; Trimbos B J; Kast W M; Melief C J
Occasional memory cytotoxic T-cell responses of patients with human papillomavirus type 16-positive cervical lesions against a human leukocyte antigen-A *0201-restricted E7-encoded epitope.
Cancer research 1996;56(3):582-8.
1995: van der Burg S H; Ras E; Drijfhout J W; Benckhuijsen W E; Bremers A J; Melief C J; Kast W M
An HLA class I peptide-binding assay based on competition for binding to class I molecules on intact human B cells. Identification of conserved HIV-1 polymerase peptides binding to HLA-A*0301.
Human immunology 1995;44(4):189-98.
1995: Houbiers J G; van der Burg S H; van de Watering L M; Tollenaar R A; Brand A; van de Velde C J; Melief C J
Antibodies against p53 are associated with poor prognosis of colorectal cancer.
British journal of cancer 1995;72(3):637-41.
1995: Feltkamp M C; Vreugdenhil G R; Vierboom M P; Ras E; van der Burg S H; ter Schegget J; Melief C J; Kast W M
Cytotoxic T lymphocytes raised against a subdominant epitope offered as a synthetic peptide eradicate human papillomavirus type 16-induced tumors.
European journal of immunology 1995;25(9):2638-42.
1995: Ossevoort M A; Feltkamp M C; van Veen K J; Melief C J; Kast W M
Dendritic cells as carriers for a cytotoxic T-lymphocyte epitope-based peptide vaccine in protection against a human papillomavirus type 16-induced tumor.
Journal of immunotherapy with emphasis on tumor immunology : official journal of the Society for Biological Therapy 1995;18(2):86-94.
1995: Toes R E; Feltkamp M C; Ressing M E; Vierboom M P; Blom R J; Brandt R M; Hartman M; Offringa R; Melief C J; Kast W M
Cellular immunity against DNA tumour viruses: possibilities for peptide-based vaccines and immune escape.
Biochemical Society transactions 1995;23(3):692-6.
1995: ten Bosch G J; Toornvliet A C; Friede T; Melief C J; Leeksma O C
Recognition of peptides corresponding to the joining region of p210BCR-ABL protein by human T cells.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1995;9(8):1344-8.
1995: Feltkamp M C; Vierboom M P; Toes R E; Ossendorp F; ter Schegget J; Melief C J; Kast W M
Competition inhibition of cytotoxic T-lymphocyte (CTL) lysis, a more sensitive method to identify candidate CTL epitopes than induction of antibody-detected MHC class I stabilization.
Immunology letters 1995;47(1-2):1-8.
1995: Nijman H W; Kleijmeer M J; Ossevoort M A; Oorschot V M; Vierboom M P; van de Keur M; Kenemans P; Kast W M; Geuze H J; Melief C J
Antigen capture and major histocompatibility class II compartments of freshly isolated and cultured human blood dendritic cells.
The Journal of experimental medicine 1995;182(1):163-74.
1995: Kleijmeer M J; Ossevoort M A; van Veen C J; van Hellemond J J; Neefjes J J; Kast W M; Melief C J; Geuze H J
MHC class II compartments and the kinetics of antigen presentation in activated mouse spleen dendritic cells.
Journal of immunology (Baltimore, Md. : 1950) 1995;154(11):5715-24.
1995: Hooijberg E; Sein J J; van den Berk P C; Hart A A; van der Valk M A; Kast W M; Melief C J; Hekman A
Eradication of large human B cell tumors in nude mice with unconjugated CD20 monoclonal antibodies and interleukin 2.
Cancer research 1995;55(12):2627-34.
1995: Ressing M E; Sette A; Brandt R M; Ruppert J; Wentworth P A; Hartman M; Oseroff C; Grey H M; Melief C J; Kast W M
Human CTL epitopes encoded by human papillomavirus type 16 E6 and E7 identified through in vivo and in vitro immunogenicity studies of HLA-A*0201-binding peptides.
Journal of immunology (Baltimore, Md. : 1950) 1995;154(11):5934-43.
1995: Van Elsas A; Nijman H W; Van der Minne C E; Mourer J S; Kast W M; Melief C J; Schrier P I
Induction and characterization of cytotoxic T-lymphocytes recognizing a mutated p21ras peptide presented by HLA-A*0201.
International journal of cancer. Journal international du cancer 1995;61(3):389-96.
1995: D'Amaro J; Houbiers J G; Drijfhout J W; Brandt R M; Schipper R; Bavinck J N; Melief C J; Kast W M
A computer program for predicting possible cytotoxic T lymphocyte epitopes based on HLA class I peptide-binding motifs.
Human immunology 1995;43(1):13-8.
1995: Drijfhout J W; Brandt R M; D'Amaro J; Kast W M; Melief C J
Detailed motifs for peptide binding to HLA-A*0201 derived from large random sets of peptides using a cellular binding assay.
Human immunology 1995;43(1):1-12.
1995: Visseren M J; van Elsas A; van der Voort E I; Ressing M E; Kast W M; Schrier P I; Melief C J
CTL specific for the tyrosinase autoantigen can be induced from healthy donor blood to lyse melanoma cells.
Journal of immunology (Baltimore, Md. : 1950) 1995;154(8):3991-8.
1995: Toes R E; Offringa R; Blom R J; Brandt R M; van der Eb A J; Melief C J; Kast W M
An adenovirus type 5 early region 1B-encoded CTL epitope-mediating tumor eradication by CTL clones is down-modulated by an activated ras oncogene.
Journal of immunology (Baltimore, Md. : 1950) 1995;154(7):3396-405.
1995: Neisig A; Roelse J; Sijts A J; Ossendorp F; Feltkamp M C; Kast W M; Melief C J; Neefjes J J
Major differences in transporter associated with antigen presentation (TAP)-dependent translocation of MHC class I-presentable peptides and the effect of flanking sequences.
Journal of immunology (Baltimore, Md. : 1950) 1995;154(3):1273-9.
1995: van der Burg S H; Klein M R; van de Velde C J; Kast W M; Miedema F; Melief C J
Induction of a primary human cytotoxic T-lymphocyte response against a novel conserved epitope in a functional sequence of HIV-1 reverse transcriptase.
AIDS (London, England) 1995;9(2):121-7.
1995: Hooijberg E; van den Berk P C; Sein J J; Wijdenes J; Hart A A; de Boer R W; Melief C J; Hekman A
Enhanced antitumor effects of CD20 over CD19 monoclonal antibodies in a nude mouse xenograft model.
Cancer research 1995;55(4):840-6.
1995: Vlasveld L T; Hekman A; Vyth-Dreese F A; Melief C J; Sein J J; Voordouw A C; Dellemijn T A; Rankin E M
Treatment of low-grade non-Hodgkin's lymphoma with continuous infusion of low-dose recombinant interleukin-2 in combination with the B-cell-specific monoclonal antibody CLB-CD19.
Cancer immunology, immunotherapy : CII 1995;40(1):37-47.
1995: Ossevoort M A; Kleijmeer M J; Nijman H W; Geuze H J; Kast W M; Melief C J
Functional and ultrastructural aspects of antigen processing by dendritic cells.
Advances in experimental medicine and biology 1995;378():227-31.
1994: Feltkamp M C; Vierboom M P; Kast W M; Melief C J
Efficient MHC class I-peptide binding is required but does not ensure MHC class I-restricted immunogenicity.
Molecular immunology 1994;31(18):1391-401.
1994: Sijts E J; Leupers C J; Mengedé E A; Loenen W A; van den Elsen P J; Melief C J
Cloning of the MCF1233 murine leukemia virus and identification of sequences involved in viral tropism, oncogenicity and T cell epitope formation.
Virus research 1994;34(3):339-49.
1994: Sette A; Vitiello A; Reherman B; Fowler P; Nayersina R; Kast W M; Melief C J; Oseroff C; Yuan L; Ruppert J; Sidney J; del Guercio M F; Southwood S; Kubo R T; Chesnut R W; Grey H M; Chisari F V
The relationship between class I binding affinity and immunogenicity of potential cytotoxic T cell epitopes.
Journal of immunology (Baltimore, Md. : 1950) 1994;153(12):5586-92.
1994: Sijts A J; De Bruijn M L; Ressing M E; Nieland J D; Mengedé E A; Boog C J; Ossendorp F; Kast W M; Melief C J
Identification of an H-2 Kb-presented Moloney murine leukemia virus cytotoxic T-lymphocyte epitope that displays enhanced recognition in H-2 Db mutant bm13 mice.
Journal of virology 1994;68(9):6038-46.
1994: Toes R E; Offringa R; Feltkamp M C; Visseren M J; Schoenberger S P; Melief C J; Kast W M
Tumor rejection antigens and tumor specific cytotoxic T lymphocytes.
Behring Institute Mitteilungen 1994;(94):72-86.
1994: Nijman H W; Van der Burg S H; Vierboom M P; Houbiers J G; Kast W M; Melief C J
p53, a potential target for tumor-directed T cells.
Immunology letters 1994;40(2):171-8.
1994: Kast W M; Brandt R M; Sidney J; Drijfhout J W; Kubo R T; Grey H M; Melief C J; Sette A
Role of HLA-A motifs in identification of potential CTL epitopes in human papillomavirus type 16 E6 and E7 proteins.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(8):3904-12.
1994: Vlasveld L T; Horenblas S; Hekman A; Hilton A M; Dubbelman A C; Melief C J; Rankin E M
Phase II study of intermittent continuous infusion of low-dose recombinant interleukin-2 in advanced melanoma and renal cell cancer.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 1994;5(2):179-81.
1994: Visseren M J; Koot M; van der Voort E I; Gravestein L A; Schoenmakers H J; Kast W M; Zijlstra M; Melief C J
Production of interleukin-2 by EL4 tumor cells induces natural killer cell- and T-cell-mediated immunity.
Journal of immunotherapy with emphasis on tumor immunology : official journal of the Society for Biological Therapy 1994;15(2):119-28.
1994: Sijts A J; Ossendorp F; Mengedé E A; van den Elsen P J; Melief C J
Immunodominant mink cell focus-inducing murine leukemia virus (MuLV)-encoded CTL epitope, identified by its MHC class I-binding motif, explains MuLV-type specificity of MCF-directed cytotoxic T lymphocytes.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(1):106-16.
1994: Melief C J; Kast W M
Prospects for T cell immunotherapy of tumours by vaccination with immunodominant and subdominant peptides.
Ciba Foundation symposium 1994;187():97-104; discussion 104-12.
1993: Ossevoort M A; Sijts A J; van Veen K J; Momburg F; Hämmerling G J; Seelig A; Butcher G W; Howard J C; Kast W M; Melief C J
Differential effect of transporter Tap 2 gene introduction into RMA-S cells on viral antigen processing.
European journal of immunology 1993;23(12):3082-8.
1993: Melief C J; Kast W M
Potential immunogenicity of oncogene and tumor suppressor gene products.
Current opinion in immunology 1993;5(5):709-13.
1993: Houbiers J G; Nijman H W; van der Burg S H; Drijfhout J W; Kenemans P; van de Velde C J; Brand A; Momburg F; Kast W M; Melief C J
In vitro induction of human cytotoxic T lymphocyte responses against peptides of mutant and wild-type p53.
European journal of immunology 1993;23(9):2072-7.
1993: Vlasveld L T; Hekman A; Vyth-Dreese F A; Rankin E M; Scharenberg J G; Voordouw A C; Sein J J; Dellemijn T A; Rodenhuis S; Melief C J
A phase I study of prolonged continuous infusion of low dose recombinant interleukin-2 in melanoma and renal cell cancer. Part II: Immunological aspects.
British journal of cancer 1993;68(3):559-67.
1993: Feltkamp M C; Smits H L; Vierboom M P; Minnaar R P; de Jongh B M; Drijfhout J W; ter Schegget J; Melief C J; Kast W M
Vaccination with cytotoxic T lymphocyte epitope-containing peptide protects against a tumor induced by human papillomavirus type 16-transformed cells.
European journal of immunology 1993;23(9):2242-9.
1993: Nijman H W; Houbiers J G; van der Burg S H; Vierboom M P; Kenemans P; Kast W M; Melief C J
Characterization of cytotoxic T lymphocyte epitopes of a self-protein, p53, and a non-self-protein, influenza matrix: relationship between major histocompatibility complex peptide binding affinity and immune responsiveness to peptides.
Journal of immunotherapy with emphasis on tumor immunology : official journal of the Society for Biological Therapy 1993;14(2):121-6.
1993: Kast W M; Brandt R M; Drijfhout J W; Melief C J
Human leukocyte antigen-A2.1 restricted candidate cytotoxic T lymphocyte epitopes of human papillomavirus type 16 E6 and E7 proteins identified by using the processing-defective human cell line T2.
Journal of immunotherapy with emphasis on tumor immunology : official journal of the Society for Biological Therapy 1993;14(2):115-20.
1993: Toes R E; den Haan J M; Feltkamp M C; Blom R J; Melief C J; Claassen E; Kast W M
In vivo detection of fluorescent tumor-specific cytotoxic T cell clones.
Journal of immunological methods 1993;163(1):23-32.
1993: Melief C J
Prospects of T-cell immunotherapy for cancer by peptide vaccination.
Seminars in hematology 1993;30(3 Suppl 3):32-3.
1993: van de Wiel-van Kemenade E; Ligtenberg M J; de Boer A J; Buijs F; Vos H L; Melief C J; Hilkens J; Figdor C G
Episialin (MUC1) inhibits cytotoxic lymphocyte-target cell interaction.
Journal of immunology (Baltimore, Md. : 1950) 1993;151(2):767-76.
1993: Mulder A; Kardol M; Blom J; Jolley W B; Melief C J; Bruning H
A human monoclonal antibody, produced following in vitro immunization, recognizing an epitope shared by HLA-A2 subtypes and HLA-A28.
Tissue antigens 1993;42(1):27-34.
1993: Nijman H W; Houbiers J G; Vierboom M P; van der Burg S H; Drijfhout J W; D'Amaro J; Kenemans P; Melief C J; Kast W M
Identification of peptide sequences that potentially trigger HLA-A2.1-restricted cytotoxic T lymphocytes.
European journal of immunology 1993;23(6):1215-9.
1993: Mulder A; Kardol M; Blom J; Jolley W B; Melief C J; Bruning J W
Characterization of two human monoclonal antibodies reactive with HLA-B12 and HLA-B60, respectively, raised by in vitro secondary immunization of peripheral blood lymphocytes.
Human immunology 1993;36(3):186-92.
1993: Vyth-Dreese F A; Van Kooyk Y; Dellemijn T A; Melief C J; Figdor C G
Regulatory effect of interleukin-4 (IL-4) on the expression and function of lymphocyte adhesion receptors involved in IL-2-induced cell aggregation.
Immunology 1993;78(2):244-51.
1993: Vuist W M; Visseren M J; Otsen M; Bos K; Vyth-Dreese F A; Figdor C G; Melief C J; Hekman A
Enhancement of the antibody-dependent cellular cytotoxicity of human peripheral blood lymphocytes with interleukin-2 and interferon alpha.
Cancer immunology, immunotherapy : CII 1993;36(3):163-70.
1993: Ossevoort M A; Toes R E; De Bruijn M L; Melief C J; Figdor C G; Kast W M
The MHC expression of dendritic cells from mouse spleen isolated by centrifugal elutriation is upregulated during short term culture.
Advances in experimental medicine and biology 1993;329():185-9.
1993: Vlasveld L T; Beijnen J H; Sein J J; Rankin E M; Melief C J; Hekman A
Reconstitution of recombinant interleukin-2 (rIL-2): a comparative study of various rIL-2 muteins.
European journal of cancer (Oxford, England : 1990) 1993;29A(14):1977-9.
1992: Loenen W A; Gravestein L A; Beumer S; Melief C J; Hagemeijer A; Borst J
Genomic organization and chromosomal localization of the human CD27 gene.
Journal of immunology (Baltimore, Md. : 1950) 1992;149(12):3937-43.
1992: De Bruijn M L; Nieland J D; Schumacher T N; Ploegh H L; Kast W M; Melief C J
Mechanisms of induction of primary virus-specific cytotoxic T lymphocyte responses.
European journal of immunology 1992;22(11):3013-20.
1992: Ossevoort M A; Toes R E; De Bruijn M L; Melief C J; Figdor C G; Kast W M
A rapid isolation procedure for dendritic cells from mouse spleen by centrifugal elutriation.
Journal of immunological methods 1992;155(1):101-11.
1992: De Bruijn M L; Nieland J D; Harding C V; Melief C J
Processing and presentation of intact hen egg-white lysozyme by dendritic cells.
European journal of immunology 1992;22(9):2347-52.
1992: Sijts A J; De Bruijn M L; Nieland J D; Kast W M; Melief C J
Cytotoxic T lymphocytes against the antigen-processing-defective RMA-S tumor cell line.
European journal of immunology 1992;22(6):1639-42.
1992: Van de Wiel-van Kemenade E; Te Velde A A; De Boer A J; Weening R S; Fischer A; Borst J; Melief C J; Figdor C G
Both LFA-1-positive and -deficient T cell clones require the CD2/LFA-3 interaction for specific cytolytic activation.
European journal of immunology 1992;22(6):1467-75.
1992: Vlasveld L T; Rankin E M; Hekman A; Rodenhuis S; Beijnen J H; Hilton A M; Dubbelman A C; Vyth-Dreese F A; Melief C J
A phase I study of prolonged continuous infusion of low dose recombinant interleukin-2 in melanoma and renal cell cancer. Part I: Clinical aspects.
British journal of cancer 1992;65(5):744-50.
1992: van Oostveen J W; Breit T M; de Wolf J T; Brandt R M; Smit J W; van Dongen J J; Borst J; Melief C J
Polyclonal expansion of T-cell receptor-gamma delta+ T lymphocytes associated with neutropenia and thrombocytopenia.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1992;6(5):410-8.
1992: van de Wiel-van Kemenade E; van Kooyk Y; de Boer A J; Huijbens R J; Weder P; van de Kasteele W; Melief C J; Figdor C G
Adhesion of T and B lymphocytes to extracellular matrix and endothelial cells can be regulated through the beta subunit of VLA.
The Journal of cell biology 1992;117(2):461-70.
1992: Vennegoor C J; van de Wiel-van Kemenade E; Huijbens R J; Sanchez-Madrid F; Melief C J; Figdor C G
Role of LFA-1 and VLA-4 in the adhesion of cloned normal and LFA-1 (CD11/CD18)-deficient T cells to cultured endothelial cells. Indication for a new adhesion pathway.
Journal of immunology (Baltimore, Md. : 1950) 1992;148(4):1093-101.
1992: Rozendaal L; Pals S T; Melief C J; Gleichmann E
Protection from lethal graft-vs.-host disease by donor stem cell repopulation.
European journal of immunology 1992;22(2):575-9.
1992: Melief C J
Tumor eradication by adoptive transfer of cytotoxic T lymphocytes.
Advances in cancer research 1992;58():143-75.
1992: Melief C J; Kast W M
Lessons from T cell responses to virus induced tumours for cancer eradication in general.
Cancer surveys 1992;13():81-99.
1991: De Bruijn M L; Schumacher T N; Nieland J D; Ploegh H L; Kast W M; Melief C J
Peptide loading of empty major histocompatibility complex molecules on RMA-S cells allows the induction of primary cytotoxic T lymphocyte responses.
European journal of immunology 1991;21(12):2963-70.
1991: van Twuyver E; Mooijaart R J; ten Berge I J; van der Horst A R; Wilmink J M; Kast W M; Melief C J; de Waal L P
Pretransplantation blood transfusion revisited.
The New England journal of medicine 1991;325(17):1210-3.
1991: Melief C J; Kast W M
Cytotoxic T lymphocyte therapy of cancer and tumor escape mechanisms.
Seminars in cancer biology 1991;2(5):347-54.
1991: Kast W M; Melief C J
In vivo efficacy of virus-derived peptides and virus-specific cytotoxic T lymphocytes.
Immunology letters 1991;30(2):229-32.
1991: Melief C J; Kast W M
T-cell immunotherapy of cancer.
Research in immunology 1991;142(5-6):425-9.
1991: Schumacher T N; De Bruijn M L; Vernie L N; Kast W M; Melief C J; Neefjes J J; Ploegh H L
Peptide selection by MHC class I molecules.
Nature 1991;350(6320):703-6.
1991: Kast W M; Roux L; Curren J; Blom H J; Voordouw A C; Meloen R H; Kolakofsky D; Melief C J
Protection against lethal Sendai virus infection by in vivo priming of virus-specific cytotoxic T lymphocytes with a free synthetic peptide.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(6):2283-7.
1991: de Waal L P; van Twuyver E; Mooijaart R J; Lardy N M; Kast W M; Melief C J
Mechanisms of transplantation tolerance: do anti-idiotypic antibodies play a role?
Transplantation proceedings 1991;23(1 Pt 1):155-6.
1991: Kast W M; Melief C J
Fine peptide specificity of cytotoxic T lymphocytes directed against adenovirus-induced tumours and peptide-MHC binding.
International journal of cancer. Supplement = Journal international du cancer. Supplement 1991;6():90-4.
1991: van Oostveen J W; Ploem J E; Brandt R M; Melief C J
Remission of monoclonal chronic T-cell expansion associated with severe anemia.
Leukemia research 1991;15(12):1167-74.
1991: Hekman A; Honselaar A; Vuist W M; Sein J J; Rodenhuis S; ten Bokkel Huinink W W; Somers R; Rümke P; Melief C J
Initial experience with treatment of human B cell lymphoma with anti-CD19 monoclonal antibody.
Cancer immunology, immunotherapy : CII 1991;32(6):364-72.
1990: Rozendaal L; Pals S T; Gleichmann E; Melief C J
Persistence of allospecific helper T cells is required for maintaining autoantibody formation in lupus-like graft-versus-host disease.
Clinical and experimental immunology 1990;82(3):527-32.
1990: van Twuyver E; Mooijaart R J; Kast W M; Melief C J; de Waal L P
Different requirements for the regulation of transplantation tolerance induction for allogeneic versus xenogeneic major histocompatibility complex antigens.
Human immunology 1990;29(3):220-8.
1990: Kast W M; Bluestone J A; Heemskerk M H; Spaargaren J; Voordouw A C; Ellenhorn J D; Melief C J
Treatment with monoclonal anti-CD3 antibody protects against lethal Sendai virus infection by induction of natural killer cells.
Journal of immunology (Baltimore, Md. : 1950) 1990;145(7):2254-9.
1990: Vuist W M; van Buitenen F; Hekman A; Melief C J
Two distinct mechanisms of antitumor activity mediated by the combination of interleukin 2 and monoclonal antibodies.
Cancer research 1990;50(18):5767-72.
1990: Schumacher T N; Heemels M T; Neefjes J J; Kast W M; Melief C J; Ploegh H L
Direct binding of peptide to empty MHC class I molecules on intact cells and in vitro.
Cell 1990;62(3):563-7.
1990: Melief C J; Kast W M
Efficacy of cytotoxic T lymphocytes against virus-induced tumors.
Cancer cells (Cold Spring Harbor, N.Y. : 1989) 1990;2(4):116-20.
1990: van Twuyver E; Kast W M; Mooijaart R J; Melief C J; De Waal L P
Induction of transplantation tolerance by intravenous injection of allogeneic lymphocytes across an H-2 class II mismatch. Different mechanisms operate in tolerization across an H-2 class I vs. H-2 class II disparity.
European journal of immunology 1990;20(2):441-4.
1990: Neefjes J J; De Bruijn M L; Boog C J; Nieland J D; Boes J; Melief C J; Ploegh H L
N-linked glycan modification on antigen-presenting cells restores an allospecific cytotoxic T cell response.
The Journal of experimental medicine 1990;171(2):583-8.
1989: van Twuyver E; Kast W M; Mooijaart R J; Wilmink J M; Melief C J; de Waal L P
Allograft tolerance induction in adult mice associated with functional deletion of specific CTL precursors.
Transplantation 1989;48(5):844-7.
1989: Kast W M; Offringa R; Peters P J; Voordouw A C; Meloen R H; van der Eb A J; Melief C J
Eradication of adenovirus E1-induced tumors by E1A-specific cytotoxic T lymphocytes.
Cell 1989;59(4):603-14.
1989: Melief C J
Dendritic cells as specialized antigen-presenting cells.
Research in immunology 1989;140(9):902-6; discussion 918-26.
1989: Krimpenfort P; Ossendorp F; Borst J; Melief C; Berns A
T cell depletion in transgenic mice carrying a mutant gene for TCR-beta.
Nature 1989;341(6244):742-6.
1989: Rozendaal L; Pals S T; Schilham M; Melief C J; Gleichmann E
Allosuppression of B cells in vitro by graft-vs.-host reaction-derived T cells is caused by cytotoxic T lymphocytes.
European journal of immunology 1989;19(9):1669-75.
1989: Vyth-Dreese F A; Hekman A; Wijffels J; Geertsma M; Dellemijn T A; Dosda J; Melief C J; Bertoglio J
Functional and molecular characterization of B cell line derived interleukin-1 alpha.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1989;3(8):585-92.
1989: Vuist W M; v Buitenen F; de Rie M A; Hekman A; Rümke P; Melief C J
Potentiation by interleukin 2 of Burkitt's lymphoma therapy with anti-pan B (anti-CD19) monoclonal antibodies in a mouse xenotransplantation model.
Cancer research 1989;49(14):3783-8.
1989: Matthews E A; Vasmel W L; Schoenmakers H J; Melief C J
Retrovirally induced murine B-cell tumors rarely show proviral integration in sites common in T-cell tumors.
International journal of cancer. Journal international du cancer 1989;43(6):1120-5.
1989: Vasmel W L; Matthews E A; Gillis C P; Nieland J; Borst E A; Leupers C J; Melief C J; Slater R M
Distinct chromosomal abnormalities in murine leukemia virus-induced T- and B-cell lymphomas.
International journal of cancer. Journal international du cancer 1989;43(6):1112-9.
1989: Stam N J; Kast W M; Voordouw A C; Pastoors L B; van der Hoeven F A; Melief C J; Ploegh H L
Lack of correlation between levels of MHC class I antigen and susceptibility to lysis of small cellular lung carcinoma (SCLC) by natural killer cells.
Journal of immunology (Baltimore, Md. : 1950) 1989;142(11):4113-7.
1989: Vasmel W L; Sijts E J; Leupers C J; Matthews E A; Melief C J
Primary virus-induced lymphomas evade T cell immunity by failure to express viral antigens.
The Journal of experimental medicine 1989;169(4):1233-54.
1989: Boog C J; Neefjes J J; Boes J; Ploegh H L; Melief C J
Specific immune responses restored by alteration in carbohydrate chains of surface molecules on antigen-presenting cells.
European journal of immunology 1989;19(3):537-42.
1989: van Twuyver E; Kast W M; Mooijaart R J; Melief C J; de Waal L P
Transfusion-induced skin allograft enhancement across an H-2 class-I mismatch is caused by a clonal deletion of donor-specific cytotoxic T-lymphocyte precursors within the allograft.
Transplantation proceedings 1989;21(1 Pt 1):1169-70.
1989: Borst J; Sluyser C; De Vries E; Klein H; Melief C J; Van Lier R A
Alternative molecular form of human T cell-specific antigen CD27 expressed upon T cell activation.
European journal of immunology 1989;19(2):357-64.
1989: Melief C J; Vasmel W L; Offringa R; Sijts E J; Matthews E A; Peters P J; Meloen R H; van der Eb A J; Kast W M
Immunosurveillance of virus-induced tumors.
Cold Spring Harbor symposia on quantitative biology 1989;54 Pt 1():597-603.
1988: Kast W M; Van Twuyver E; Mooijaart R J; Verveld M; Kamphuis A G; Melief C J; De Waal L P
Mechanism of skin allograft enhancement across an H-2 class I mutant difference. Evidence for involvement of veto cells.
European journal of immunology 1988;18(12):2105-8.
1988: Van Seventer G A; Van Lier R A; Kuijpers K C; Spits H; Melief C J
Regulatory role of the CD8 antigen in both CD3 and CD2 monoclonal antibody-induced nonspecific cytotoxicity of class I- and class II-allospecific cytotoxic T cell clones.
European journal of immunology 1988;18(12):1973-8.
1988: Vasmel W L; Zijlstra M; Radaszkiewicz T; Leupers C J; de Goede R E; Melief C J
Major histocompatibility complex class II-regulated immunity to murine leukemia virus protects against early T- but not late B-cell lymphomas.
Journal of virology 1988;62(9):3156-66.
1988: van Seventer G A; Spits H; Yssel H; Melief C J; Ivanyi P
Differential recognition by human cytotoxic T cell clones of human M1 fibroblasts transfected with an HLA-B7 gene (JY150) suggests the existence of two different HLA-B7 alleles in the cell line JY (HLA-A2,2;B7,7;Cw-,-;DR4,w6).
Journal of immunology (Baltimore, Md. : 1950) 1988;141(2):417-22.
1988: Van Lier R A; Pool M O; Kabel P; Mous S; Terpstra F; De Rie M A; Melief C J; Miedema F
Anti-CD27 monoclonal antibodies identify two functionally distinct subpopulations within the CD4+ T cell subset.
European journal of immunology 1988;18(5):811-6.
1988: Kast W M; Boog C J; Roep B O; Voordouw A C; Melief C J
Failure or success in the restoration of virus-specific cytotoxic T lymphocyte response defects by dendritic cells.
Journal of immunology (Baltimore, Md. : 1950) 1988;140(9):3186-93.
1988: Boog C J; Boes J; Melief C J
Role of dendritic cells in the regulation of class I restricted cytotoxic T lymphocyte responses.
Journal of immunology (Baltimore, Md. : 1950) 1988;140(10):3331-7.
1988: Vyth-Dreese F A; Dellemijn T A; Hekman A; Melief C J
Idiotypic immunoglobulin secretion by human B cell non-Hodgkin's lymphomas is related to the expression of the interleukin-2 receptor.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1988;2(4):231-5.
1988: Boog C J; Boes J; Melief C J
Stimulation with dendritic cells decreases or obviates the CD4+ helper cell requirement in cytotoxic T lymphocyte responses.
European journal of immunology 1988;18(2):219-23.
1988: de Rie M A; van Heemstra D J; Huijgens P C; Zeijlemaker W P; Out T A; Melief C J; von dem Borne A E
Production of mouse monoclonal antibodies for the analysis of idiotypes in serum of patients with chronic lymphatic leukaemia.
British journal of haematology 1988;68(1):11-6.
1988: Melief C J; Boog C J; Vasmel W L; Boes J; Voordouw A C; Kast W M
Dendritic cells and antigen presentation in the regulation of cytotoxic T lymphocyte responses against viruses and transplantation antigens.
Annals of the New York Academy of Sciences 1988;532():280-91.
1987: van Seventer G A; Kuijpers K C; van Lier R A; de Groot E R; Aarden L A; Melief C J
Mechanism of inhibition and induction of cytolytic activity in cytotoxic T lymphocytes by CD3 monoclonal antibodies.
Journal of immunology (Baltimore, Md. : 1950) 1987;139(8):2545-50.
1987: Vasmel W L; Radaszkiewicz T; Miltenburg A M; Zijlstra M; Melief C J
Refinement and precision in the classification of murine lymphomas by genotyping with immunoglobulin and T cell receptor probes.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1987;1(3):155-62.
1986: Van Seventer G A; Van Lier R A; Spits H; Ivanyi P; Melief C J
Evidence for a regulatory role of the T8 (CD8) antigen in antigen-specific and anti-T3-(CD3)-induced lytic activity of allospecific cytotoxic T lymphocyte clones.
European journal of immunology 1986;16(11):1363-71.
1986: Cuypers H T; Selten G C; Zijlstra M; de Goede R E; Melief C J; Berns A J
Tumor progression in murine leukemia virus-induced T-cell lymphomas: monitoring clonal selections with viral and cellular probes.
Journal of virology 1986;60(1):230-41.
1986: Zijlstra M; Vasmel W L; Voormanns M; de Goede R E; Schoenmakers H J; Nieland J; Slater R M; Melief C J
Imbalanced MHC class II molecule expression at surface of murine B cell lymphomas.
The Journal of experimental medicine 1986;163(5):1213-26.
1986: Zijlstra M; Vasmel W L; Radaskiewicz T; Matthews E; Melief C J
The H-2 complex regulates both the susceptibility to mouse viral lymphomagenesis and the phenotype of the virus-induced lymphomas.
Journal of immunogenetics 1986;13(2-3):69-76.
1986: Zijlstra M; Quint W; Cuypers T; Radaszkiewicz T; Schoenmakers H; de Goede R; Melief C
Ecotropic and mink cell focus-forming murine leukemia viruses integrate in mouse T, B, and non-T/non-B cell lymphoma DNA.
Journal of virology 1986;57(3):1037-47.
1986: Pals S T; Zijstra M; Radaszkiewicz T; Quint W; Cuypers H T; Schoenmakers H J; Melief C J; Berns A; Gleichmann E
Immunologic induction of malignant lymphoma: graft-vs-host reaction-induced B cell lymphomas contain integrations of predominantly ecotropic murine leukemia proviruses.
Journal of immunology (Baltimore, Md. : 1950) 1986;136(1):331-9.
1986: Zijlstra M; Schoenmakers H J; Melief C J
Differences in oncogenicity among murine leukemia virus isolates are not correlated with the magnitude of H-2 regulated anti-viral envelope antibody responses.
Leukemia research 1986;10(9):1121-9.
1986: Goudsmit J; Miedema F; Breederveld C; Terpstra F; Roos M; Schellekens P; Melief C
Antibodies to the human T-cell lymphoma/leukemia virus type I in Dutch haemophiliacs.
Vox sanguinis 1986;50(1):12-5.
1985: Boog C J; Kast W M; Timmers H T; Boes J; de Waal L P; Melief C J
Abolition of specific immune response defect by immunization with dendritic cells.
Nature 1985;318(6041):59-62.
1985: Boog C J; de Waal L P; Timmers H T; Boes J; Melief C J
H-2 class I mutants utilize novel restriction specificities in the trinitrophenyl-specific cytotoxic T-lymphocyte response.
Cellular immunology 1985;95(2):420-7.
1985: Miedema F; Terpstra F G; Smit J W; van der Veen J P; Melief C J
T gamma lymphocytosis is clinically non-progressive but immunologically heterogeneous.
Clinical and experimental immunology 1985;61(2):440-9.
1985: Miedema F; Tetteroo P A; Terpstra F G; Keizer G; Roos M; Weening R S; Weemaes C M; Roos D; Melief C J
Immunologic studies with LFA-1- and Mo1-deficient lymphocytes from a patient with recurrent bacterial infections.
Journal of immunology (Baltimore, Md. : 1950) 1985;134(5):3075-81.
1984: Selten G; Cuypers H T; Zijlstra M; Melief C; Berns A
Involvement of c-myc in MuLV-induced T cell lymphomas in mice: frequency and mechanisms of activation.
The EMBO journal 1984;3(13):3215-22.
1984: Zijlstra M; de Goede R E; Schoenmakers H; Radaszkiewicz T; Melief C J
Ecotropic and dualtropic mink cell focus-inducing murine leukemia viruses can induce a wide spectrum of H-2 controlled lymphoma types.
Virology 1984;138(2):198-211.
1984: Cuypers H T; Selten G; Quint W; Zijlstra M; Maandag E R; Boelens W; van Wezenbeek P; Melief C; Berns A
Murine leukemia virus-induced T-cell lymphomagenesis: integration of proviruses in a distinct chromosomal region.
Cell 1984;37(1):141-50.
1984: Miedema F; Terpstra F G; Smit J W; Daenen S; Gerrits W; Hegde U; Matutes E; Catovsky D; Greaves M F; Melief C J
Functional properties of neoplastic T cells in adult T cell lymphoma/leukemia patients from the Caribbean.
Blood 1984;63(2):477-81.
1983: van de Griend R J; van der Reijden H J; Bolhuis R L; Melief C J; von dem Borne A E; Roos D
Enzyme analysis of lymphoproliferative diseases: a useful addition to cell surface phenotyping.
Blood 1983;62(3):669-76.
1983: Vlug A; Zijlstra M; de Goede R E; Hesselink W G; Schoenmakers H J; Melief C J
H-2 control of the cytotoxic antibody response against a newly defined MuLV-related cell-surface antigen: G(B10.A).
International journal of cancer. Journal international du cancer 1983;31(5):617-26.
1983: Zijlstra M; de Goede R E; Schoenmakers H J; Schinkel A H; Hesselink W G; Portis J L; Melief C J
Naturally occurring leukemia viruses in H-2 congenic C57BL mice. III. Characterization of C-type viruses isolated from lymphomas induced by milk transmission of B-ecotropic virus.
Virology 1983;125(1):47-63.
1982: van der Reijden H J; van der Gaag R; Pinkster J; Rümke H C; van't Veer M B; Melief C J; von dem Borne A E
Chronic lymphocytic leukemia. Immunologic markers and functional properties of the leukemic cells.
Cancer 1982;50(12):2826-33.
1982: Rümke H C; Miedema F; ten Berge I J; Terpstra F; van der Reijden H J; van de Griend R J; de Bruin H G; von dem Borne A E; Smit J W; Zeijlemaker W P; Melief C J
Functional properties of T cells in patients with chronic T gamma lymphocytosis and chronic T cell neoplasia.
Journal of immunology (Baltimore, Md. : 1950) 1982;129(1):419-26.
1982: van de Griend R J; ten Berge I; Tanke H J; Roos D; Schellekens P T; Melief C J; Zeijlemaker W P; Astaldi A
Characterization of two subsets of human T gamma cells.
Journal of immunology (Baltimore, Md. : 1950) 1982;128(5):1979-85.
1982: Thien S L; Catovsky D; Oscier D; Goldman J M; van der Reijden H J; Melief C J; Rümke H C; Ten Berge R J; von dem Borne A E
T-chronic lymphocytic leukaemia presenting as primary hypogammaglobulinaemia--evidence of a proliferation of T-suppressor cells.
Clinical and experimental immunology 1982;47(3):670-6.
1981: Vlug A; Schoenmakers H J; Melief C J
Genes of the H-2 complex regulate the antibody response to murine leukemia virus.
Journal of immunology (Baltimore, Md. : 1950) 1981;126(6):2355-60.
1980: Vlug A; Melief C J; de Bruyne C; Schoenmakers H; Molenaar J L
Naturally occurring leukemia viruses in H-2 congenic C57BL mice. II. Antibody response to viral envelope antigens.
Journal of the National Cancer Institute 1980;64(5):1191-8.
1980: Melief C J; Vlug A; de Goede R E; de Bruyne C; Barendsen W; de Greeve P
Naturally occurring leukemia viruses in H-2 congenic C57BL mice. I. High lymphoma incidence following milk-borne transmission of virus.
Journal of the National Cancer Institute 1980;64(5):1179-89.

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