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Gerry Melino
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47
Candi, Eleonora
36
Terrinoni, Alessandro
34
Bernassola, Francesca
32
Knight, Richard
26
Piacentini, Mauro
25
de Laurenzi, Vincenzo
23
Ranalli, Marco
20
Catani, Maria Valeria
17
Annicchiarico-Petruzzelli, M
13
Corazzari, Marco
12
Guerrieri, Piero
11
Redfern, Christopher
11
Lovat, Penny
11
sayan, emre
11
Maccarrone, Mauro
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All Publications
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2009: Menghini Rossella; Casagrande Viviana; Cardellini Marina; Martelli Eugenio; Terrinoni Alessandro; Amati Francesca; Vasa-Nicotera Mariuca; Ippoliti Arnaldo; Novelli Giuseppe; Melino Gerry; Lauro Renato; Federici Massimo
MicroRNA 217 modulates endothelial cell senescence via silent information regulator 1.
Circulation 2009;120(15):1524-32.
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2009: Gonfloni Stefania; Di Tella Lucia; Caldarola Sara; Cannata Stefano M; Klinger Francesca G; Di Bartolomeo Claudia; Mattei Maurizio; Candi Eleonora; De Felici Massimo; Melino Gerry; Cesareni Gianni
Inhibition of the c-Abl-TAp63 pathway protects mouse oocytes from chemotherapy-induced death.
Nature medicine 2009;15(10):1179-85.
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2009: Klanrit P; Taebunpakul P; Flinterman M B; Odell E W; Riaz M A; Melino G; Salomoni P; Mymryk J S; Gäken J; Farzaneh F; Tavassoli M
PML involvement in the p73-mediated E1A-induced suppression of EGFR and induction of apoptosis in head and neck cancers.
Oncogene 2009;28(39):3499-512.
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2009: Rossi Mario; Munarriz Eliana Rosa; Bartesaghi Stefano; Milanese Marco; Dinsdale David; Guerra-Martin Maria Azucena; Bampton Edward T W; Glynn Paul; Bonanno Giambattista; Knight Richard A; Nicotera Pierluigi; Melino Gerry
Desmethylclomipramine induces the accumulation of autophagy markers by blocking autophagic flux.
Journal of cell science 2009;122(Pt 18):3330-9.
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2009: Tóth Beáta; Sarang Zsolt; Vereb György; Zhang Ailiang; Tanaka Sakae; Melino Gerry; Fésüs László; Szondy Zsuzsa
Over-expression of integrin beta3 can partially overcome the defect of integrin beta3 signaling in transglutaminase 2 null macrophages.
Immunology letters 2009;126(1-2):22-8.
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2009: Peschiaroli A; Scialpi F; Bernassola F; Pagano M; Melino G
The F-box protein FBXO45 promotes the proteasome-dependent degradation of p73.
Oncogene 2009;28(35):3157-66.
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2009: Inoue S; Browne G; Melino G; Cohen G M
Ordering of caspases in cells undergoing apoptosis by the intrinsic pathway.
Cell death and differentiation 2009;16(7):1053-61.
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2009: Tarantino U; Oliva F; Taurisano G; Orlandi A; Pietroni V; Candi E; Melino G; Maffulli N
FXIIIA and TGF-beta over-expression produces normal musculo-skeletal phenotype in TG2-/- mice.
Amino acids 2009;36(4):679-84.
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2009: Orlandi A; Oliva F; Taurisano G; Candi E; Di Lascio A; Melino G; Spagnoli L G; Tarantino U
Transglutaminase-2 differently regulates cartilage destruction and osteophyte formation in a surgical model of osteoarthritis.
Amino acids 2009;36(4):755-63.
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2009: Codispoti Andrea; Colombo Enrico; Zocchi Loredana; Serra Valeria; Pertusi Ginevra; Leigheb Giorgio; Tiberio Rossana; Bornacina Guido; Zuccoli Riccardo; Ramponi Antonio; Campione Elena; Melino Gerry; Terrinoni Alessandro
Knuckle pads, in an epidermal palmoplantar keratoderma patient with Keratin 9 R163W transgrediens expression.
European journal of dermatology : EJD 2009;19(2):114-8.
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2009: Tóth Beáta; Garabuczi Eva; Sarang Zsolt; Vereb György; Vámosi György; Aeschlimann Daniel; Blaskó Bernadett; Bécsi Bálint; Erdõdi Ferenc; Lacy-Hulbert Adam; Zhang Ailiang; Falasca Laura; Birge Raymond B; Balajthy Zoltán; Melino Gerry; Fésüs László; Szondy Zsuzsa
Transglutaminase 2 is needed for the formation of an efficient phagocyte portal in macrophages engulfing apoptotic cells.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(4):2084-92.
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2009: Vernole Patrizia; Neale Michael H; Barcaroli Daniela; Munarriz Eliana; Knight Richard A; Tomasini Richard; Mak Tak W; Melino Gerry; De Laurenzi Vincenzo
TAp73alpha binds the kinetochore proteins Bub1 and Bub3 resulting in polyploidy.
Cell cycle (Georgetown, Tex.) 2009;8(3):421-9.
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2009: Oliva Francesco; Zocchi Loredana; Codispoti Andrea; Candi Eleonora; Celi Monica; Melino Gerry; Maffulli Nicola; Tarantino Umberto
Transglutaminases expression in human supraspinatus tendon ruptures and in mouse tendons.
Biochemical and biophysical research communications 2009;379(4):887-91.
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2009: Rossi Mario; Inoue Satoshi; Walewska Renata; Knight Richard A; Dyer Martin J S; Cohen Gerald M; Melino Gerry
Caspase cleavage of Itch in chronic lymphocytic leukemia cells.
Biochemical and biophysical research communications 2009;379(3):659-64.
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2009: Borrelli S; Candi E; Alotto D; Castagnoli C; Melino G; Viganò M A; Mantovani R
p63 regulates the caspase-8-FLIP apoptotic pathway in epidermis.
Cell death and differentiation 2009;16(2):253-63.
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2009: Tomasini Richard; Tsuchihara Katsuya; Tsuda Chiharu; Lau Suzanne K; Wilhelm Margareta; Ruffini Alessandro; Tsao Ming-sound; Iovanna Juan L; Jurisicova Andrea; Melino Gerry; Mak Tak W
TAp73 regulates the spindle assembly checkpoint by modulating BubR1 activity.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(3):797-802.
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2008: Aberdam Daniel; Candi Eleonora; Knight Richard A; Melino Gerry
miRNAs, 'stemness' and skin.
Trends in biochemical sciences 2008;33(12):583-91.
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2008: Raimondo Domenico; Giorgetti Alejandro; Bernassola Francesca; Melino Gerry; Tramontano Anna
Modelling and molecular dynamics of the interaction between the E3 ubiquitin ligase Itch and the E2 UbcH7.
Biochemical pharmacology 2008;76(11):1620-7.
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2008: Scialpi Flavia; Malatesta Martina; Peschiaroli Angelo; Rossi Mario; Melino Gerry; Bernassola Francesca
Itch self-polyubiquitylation occurs through lysine-63 linkages.
Biochemical pharmacology 2008;76(11):1515-21.
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2008: Pietroni Valentina; Di Giorgi Sabrina; Paradisi Andrea; Ahvazi Bijan; Candi Eleonora; Melino Gerry
Inactive and highly active, proteolytically processed transglutaminase-5 in epithelial cells.
The Journal of investigative dermatology 2008;128(12):2760-6.
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2008: Bernardini Sergio; Gravina Paolo; Croce Nicoletta; Perricone Roberto; Knight Richard A; Valentini Alessandra; Melino Gerry; Federici Giorgio
Itch gene polymorphisms in healthy population and in patients affected by rheumatoid arthritis and atopic dermatitis.
Cell cycle (Georgetown, Tex.) 2008;7(22):3607-9.
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2008: Roperch Jean-Pierre; El Ouadrani Karima; Hendrix Ann; Emami Shahin; De Wever Olivier; Melino Gerry; Gespach Christian
Netrin-1 induces apoptosis in human cervical tumor cells via the TAp73alpha tumor suppressor.
Cancer research 2008;68(20):8231-9.
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2008: Tomasini Richard; Tsuchihara Katsuya; Wilhelm Margareta; Fujitani Masashi; Rufini Alessandro; Cheung Carol C; Khan Fatima; Itie-Youten Annick; Wakeham Andrew; Tsao Ming-Sound; Iovanna Juan L; Squire Jeremy; Jurisica Igor; Kaplan David; Melino Gerry; Jurisicova Andrea; Mak Tak W
TAp73 knockout shows genomic instability with infertility and tumor suppressor functions.
Genes & development 2008;22(19):2677-91.
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2008: Shweke Nasim; Boulos Nada; Jouanneau Chantal; Vandermeersch Sophie; Melino Gerry; Dussaule Jean-Claude; Chatziantoniou Christos; Ronco Pierre; Boffa Jean-Jacques
Tissue transglutaminase contributes to interstitial renal fibrosis by favoring accumulation of fibrillar collagen through TGF-beta activation and cell infiltration.
The American journal of pathology 2008;173(3):631-42.
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2008: Bongiorno-Borbone Lucilla; De Cola Antonella; Vernole Patrizia; Finos Livio; Barcaroli Daniela; Knight Richard A; Melino Gerry; De Laurenzi Vincenzo
FLASH and NPAT positive but not Coilin positive Cajal Bodies correlate with cell ploidy.
Cell cycle (Georgetown, Tex.) 2008;7(15):2357-67.
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2008: Bernassola Francesca; Karin Michael; Ciechanover Aaron; Melino Gerry
The HECT family of E3 ubiquitin ligases: multiple players in cancer development.
Cancer cell 2008;14(1):10-21.
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2008: Melino G; Gallagher E; Aqeilan R I; Knight R; Peschiaroli A; Rossi M; Scialpi F; Malatesta M; Zocchi L; Browne G; Ciechanover A; Bernassola F
Itch: a HECT-type E3 ligase regulating immunity, skin and cancer.
Cell death and differentiation 2008;15(7):1103-12.
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2008: Sayan A E; Sayan B S; Gogvadze V; Dinsdale D; Nyman U; Hansen T M; Zhivotovsky B; Cohen G M; Knight R A; Melino G
P73 and caspase-cleaved p73 fragments localize to mitochondria and augment TRAIL-induced apoptosis.
Oncogene 2008;27(31):4363-72.
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2008: Shin Dong-Myung; Jeon Ju-Hong; Kim Chai-Wan; Cho Sung-Yup; Lee Hye-Jin; Jang Gi-Yong; Jeong Eui Man; Lee Dong-Sup; Kang Ja-Heon; Melino Gerry; Park Sang-Chul; Kim In-Gyu
TGFbeta mediates activation of transglutaminase 2 in response to oxidative stress that leads to protein aggregation.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2008;22(7):2498-507.
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2008: Soond Surinder M; Barry Sean P; Melino Gerry; Knight Richard A; Latchman David S; Stephanou Anastasis
p73-mediated transcriptional activity is negatively regulated by polo-like kinase 1.
Cell cycle (Georgetown, Tex.) 2008;7(9):1214-23.
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2008: Tomasini Richard; Mak Tak W; Melino Gerry
The impact of p53 and p73 on aneuploidy and cancer.
Trends in cell biology 2008;18(5):244-52.
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2008: Sundvall Maria; Korhonen Anna; Paatero Ilkka; Gaudio Eugenio; Melino Gerry; Croce Carlo M; Aqeilan Rami I; Elenius Klaus
Isoform-specific monoubiquitination, endocytosis, and degradation of alternatively spliced ErbB4 isoforms.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(11):4162-7.
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2008: Zocchi Loredana; Bourdon Jean Christophe; Codispoti Andrea; Knight Richard; Lane David P; Melino Gerry; Terrinoni Alessandro
Scotin: A new p63 target gene expressed during epidermal differentiation.
Biochemical and biophysical research communications 2008;367(2):271-6.
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2008: Falasca Laura; Farrace Maria Grazia; Rinaldi Alessandra; Tuosto Loretta; Melino Gennard; Piacentini Mauro
Transglutaminase type II is involved in the pathogenesis of endotoxic shock.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(4):2616-24.
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2008: Klanrit Poramaporn; Flinterman Marcella B; Odell Edward W; Melino Gerry; Killick Richard; Norris James S; Tavassoli Mahvash
Specific isoforms of p73 control the induction of cell death induced by the viral proteins, E1A or apoptin.
Cell cycle (Georgetown, Tex.) 2008;7(2):205-15.
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2007: Porzio O; Massa O; Cunsolo V; Colombo C; Malaponti M; Bertuzzi F; Hansen T; Johansen A; Pedersen O; Meschi F; Terrinoni A; Melino G; Federici M; Decarlo N; Menicagli M; Campani D; Marchetti P; Ferdaoussi M; Froguel P; Federici G; Vaxillaire M; Barbetti F
Missense mutations in the TGM2 gene encoding transglutaminase 2 are found in patients with early-onset type 2 diabetes. Mutation in brief no. 982. Online.
Human mutation 2007;28(11):1150.
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2007: Sarang Z; Mádi A; Koy C; Varga S; Glocker M O; Ucker D S; Kuchay S; Chishti A H; Melino G; Fésüs L; Szondy Z
Tissue transglutaminase (TG2) facilitates phosphatidylserine exposure and calpain activity in calcium-induced death of erythrocytes.
Cell death and differentiation 2007;14(10):1842-4.
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2007: Hansen T M; Rossi M; Roperch J P; Ansell K; Simpson K; Taylor D; Mathon N; Knight R A; Melino G
Itch inhibition regulates chemosensitivity in vitro.
Biochemical and biophysical research communications 2007;361(1):33-6.
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2007: Chikh Anissa; Sayan Emre; Thibaut Sebastien; Lena Anna Maria; DiGiorgi Sabrina; Bernard Bruno A; Melino Gerry; Candi Eleonora
Expression of GATA-3 in epidermis and hair follicle: relationship to p63.
Biochemical and biophysical research communications 2007;361(1):1-6.
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2007: Campione Elena; Terrinoni Alessandro; Orlandi Augusto; Codispoti Andrea; Melino Gerry; Bianchi Luca; Mazzotta Annamaria; Garaci Francesco Giuseppe; Ludovici Andrea; Chimenti Sergio
Cerebral cavernomas in a family with multiple cutaneous and uterine leiomyomas associated with a new mutation in the fumarate hydratase gene.
The Journal of investigative dermatology 2007;127(9):2271-3.
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2007: Candi Eleonora; Rufini Alessandro; Terrinoni Alessandro; Giamboi-Miraglia Alessandro; Lena Anna Maria; Mantovani Roberto; Knight Richard; Melino Gerry
DeltaNp63 regulates thymic development through enhanced expression of FgfR2 and Jag2.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(29):11999-2004.
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2007: Oberst Andrew; Malatesta Martina; Aqeilan Rami I; Rossi Mario; Salomoni Paolo; Murillas Rodolfo; Sharma Prashant; Kuehn Michael R; Oren Moshe; Croce Carlo M; Bernassola Francesca; Melino Gerry
The Nedd4-binding partner 1 (N4BP1) protein is an inhibitor of the E3 ligase Itch.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(27):11280-5.
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2007: Zocchi Loredana; Terrinoni Alessandro; Candi Eleonora; Ahvazi Bijan; Bagetta Giacinto; Corasaniti M Tiziana; Lena Anna M; Melino Gerry
Identification of transglutaminase 3 splicing isoforms.
The Journal of investigative dermatology 2007;127(7):1791-4.
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2007: Sayan Berna S; Sayan A Emre; Yang Ai Li; Aqeilan Rami I; Candi Eleonora; Cohen Gerald M; Knight Richard A; Croce Carlo M; Melino Gerry
Cleavage of the transactivation-inhibitory domain of p63 by caspases enhances apoptosis.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(26):10871-6.
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2007: Nicotera Pierluigi; Melino Gerry
Caspase-14 and epidermis maturation.
Nature cell biology 2007;9(6):621-2.
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2007: Mishra Suresh; Melino Gerry; Murphy Liam J
Transglutaminase 2 kinase activity facilitates protein kinase A-induced phosphorylation of retinoblastoma protein.
The Journal of biological chemistry 2007;282(25):18108-15.
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2007: Hooper Claudie; Meimaridou Eirini; Tavassoli Mahvash; Melino Gerry; Lovestone Simon; Killick Richard
p53 is upregulated in Alzheimer's disease and induces tau phosphorylation in HEK293a cells.
Neuroscience letters 2007;418(1):34-7.
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2007: Soond Surinder M; Carroll Christopher; Townsend Paul A; Sayan Emre; Melino Gerry; Behrmann Iris; Knight Richard A; Latchman David S; Stephanou Anastasis
STAT1 regulates p73-mediated Bax gene expression.
FEBS letters 2007;581(6):1217-26.
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2007: McKeon Frank; Melino Gerry
Fog of war: the emerging p53 family.
Cell cycle (Georgetown, Tex.) 2007;6(3):229-32.
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2007: Candi Eleonora; Dinsdale David; Rufini Alessandro; Salomoni Paolo; Knight Richard A; Mueller Martina; Krammer Peter H; Melino Gerry
TAp63 and DeltaNp63 in cancer and epidermal development.
Cell cycle (Georgetown, Tex.) 2007;6(3):274-85.
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2007: Guilluy Christophe; Rolli-Derkinderen Malvyne; Tharaux Pierre-Louis; Melino Gerry; Pacaud Pierre; Loirand Gervaise
Transglutaminase-dependent RhoA activation and depletion by serotonin in vascular smooth muscle cells.
The Journal of biological chemistry 2007;282(5):2918-28.
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2007: Sayan A Emre; Roperch Jean-Pierre; Sayan Berna S; Rossi Mario; Pinkoski M J; Knight Richard A; Willis Anne E; Melino Gerry
Generation of DeltaTAp73 proteins by translation from a putative internal ribosome entry site.
Annals of the New York Academy of Sciences 2007;1095():315-24.
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2007: Battaglia Giuseppe; Farrace Maria Grazia; Mastroberardino Pier Giorgio; Viti Irene; Fimia Gian Maria; Van Beeumen Jozef; Devreese Bart; Melino Gennaro; Molinaro Gemma; Busceti Carla Letizia; Biagioni Francesca; Nicoletti Ferdinando; Piacentini Mauro
Transglutaminase 2 ablation leads to defective function of mitochondrial respiratory complex I affecting neuronal vulnerability in experimental models of extrapyramidal disorders.
Journal of neurochemistry 2007;100(1):36-49.
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2007: Didona Biagio; Codispoti Andrea; Bertini Enrico; Rizzo William B; Carney Gael; Zambruno Giovanna; Dionisi-Vici Carlo; Paradisi Mauro; Pedicelli Cristina; Melino Gerry; Terrinoni Alessandro
Novel and recurrent ALDH3A2 mutations in Italian patients with Sjögren-Larsson syndrome.
Journal of human genetics 2007;52(10):865-70.
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2006: Müller Martina; Schleithoff Elisa Schulze; Stremmel Wolfgang; Melino Gerry; Krammer Peter H; Schilling Tobias
One, two, three--p53, p63, p73 and chemosensitivity.
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2006;9(6):288-306.
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2006: Bellodi Cristian; Kindle Karin; Bernassola Francesca; Cossarizza Andrea; Dinsdale David; Melino Gerry; Heery David; Salomoni Paolo
A cytoplasmic PML mutant inhibits p53 function.
Cell cycle (Georgetown, Tex.) 2006;5(22):2688-92.
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2006: Candi Eleonora; Terrinoni Alessandro; Rufini Alessandro; Chikh Anissa; Lena Anna Maria; Suzuki Yasuhiro; Sayan Berna S; Knight Richard A; Melino Gerry
p63 is upstream of IKK alpha in epidermal development.
Journal of cell science 2006;119(Pt 22):4617-22.
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2006: Hooper Claudie; Tavassoli Mahvash; Chapple J Paul; Uwanogho Dafe; Goodyear Richard; Melino Gerry; Lovestone Simon; Killick Richard
TAp73 isoforms antagonize Notch signalling in SH-SY5Y neuroblastomas and in primary neurones.
Journal of neurochemistry 2006;99(3):989-99.
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2006: Viganò M Alessandra; Lamartine Jérôme; Testoni Barbara; Merico Daniele; Alotto Daniela; Castagnoli Carlotta; Robert Amèlie; Candi Eleonora; Melino Gerry; Gidrol Xavier; Mantovani Roberto
New p63 targets in keratinocytes identified by a genome-wide approach.
The EMBO journal 2006;25(21):5105-16.
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2006: Ponassi Raffaella; Terrinoni Alessandro; Chikh Anissa; Rufini Alessandro; Lena Anna Maria; Sayan Berna S; Melino Gerry; Candi Eleonora
p63 and p73, members of the p53 gene family, transactivate PKCdelta.
Biochemical pharmacology 2006;72(11):1417-22.
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2006: Barcaroli D; Dinsdale D; Neale M H; Bongiorno-Borbone L; Ranalli M; Munarriz E; Sayan A E; McWilliam J M; Smith T M; Fava E; Knight R A; Melino G; De Laurenzi V
FLASH is an essential component of Cajal bodies.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(40):14802-7.
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2006: Barcaroli D; Bongiorno-Borbone L; Terrinoni A; Hofmann T G; Rossi M; Knight R A; Matera A G; Melino G; De Laurenzi V
FLASH is required for histone transcription and S-phase progression.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(40):14808-12.
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2006: Szondy Z; Mastroberardino P G; Váradi J; Farrace M G; Nagy N; Bak I; Viti I; Wieckowski M R; Melino G; Rizzuto R; Tósaki A; Fesus L; Piacentini M
Tissue transglutaminase (TG2) protects cardiomyocytes against ischemia/reperfusion injury by regulating ATP synthesis.
Cell death and differentiation 2006;13(10):1827-9.
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2006: Mastroberardino Pier Giorgio; Farrace Maria Grazia; Viti Irene; Pavone Flaminia; Fimia Gian Maria; Melino Gennaro; Rodolfo Carlo; Piacentini Mauro
"Tissue" transglutaminase contributes to the formation of disulphide bridges in proteins of mitochondrial respiratory complexes.
Biochimica et biophysica acta 2006;1757(9-10):1357-65.
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2006: Jones R A; Kotsakis P; Johnson T S; Chau D Y S; Ali S; Melino G; Griffin M
Matrix changes induced by transglutaminase 2 lead to inhibition of angiogenesis and tumor growth.
Cell death and differentiation 2006;13(9):1442-53.
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2006: Melino Gerry; Knight Richard A; Cesareni Gianni
Degradation of p63 by Itch.
Cell cycle (Georgetown, Tex.) 2006;5(16):1735-9.
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2006: Rossi Mario; Aqeilan Rami I; Neale Michael; Candi Eleonora; Salomoni Paolo; Knight Richard A; Croce Carlo M; Melino Gerry
The E3 ubiquitin ligase Itch controls the protein stability of p63.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(34):12753-8.
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2006: Candi E; Rufini A; Terrinoni A; Dinsdale D; Ranalli M; Paradisi A; De Laurenzi V; Spagnoli L G; Catani M V; Ramadan S; Knight R A; Melino G
Differential roles of p63 isoforms in epidermal development: selective genetic complementation in p63 null mice.
Cell death and differentiation 2006;13(6):1037-47.
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2006: Hooper Claudie; Killick Richard; Tavassoli Mahvash; Melino Gerry; Lovestone Simon
TAp73alpha induces tau phosphorylation in HEK293a cells via a transcription-dependent mechanism.
Neuroscience letters 2006;401(1-2):30-4.
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2006: Bellodi Cristian; Kindle Karin; Bernassola Francesca; Dinsdale David; Cossarizza Andrea; Melino Gerry; Heery David; Salomoni Paolo
Cytoplasmic function of mutant promyelocytic leukemia (PML) and PML-retinoic acid receptor-alpha.
The Journal of biological chemistry 2006;281(20):14465-73.
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2006: Sayan Berna S; Sayan A Emre; Knight Richard A; Melino Gerry; Cohen Gerald M
p53 is cleaved by caspases generating fragments localizing to mitochondria.
The Journal of biological chemistry 2006;281(19):13566-73.
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2006: Rufini Alessandro; Weil Miguel; McKeon Frank; Barlattani Alberto; Melino Gerry; Candi Eleonora
p63 protein is essential for the embryonic development of vibrissae and teeth.
Biochemical and biophysical research communications 2006;340(3):737-41.
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2006: Cicero Daniel O; Falconi Mattia; Candi Eleonora; Mele Sonia; Cadot Bruno; Di Venere Almerinda; Rufini Stefano; Melino Gerry; Desideri Alessandro
NMR structure of the p63 SAM domain and dynamical properties of G534V and T537P pathological mutants, identified in the AEC syndrome.
Cell biochemistry and biophysics 2006;44(3):475-89.
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2005: Cassidy Andrew J; van Steensel Maurice A M; Steijlen Peter M; van Geel Michel; van der Velden Jaap; Morley Susan M; Terrinoni Alessandro; Melino Gerry; Candi Eleonora; McLean W H Irwin
A homozygous missense mutation in TGM5 abolishes epidermal transglutaminase 5 activity and causes acral peeling skin syndrome.
American journal of human genetics 2005;77(6):909-17.
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2005: Nicotera Pierluigi; Melino Gerry
Neurodevelopment on route p63.
Neuron 2005;48(5):707-9.
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2005: Müller M; Schilling T; Sayan A E; Kairat A; Lorenz K; Schulze-Bergkamen H; Oren M; Koch A; Tannapfel A; Stremmel W; Melino G; Krammer P H
TAp73/Delta Np73 influences apoptotic response, chemosensitivity and prognosis in hepatocellular carcinoma.
Cell death and differentiation 2005;12(12):1564-77.
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2005: Bernassola Francesca; Oberst Andrew; Melino Gerry; Pandolfi Pier Paolo
The promyelocytic leukaemia protein tumour suppressor functions as a transcriptional regulator of p63.
Oncogene 2005;24(46):6982-6.
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2005: Thibaut Sébastien; Candi Eleonora; Pietroni Valentina; Melino Gerry; Schmidt Rainer; Bernard Bruno A
Transglutaminase 5 expression in human hair follicle.
The Journal of investigative dermatology 2005;125(3):581-5.
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2005: Sarang Zsolt; Molnár Péter; Németh Tamás; Gomba Szabolcs; Kardon Tamás; Melino Gerry; Cotecchia Susanna; Fésüs László; Szondy Zsuzsa
Tissue transglutaminase (TG2) acting as G protein protects hepatocytes against Fas-mediated cell death in mice.
Hepatology (Baltimore, Md.) 2005;42(3):578-87.
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2005: Munarriz Eliana; Bano Daniele; Sayan A Emre; Rossi Mario; Melino Gerry; Nicotera Pierluigi
Calpain cleavage regulates the protein stability of p73.
Biochemical and biophysical research communications 2005;333(3):954-60.
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2005: Corasaniti M T; Russo R; Amantea D; Gliozzi M; Siviglia E; Stringaro A R; Malorni W; Melino G; Bagetta G
Neuroprotection by the caspase-1 inhibitor Ac-YVAD-(acyloxy)mk in experimental neuroAIDS is independent from IL-1beta generation.
Cell death and differentiation 2005;12 Suppl 1():999-1001.
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2005: Gressner Olav; Schilling Tobias; Lorenz Katja; Schulze Schleithoff Elisa; Koch Andreas; Schulze-Bergkamen Henning; Lena Anna Maria; Candi Eleonora; Terrinoni Alessandro; Catani Maria Valeria; Oren Moshe; Melino Gerry; Krammer Peter H; Stremmel Wolfgang; Müller Martina
TAp63alpha induces apoptosis by activating signaling via death receptors and mitochondria.
The EMBO journal 2005;24(13):2458-71.
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2005: Falasca Laura; Iadevaia Valentina; Ciccosanti Fabiola; Melino Gennaro; Serafino Annalucia; Piacentini Mauro
Transglutaminase type II is a key element in the regulation of the anti-inflammatory response elicited by apoptotic cell engulfment.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(11):7330-40.
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2005: Ramadan Saafa; Terrinoni Alessandro; Catani Maria Valeria; Sayan A Emre; Knight Richard A; Mueller Martina; Krammer Peter H; Melino Gerry; Candi Eleonora
p73 induces apoptosis by different mechanisms.
Biochemical and biophysical research communications 2005;331(3):713-7.
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2005: Oberst Andrew; Rossi Mario; Salomoni Paolo; Pandolfi Pier Paolo; Oren Moshe; Melino Gerry; Bernassola Francesca
Regulation of the p73 protein stability and degradation.
Biochemical and biophysical research communications 2005;331(3):707-12.
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2005: Candi Eleonora; Schmidt Rainer; Melino Gerry
The cornified envelope: a model of cell death in the skin.
Nature reviews. Molecular cell biology 2005;6(4):328-40.
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2005: Sayan A Emre; Paradisi Andrea; Vojtesek Borek; Knight Richard A; Melino Gerry; Candi Eleonora
New antibodies recognizing p73: comparison with commercial antibodies.
Biochemical and biophysical research communications 2005;330(1):186-93.
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2005: Catani Maria Valeria; Savini Isabella; Rossi Antonello; Melino Gerry; Avigliano Luciana
Biological role of vitamin C in keratinocytes.
Nutrition reviews 2005;63(3):81-90.
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2005: Rossi Mario; De Laurenzi Vincenzo; Munarriz Eliana; Green Douglas R; Liu Yun-Cai; Vousden Karen H; Cesareni Gianni; Melino Gerry
The ubiquitin-protein ligase Itch regulates p73 stability.
The EMBO journal 2005;24(4):836-48.
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2005: Flinterman Marcella; Guelen Lars; Ezzati-Nik Samira; Killick Richard; Melino Gerry; Tominaga Kazuya; Mymryk Joe S; Gäken Joop; Tavassoli Mahvash
E1A activates transcription of p73 and Noxa to induce apoptosis.
The Journal of biological chemistry 2005;280(7):5945-59.
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2005: Ameisen Jean-claude; Chikh Anissa; Bongiorno-Borbone Lucilla; Knight Richard A; Melino Gerry
[This death which is necessary for life]
Journal de la Société de biologie 2005;199(3):267-76.
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2004: Rossi Mario; Sayan A Emre; Terrinoni Alessandro; Melino Gerry; Knight Richard A
Mechanism of induction of apoptosis by p73 and its relevance to neuroblastoma biology.
Annals of the New York Academy of Sciences 2004;1028():143-9.
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2004: Munarriz Eliana; Barcaroli Daniela; Stephanou Anastasis; Townsend Paul A; Maisse Carine; Terrinoni Alessandro; Neale Michael H; Martin Seamus J; Latchman David S; Knight Richard A; Melino Gerry; De Laurenzi Vincenzo
PIAS-1 is a checkpoint regulator which affects exit from G1 and G2 by sumoylation of p73.
Molecular and cellular biology 2004;24(24):10593-610.
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2004: Terrinoni Alessandro; Cocuroccia Barbara; Gubinelli Emanuela; Zambruno Giovanna; Candi Eleonora; Melino Gerry; Girolomoni Giampiero
Identification of the keratin K9 R162W mutation in patients of Italian origin with epidermolytic palmoplantar keratoderma.
European journal of dermatology : EJD 2004;14(6):375-8.
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2004: Rufini A; Vilbois F; Paradisi A; Oddi S; Tartaglione R; Leta A; Bagetta G; Guerrieri P; Finazzi-Agro' A; Melino G; Candi E
Transglutaminase 5 is acetylated at the N-terminal end.
Amino acids 2004;26(4):425-30.
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2004: Cadot B; Rufini A; Pietroni V; Ramadan S; Guerrieri P; Melino G; Candi E
Overexpressed transglutaminase 5 triggers cell death.
Amino acids 2004;26(4):405-8.
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2004: Candi Eleonora; Paradisi Andrea; Terrinoni Alessandro; Pietroni Valentina; Oddi Sergio; Cadot Bruno; Jogini Vishwanath; Meiyappan Muthuraman; Clardy Jon; Finazzi-Agro Alessandro; Melino Gerry
Transglutaminase 5 is regulated by guanine-adenine nucleotides.
The Biochemical journal 2004;381(Pt 1):313-9.
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2004: Terron-Kwiatkowski A; Terrinoni A; Didona B; Melino G; Atherton D J; Irvine A D; McLean W H I
Atypical epidermolytic palmoplantar keratoderma presentation associated with a mutation in the keratin 1 gene.
The British journal of dermatology 2004;150(6):1096-103.
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2004: Bernassola Francesca; Salomoni Paolo; Oberst Andrew; Di Como Charles J; Pagano Michele; Melino Gerry; Pandolfi Pier Paolo
Ubiquitin-dependent degradation of p73 is inhibited by PML.
The Journal of experimental medicine 2004;199(11):1545-57.
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2004: Maisse C; Munarriz E; Barcaroli D; Melino G; De Laurenzi V
DNA damage induces the rapid and selective degradation of the DeltaNp73 isoform, allowing apoptosis to occur.
Cell death and differentiation 2004;11(6):685-7.
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2004: Terrinoni Alessandro; Ranalli Marco; Cadot Bruno; Leta Aida; Bagetta Giacinto; Vousden Karen H; Melino Gerry
p73-alpha is capable of inducing scotin and ER stress.
Oncogene 2004;23(20):3721-5.
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2004: Nicotera Pierluigi; Melino Gerry
Regulation of the apoptosis-necrosis switch.
Oncogene 2004;23(16):2757-65.
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2004: Falconi Mattia; Melino Gerry; Desideri Alessandro
Molecular dynamics simulation of the C-terminal sterile alpha-motif domain of human p73alpha: evidence of a dynamical relationship between helices 3 and 5.
Biochemical and biophysical research communications 2004;316(4):1037-42.
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2004: Terrinoni Alessandro; Leta Aida; Pedicelli Cristina; Candi Eleonora; Ranalli Marco; Puddu Pietro; Paradis Mauro; Angelo Corrado; Bagetta Giancinto; Melino Gerry;
A novel recessive connexin 31 (GJB3) mutation in a case of erythrokeratodermia variabilis.
The Journal of investigative dermatology 2004;122(3):837-9.
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2004: Aqeilan Rami I; Pekarsky Yuri; Herrero Juan J; Palamarchuk Alexey; Letofsky Jean; Druck Teresa; Trapasso Francesco; Han Shuang-Yin; Melino Gerry; Huebner Kay; Croce Carlo M
Functional association between Wwox tumor suppressor protein and p73, a p53 homolog.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(13):4401-6.
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2004: Billon Nathalie; Terrinoni Alessandro; Jolicoeur Christine; McCarthy Afshan; Richardson William D; Melino Gerry; Raff Martin
Roles for p53 and p73 during oligodendrocyte development.
Development (Cambridge, England) 2004;131(6):1211-20.
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2004: Freitag Tobias; Schulze-Koops Hendrik; Niedobitek Gerald; Melino Gerry; Schuppan Detlef
The role of the immune response against tissue transglutaminase in the pathogenesis of coeliac disease.
Autoimmunity reviews 2004;3(2):13-20.
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2004: Melino Gerry; Bernassola Francesca; Ranalli Marco; Yee Karen; Zong Wei Xing; Corazzari Marco; Knight Richard A; Green Doug R; Thompson Craig; Vousden Karen H
p73 Induces apoptosis via PUMA transactivation and Bax mitochondrial translocation.
The Journal of biological chemistry 2004;279(9):8076-83.
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2004: Sayan A Emre; Rossi Mario; Melino Gerry; Knight Richard A
p73: in silico evidence for a putative third promoter region.
Biochemical and biophysical research communications 2004;313(3):765-70.
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2003: Melino Gerry
p73, the "assistant" guardian of the genome?
Annals of the New York Academy of Sciences 2003;1010():9-15.
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2003: Melino Gerry; Lu Xin; Gasco Milena; Crook Tim; Knight Richard A
Functional regulation of p73 and p63: development and cancer.
Trends in biochemical sciences 2003;28(12):663-70.
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2003: Lovat Penny E; Oliverio Serafina; Corazzari Marco; Rodolfo Carlo; Ranalli Marco; Goranov Bojidar; Melino Gerry; Redfern Christopher P F; Piacentini Mauro
Bak: a downstream mediator of fenretinide-induced apoptosis of SH-SY5Y neuroblastoma cells.
Cancer research 2003;63(21):7310-3.
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2003: Savini Isabella; Catani Maria Valeria; Rossi Antonello; Duranti Guglielmo; Ranalli Marco; Melino Gerry; Sabatini Stefania; Avigliano Luciana
Vitamin C recycling is enhanced in the adaptive response to leptin-induced oxidative stress in keratinocytes.
The Journal of investigative dermatology 2003;121(4):786-93.
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2003: Maisse Carine; Guerrieri Piero; Melino Gerry
p73 and p63 protein stability: the way to regulate function?
Biochemical pharmacology 2003;66(8):1555-61.
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2003: Verderio Elisabetta A M; Telci Dilek; Okoye Afam; Melino Gerry; Griffin Martin
A novel RGD-independent cel adhesion pathway mediated by fibronectin-bound tissue transglutaminase rescues cells from anoikis.
The Journal of biological chemistry 2003;278(43):42604-14.
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2003: Lovat Penny E; Oliverio Serafina; Corazzari Marco; Ranalli Marco; Pearson Andy D J; Melino Gerry; Piacentini Mauro; Redfern Christopher P F
Induction of GADD153 and Bak: novel molecular targets of fenretinide-induced apoptosis of neuroblastoma.
Cancer letters 2003;197(1-2):157-63.
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2003: Lovat Penny E; Ranalli Marco; Corazzari Marco; Raffaghello Lizzia; Pearson Andy D J; Ponzoni Mirco; Piacentini Mauro; Melino Gerry; Redfern Christopher P F
Mechanisms of free-radical induction in relation to fenretinide-induced apoptosis of neuroblastoma.
Journal of cellular biochemistry 2003;89(4):698-708.
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2003: Marulli G C; Campione E; Chimenti M S; Terrinoni A; Melino G; Bianchi L
Type I lamellar ichthyosis improved by tazarotene 0.1% gel.
Clinical and experimental dermatology 2003;28(4):391-3.
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2003: Szondy Zsuzsa; Sarang Zsolt; Molnar Peter; Nemeth Tamas; Piacentini Mauro; Mastroberardino Pier Giorgio; Falasca Laura; Aeschlimann Daniel; Kovacs Judit; Kiss Ildiko; Szegezdi Eva; Lakos Gabriella; Rajnavolgyi Eva; Birckbichler Paul J; Melino Gerry; Fesus Laszlo
Transglutaminase 2-/- mice reveal a phagocytosis-associated crosstalk between macrophages and apoptotic cells.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(13):7812-7.
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2003: Nardacci Roberta; Lo Iacono Oreste; Ciccosanti Fabiola; Falasca Laura; Addesso Maria; Amendola Alessandra; Antonucci Giorgio; Craxì Antonio; Fimia Gian Maria; Iadevaia Valentina; Melino Gerry; Ruco Luigi; Tocci Guido; Ippolito Giuseppe; Piacentini Mauro
Transglutaminase type II plays a protective role in hepatic injury.
The American journal of pathology 2003;162(4):1293-303.
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2003: Catani Maria Valeria; Corasaniti Maria Tiziana; Ranalli Marco; Amantea Diana; Litovchick Alexander; Lapidot Aviva; Melino Gerry
The Tat antagonist neomycin B hexa-arginine conjugate inhibits gp-120-induced death of human neuroblastoma cells.
Journal of neurochemistry 2003;84(6):1237-45.
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2003: Knight Richard A; Candi Eleonora; Melino Gerry
The p53 homology trap.
Cancer biology & therapy 2003;2(1):63-6.
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2003: Lahm Armin; Paradisi Andrea; Green Douglas R; Melino Gerry
Death fold domain interaction in apoptosis.
Cell death and differentiation 2003;10(1):10-2.
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2002: Lovat Penny E; Oliverio Serafina; Ranalli Marco; Corazzari Marco; Rodolfo Carlo; Bernassola Francesca; Aughton Karen; Maccarrone Mauro; Hewson Quentin D Campbell; Pearson Andy D J; Melino Gerry; Piacentini Mauro; Redfern Christopher P F
GADD153 and 12-lipoxygenase mediate fenretinide-induced apoptosis of neuroblastoma.
Cancer research 2002;62(18):5158-67.
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2002: Candi Eleonora; Oddi Sergio; Paradisi Andrea; Terrinoni Alessandro; Ranalli Marco; Teofoli Patrizia; Citro Gennaro; Scarpato Silvia; Puddu Pietro; Melino Gerry
Expression of transglutaminase 5 in normal and pathologic human epidermis.
The Journal of investigative dermatology 2002;119(3):670-7.
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2002: Bernassola Francesca; Federici Massimo; Corazzari Marco; Terrinoni Alessandro; Hribal Marta L; De Laurenzi Vincenzo; Ranalli Marco; Massa Ornella; Sesti Giorgio; McLean W H Irwin; Citro Gennaro; Barbetti Fabrizio; Melino Gerry
Role of transglutaminase 2 in glucose tolerance: knockout mice studies and a putative mutation in a MODY patient.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002;16(11):1371-8.
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2002: Mastroberardino P G; Iannicola C; Nardacci R; Bernassola F; De Laurenzi V; Melino G; Moreno S; Pavone F; Oliverio S; Fesus L; Piacentini M
'Tissue' transglutaminase ablation reduces neuronal death and prolongs survival in a mouse model of Huntington's disease.
Cell death and differentiation 2002;9(9):873-80.
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2002: Pucci Bruna; Claudio Pier Paolo; Masciullo Valeria; Bellincampi Lorenza; Terrinoni Alessandro; Khalili Kamel; Melino Gerry; Giordano Antonio
pRb2/p130 promotes radiation-induced cell death in the glioblastoma cell line HJC12 by p73 upregulation and Bcl-2 downregulation.
Oncogene 2002;21(38):5897-905.
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2002: Melino Gerry; De Laurenzi Vincenzo; Vousden Karen H
p73: Friend or foe in tumorigenesis.
Nature reviews. Cancer 2002;2(8):605-15.
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2002: Catani M Valeria; Costanzo Antonio; Savini Isabella; Levrero Massimo; de Laurenzi Vincenzo; Wang Jean Y J; Melino Gerry; Avigliano Luciana
Ascorbate up-regulates MLH1 (Mut L homologue-1) and p73: implications for the cellular response to DNA damage.
The Biochemical journal 2002;364(Pt 2):441-7.
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2002: Melino Gerry
The meaning of death.
Cell death and differentiation 2002;9(4):347-8.
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2002: Bernassola Francesca; Boumis Giovanna; Corazzari Marco; Bertini Giuseppe; Citro Gennaro; Knight Richard A; Amiconi Gino; Melino Gerry
Osmotic resistance of high-density erythrocytes in transglutaminase 2-deficient mice.
Biochemical and biophysical research communications 2002;291(5):1123-7.
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2002: Savini Isabella; Catani Maria Valeria; Rossi Antonello; Duranti Guglielmo; Melino Gerry; Avigliano Luciana
Characterization of keratinocyte differentiation induced by ascorbic acid: protein kinase C involvement and vitamin C homeostasis.
The Journal of investigative dermatology 2002;118(2):372-9.
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2001: Terrinoni A; Smith F J; Didona B; Canzona F; Paradisi M; Huber M; Hohl D; David A; Verloes A; Leigh I M; Munro C S; Melino G; McLean W H
Novel and recurrent mutations in the genes encoding keratins K6a, K16 and K17 in 13 cases of pachyonychia congenita.
The Journal of investigative dermatology 2001;117(6):1391-6.
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2001: Grob T J; Novak U; Maisse C; Barcaroli D; Lüthi A U; Pirnia F; Hügli B; Graber H U; De Laurenzi V; Fey M F; Melino G; Tobler A
Human delta Np73 regulates a dominant negative feedback loop for TAp73 and p53.
Cell death and differentiation 2001;8(12):1213-23.
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2001: Candi E; Oddi S; Terrinoni A; Paradisi A; Ranalli M; Finazzi-Agró A; Melino G
Transglutaminase 5 cross-links loricrin, involucrin, and small proline-rich proteins in vitro.
The Journal of biological chemistry 2001;276(37):35014-23.
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2001: Maccarrone M; Melino G; Finazzi-Agrò A
Lipoxygenases and their involvement in programmed cell death.
Cell death and differentiation 2001;8(8):776-84.
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2001: Yang J M; Ahn K S; Cho M O; Yoneda K; Lee C H; Lee J H; Lee E S; Candi E; Melino G; Ahvazi B; Steinert P M
Novel mutations of the transglutaminase 1 gene in lamellar ichthyosis.
The Journal of investigative dermatology 2001;117(2):214-8.
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2001: Federici M; Hribal M; Perego L; Ranalli M; Caradonna Z; Perego C; Usellini L; Nano R; Bonini P; Bertuzzi F; Marlier L N; Davalli A M; Carandente O; Pontiroli A E; Melino G; Marchetti P; Lauro R; Sesti G; Folli F
High glucose causes apoptosis in cultured human pancreatic islets of Langerhans: a potential role for regulation of specific Bcl family genes toward an apoptotic cell death program.
Diabetes 2001;50(6):1290-301.
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2001: Catani M V; Rossi A; Costanzo A; Sabatini S; Levrero M; Melino G; Avigliano L
Induction of gene expression via activator protein-1 in the ascorbate protection against UV-induced damage.
The Biochemical journal 2001;356(Pt 1):77-85.
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2001: Bernassola F; Catani M V; Corazzari M; Rossi A; Melino G
Inactivation of multiple targets by nitric oxide in CD95-triggered apoptosis.
Journal of cellular biochemistry 2001;82(1):123-33.
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2001: Annicchiarico-Petruzzelli M; Bernassola F; Lovat P E; Redfern C P; Pearson A D; Melino G
Apoptosis in neuroblastomas induced by interferon-gamma involves the CD95/CD95L pathway.
Medical and pediatric oncology 2001;36(1):115-7.
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2001: De Laurenzi V; Melino G
Gene disruption of tissue transglutaminase.
Molecular and cellular biology 2001;21(1):148-55.
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2001: Federici M; Hribal M L; Ranalli M; Marselli L; Porzio O; Lauro D; Borboni P; Lauro R; Marchetti P; Melino G; Sesti G
The common Arg972 polymorphism in insulin receptor substrate-1 causes apoptosis of human pancreatic islets.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(1):22-24.
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2000: Lovat P E; Ranalli M; Bernassola F; Tilby M; Malcolm A J; Pearson A D; Piacentini M; Melino G; Redfern C P
Distinct properties of fenretinide and CD437 lead to synergistic responses with chemotherapeutic reagents.
Medical and pediatric oncology 2000;35(6):663-8.
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2000: Lovat P E; Ranalli M; Bernassola F; Tilby M; Malcolm A J; Pearson A D; Piacentini M; Melino G; Redfern C P
Synergistic induction of apoptosis of neuroblastoma by fenretinide or CD437 in combination with chemotherapeutic drugs.
International journal of cancer. Journal international du cancer 2000;88(6):977-85.
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2000: Tschan M P; Grob T J; Peters U R; Laurenzi V D; Huegli B; Kreuzer K A; Schmidt C A; Melino G; Fey M F; Tobler A; Cajot J F
Enhanced p73 expression during differentiation and complex p73 isoforms in myeloid leukemia.
Biochemical and biophysical research communications 2000;277(1):62-5.
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2000: Lovat P E; Ranalli M; Annichiarrico-Petruzzelli M; Bernassola F; Piacentini M; Malcolm A J; Pearson A D; Melino G; Redfern C P
Effector mechanisms of fenretinide-induced apoptosis in neuroblastoma.
Experimental cell research 2000;260(1):50-60.
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2000: Rossi A; Catani M V; Candi E; Bernassola F; Puddu P; Melino G
Nitric oxide inhibits cornified envelope formation in human keratinocytes by inactivating transglutaminases and activating protein 1.
The Journal of investigative dermatology 2000;115(4):731-9.
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2000: Maccarrone M; Lorenzon T; Bari M; Melino G; Finazzi-Agro A
Anandamide induces apoptosis in human cells via vanilloid receptors. Evidence for a protective role of cannabinoid receptors.
The Journal of biological chemistry 2000;275(41):31938-45.
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2000: De Laurenzi V; Rossi A; Terrinoni A; Barcaroli D; Levrero M; Costanzo A; Knight R A; Guerrieri P; Melino G
p63 and p73 transactivate differentiation gene promoters in human keratinocytes.
Biochemical and biophysical research communications 2000;273(1):342-6.
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2000: Terrinoni A; Puddu P; Didona B; De Laurenzi V; Candi E; Smith F J; McLean W H; Melino G
A mutation in the V1 domain of K16 is responsible for unilateral palmoplantar verrucous nevus.
The Journal of investigative dermatology 2000;114(6):1136-40.
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2000: Maccarrone M; Ranalli M; Bellincampi L; Salucci M L; Sabatini S; Melino G; Finazzi-Agrò A
Activation of different lipoxygenase isozymes induces apoptosis in human erythroleukemia and neuroblastoma cells.
Biochemical and biophysical research communications 2000;272(2):345-50.
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2000: Catani M V; Corasaniti M T; Navarra M; Nisticò G; Finazzi-Agrò A; Melino G
gp120 induces cell death in human neuroblastoma cells through the CXCR4 and CCR5 chemokine receptors.
Journal of neurochemistry 2000;74(6):2373-9.
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2000: Melino G; Bernassola F; Catani M V; Rossi A; Corazzari M; Sabatini S; Vilbois F; Green D R
Nitric oxide inhibits apoptosis via AP-1-dependent CD95L transactivation.
Cancer research 2000;60(9):2377-83.
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2000: De Laurenzi V; Raschellá G; Barcaroli D; Annicchiarico-Petruzzelli M; Ranalli M; Catani M V; Tanno B; Costanzo A; Levrero M; Melino G
Induction of neuronal differentiation by p73 in a neuroblastoma cell line.
The Journal of biological chemistry 2000;275(20):15226-31.
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2000: Melino G; Catani M V; Corazzari M; Guerrieri P; Bernassola F
Nitric oxide can inhibit apoptosis or switch it into necrosis.
Cellular and molecular life sciences : CMLS 2000;57(4):612-22.
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2000: Bernardini S; Bernassola F; Cortese C; Ballerini S; Melino G; Motti C; Bellincampi L; Iori R; Federici G
Modulation of GST P1-1 activity by polymerization during apoptosis.
Journal of cellular biochemistry 2000;77(4):645-53.
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2000: Richard G; Brown N; Smith L E; Terrinoni A; Melino G; Mackie R M; Bale S J; Uitto J
The spectrum of mutations in erythrokeratodermias--novel and de novo mutations in GJB3.
Human genetics 2000;106(3):321-9.
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2000: Candi E; Paci M; Oddi S; Paradisi A; Guerrieri P; Melino G
Ordered structure acquisition by the N- and C-terminal domains of the small proline-rich 3 protein.
Journal of cellular biochemistry 2000;77(2):179-85.
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2000: Terrinoni A; Candi E; Oddi S; Gobello T; Camaione D B; Mazzanti C; Zambruno G; Knight R; Melino G
A glutamine insertion in the 1A alpha helical domain of the keratin 4 gene in a familial case of white sponge nevus.
The Journal of investigative dermatology 2000;114(2):388-91.
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2000: Vernole P; Terrinoni A; Didona B; De Laurenzi V; Rossi P; Melino G; Grimaldi P
An SRY-negative XX male with Huriez syndrome.
Clinical genetics 2000;57(1):61-6.
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2000: De Laurenzi V; Melino G
Evolution of functions within the p53/p63/p73 family.
Annals of the New York Academy of Sciences 2000;926():90-100.
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2000: Melino G; Candi E; Steinert P M
Assays for transglutaminases in cell death.
Methods in enzymology 2000;322():433-72.
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1999: Bernardini S; Melino G; Cortese C; Ballerini S; Annicchiarico-Petruzzelli M; Bernassola F; Corazzari M; Federici G
Modulation of glutathione transferase P1-1 activity by retinoic acid in neuroblastoma cells.
Journal of cellular biochemistry 1999;75(3):375-81.
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1999: Maccarrone M; Salucci M L; Melino G; Rosato N; Finazzi-Agro A
The early phase of apoptosis in human neuroblastoma CHP100 cells is characterized by lipoxygenase-dependent ultraweak light emission.
Biochemical and biophysical research communications 1999;265(3):758-62.
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1999: Nicotera P; Bernassola F; Melino G
Nitric oxide (NO), a signaling molecule with a killer soul.
Cell death and differentiation 1999;6(10):931-3.
-
1999: Pucci B; Bellincampi L; Tafani M; Masciullo V; Melino G; Giordano A
Paclitaxel induces apoptosis in Saos-2 cells with CD95L upregulation and Bcl-2 phosphorylation.
Experimental cell research 1999;252(1):134-43.
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1999: Steinert P M; Candi E; Tarcsa E; Marekov L N; Sette M; Paci M; Ciani B; Guerrieri P; Melino G
Transglutaminase crosslinking and structural studies of the human small proline rich 3 protein.
Cell death and differentiation 1999;6(9):916-30.
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1999: Candi E; Melino G; Sette M; Oddi S; Guerrieri P; Paci M
Acquisition of ordered conformation by the N-terminal domain of the human small proline rich 2 protein.
Biochemical and biophysical research communications 1999;262(2):395-400.
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1999: Bernassola F; Scheuerpflug C; Herr I; Krammer P H; Debatin K M; Melino G
Induction of apoptosis by IFNgamma in human neuroblastoma cell lines through the CD95/CD95L autocrine circuit.
Cell death and differentiation 1999;6(7):652-60.
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1999: De Laurenzi V D; Catani M V; Terrinoni A; Corazzari M; Melino G; Costanzo A; Levrero M; Knight R A
Additional complexity in p73: induction by mitogens in lymphoid cells and identification of two new splicing variants epsilon and zeta.
Cell death and differentiation 1999;6(5):389-90.
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1999: Savini I; D'Angelo I; Ranalli M; Melino G; Avigliano L
Ascorbic acid maintenance in HaCaT cells prevents radical formation and apoptosis by UV-B.
Free radical biology & medicine 1999;26(9-10):1172-80.
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1999: Lovat P E; Annicchiarico-Petruzzelli M; Corazzari M; Dobson M G; Malcolm A J; Pearson A D; Melino G; Redfern C P
Differential effects of retinoic acid isomers on the expression of nuclear receptor co-regulators in neuroblastoma.
FEBS letters 1999;445(2-3):415-9.
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1999: Piredda L; Farrace M G; Lo Bello M; Malorni W; Melino G; Petruzzelli R; Piacentini M
Identification of 'tissue' transglutaminase binding proteins in neural cells committed to apoptosis.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1999;13(2):355-64.
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1999: Vernole P; Tullio A; Caporossi D; Didona B; Melino G; Tedeschi B
Bleomycin-induced chromosome aberrations in lymphocytes derived from patients with lamellar ichthyosis.
Cancer genetics and cytogenetics 1999;108(2):154-7.
-
1999: Bernassola F; Rossi A; Melino G
Regulation of transglutaminases by nitric oxide.
Annals of the New York Academy of Sciences 1999;887():83-91.
-
1998: De Laurenzi V; Costanzo A; Barcaroli D; Terrinoni A; Falco M; Annicchiarico-Petruzzelli M; Levrero M; Melino G
Two new p73 splice variants, gamma and delta, with different transcriptional activity.
The Journal of experimental medicine 1998;188(9):1763-8.
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1998: Maccarrone M; Fantini C; Ranalli M; Melino G; Agrò A F
Activation of nitric oxide synthase is involved in tamoxifen-induced apoptosis of human erythroleukemia K562 cells.
FEBS letters 1998;434(3):421-4.
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1998: Catani M V; Bernassola F; Rossi A; Melino G
Inhibition of clotting factor XIII activity by nitric oxide.
Biochemical and biophysical research communications 1998;249(1):275-8.
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1998: Melino G; Piacentini M
'Tissue' transglutaminase in cell death: a downstream or a multifunctional upstream effector?
FEBS letters 1998;430(1-2):59-63.
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1998: Vernole P; Tedeschi B; Caporossi D; Maccarrone M; Melino G; Annicchiarico-Petruzzelli M
Induction of apoptosis by bleomycin in resting and cycling human lymphocytes.
Mutagenesis 1998;13(3):209-15.
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1998: Corasaniti M T; Navarra M; Nisticò S; Rotiroti D; Maccarrone M; Melino G; Finazzi-Agrò A
Requirement for membrane lipid peroxidation in HIV-1 gp120-induced neuroblastoma cell death.
Biochemical and biophysical research communications 1998;246(3):686-9.
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1998: Candi E; Melino G; Lahm A; Ceci R; Rossi A; Kim I G; Ciani B; Steinert P M
Transglutaminase 1 mutations in lamellar ichthyosis. Loss of activity due to failure of activation by proteolytic processing.
The Journal of biological chemistry 1998;273(22):13693-702.
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1998: Maccarrone M; Bellincampi L; Melino G; Finazzi Agrò A
Cholesterol, but not its esters, triggers programmed cell death in human erythroleukemia K562 cells.
European journal of biochemistry / FEBS 1998;253(1):107-13.
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1998: Savini I; D'Angelo I; Annicchiarico-Petruzzelli M; Bellincampi L; Melino G; Avigliano L
Ascorbic acid recycling in N-myc amplified human neuroblastoma cells.
Anticancer research 1998;18(2A):819-22.
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1998: Melino G; De Laurenzi V; Catani M V; Terrinoni A; Ciani B; Candi E; Marekov L; Steinert P M
The cornified envelope: a model of cell death in the skin.
Results and problems in cell differentiation 1998;24():175-212.
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1997: Lovat P E; Irving H; Annicchiarico-Petruzzelli M; Bernassola F; Malcolm A J; Pearson A D; Melino G; Redfern C P
Retinoids in neuroblastoma therapy: distinct biological properties of 9-cis- and all-trans-retinoic acid.
European journal of cancer (Oxford, England : 1990) 1997;33(12):2075-80.
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1997: Melino G; Draoui M; Bellincampi L; Bernassola F; Bernardini S; Piacentini M; Reichert U; Cohen P
Retinoic acid receptors alpha and gamma mediate the induction of "tissue" transglutaminase activity and apoptosis in human neuroblastoma cells.
Experimental cell research 1997;235(1):55-61.
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1997: Maccarrone M; Catani M V; Agrò A F; Melino G
Involvement of 5-lipoxygenase in programmed cell death of cancer cells.
Cell death and differentiation 1997;4(5):396-402.
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1997: Melino G; Bernassola F; Knight R A; Corasaniti M T; Nistico G; Finazzi-Agro A
S-nitrosylation regulates apoptosis.
Nature 1997;388(6641):432-3.
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1997: Bernardini S; Melino G; Saura F; Annicchiarico-Petruzzelli M; Motti C; Cortese C; Federici G
Expression of co-factors (SMRT and Trip-1) for retinoic acid receptors in human neuroectodermal cell lines.
Biochemical and biophysical research communications 1997;234(1):278-82.
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1997: Lovat P E; Irving H; Annicchiarico-Petruzzelli M; Bernassola F; Malcolm A J; Pearson A D; Melino G; Redfern C P
Apoptosis of N-type neuroblastoma cells after differentiation with 9-cis-retinoic acid and subsequent washout.
Journal of the National Cancer Institute 1997;89(6):446-52.
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1997: Candi E; Knight R A; Spinedi A; Guerrieri P; Melino G
A possible growth factor role of IL-6 in neuroectodermal tumours.
Journal of neuro-oncology 1997;31(1-2):115-22.
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1997: Draoui M; Bellincampi L; Hospital V; Cadel S; Foulon T; Prat A; Barré N; Reichert U; Melino G; Cohen P
Expression and retinoid modulation of N-arginine dibasic convertase and an aminopeptidase-B in human neuroblastoma cell lines.
Journal of neuro-oncology 1997;31(1-2):99-106.
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1997: Melino G; Thiele C J; Knight R A; Piacentini M
Retinoids and the control of growth/death decisions in human neuroblastoma cell lines.
Journal of neuro-oncology 1997;31(1-2):65-83.
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1996: Piacentini M; Piredda L; Starace D T; Annicchiarico-Petruzzelli M; Mattei M; Oliverio S; Farrace M G; Melino G
Differential growth of N- and S-type human neuroblastoma cells xenografted into scid mice. correlation with apoptosis.
The Journal of pathology 1996;180(4):415-22.
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1996: Tarcsa E; Marekov L N; Mei G; Melino G; Lee S C; Steinert P M
Protein unfolding by peptidylarginine deiminase. Substrate specificity and structural relationships of the natural substrates trichohyalin and filaggrin.
The Journal of biological chemistry 1996;271(48):30709-16.
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1996: Maccarrone M; Nieuwenhuizen W E; Dullens H F; Catani M V; Melino G; Veldink G A; Vliegenthart J F; Finazzo Agrò A
Membrane modifications in human erythroleukemia K562 cells during induction of programmed cell death by transforming growth factor beta 1 or cisplatin.
European journal of biochemistry / FEBS 1996;241(1):297-302.
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1996: Demartis A; Bernassola F; Savino R; Melino G; Ciliberto G
Interleukin 6 receptor superantagonists are potent inducers of human multiple myeloma cell death.
Cancer research 1996;56(18):4213-8.
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1996: Melino G; Draoui M; Bernardini S; Bellincampi L; Reichert U; Cohen P
Regulation by retinoic acid of insulin-degrading enzyme and of a related endoprotease in human neuroblastoma cell lines.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1996;7(6):787-96.
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1995: Candi E; Melino G; Mei G; Tarcsa E; Chung S I; Marekov L N; Steinert P M
Biochemical, structural, and transglutaminase substrate properties of human loricrin, the major epidermal cornified cell envelope protein.
The Journal of biological chemistry 1995;270(44):26382-90.
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1995: Candi E; Melino G; De Laurenzi V; Piacentini M; Guerrieri P; Spinedi A; Knight R A
Tamoxifen and somatostatin affect tumours by inducing apoptosis.
Cancer letters 1995;96(1):141-5.
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1995: De Laurenzi V; Melino G; Savini I; Annicchiarico-Petruzzelli M; Finazzi-Agrò A; Avigliano L
Cell death by oxidative stress and ascorbic acid regeneration in human neuroectodermal cell lines.
European journal of cancer (Oxford, England : 1990) 1995;31A(4):463-6.
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1994: Melino G; Annicchiarico-Petruzzelli M; Piredda L; Candi E; Gentile V; Davies P J; Piacentini M
Tissue transglutaminase and apoptosis: sense and antisense transfection studies with human neuroblastoma cells.
Molecular and cellular biology 1994;14(10):6584-96.
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1994: Bernardini S; Cianfarani S; Spagnoli A; Annicchiarico-Petruzzelli M; Melino G; Massoud R; Boscherini B; Finazzi-Agró A; Rosenfeld R G; Federici G
Expression and down-regulation by retinoic acid of IGF binding protein-2 and -4 in medium from human neuroblastoma cells.
Journal of neuroendocrinology 1994;6(4):409-13.
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1994: Piacentini M; Melino G
Role of tissue transglutaminase in neuroblastoma cells undergoing apoptosis.
Progress in clinical and biological research 1994;385():123-9.
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1993: De Laurenzi V; Melino G; Knight R A; Pierotti A R; Cohen P
Modulation of POMC expression in human neuroectodermal cells.
Biochemical and biophysical research communications 1993;197(3):1402-9.
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1993: Bagetta G; Corasaniti M T; Melino G; Paoletti A M; Finazzi-Agrò A; Nisticò G
Lithium and tacrine increase the expression of nitric oxide synthase mRNA in the hippocampus of rat.
Biochemical and biophysical research communications 1993;197(3):1132-9.
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1993: Piacentini M; Fesus L; Melino G
Multiple cell cycle access to the apoptotic death programme in human neuroblastoma cells.
FEBS letters 1993;320(2):150-4.
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1993: Melino G; Stephanou A; Annicchiarico-Petruzzelli M; Knight R A; Finazzi-Agró A; Lightman S L
Modulation of IGF-2 expression during growth and differentiation of human neuroblastoma cells: retinoic acid may induce IGF-2.
Neuroscience letters 1993;151(2):187-91.
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1993: Melino G; Knight R A; Thiele C J
New insight on the biology of neuroectodermal tumors. Workshop report from the University of Rome Tor Vergata and the IDI-IRCCS on the genetics and control of growth, differentiation, and programmed cell death.
Cancer research 1993;53(4):926-8.
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1992: Corasaniti M T; Tartaglia R L; Melino G; Nisticò G; Finazzi-Agrò A
Evidence that CHP100 neuroblastoma cell death induced by N-methyl-D-aspartate involves L-arginine-nitric oxide pathway activation.
Neuroscience letters 1992;147(2):221-3.
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1992: Vernole P; Tedeschi B; Melino G; Pianca C; Nicoletti B
Enhanced chromosomal fragility in neuroblastoma: correlation with poor prognosis.
Anticancer research 1992;12(5):1419-21.
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1992: Melino G; Stephanou A; Annicchiarico-Petruzzelli M; Finazzi-Agró A; Knight R A; Lightman S L
IGF-II mRNA expression in LI human glioblastoma cell line parallels cell growth.
Neuroscience letters 1992;144(1-2):25-8.
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1992: Melino G; Vernole P; Annicchiarico-Petruzzelli M; Stephanou A; Colantoni A; Knight R A; Spagnoli L G; Finazzi-Agro A
An inducible cell line (Natasha), from a neuroblastoma patient with circulating HSR-positive blasts, expressing neurohormones.
Anticancer research 1992;12(4):1199-206.
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1991: Piacentini M; Fesus L; Farrace M G; Ghibelli L; Piredda L; Melino G
The expression of "tissue" transglutaminase in two human cancer cell lines is related with the programmed cell death (apoptosis).
European journal of cell biology 1991;54(2):246-54.
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1991: Melino G; Piacentini M; Patel K; Annicchiarico-Petruzzelli M; Piredda L; Kemshead J T
Retinoic acid and alpha-difluoromethylornithine induce different expression of neural-specific cell adhesion molecules in differentiating neuroblastoma cells.
Progress in clinical and biological research 1991;366():283-91.
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1990: Melino G; Savini I; Guerrieri P; Finazzi-Agrò A
Redox buffering ability of lymphoid cells evaluated by the oxidation of 2',7'-dichlorofluorescin.
Free radical research communications 1990;11(4-5):213-21.
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1989: Melino G; Concato C; Menichella D; Vescia N; Mastroeni I; Pestalozza S; Buonavoglia C; Caliò R
Lymphocyte proliferative response to rabies virus antigen.
Microbiologica 1989;12(3):215-23.
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1989: Melino G; Savini I; Guerrieri P; Finazzi-Agrò A
Peroxidative activity in lymphoid cells evaluated by 2'-7'-dichlorofluorescein diacetate.
The Italian journal of biochemistry 1989;38(4):256A-258A.
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1988: Melino G; Farrace M G; Ceru' M P; Piacentini M
Correlation between transglutaminase activity and polyamine levels in human neuroblastoma cells. Effect of retinoic acid and alpha-difluoromethylornithine.
Experimental cell research 1988;179(2):429-45.
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1988: Vernole P; Concato C; Pianca C; Nicoletti B; Melino G
Association of cytogenetic abnormalities in a neuroblastoma and fragile sites expression.
British journal of cancer 1988;58(3):287-91.
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