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Synthia Mellon
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15
Compagnone, Nathalie
10
Bair, Susanna
10
Miller, Walter
10
Zhang, P
6
Vigne, Jean-Louis
5
Griffin, Lisa
4
Wolkowitz, Owen
3
Ganten, Detlev
3
Epel, Elissa
3
Deschepper, Christian
2
Weiner, Richard
2
Bulfone, Alessandro
2
Givens, CR
2
Mesiano, S
2
Jaffe, Robert
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All Publications
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2009: Vinogradov Sophia; Fisher Melissa; Holland Christine; Shelly Wendy; Wolkowitz Owen; Mellon Synthia H
Is serum brain-derived neurotrophic factor a biomarker for cognitive enhancement in schizophrenia?
Biological psychiatry 2009;66(6):549-53.
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2009: Dhabhar Firdaus S; Burke Heather M; Epel Elissa S; Mellon Synthia H; Rosser Rebecca; Reus Victor I; Wolkowitz Owen M
Low serum IL-10 concentrations and loss of regulatory association between IL-6 and IL-10 in adults with major depression.
Journal of psychiatric research 2009;43(11):962-9.
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2009: Shi Yimin; Schonemann Marcus D; Mellon Synthia H
Regulation of P450c17 expression in the early embryo depends on GATA factors.
Endocrinology 2009;150(2):946-56.
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2009: Maninger Nicole; Wolkowitz Owen M; Reus Victor I; Epel Elissa S; Mellon Synthia H
Neurobiological and neuropsychiatric effects of dehydroepiandrosterone (DHEA) and DHEA sulfate (DHEAS).
Frontiers in neuroendocrinology 2009;30(1):65-91.
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2008: Mellon Synthia H; Gong Wenhui; Schonemann Marcus D
Endogenous and synthetic neurosteroids in treatment of Niemann-Pick Type C disease.
Brain research reviews 2008;57(2):410-20.
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2008: Wolkowitz Owen M; Epel Elissa S; Mellon Synthia
When blue turns to grey: do stress and depression accelerate cell aging?
The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry 2008;9(1):2-5.
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2007: Mellon Synthia H
Neurosteroid regulation of central nervous system development.
Pharmacology & therapeutics 2007;116(1):107-24.
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2007: Mellon Synthia H; Bair Susanna R; Depoix Christophe; Vigne Jean-Louis; Hecht Norman B; Brake Paul B
Translin coactivates steroidogenic factor-1-stimulated transcription.
Molecular endocrinology (Baltimore, Md.) 2007;21(1):89-105.
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2006: Langmade S Joshua; Gale Sarah E; Frolov Andrey; Mohri Ikuko; Suzuki Kinuko; Mellon Synthia H; Walkley Steven U; Covey Douglas F; Schaffer Jean E; Ory Daniel S
Pregnane X receptor (PXR) activation: a mechanism for neuroprotection in a mouse model of Niemann-Pick C disease.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(37):13807-12.
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2005: Brake Paul B; Bair Susanna R; Mellon Synthia H
DNA sequence-dependent regulation of SF-1-mediated transcription.
DNA and cell biology 2005;24(3):148-60.
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2004: Mellon Synthia; Gong Wenhui; Griffin Lisa D
Niemann pick type C disease as a model for defects in neurosteroidogenesis.
Endocrine research 2004;30(4):727-35.
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2004: Griffin Lisa D; Gong Wenhui; Verot Lucie; Mellon Synthia H
Niemann-Pick type C disease involves disrupted neurosteroidogenesis and responds to allopregnanolone.
Nature medicine 2004;10(7):704-11.
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2004: Bair Susanna R; Mellon Synthia H
Deletion of the mouse P450c17 gene causes early embryonic lethality.
Molecular and cellular biology 2004;24(12):5383-90.
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2004: Komesaroff Paul A; Bach Mark A; Danoff Ann; Grumbach Melvin M; Kaplan Selna; Lakoski Joan M; Leitman Dale; Mellon Synthia; Underwood Louis E; Leupen Sarah;
The Endocrine Society Ethics Advisory Committee: ethical aspects of conflicts of interests, October 2003.
Endocrinology 2004;145(6):3032-41.
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2004: Hong Cheol Yi; Park Jin Hee; Ahn Ryun Seop; Im Suhn Young; Choi Hueng-Sik; Soh Jaemog; Mellon Synthia H; Lee Keesook
Molecular mechanism of suppression of testicular steroidogenesis by proinflammatory cytokine tumor necrosis factor alpha.
Molecular and cellular biology 2004;24(7):2593-604.
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2004: Hammer Fabian; Compagnone Nathalie A; Vigne Jean-Louis; Bair Susanna R; Mellon Synthia H
Transcriptional regulation of P450scc gene expression in the embryonic rodent nervous system.
Endocrinology 2004;145(2):901-12.
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2003: Pandey Amit V; Mellon Synthia H; Miller Walter L
Protein phosphatase 2A and phosphoprotein SET regulate androgen production by P450c17.
The Journal of biological chemistry 2003;278(5):2837-44.
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2002: Mellon Synthia H; Griffin Lisa D
Synthesis, regulation, and function of neurosteroids.
Endocrine research 2002;28(4):463.
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2002: Zhang Martin Y H; Wang Xuemei; Wang Jonathan T; Compagnone Nathalie A; Mellon Synthia H; Olson Jean L; Tenenhouse Harriet S; Miller Walter L; Portale Anthony A
Dietary phosphorus transcriptionally regulates 25-hydroxyvitamin D-1alpha-hydroxylase gene expression in the proximal renal tubule.
Endocrinology 2002;143(2):587-95.
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2002: Mellon Synthia H; Griffin Lisa D
Neurosteroids: biochemistry and clinical significance.
Trends in endocrinology and metabolism: TEM 2002;13(1):35-43.
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2001: Mellon S H; Griffin L D; Compagnone N A
Biosynthesis and action of neurosteroids.
Brain research. Brain research reviews 2001;37(1-3):3-12.
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2001: Griffin L D; Mellon S H
Biosynthesis of the neurosteroid 3 alpha-hydroxy-4-pregnen-20-one (3 alpha hp), a specific inhibitor of FSH release.
Endocrinology 2001;142(11):4617-22.
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2001: Zhang P; Compagnone N A; Fiore C; Vigne J L; Culp P; Musci T J; Mellon S H
Developmental gonadal expression of the transcription factor SET and its target gene, P450c17 (17alpha-hydroxylase/c17,20 lyase).
DNA and cell biology 2001;20(10):613-24.
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2001: Fujii E; Mellon S H
Regulation of uterine gamma-aminobutyric acid(A) receptor subunit expression throughout pregnancy.
Endocrinology 2001;142(5):1770-7.
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2001: Griffin L D; Conrad S C; Mellon S H
Current perspectives on the role of neurosteroids in PMS and depression.
International review of neurobiology 2001;46():479-92.
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2001: Mellon S H; Vaudry H
Biosynthesis of neurosteroids and regulation of their synthesis.
International review of neurobiology 2001;46():33-78.
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2001: Chanoine J P; Compagnone N A; Wong A C; Mellon S H
Modulation of steroidogenesis by selenium in a novel adrenal cell line developed using targeted tumorigenesis.
BioFactors (Oxford, England) 2001;14(1-4):229-38.
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2000: Adi S; Cheng Z Q; Zhang P L; Wu N Y; Mellon S H; Rosenthal S M
Opposing early inhibitory and late stimulatory effects of insulin-like growth factor-I on myogenin gene transcription.
Journal of cellular biochemistry 2000;78(4):617-26.
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2000: Compagnone N A; Zhang P; Vigne J L; Mellon S H
Novel role for the nuclear phosphoprotein SET in transcriptional activation of P450c17 and initiation of neurosteroidogenesis.
Molecular endocrinology (Baltimore, Md.) 2000;14(6):875-88.
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2000: Compagnone N A; Mellon S H
Neurosteroids: biosynthesis and function of these novel neuromodulators.
Frontiers in neuroendocrinology 2000;21(1):1-56.
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2000: Ingraham H A; Hirokawa Y; Roberts L M; Mellon S H; McGee E; Nachtigal M W; Visser J A
Autocrine and paracrine Müllerian inhibiting substance hormone signaling in reproduction.
Recent progress in hormone research 2000;55():53-67; discussion 67-8.
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1999: Griffin L D; Mellon S H
Selective serotonin reuptake inhibitors directly alter activity of neurosteroidogenic enzymes.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(23):13512-7.
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1999: Zhang P; Hammer F; Bair S; Wang J; Reeves W H; Mellon S H
Ku autoimmune antigen is involved in placental regulation of rat P450c17 gene transcription.
DNA and cell biology 1999;18(3):197-208.
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1998: Mellon S H; Compagnone N A; Zhang P
Orphan receptors, proto-oncogenes and other nuclear factors regulate P450C17 gene transcription.
Endocrine research 1998;24(3-4):505-13.
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1998: Mellon S H; Bair S R
25-Hydroxycholesterol is not a ligand for the orphan nuclear receptor steroidogenic factor-1 (SF-1).
Endocrinology 1998;139(6):3026-9.
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1998: Compagnone N A; Mellon S H
Dehydroepiandrosterone: a potential signalling molecule for neocortical organization during development.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(8):4678-83.
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1998: Zhang P; Vigne J L; Mellon S H
Polyribonucleotide phosphorylase is a double-stranded DNA-binding protein.
DNA and cell biology 1998;17(2):169-75.
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1997: Compagnone N A; Salido E; Shapiro L J; Mellon S H
Expression of steroid sulfatase during embryogenesis.
Endocrinology 1997;138(11):4768-73.
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1997: Zhang P; Mellon S H
Multiple orphan nuclear receptors converge to regulate rat P450c17 gene transcription: novel mechanisms for orphan nuclear receptor action.
Molecular endocrinology (Baltimore, Md.) 1997;11(7):891-904.
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1997: Compagnone N A; Bair S R; Mellon S H
Characterization of adrenocortical cell lines produced by genetically targeted tumorigenesis in transgenic mice.
Steroids 1997;62(2):238-43.
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1997: Mellon S H; Zhang P
The testis and the adrenal are (transcriptionally) the same.
Steroids 1997;62(1):46-52.
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1996: Scheumann G F; Heitmann P; Teebken O E; Mössinger E; Mellon S H; Pichlmayr R
Enzymatic properties of transplanted glomerulosa cells.
World journal of surgery 1996;20(7):933-8; discussion 938-9.
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1996: Yamamoto T; Chapman B M; Johnson D C; Givens C R; Mellon S H; Soares M J
Cytochrome P450 17 alpha-hydroxylase gene expression in differentiating rat trophoblast cells.
The Journal of endocrinology 1996;150(1):161-8.
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1996: Zhang P; Han X G; Mellon S H; Hall P F
Expression of the gene for cytochrome P-450 17 alpha-hydroxylase/C17-20 lyase (CYP17) in porcine Leydig cells: identification of a DNA sequence that mediates cAMP response.
Biochimica et biophysica acta 1996;1307(1):73-82.
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1996: Zhang P; Mellon S H
The orphan nuclear receptor steroidogenic factor-1 regulates the cyclic adenosine 3',5'-monophosphate-mediated transcriptional activation of rat cytochrome P450c17 (17 alpha-hydroxylase/c17-20 lyase).
Molecular endocrinology (Baltimore, Md.) 1996;10(2):147-58.
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1995: Zhang P; Rodriguez H; Mellon S H
Transcriptional regulation of P450scc gene expression in neural and steroidogenic cells: implications for regulation of neurosteroidogenesis.
Molecular endocrinology (Baltimore, Md.) 1995;9(11):1571-82.
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1995: Compagnone N A; Bulfone A; Rubenstein J L; Mellon S H
Steroidogenic enzyme P450c17 is expressed in the embryonic central nervous system.
Endocrinology 1995;136(11):5212-23.
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1995: Allen R G; Carey C; Parker J D; Mortrud M T; Mellon S H; Low M J
Targeted ablation of pituitary pre-proopiomelanocortin cells by herpes simplex virus-1 thymidine kinase differentially regulates mRNAs encoding the adrenocorticotropin receptor and aldosterone synthase in the mouse adrenal gland.
Molecular endocrinology (Baltimore, Md.) 1995;9(8):1005-16.
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1995: Cover C M; Wang J M; St Lezin E; Kurtz T W; Mellon S H
Molecular variants in the P450c11AS gene as determinants of aldosterone synthase activity in the Dahl rat model of hypertension.
The Journal of biological chemistry 1995;270(28):16555-60.
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1995: Compagnone N A; Bulfone A; Rubenstein J L; Mellon S H
Expression of the steroidogenic enzyme P450scc in the central and peripheral nervous systems during rodent embryogenesis.
Endocrinology 1995;136(6):2689-96.
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1995: Djavidani B; Sander M; Kreutz R; Zeh K; Bader M; Mellon S H; Vecsei P; Peters J; Ganten D
Chronic dexamethasone treatment suppresses hypertension development in the transgenic rat TGR(mREN2)27.
Journal of hypertension 1995;13(6):637-45.
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1995: Fardella C E; Rodriguez H; Hum D W; Mellon S H; Miller W L
Artificial mutations in P450c11AS (aldosterone synthase) can increase enzymatic activity: a model for low-renin hypertension?
The Journal of clinical endocrinology and metabolism 1995;80(3):1040-3.
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1995: Saenger P; Klonari Z; Black S M; Compagnone N; Mellon S H; Fleischer A; Abrams C A; Shackelton C H; Miller W L
Prenatal diagnosis of congenital lipoid adrenal hyperplasia.
The Journal of clinical endocrinology and metabolism 1995;80(1):200-5.
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1995: Mellon S H; Bair S R; Monis H
P450c11B3 mRNA, transcribed from a third P450c11 gene, is expressed in a tissue-specific, developmentally, and hormonally regulated fashion in the rodent adrenal and encodes a protein with both 11-hydroxylase and 18-hydroxylase activities.
The Journal of biological chemistry 1995;270(4):1643-9.
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1995: Mellon S H; Compagnone N; Sander M; Cover C; Ganten D; Djavidani B
Rodent models for studying steroids and hypertension: from fetal development to cells in culture.
Steroids 1995;60(1):59-64.
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1994: Givens C R; Zhang P; Bair S R; Mellon S H
Transcriptional regulation of rat cytochrome P450c17 expression in mouse Leydig MA-10 and adrenal Y-1 cells: identification of a single protein that mediates both basal and cAMP-induced activities.
DNA and cell biology 1994;13(11):1087-98.
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1994: Mellon S H
Neurosteroids: biochemistry, modes of action, and clinical relevance.
The Journal of clinical endocrinology and metabolism 1994;78(5):1003-8.
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1994: Sander M; Ganten D; Mellon S H
Role of adrenal renin in the regulation of adrenal steroidogenesis by corticotropin.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(1):148-52.
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1994: Mellon S H; Miller W L; Bair S R; Moore C C; Vigne J L; Weiner R I
Steroidogenic adrenocortical cell lines produced by genetically targeted tumorigenesis in transgenic mice.
Molecular endocrinology (Baltimore, Md.) 1994;8(1):97-108.
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1993: Mellon S H; Deschepper C F
Neurosteroid biosynthesis: genes for adrenal steroidogenic enzymes are expressed in the brain.
Brain research 1993;629(2):283-92.
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1993: Moore C C; Mellon S H; Murai J; Siiteri P K; Miller W L
Structure and function of the hepatic form of 11 beta-hydroxysteroid dehydrogenase in the squirrel monkey, an animal model of glucocorticoid resistance.
Endocrinology 1993;133(1):368-75.
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1993: Bristow J; Tee M K; Gitelman S E; Mellon S H; Miller W L
Tenascin-X: a novel extracellular matrix protein encoded by the human XB gene overlapping P450c21B.
The Journal of cell biology 1993;122(1):265-78.
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1993: Mesiano S; Mellon S H; Jaffe R B
Mitogenic action, regulation, and localization of insulin-like growth factors in the human fetal adrenal gland.
The Journal of clinical endocrinology and metabolism 1993;76(4):968-76.
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1991: Malee M P; Mellon S H
Zone-specific regulation of two messenger RNAs for P450c11 in the adrenals of pregnant and nonpregnant rats.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(11):4731-5.
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1991: Mellon S H; Kushner J A; Vaisse C
Expression and regulation of adrenodoxin and P450scc mRNA in rodent tissues.
DNA and cell biology 1991;10(5):339-47.
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1991: Mesiano S; Mellon S H; Gospodarowicz D; Di Blasio A M; Jaffe R B
Basic fibroblast growth factor expression is regulated by corticotropin in the human fetal adrenal: a model for adrenal growth regulation.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(12):5428-32.
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1991: Mellon S H; Shively J E; Miller W L
Human proopiomelanocortin-(79-96), a proposed androgen stimulatory hormone, does not affect steroidogenesis in cultured human fetal adrenal cells.
The Journal of clinical endocrinology and metabolism 1991;72(1):19-22.
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1990: Brentano S T; Picado-Leonard J; Mellon S H; Moore C C; Miller W L
Tissue-specific, cyclic adenosine 3',5'-monophosphate-induced, and phorbol ester-repressed transcription from the human P450c17 promoter in mouse cells.
Molecular endocrinology (Baltimore, Md.) 1990;4(12):1972-9.
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1990: Elias K A; Weiner R I; Mellon S H
Effect of extracellular matrix on prolactin secretion and mRNA accumulation in GH3 cells.
DNA and cell biology 1990;9(5):369-75.
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1989: Mellon S H; Miller W L
Extraadrenal steroid 21-hydroxylation is not mediated by P450c21.
The Journal of clinical investigation 1989;84(5):1497-502.
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1989: Mellon S H; Vaisse C
cAMP regulates P450scc gene expression by a cycloheximide-insensitive mechanism in cultured mouse Leydig MA-10 cells.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(20):7775-9.
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1988: Mellon S H; Baxter J D; Gutierrez-Hartmann A
Cell-specific expression of transfected brain identifier repetitive DNAs.
Nucleic acids research 1988;16(9):3963-76.
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1987: Lightman A; Deschepper C F; Mellon S H; Ganong W F; Naftolin F
In situ hybridization identifies renin mRNA in the rat corpus luteum.
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 1987;1(3):227-33.
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1987: West B L; Catanzaro D F; Mellon S H; Cattini P A; Baxter J D; Reudelhuber T L
Interaction of a tissue-specific factor with an essential rat growth hormone gene promoter element.
Molecular and cellular biology 1987;7(3):1193-7.
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1986: Deschepper C F; Mellon S H; Cumin F; Baxter J D; Ganong W F
Analysis by immunocytochemistry and in situ hybridization of renin and its mRNA in kidney, testis, adrenal, and pituitary of the rat.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(19):7552-6.
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1985: Chung B C; Matteson K J; Morin J E; Mellon S H; Miller W L
An approach to the molecular biology of congenital adrenal hyperplasia.
Annals of the New York Academy of Sciences 1985;458():238-51.
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1984: Karin M; Eberhardt N L; Mellon S H; Malich N; Richards R I; Slater E P; Barta A; Martial J A; Baxter J D; Cathala G
Expression and hormonal regulation of the rat growth hormone gene in transfected mouse L cells.
DNA (Mary Ann Liebert, Inc.) 1984;3(2):147-55.
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1982: Spindler S R; Mellon S H; Baxter J D
Growth hormone gene transcription is regulated by thyroid and glucocorticoid hormones in cultured rat pituitary tumor cells.
The Journal of biological chemistry 1982;257(19):11627-32.
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