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Shlomo Melmed

Research Profile

Disorders

Anatomy

Pituitary Gland

Chemicals & Drugs

Living Beings

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Rats

Physiology

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Mark L Hartman; David L Kleinberg; Shlomo Melmed; Leslie L Robison; Whitney W Woodmansee; Rong Xu; Alan G Zimmermann; John J Chipman; Brenda J Crowe; Gordon B Cutler; Eva Marie Erfurth
Prospective safety surveillance of GH-deficient adults: comparison of GH-treated vs untreated patients.
Vera Chesnokova; Vladimir Ljubimov; Adam Mamelak; Serguei Bannykh; Anat Ben-Shlomo; Yuji Tani; Kolja Wawrowsky; Svetlana Zonis; Shlomo Melmed
Clusterin and FOXL2 act concordantly to regulate pituitary gonadotroph adenoma growth.
Anna Gruszka; Michael D Culler; Shlomo Melmed
Somatostatin analogs and chimeric somatostatin-dopamine molecules differentially regulate human growth hormone and prolactin gene expression and secretion in vitro.

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2013: Mark L Hartman; David L Kleinberg; Shlomo Melmed; Leslie L Robison; Whitney W Woodmansee; Rong Xu; Alan G Zimmermann; John J Chipman; Brenda J Crowe; Gordon B Cutler; Eva Marie Erfurth
Prospective safety surveillance of GH-deficient adults: comparison of GH-treated vs untreated patients.
The Journal of clinical endocrinology and metabolism 2013;98(3):980-8.
2012: Vera Chesnokova; Vladimir Ljubimov; Adam Mamelak; Serguei Bannykh; Anat Ben-Shlomo; Yuji Tani; Kolja Wawrowsky; Svetlana Zonis; Shlomo Melmed
Clusterin and FOXL2 act concordantly to regulate pituitary gonadotroph adenoma growth.
Molecular endocrinology (Baltimore, Md.) 2012;26(12):2092-103.
2012: Anna Gruszka; Michael D Culler; Shlomo Melmed
Somatostatin analogs and chimeric somatostatin-dopamine molecules differentially regulate human growth hormone and prolactin gene expression and secretion in vitro.
Molecular and cellular endocrinology 2012;362(1-2):104-9.
2012: Yoel Toledano; Kolja Wawrowsky; Svetlana Zonis; Vera Chesnokova; Song-Guang Ren; Shlomo Melmed
Estradiol partially recapitulates murine pituitary cell cycle response to pregnancy.
Endocrinology 2012;153(10):5011-22.
2012: Odelia Cooper; Shlomo Melmed
Subclinical hyperfunctioning pituitary adenomas: the silent tumors.
Best practice & research. Clinical endocrinology & metabolism 2012;26(4):447-60.
2012: Yunguang Tong; Yun Zheng; Jin Zhou; H Phillip Koeffler; Nelson M Oyesiku; Shlomo Melmed
Genomic characterization of human and rat prolactinomas.
Endocrinology 2012;153(8):3679-91.
2011: Odelia Cooper; Hidenori Fukuoka; Mark I Greene; George Vlotides; Shlomo Melmed
Expression and function of ErbB receptors and ligands in the pituitary.
Endocrine-related cancer 2011;18(6):R197-211.
2011: Pouyan Famini; Marcel M Maya; Shlomo Melmed
Pituitary magnetic resonance imaging for sellar and parasellar masses: ten-year experience in 2598 patients.
The Journal of clinical endocrinology and metabolism 2011;96(6):1633-41.
2011: Ning-Ai Liu; Hong Jiang; Anat Ben-Shlomo; Kolja Wawrowsky; Xue-Mo Fan; Shuo Lin; Shlomo Melmed
Targeting zebrafish and murine pituitary corticotroph tumors with a cyclin-dependent kinase (CDK) inhibitor.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(20):8414-9.
2011: Shlomo Melmed
Pathogenesis of pituitary tumors.
Nature reviews. Endocrinology 2011;7(5):257-66.
2011: Yunguang Tong; Kolja Wawrowsky; Weijiang Zhao; Cuiqi Zhou; Shlomo Melmed
PTTG1 attenuates drug-induced cellular senescence.
PloS one 2011;6(8):e23754.
2011: Vera Chesnokova; Svetlana Zonis; Cuiqi Zhou; Anat Ben-Shlomo; Kolja Wawrowsky; Yoel Toledano; Yunguang Tong; Kalman Kovacs; Bernd Scheithauer; Shlomo Melmed
Lineage-specific restraint of pituitary gonadotroph cell adenoma growth.
PloS one 2011;6(3):e17924.
2011: Yesenia Ríos; Shlomo Melmed; Shuo Lin; Ning-Ai Liu
Zebrafish usp39 mutation leads to rb1 mRNA splicing defect and pituitary lineage expansion.
PLoS genetics 2011;7(1):e1001271.
2011: Hidenori Fukuoka; Odelia Cooper; Jun Mizutani; Yunguang Tong; Song-Guang Ren; Serguei Bannykh; Shlomo Melmed
HER2/ErbB2 receptor signaling in rat and human prolactinoma cells: strategy for targeted prolactinoma therapy.
Molecular endocrinology (Baltimore, Md.) 2011;25(1):92-103.
2010: Anat Ben-Shlomo; Shlomo Melmed
Pituitary somatostatin receptor signaling.
Trends in endocrinology and metabolism: TEM 2010;21(3):123-33.
2010: Vera Chesnokova; Svetlana Zonis; Anat Ben-Shlomo; Kolja Wawrowsky; Shlomo Melmed
Molecular mechanisms of pituitary adenoma senescence.
Frontiers of hormone research 2010;38():7-14.
2010: Run Yu; Shlomo Melmed
Pathogenesis of pituitary tumors.
Progress in brain research 2010;182():207-27.
2010: Shlomo Melmed; David Cook; Jochen Schopohl; Miklos I Goth; Karen S L Lam; Josef Marek
Rapid and sustained reduction of serum growth hormone and insulin-like growth factor-1 in patients with acromegaly receiving lanreotide Autogel therapy: a randomized, placebo-controlled, multicenter study with a 52 week open extension.
Pituitary 2010;13(1):18-28.
2009: Shlomo Melmed
Acromegaly pathogenesis and treatment.
The Journal of clinical investigation 2009;119(11):3189-202.
2009: Anat Ben-Shlomo; Herbert Schmid; Kolja Wawrowsky; Oxana Pichurin; Erika Hubina; Vera Chesnokova; Ning-Ai Liu; Michael D Culler; Shlomo Melmed
Differential ligand-mediated pituitary somatostatin receptor subtype signaling: implications for corticotroph tumor therapy.
The Journal of clinical endocrinology and metabolism 2009;94(11):4342-50.
2009: George Vlotides; Yen-Hao Chen; Tamar Eigler; Song-Guang Ren; Shlomo Melmed
Fibroblast growth factor-2 autofeedback regulation in pituitary folliculostellate TtT/GF cells.
Endocrinology 2009;150(7):3252-8.
2009: George Vlotides; Odelia Cooper; Yen-Hao Chen; Song-Guang Ren; Yona Greenman; Shlomo Melmed
Heregulin regulates prolactinoma gene expression.
Cancer research 2009;69(10):4209-16.
2009: Shlomo Melmed; A Colao; Ariel L Barkan; M Molitch; A B Grossman; D Kleinberg; David R Clemmons; P Chanson; E Laws; J Schlechte; M L Vance; K Ho; A Giustina
Guidelines for acromegaly management: an update.
The Journal of clinical endocrinology and metabolism 2009;94(5):1509-17.
2009: Vera Chesnokova; Shlomo Melmed
Pituitary tumour-transforming gene (PTTG) and pituitary senescence.
Hormone research 2009;71 Suppl 2():82-7.
2009: Anat Ben-Shlomo; Cuiqi Zhou; Oxana Pichurin; Vera Chesnokova; Ning-Ai Liu; Michael D Culler; Shlomo Melmed
Constitutive somatostatin receptor activity determines tonic pituitary cell response.
Molecular endocrinology (Baltimore, Md.) 2009;23(3):337-48.
2009: John D Carmichael; Vivien Bonert; James M Mirocha; Shlomo Melmed
The utility of oral glucose tolerance testing for diagnosis and assessment of treatment outcomes in 166 patients with acromegaly.
The Journal of clinical endocrinology and metabolism 2009;94(2):523-7.
2008: Vera Chesnokova; Svetlana Zonis; Kalman Kovacs; Anat Ben-Shlomo; Kolja Wawrowsky; Serguei Bannykh; Shlomo Melmed
p21(Cip1) restrains pituitary tumor growth.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(45):17498-503.
2008: Y Tong; Anat Ben-Shlomo; C Zhou; K Wawrowsky; Shlomo Melmed
Pituitary tumor transforming gene 1 regulates Aurora kinase A activity.
Oncogene 2008;27(49):6385-95.
2008: Vivien Bonert; Laurence Kennedy; Stephan Petersenn; Ariel L Barkan; John Carmichael; Shlomo Melmed
Lipodystrophy in patients with acromegaly receiving pegvisomant.
The Journal of clinical endocrinology and metabolism 2008;93(9):3515-8.
2008: Cuiqi Zhou; Yunguang Tong; Kolja Wawrowsky; Serguei Bannykh; Ines Donangelo; Shlomo Melmed
Oct-1 induces pituitary tumor transforming gene expression in endocrine tumors.
Endocrine-related cancer 2008;15(3):817-31.
2008: George Vlotides; Emily Siegel; Ines Donangelo; Shiri Gutman; Song-Guang Ren; Shlomo Melmed
Rat prolactinoma cell growth regulation by epidermal growth factor receptor ligands.
Cancer research 2008;68(15):6377-86.
2008: Robert D Murray; Shlomo Melmed
A critical analysis of clinically available somatostatin analog formulations for therapy of acromegaly.
The Journal of clinical endocrinology and metabolism 2008;93(8):2957-68.
2008: Ning-Ai Liu; Meina Ren; Jianbo Song; Yesenia Ríos; Kolja Wawrowsky; Anat Ben-Shlomo; Shuo Lin; Shlomo Melmed
In vivo time-lapse imaging delineates the zebrafish pituitary proopiomelanocortin lineage boundary regulated by FGF3 signal.
Developmental biology 2008;319(2):192-200.
2008: Anat Ben-Shlomo; Shlomo Melmed
Somatostatin agonists for treatment of acromegaly.
Molecular and cellular endocrinology 2008;286(1-2):192-8.
2008: Odelia Cooper; Jordan L Geller; Shlomo Melmed
Ovarian hyperstimulation syndrome caused by an FSH-secreting pituitary adenoma.
Nature clinical practice. Endocrinology & metabolism 2008;4(4):234-8.
2008: Gil Y Melmed; Shane M Devlin; George Vlotides; Deepti Dhall; Soraya Ross; Run Yu; Shlomo Melmed
Anti-aging therapy with human growth hormone associated with metastatic colon cancer in a patient with Crohn's colitis.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2008;6(3):360-3.
2008: Anat Ben-Shlomo; Shlomo Melmed
Acromegaly.
Endocrinology and metabolism clinics of North America 2008;37(1):101-22, viii.
2008: Shlomo Melmed
Update in pituitary disease.
The Journal of clinical endocrinology and metabolism 2008;93(2):331-8.
2007: Anat Ben-Shlomo; Shlomo Melmed
Pasireotide--a somatostatin analog for the potential treatment of acromegaly, neuroendocrine tumors and Cushing's disease.
IDrugs : the investigational drugs journal 2007;10(12):885-95.
2007: Anna Gruszka; Song-Guang Ren; Jesse Dong; Michael D Culler; Shlomo Melmed
Regulation of growth hormone and prolactin gene expression and secretion by chimeric somatostatin-dopamine molecules.
Endocrinology 2007;148(12):6107-14.
2007: Vera Chesnokova; Svetlana Zonis; Tami Rubinek; Run Yu; Anat Ben-Shlomo; Kalman Kovacs; Kolja Wawrowsky; Shlomo Melmed
Senescence mediates pituitary hypoplasia and restrains pituitary tumor growth.
Cancer research 2007;67(21):10564-72.
2007: Anat Ben-Shlomo; Oxana Pichurin; Nicole J Barshop; Kolja Wawrowsky; John Taylor; Michael D Culler; Vera Chesnokova; Ning-Ai Liu; Shlomo Melmed
Selective regulation of somatostatin receptor subtype signaling: evidence for constitutive receptor activation.
Molecular endocrinology (Baltimore, Md.) 2007;21(10):2565-78.
2007: Tami Rubinek; Vera Chesnokova; Ido Wolf; Kolja Wawrowsky; George Vlotides; Shlomo Melmed
Discordant proliferation and differentiation in pituitary tumor-transforming gene-null bone marrow stem cells.
American journal of physiology. Cell physiology 2007;293(3):C1082-92.
2007: Y Tong; Y Tan; C Zhou; Shlomo Melmed
Pituitary tumor transforming gene interacts with Sp1 to modulate G1/S cell phase transition.
Oncogene 2007;26(38):5596-605.
2007: Shlomo Melmed
Aryl hydrocarbon receptor interacting protein and pituitary tumorigenesis: another interesting protein.
The Journal of clinical endocrinology and metabolism 2007;92(5):1617-9.
2007: George Vlotides; Tamar Eigler; Shlomo Melmed
Pituitary tumor-transforming gene: physiology and implications for tumorigenesis.
Endocrine reviews 2007;28(2):165-86.
2006: Shlomo Melmed
Medical progress: Acromegaly.
The New England journal of medicine 2006;355(24):2558-73.
2006: Run Yu; Vivien Bonert; Inbar Saporta; Leslie J Raffel; Shlomo Melmed
Aryl hydrocarbon receptor interacting protein variants in sporadic pituitary adenomas.
The Journal of clinical endocrinology and metabolism 2006;91(12):5126-9.
2006: George Vlotides; M Cruz-Soto; Tami Rubinek; T Eigler; Christoph J Auernhammer; Shlomo Melmed
Mechanisms for growth factor-induced pituitary tumor transforming gene-1 expression in pituitary folliculostellate TtT/GF cells.
Molecular endocrinology (Baltimore, Md.) 2006;20(12):3321-35.
2006: Run Yu; Martha Cruz-Soto; Sergio Li Calzi; Hongxiang Hui; Shlomo Melmed
Murine pituitary tumor-transforming gene functions as a securin protein in insulin-secreting cells.
The Journal of endocrinology 2006;191(1):45-53.
2006: Ines Donangelo; Shiri Gutman; Eva Horvath; Kalman Kovacs; Kolja Wawrowsky; Michael Mount; Shlomo Melmed
Pituitary tumor transforming gene overexpression facilitates pituitary tumor development.
Endocrinology 2006;147(10):4781-91.
2006: Song-Guang Ren; Shlomo Melmed
Pyridoxal phosphate inhibits pituitary cell proliferation and hormone secretion.
Endocrinology 2006;147(8):3936-42.
2006: Vivien Bonert; Shlomo Melmed
Acromegaly with moderate hyperprolactinemia caused by an intrasellar macroadenoma.
Nature clinical practice. Endocrinology & metabolism 2006;2(7):408-12; quiz following 412.
2006: Anat Ben-Shlomo; Shlomo Melmed
Skin manifestations in acromegaly.
Clinics in dermatology 2006;24(4):256-9.
2006: M Fraenkel; J Caloyeras; Song-Guang Ren; Shlomo Melmed
Sex-steroid milieu determines diabetes rescue in pttg-null mice.
The Journal of endocrinology 2006;189(3):519-28.
2006: Pek Yee Lum; Yanqing Chen; Jun Zhu; john lamb; Shlomo Melmed; Susanna Wang; Tom A Drake; Aldons J Lusis; Eric E Schadt
Elucidating the murine brain transcriptional network in a segregating mouse population to identify core functional modules for obesity and diabetes.
Journal of neurochemistry 2006;97 Suppl 1():50-62.
2006: Ning-Ai Liu; Qian Liu; Kolja Wawrowsky; Zhongan Yang; Shuo Lin; Shlomo Melmed
Prolactin receptor signaling mediates the osmotic response of embryonic zebrafish lactotrophs.
Molecular endocrinology (Baltimore, Md.) 2006;20(4):871-80.
2006: Shlomo Melmed
Supplemental growth hormone in healthy adults: the endocrinologist's responsibility.
Nature clinical practice. Endocrinology & metabolism 2006;2(3):119.
2006: sadanori akita; Kozo Akino; Song-Guang Ren; Shlomo Melmed; Toshifumi Imaizumi; Akiyoshi Hirano
Elevated circulating leukemia inhibitory factor in patients with extensive burns.
Journal of burn care & research : official publication of the American Burn Association 2006;27(2):221-5.
2006: Thomas H Gillingwater; Thomas M Wishart; Philip E Chen; Jane E Haley; Kevin Robertson; Stephen H-F MacDonald; Susan Middleton; Kolja Wawrowski; Michael Shipston; Shlomo Melmed; David J A Wyllie; Paul A Skehel; Michael P Coleman; Richard R Ribchester
The neuroprotective WldS gene regulates expression of PTTG1 and erythroid differentiation regulator 1-like gene in mice and human cells.
Human molecular genetics 2006;15(4):625-35.
2006: Run Yu; Vivien Bonert; Martha Cruz-Soto; Shlomo Melmed
Cyclin-dependent kinase inhibitor gene polymorphisms in pituitary gigantism.
Endocrine 2006;29(1):119-20.
2006: Ines Donangelo; Shlomo Melmed
Implication of pituitary tropic status on tumor development.
Frontiers of hormone research 2006;35():1-8.
2006: Shlomo Melmed
2004 World Health Organization classification of pituitary tumors: what is new?
Acta neuropathologica 2006;111(1):78-9.
2005: Shlomo Melmed; FF Casanueva; F Cavagnini; Philippe Chanson; Lawrence A Frohman; R Gaillard; E Ghigo; Ken Ho; P Jaquet; David L Kleinberg; Steven W J Lamberts; E Laws; G Lombardi; M C Sheppard; M Thorner; Mary Lee Vance; J A H Wass; Andrea Giustina
Consensus statement: medical management of acromegaly.
European journal of endocrinology / European Federation of Endocrine Societies 2005;153(6):737-40.
2005: Kozo Akino; sadanori akita; Toru Mizuguchi; Ichiro Takumi; Run Yu; Xhi-yong Wang; Jacek Rozga; Achilles A Demetriou; Shlomo Melmed; Akira Ohtsuru; Shunichi Yamashita
A novel molecular marker of pituitary tumor transforming gene involves in a rat liver regeneration.
The Journal of surgical research 2005;129(1):142-6.
2005: Marcello D Bronstein; Shlomo Melmed
[Pituitary tumorigenesis].
Arquivos brasileiros de endocrinologia e metabologia 2005;49(5):615-25.
2005: Ines Donangelo; Shlomo Melmed
Treatment of acromegaly: future.
Endocrine 2005;28(1):123-8.
2005: Vera Chesnokova; Kalman Kovacs; Anna-Valeria Castro; Svetlana Zonis; Shlomo Melmed
Pituitary hypoplasia in Pttg-/- mice is protective for Rb+/- pituitary tumorigenesis.
Molecular endocrinology (Baltimore, Md.) 2005;19(9):2371-9.
2005: Shlomo Melmed; Richard Sternberg; David Cook; Anne Klibanski; Philippe Chanson; Vivien Bonert; Mary Lee Vance; David Rhew; David L Kleinberg; Ariel L Barkan
A critical analysis of pituitary tumor shrinkage during primary medical therapy in acromegaly.
The Journal of clinical endocrinology and metabolism 2005;90(7):4405-10.
2005: Anat Ben-Shlomo; Kolja Wawrowsky; Irina Proekt; Nathaniel M Wolkenfeld; Song-Guang Ren; John Taylor; Michael D Culler; Shlomo Melmed
Somatostatin receptor type 5 modulates somatostatin receptor type 2 regulation of adrenocorticotropin secretion.
The Journal of biological chemistry 2005;280(25):24011-21.
2005: Rula A Abbud; Ichiro Takumi; Erin M Barker; Song-Guang Ren; Dar-Yong Chen; Kolja Wawrowsky; Shlomo Melmed
Early multipotential pituitary focal hyperplasia in the alpha-subunit of glycoprotein hormone-driven pituitary tumor-transforming gene transgenic mice.
Molecular endocrinology (Baltimore, Md.) 2005;19(5):1383-91.
2005: I Donangelo; Shlomo Melmed
Pathophysiology of pituitary adenomas.
Journal of endocrinological investigation 2005;28(11 Suppl International):100-5.
2004: Robert D Murray; Kiwon Kim; Song-Guang Ren; Marjorie Chelly; Yutaka Umehara; Shlomo Melmed
Central and peripheral actions of somatostatin on the growth hormone-IGF-I axis.
The Journal of clinical investigation 2004;114(3):349-56.
2004: Vivien Bonert; Janet D Elashoff; Philip Barnett; Shlomo Melmed
Body mass index determines evoked growth hormone (GH) responsiveness in normal healthy male subjects: diagnostic caveat for adult GH deficiency.
The Journal of clinical endocrinology and metabolism 2004;89(7):3397-401.
2004: Robert D Murray; Kiwon Kim; Song-Guang Ren; Ian Lewis; Gisbert Weckbecker; Christian Bruns; Shlomo Melmed
The novel somatostatin ligand (SOM230) regulates human and rat anterior pituitary hormone secretion.
The Journal of clinical endocrinology and metabolism 2004;89(6):3027-32.
2004: Anthony P Heaney; Shlomo Melmed
Molecular targets in pituitary tumours.
Nature reviews. Cancer 2004;4(4):285-95.
2004: Rula A Abbud; Robert Kelleher; Shlomo Melmed
Cell-specific pituitary gene expression profiles after treatment with leukemia inhibitory factor reveal novel modulators for proopiomelanocortin expression.
Endocrinology 2004;145(2):867-80.
2004: Run Yu; Shlomo Melmed
Pituitary tumor transforming gene: an update.
Frontiers of hormone research 2004;32():175-85.
2003: Andrea Giustina; FF Casanueva; F Cavagnini; Philippe Chanson; David R Clemmons; Lawrence A Frohman; R Gaillard; Ken Ho; P Jaquet; David L Kleinberg; Steven W J Lamberts; G Lombardi; M Sheppard; C J Strasburger; Mary Lee Vance; J A H Wass; Shlomo Melmed
Diagnosis and treatment of acromegaly complications.
Journal of endocrinological investigation 2003;26(12):1242-7.
2003: Shlomo Melmed
Mechanisms for pituitary tumorigenesis: the plastic pituitary.
The Journal of clinical investigation 2003;112(11):1603-18.
2003: Song-Guang Ren; Sun Kim; John Taylor; Josse Dong; Jacques-Pierre Moreau; Michael D Culler; Shlomo Melmed
Suppression of rat and human growth hormone and prolactin secretion by a novel somatostatin/dopaminergic chimeric ligand.
The Journal of clinical endocrinology and metabolism 2003;88(11):5414-21.
2003: Run Yu; Wenge Lu; Jiandong Chen; Chris J McCabe; Shlomo Melmed
Overexpressed pituitary tumor-transforming gene causes aneuploidy in live human cells.
Endocrinology 2003;144(11):4991-8.
2003: Helen E Turner; Adrian L Harris; Shlomo Melmed; J A H Wass
Angiogenesis in endocrine tumors.
Endocrine reviews 2003;24(5):600-32.
2003: David R Clemmons; Kazuo Chihara; Pamela U Freda; Ken K Y Ho; Anne Klibanski; Shlomo Melmed; Stephen M Shalet; Christian J Strasburger; Peter J Trainer; Michael O Thorner
Optimizing control of acromegaly: integrating a growth hormone receptor antagonist into the treatment algorithm.
The Journal of clinical endocrinology and metabolism 2003;88(10):4759-67.
2003: Song-Guang Ren; John Taylor; Jesse Dong; Run Yu; Michael D Culler; Shlomo Melmed
Functional association of somatostatin receptor subtypes 2 and 5 in inhibiting human growth hormone secretion.
The Journal of clinical endocrinology and metabolism 2003;88(9):4239-45.
2003: Tami Rubinek; Run Yu; Moshe Hadani; Gad Barkai; Dvora Nass; Shlomo Melmed; Ilan Shimon
The cell adhesion molecules N-cadherin and neural cell adhesion molecule regulate human growth hormone: a novel mechanism for regulating pituitary hormone secretion.
The Journal of clinical endocrinology and metabolism 2003;88(8):3724-30.
2003: Anthony P Heaney; Manory Fernando; Shlomo Melmed
PPAR-gamma receptor ligands: novel therapy for pituitary adenomas.
The Journal of clinical investigation 2003;111(9):1381-8.
2003: Ning-Ai Liu; Haigen Huang; Zhongan Yang; Wiebke Herzog; Matthias Hammerschmidt; Shuo Lin; Shlomo Melmed
Pituitary corticotroph ontogeny and regulation in transgenic zebrafish.
Molecular endocrinology (Baltimore, Md.) 2003;17(5):959-66.
2003: Andrea Giustina; Shlomo Melmed
Acromegaly consensus: the next steps.
The Journal of clinical endocrinology and metabolism 2003;88(4):1913-4.
2003: Gregory A Horwitz; Irina Miklovsky; Anthony P Heaney; Song-Guang Ren; Shlomo Melmed
Human pituitary tumor-transforming gene (PTTG1) motif suppresses prolactin expression.
Molecular endocrinology (Baltimore, Md.) 2003;17(4):600-9.
2003: Zhiyong Wang; Enrico Moro; Kalman Kovacs; Run Yu; Shlomo Melmed
Pituitary tumor transforming gene-null male mice exhibit impaired pancreatic beta cell proliferation and diabetes.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(6):3428-32.
2003: Anat Ben-Shlomo; Shlomo Melmed
Clinical review 154: The role of pharmacotherapy in perioperative management of patients with acromegaly.
The Journal of clinical endocrinology and metabolism 2003;88(3):963-8.
2003: Anat Ben-Shlomo; Irina Miklovsky; Song-Guang Ren; William H Yong; Anthony P Heaney; Michael D Culler; Shlomo Melmed
Leukemia inhibitory factor regulates prolactin secretion in prolactinoma and lactotroph cells.
The Journal of clinical endocrinology and metabolism 2003;88(2):858-63.
2002: Rostyslav Stoika; Shlomo Melmed
Expression and function of pituitary tumour transforming gene for T-lymphocyte activation.
British journal of haematology 2002;119(4):1070-4.
2002: Anthony P Heaney; Manory Fernando; William H Yong; Shlomo Melmed
Functional PPAR-gamma receptor is a novel therapeutic target for ACTH-secreting pituitary adenomas.
Nature medicine 2002;8(11):1281-7.
2002: Shlomo Melmed; FF Casanueva; F Cavagnini; Philippe Chanson; Lawrence A Frohman; A Grossman; Ken Ho; David L Kleinberg; Steven W J Lamberts; E Laws; G Lombardi; Mary Lee Vance; K Von Werder; J A H Wass; Andrea Giustina
Guidelines for acromegaly management.
The Journal of clinical endocrinology and metabolism 2002;87(9):4054-8.
2002: R Yu; Song-Guang Ren; Shlomo Melmed
Proteasome inhibitors induce apoptosis in growth hormone- and prolactin-secreting rat pituitary tumor cells.
The Journal of endocrinology 2002;174(3):379-86.
2002: Vera Chesnokova; Shlomo Melmed
Minireview: Neuro-immuno-endocrine modulation of the hypothalamic-pituitary-adrenal (HPA) axis by gp130 signaling molecules.
Endocrinology 2002;143(5):1571-4.
2002: Vera Chesnokova; Anastasia Kariagina; Shlomo Melmed
Opposing effects of pituitary leukemia inhibitory factor and SOCS-3 on the ACTH axis response to inflammation.
American journal of physiology. Endocrinology and metabolism 2002;282(5):E1110-8.
2002: Shlomo Melmed; Mary Lee Vance; Ariel L Barkan; Bengt-Ake Bengtsson; David L Kleinberg; Anne Klibanski; Peter J Trainer
Current status and future opportunities for controlling acromegaly.
Pituitary 2002;5(3):185-96.
2002: Anthony P Heaney; Manory Fernando; Shlomo Melmed
Functional role of estrogen in pituitary tumor pathogenesis.
The Journal of clinical investigation 2002;109(2):277-83.
2001: Shlomo Melmed
Series introduction. The immuno-neuroendocrine interface.
The Journal of clinical investigation 2001;108(11):1563-6.
2001: Aart Jan Van der Lely; R K Hutson; Peter J Trainer; G M Besser; Ariel L Barkan; Laurence Katznelson; Anne Klibanski; VS Herman-Bonert; Shlomo Melmed; Mary Lee Vance; Pamela U Freda; P M Stewart; Keith E Friend; David R Clemmons; G Johannsson; Stavros Stavrou; David M Cook; Lawrence S Phillips; Christian J Strasburger; S Hackett; KA Zib; R J Davis; JA Scarlett; M O Thorner
Long-term treatment of acromegaly with pegvisomant, a growth hormone receptor antagonist.
Lancet 2001;358(9295):1754-9.
2001: Corinne Bousquet; Vera Chesnokova; Anastasia Kariagina; Audrey Ferrand; Shlomo Melmed
cAMP neuropeptide agonists induce pituitary suppressor of cytokine signaling-3: novel negative feedback mechanism for corticotroph cytokine action.
Molecular endocrinology (Baltimore, Md.) 2001;15(11):1880-90.
2001: Z Wang; Run Yu; Shlomo Melmed
Mice lacking pituitary tumor transforming gene show testicular and splenic hypoplasia, thymic hyperplasia, thrombocytopenia, aberrant cell cycle progression, and premature centromere division.
Molecular endocrinology (Baltimore, Md.) 2001;15(11):1870-9.
2001: Anat Ben-Shlomo; Shlomo Melmed
Acromegaly.
Endocrinology and metabolism clinics of North America 2001;30(3):565-83, vi.
2001: Shlomo Melmed
Acromegaly and cancer: not a problem?
The Journal of clinical endocrinology and metabolism 2001;86(7):2929-34.
2001: Run Yu; Shlomo Melmed
Oncogene activation in pituitary tumors.
Brain pathology (Zurich, Switzerland) 2001;11(3):328-41.
2001: Tami Rubinek; Moshe Hadani; Gad Barkai; Shlomo Melmed; Ilan Shimon
Prolactin (PRL)-releasing peptide stimulates PRL secretion from human fetal pituitary cultures and growth hormone release from cultured pituitary adenomas.
The Journal of clinical endocrinology and metabolism 2001;86(6):2826-30.
2001: H Ishikawa; Anthony P Heaney; Run Yu; Gregory A Horwitz; Shlomo Melmed
Human pituitary tumor-transforming gene induces angiogenesis.
The Journal of clinical endocrinology and metabolism 2001;86(2):867-74.
2000: Corinne Bousquet; M C Zatelli; Shlomo Melmed
Direct regulation of pituitary proopiomelanocortin by STAT3 provides a novel mechanism for immuno-neuroendocrine interfacing.
The Journal of clinical investigation 2000;106(11):1417-25.
2000: R Yu; Anthony P Heaney; W Lu; Jiandong Chen; Shlomo Melmed
Pituitary tumor transforming gene causes aneuploidy and p53-dependent and p53-independent apoptosis.
The Journal of biological chemistry 2000;275(47):36502-5.
2000: Vera Chesnokova; Shlomo Melmed
Leukemia inhibitory factor mediates the hypothalamic pituitary adrenal axis response to inflammation.
Endocrinology 2000;141(11):4032-40.
2000: H G Maheshwari; TR Prezant; V Herman-Bonert; H Shahinian; Kalman Kovacs; Shlomo Melmed
Long-acting peptidomimergic control of gigantism caused by pituitary acidophilic stem cell adenoma.
The Journal of clinical endocrinology and metabolism 2000;85(9):3409-16.
2000: VS Herman-Bonert; KA Zib; J A Scarlett; Shlomo Melmed
Growth hormone receptor antagonist therapy in acromegalic patients resistant to somatostatin analogs.
The Journal of clinical endocrinology and metabolism 2000;85(8):2958-61.
2000: Run Yu; Song-Guang Ren; Gregory A Horwitz; Z Wang; Shlomo Melmed
Pituitary tumor transforming gene (PTTG) regulates placental JEG-3 cell division and survival: evidence from live cell imaging.
Molecular endocrinology (Baltimore, Md.) 2000;14(8):1137-46.
2000: Z Wang; Shlomo Melmed
Pituitary tumor transforming gene (PTTG) transforming and transactivation activity.
The Journal of biological chemistry 2000;275(11):7459-61.
2000: Anthony P Heaney; Shlomo Melmed
New pituitary oncogenes.
Endocrine-related cancer 2000;7(1):3-15.
2000: Anthony P Heaney; R Singson; C J McCabe; V Nelson; M Nakashima; Shlomo Melmed
Expression of pituitary-tumour transforming gene in colorectal tumours.
Lancet 2000;355(9205):716-9.
2000: Andrea Giustina; Ariel L Barkan; FF Casanueva; F Cavagnini; Lawrence A Frohman; Ken Ho; J Veldhuis; J A H Wass; K Von Werder; Shlomo Melmed
Criteria for cure of acromegaly: a consensus statement.
The Journal of clinical endocrinology and metabolism 2000;85(2):526-9.
2000: Z Wang; Shlomo Melmed
Characterization of the murine pituitary tumor transforming gene (PTTG) and its promoter.
Endocrinology 2000;141(2):763-71.
2000: CJ Auernhammer; Corinne Bousquet; Vera Chesnokova; Shlomo Melmed
SOCS proteins: modulators of neuroimmunoendocrine functions. Impact on corticotroph LIF signaling.
Annals of the New York Academy of Sciences 2000;917():658-64.
2000: M R Drange; N R Fram; V Herman-Bonert; Shlomo Melmed
Pituitary tumor registry: a novel clinical resource.
The Journal of clinical endocrinology and metabolism 2000;85(1):168-74.
1999: Anthony P Heaney; Gregory A Horwitz; Z Wang; R Singson; Shlomo Melmed
Early involvement of estrogen-induced pituitary tumor transforming gene and fibroblast growth factor expression in prolactinoma pathogenesis.
Nature medicine 1999;5(11):1317-21.
1999: Corinne Bousquet; Christiane Susini; Shlomo Melmed
Inhibitory roles for SHP-1 and SOCS-3 following pituitary proopiomelanocortin induction by leukemia inhibitory factor.
The Journal of clinical investigation 1999;104(9):1277-85.
1999: Anthony P Heaney; Shlomo Melmed
Pituitary tumour transforming gene: a novel factor in pituitary tumour formation.
Baillière's best practice & research. Clinical endocrinology & metabolism 1999;13(3):367-80.
1999: Song-Guang Ren; J Seliktar; X Li; Jerome M Hershman; Glenn D Braunstein; Shlomo Melmed
In vivo and in vitro regulation of thyroid leukemia inhibitory factor (LIF): marker of hypothyroidism.
The Journal of clinical endocrinology and metabolism 1999;84(8):2883-7.
1999: CJ Auernhammer; Corinne Bousquet; Shlomo Melmed
Autoregulation of pituitary corticotroph SOCS-3 expression: characterization of the murine SOCS-3 promoter.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(12):6964-9.
1999: M R Drange; Shlomo Melmed
Molecular pathogenesis of acromegaly.
Pituitary 1999;2(1):43-50.
1999: Corinne Bousquet; Shlomo Melmed
Critical role for STAT3 in murine pituitary adrenocorticotropin hormone leukemia inhibitory factor signaling.
The Journal of biological chemistry 1999;274(16):10723-30.
1999: CJ Auernhammer; Shlomo Melmed
Interleukin-11 stimulates proopiomelanocortin gene expression and adrenocorticotropin secretion in corticotroph cells: evidence for a redundant cytokine network in the hypothalamo-pituitary-adrenal axis.
Endocrinology 1999;140(4):1559-66.
1999: Shlomo Melmed
Pathogenesis of pituitary tumors.
Endocrinology and metabolism clinics of North America 1999;28(1):1-12, v.
1999: TR Prezant; P Kadioglu; Shlomo Melmed
An intronless homolog of human proto-oncogene hPTTG is expressed in pituitary tumors: evidence for hPTTG family.
The Journal of clinical endocrinology and metabolism 1999;84(3):1149-52.
1999: X Zhang; Gregory A Horwitz; Anthony P Heaney; M Nakashima; TR Prezant; M D Bronstein; Shlomo Melmed
Pituitary tumor transforming gene (PTTG) expression in pituitary adenomas.
The Journal of clinical endocrinology and metabolism 1999;84(2):761-7.
1999: X Zhang; Gregory A Horwitz; TR Prezant; A Valentini; M Nakashima; M D Bronstein; Shlomo Melmed
Structure, expression, and function of human pituitary tumor-transforming gene (PTTG).
Molecular endocrinology (Baltimore, Md.) 1999;13(1):156-66.
1998: H Yano; Carol Readhead; M Nakashima; Song-Guang Ren; Shlomo Melmed
Pituitary-directed leukemia inhibitory factor transgene causes Cushing's syndrome: neuro-immune-endocrine modulation of pituitary development.
Molecular endocrinology (Baltimore, Md.) 1998;12(11):1708-20.
1998: Ilan Shimon; X Yan; D A Magoffin; Theodore C Friedman; Shlomo Melmed
Intact leptin receptor is selectively expressed in human fetal pituitary and pituitary adenomas and signals human fetal pituitary growth hormone secretion.
The Journal of clinical endocrinology and metabolism 1998;83(11):4059-64.
1998: Z Wang; Shlomo Melmed
Functional map of a placenta-specific enhancer of the human leukemia inhibitory factor receptor gene.
The Journal of biological chemistry 1998;273(40):26069-77.
1998: Ilan Shimon; Shlomo Melmed
Management of pituitary tumors.
Annals of internal medicine 1998;129(6):472-83.
1998: M R Drange; Shlomo Melmed
Long-acting lanreotide induces clinical and biochemical remission of acromegaly caused by disseminated growth hormone-releasing hormone-secreting carcinoid.
The Journal of clinical endocrinology and metabolism 1998;83(9):3104-9.
1998: CB Newman; Shlomo Melmed; A George; D Torigian; M Duhaney; P Snyder; W Young; A Klibanski; Mark E Molitch; R Gagel; L Sheeler; D Cook; W Malarkey; I Jackson; Mary Lee Vance; Ariel L Barkan; Lawrence A Frohman; David L Kleinberg
Octreotide as primary therapy for acromegaly.
The Journal of clinical endocrinology and metabolism 1998;83(9):3034-40.
1998: Shlomo Melmed; I Jackson; David L Kleinberg; A Klibanski
Current treatment guidelines for acromegaly.
The Journal of clinical endocrinology and metabolism 1998;83(8):2646-52.
1998: CJ Auernhammer; Vera Chesnokova; Corinne Bousquet; Shlomo Melmed
Pituitary corticotroph SOCS-3: novel intracellular regulation of leukemia-inhibitory factor-mediated proopiomelanocortin gene expression and adrenocorticotropin secretion.
Molecular endocrinology (Baltimore, Md.) 1998;12(7):954-61.
1998: Shlomo Melmed
gp130-Related Cytokines and Their Receptors in the Pituitary.
Trends in endocrinology and metabolism: TEM 1998;9(4):155-61.
1998: Seisho Takeuchi; H Phillip Koeffler; D R Hinton; I Miyoshi; Shlomo Melmed; Ilan Shimon
Mutation and expression analysis of the cyclin-dependent kinase inhibitor gene p27/Kip1 in pituitary tumors.
The Journal of endocrinology 1998;157(2):337-41.
1998: DW Ray; Song-Guang Ren; Shlomo Melmed
Leukemia inhibitory factor regulates proopiomelanocortin transcription.
Annals of the New York Academy of Sciences 1998;840():162-73.
1998: Vera Chesnokova; CJ Auernhammer; Shlomo Melmed
Murine leukemia inhibitory factor gene disruption attenuates the hypothalamo-pituitary-adrenal axis stress response.
Endocrinology 1998;139(5):2209-16.
1998: CJ Auernhammer; Vera Chesnokova; Shlomo Melmed
Leukemia inhibitory factor modulates interleukin-1beta-induced activation of the hypothalamo-pituitary-adrenal axis.
Endocrinology 1998;139(5):2201-8.
1998: TR Prezant; J Levine; Shlomo Melmed
Molecular characterization of the men1 tumor suppressor gene in sporadic pituitary tumors.
The Journal of clinical endocrinology and metabolism 1998;83(4):1388-91.
1998: Song-Guang Ren; J Seliktar; X Li; Glenn D Braunstein; Shlomo Melmed
Measurement of leukemia inhibitory factor in biological fluids by radioimmunoassay.
The Journal of clinical endocrinology and metabolism 1998;83(4):1275-83.
1998: VS Herman-Bonert; M Seliverstov; Shlomo Melmed
Pregnancy in acromegaly: successful therapeutic outcome.
The Journal of clinical endocrinology and metabolism 1998;83(3):727-31.
1998: Ilan Shimon; David R Hinton; M H Weiss; Shlomo Melmed
Prolactinomas express human heparin-binding secretory transforming gene (hst) protein product: marker of tumour invasiveness.
Clinical endocrinology 1998;48(1):23-9.
1998: Ilan Shimon; X Yan; Shlomo Melmed
Human fetal pituitary expresses functional growth hormone-releasing peptide receptors.
The Journal of clinical endocrinology and metabolism 1998;83(1):174-8.
1997: Shlomo Melmed
gp130-Related cytokines and their receptors in the pituitary.
Trends in endocrinology and metabolism: TEM 1997;8(10):391-7.
1997: Qiao-Ling Li; H Yano; Song-Guang Ren; X Li; Theodore C Friedman; Shlomo Melmed
Leukemia inhibitory factor (LIF) modulates pro-opiomelanocortin (POMC) gene regulation in stably transfected AtT-20 cells overexpressing LIF.
Endocrine 1997;7(3):325-30.
1997: Ilan Shimon; X Yan; John E Taylor; M H Weiss; Michael D Culler; Shlomo Melmed
Somatostatin receptor (SSTR) subtype-selective analogues differentially suppress in vitro growth hormone and prolactin in human pituitary adenomas. Novel potential therapy for functional pituitary tumors.
The Journal of clinical investigation 1997;100(9):2386-92.
1997: Z Wang; Shlomo Melmed
Identification of an upstream enhancer within a functional promoter of the human leukemia inhibitory factor receptor gene and its alternative promoter usage.
The Journal of biological chemistry 1997;272(44):27957-65.
1997: Ilan Shimon; Shlomo Melmed
Structure and function of somatostatin receptors in growth hormone control.
The Journal of endocrinology 1997;155 Suppl 1():S3-6; discussion S7-8.
1997: Ilan Shimon; X Yan; DW Ray; Shlomo Melmed
Cytokine-dependent gp130 receptor subunit regulates human fetal pituitary adrenocorticotropin hormone and growth hormone secretion.
The Journal of clinical investigation 1997;100(2):357-63.
1997: Song-Guang Ren; Shlomo Melmed; Glenn D Braunstein
Decidual leukemia inhibitory factor production and action on human chorionic gonadotropin secretion at different stages of gestation in vitro.
Early pregnancy : biology and medicine : the official journal of the Society for the Investigation of Early Pregnancy 1997;3(2):102-8.
1997: I Shimon; Shlomo Melmed
Genetic basis of endocrine disease: pituitary tumor pathogenesis.
The Journal of clinical endocrinology and metabolism 1997;82(6):1675-81.
1997: sadanori akita; Carol Readhead; L Stefaneanu; J Fine; A Tampanaru-Sarmesiu; Kalman Kovacs; Shlomo Melmed
Pituitary-directed leukemia inhibitory factor transgene forms Rathke's cleft cysts and impairs adult pituitary function. A model for human pituitary Rathke's cysts.
The Journal of clinical investigation 1997;99(10):2462-9.
1997: Corinne Bousquet; DW Ray; Shlomo Melmed
A common pro-opiomelanocortin-binding element mediates leukemia inhibitory factor and corticotropin-releasing hormone transcriptional synergy.
The Journal of biological chemistry 1997;272(16):10551-7.
1997: D Ray; Shlomo Melmed
Pituitary cytokine and growth factor expression and action.
Endocrine reviews 1997;18(2):206-28.
1997: Liming Pei; Shlomo Melmed
Isolation and characterization of a pituitary tumor-transforming gene (PTTG).
Molecular endocrinology (Baltimore, Md.) 1997;11(4):433-41.
1997: Ilan Shimon; John E Taylor; Jesse Z Dong; R A Bitonte; S Kim; B Morgan; David H Coy; Michael D Culler; Shlomo Melmed
Somatostatin receptor subtype specificity in human fetal pituitary cultures. Differential role of SSTR2 and SSTR5 for growth hormone, thyroid-stimulating hormone, and prolactin regulation.
The Journal of clinical investigation 1997;99(4):789-98.
1997: I Shimon; Shlomo Melmed
Growth hormone- and growth-hormone-releasing hormone-producing tumors.
Cancer treatment and research 1997;89():1-24.
1996: sadanori akita; P Michael Conn; Shlomo Melmed
Leukemia inhibitory factor (LIF) induces acute adrenocorticotrophic hormone (ACTH) secretion in fetal rhesus macaque primates: a novel dynamic test of pituitary function.
The Journal of clinical endocrinology and metabolism 1996;81(11):4170-8.
1996: Mordechai Shohat; D Tick; S Barakat; X Bu; Shlomo Melmed; David L Rimoin
Short-term recombinant human growth hormone treatment increases growth rate in achondroplasia.
The Journal of clinical endocrinology and metabolism 1996;81(11):4033-7.
1996: B Stefana; D W Ray; Shlomo Melmed
Leukemia inhibitory factor induces differentiation of pituitary corticotroph function: an immuno-neuroendocrine phenotypic switch.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(22):12502-6.
1996: Shlomo Melmed
Molecular pathophysiology of acromegaly.
Acta paediatrica (Oslo, Norway : 1992). Supplement 1996;417():45-8.
1996: Shlomo Melmed
Acromegaly.
Metabolism: clinical and experimental 1996;45(8 Suppl 1):51-2.
1996: sadanori akita; J Malkin; Shlomo Melmed
Disrupted murine leukemia inhibitory factor (LIF) gene attenuates adrenocorticotropic hormone (ACTH) secretion.
Endocrinology 1996;137(7):3140-3.
1996: Z Wang; S G Ren; Shlomo Melmed
Hypothalamic and pituitary leukemia inhibitory factor gene expression in vivo: a novel endotoxin-inducible neuro-endocrine interface.
Endocrinology 1996;137(7):2947-53.
1996: Shlomo Melmed
Unwanted effects of growth hormone excess in the adult.
Journal of pediatric endocrinology & metabolism : JPEM 1996;9 Suppl 3():369-74.
1996: D W Ray; Song-Guang Ren; Shlomo Melmed
Leukemia inhibitory factor (LIF) stimulates proopiomelanocortin (POMC) expression in a corticotroph cell line. Role of STAT pathway.
The Journal of clinical investigation 1996;97(8):1852-9.
1996: Shlomo Melmed; S Yamashita; H Yamasaki; James A Fagin; H Namba; H Yamamoto; M Weber; S Morita; J Webster; D Prager
IGF-I receptor signalling: lessons from the somatotroph.
Recent progress in hormone research 1996;51():189-215; discussion 215-6.
1996: Ilan Shimon; A Hüttner; Jonathan Said; O M Spirina; Shlomo Melmed
Heparin-binding secretory transforming gene (hst) facilitates rat lactotrope cell tumorigenesis and induces prolactin gene transcription.
The Journal of clinical investigation 1996;97(1):187-95.
1995: C B Newman; Shlomo Melmed; P J Snyder; W F Young; L D Boyajy; Robert B Levy; W N Stewart; A Klibanski; M E Molitch; R F Gagel
Safety and efficacy of long-term octreotide therapy of acromegaly: results of a multicenter trial in 103 patients--a clinical research center study.
The Journal of clinical endocrinology and metabolism 1995;80(9):2768-75.
1995: H Takino; V Herman; M Weiss; Shlomo Melmed
Purine-binding factor (nm23) gene expression in pituitary tumors: marker of adenoma invasiveness.
The Journal of clinical endocrinology and metabolism 1995;80(5):1733-8.
1995: L Pei; Shlomo Melmed; B Scheithauer; K Kovacs; W F Benedict; D Prager
Frequent loss of heterozygosity at the retinoblastoma susceptibility gene (RB) locus in aggressive pituitary tumors: evidence for a chromosome 13 tumor suppressor gene other than RB.
Cancer research 1995;55(8):1613-6.
1995: sadanori akita; J Webster; S G Ren; H Takino; Jonathan Said; O Zand; Shlomo Melmed
Human and murine pituitary expression of leukemia inhibitory factor. Novel intrapituitary regulation of adrenocorticotropin hormone synthesis and secretion.
The Journal of clinical investigation 1995;95(3):1288-98.
1995: Y Greenman; D Prager; Shlomo Melmed
The IGF-I receptor sub-membrane domain is intact in GH-secreting pituitary tumours.
Clinical endocrinology 1995;42(2):169-72.
1994: Y Greenman; Shlomo Melmed
Expression of three somatostatin receptor subtypes in pituitary adenomas: evidence for preferential SSTR5 expression in the mammosomatotroph lineage.
The Journal of clinical endocrinology and metabolism 1994;79(3):724-9.
1994: D Prager; H Yamasaki; M M Weber; Shlomo Melmed
Role of the insulin-like growth factors in regulating neuroendocrine function.
Neurobiology of aging 1994;15(4):569-72.
1994: J Webster; D Prager; Shlomo Melmed
Insulin-like growth factor-1 activation of extracellular signal-related kinase-1 and -2 in growth hormone-secreting cells.
Molecular endocrinology (Baltimore, Md.) 1994;8(5):539-44.
1994: D Prager; H L Li; H Yamasaki; Shlomo Melmed
Human insulin-like growth factor I receptor internalization. Role of the juxtamembrane domain.
The Journal of biological chemistry 1994;269(16):11934-7.
1994: L Pei; Shlomo Melmed; B Scheithauer; K Kovacs; D Prager
H-ras mutations in human pituitary carcinoma metastases.
The Journal of clinical endocrinology and metabolism 1994;78(4):842-6.
1994: D Prager; H L Li; S Asa; Shlomo Melmed
Dominant negative inhibition of tumorigenesis in vivo by human insulin-like growth factor I receptor mutant.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(6):2181-5.
1994: Shlomo Melmed
Pituitary neoplasia.
Endocrinology and metabolism clinics of North America 1994;23(1):81-92.
1994: Y Greenman; Shlomo Melmed
Heterogeneous expression of two somatostatin receptor subtypes in pituitary tumors.
The Journal of clinical endocrinology and metabolism 1994;78(2):398-403.
1993: H Yamamoto; D Prager; H Yamasaki; Shlomo Melmed
Rat pituitary GC cell insulin-like growth factor-I receptor regulation.
Endocrinology 1993;133(3):1420-5.
1993: D Prager; Shlomo Melmed
Somatotroph insulin-like growth factor-I signaling.
Annals of the New York Academy of Sciences 1993;692():102-12.
1993: Shlomo Melmed
Medical management of acromegaly--what and when?
Acta endocrinologica 1993;129 Suppl 1():13-7.
1993: V Herman; N Z Drazin; Rivkah Gonsky; Shlomo Melmed
Molecular screening of pituitary adenomas for gene mutations and rearrangements.
The Journal of clinical endocrinology and metabolism 1993;77(1):50-5.
1993: S Ezzat; Shlomo Melmed; D Endres; D R Eyre; F R Singer
Biochemical assessment of bone formation and resorption in acromegaly.
The Journal of clinical endocrinology and metabolism 1993;76(6):1452-7.
1993: H Yamasaki; D Prager; Shlomo Melmed
Structure-function of the human insulin-like growth factor-I receptor: a discordance of somatotroph internalization and signaling.
Molecular endocrinology (Baltimore, Md.) 1993;7(5):681-5.
1993: D Prager; M M Weber; S Gebremedhin; Shlomo Melmed
Interaction between insulin and thyroid hormone in rat pituitary tumour cells: insulin attenuates tri-iodothyronine-induced growth hormone mRNA levels.
The Journal of endocrinology 1993;137(1):107-14.
1993: S Ezzat; C Ezrin; S Yamashita; Shlomo Melmed
Recurrent acromegaly resulting from ectopic growth hormone gene expression by a metastatic pancreatic tumor.
Cancer 1993;71(1):66-70.
1992: S Ezzat; S G Ren; Glenn D Braunstein; Shlomo Melmed
Octreotide stimulates insulin-like growth factor-binding protein-1: a potential pituitary-independent mechanism for drug action.
The Journal of clinical endocrinology and metabolism 1992;75(6):1459-63.
1992: D Prager; H Yamasaki; M M Weber; S Gebremedhin; Shlomo Melmed
Human insulin-like growth factor I receptor function in pituitary cells is suppressed by a dominant negative mutant.
The Journal of clinical investigation 1992;90(5):2117-22.
1992: M M Weber; Shlomo Melmed; J Rosenbloom; H Yamasaki; D Prager
Rat somatotroph insulin-like growth factor-II (IGF-II) signaling: role of the IGF-I receptor.
Endocrinology 1992;131(5):2147-53.
1992: S G Ren; S Ezzat; Shlomo Melmed; Glenn D Braunstein
Somatostatin analog induces insulin-like growth factor binding protein-1 (IGFBP-1) expression in human hepatoma cells.
Endocrinology 1992;131(5):2479-81.
1992: H Yamasaki; D Prager; S Gebremedhin; Shlomo Melmed
Human insulin-like growth factor I receptor 950tyrosine is required for somatotroph growth factor signal transduction.
The Journal of biological chemistry 1992;267(29):20953-8.
1992: Shlomo Melmed
Etiology of pituitary acromegaly.
Endocrinology and metabolism clinics of North America 1992;21(3):539-51.
1992: S Ezzat; Shlomo Melmed
Endocrine applications of the somatostatin analogue octreotide (Sandostatin).
Metabolism: clinical and experimental 1992;41(9 Suppl 2):34-8.
1991: Rivkah Gonsky; V Herman; Shlomo Melmed; James A Fagin
Transforming DNA sequences present in human prolactin-secreting pituitary tumors.
Molecular endocrinology (Baltimore, Md.) 1991;5(11):1687-95.
1991: Shlomo Melmed
Extrapituitary acromegaly.
Endocrinology and metabolism clinics of North America 1991;20(3):507-18.
1991: S Ezzat; S G Ren; Glenn D Braunstein; Shlomo Melmed
Octreotide stimulates insulin-like growth factor binding protein-1 (IGFBP-1) levels in acromegaly.
The Journal of clinical endocrinology and metabolism 1991;73(2):441-3.
1991: S Ezzat; Shlomo Melmed
Acromegaly: etiology, diagnosis and management.
Comprehensive therapy 1991;17(7):31-5.
1991: H Yamasaki; D Prager; S Gebremedhin; Shlomo Melmed
Insulin-like growth factor-I (IGF-I) attenuation of growth hormone is enhanced by overexpression of pituitary IGF-I receptors.
Molecular endocrinology (Baltimore, Md.) 1991;5(7):890-6.
1991: S Ezzat; Shlomo Melmed
Clinical review 18: Are patients with acromegaly at increased risk for neoplasia?
The Journal of clinical endocrinology and metabolism 1991;72(2):245-9.
1991: S Ezzat; D Laks; J Oster; Shlomo Melmed
Growth hormone regulation in primary fetal and neonatal rat pituitary cell cultures: the role of thyroid hormone.
Endocrinology 1991;128(2):937-43.
1991: H Yamasaki; D Prager; S Gebremedhin; L Moise; Shlomo Melmed
Binding and action of insulin-like growth factor I in pituitary tumor cells.
Endocrinology 1991;128(2):857-62.
1990: V Herman; James A Fagin; Rivkah Gonsky; K Kovacs; Shlomo Melmed
Clonal origin of pituitary adenomas.
The Journal of clinical endocrinology and metabolism 1990;71(6):1427-33.
1990: D Prager; S Gebremedhin; Shlomo Melmed
An insulin-induced DNA-binding protein for the human growth hormone gene.
The Journal of clinical investigation 1990;85(5):1680-5.
1990: Shlomo Melmed
Acromegaly.
The New England journal of medicine 1990;322(14):966-77.
1989: James A Fagin; C Fernandez-Mejia; Shlomo Melmed
Pituitary insulin-like growth factor-I gene expression: regulation by triiodothyronine and growth hormone.
Endocrinology 1989;125(5):2385-91.
1989: S Barakat; Shlomo Melmed
Reversible shrinkage of a growth hormone-secreting pituitary adenoma by a long-acting somatostatin analogue, octreotide.
Archives of internal medicine 1989;149(6):1443-5.
1989: S Morita; C Fernandez-Mejia; Shlomo Melmed
Retinoic acid selectively stimulates growth hormone secretion and messenger ribonucleic acid levels in rat pituitary cells.
Endocrinology 1989;124(5):2052-6.
1989: H Namba; S Morita; Shlomo Melmed
Insulin-like growth factor-I action on growth hormone secretion and messenger ribonucleic acid levels: interaction with somatostatin.
Endocrinology 1989;124(4):1794-9.
1988: D Prager; Shlomo Melmed
Insulin regulates expression of the human growth hormone gene in transfected cells.
The Journal of biological chemistry 1988;263(32):16580-5.
1988: Shlomo Melmed; F H Ziel; Glenn D Braunstein; T Downs; Lawrence A Frohman
Medical management of acromegaly due to ectopic production of growth hormone-releasing hormone by a carcinoid tumor.
The Journal of clinical endocrinology and metabolism 1988;67(2):395-9.
1988: D Prager; S Yamashita; Shlomo Melmed
Insulin regulates prolactin secretion and messenger ribonucleic acid levels in pituitary cells.
Endocrinology 1988;122(6):2946-52.
1987: S Morita; S Yamashita; Shlomo Melmed
Insulin-like growth factor I action on rat anterior pituitary cells: effects of intracellular messengers on growth hormone secretion and messenger ribonucleic acid levels.
Endocrinology 1987;121(6):2000-6.
1987: S Yamashita; J Ong; Shlomo Melmed
Regulation of human growth hormone gene expression by insulin-like growth factor I in transfected cells.
The Journal of biological chemistry 1987;262(27):13254-7.
1987: Shlomo Melmed; R J Rushakoff
Ectopic pituitary and hypothalamic hormone syndromes.
Endocrinology and metabolism clinics of North America 1987;16(3):805-21.