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Shlomo Melmed

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Disorders

Anatomy

Pituitary Gland

Chemicals & Drugs

Living Beings

Mice
Rats

Physiology

Transfection

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Co-Publications
Name
24
Ren, Song-Guang
13
Yu, Run
13
Chesnokova, Vera
13
Heaney, Anthony
12
Ben-Shlomo, Anat
12
Wawrowsky, Kolja
12
Shimon, Ilan
10
Culler, Michael
8
Bousquet, Corinne
7
Braunstein, Glenn
7
Barkan, Ariel
7
Bonert, Vivien
7
Kleinberg, David
7
Kovacs, Kalman
7
Vance, Mary Lee

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Publications

TOP 3
Melmed Shlomo
Acromegaly pathogenesis and treatment.
Ben-Shlomo Anat; Schmid Herbert; Wawrowsky Kolja; Pichurin Oxana; Hubina Erika; Chesnokova Vera; Liu Ning-Ai; Culler Michael; Melmed Shlomo
Differential ligand-mediated pituitary somatostatin receptor subtype signaling: implications for corticotroph tumor therapy.
Vlotides George; Chen Yen-Hao; Eigler Tamar; Ren Song-Guang; Melmed Shlomo
Fibroblast growth factor-2 autofeedback regulation in pituitary folliculostellate TtT/GF cells.

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All Publications

2009: Melmed Shlomo
Acromegaly pathogenesis and treatment.
The Journal of clinical investigation 2009;119(11):3189-202.
2009: Ben-Shlomo Anat; Schmid Herbert; Wawrowsky Kolja; Pichurin Oxana; Hubina Erika; Chesnokova Vera; Liu Ning-Ai; Culler Michael; Melmed Shlomo
Differential ligand-mediated pituitary somatostatin receptor subtype signaling: implications for corticotroph tumor therapy.
The Journal of clinical endocrinology and metabolism 2009;94(11):4342-50.
2009: Vlotides George; Chen Yen-Hao; Eigler Tamar; Ren Song-Guang; Melmed Shlomo
Fibroblast growth factor-2 autofeedback regulation in pituitary folliculostellate TtT/GF cells.
Endocrinology 2009;150(7):3252-8.
2009: Vlotides George; Cooper Odelia; Chen Yen-Hao; Ren Song-Guang; Greenman Yona; Melmed Shlomo
Heregulin regulates prolactinoma gene expression.
Cancer research 2009;69(10):4209-16.
2009: Melmed S; Colao A; Barkan A; Molitch M; Grossman A B; Kleinberg D; Clemmons D; Chanson P; Laws E; Schlechte J; Vance M L; Ho K; Giustina A;
Guidelines for acromegaly management: an update.
The Journal of clinical endocrinology and metabolism 2009;94(5):1509-17.
2009: Chesnokova Vera; Melmed Shlomo
Pituitary tumour-transforming gene (PTTG) and pituitary senescence.
Hormone research 2009;71 Suppl 2():82-7.
2009: Ben-Shlomo Anat; Zhou Cuiqi; Pichurin Oxana; Chesnokova Vera; Liu Ning-Ai; Culler Michael D; Melmed Shlomo
Constitutive somatostatin receptor activity determines tonic pituitary cell response.
Molecular endocrinology (Baltimore, Md.) 2009;23(3):337-48.
2009: Carmichael John D; Bonert Vivien S; Mirocha James M; Melmed Shlomo
The utility of oral glucose tolerance testing for diagnosis and assessment of treatment outcomes in 166 patients with acromegaly.
The Journal of clinical endocrinology and metabolism 2009;94(2):523-7.
2008: Chesnokova Vera; Zonis Svetlana; Kovacs Kalman; Ben-Shlomo Anat; Wawrowsky Kolja; Bannykh Serguei; Melmed Shlomo
p21(Cip1) restrains pituitary tumor growth.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(45):17498-503.
2008: Tong Y; Ben-Shlomo A; Zhou C; Wawrowsky K; Melmed S
Pituitary tumor transforming gene 1 regulates Aurora kinase A activity.
Oncogene 2008;27(49):6385-95.
2008: Bonert Vivien S; Kennedy Laurence; Petersenn Stephan; Barkan Ariel; Carmichael John; Melmed Shlomo
Lipodystrophy in patients with acromegaly receiving pegvisomant.
The Journal of clinical endocrinology and metabolism 2008;93(9):3515-8.
2008: Zhou Cuiqi; Tong Yunguang; Wawrowsky Kolja; Bannykh Serguei; Donangelo Ines; Melmed Shlomo
Oct-1 induces pituitary tumor transforming gene expression in endocrine tumors.
Endocrine-related cancer 2008;15(3):817-31.
2008: Vlotides George; Siegel Emily; Donangelo Ines; Gutman Shiri; Ren Song-Guang; Melmed Shlomo
Rat prolactinoma cell growth regulation by epidermal growth factor receptor ligands.
Cancer research 2008;68(15):6377-86.
2008: Murray Robert D; Melmed Shlomo
A critical analysis of clinically available somatostatin analog formulations for therapy of acromegaly.
The Journal of clinical endocrinology and metabolism 2008;93(8):2957-68.
2008: Liu Ning-Ai; Ren Meina; Song Jianbo; Ríos Yesenia; Wawrowsky Kolja; Ben-Shlomo Anat; Lin Shuo; Melmed Shlomo
In vivo time-lapse imaging delineates the zebrafish pituitary proopiomelanocortin lineage boundary regulated by FGF3 signal.
Developmental biology 2008;319(2):192-200.
2008: Ben-Shlomo Anat; Melmed Shlomo
Somatostatin agonists for treatment of acromegaly.
Molecular and cellular endocrinology 2008;286(1-2):192-8.
2008: Cooper Odelia; Geller Jordan L; Melmed Shlomo
Ovarian hyperstimulation syndrome caused by an FSH-secreting pituitary adenoma.
Nature clinical practice. Endocrinology & metabolism 2008;4(4):234-8.
2008: Melmed Gil Y; Devlin Shane M; Vlotides George; Dhall Deepti; Ross Soraya; Yu Run; Melmed Shlomo
Anti-aging therapy with human growth hormone associated with metastatic colon cancer in a patient with Crohn's colitis.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2008;6(3):360-3.
2008: Ben-Shlomo Anat; Melmed Shlomo
Acromegaly.
Endocrinology and metabolism clinics of North America 2008;37(1):101-22, viii.
2008: Melmed Shlomo
Update in pituitary disease.
The Journal of clinical endocrinology and metabolism 2008;93(2):331-8.
2007: Ben-Shlomo Anat; Melmed Shlomo
Pasireotide--a somatostatin analog for the potential treatment of acromegaly, neuroendocrine tumors and Cushing's disease.
IDrugs : the investigational drugs journal 2007;10(12):885-95.
2007: Gruszka Anna; Ren Song-Guang; Dong Jesse; Culler Michael D; Melmed Shlomo
Regulation of growth hormone and prolactin gene expression and secretion by chimeric somatostatin-dopamine molecules.
Endocrinology 2007;148(12):6107-14.
2007: Chesnokova Vera; Zonis Svetlana; Rubinek Tami; Yu Run; Ben-Shlomo Anat; Kovacs Kalman; Wawrowsky Kolja; Melmed Shlomo
Senescence mediates pituitary hypoplasia and restrains pituitary tumor growth.
Cancer research 2007;67(21):10564-72.
2007: Ben-Shlomo Anat; Pichurin Oxana; Barshop Nicole J; Wawrowsky Kolja A; Taylor John; Culler Michael D; Chesnokova Vera; Liu Ning-Ai; Melmed Shlomo
Selective regulation of somatostatin receptor subtype signaling: evidence for constitutive receptor activation.
Molecular endocrinology (Baltimore, Md.) 2007;21(10):2565-78.
2007: Rubinek Tami; Chesnokova Vera; Wolf Ido; Wawrowsky Kolja; Vlotides George; Melmed Shlomo
Discordant proliferation and differentiation in pituitary tumor-transforming gene-null bone marrow stem cells.
American journal of physiology. Cell physiology 2007;293(3):C1082-92.
2007: Tong Y; Tan Y; Zhou C; Melmed S
Pituitary tumor transforming gene interacts with Sp1 to modulate G1/S cell phase transition.
Oncogene 2007;26(38):5596-605.
2007: Melmed Shlomo
Aryl hydrocarbon receptor interacting protein and pituitary tumorigenesis: another interesting protein.
The Journal of clinical endocrinology and metabolism 2007;92(5):1617-9.
2007: Vlotides George; Eigler Tamar; Melmed Shlomo
Pituitary tumor-transforming gene: physiology and implications for tumorigenesis.
Endocrine reviews 2007;28(2):165-86.
2006: Melmed Shlomo
Medical progress: Acromegaly.
The New England journal of medicine 2006;355(24):2558-73.
2006: Yu Run; Bonert Vivien; Saporta Inbar; Raffel Leslie J; Melmed Shlomo
Aryl hydrocarbon receptor interacting protein variants in sporadic pituitary adenomas.
The Journal of clinical endocrinology and metabolism 2006;91(12):5126-9.
2006: Vlotides G; Cruz-Soto M; Rubinek T; Eigler T; Auernhammer C J; Melmed S
Mechanisms for growth factor-induced pituitary tumor transforming gene-1 expression in pituitary folliculostellate TtT/GF cells.
Molecular endocrinology (Baltimore, Md.) 2006;20(12):3321-35.
2006: Yu Run; Cruz-Soto Martha; Li Calzi Sergio; Hui Hongxiang; Melmed Shlomo
Murine pituitary tumor-transforming gene functions as a securin protein in insulin-secreting cells.
The Journal of endocrinology 2006;191(1):45-53.
2006: Donangelo Ines; Gutman Shiri; Horvath Eva; Kovacs Kalman; Wawrowsky Kolja; Mount Michael; Melmed Shlomo
Pituitary tumor transforming gene overexpression facilitates pituitary tumor development.
Endocrinology 2006;147(10):4781-91.
2006: Ren Song-Guang; Melmed Shlomo
Pyridoxal phosphate inhibits pituitary cell proliferation and hormone secretion.
Endocrinology 2006;147(8):3936-42.
2006: Bonert Vivien S; Melmed Shlomo
Acromegaly with moderate hyperprolactinemia caused by an intrasellar macroadenoma.
Nature clinical practice. Endocrinology & metabolism 2006;2(7):408-12; quiz following 412.
2006: Ben-Shlomo Anat; Melmed Shlomo
Skin manifestations in acromegaly.
Clinics in dermatology 2006;24(4):256-9.
2006: Fraenkel M; Caloyeras J; Ren S-G; Melmed S
Sex-steroid milieu determines diabetes rescue in pttg-null mice.
The Journal of endocrinology 2006;189(3):519-28.
2006: Lum Pek Yee; Chen Yanqing; Zhu Jun; Lamb John; Melmed Shlomo; Wang Susanna; Drake Tom A; Lusis Aldons J; Schadt Eric E
Elucidating the murine brain transcriptional network in a segregating mouse population to identify core functional modules for obesity and diabetes.
Journal of neurochemistry 2006;97 Suppl 1():50-62.
2006: Liu Ning-Ai; Liu Qian; Wawrowsky Kolja; Yang Zhongan; Lin Shuo; Melmed Shlomo
Prolactin receptor signaling mediates the osmotic response of embryonic zebrafish lactotrophs.
Molecular endocrinology (Baltimore, Md.) 2006;20(4):871-80.
2006: Melmed Shlomo
Supplemental growth hormone in healthy adults: the endocrinologist's responsibility.
Nature clinical practice. Endocrinology & metabolism 2006;2(3):119.
2006: Akita Sadanori; Akino Kozo; Ren Song Guang; Melmed Shlomo; Imaizumi Toshifumi; Hirano Akiyoshi
Elevated circulating leukemia inhibitory factor in patients with extensive burns.
Journal of burn care & research : official publication of the American Burn Association 2006;27(2):221-5.
2006: Yu Run; Bonert Vivien; Cruz-Soto Martha; Melmed Shlomo
Cyclin-dependent kinase inhibitor gene polymorphisms in pituitary gigantism.
Endocrine 2006;29(1):119-20.
2006: Gillingwater Thomas H; Wishart Thomas M; Chen Philip E; Haley Jane E; Robertson Kevin; MacDonald Stephen H-F; Middleton Susan; Wawrowski Kolja; Shipston Michael J; Melmed Shlomo; Wyllie David J A; Skehel Paul A; Coleman Michael P; Ribchester Richard R
The neuroprotective WldS gene regulates expression of PTTG1 and erythroid differentiation regulator 1-like gene in mice and human cells.
Human molecular genetics 2006;15(4):625-35.
2006: Melmed Shlomo
2004 World Health Organization classification of pituitary tumors: what is new?
Acta neuropathologica 2006;111(1):78-9.
2006: Donangelo Ines; Melmed Shlomo
Implication of pituitary tropic status on tumor development.
Frontiers of hormone research 2006;35():1-8.
2005: Melmed S; Casanueva F; Cavagnini F; Chanson P; Frohman L A; Gaillard R; Ghigo E; Ho K; Jaquet P; Kleinberg D; Lamberts S; Laws E; Lombardi G; Sheppard M C; Thorner M; Vance M L; Wass J A H; Giustina A
Consensus statement: medical management of acromegaly.
European journal of endocrinology / European Federation of Endocrine Societies 2005;153(6):737-40.
2005: Akino Kozo; Akita Sadanori; Mizuguchi Toru; Takumi Ichiro; Yu Run; Wang Xhi-yong; Rozga Jacek; Demetriou Achilles A; Melmed Shlomo; Ohtsuru Akira; Yamashita Shunichi
A novel molecular marker of pituitary tumor transforming gene involves in a rat liver regeneration.
The Journal of surgical research 2005;129(1):142-6.
2005: Bronstein Marcello D; Melmed Shlomo
[Pituitary tumorigenesis]
Arquivos brasileiros de endocrinologia e metabologia 2005;49(5):615-25.
2005: Donangelo Ines; Melmed Shlomo
Treatment of acromegaly: future.
Endocrine 2005;28(1):123-8.
2005: Chesnokova Vera; Kovacs Kalman; Castro Anna-Valeria; Zonis Svetlana; Melmed Shlomo
Pituitary hypoplasia in Pttg-/- mice is protective for Rb+/- pituitary tumorigenesis.
Molecular endocrinology (Baltimore, Md.) 2005;19(9):2371-9.
2005: Melmed Shlomo; Sternberg Richard; Cook David; Klibanski Anne; Chanson Philippe; Bonert Vivien; Vance Mary Lee; Rhew David; Kleinberg David; Barkan Ariel
A critical analysis of pituitary tumor shrinkage during primary medical therapy in acromegaly.
The Journal of clinical endocrinology and metabolism 2005;90(7):4405-10.
2005: Ben-Shlomo Anat; Wawrowsky Kolja A; Proekt Irina; Wolkenfeld Nathaniel M; Ren Song-Guang; Taylor John; Culler Michael D; Melmed Shlomo
Somatostatin receptor type 5 modulates somatostatin receptor type 2 regulation of adrenocorticotropin secretion.
The Journal of biological chemistry 2005;280(25):24011-21.
2005: Abbud Rula A; Takumi Ichiro; Barker Erin M; Ren Song-Guang; Chen Dar-Yong; Wawrowsky Kolja; Melmed Shlomo
Early multipotential pituitary focal hyperplasia in the alpha-subunit of glycoprotein hormone-driven pituitary tumor-transforming gene transgenic mice.
Molecular endocrinology (Baltimore, Md.) 2005;19(5):1383-91.
2005: Donangelo I; Melmed S
Pathophysiology of pituitary adenomas.
Journal of endocrinological investigation 2005;28(11 Suppl International):100-5.
2004: Murray Robert D; Kim Kiwon; Ren Song-Guang; Chelly Marjorie; Umehara Yutaka; Melmed Shlomo
Central and peripheral actions of somatostatin on the growth hormone-IGF-I axis.
The Journal of clinical investigation 2004;114(3):349-56.
2004: Bonert Vivien S; Elashoff Janet D; Barnett Philip; Melmed Shlomo
Body mass index determines evoked growth hormone (GH) responsiveness in normal healthy male subjects: diagnostic caveat for adult GH deficiency.
The Journal of clinical endocrinology and metabolism 2004;89(7):3397-401.
2004: Murray Robert D; Kim Kiwon; Ren Song-Guang; Lewis Ian; Weckbecker Gisbert; Bruns Christian; Melmed Shlomo
The novel somatostatin ligand (SOM230) regulates human and rat anterior pituitary hormone secretion.
The Journal of clinical endocrinology and metabolism 2004;89(6):3027-32.
2004: Heaney Anthony P; Melmed Shlomo
Molecular targets in pituitary tumours.
Nature reviews. Cancer 2004;4(4):285-95.
2004: Abbud Rula A; Kelleher Robert; Melmed Shlomo
Cell-specific pituitary gene expression profiles after treatment with leukemia inhibitory factor reveal novel modulators for proopiomelanocortin expression.
Endocrinology 2004;145(2):867-80.
2004: Yu Run; Melmed Shlomo
Pituitary tumor transforming gene: an update.
Frontiers of hormone research 2004;32():175-85.
2003: Giustina A; Casanueva F F; Cavagnini F; Chanson P; Clemmons D; Frohman L A; Gaillard R; Ho K; Jaquet P; Kleinberg D L; Lamberts S W J; Lombardi G; Sheppard M; Strasburger C J; Vance M L; Wass J A H; Melmed S;
Diagnosis and treatment of acromegaly complications.
Journal of endocrinological investigation 2003;26(12):1242-7.
2003: Melmed Shlomo
Mechanisms for pituitary tumorigenesis: the plastic pituitary.
The Journal of clinical investigation 2003;112(11):1603-18.
2003: Ren Song-Guang; Kim Sun; Taylor John; Dong Josse; Moreau Jacques-Pierre; Culler Michael D; Melmed Shlomo
Suppression of rat and human growth hormone and prolactin secretion by a novel somatostatin/dopaminergic chimeric ligand.
The Journal of clinical endocrinology and metabolism 2003;88(11):5414-21.
2003: Yu Run; Lu Wenge; Chen Jiandong; McCabe Chris J; Melmed Shlomo
Overexpressed pituitary tumor-transforming gene causes aneuploidy in live human cells.
Endocrinology 2003;144(11):4991-8.
2003: Turner Helen E; Harris Adrian L; Melmed Shlomo; Wass John A H
Angiogenesis in endocrine tumors.
Endocrine reviews 2003;24(5):600-32.
2003: Clemmons David R; Chihara Kazuo; Freda Pamela U; Ho Ken K Y; Klibanski Anne; Melmed Shlomo; Shalet Stephen M; Strasburger Christian J; Trainer Peter J; Thorner Michael O
Optimizing control of acromegaly: integrating a growth hormone receptor antagonist into the treatment algorithm.
The Journal of clinical endocrinology and metabolism 2003;88(10):4759-67.
2003: Ren Song-Guang; Taylor John; Dong Jesse; Yu Run; Culler Michael D; Melmed Shlomo
Functional association of somatostatin receptor subtypes 2 and 5 in inhibiting human growth hormone secretion.
The Journal of clinical endocrinology and metabolism 2003;88(9):4239-45.
2003: Rubinek Tami; Yu Run; Hadani Moshe; Barkai Gad; Nass Dvora; Melmed Shlomo; Shimon Ilan
The cell adhesion molecules N-cadherin and neural cell adhesion molecule regulate human growth hormone: a novel mechanism for regulating pituitary hormone secretion.
The Journal of clinical endocrinology and metabolism 2003;88(8):3724-30.
2003: Heaney Anthony P; Fernando Manory; Melmed Shlomo
PPAR-gamma receptor ligands: novel therapy for pituitary adenomas.
The Journal of clinical investigation 2003;111(9):1381-8.
2003: Liu Ning-Ai; Huang Haigen; Yang Zhongan; Herzog Wiebke; Hammerschmidt Matthias; Lin Shuo; Melmed Shlomo
Pituitary corticotroph ontogeny and regulation in transgenic zebrafish.
Molecular endocrinology (Baltimore, Md.) 2003;17(5):959-66.
2003: Giustina Andrea; Melmed Shlomo
Acromegaly consensus: the next steps.
The Journal of clinical endocrinology and metabolism 2003;88(4):1913-4.
2003: Horwitz Gregory A; Miklovsky Irina; Heaney Anthony P; Ren Song-Guang; Melmed Shlomo
Human pituitary tumor-transforming gene (PTTG1) motif suppresses prolactin expression.
Molecular endocrinology (Baltimore, Md.) 2003;17(4):600-9.
2003: Ben-Shlomo Anat; Melmed Shlomo
Clinical review 154: The role of pharmacotherapy in perioperative management of patients with acromegaly.
The Journal of clinical endocrinology and metabolism 2003;88(3):963-8.
2003: Wang Zhiyong; Moro Enrico; Kovacs Kalman; Yu Run; Melmed Shlomo
Pituitary tumor transforming gene-null male mice exhibit impaired pancreatic beta cell proliferation and diabetes.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(6):3428-32.
2003: Ben-Shlomo Anat; Miklovsky Irina; Ren Song-Guang; Yong William H; Heaney Anthony P; Culler Michael D; Melmed Shlomo
Leukemia inhibitory factor regulates prolactin secretion in prolactinoma and lactotroph cells.
The Journal of clinical endocrinology and metabolism 2003;88(2):858-63.
2002: Stoika Rostyslav; Melmed Shlomo
Expression and function of pituitary tumour transforming gene for T-lymphocyte activation.
British journal of haematology 2002;119(4):1070-4.
2002: Heaney Anthony P; Fernando Manory; Yong William H; Melmed Shlomo
Functional PPAR-gamma receptor is a novel therapeutic target for ACTH-secreting pituitary adenomas.
Nature medicine 2002;8(11):1281-7.
2002: Melmed S; Casanueva F F; Cavagnini F; Chanson P; Frohman L; Grossman A; Ho K; Kleinberg D; Lamberts S; Laws E; Lombardi G; Vance M L; Werder K Von; Wass J; Giustina A;
Guidelines for acromegaly management.
The Journal of clinical endocrinology and metabolism 2002;87(9):4054-8.
2002: Yu R; Ren S-G; Melmed S
Proteasome inhibitors induce apoptosis in growth hormone- and prolactin-secreting rat pituitary tumor cells.
The Journal of endocrinology 2002;174(3):379-86.
2002: Chesnokova Vera; Melmed Shlomo
Minireview: Neuro-immuno-endocrine modulation of the hypothalamic-pituitary-adrenal (HPA) axis by gp130 signaling molecules.
Endocrinology 2002;143(5):1571-4.
2002: Chesnokova Vera; Kariagina Anastasia; Melmed Shlomo
Opposing effects of pituitary leukemia inhibitory factor and SOCS-3 on the ACTH axis response to inflammation.
American journal of physiology. Endocrinology and metabolism 2002;282(5):E1110-8.
2002: Heaney Anthony P; Fernando Manory; Melmed Shlomo
Functional role of estrogen in pituitary tumor pathogenesis.
The Journal of clinical investigation 2002;109(2):277-83.
2002: Melmed Shlomo; Vance Mary Lee; Barkan Ariel L; Bengtsson Bengt-Ake; Kleinberg David; Klibanski Anne; Trainer Peter J
Current status and future opportunities for controlling acromegaly.
Pituitary 2002;5(3):185-96.
2001: Melmed S
Series introduction. The immuno-neuroendocrine interface.
The Journal of clinical investigation 2001;108(11):1563-6.
2001: van der Lely A J; Hutson R K; Trainer P J; Besser G M; Barkan A L; Katznelson L; Klibanski A; Herman-Bonert V; Melmed S; Vance M L; Freda P U; Stewart P M; Friend K E; Clemmons D R; Johannsson G; Stavrou S; Cook D M; Phillips L S; Strasburger C J; Hackett S; Zib K A; Davis R J; Scarlett J A; Thorner M O
Long-term treatment of acromegaly with pegvisomant, a growth hormone receptor antagonist.
Lancet 2001;358(9295):1754-9.
2001: Bousquet C; Chesnokova V; Kariagina A; Ferrand A; Melmed S
cAMP neuropeptide agonists induce pituitary suppressor of cytokine signaling-3: novel negative feedback mechanism for corticotroph cytokine action.
Molecular endocrinology (Baltimore, Md.) 2001;15(11):1880-90.
2001: Wang Z; Yu R; Melmed S
Mice lacking pituitary tumor transforming gene show testicular and splenic hypoplasia, thymic hyperplasia, thrombocytopenia, aberrant cell cycle progression, and premature centromere division.
Molecular endocrinology (Baltimore, Md.) 2001;15(11):1870-9.
2001: Ben-Shlomo A; Melmed S
Acromegaly.
Endocrinology and metabolism clinics of North America 2001;30(3):565-83, vi.
2001: Melmed S
Acromegaly and cancer: not a problem?
The Journal of clinical endocrinology and metabolism 2001;86(7):2929-34.
2001: Yu R; Melmed S
Oncogene activation in pituitary tumors.
Brain pathology (Zurich, Switzerland) 2001;11(3):328-41.
2001: Rubinek T; Hadani M; Barkai G; Melmed S; Shimon I
Prolactin (PRL)-releasing peptide stimulates PRL secretion from human fetal pituitary cultures and growth hormone release from cultured pituitary adenomas.
The Journal of clinical endocrinology and metabolism 2001;86(6):2826-30.
2001: Ishikawa H; Heaney A P; Yu R; Horwitz G A; Melmed S
Human pituitary tumor-transforming gene induces angiogenesis.
The Journal of clinical endocrinology and metabolism 2001;86(2):867-74.
2000: Bousquet C; Zatelli M C; Melmed S
Direct regulation of pituitary proopiomelanocortin by STAT3 provides a novel mechanism for immuno-neuroendocrine interfacing.
The Journal of clinical investigation 2000;106(11):1417-25.
2000: Chesnokova V; Melmed S
Leukemia inhibitory factor mediates the hypothalamic pituitary adrenal axis response to inflammation.
Endocrinology 2000;141(11):4032-40.
2000: Yu R; Heaney A P; Lu W; Chen J; Melmed S
Pituitary tumor transforming gene causes aneuploidy and p53-dependent and p53-independent apoptosis.
The Journal of biological chemistry 2000;275(47):36502-5.
2000: Maheshwari H G; Prezant T R; Herman-Bonert V; Shahinian H; Kovacs K; Melmed S
Long-acting peptidomimergic control of gigantism caused by pituitary acidophilic stem cell adenoma.
The Journal of clinical endocrinology and metabolism 2000;85(9):3409-16.
2000: Herman-Bonert V S; Zib K; Scarlett J A; Melmed S
Growth hormone receptor antagonist therapy in acromegalic patients resistant to somatostatin analogs.
The Journal of clinical endocrinology and metabolism 2000;85(8):2958-61.
2000: Yu R; Ren S G; Horwitz G A; Wang Z; Melmed S
Pituitary tumor transforming gene (PTTG) regulates placental JEG-3 cell division and survival: evidence from live cell imaging.
Molecular endocrinology (Baltimore, Md.) 2000;14(8):1137-46.
2000: Heaney A P; Melmed S
New pituitary oncogenes.
Endocrine-related cancer 2000;7(1):3-15.
2000: Wang Z; Melmed S
Pituitary tumor transforming gene (PTTG) transforming and transactivation activity.
The Journal of biological chemistry 2000;275(11):7459-61.
2000: Heaney A P; Singson R; McCabe C J; Nelson V; Nakashima M; Melmed S
Expression of pituitary-tumour transforming gene in colorectal tumours.
Lancet 2000;355(9205):716-9.
2000: Giustina A; Barkan A; Casanueva F F; Cavagnini F; Frohman L; Ho K; Veldhuis J; Wass J; Von Werder K; Melmed S
Criteria for cure of acromegaly: a consensus statement.
The Journal of clinical endocrinology and metabolism 2000;85(2):526-9.
2000: Wang Z; Melmed S
Characterization of the murine pituitary tumor transforming gene (PTTG) and its promoter.
Endocrinology 2000;141(2):763-71.
2000: Drange M R; Fram N R; Herman-Bonert V; Melmed S
Pituitary tumor registry: a novel clinical resource.
The Journal of clinical endocrinology and metabolism 2000;85(1):168-74.
2000: Auernhammer C J; Bousquet C; Chesnokova V; Melmed S
SOCS proteins: modulators of neuroimmunoendocrine functions. Impact on corticotroph LIF signaling.
Annals of the New York Academy of Sciences 2000;917():658-64.
1999: Heaney A P; Horwitz G A; Wang Z; Singson R; Melmed S
Early involvement of estrogen-induced pituitary tumor transforming gene and fibroblast growth factor expression in prolactinoma pathogenesis.
Nature medicine 1999;5(11):1317-21.
1999: Bousquet C; Susini C; Melmed S
Inhibitory roles for SHP-1 and SOCS-3 following pituitary proopiomelanocortin induction by leukemia inhibitory factor.
The Journal of clinical investigation 1999;104(9):1277-85.
1999: Heaney A P; Melmed S
Pituitary tumour transforming gene: a novel factor in pituitary tumour formation.
Baillière's best practice & research. Clinical endocrinology & metabolism 1999;13(3):367-80.
1999: Ren S G; Seliktar J; Li X; Hershman J M; Braunstein G D; Melmed S
In vivo and in vitro regulation of thyroid leukemia inhibitory factor (LIF): marker of hypothyroidism.
The Journal of clinical endocrinology and metabolism 1999;84(8):2883-7.
1999: Drange M R; Melmed S
Molecular pathogenesis of acromegaly.
Pituitary 1999;2(1):43-50.
1999: Auernhammer C J; Bousquet C; Melmed S
Autoregulation of pituitary corticotroph SOCS-3 expression: characterization of the murine SOCS-3 promoter.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(12):6964-9.
1999: Bousquet C; Melmed S
Critical role for STAT3 in murine pituitary adrenocorticotropin hormone leukemia inhibitory factor signaling.
The Journal of biological chemistry 1999;274(16):10723-30.
1999: Auernhammer C J; Melmed S
Interleukin-11 stimulates proopiomelanocortin gene expression and adrenocorticotropin secretion in corticotroph cells: evidence for a redundant cytokine network in the hypothalamo-pituitary-adrenal axis.
Endocrinology 1999;140(4):1559-66.
1999: Melmed S
Pathogenesis of pituitary tumors.
Endocrinology and metabolism clinics of North America 1999;28(1):1-12, v.
1999: Prezant T R; Kadioglu P; Melmed S
An intronless homolog of human proto-oncogene hPTTG is expressed in pituitary tumors: evidence for hPTTG family.
The Journal of clinical endocrinology and metabolism 1999;84(3):1149-52.
1999: Zhang X; Horwitz G A; Heaney A P; Nakashima M; Prezant T R; Bronstein M D; Melmed S
Pituitary tumor transforming gene (PTTG) expression in pituitary adenomas.
The Journal of clinical endocrinology and metabolism 1999;84(2):761-7.
1999: Zhang X; Horwitz G A; Prezant T R; Valentini A; Nakashima M; Bronstein M D; Melmed S
Structure, expression, and function of human pituitary tumor-transforming gene (PTTG).
Molecular endocrinology (Baltimore, Md.) 1999;13(1):156-66.
1998: Yano H; Readhead C; Nakashima M; Ren S G; Melmed S
Pituitary-directed leukemia inhibitory factor transgene causes Cushing's syndrome: neuro-immune-endocrine modulation of pituitary development.
Molecular endocrinology (Baltimore, Md.) 1998;12(11):1708-20.
1998: Shimon I; Yan X; Magoffin D A; Friedman T C; Melmed S
Intact leptin receptor is selectively expressed in human fetal pituitary and pituitary adenomas and signals human fetal pituitary growth hormone secretion.
The Journal of clinical endocrinology and metabolism 1998;83(11):4059-64.
1998: Wang Z; Melmed S
Functional map of a placenta-specific enhancer of the human leukemia inhibitory factor receptor gene.
The Journal of biological chemistry 1998;273(40):26069-77.
1998: Drange M R; Melmed S
Long-acting lanreotide induces clinical and biochemical remission of acromegaly caused by disseminated growth hormone-releasing hormone-secreting carcinoid.
The Journal of clinical endocrinology and metabolism 1998;83(9):3104-9.
1998: Newman C B; Melmed S; George A; Torigian D; Duhaney M; Snyder P; Young W; Klibanski A; Molitch M E; Gagel R; Sheeler L; Cook D; Malarkey W; Jackson I; Vance M L; Barkan A; Frohman L; Kleinberg D L
Octreotide as primary therapy for acromegaly.
The Journal of clinical endocrinology and metabolism 1998;83(9):3034-40.
1998: Shimon I; Melmed S
Management of pituitary tumors.
Annals of internal medicine 1998;129(6):472-83.
1998: Melmed S; Jackson I; Kleinberg D; Klibanski A
Current treatment guidelines for acromegaly.
The Journal of clinical endocrinology and metabolism 1998;83(8):2646-52.
1998: Auernhammer C J; Chesnokova V; Bousquet C; Melmed S
Pituitary corticotroph SOCS-3: novel intracellular regulation of leukemia-inhibitory factor-mediated proopiomelanocortin gene expression and adrenocorticotropin secretion.
Molecular endocrinology (Baltimore, Md.) 1998;12(7):954-61.
1998: Melmed S
gp130-Related Cytokines and Their Receptors in the Pituitary.
Trends in endocrinology and metabolism: TEM 1998;9(4):155-61.
1998: Takeuchi S; Koeffler H P; Hinton D R; Miyoshi I; Melmed S; Shimon I
Mutation and expression analysis of the cyclin-dependent kinase inhibitor gene p27/Kip1 in pituitary tumors.
The Journal of endocrinology 1998;157(2):337-41.
1998: Ray D W; Ren S G; Melmed S
Leukemia inhibitory factor regulates proopiomelanocortin transcription.
Annals of the New York Academy of Sciences 1998;840():162-73.
1998: Chesnokova V; Auernhammer C J; Melmed S
Murine leukemia inhibitory factor gene disruption attenuates the hypothalamo-pituitary-adrenal axis stress response.
Endocrinology 1998;139(5):2209-16.
1998: Auernhammer C J; Chesnokova V; Melmed S
Leukemia inhibitory factor modulates interleukin-1beta-induced activation of the hypothalamo-pituitary-adrenal axis.
Endocrinology 1998;139(5):2201-8.
1998: Prezant T R; Levine J; Melmed S
Molecular characterization of the men1 tumor suppressor gene in sporadic pituitary tumors.
The Journal of clinical endocrinology and metabolism 1998;83(4):1388-91.
1998: Ren S G; Seliktar J; Li X; Braunstein G D; Melmed S
Measurement of leukemia inhibitory factor in biological fluids by radioimmunoassay.
The Journal of clinical endocrinology and metabolism 1998;83(4):1275-83.
1998: Herman-Bonert V; Seliverstov M; Melmed S
Pregnancy in acromegaly: successful therapeutic outcome.
The Journal of clinical endocrinology and metabolism 1998;83(3):727-31.
1998: Shimon I; Hinton D R; Weiss M H; Melmed S
Prolactinomas express human heparin-binding secretory transforming gene (hst) protein product: marker of tumour invasiveness.
Clinical endocrinology 1998;48(1):23-9.
1998: Shimon I; Yan X; Melmed S
Human fetal pituitary expresses functional growth hormone-releasing peptide receptors.
The Journal of clinical endocrinology and metabolism 1998;83(1):174-8.
1997: Melmed S
gp130-Related Cytokines and Their Receptors in the Pituitary.
Trends in endocrinology and metabolism: TEM 1997;8(10):391-7.
1997: Li Q L; Yano H; Ren S G; Li X; Friedman T C; Melmed S
Leukemia inhibitory factor (LIF) modulates pro-opiomelanocortin (POMC) gene regulation in stably transfected AtT-20 cells overexpressing LIF.
Endocrine 1997;7(3):325-30.
1997: Shimon I; Yan X; Taylor J E; Weiss M H; Culler M D; Melmed S
Somatostatin receptor (SSTR) subtype-selective analogues differentially suppress in vitro growth hormone and prolactin in human pituitary adenomas. Novel potential therapy for functional pituitary tumors.
The Journal of clinical investigation 1997;100(9):2386-92.
1997: Shimon I; Melmed S
Structure and function of somatostatin receptors in growth hormone control.
The Journal of endocrinology 1997;155 Suppl 1():S3-6; discussion S7-8.
1997: Wang Z; Melmed S
Identification of an upstream enhancer within a functional promoter of the human leukemia inhibitory factor receptor gene and its alternative promoter usage.
The Journal of biological chemistry 1997;272(44):27957-65.
1997: Shimon I; Yan X; Ray D W; Melmed S
Cytokine-dependent gp130 receptor subunit regulates human fetal pituitary adrenocorticotropin hormone and growth hormone secretion.
The Journal of clinical investigation 1997;100(2):357-63.
1997: Ren S G; Melmed S; Braunstein G D
Decidual leukemia inhibitory factor production and action on human chorionic gonadotropin secretion at different stages of gestation in vitro.
Early pregnancy : biology and medicine : the official journal of the Society for the Investigation of Early Pregnancy 1997;3(2):102-8.
1997: Shimon I; Melmed S
Genetic basis of endocrine disease: pituitary tumor pathogenesis.
The Journal of clinical endocrinology and metabolism 1997;82(6):1675-81.
1997: Akita S; Readhead C; Stefaneanu L; Fine J; Tampanaru-Sarmesiu A; Kovacs K; Melmed S
Pituitary-directed leukemia inhibitory factor transgene forms Rathke's cleft cysts and impairs adult pituitary function. A model for human pituitary Rathke's cysts.
The Journal of clinical investigation 1997;99(10):2462-9.
1997: Ray D; Melmed S
Pituitary cytokine and growth factor expression and action.
Endocrine reviews 1997;18(2):206-28.
1997: Bousquet C; Ray D W; Melmed S
A common pro-opiomelanocortin-binding element mediates leukemia inhibitory factor and corticotropin-releasing hormone transcriptional synergy.
The Journal of biological chemistry 1997;272(16):10551-7.
1997: Pei L; Melmed S
Isolation and characterization of a pituitary tumor-transforming gene (PTTG).
Molecular endocrinology (Baltimore, Md.) 1997;11(4):433-41.
1997: Shimon I; Taylor J E; Dong J Z; Bitonte R A; Kim S; Morgan B; Coy D H; Culler M D; Melmed S
Somatostatin receptor subtype specificity in human fetal pituitary cultures. Differential role of SSTR2 and SSTR5 for growth hormone, thyroid-stimulating hormone, and prolactin regulation.
The Journal of clinical investigation 1997;99(4):789-98.
1997: Shimon I; Melmed S
Growth hormone- and growth-hormone-releasing hormone-producing tumors.
Cancer treatment and research 1997;89():1-24.
1996: Akita S; Conn P M; Melmed S
Leukemia inhibitory factor (LIF) induces acute adrenocorticotrophic hormone (ACTH) secretion in fetal rhesus macaque primates: a novel dynamic test of pituitary function.
The Journal of clinical endocrinology and metabolism 1996;81(11):4170-8.
1996: Shohat M; Tick D; Barakat S; Bu X; Melmed S; Rimoin D L
Short-term recombinant human growth hormone treatment increases growth rate in achondroplasia.
The Journal of clinical endocrinology and metabolism 1996;81(11):4033-7.
1996: Melmed S
Molecular pathophysiology of acromegaly.
Acta paediatrica (Oslo, Norway : 1992). Supplement 1996;417():45-8.
1996: Stefana B; Ray D W; Melmed S
Leukemia inhibitory factor induces differentiation of pituitary corticotroph function: an immuno-neuroendocrine phenotypic switch.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(22):12502-6.
1996: Melmed S
Acromegaly.
Metabolism: clinical and experimental 1996;45(8 Suppl 1):51-2.
1996: Akita S; Malkin J; Melmed S
Disrupted murine leukemia inhibitory factor (LIF) gene attenuates adrenocorticotropic hormone (ACTH) secretion.
Endocrinology 1996;137(7):3140-3.
1996: Wang Z; Ren S G; Melmed S
Hypothalamic and pituitary leukemia inhibitory factor gene expression in vivo: a novel endotoxin-inducible neuro-endocrine interface.
Endocrinology 1996;137(7):2947-53.
1996: Melmed S
Unwanted effects of growth hormone excess in the adult.
Journal of pediatric endocrinology & metabolism : JPEM 1996;9 Suppl 3():369-74.
1996: Ray D W; Ren S G; Melmed S
Leukemia inhibitory factor (LIF) stimulates proopiomelanocortin (POMC) expression in a corticotroph cell line. Role of STAT pathway.
The Journal of clinical investigation 1996;97(8):1852-9.
1996: Shimon I; Hüttner A; Said J; Spirina O M; Melmed S
Heparin-binding secretory transforming gene (hst) facilitates rat lactotrope cell tumorigenesis and induces prolactin gene transcription.
The Journal of clinical investigation 1996;97(1):187-95.
1996: Melmed S; Yamashita S; Yamasaki H; Fagin J; Namba H; Yamamoto H; Weber M; Morita S; Webster J; Prager D
IGF-I receptor signalling: lessons from the somatotroph.
Recent progress in hormone research 1996;51():189-215; discussion 215-6.
1995: Newman C B; Melmed S; Snyder P J; Young W F; Boyajy L D; Levy R; Stewart W N; Klibanski A; Molitch M E; Gagel R F
Safety and efficacy of long-term octreotide therapy of acromegaly: results of a multicenter trial in 103 patients--a clinical research center study.
The Journal of clinical endocrinology and metabolism 1995;80(9):2768-75.
1995: Takino H; Herman V; Weiss M; Melmed S
Purine-binding factor (nm23) gene expression in pituitary tumors: marker of adenoma invasiveness.
The Journal of clinical endocrinology and metabolism 1995;80(5):1733-8.
1995: Pei L; Melmed S; Scheithauer B; Kovacs K; Benedict W F; Prager D
Frequent loss of heterozygosity at the retinoblastoma susceptibility gene (RB) locus in aggressive pituitary tumors: evidence for a chromosome 13 tumor suppressor gene other than RB.
Cancer research 1995;55(8):1613-6.
1995: Akita S; Webster J; Ren S G; Takino H; Said J; Zand O; Melmed S
Human and murine pituitary expression of leukemia inhibitory factor. Novel intrapituitary regulation of adrenocorticotropin hormone synthesis and secretion.
The Journal of clinical investigation 1995;95(3):1288-98.
1995: Greenman Y; Prager D; Melmed S
The IGF-I receptor sub-membrane domain is intact in GH-secreting pituitary tumours.
Clinical endocrinology 1995;42(2):169-72.
1994: Greenman Y; Melmed S
Expression of three somatostatin receptor subtypes in pituitary adenomas: evidence for preferential SSTR5 expression in the mammosomatotroph lineage.
The Journal of clinical endocrinology and metabolism 1994;79(3):724-9.
1994: Prager D; Yamasaki H; Weber M M; Melmed S
Role of the insulin-like growth factors in regulating neuroendocrine function.
Neurobiology of aging 1994;15(4):569-72.
1994: Webster J; Prager D; Melmed S
Insulin-like growth factor-1 activation of extracellular signal-related kinase-1 and -2 in growth hormone-secreting cells.
Molecular endocrinology (Baltimore, Md.) 1994;8(5):539-44.
1994: Prager D; Li H L; Yamasaki H; Melmed S
Human insulin-like growth factor I receptor internalization. Role of the juxtamembrane domain.
The Journal of biological chemistry 1994;269(16):11934-7.
1994: Pei L; Melmed S; Scheithauer B; Kovacs K; Prager D
H-ras mutations in human pituitary carcinoma metastases.
The Journal of clinical endocrinology and metabolism 1994;78(4):842-6.
1994: Prager D; Li H L; Asa S; Melmed S
Dominant negative inhibition of tumorigenesis in vivo by human insulin-like growth factor I receptor mutant.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(6):2181-5.
1994: Melmed S
Pituitary neoplasia.
Endocrinology and metabolism clinics of North America 1994;23(1):81-92.
1994: Greenman Y; Melmed S
Heterogeneous expression of two somatostatin receptor subtypes in pituitary tumors.
The Journal of clinical endocrinology and metabolism 1994;78(2):398-403.
1993: Yamamoto H; Prager D; Yamasaki H; Melmed S
Rat pituitary GC cell insulin-like growth factor-I receptor regulation.
Endocrinology 1993;133(3):1420-5.
1993: Prager D; Melmed S
Somatotroph insulin-like growth factor-I signaling.
Annals of the New York Academy of Sciences 1993;692():102-12.
1993: Melmed S
Medical management of acromegaly--what and when?
Acta endocrinologica 1993;129 Suppl 1():13-7.
1993: Herman V; Drazin N Z; Gonsky R; Melmed S
Molecular screening of pituitary adenomas for gene mutations and rearrangements.
The Journal of clinical endocrinology and metabolism 1993;77(1):50-5.
1993: Ezzat S; Melmed S; Endres D; Eyre D R; Singer F R
Biochemical assessment of bone formation and resorption in acromegaly.
The Journal of clinical endocrinology and metabolism 1993;76(6):1452-7.
1993: Yamasaki H; Prager D; Melmed S
Structure-function of the human insulin-like growth factor-I receptor: a discordance of somatotroph internalization and signaling.
Molecular endocrinology (Baltimore, Md.) 1993;7(5):681-5.
1993: Prager D; Weber M M; Gebremedhin S; Melmed S
Interaction between insulin and thyroid hormone in rat pituitary tumour cells: insulin attenuates tri-iodothyronine-induced growth hormone mRNA levels.
The Journal of endocrinology 1993;137(1):107-14.
1993: Ezzat S; Ezrin C; Yamashita S; Melmed S
Recurrent acromegaly resulting from ectopic growth hormone gene expression by a metastatic pancreatic tumor.
Cancer 1993;71(1):66-70.
1992: Ezzat S; Ren S G; Braunstein G D; Melmed S
Octreotide stimulates insulin-like growth factor-binding protein-1: a potential pituitary-independent mechanism for drug action.
The Journal of clinical endocrinology and metabolism 1992;75(6):1459-63.
1992: Prager D; Yamasaki H; Weber M M; Gebremedhin S; Melmed S
Human insulin-like growth factor I receptor function in pituitary cells is suppressed by a dominant negative mutant.
The Journal of clinical investigation 1992;90(5):2117-22.
1992: Weber M M; Melmed S; Rosenbloom J; Yamasaki H; Prager D
Rat somatotroph insulin-like growth factor-II (IGF-II) signaling: role of the IGF-I receptor.
Endocrinology 1992;131(5):2147-53.
1992: Ren S G; Ezzat S; Melmed S; Braunstein G D
Somatostatin analog induces insulin-like growth factor binding protein-1 (IGFBP-1) expression in human hepatoma cells.
Endocrinology 1992;131(5):2479-81.
1992: Yamasaki H; Prager D; Gebremedhin S; Melmed S
Human insulin-like growth factor I receptor 950tyrosine is required for somatotroph growth factor signal transduction.
The Journal of biological chemistry 1992;267(29):20953-8.
1992: Melmed S
Etiology of pituitary acromegaly.
Endocrinology and metabolism clinics of North America 1992;21(3):539-51.
1992: Ezzat S; Melmed S
Endocrine applications of the somatostatin analogue octreotide (Sandostatin).
Metabolism: clinical and experimental 1992;41(9 Suppl 2):34-8.
1991: Gonsky R; Herman V; Melmed S; Fagin J
Transforming DNA sequences present in human prolactin-secreting pituitary tumors.
Molecular endocrinology (Baltimore, Md.) 1991;5(11):1687-95.
1991: Melmed S
Extrapituitary acromegaly.
Endocrinology and metabolism clinics of North America 1991;20(3):507-18.
1991: Ezzat S; Ren S G; Braunstein G D; Melmed S
Octreotide stimulates insulin-like growth factor binding protein-1 (IGFBP-1) levels in acromegaly.
The Journal of clinical endocrinology and metabolism 1991;73(2):441-3.
1991: Ezzat S; Melmed S
Acromegaly: etiology, diagnosis and management.
Comprehensive therapy 1991;17(7):31-5.
1991: Yamasaki H; Prager D; Gebremedhin S; Melmed S
Insulin-like growth factor-I (IGF-I) attenuation of growth hormone is enhanced by overexpression of pituitary IGF-I receptors.
Molecular endocrinology (Baltimore, Md.) 1991;5(7):890-6.
1991: Ezzat S; Melmed S
Clinical review 18: Are patients with acromegaly at increased risk for neoplasia?
The Journal of clinical endocrinology and metabolism 1991;72(2):245-9.
1991: Ezzat S; Laks D; Oster J; Melmed S
Growth hormone regulation in primary fetal and neonatal rat pituitary cell cultures: the role of thyroid hormone.
Endocrinology 1991;128(2):937-43.
1991: Yamasaki H; Prager D; Gebremedhin S; Moise L; Melmed S
Binding and action of insulin-like growth factor I in pituitary tumor cells.
Endocrinology 1991;128(2):857-62.
1990: Herman V; Fagin J; Gonsky R; Kovacs K; Melmed S
Clonal origin of pituitary adenomas.
The Journal of clinical endocrinology and metabolism 1990;71(6):1427-33.
1990: Prager D; Gebremedhin S; Melmed S
An insulin-induced DNA-binding protein for the human growth hormone gene.
The Journal of clinical investigation 1990;85(5):1680-5.
1990: Melmed S
Acromegaly.
The New England journal of medicine 1990;322(14):966-77.
1989: Fagin J A; Fernandez-Mejia C; Melmed S
Pituitary insulin-like growth factor-I gene expression: regulation by triiodothyronine and growth hormone.
Endocrinology 1989;125(5):2385-91.
1989: Barakat S; Melmed S
Reversible shrinkage of a growth hormone-secreting pituitary adenoma by a long-acting somatostatin analogue, octreotide.
Archives of internal medicine 1989;149(6):1443-5.
1989: Morita S; Fernandez-Mejia C; Melmed S
Retinoic acid selectively stimulates growth hormone secretion and messenger ribonucleic acid levels in rat pituitary cells.
Endocrinology 1989;124(5):2052-6.
1989: Namba H; Morita S; Melmed S
Insulin-like growth factor-I action on growth hormone secretion and messenger ribonucleic acid levels: interaction with somatostatin.
Endocrinology 1989;124(4):1794-9.
1988: Prager D; Melmed S
Insulin regulates expression of the human growth hormone gene in transfected cells.
The Journal of biological chemistry 1988;263(32):16580-5.
1988: Melmed S; Ziel F H; Braunstein G D; Downs T; Frohman L A
Medical management of acromegaly due to ectopic production of growth hormone-releasing hormone by a carcinoid tumor.
The Journal of clinical endocrinology and metabolism 1988;67(2):395-9.
1988: Prager D; Yamashita S; Melmed S
Insulin regulates prolactin secretion and messenger ribonucleic acid levels in pituitary cells.
Endocrinology 1988;122(6):2946-52.
1987: Morita S; Yamashita S; Melmed S
Insulin-like growth factor I action on rat anterior pituitary cells: effects of intracellular messengers on growth hormone secretion and messenger ribonucleic acid levels.
Endocrinology 1987;121(6):2000-6.
1987: Yamashita S; Ong J; Melmed S
Regulation of human growth hormone gene expression by insulin-like growth factor I in transfected cells.
The Journal of biological chemistry 1987;262(27):13254-7.
1987: Melmed S; Rushakoff R J
Ectopic pituitary and hypothalamic hormone syndromes.
Endocrinology and metabolism clinics of North America 1987;16(3):805-21.

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