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Thomas Bayer

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Sathish Kumar; Sandra Theil; Thomas A Bayer; Janina Gerth; Oliver Wirths; Jochen Walter
Early intraneuronal accumulation and increased aggregation of phosphorylated Abeta in a mouse model of Alzheimer's disease.
Oliver Wirths; Wolfgang Härtig; Antje Hillmann; Laurent Pradier; Thomas A Bayer
Oligomeric Pyroglutamate Amyloid-β is Present in Microglia and a Subfraction of Vessels in Patients with Alzheimer's Disease: Implications for Immunotherapy.
Oliver Wirths; Thomas A Bayer
Intraneuronal Aβ accumulation and neurodegeneration: lessons from transgenic models.

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2013: Sathish Kumar; Sandra Theil; Thomas A Bayer; Janina Gerth; Oliver Wirths; Jochen Walter
Early intraneuronal accumulation and increased aggregation of phosphorylated Abeta in a mouse model of Alzheimer's disease.
Acta neuropathologica 2013;125(5):699-709.
2013: Oliver Wirths; Wolfgang Härtig; Antje Hillmann; Laurent Pradier; Thomas A Bayer
Oligomeric Pyroglutamate Amyloid-β is Present in Microglia and a Subfraction of Vessels in Patients with Alzheimer's Disease: Implications for Immunotherapy.
Journal of Alzheimer's disease : JAD 2013;35(4):741-9.
2012: Oliver Wirths; Thomas A Bayer
Intraneuronal Aβ accumulation and neurodegeneration: lessons from transgenic models.
Life sciences 2012;91(23-24):1148-52.
2012: Vivek Venkataramani; Oliver Wirths; Gerald G Wulf; Paul Thelen; Knut Thiele; Thomas A Bayer; Carl Ludwig Behnes; Lennart Opitz; Gabriella Salinas-Riester; Stefan Schweyer
Amyloid precursor protein is a biomarker for transformed human pluripotent stem cells.
The American journal of pathology 2012;180(4):1636-52.
2012: Antje Hillmann; Torsten Hoffmann; Stephan Schilling; Thomas Schneider-Axmann; Sascha Weggen; Thomas A Bayer; Bruno Bulic; Hans-Ulrich Demuth; Stefanie Hahn; Oliver Wirths
No improvement after chronic ibuprofen treatment in the 5XFAD mouse model of Alzheimer's disease.
Neurobiology of aging 2012;33(4):833.e39-50.
2012: Jessica L Wittnam; Henrik Zetterberg; Kaj Blennow; Hans-Ulrich Demuth; Mikael K Gustavsson; Birgit Koch; Erik Portelius; Stephan Schilling; Oliver Wirths; Thomas A Bayer
Pyroglutamate amyloid β (Aβ) aggravates behavioral deficits in transgenic amyloid mouse model for Alzheimer disease.
The Journal of biological chemistry 2012;287(11):8154-62.
2012: Vivek Venkataramani; Oliver Wirths; Herbert Budka; Wolfgang Härtig; Gabor Geza Kovacs; Thomas A Bayer
Antibody 9D5 recognizes oligomeric pyroglutamate amyloid-β in a fraction of amyloid-β deposits in Alzheimer's disease without cross-reactivity with other protein aggregates.
Journal of Alzheimer's disease : JAD 2012;29(2):361-71.
2012: Oliver Wirths; Annika Dins; Thomas A Bayer
AβPP accumulation and/or intraneuronal amyloid-β accumulation? The 3xTg-AD mouse model revisited.
Journal of Alzheimer's disease : JAD 2012;28(4):897-904.
2012: Sadim Jawhar; Carolin Jenneckens; Anna Trawicka; Thomas A Bayer; Oliver Wirths
Motor deficits, neuron loss, and reduced anxiety coinciding with axonal degeneration and intraneuronal Aβ aggregation in the 5XFAD mouse model of Alzheimer's disease.
Neurobiology of aging 2012;33(1):196.e29-40.
2012: Marie-Caroline Cotel; Sadim Jawhar; Thomas A Bayer; Ditte Z Christensen; Oliver Wirths
Environmental enrichment fails to rescue working memory deficits, neuron loss, and neurogenesis in APP/PS1KI mice.
Neurobiology of aging 2012;33(1):96-107.
2011: Sadim Jawhar; Oliver Wirths; Thomas A Bayer
Pyroglutamate amyloid-β (Aβ): a hatchet man in Alzheimer disease.
The Journal of biological chemistry 2011;286(45):38825-32.
2011: Daniela Kaden; Thomas A Bayer; Ashley I Bush; Ruth Danzeisen; Gerd Multhaup
Disturbed copper bioavailability in Alzheimer's disease.
International journal of Alzheimer's disease 2011;2011():345614.
2010: Ditte Z Christensen; Thomas A Bayer; Oliver Wirths
Intracellular Aß triggers neuron loss in the cholinergic system of the APP/PS1KI mouse model of Alzheimer's disease.
Neurobiology of aging 2010;31(7):1153-63.
2010: Ditte Z Christensen; Thomas Schneider-Axmann; Paul J Lucassen; Thomas A Bayer; Oliver Wirths
Accumulation of intraneuronal Abeta correlates with ApoE4 genotype.
Acta neuropathologica 2010;119(5):555-66.
2010: Oliver Wirths; Henning Breyhan; Andrea Marcello; Marie-Caroline Cotel; Wolfgang Brück; Thomas A Bayer
Inflammatory changes are tightly associated with neurodegeneration in the brain and spinal cord of the APP/PS1KI mouse model of Alzheimer's disease.
Neurobiology of aging 2010;31(5):747-57.
2010: Oliver Wirths; Thomas A Bayer
Neuron loss in transgenic mouse models of Alzheimer's disease.
International journal of Alzheimer's disease 2010;2010():.
2010: Thomas A Bayer; Oliver Wirths
Intracellular accumulation of amyloid-Beta - a predictor for synaptic dysfunction and neuron loss in Alzheimer's disease.
Frontiers in aging neuroscience 2010;2():8.
2010: Oliver Wirths; Tobias Bethge; Andrea Marcello; Anja Harmeier; Sadim Jawhar; Paul J Lucassen; Gerd Multhaup; David L Brody; Thomas Esparza; Martin Ingelsson; Hannu Kalimo; Lars Lannfelt; Thomas A Bayer
Pyroglutamate Abeta pathology in APP/PS1KI mice, sporadic and familial Alzheimer's disease cases.
Journal of neural transmission (Vienna, Austria : 1996) 2010;117(1):85-96.
2009: Ditte Z Christensen; Thomas A Bayer; Oliver Wirths
Formic acid is essential for immunohistochemical detection of aggregated intraneuronal Abeta peptides in mouse models of Alzheimer's disease.
Brain research 2009;1301():116-25.
2009: Oliver Wirths; Henning Breyhan; Holger Cynis; Stephan Schilling; Hans-Ulrich Demuth; Thomas A Bayer
Intraneuronal pyroglutamate-Abeta 3-42 triggers neurodegeneration and lethal neurological deficits in a transgenic mouse model.
Acta neuropathologica 2009;118(4):487-96.
2009: Henning Breyhan; Oliver Wirths; Kailai Duan; Andrea Marcello; Jens Rettig; Thomas A Bayer
APP/PS1KI bigenic mice develop early synaptic deficits and hippocampus atrophy.
Acta neuropathologica 2009;117(6):677-85.
2009: Carina Treiber; Mohiuddin Abdul Quadir; Philipp Voigt; Michal Radowski; Shangjie Xu; Lisa-Marie Munter; Thomas A Bayer; Michael Schaefer; Rainer Haag; Gerd Multhaup
Cellular copper import by nanocarrier systems, intracellular availability, and effects on amyloid beta peptide secretion.
Biochemistry 2009;48(20):4273-84.
2008: Ditte Zerlang Christensen; Sophie Luise Kraus; Antonius Flohr; Marie-Caroline Cotel; Oliver Wirths; Thomas A Bayer
Transient intraneuronal A beta rather than extracellular plaque pathology correlates with neuron loss in the frontal cortex of APP/PS1KI mice.
Acta neuropathologica 2008;116(6):647-55.
2008: Holger Kessler; Frank-Gerald Pajonk; Daniela Bach; Thomas Schneider-Axmann; Peter Falkai; Wolfgang Herrmann; Gerd Multhaup; Jens Wiltfang; Stephanie Schäfer; Oliver Wirths; Thomas A Bayer
Effect of copper intake on CSF parameters in patients with mild Alzheimer's disease: a pilot phase 2 clinical trial.
Journal of neural transmission (Vienna, Austria : 1996) 2008;115(12):1651-9.
2008: Holger Kessler; Thomas A Bayer; Daniela Bach; Thomas Schneider-Axmann; Tillmann Supprian; Wolfgang Herrmann; Manfred Haber; Gerd Multhaup; Peter Falkai; Frank-Gerald Pajonk
Intake of copper has no effect on cognition in patients with mild Alzheimer's disease: a pilot phase 2 clinical trial.
Journal of neural transmission (Vienna, Austria : 1996) 2008;115(8):1181-7.
2008: Marie-Caroline Cotel; Thomas A Bayer; Oliver Wirths
Age-dependent loss of dentate gyrus granule cells in APP/PS1KI mice.
Brain research 2008;1222():207-13.
2008: Oliver Wirths; Henning Breyhan; Stephanie Schäfer; Christian Roth; Thomas A Bayer
Deficits in working memory and motor performance in the APP/PS1ki mouse model for Alzheimer's disease.
Neurobiology of aging 2008;29(6):891-901.
2008: Thomas A Bayer; Oliver Wirths
Review on the APP/PS1KI mouse model: intraneuronal Abeta accumulation triggers axonopathy, neuron loss and working memory impairment.
Genes, brain, and behavior 2008;7 Suppl 1():6-11.
2008: Oliver Wirths; Thomas A Bayer
Motor impairment in Alzheimer's disease and transgenic Alzheimer's disease mouse models.
Genes, brain, and behavior 2008;7 Suppl 1():1-5.
2008: Thomas A Bayer; Henning Breyhan; Kailai Duan; Jens Rettig; Oliver Wirths
Intraneuronal beta-amyloid is a major risk factor--novel evidence from the APP/PS1KI mouse model.
Neuro-degenerative diseases 2008;5(3-4):140-2.
2007: Oliver Wirths; Joachim Weis; Rakez Kayed; Takaomi C Saido; Thomas A Bayer
Age-dependent axonal degeneration in an Alzheimer mouse model.
Neurobiology of aging 2007;28(11):1689-99.
2007: Oliver Wirths; Karin M Thelen; Dieter Lütjohann; Peter Falkai; Thomas A Bayer
Altered cholesterol metabolism in APP695-transfected neuroblastoma cells.
Brain research 2007;1152():209-14.
2007: Stephanie Schäfer; Frank-Gerald Pajonk; Gerd Multhaup; Thomas A Bayer
Copper and clioquinol treatment in young APP transgenic and wild-type mice: effects on life expectancy, body weight, and metal-ion levels.
Journal of molecular medicine (Berlin, Germany) 2007;85(4):405-13.
2007: Stephanie Schäfer; Oliver Wirths; Gerd Multhaup; Thomas A Bayer
Gender dependent APP processing in a transgenic mouse model of Alzheimer's disease.
Journal of neural transmission (Vienna, Austria : 1996) 2007;114(3):387-94.
2006: H Kessler; Frank-Gerald Pajonk; P Meisser; Thomas Schneider-Axmann; K-H Hoffmann; Tillmann Supprian; W Herrmann; R Obeid; Gerd Multhaup; Peter Falkai; Thomas A Bayer
Cerebrospinal fluid diagnostic markers correlate with lower plasma copper and ceruloplasmin in patients with Alzheimer's disease.
Journal of neural transmission (Vienna, Austria : 1996) 2006;113(11):1763-9.
2006: Karin M Thelen; Peter Falkai; Thomas A Bayer; Dieter Lütjohann
Cholesterol synthesis rate in human hippocampus declines with aging.
Neuroscience letters 2006;403(1-2):15-9.
2006: Thomas A Bayer; S Schäfer; H Breyhan; Oliver Wirths; Carina Treiber; Gerd Multhaup
A vicious circle: role of oxidative stress, intraneuronal Abeta and Cu in Alzheimer's disease.
Clinical neuropathology 2006;25(4):163-71.
2006: Oliver Wirths; Joachim Weis; Jacek Szczygielski; Gerd Multhaup; Thomas A Bayer
Axonopathy in an APP/PS1 transgenic mouse model of Alzheimer's disease.
Acta neuropathologica 2006;111(4):312-9.
2006: Oliver Wirths; Karin M Thelen; Henning Breyhan; Berta Luzón-Toro; Karl-Heinz Hoffmann; Peter Falkai; Dieter Lütjohann; Thomas A Bayer
Decreased plasma cholesterol levels during aging in transgenic mouse models of Alzheimer's disease.
Experimental gerontology 2006;41(2):220-4.
2005: J Szczygielski; A Mautes; W I Steudel; Peter Falkai; Thomas A Bayer; Oliver Wirths
Traumatic brain injury: cause or risk of Alzheimer's disease? A review of experimental studies.
Journal of neural transmission (Vienna, Austria : 1996) 2005;112(11):1547-64.
2005: Frank-Gerald Pajonk; Holger Kessler; Tillmann Supprian; Pegah Hamzei; Daniela Bach; Janina Schweickhardt; Wolfgang Herrmann; Rima Obeid; Andreas Simons; Peter Falkai; Gerd Multhaup; Thomas A Bayer
Cognitive decline correlates with low plasma concentrations of copper in patients with mild to moderate Alzheimer's disease.
Journal of Alzheimer's disease : JAD 2005;8(1):23-7.
2005: Bart P F Rutten; Nicolien M Van der Kolk; Stephanie Schafer; Marc A M J van Zandvoort; Thomas A Bayer; Harry W M Steinbusch; Christoph Schmitz
Age-related loss of synaptophysin immunoreactive presynaptic boutons within the hippocampus of APP751SL, PS1M146L, and APP751SL/PS1M146L transgenic mice.
The American journal of pathology 2005;167(1):161-73.
2005: Katrin Schuessel; Stephanie Schäfer; Thomas A Bayer; Christian Czech; Laurent Pradier; Franz Müller-Spahn; Walter E Müller; Anne Eckert
Impaired Cu/Zn-SOD activity contributes to increased oxidative damage in APP transgenic mice.
Neurobiology of disease 2005;18(1):89-99.
2004: Carina Treiber; Andreas Simons; Markus Strauss; Mathias Hafner; Roberto Cappai; Thomas A Bayer; Gerd Multhaup
Clioquinol mediates copper uptake and counteracts copper efflux activities of the amyloid precursor protein of Alzheimer's disease.
The Journal of biological chemistry 2004;279(50):51958-64.
2004: Oliver Wirths; Gerd Multhaup; Thomas A Bayer
A modified beta-amyloid hypothesis: intraneuronal accumulation of the beta-amyloid peptide--the first step of a fatal cascade.
Journal of neurochemistry 2004;91(3):513-20.
2004: caty casas; Nicolas Sergeant; Jean-Michel Itier; Véronique Blanchard; Oliver Wirths; Nicolien van der Kolk; Valérie Vingtdeux; Evita van de Steeg; Gwenaëlle Ret; Thierry Canton; Hervé Drobecq; Allan Clark; Bruno Bonici; André Delacourte; Jesus Benavides; Christoph Schmitz; Günter Tremp; Thomas A Bayer; Patrick Benoit; Laurent Pradier
Massive CA1/2 neuronal loss with intraneuronal and N-terminal truncated Abeta42 accumulation in a novel Alzheimer transgenic model.
The American journal of pathology 2004;165(4):1289-300.
2004: Ariane Schmechel; Markus Strauss; Andrea Schlicksupp; Rüdiger Pipkorn; Christian Haass; Thomas A Bayer; Gerd Multhaup
Human BACE forms dimers and colocalizes with APP.
The Journal of biological chemistry 2004;279(38):39710-7.
2004: Christoph Schmitz; Bart P F Rutten; Andrea Pielen; Stephanie Schäfer; Oliver Wirths; Günter Tremp; Christian Czech; Véronique Blanchard; Gerd Multhaup; Payam Rezaie; Hubert Korr; Harry W M Steinbusch; Laurent Pradier; Thomas A Bayer
Hippocampal neuron loss exceeds amyloid plaque load in a transgenic mouse model of Alzheimer's disease.
The American journal of pathology 2004;164(4):1495-502.
2003: Thomas A Bayer; Stephanie Schäfer; Andreas Simons; André Kemmling; Thomas Kamer; Ralf Tepest; Anne Eckert; Katrin Schüssel; Oliver Eikenberg; Christine Sturchler-Pierrat; Dorothee Abramowski; Matthias Staufenbiel; Gerd Multhaup
Dietary Cu stabilizes brain superoxide dismutase 1 activity and reduces amyloid Abeta production in APP23 transgenic mice.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(24):14187-92.
2003: Véronique Blanchard; Saliha Moussaoui; Christian Czech; Nathalie Touchet; Bruno Bonici; Michel Planche; Thierry Canton; Iness Jedidi; Micheline Gohin; Oliver Wirths; Thomas A Bayer; Dominique Langui; Charles Duyckaerts; Günter Tremp; Laurent Pradier
Time sequence of maturation of dystrophic neurites associated with Abeta deposits in APP/PS1 transgenic mice.
Experimental neurology 2003;184(1):247-63.
2003: Ariane Schmechel; Hanswalter Zentgraf; Stefan Scheuermann; Guenter Fritz; Rüdiger Pipkorn; Jennifer Reed; Konrad Beyreuther; Thomas A Bayer; Gerd Multhaup
Alzheimer beta-amyloid homodimers facilitate A beta fibrillization and the generation of conformational antibodies.
The Journal of biological chemistry 2003;278(37):35317-24.
2003: Bart P F Rutten; Oliver Wirths; Wilma D J Van De Berg; Stefan F Lichtenthaler; Jochen Vehoff; Harry W M Steinbusch; Hubert Korr; Konrad Beyreuther; Gerd Multhaup; Thomas A Bayer; Christoph Schmitz
No alterations of hippocampal neuronal number and synaptic bouton number in a transgenic mouse model expressing the beta-cleaved C-terminal APP fragment.
Neurobiology of disease 2003;12(2):110-20.
2003: Oliver Wirths; Thomas A Bayer
Alpha-synuclein, Abeta and Alzheimer's disease.
Progress in neuro-psychopharmacology & biological psychiatry 2003;27(1):103-8.
2002: Andreas Simons; Thomas Ruppert; Carsten Schmidt; Andrea Schlicksupp; Rüdiger Pipkorn; Jennifer Reed; Colin L Masters; Anthony R White; Roberto Cappai; Konrad Beyreuther; Thomas A Bayer; Gerd Multhaup
Evidence for a copper-binding superfamily of the amyloid precursor protein.
Biochemistry 2002;41(30):9310-20.
2002: Oliver Wirths; Gerd Multhaup; Christian Czech; Nicole Feldmann; Véronique Blanchard; Günter Tremp; Konrad Beyreuther; Laurent Pradier; Thomas A Bayer
Intraneuronal APP/A beta trafficking and plaque formation in beta-amyloid precursor protein and presenilin-1 transgenic mice.
Brain pathology (Zurich, Switzerland) 2002;12(3):275-86.
2002: Dieter Lütjohann; Andreas Brzezinka; Esther Barth; Dorothee Abramowski; Matthias Staufenbiel; Klaus Von Bergmann; Konrad Beyreuther; Gerd Multhaup; Thomas A Bayer
Profile of cholesterol-related sterols in aged amyloid precursor protein transgenic mouse brain.
Journal of lipid research 2002;43(7):1078-85.
2002: Gerd Multhaup; Stefan Scheuermann; Andrea Schlicksupp; Andreas Simons; Markus Strauss; André Kemmling; Christian Oehler; Roberto Cappai; Rüdiger Pipkorn; Thomas A Bayer
Possible mechanisms of APP-mediated oxidative stress in Alzheimer's disease.
Free radical biology & medicine 2002;33(1):45-51.
2001: Oliver Wirths; Gerd Multhaup; Christian Czech; Véronique Blanchard; Günter Tremp; Laurent Pradier; Konrad Beyreuther; Thomas A Bayer
Reelin in plaques of beta-amyloid precursor protein and presenilin-1 double-transgenic mice.
Neuroscience letters 2001;316(3):145-8.
2001: Stefan Scheuermann; B Hambsch; L Hesse; J Stumm; C Schmidt; Dirk Beher; Thomas A Bayer; Konrad Beyreuther; Gerd Multhaup
Homodimerization of amyloid precursor protein and its implication in the amyloidogenic pathway of Alzheimer's disease.
The Journal of biological chemistry 2001;276(36):33923-9.
2001: Oliver Wirths; Gerd Multhaup; Christian Czech; Véronique Blanchard; Saliha Moussaoui; Günter Tremp; Laurent Pradier; Konrad Beyreuther; Thomas A Bayer
Intraneuronal Abeta accumulation precedes plaque formation in beta-amyloid precursor protein and presenilin-1 double-transgenic mice.
Neuroscience letters 2001;306(1-2):116-20.
2001: Sascha Weggen; Ute Preuss; Torsten Pietsch; N Hilger; Ingrid Klawitz; Karl-Heinz Scheidtmann; Otmar D Wiestler; Thomas A Bayer
Identification of amplified genes from SV40 large T antigen-induced rat PNET cell lines by subtractive cDNA analysis and radiation hybrid mapping.
Oncogene 2001;20(16):2023-31.
2001: Thomas A Bayer; Oliver Wirths; K Majtényi; Tobias Hartmann; Gerd Multhaup; Konrad Beyreuther; Christian Czech
Key factors in Alzheimer's disease: beta-amyloid precursor protein processing, metabolism and intraneuronal transport.
Brain pathology (Zurich, Switzerland) 2001;11(1):1-11.
2000: Oliver Wirths; S Weickert; K Majtenyi; L Havas; Philipp J Kahle; Masayasu Okochi; Christian Haass; Gerd Multhaup; Konrad Beyreuther; Thomas A Bayer
Lewy body variant of Alzheimer's disease: alpha-synuclein in dystrophic neurites of A beta plaques.
Neuroreport 2000;11(17):3737-41.
2000: Wolfgang Block; Thomas A Bayer; Ralf Tepest; Frank Träber; Marcella Rietschel; Daniel J Müller; Thomas G. Schulze; William Honer; Wolfgang Maier; Hans H Schild; Peter Falkai
Decreased frontal lobe ratio of N-acetyl aspartate to choline in familial schizophrenia: a proton magnetic resonance spectroscopy study.
Neuroscience letters 2000;289(2):147-51.
2000: Thomas A Bayer; M Schramm; Nicole Feldmann; M B Knable; Peter Falkai
Antidepressant drug exposure is associated with mRNA levels of tyrosine receptor kinase B in major depressive disorder.
Progress in neuro-psychopharmacology & biological psychiatry 2000;24(6):881-8.
2000: K Ishii; F Muelhauser; U Liebl; M Picard; Sandra Kühl; Botond Penke; Thomas A Bayer; M Wiessler; Michael Hennerici; Konrad Beyreuther; Tobias Hartmann; Klaus Fassbender
Subacute NO generation induced by Alzheimer's beta-amyloid in the living brain: reversal by inhibition of the inducible NO synthase.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2000;14(11):1485-9.
2000: Sascha Weggen; Thomas A Bayer; Andreas von Deimling; Guido Reifenberger; Dietrich von Schweinitz; Otmar D Wiestler; Torsten Pietsch
Low frequency of SV40, JC and BK polyomavirus sequences in human medulloblastomas, meningiomas and ependymomas.
Brain pathology (Zurich, Switzerland) 2000;10(1):85-92.
2000: Kai Vogeley; Thomas Schneider-Axmann; Ute Pfeiffer; Ralf Tepest; Thomas A Bayer; B Bogerts; William Honer; Peter Falkai
Disturbed gyrification of the prefrontal region in male schizophrenic patients: A morphometric postmortem study.
The American journal of psychiatry 2000;157(1):34-9.
1999: Thomas A Bayer; P Jäkälä; Tobias Hartmann; R Egensperger; R Buslei; Peter Falkai; Konrad Beyreuther
Neural expression profile of alpha-synuclein in developing human cortex.
Neuroreport 1999;10(13):2799-803.
1999: Thomas A Bayer; R Buslei; L Havas; Peter Falkai
Evidence for activation of microglia in patients with psychiatric illnesses.
Neuroscience letters 1999;271(2):126-8.
1999: Thomas A Bayer; M Thier; Elke Roeb; B Breuer; Sascha Weggen; Otmar D Wiestler; J Weis
Migratory potential of transplantable neural tumor cell lines.
Acta neuropathologica 1999;97(6):607-12.
1999: A Diehlmann; N Ida; Sascha Weggen; J Grünberg; Christian Haass; Colin L Masters; Thomas A Bayer; Konrad Beyreuther
Analysis of presenilin 1 and presenilin 2 expression and processing by newly developed monoclonal antibodies.
Journal of neuroscience research 1999;56(4):405-19.
1999: Thomas A Bayer; P Jäkälä; Tobias Hartmann; L Havas; C McLean; Janetta G Culvenor; Qiao-Xin Li; Colin L Masters; Peter Falkai; Konrad Beyreuther
Alpha-synuclein accumulates in Lewy bodies in Parkinson's disease and dementia with Lewy bodies but not in Alzheimer's disease beta-amyloid plaque cores.
Neuroscience letters 1999;266(3):213-6.
1999: H Salewski; Thomas A Bayer; U Eidhoff; Ute Preuss; Sascha Weggen; Karl-Heinz Scheidtmann
Increased oncogenicity of subclones of SV40 large T-induced neuroectodermal tumor cell lines after loss of large T expression and concomitant mutation in p53.
Cancer research 1999;59(8):1980-6.
1999: P Falkai; William Honer; S David; B Bogerts; C Majtenyi; Thomas A Bayer
No evidence for astrogliosis in brains of schizophrenic patients. A post-mortem study.
Neuropathology and applied neurobiology 1999;25(1):48-53.
1999: R Egensperger; Sascha Weggen; N Ida; Gerd Multhaup; R Schnabel; Konrad Beyreuther; Thomas A Bayer
Reverse relationship between beta-amyloid precursor protein and beta-amyloid peptide plaques in Down's syndrome versus sporadic/familial Alzheimer's disease.
Acta neuropathologica 1999;97(2):113-8.
1999: M Schramm; Peter Falkai; Ralf Tepest; Thomas Schneider-Axmann; R Przkora; Andreas Waha; Torsten Pietsch; Wolfgang Bonte; Thomas A Bayer
Stability of RNA transcripts in post-mortem psychiatric brains.
Journal of neural transmission (Vienna, Austria : 1996) 1999;106(3-4):329-35.
1999: M Schramm; Peter Falkai; Torsten Pietsch; Iris Neidt; R Egensperger; Thomas A Bayer
Neural expression profile of Elav-like genes in human brain.
Clinical neuropathology 1999;18(1):17-22.
1998: M Schramm; Peter Falkai; Nicole Feldmann; M B Knable; Thomas A Bayer
Reduced tyrosine kinase receptor C mRNA levels in the frontal cortex of patients with schizophrenia.
Neuroscience letters 1998;257(2):65-8.
1998: Sascha Weggen; A Diehlmann; R Buslei; Konrad Beyreuther; Thomas A Bayer
Prominent expression of presenilin-1 in senile plaques and reactive astrocytes in Alzheimer's disease brain.
Neuroreport 1998;9(14):3279-83.
1998: R Przkora; Peter Falkai; Andreas von Deimling; Otmar D Wiestler; Margot Albus; Marcella Rietschel; Wolfgang Maier; Thomas A Bayer
Analysis of a polymorphism in the tuberous sclerosis (TSC2) gene does not predispose to schizophrenia.
European archives of psychiatry and clinical neuroscience 1998;248(6):314-5.
1997: Thomas A Bayer; Krzysztof Paliga; Sascha Weggen; Otmar D Wiestler; Konrad Beyreuther; Gerd Multhaup
Amyloid precursor-like protein 1 accumulates in neuritic plaques in Alzheimer's disease.
Acta neuropathologica 1997;94(6):519-24.
1997: Sascha Weggen; Thomas A Bayer; Arend Koch; H Salewski; Karl-Heinz Scheidtmann; Torsten Pietsch; Otmar D Wiestler
Characterization of neural cell lines derived from SV40 large T-induced primitive neuroectodermal tumors.
Brain pathology (Zurich, Switzerland) 1997;7(2):731-9.
1996: Thomas A Bayer; A Fossgreen; C Czech; Konrad Beyreuther; Otmar D Wiestler
Plaque formation in brain transplants exposed to human beta-amyloid precursor protein 695.
Acta neuropathologica 1996;92(2):130-7.
1995: Steffen Albrecht; Thomas A Bayer; J A Kraus; Torsten Pietsch
Transthyretin expression in medulloblastomas and medulloblastoma cell lines.
Neuropathology and applied neurobiology 1995;21(5):399-409.
1995: Thomas A Bayer; Otmar D Wiestler; HK Wolf
Hippocampal loss of N-methyl-D-aspartate receptor subunit 1 mRNA in chronic temporal lobe epilepsy.
Acta neuropathologica 1995;89(5):446-50.