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Douglas Melton
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7
Hemmati-Brivanlou, Ali
6
Hebrok, Matthias
6
Dor, Yuval
5
Stanger, Ben
5
Whitman, Malcolm
5
Murtaugh, Lewis C.
4
Maehr, Rene
4
Klein, Peter
3
Lammert, Eckhard
3
McMahon, Andrew
3
Sherwood, Richard
3
Wells, James
3
Cowan, Chad
3
Chen, Shuibing
3
Graff, Jonathan
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All Publications
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2009: Maehr René; Chen Shuibing; Snitow Melinda; Ludwig Thomas; Yagasaki Lisa; Goland Robin; Leibel Rudolph L; Melton Douglas A
Generation of pluripotent stem cells from patients with type 1 diabetes.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(37):15768-73.
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2009: Guseh J Sawalla; Bores Sam A; Stanger Ben Z; Zhou Qiao; Anderson William J; Melton Douglas A; Rajagopal Jayaraj
Notch signaling promotes airway mucous metaplasia and inhibits alveolar development.
Development (Cambridge, England) 2009;136(10):1751-9.
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2009: Borowiak Malgorzata; Maehr René; Chen Shuibing; Chen Alice E; Tang Weiping; Fox Julia L; Schreiber Stuart L; Melton Douglas A
Small molecules efficiently direct endodermal differentiation of mouse and human embryonic stem cells.
Cell stem cell 2009;4(4):348-58.
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2009: Chen Alice E; Egli Dieter; Niakan Kathy; Deng Jie; Akutsu Hidenori; Yamaki Mariko; Cowan Chad; Fitz-Gerald Claire; Zhang Kun; Melton Douglas A; Eggan Kevin
Optimal timing of inner cell mass isolation increases the efficiency of human embryonic stem cell derivation and allows generation of sibling cell lines.
Cell stem cell 2009;4(2):103-6.
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2009: Sherwood Richard I; Chen Tzong-Yang Albert; Melton Douglas A
Transcriptional dynamics of endodermal organ formation.
Developmental dynamics : an official publication of the American Association of Anatomists 2009;238(1):29-42.
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2008: Huangfu Danwei; Osafune Kenji; Maehr René; Guo Wenjun; Eijkelenboom Astrid; Chen Shuibing; Muhlestein Whitney; Melton Douglas A
Induction of pluripotent stem cells from primary human fibroblasts with only Oct4 and Sox2.
Nature biotechnology 2008;26(11):1269-75.
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2008: Zhou Qiao; Melton Douglas A
Extreme makeover: converting one cell into another.
Cell stem cell 2008;3(4):382-8.
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2008: Zhou Qiao; Brown Juliana; Kanarek Andrew; Rajagopal Jayaraj; Melton Douglas A
In vivo reprogramming of adult pancreatic exocrine cells to beta-cells.
Nature 2008;455(7213):627-32.
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2008: Huangfu Danwei; Maehr René; Guo Wenjun; Eijkelenboom Astrid; Snitow Melinda; Chen Alice E; Melton Douglas A
Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds.
Nature biotechnology 2008;26(7):795-7.
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2008: Rajagopal Jayaraj; Carroll Thomas J; Guseh J Sawalla; Bores Sam A; Blank Leah J; Anderson William J; Yu Jing; Zhou Qiao; McMahon Andrew P; Melton Douglas A
Wnt7b stimulates embryonic lung growth by coordinately increasing the replication of epithelium and mesenchyme.
Development (Cambridge, England) 2008;135(9):1625-34.
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2008: Anderson William J; Zhou Qiao; Alcalde Victor; Kaneko Osamu F; Blank Leah J; Sherwood Richard I; Guseh J Sawalla; Rajagopal Jayaraj; Melton Douglas A
Genetic targeting of the endoderm with claudin-6CreER.
Developmental dynamics : an official publication of the American Association of Anatomists 2008;237(2):504-12.
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2008: Dor Yuval; Melton Douglas A
Facultative endocrine progenitor cells in the adult pancreas.
Cell 2008;132(2):183-4.
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2008: Zhou Q; Melton D A
Pathways to new beta cells.
Cold Spring Harbor symposia on quantitative biology 2008;73():175-81.
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2007: Nir Tomer; Melton Douglas A; Dor Yuval
Recovery from diabetes in mice by beta cell regeneration.
The Journal of clinical investigation 2007;117(9):2553-61.
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2007: Zhou Qiao; Law Anica C; Rajagopal Jayaraj; Anderson William J; Gray Paul A; Melton Douglas A
A multipotent progenitor domain guides pancreatic organogenesis.
Developmental cell 2007;13(1):103-14.
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2007: Sherwood Richard I; Jitianu Cristian; Cleaver Ondine; Shaywitz David A; Lamenzo Julia O; Chen Alice E; Golub Todd R; Melton Douglas A
Prospective isolation and global gene expression analysis of definitive and visceral endoderm.
Developmental biology 2007;304(2):541-55.
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2007: Stanger Ben Z; Tanaka Akemi J; Melton Douglas A
Organ size is limited by the number of embryonic progenitor cells in the pancreas but not the liver.
Nature 2007;445(7130):886-91.
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2006: Lee Tong Ihn; Jenner Richard G; Boyer Laurie A; Guenther Matthew G; Levine Stuart S; Kumar Roshan M; Chevalier Brett; Johnstone Sarah E; Cole Megan F; Isono Kyo-ichi; Koseki Haruhiko; Fuchikami Takuya; Abe Kuniya; Murray Heather L; Zucker Jacob P; Yuan Bingbing; Bell George W; Herbolsheimer Elizabeth; Hannett Nancy M; Sun Kaiming; Odom Duncan T; Otte Arie P; Volkert Thomas L; Bartel David P; Melton Douglas A; Gifford David K; Jaenisch Rudolf; Young Richard A
Control of developmental regulators by Polycomb in human embryonic stem cells.
Cell 2006;125(2):301-13.
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2006: Nikolova Ganka; Jabs Normund; Konstantinova Irena; Domogatskaya Anna; Tryggvason Karl; Sorokin Lydia; Fässler Reinhard; Gu Guoqiang; Gerber Hans-Peter; Ferrara Napoleone; Melton Douglas A; Lammert Eckhard
The vascular basement membrane: a niche for insulin gene expression and Beta cell proliferation.
Developmental cell 2006;10(3):397-405.
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2005: Murtaugh L Charles; Law Anica C; Dor Yuval; Melton Douglas A
Beta-catenin is essential for pancreatic acinar but not islet development.
Development (Cambridge, England) 2005;132(21):4663-74.
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2005: Stanger Ben Z; Stiles Bangyan; Lauwers Gregory Y; Bardeesy Nabeel; Mendoza Michael; Wang Ying; Greenwood Amy; Cheng Kuang-hung; McLaughlin Margaret; Brown Dennis; Depinho Ronald A; Wu Hong; Melton Douglas A; Dor Yuval
Pten constrains centroacinar cell expansion and malignant transformation in the pancreas.
Cancer cell 2005;8(3):185-95.
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2005: Boyer Laurie A; Lee Tong Ihn; Cole Megan F; Johnstone Sarah E; Levine Stuart S; Zucker Jacob P; Guenther Matthew G; Kumar Roshan M; Murray Heather L; Jenner Richard G; Gifford David K; Melton Douglas A; Jaenisch Rudolf; Young Richard A
Core transcriptional regulatory circuitry in human embryonic stem cells.
Cell 2005;122(6):947-56.
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2005: Cowan Chad A; Atienza Jocelyn; Melton Douglas A; Eggan Kevin
Nuclear reprogramming of somatic cells after fusion with human embryonic stem cells.
Science (New York, N.Y.) 2005;309(5739):1369-73.
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2005: Stanger Ben Z; Datar Radhika; Murtaugh L Charles; Melton Douglas A
Direct regulation of intestinal fate by Notch.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(35):12443-8.
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2005: Shaywitz David A; Melton Douglas A
The molecular biography of the cell.
Cell 2005;120(6):729-31.
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2004: Dor Yuval; Melton Douglas A
How important are adult stem cells for tissue maintenance?
Cell cycle (Georgetown, Tex.) 2004;3(9):1104-6.
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2004: Annerén Cecilia; Cowan Chad A; Melton Douglas A
The Src family of tyrosine kinases is important for embryonic stem cell self-renewal.
The Journal of biological chemistry 2004;279(30):31590-8.
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2004: Dor Yuval; Brown Juliana; Martinez Olga I; Melton Douglas A
Adult pancreatic beta-cells are formed by self-duplication rather than stem-cell differentiation.
Nature 2004;429(6987):41-6.
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2004: Cowan Chad A; Klimanskaya Irina; McMahon Jill; Atienza Jocelyn; Witmyer Jeannine; Zucker Jacob P; Wang Shunping; Morton Cynthia C; McMahon Andrew P; Powers Doug; Melton Douglas A
Derivation of embryonic stem-cell lines from human blastocysts.
The New England journal of medicine 2004;350(13):1353-6.
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2004: Gu Guoqiang; Wells James M; Dombkowski David; Preffer Fred; Aronow Bruce; Melton Douglas A
Global expression analysis of gene regulatory pathways during endocrine pancreatic development.
Development (Cambridge, England) 2004;131(1):165-79.
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2003: Murtaugh L Charles; Stanger Ben Z; Kwan Kristen M; Melton Douglas A
Notch signaling controls multiple steps of pancreatic differentiation.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(25):14920-5.
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2003: Lammert Eckhard; Gu Guqiang; McLaughlin Margaret; Brown Dennis; Brekken Rolf; Murtaugh Lewis Charles; Gerber Hans Peter; Ferrara Napoleone; Melton Douglas A
Role of VEGF-A in vascularization of pancreatic islets.
Current biology : CB 2003;13(12):1070-4.
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2003: Cleaver Ondine; Melton Douglas A
Endothelial signaling during development.
Nature medicine 2003;9(6):661-8.
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2003: Chiang Ming-Ko; Melton Douglas A
Single-cell transcript analysis of pancreas development.
Developmental cell 2003;4(3):383-93.
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2003: Rajagopal Jayaraj; Anderson William J; Kume Shoen; Martinez Olga I; Melton Douglas A
Insulin staining of ES cell progeny from insulin uptake.
Science (New York, N.Y.) 2003;299(5605):363.
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2003: Murtaugh L Charles; Melton Douglas A
Genes, signals, and lineages in pancreas development.
Annual review of cell and developmental biology 2003;19():71-89.
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2002: Ramalho-Santos Miguel; Yoon Soonsang; Matsuzaki Yumi; Mulligan Richard C; Melton Douglas A
"Stemness": transcriptional profiling of embryonic and adult stem cells.
Science (New York, N.Y.) 2002;298(5593):597-600.
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2002: Gu Guoqiang; Dubauskaite Jolanta; Melton Douglas A
Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors.
Development (Cambridge, England) 2002;129(10):2447-57.
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2002: Fishman Martha P; Melton Douglas A
Pancreatic lineage analysis using a retroviral vector in embryonic mice demonstrates a common progenitor for endocrine and exocrine cells.
The International journal of developmental biology 2002;46(2):201-7.
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2001: Grapin-Botton A; Majithia A R; Melton D A
Key events of pancreas formation are triggered in gut endoderm by ectopic expression of pancreatic regulatory genes.
Genes & development 2001;15(4):444-54.
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2000: Hebrok M; Kim S K; St Jacques B; McMahon A P; Melton D A
Regulation of pancreas development by hedgehog signaling.
Development (Cambridge, England) 2000;127(22):4905-13.
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2000: Schuldiner M; Yanuka O; Itskovitz-Eldor J; Melton D A; Benvenisty N
Effects of eight growth factors on the differentiation of cells derived from human embryonic stem cells.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(21):11307-12.
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2000: Kim S K; Hebrok M; Li E; Oh S P; Schrewe H; Harmon E B; Lee J S; Melton D A
Activin receptor patterning of foregut organogenesis.
Genes & development 2000;14(15):1866-71.
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2000: Lammert E; Brown J; Melton D A
Notch gene expression during pancreatic organogenesis.
Mechanisms of development 2000;94(1-2):199-203.
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2000: Ramalho-Santos M; Melton D A; McMahon A P
Hedgehog signals regulate multiple aspects of gastrointestinal development.
Development (Cambridge, England) 2000;127(12):2763-72.
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2000: Wells J M; Melton D A
Early mouse endoderm is patterned by soluble factors from adjacent germ layers.
Development (Cambridge, England) 2000;127(8):1563-72.
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2000: Grapin-Botton A; Melton D A
Endoderm development: from patterning to organogenesis.
Trends in genetics : TIG 2000;16(3):124-30.
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1999: Hebrok M; Kim S K; Melton D A
Screening for novel pancreatic genes expressed during embryogenesis.
Diabetes 1999;48(8):1550-6.
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1999: Wells J M; Melton D A
Vertebrate endoderm development.
Annual review of cell and developmental biology 1999;15():393-410.
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1998: Kim S K; Melton D A
Pancreas development is promoted by cyclopamine, a hedgehog signaling inhibitor.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(22):13036-41.
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1998: Henry G L; Melton D A
Mixer, a homeobox gene required for endoderm development.
Science (New York, N.Y.) 1998;281(5373):91-6.
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1998: Joseph E M; Melton D A
Mutant Vg1 ligands disrupt endoderm and mesoderm formation in Xenopus embryos.
Development (Cambridge, England) 1998;125(14):2677-85.
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1998: Hebrok M; Kim S K; Melton D A
Notochord repression of endodermal Sonic hedgehog permits pancreas development.
Genes & development 1998;12(11):1705-13.
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1997: Kim S K; Hebrok M; Melton D A
Notochord to endoderm signaling is required for pancreas development.
Development (Cambridge, England) 1997;124(21):4243-52.
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1997: Joseph E M; Melton D A
Xnr4: a Xenopus nodal-related gene expressed in the Spemann organizer.
Developmental biology 1997;184(2):367-72.
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1997: Kim S K; Hebrok M; Melton D A
Pancreas development in the chick embryo.
Cold Spring Harbor symposia on quantitative biology 1997;62():377-83.
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1996: Reilly K M; Melton D A
Short-range signaling by candidate morphogens of the TGF beta family and evidence for a relay mechanism of induction.
Cell 1996;86(5):743-54.
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1996: Klein P S; Melton D A
A molecular mechanism for the effect of lithium on development.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(16):8455-9.
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1996: Newfeld S J; Chartoff E H; Graff J M; Melton D A; Gelbart W M
Mothers against dpp encodes a conserved cytoplasmic protein required in DPP/TGF-beta responsive cells.
Development (Cambridge, England) 1996;122(7):2099-108.
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1996: Graff J M; Bansal A; Melton D A
Xenopus Mad proteins transduce distinct subsets of signals for the TGF beta superfamily.
Cell 1996;85(4):479-87.
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1996: Dohrmann C E; Kessler D S; Melton D A
Induction of axial mesoderm by zDVR-1, the zebrafish orthologue of Xenopus Vg1.
Developmental biology 1996;175(1):108-17.
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1996: Henry G L; Brivanlou I H; Kessler D S; Hemmati-Brivanlou A; Melton D A
TGF-beta signals and a pattern in Xenopus laevis endodermal development.
Development (Cambridge, England) 1996;122(3):1007-15.
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1995: Kessler D S; Melton D A
Induction of dorsal mesoderm by soluble, mature Vg1 protein.
Development (Cambridge, England) 1995;121(7):2155-64.
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1995: Kelly O G; Melton D A
Induction and patterning of the vertebrate nervous system.
Trends in genetics : TIG 1995;11(7):273-8.
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1995: Klein P S; Melton D A
Translational control of activin in Xenopus laevis embryos.
Developmental genetics 1995;17(1):55-64.
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1994: Kessler D S; Melton D A
Vertebrate embryonic induction: mesodermal and neural patterning.
Science (New York, N.Y.) 1994;266(5185):596-604.
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1994: Graff J M; Thies R S; Song J J; Celeste A J; Melton D A
Studies with a Xenopus BMP receptor suggest that ventral mesoderm-inducing signals override dorsal signals in vivo.
Cell 1994;79(1):169-79.
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1994: Klein P S; Melton D A
Induction of mesoderm in Xenopus laevis embryos by translation initiation factor 4E.
Science (New York, N.Y.) 1994;265(5173):803-6.
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1994: Wilson P A; Melton D A
Mesodermal patterning by an inducer gradient depends on secondary cell-cell communication.
Current biology : CB 1994;4(8):676-86.
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1994: Klein P S; Melton D A
Hormonal regulation of embryogenesis: the formation of mesoderm in Xenopus laevis.
Endocrine reviews 1994;15(3):326-41.
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1994: Hemmati-Brivanlou A; Kelly O G; Melton D A
Follistatin, an antagonist of activin, is expressed in the Spemann organizer and displays direct neuralizing activity.
Cell 1994;77(2):283-95.
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1994: Hemmati-Brivanlou A; Melton D A
Inhibition of activin receptor signaling promotes neuralization in Xenopus.
Cell 1994;77(2):273-81.
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1993: Ku M; Melton D A
Xwnt-11: a maternally expressed Xenopus wnt gene.
Development (Cambridge, England) 1993;119(4):1161-73.
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1993: Thomsen G H; Melton D A
Processed Vg1 protein is an axial mesoderm inducer in Xenopus.
Cell 1993;74(3):433-41.
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1993: Dohrmann C E; Hemmati-Brivanlou A; Thomsen G H; Fields A; Woolf T M; Melton D A
Expression of activin mRNA during early development in Xenopus laevis.
Developmental biology 1993;157(2):474-83.
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1993: Steinbeisser H; De Robertis E M; Ku M; Kessler D S; Melton D A
Xenopus axis formation: induction of goosecoid by injected Xwnt-8 and activin mRNAs.
Development (Cambridge, England) 1993;118(2):499-507.
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1992: Sokol S Y; Melton D A
Interaction of Wnt and activin in dorsal mesoderm induction in Xenopus.
Developmental biology 1992;154(2):348-55.
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1992: Hemmati-Brivanlou A; Melton D A
A truncated activin receptor inhibits mesoderm induction and formation of axial structures in Xenopus embryos.
Nature 1992;359(6396):609-14.
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1992: Woolf T M; Melton D A; Jennings C G
Specificity of antisense oligonucleotides in vivo.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(16):7305-9.
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1992: Whitman M; Melton D A
Involvement of p21ras in Xenopus mesoderm induction.
Nature 1992;357(6375):252-4.
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1992: Hemmati-Brivanlou A; Wright D A; Melton D A
Embryonic expression and functional analysis of a Xenopus activin receptor.
Developmental dynamics : an official publication of the American Association of Anatomists 1992;194(1):1-11.
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1992: Mowry K L; Melton D A
Vegetal messenger RNA localization directed by a 340-nt RNA sequence element in Xenopus oocytes.
Science (New York, N.Y.) 1992;255(5047):991-4.
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1991: Sokol S; Christian J L; Moon R T; Melton D A
Injected Wnt RNA induces a complete body axis in Xenopus embryos.
Cell 1991;67(4):741-52.
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1991: Sokol S; Melton D A
Pre-existent pattern in Xenopus animal pole cells revealed by induction with activin.
Nature 1991;351(6325):409-11.
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1991: Melton D A
Pattern formation during animal development.
Science (New York, N.Y.) 1991;252(5003):234-41.
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1991: O'Keefe H P; Melton D A; Ferreiro B; Kintner C
In situ hyridization.
Methods in cell biology 1991;36():443-63.
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1991: Vize P D; Melton D A; Hemmati-Brivanlou A; Harland R M
Assays for gene function in developing Xenopus embryos.
Methods in cell biology 1991;36():367-87.
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1990: Thomsen G; Woolf T; Whitman M; Sokol S; Vaughan J; Vale W; Melton D A
Activins are expressed early in Xenopus embryogenesis and can induce axial mesoderm and anterior structures.
Cell 1990;63(3):485-93.
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1990: Sokol S; Wong G G; Melton D A
A mouse macrophage factor induces head structures and organizes a body axis in Xenopus.
Science (New York, N.Y.) 1990;249(4968):561-4.
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1990: Woolf T M; Jennings C G; Rebagliati M; Melton D A
The stability, toxicity and effectiveness of unmodified and phosphorothioate antisense oligodeoxynucleotides in Xenopus oocytes and embryos.
Nucleic acids research 1990;18(7):1763-9.
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1990: Yisraeli J K; Sokol S; Melton D A
A two-step model for the localization of maternal mRNA in Xenopus oocytes: involvement of microtubules and microfilaments in the translocation and anchoring of Vg1 mRNA.
Development (Cambridge, England) 1990;108(2):289-98.
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1990: Ruiz i Altaba A; Melton D A
Axial patterning and the establishment of polarity in the frog embryo.
Trends in genetics : TIG 1990;6(2):57-64.
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1990: Whitman M; Melton D A
Signal transduction during mesoderm induction in Xenopus.
Journal of reproduction and fertility. Supplement 1990;42():249-54.
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1989: Ruiz i Altaba A; Melton D A
Interaction between peptide growth factors and homoeobox genes in the establishment of antero-posterior polarity in frog embryos.
Nature 1989;341(6237):33-8.
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1989: Tannahill D; Melton D A
Localized synthesis of the Vg1 protein during early Xenopus development.
Development (Cambridge, England) 1989;106(4):775-85.
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1989: Krieg P A; Varnum S M; Wormington W M; Melton D A
The mRNA encoding elongation factor 1-alpha (EF-1 alpha) is a major transcript at the midblastula transition in Xenopus.
Developmental biology 1989;133(1):93-100.
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1989: Whitman M; Melton D A
Induction of mesoderm by a viral oncogene in early Xenopus embryos.
Science (New York, N.Y.) 1989;244(4906):803-6.
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1989: Ruiz i Altaba A; Melton D A
Bimodal and graded expression of the Xenopus homeobox gene Xhox3 during embryonic development.
Development (Cambridge, England) 1989;106(1):173-83.
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1989: Ruiz i Altaba A; Melton D A
Involvement of the Xenopus homeobox gene Xhox3 in pattern formation along the anterior-posterior axis.
Cell 1989;57(2):317-26.
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1989: Whitman M; Melton D A
Growth factors in early embryogenesis.
Annual review of cell biology 1989;5():93-117.
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1989: Melton D A; Ruiz i Altaba A; Yisraeli J; Sokol S
Localization of mRNA and axis formation during Xenopus embryogenesis.
Ciba Foundation symposium 1989;144():16-29; discussion 29-36, 92-8.
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1989: Yisraeli J K; Sokol S; Melton D A
The process of localizing a maternal messenger RNA in Xenopus oocytes.
Development (Cambridge, England) 1989;107 Suppl():31-6.
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1989: Yisraeli J K; Melton D A
Synthesis of long, capped transcripts in vitro by SP6 and T7 RNA polymerases.
Methods in enzymology 1989;180():42-50.
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1988: Yisraeli J K; Melton D A
The material mRNA Vg1 is correctly localized following injection into Xenopus oocytes.
Nature 1988;336(6199):592-5.
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1988: Harvey R P; Melton D A
Microinjection of synthetic Xhox-1A homeobox mRNA disrupts somite formation in developing Xenopus embryos.
Cell 1988;53(5):687-97.
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1987: Weeks D L; Melton D A
A maternal mRNA localized to the vegetal hemisphere in Xenopus eggs codes for a growth factor related to TGF-beta.
Cell 1987;51(5):861-7.
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1987: Ruiz i Altaba A; Perry-O'Keefe H; Melton D A
Xfin: an embryonic gene encoding a multifingered protein in Xenopus.
The EMBO journal 1987;6(10):3065-70.
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1987: Kintner C R; Melton D A
Expression of Xenopus N-CAM RNA in ectoderm is an early response to neural induction.
Development (Cambridge, England) 1987;99(3):311-25.
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1987: Rebagliati M R; Melton D A
Antisense RNA injections in fertilized frog eggs reveal an RNA duplex unwinding activity.
Cell 1987;48(4):599-605.
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1986: Melton D A; Rebagliati M R
Anti-sense RNA injections in fertilized eggs as a test for the function of localized mRNAs.
Journal of embryology and experimental morphology 1986;97 Suppl():211-21.
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1985: Rebagliati M R; Weeks D L; Harvey R P; Melton D A
Identification and cloning of localized maternal RNAs from Xenopus eggs.
Cell 1985;42(3):769-77.
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1985: Weeks D L; Rebagliati M R; Harvey R P; Melton D A
Localized maternal mRNAs in Xenopus laevis eggs.
Cold Spring Harbor symposia on quantitative biology 1985;50():21-30.
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1984: Melton D A; Krieg P A; Rebagliati M R; Maniatis T; Zinn K; Green M R
Efficient in vitro synthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter.
Nucleic acids research 1984;12(18):7035-56.
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