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Yves Mély

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Procedures

Fluorescence Spectrometry

Chemicals & Drugs

Living Beings

HIV-1

Concepts & Ideas

Genes & Molecular Sequences

Amino Acid Sequence

Anatomy

Phenomena

Protein Binding

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Co-Publications
Name
25
Roques, Bernard
24
Duportail, Guy
20
Klymchenko, Andrey
18
Darlix, Jean-Luc
17
de Rocquigny, Hugues
13
Piémont, Etienne
12
Morellet, Nelly
10
Gérard, Dominique
9
Ficheux, Damien
8
Bombarda, Elisa
8
Yushchenko, Dmytro
7
Schaub, Emmanuel
7
Shvadchak, Volodymyr
7
Vuilleumier, C
7
Clamme, Jean-Pierre

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Publications

TOP 3
Das Ranjan; Klymchenko Andrey S; Duportail Guy; Mély Yves
Unusually slow proton transfer dynamics of a 3-hydroxychromone dye in protic solvents.
Hayek Ali; Bolze Frédéric; Bourgogne Cyril; Baldeck Patrice L; Didier Pascal; Arntz Youri; Mély Yves; Nicoud Jean-François
Boron containing two-photon absorbing chromophores. 2. Fine tuning of the one- and two-photon photophysical properties of pyrazabole based fluorescent bioprobes.
Didier Pascal; Ulrich Gilles; Mély Yves; Ziessel Raymond
Improved push-pull-push E-Bodipy fluorophores for two-photon cell-imaging.

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All Publications

2009: Das Ranjan; Klymchenko Andrey S; Duportail Guy; Mély Yves
Unusually slow proton transfer dynamics of a 3-hydroxychromone dye in protic solvents.
Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 2009;8(11):1583-9.
2009: Hayek Ali; Bolze Frédéric; Bourgogne Cyril; Baldeck Patrice L; Didier Pascal; Arntz Youri; Mély Yves; Nicoud Jean-François
Boron containing two-photon absorbing chromophores. 2. Fine tuning of the one- and two-photon photophysical properties of pyrazabole based fluorescent bioprobes.
Inorganic chemistry 2009;48(19):9112-9.
2009: Didier Pascal; Ulrich Gilles; Mély Yves; Ziessel Raymond
Improved push-pull-push E-Bodipy fluorophores for two-photon cell-imaging.
Organic & biomolecular chemistry 2009;7(18):3639-42.
2009: Shvadchak Volodymyr; Sanglier Sarah; Rocle Sandrine; Villa Pascal; Haiech Jacques; Hibert Marcel; Van Dorsselaer Alain; Mély Yves; de Rocquigny Hugues
Identification by high throughput screening of small compounds inhibiting the nucleic acid destabilization activity of the HIV-1 nucleocapsid protein.
Biochimie 2009;91(7):916-23.
2009: Demchenko Alexander P; Mély Yves; Duportail Guy; Klymchenko Andrey S
Monitoring biophysical properties of lipid membranes by environment-sensitive fluorescent probes.
Biophysical journal 2009;96(9):3461-70.
2009: Bilokin' Mykhailo D; Shvadchak Volodymyr V; Yushchenko Dmytro A; Duportail Guy; Mély Yves; Pivovarenko Vasyl G
Dual-fluorescence probe of environment basicity (hydrogen bond accepting ability) displaying no sensitivity to polarity.
Journal of fluorescence 2009;19(3):545-53.
2009: Didier Pascal; Godet Julien; Mély Yves
Two-photon two-focus fluorescence correlation spectroscopy with a tunable distance between the excitation volumes.
Journal of fluorescence 2009;19(3):561-5.
2009: Shvadchak Volodymyr V; Klymchenko Andrey S; de Rocquigny Hugues; Mély Yves
Sensing peptide-oligonucleotide interactions by a two-color fluorescence label: application to the HIV-1 nucleocapsid protein.
Nucleic acids research 2009;37(3):e25.
2009: Klymchenko Andrey S; Oncul Sule; Didier Pascal; Schaub Emmanuel; Bagatolli Luis; Duportail Guy; Mély Yves
Visualization of lipid domains in giant unilamellar vesicles using an environment-sensitive membrane probe based on 3-hydroxyflavone.
Biochimica et biophysica acta 2009;1788(2):495-9.
2008: Grohmann Dina; Godet Julien; Mély Yves; Darlix Jean-Luc; Restle Tobias
HIV-1 nucleocapsid traps reverse transcriptase on nucleic acid substrates.
Biochemistry 2008;47(46):12230-40.
2008: Bourbigot Sarah; Ramalanjaona Nick; Boudier Christian; Salgado Gilmar F J; Roques Bernard P; Mély Yves; Bouaziz Serge; Morellet Nelly
How the HIV-1 nucleocapsid protein binds and destabilises the (-)primer binding site during reverse transcription.
Journal of molecular biology 2008;383(5):1112-28.
2008: Klymchenko Andrey S; Shvadchak Volodymyr V; Yushchenko Dmytro A; Jain Namrata; Mély Yves
Excited-state intramolecular proton transfer distinguishes microenvironments in single- and double-stranded DNA.
The journal of physical chemistry. B 2008;112(38):12050-5.
2008: Das Ranjan; Klymchenko Andrey S; Duportail Guy; Mély Yves
Excited state proton transfer and solvent relaxation of a 3-hydroxyflavone probe in lipid bilayers.
The journal of physical chemistry. B 2008;112(38):11929-35.
2008: Enander Karin; Choulier Laurence; Olsson A Linnéa; Yushchenko Dmytro A; Kanmert Daniel; Klymchenko Andrey S; Demchenko Alexander P; Mély Yves; Altschuh Danièle
A peptide-based, ratiometric biosensor construct for direct fluorescence detection of a protein analyte.
Bioconjugate chemistry 2008;19(9):1864-70.
2008: Kenfack Cyril A; Piémont Etienne; Ben Gaied Nouha; Burger Alain; Mély Yves
Time-resolved fluorescent properties of 8-vinyl-deoxyadenosine and 2-amino-deoxyribosylpurine exhibit different sensitivity to their opposite base in duplexes.
The journal of physical chemistry. B 2008;112(32):9736-45.
2008: Zhang Xin; Sharma Kamal Kant; Boeglin Marcel; Ogier Joelle; Mainard Didier; Voegel Jean-Claude; Mély Yves; Benkirane-Jessel Nadia
Transfection ability and intracellular DNA pathway of nanostructured gene-delivery systems.
Nano letters 2008;8(8):2432-6.
2008: M'Baye Gora; Mély Yves; Duportail Guy; Klymchenko Andrey S
Liquid ordered and gel phases of lipid bilayers: fluorescent probes reveal close fluidity but different hydration.
Biophysical journal 2008;95(3):1217-25.
2008: Kuciak Monika; Gabus Caroline; Ivanyi-Nagy Roland; Semrad Katharina; Storchak Roman; Chaloin Olivier; Muller Sylviane; Mély Yves; Darlix Jean-Luc
The HIV-1 transcriptional activator Tat has potent nucleic acid chaperoning activities in vitro.
Nucleic acids research 2008;36(10):3389-400.
2008: Brandner Katrin; Sambade Adrian; Boutant Emmanuel; Didier Pascal; Mély Yves; Ritzenthaler Christophe; Heinlein Manfred
Tobacco mosaic virus movement protein interacts with green fluorescent protein-tagged microtubule end-binding protein 1.
Plant physiology 2008;147(2):611-23.
2008: Zhang Xin; Ercelen Sebnem; Duportail Guy; Schaub Emmanuel; Tikhonov Vladimir; Slita Alexander; Zarubaev Vladimir; Babak Valery; Mély Yves
Hydrophobically modified low molecular weight chitosans as efficient and nontoxic gene delivery vectors.
The journal of gene medicine 2008;10(5):527-39.
2008: Dietz Julia; Koch Joachim; Kaur Ajit; Raja Chinnappan; Stein Stefan; Grez Manuel; Pustowka Anette; Mensch Sarah; Ferner Jan; Möller Lars; Bannert Norbert; Tampé Robert; Divita Gilles; Mély Yves; Schwalbe Harald; Dietrich Ursula
Inhibition of HIV-1 by a peptide ligand of the genomic RNA packaging signal Psi.
ChemMedChem 2008;3(5):749-55.
2008: Ouedraogo Moussa; Lecat Sandra; Rochdi Moulay Driss; Hachet-Haas Muriel; Matthes Hans; Gicquiaux Hervé; Verrier Sophie; Gaire Mireille; Glasser Nicole; Mély Yves; Takeda Kenneth; Bouvier Michel; Galzi Jean-Luc; Bucher Bernard
Distinct motifs of neuropeptide Y receptors differentially regulate trafficking and desensitization.
Traffic (Copenhagen, Denmark) 2008;9(3):305-24.
2008: Avilov S V; Piemont E; Shvadchak V; de Rocquigny H; Mély Y
Probing dynamics of HIV-1 nucleocapsid protein/target hexanucleotide complexes by 2-aminopurine.
Nucleic acids research 2008;36(3):885-96.
2008: de Rocquigny Hugues; Shvadchak Volodymyr; Avilov Sergiy; Dong Chang Zhi; Dietrich Ursula; Darlix Jean-Luc; Mély Yves
Targeting the viral nucleocapsid protein in anti-HIV-1 therapy.
Mini reviews in medicinal chemistry 2008;8(1):24-35.
2008: Fritz Joëlle V; Didier Pascal; Clamme Jean-Pierre; Schaub Emmanuel; Muriaux Delphine; Cabanne Charlotte; Morellet Nelly; Bouaziz Serge; Darlix Jean-Luc; Mély Yves; de Rocquigny Hugues
Direct Vpr-Vpr interaction in cells monitored by two photon fluorescence correlation spectroscopy and fluorescence lifetime imaging.
Retrovirology 2008;5():87.
2008: Egelé Caroline; Barbier Pascale; Didier Pascal; Piémont Etienne; Allegro Diane; Chaloin Olivier; Muller Sylviane; Peyrot Vincent; Mély Yves
Modulation of microtubule assembly by the HIV-1 Tat protein is strongly dependent on zinc binding to Tat.
Retrovirology 2008;5():62.
2008: Berkhout Ben; Gorelick Robert; Summers Michael F; Mély Yves; Darlix Jean-Luc
6th international symposium on retroviral nucleocapsid.
Retrovirology 2008;5():21.
2007: Ramalanjaona Nick; de Rocquigny Hugues; Millet Aurélie; Ficheux Damien; Darlix Jean-Luc; Mély Yves
Investigating the mechanism of the nucleocapsid protein chaperoning of the second strand transfer during HIV-1 DNA synthesis.
Journal of molecular biology 2007;374(4):1041-53.
2007: Egelé Caroline; Piémont Etienne; Didier Pascal; Ficheux Damien; Roques Bernard; Darlix Jean-Luc; de Rocquigny Hugues; Mély Yves
The single-finger nucleocapsid protein of moloney murine leukemia virus binds and destabilizes the TAR sequences of HIV-1 but does not promote efficiently their annealing.
Biochemistry 2007;46(50):14650-62.
2007: Yushchenko Dmytro A; Shvadchak Volodymyr V; Klymchenko Andrey S; Duportail Guy; Pivovarenko Vasyl G; Mély Yves
Modulation of excited-state intramolecular proton transfer by viscosity in protic media.
The journal of physical chemistry. A 2007;111(42):10435-8.
2007: Hayek Ali; Grichine Alexei; Huault Thomas; Ricard Clément; Bolze Frédéric; Van Der Sanden Boudewijn; Vial Jean-Claude; Mély Yves; Duperray Alain; Baldeck Patrice Lilian; Nicoud Jean-François
Cell-permeant cytoplasmic blue fluorophores optimized for in vivo two-photon microscopy with low-power excitation.
Microscopy research and technique 2007;70(10):880-5.
2007: Yushchenko Dmytro A; Vadzyuk Olga B; Kosterin Sergiy O; Duportail Guy; Mély Yves; Pivovarenko Vasyl G
Sensing of adenosine-5'-triphosphate anion in aqueous solutions and mitochondria by a fluorescent 3-hydroxyflavone dye.
Analytical biochemistry 2007;369(2):218-25.
2007: Yushchenko Dmytro A; Shvadchak Volodymyr V; Klymchenko Andrey S; Duportail Guy; Pivovarenko Vasyl G; Mély Yves
Steric control of the excited-state intramolecular proton transfer in 3-hydroxyquinolones: steady-state and time-resolved fluorescence study.
The journal of physical chemistry. A 2007;111(37):8986-92.
2007: Bombarda Elisa; Grell Ernst; Roques Bernard P; Mély Yves
Molecular mechanism of the Zn2+-induced folding of the distal CCHC finger motif of the HIV-1 nucleocapsid protein.
Biophysical journal 2007;93(1):208-17.
2007: Hayek Ali; Ercelen Sebnem; Zhang Xin; Bolze Frédéric; Nicoud Jean-François; Schaub Emmanuel; Baldeck Patrice L; Mély Yves
Conjugation of a new two-photon fluorophore to poly(ethylenimine) for gene delivery imaging.
Bioconjugate chemistry 2007;18(3):844-51.
2007: M'Baye Gora; Klymchenko Andrey S; Yushchenko Dmytro A; Shvadchak Volodymyr V; Ozturk Turan; Mély Yves; Duportail Guy
Fluorescent dyes undergoing intramolecular proton transfer with improved sensitivity to surface charge in lipid bilayers.
Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 2007;6(1):71-6.
2007: Tahtaoui Chouaib; Thomas Cécile; Rohmer François; Klotz Philippe; Duportail Guy; Mély Yves; Bonnet Dominique; Hibert Marcel
Convenient method to access new 4,4-dialkoxy- and 4,4-diaryloxy-diaza-s-indacene dyes: Synthesis and spectroscopic evaluation.
The Journal of organic chemistry 2007;72(1):269-72.
2007: Darlix Jean-Luc; Garrido José Luis; Morellet Nelly; Mély Yves; de Rocquigny Hugues
Properties, functions, and drug targeting of the multifunctional nucleocapsid protein of the human immunodeficiency virus.
Advances in pharmacology (San Diego, Calif.) 2007;55():299-346.
2006: Kenfack Cyril A; Burger Alain; Mély Yves
Excited-state properties and transitions of fluorescent 8-vinyl adenosine in DNA.
The journal of physical chemistry. B 2006;110(51):26327-36.
2006: Yushchenko Dmytro A; Shvadchak Volodymyr V; Bilokin' Mykhailo D; Klymchenko Andrey S; Duportail Guy; Mély Yves; Pivovarenko Vasyl G
Modulation of dual fluorescence in a 3-hydroxyquinolone dye by perturbation of its intramolecular proton transfer with solvent polarity and basicity.
Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 2006;5(11):1038-44.
2006: Ercelen Sebnem; Zhang Xin; Duportail Guy; Grandfils Christian; Desbrières Jacques; Karaeva Svetlana; Tikhonov Vladimir; Mély Yves; Babak Valery
Physicochemical properties of low molecular weight alkylated chitosans: a new class of potential nonviral vectors for gene delivery.
Colloids and surfaces. B, Biointerfaces 2006;51(2):140-8.
2006: Raja Chinappan; Ferner Jan; Dietrich Ursula; Avilov Sergiy; Ficheux Damien; Darlix Jean-Luc; de Rocquigny Hugues; Schwalbe Harald; Mély Yves
A tryptophan-rich hexapeptide inhibits nucleic acid destabilization chaperoned by the HIV-1 nucleocapsid protein.
Biochemistry 2006;45(30):9254-65.
2006: Klymchenko Andrey S; Stoeckel Herrade; Takeda Kenneth; Mély Yves
Fluorescent probe based on intramolecular proton transfer for fast ratiometric measurement of cellular transmembrane potential.
The journal of physical chemistry. B 2006;110(27):13624-32.
2006: Godet Julien; de Rocquigny Hugues; Raja Chinnappan; Glasser Nicole; Ficheux Damien; Darlix Jean-Luc; Mély Yves
During the early phase of HIV-1 DNA synthesis, nucleocapsid protein directs hybridization of the TAR complementary sequences via the ends of their double-stranded stem.
Journal of molecular biology 2006;356(5):1180-92.
2006: M'Baye Gora; Shynkar Vasyl V; Klymchenko Andrey S; Mély Yves; Duportail Guy
Membrane dipole potential as measured by ratiometric 3-hydroxyflavone fluorescence probes: accounting for hydration effects.
Journal of fluorescence 2006;16(1):35-42.
2006: Hayek Ali; Bolze Frédéric; Nicoud Jean-François; Baldeck Patrice L; Mély Yves
Synthesis and characterization of water-soluble two-photon excited blue fluorescent chromophores for bioimaging.
Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 2006;5(1):102-6.
2005: Egelé Caroline; Schaub Emmanuel; Piémont Etienne; de Rocquigny Hugues; Mély Yves
Investigation by fluorescence correlation spectroscopy of the chaperoning interactions of HIV-1 nucleocapsid protein with the viral DNA initiation sequences.
Comptes rendus biologies 2005;328(12):1041-51.
2005: Shynkar Vasyl V; Klymchenko Andrey S; Duportail Guy; Demchenko Alexander P; Mély Yves
Two-color fluorescent probes for imaging the dipole potential of cell plasma membranes.
Biochimica et biophysica acta 2005;1712(2):128-36.
2005: Ercelen Sebnem; Klymchenko Andrey S; Mély Yves; Demchenko Alexander P
The binding of novel two-color fluorescence probe FA to serum albumins of different species.
International journal of biological macromolecules 2005;35(5):231-42.
2005: Bombarda Elisa; Roques Bernard P; Mély Yves; Grell Ernst
Mechanism of zinc coordination by point-mutated structures of the distal CCHC binding motif of the HIV-1 NCp7 protein.
Biochemistry 2005;44(19):7315-25.
2005: Beltz Hervé; Clauss Céline; Piémont Etienne; Ficheux Damien; Gorelick Robert J; Roques Bernard; Gabus Caroline; Darlix Jean-Luc; de Rocquigny Hugues; Mély Yves
Structural determinants of HIV-1 nucleocapsid protein for cTAR DNA binding and destabilization, and correlation with inhibition of self-primed DNA synthesis.
Journal of molecular biology 2005;348(5):1113-26.
2005: Bourbigot Sarah; Beltz Hervé; Denis Jérôme; Morellet Nelly; Roques Bernard P; Mély Yves; Bouaziz Serge
The C-terminal domain of the HIV-1 regulatory protein Vpr adopts an antiparallel dimeric structure in solution via its leucine-zipper-like domain.
The Biochemical journal 2005;387(Pt 2):333-41.
2005: Ben Gaied Nouha; Glasser Nicole; Ramalanjaona Nick; Beltz Hervé; Wolff Philippe; Marquet Roland; Burger Alain; Mély Yves
8-vinyl-deoxyadenosine, an alternative fluorescent nucleoside analog to 2'-deoxyribosyl-2-aminopurine with improved properties.
Nucleic acids research 2005;33(3):1031-9.
2004: Klymchenko Andrey S; Mély Yves; Demchenko Alexander P; Duportail Guy
Simultaneous probing of hydration and polarity of lipid bilayers with 3-hydroxyflavone fluorescent dyes.
Biochimica et biophysica acta 2004;1665(1-2):6-19.
2004: Egelé Caroline; Schaub Emmanuel; Ramalanjaona Nick; Piémont Etienne; Ficheux Damien; Roques Bernard; Darlix Jean-Luc; Mély Yves
HIV-1 nucleocapsid protein binds to the viral DNA initiation sequences and chaperones their kissing interactions.
Journal of molecular biology 2004;342(2):453-66.
2004: Stote Roland H; Kellenberger Esther; Muller Hervé; Bombarda Elisa; Roques Bernard P; Kieffer Bruno; Mély Yves
Structure of the His44 --> Ala single point mutant of the distal finger motif of HIV-1 nucleocapsid protein: a combined NMR, molecular dynamics simulation, and fluorescence study.
Biochemistry 2004;43(24):7687-97.
2004: Klymchenko Andrey S; Duportail Guy; Demchenko Alexander P; Mély Yves
Bimodal distribution and fluorescence response of environment-sensitive probes in lipid bilayers.
Biophysical journal 2004;86(5):2929-41.
2004: Beltz Hervé; Piémont Etienne; Schaub Emmanuel; Ficheux Damien; Roques Bernard; Darlix Jean-Luc; Mély Yves
Role of the structure of the top half of HIV-1 cTAR DNA on the nucleic acid destabilizing activity of the nucleocapsid protein NCp7.
Journal of molecular biology 2004;338(4):711-23.
2004: Llères David; Weibel Jean-Marc; Heissler Denis; Zuber Guy; Duportail Guy; Mély Yves
Dependence of the cellular internalization and transfection efficiency on the structure and physicochemical properties of cationic detergent/DNA/liposomes.
The journal of gene medicine 2004;6(4):415-28.
2003: Ramos Paul; Coste Thierry; Piémont Etienne; Lessinger Jean Marc; Bousquet Jean Alain; Chapus Catherine; Kerfelec Brigitte; Férard Georges; Mély Yves
Time-resolved fluorescence allows selective monitoring of Trp30 environmental changes in the seven-Trp-containing human pancreatic lipase.
Biochemistry 2003;42(43):12488-96.
2003: Clamme Jean-Pierre; Krishnamoorthy Guruswamy; Mély Yves
Intracellular dynamics of the gene delivery vehicle polyethylenimine during transfection: investigation by two-photon fluorescence correlation spectroscopy.
Biochimica et biophysica acta 2003;1617(1-2):52-61.
2003: Pion Emmanuelle; Bombarda Elisa; Stiegler Patrick; Ullmann G Matthias; Mély Yves; de Murcia Gilbert; Gérard Dominique
Poly(ADP-ribose) polymerase-1 dimerizes at a 5' recessed DNA end in vitro: a fluorescence study.
Biochemistry 2003;42(42):12409-17.
2003: Klymchenko Andrey S; Duportail Guy; Mély Yves; Demchenko Alexander P
Ultrasensitive two-color fluorescence probes for dipole potential in phospholipid membranes.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(20):11219-24.
2003: Krishnamoorthy G; Roques Bernard; Darlix Jean-Luc; Mély Yves
DNA condensation by the nucleocapsid protein of HIV-1: a mechanism ensuring DNA protection.
Nucleic acids research 2003;31(18):5425-32.
2003: Beltz Hervé; Azoulay Joel; Bernacchi Serena; Clamme Jean-Pierre; Ficheux Damien; Roques Bernard; Darlix Jean-Luc; Mély Yves
Impact of the terminal bulges of HIV-1 cTAR DNA on its stability and the destabilizing activity of the nucleocapsid protein NCp7.
Journal of molecular biology 2003;328(1):95-108.
2003: Clamme Jean Pierre; Azoulay Joel; Mély Yves
Monitoring of the formation and dissociation of polyethylenimine/DNA complexes by two photon fluorescence correlation spectroscopy.
Biophysical journal 2003;84(3):1960-8.
2003: Azoulay Joel; Clamme Jean Pierre; Darlix Jean Luc; Roques Bernard P; Mély Yves
Destabilization of the HIV-1 complementary sequence of TAR by the nucleocapsid protein through activation of conformational fluctuations.
Journal of molecular biology 2003;326(3):691-700.
2003: Courrier H M; Krafft M P; Butz N; Porté C; Frossard N; Rémy-Kristensen A; Mély Y; Pons F; Vandamme Th F
Evaluation of cytotoxicity of new semi-fluorinated amphiphiles derived from dimorpholinophosphate.
Biomaterials 2003;24(4):689-96.
2003: Bousquet Jean-Alain; Duranton Jérôme; Mély Yves; Bieth Joseph G
Conformational change in elastase following complexation with alpha1-proteinase inhibitor: a CD investigation.
The Biochemical journal 2003;370(Pt 1):345-9.
2003: Bernacchi Serena; Piémont Etienne; Potier Noelle; Dorsselaer Alain van; Mély Yves
Excitonic heterodimer formation in an HIV-1 oligonucleotide labeled with a donor-acceptor pair used for fluorescence resonance energy transfer.
Biophysical journal 2003;84(1):643-54.
2002: Krishnamoorthy G; Duportail Guy; Mély Yves
Structure and dynamics of condensed DNA probed by 1,1'-(4,4,8,8-tetramethyl-4,8-diazaundecamethylene)bis[4-[[3- methylbenz-1,3-oxazol-2-yl]methylidine]-1,4-dihydroquinolinium] tetraiodide fluorescence.
Biochemistry 2002;41(51):15277-87.
2002: Klymchenko Andrey S; Duportail Guy; Ozturk Turan; Pivovarenko Vasyl G; Mély Yves; Demchenko Alexander P
Novel two-band ratiometric fluorescence probes with different location and orientation in phospholipid membranes.
Chemistry & biology 2002;9(11):1199-208.
2002: Mellet Philippe; Mély Yves; Hedstrom Lizbeth; Cahoon Marguerite; Belorgey Didier; Srividya Narayanan; Rubin Harvey; Bieth Joseph G
Comparative trajectories of active and S195A inactive trypsin upon binding to serpins.
The Journal of biological chemistry 2002;277(41):38901-14.
2002: Bombarda E; Cherradi H; Morellet N; Roques B P; Mély Y
Zn(2+) binding properties of single-point mutants of the C-terminal zinc finger of the HIV-1 nucleocapsid protein: evidence of a critical role of cysteine 49 in Zn(2+) dissociation.
Biochemistry 2002;41(13):4312-20.
2002: Bernacchi Serena; Stoylov Stoyl; Piémont Etienne; Ficheux Damien; Roques Bernard P; Darlix Jean Luc; Mély Yves
HIV-1 nucleocapsid protein activates transient melting of least stable parts of the secondary structure of TAR and its complementary sequence.
Journal of molecular biology 2002;317(3):385-99.
2002: Ramboarina Stéphanie; Srividya Narayanan; Atkinson R Andrew; Morellet Nelly; Roques Bernard P; Lefèvre Jean-François; Mély Yves; Kieffer Bruno
Effects of temperature on the dynamic behaviour of the HIV-1 nucleocapsid NCp7 and its DNA complex.
Journal of molecular biology 2002;316(3):611-27.
2002: Gicquiaux Hervé; Lecat Sandra; Gaire Mireille; Dieterlen Alain; Mély Yves; Takeda Kenneth; Bucher Bernard; Galzi Jean-Luc
Rapid internalization and recycling of the human neuropeptide Y Y(1) receptor.
The Journal of biological chemistry 2002;277(8):6645-55.
2001: Rémy-Kristensen A; Clamme J P; Vuilleumier C; Kuhry J G; Mély Y
Role of endocytosis in the transfection of L929 fibroblasts by polyethylenimine/DNA complexes.
Biochimica et biophysica acta 2001;1514(1):21-32.
2001: Bombarda E; Morellet N; Cherradi H; Spiess B; Bouaziz S; Grell E; Roques B P; Mély Y
Determination of the pK(a) of the four Zn2+-coordinating residues of the distal finger motif of the HIV-1 nucleocapsid protein: consequences on the binding of Zn2+.
Journal of molecular biology 2001;310(3):659-72.
2001: Bernacchi S; Mély Y
Exciton interaction in molecular beacons: a sensitive sensor for short range modifications of the nucleic acid structure.
Nucleic acids research 2001;29(13):E62-2.
2001: Lleres D; Dauty E; Behr J P; Mély Y; Duportail G
DNA condensation by an oxidizable cationic detergent. Interactions with lipid vesicles.
Chemistry and physics of lipids 2001;111(1):59-71.
2000: Clamme J P; Bernacchi S; Vuilleumier C; Duportail G; Mély Y
Gene transfer by cationic surfactants is essentially limited by the trapping of the surfactant/DNA complexes onto the cell membrane: a fluorescence investigation.
Biochimica et biophysica acta 2000;1467(2):347-61.
2000: Bousquet J A; Garbay C; Roques B P; Mély Y
Circular dichroic investigation of the native and non-native conformational states of the growth factor receptor-binding protein 2 N-terminal src homology domain 3: effect of binding to a proline-rich peptide from guanine nucleotide exchange factor.
Biochemistry 2000;39(26):7722-35.
1999: Vuilleumier C; Bombarda E; Morellet N; Gérard D; Roques B P; Mély Y
Nucleic acid sequence discrimination by the HIV-1 nucleocapsid protein NCp7: a fluorescence study.
Biochemistry 1999;38(51):16816-25.
1999: Bombarda E; Ababou A; Vuilleumier C; Gérard D; Roques B P; Piémont E; Mély Y
Time-resolved fluorescence investigation of the human immunodeficiency virus type 1 nucleocapsid protein: influence of the binding of nucleic acids.
Biophysical journal 1999;76(3):1561-70.
1998: Le Cam E; Coulaud D; Delain E; Petitjean P; Roques B P; Gérard D; Stoylova E; Vuilleumier C; Stoylov S P; Mély Y
Properties and growth mechanism of the ordered aggregation of a model RNA by the HIV-1 nucleocapsid protein: an electron microscopy investigation.
Biopolymers 1998;45(3):217-29.
1997: Mély Y; Cadène M; Sylte I; Bieth J G
Mapping the suramin-binding sites of human neutrophil elastase: investigation by fluorescence resonance energy transfer and molecular modeling.
Biochemistry 1997;36(50):15624-31.
1997: Stoylov S P; Vuilleumier C; Stoylova E; De Rocquigny H; Roques B P; Gérard D; Mély Y
Ordered aggregation of ribonucleic acids by the human immunodeficiency virus type 1 nucleocapsid protein.
Biopolymers 1997;41(3):301-12.
1997: Vuilleumier C; Maechling-Strasser C; Gérard D; Mély Y
Evidence and prevention of HIV-1 nucleocapsid protein adsorption onto fluorescence quartz cells.
Analytical biochemistry 1997;244(1):183-5.
1996: Mély Y; De Rocquigny H; Morellet N; Roques B P; Gérad D
Zinc binding to the HIV-1 nucleocapsid protein: a thermodynamic investigation by fluorescence spectroscopy.
Biochemistry 1996;35(16):5175-82.
1995: Mély Y; de Rocquigny H; Sorinas-Jimeno M; Keith G; Roques B P; Marquet R; Gérard D
Binding of the HIV-1 nucleocapsid protein to the primer tRNA(3Lys), in vitro, is essentially not specific.
The Journal of biological chemistry 1995;270(4):1650-6.
1994: Mély Y; Jullian N; Morellet N; De Rocquigny H; Dong C Z; Piémont E; Roques B P; Gérard D
Spatial proximity of the HIV-1 nucleocapsid protein zinc fingers investigated by time-resolved fluorescence and fluorescence resonance energy transfer.
Biochemistry 1994;33(40):12085-91.
1994: Morellet N; de Rocquigny H; Mély Y; Jullian N; Déméné H; Ottmann M; Gérard D; Darlix J L; Fournie-Zaluski M C; Roques B P
Conformational behaviour of the active and inactive forms of the nucleocapsid NCp7 of HIV-1 studied by 1H NMR.
Journal of molecular biology 1994;235(1):287-301.
1993: Mély Y; Piémont E; Sorinas-Jimeno M; de Rocquigny H; Jullian N; Morellet N; Roques B P; Gérard D
Structural and dynamic characterization of the aromatic amino acids of the human immunodeficiency virus type I nucleocapsid protein zinc fingers and their involvement in heterologous tRNA(Phe) binding: a steady-state and time-resolved fluorescence study.
Biophysical journal 1993;65(4):1513-22.

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