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Michael Menconi

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Anatomy

Physiology

Cell Membrane Permeability

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Michael Menconi; Zoltan P Arany; Nima Alamdari; Zaira Aversa; Patricia Gonnella; Patrick O'Neal; Ira J Smith; Steven Tizio; Per-Olof Hasselgren
Sepsis and glucocorticoids downregulate the expression of the nuclear cofactor PGC-1beta in skeletal muscle.
Patrick O'Neal; Nima Alamdari; Ira Smith; Vitaliy Poylin; Michael Menconi; Per-Olof Hasselgren
Experimental hyperthyroidism in rats increases the expression of the ubiquitin ligases atrogin-1 and MuRF1 and stimulates multiple proteolytic pathways in skeletal muscle.
Michael Menconi; Patricia Gonnella; Victoria Petkova; Stewart Lecker; Per-Olof Hasselgren
Dexamethasone and corticosterone induce similar, but not identical, muscle wasting responses in cultured L6 and C2C12 myotubes.

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All Publications

2010: Michael Menconi; Zoltan P Arany; Nima Alamdari; Zaira Aversa; Patricia Gonnella; Patrick O'Neal; Ira J Smith; Steven Tizio; Per-Olof Hasselgren
Sepsis and glucocorticoids downregulate the expression of the nuclear cofactor PGC-1beta in skeletal muscle.
American journal of physiology. Endocrinology and metabolism 2010;299(4):E533-43.
2009: Patrick O'Neal; Nima Alamdari; Ira Smith; Vitaliy Poylin; Michael Menconi; Per-Olof Hasselgren
Experimental hyperthyroidism in rats increases the expression of the ubiquitin ligases atrogin-1 and MuRF1 and stimulates multiple proteolytic pathways in skeletal muscle.
Journal of cellular biochemistry 2009;108(4):963-73.
2008: Michael Menconi; Patricia Gonnella; Victoria Petkova; Stewart Lecker; Per-Olof Hasselgren
Dexamethasone and corticosterone induce similar, but not identical, muscle wasting responses in cultured L6 and C2C12 myotubes.
Journal of cellular biochemistry 2008;105(2):353-64.
2008: Vitaliy Poylin; Moin U Fareed; Patrick O'Neal; Nima Alamdari; Natasha Reilly; Michael Menconi; Per-Olof Hasselgren
The NF-kappaB inhibitor curcumin blocks sepsis-induced muscle proteolysis.
Mediators of inflammation 2008;2008():317851.
2007: Michael Menconi; Moin U Fareed; Patrick O'Neal; Vitaliy Poylin; Wei Wei; Per-Olof Hasselgren
Role of glucocorticoids in the molecular regulation of muscle wasting.
Critical care medicine 2007;35(9 Suppl):S602-8.
2007: Natasha Reilly; Vitaliy Poylin; Michael Menconi; Andrew B Onderdonk; Stig Bengmark; Per-Olof Hasselgren
Probiotics potentiate IL-6 production in IL-1beta-treated Caco-2 cells through a heat shock-dependent mechanism.
American journal of physiology. Regulatory, integrative and comparative physiology 2007;293(3):R1169-79.
2007: Wei Wei; Hongmei Yang; Michael Menconi; Peirang Cao; Chester E Chamberlain; Per-Olof Hasselgren
Treatment of cultured myotubes with the proteasome inhibitor beta-lactone increases the expression of the transcription factor C/EBPbeta.
American journal of physiology. Cell physiology 2007;292(1):C216-26.
2007: Hongmei Yang; Wei Wei; Michael Menconi; Per-Olof Hasselgren
Dexamethasone-induced protein degradation in cultured myotubes is p300/HAT dependent.
American journal of physiology. Regulatory, integrative and comparative physiology 2007;292(1):R337-4.
2006: Wei Wei; Hongmei Yang; Peirang Cao; Michael Menconi; Chester Chamberlain; Victoria Petkova; Per-Olof Hasselgren
Degradation of C/EBPbeta in cultured myotubes is calpain-dependent.
Journal of cellular physiology 2006;208(2):386-98.
2006: Moin U Fareed; Amy R Evenson; Wei Wei; Michael Menconi; Vitaliy Poylin; Victoria Petkova; Bernadette Pignol; Per-Olof Hasselgren
Treatment of rats with calpain inhibitors prevents sepsis-induced muscle proteolysis independent of atrogin-1/MAFbx and MuRF1 expression.
American journal of physiology. Regulatory, integrative and comparative physiology 2006;290(6):R1589-97.
2005: Per-Olof Hasselgren; Michael Menconi; Moin U Fareed; Hongmei Yang; Wei Wei; Amy R Evenson
Novel aspects on the regulation of muscle wasting in sepsis.
The international journal of biochemistry & cell biology 2005;37(10):2156-68.
2005: Amy R Evenson; Moin U Fareed; Michael Menconi; Jamie C Mitchell; Per-Olof Hasselgren
GSK-3beta inhibitors reduce protein degradation in muscles from septic rats and in dexamethasone-treated myotubes.
The international journal of biochemistry & cell biology 2005;37(10):2226-38.
2005: Hongmei Yang; Joshua M V Mammen; Wei Wei; Michael Menconi; Amy R Evenson; Moin U Fareed; Victoria Petkova; Per-Olof Hasselgren
Expression and activity of C/EBPbeta and delta are upregulated by dexamethasone in skeletal muscle.
Journal of cellular physiology 2005;204(1):219-26.
2005: Hongmei Yang; Michael Menconi; Wei Wei; Victoria Petkova; Per-Olof Hasselgren
Dexamethasone upregulates the expression of the nuclear cofactor p300 and its interaction with C/EBPbeta in cultured myotubes.
Journal of cellular biochemistry 2005;94(5):1058-67.
2005: Wei Wei; Moin U Fareed; Amy R Evenson; Michael Menconi; Hongmei Yang; Victoria Petkova; Per-Olof Hasselgren
Sepsis stimulates calpain activity in skeletal muscle by decreasing calpastatin activity but does not activate caspase-3.
American journal of physiology. Regulatory, integrative and comparative physiology 2005;288(3):R580-90.
2004: Julio A Clavijo-Alvarez; Carrie A Sims; Michael Menconi; Inbo Shim; Christian Ochoa; Juan Carlos Puyana
Bladder mucosa pH and Pco2 as a minimally invasive monitor of hemorrhagic shock and resuscitation.
The Journal of trauma 2004;57(6):1199-209; discussion 1209-10.
2004: Michael Menconi; Wei Wei; Hongmei Yang; Curtis J Wray; Per-Olof Hasselgren
Treatment of cultured myotubes with the calcium ionophore A23187 increases proteasome activity via a CaMK II-caspase-calpain-dependent mechanism.
Surgery 2004;136(2):135-42.
2001: C Sims; P Seigne; Michael Menconi; J Monarca; C Barlow; J Pettit; Juan Carlos Puyana
Skeletal muscle acidosis correlates with the severity of blood volume loss during shock and resuscitation.
The Journal of trauma 2001;51(6):1137-45; discussion 1145-6.
2001: C A Sims; S Wattanasirichaigoon; Michael Menconi; Alfred Ajami; Mitchell Fink
Ringer's ethyl pyruvate solution ameliorates ischemia/reperfusion-induced intestinal mucosal injury in rats.
Critical care medicine 2001;29(8):1513-8.
2000: S Wattanasirichaigoon; Michael Menconi; Mitchell Fink
Lisofylline ameliorates intestinal and hepatic injury induced by hemorrhage and resuscitation in rats.
Critical care medicine 2000;28(5):1540-9.
2000: M Tomita; Michael Menconi; Russell L Delude; Mitchell Fink
Polarized transport of hydrophilic compounds across rat colonic mucosa from serosa to mucosa is temperature dependent.
Gastroenterology 2000;118(3):535-43.
1999: AM Chavez; Michael Menconi; Richard A Hodin; Mitchell Fink
Cytokine-induced intestinal epithelial hyperpermeability: role of nitric oxide.
Critical care medicine 1999;27(10):2246-51.
1999: S Wattanasirichaigoon; Michael Menconi; Russell L Delude; Mitchell Fink
Effect of mesenteric ischemia and reperfusion or hemorrhagic shock on intestinal mucosal permeability and ATP content in rats.
Shock (Augusta, Ga.) 1999;12(2):127-33.
1999: S Wattanasirichaigoon; Michael Menconi; Russell L Delude; Mitchell Fink
Lisofylline ameliorates intestinal mucosal barrier dysfunction caused by ischemia and ischemia/reperfusion.
Shock (Augusta, Ga.) 1999;11(4):269-75.
1998: Michael Menconi; N Unno; M Smith; DE Aguirre; Mitchell Fink
Nitric oxide donor-induced hyperpermeability of cultured intestinal epithelial monolayers: role of superoxide radical, hydroxyl radical, and peroxynitrite.
Biochimica et biophysica acta 1998;1425(1):189-203.
1997: N Unno; H Wang; Michael Menconi; S H Tytgat; V Larkin; M Smith; MJ Morin; AM Chavez; Richard A Hodin; Mitchell Fink
Inhibition of inducible nitric oxide synthase ameliorates endotoxin-induced gut mucosal barrier dysfunction in rats.
Gastroenterology 1997;113(4):1246-57.
1997: N Unno; Michael Menconi; Mitchell Fink
Nitric oxide-induced hyperpermeability of human intestinal epithelial monolayers is augmented by inhibition of the amiloride-sensitive Na(+)-H+ antiport: potential role of peroxynitrous acid.
Surgery 1997;122(2):485-91; discussion 491-2.
1997: N Unno; Michael Menconi; M Smith; S J Hagen; D A Brown; DE Aguirre; Mitchell Fink
Acidic conditions ameliorate both adenosine triphosphate depletion and the development of hyperpermeability in cultured Caco-2BBe enterocytic monolayers subjected to metabolic inhibition.
Surgery 1997;121(6):668-80.
1997: Michael Menconi; A L Salzman; N Unno; Robert Ezzell; D M Casey; D A Brown; Y Tsuji; Mitchell Fink
Acidosis induces hyperpermeability in Caco-2BBe cultured intestinal epithelial monolayers.
The American journal of physiology 1997;272(5 Pt 1):G1007-21.
1997: N Unno; Michael Menconi; M Smith; DE Aguirre; Mitchell Fink
Hyperpermeability of intestinal epithelial monolayers is induced by NO: effect of low extracellular pH.
The American journal of physiology 1997;272(5 Pt 1):G923-34.
1996: E M Cameron; J Zhuang; Michael Menconi; Roger Phipps; Mitchell Fink
Dantrolene, an inhibitor of intracellular calcium release, fails to increase survival in a rat model of intra-abdominal sepsis.
Critical care medicine 1996;24(9):1537-42.
1996: Y Tsuji; N Unno; Michael Menconi; M Smith; Mitchell Fink
Nitric oxide donors increase cytosolic ionized calcium in cultured human intestinal epithelial cells.
Shock (Augusta, Ga.) 1996;6(1):19-24.
1996: N Unno; Michael Menconi; A L Salzman; M Smith; S Hagen; Y Ge; Robert Ezzell; Mitchell Fink
Hyperpermeability and ATP depletion induced by chronic hypoxia or glycolytic inhibition in Caco-2BBe monolayers.
The American journal of physiology 1996;270(6 Pt 1):G1010-21.
1996: P K Gonzalez; J Zhuang; Susan R Doctrow; Bernard Malfroy; P F Benson; Michael Menconi; Mitchell Fink
Role of oxidant stress in the adult respiratory distress syndrome: evaluation of a novel antioxidant strategy in a porcine model of endotoxin-induced acute lung injury.
Shock (Augusta, Ga.) 1996;6 Suppl 1():S23-6.
1995: P K Gonzalez; J Zhuang; Susan R Doctrow; Bernard Malfroy; P F Benson; Michael Menconi; Mitchell Fink
EUK-8, a synthetic superoxide dismutase and catalase mimetic, ameliorates acute lung injury in endotoxemic swine.
The Journal of pharmacology and experimental therapeutics 1995;275(2):798-806.
1995: N Unno; Michael Menconi; M Smith; Mitchell Fink
Nitric oxide mediates interferon-gamma-induced hyperpermeability in cultured human intestinal epithelial monolayers.
Critical care medicine 1995;23(7):1170-6.
1995: T J VanderMeer; Michael Menconi; J Zhuang; H Wang; R Murtaugh; C Bouza; P Stevens; Mitchell Fink
Protective effects of a novel 32-amino acid C-terminal fragment of CAP18 in endotoxemic pigs.
Surgery 1995;117(6):656-62.
1995: T J VanderMeer; Michael Menconi; B P O'Sullivan; V A Larkin; H Wang; M Sofia; Mitchell Fink
Acute lung injury in endotoxemic pigs: role of leukotriene B4.
Journal of applied physiology (Bethesda, Md. : 1985) 1995;78(3):1121-31.
1995: Michael Menconi; Shirwin M Pockwinse; Thomas A Owen; K A Dasse; Gary S Stein; Jane B Lian
Properties of blood-contacting surfaces of clinically implanted cardiac assist devices: gene expression, matrix composition, and ultrastructural characterization of cellular linings.
Journal of cellular biochemistry 1995;57(3):557-73.
1995: A L Salzman; Michael Menconi; N Unno; Robert Ezzell; D M Casey; P K Gonzalez; Mitchell Fink
Nitric oxide dilates tight junctions and depletes ATP in cultured Caco-2BBe intestinal epithelial monolayers.
The American journal of physiology 1995;268(2 Pt 1):G361-73.
1994: P S Wollert; Michael Menconi; H Wang; B P O'Sullivan; V Larkin; Robert Allen; Mitchell Fink
Prior exposure to endotoxin exacerbates lipopolysaccharide-induced hypoxemia and alveolitis in anesthetized swine.
Shock (Augusta, Ga.) 1994;2(5):362-9.
1994: Jeffrey B Matthews; J A Smith; K J Tally; Michael Menconi; H Nguyen; Mitchell Fink
Chemical hypoxia increases junctional permeability and activates electrogenic ion transport in human intestinal epithelial monolayers.
Surgery 1994;116(2):150-7; discussion 157-8.
1994: T J Vandermeer; Michael Menconi; B P O'Sullivan; V A Larkin; H Wang; Richard L Kradin; Mitchell Fink
Bactericidal/permeability-increasing protein ameliorates acute lung injury in porcine endotoxemia.
Journal of applied physiology (Bethesda, Md. : 1985) 1994;76(5):2006-14.
1993: Mitchell Fink; B P O'Sullivan; Michael Menconi; P S Wollert; H Wang; M E Youssef; J H Fleisch
A novel leukotriene B4-receptor antagonist in endotoxin shock: a prospective, controlled trial in a porcine model.
Critical care medicine 1993;21(12):1825-37.
1993: P S Wollert; Michael Menconi; B P O'Sullivan; H Wang; V Larkin; Mitchell Fink
LY255283, a novel leukotriene B4 receptor antagonist, limits activation of neutrophils and prevents acute lung injury induced by endotoxin in pigs.
Surgery 1993;114(2):191-8.
1993: J M Li; Michael Menconi; H B Wheeler; Michael J Rohrer; Frederick A Anderson; Bruce S Cutler
Experimental femoral vein reconstruction with expanded polytetrafluoroethylene grafts seeded with endothelial cells.
Cardiovascular surgery (London, England) 1993;1(4):362-8.
1993: A Salzman; P S Wollert; H Wang; Michael Menconi; M E Youssef; Carolyn Corlies Compton; Mitchell Fink
Intraluminal oxygenation ameliorates ischemia/reperfusion-induced gut mucosal hyperpermeability in pigs.
Circulatory shock 1993;40(1):37-46.
1993: Mitchell Fink; B P O'Sullivan; Michael Menconi; S P Wollert; H Wang; M E Youssef; J M Bellelsle
Effect of granulocyte colony-stimulating factor on systemic and pulmonary responses to endotoxin in pigs.
The Journal of trauma 1993;34(4):571-7; discussion 577-8.
1992: Michael Menconi; T Owen; K A Dasse; G Stein; Jane B Lian
Molecular approaches to the characterization of cell and blood/biomaterial interactions.
Journal of cardiac surgery 1992;7(2):177-87.
1992: J M Li; Michael Menconi; H B Wheeler; Michael J Rohrer; V A Klassen; J E Ansell; M C Appel
Precoating expanded polytetrafluoroethylene grafts alters production of endothelial cell-derived thrombomodulators.
Journal of vascular surgery 1992;15(6):1010-7.