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Josefina Méndez

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Maria Prado-Alvarez; Fernanda Flórez-Barrós; Josefina Méndez; Juan Fernandez-Tajes
Effect of okadaic acid on carpet shell clam (Ruditapes decussatus) haemocytes by in vitro exposure and harmful algal bloom simulation assays.
Vanessa Valdiglesias; Juan Fernández-Tajes; Josefina Méndez; Eduardo Pásaro; Blanca Laffon
The marine toxin okadaic acid induces alterations in the expression level of cancer-related genes in human neuronal cells.
Ginna Chacón; Ana Insua; Josefina Méndez; Alberto Arias-Pérez; Ruth Freire
Development and multiplex PCR amplification of microsatellite markers in the commercial clam Venerupis rhomboides (Mollusca: Bivalvia).

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2013: Maria Prado-Alvarez; Fernanda Flórez-Barrós; Josefina Méndez; Juan Fernandez-Tajes
Effect of okadaic acid on carpet shell clam (Ruditapes decussatus) haemocytes by in vitro exposure and harmful algal bloom simulation assays.
Cell biology and toxicology 2013;29(3):189-97.
2013: Vanessa Valdiglesias; Juan Fernández-Tajes; Josefina Méndez; Eduardo Pásaro; Blanca Laffon
The marine toxin okadaic acid induces alterations in the expression level of cancer-related genes in human neuronal cells.
Ecotoxicology and environmental safety 2013;92():303-11.
2013: Ginna Chacón; Ana Insua; Josefina Méndez; Alberto Arias-Pérez; Ruth Freire
Development and multiplex PCR amplification of microsatellite markers in the commercial clam Venerupis rhomboides (Mollusca: Bivalvia).
Molecular biology reports 2013;40(2):1625-30.
2013: Victoria Suárez-Ulloa; Vanessa Aguiar-Pulido; Juan Ausio; Julián Dorado; Juan Fernández-Tajes; Rodrigo González-Romero; Josefina Méndez; Ciro Rivera-Casas; Jose Maria Eirín-López
The CHROMEVALOA Database: A Resource for the Evaluation of Okadaic Acid Contamination in the Marine Environment Based on the Chromatin-Associated Transcriptome of the Mussel Mytilus galloprovincialis.
Marine drugs 2013;11(3):830-41.
2012: Maria Prado-Alvarez; Alexia Sexto-Iglesias; Fernanda Flórez-Barrós; Josefina Méndez; Juan Fernandez-Tajes
Effects of okadaic acid on haemocytes from Mytilus galloprovincialis: a comparison between field and laboratory studies.
Marine environmental research 2012;81():90-3.
2012: Julia García-Lestón; Jorge Francisco Gaspar; João Conde; Olga Mayan; Josefina Méndez; Eduardo Pásaro; Marta Pingarilho; Rui Pinto; João Prista; Joana Roma-Torres; Joao Paulo Teixeira; Maria Vilares; Blanca Laffon
Genotoxic effects of occupational exposure to lead and influence of polymorphisms in genes involved in lead toxicokinetics and in DNA repair.
Environment international 2012;43():29-36.
2012: Alberto Arias-Pérez; Juan Fernández-Tajes; Miguel B Gaspar; Josefina Méndez
Isolation of microsatellite markers and analysis of genetic diversity among east Atlantic populations of the sword razor shell Ensis siliqua: a tool for population management.
Biochemical genetics 2012;50(5-6):397-415.
2012: Vanessa Valdiglesias; Carla Costa; Juan Fernández-Tajes; Josefina Méndez; Eduardo Pásaro; Blanca Laffon
Alterations in metabolism-related genes induced in SHSY5Y cells by okadaic acid exposure.
Journal of toxicology and environmental health. Part A 2012;75(13-15):844-56.
2012: Julia García-Lestón; Dietmar Fuchs; Olga Mayan; Josefina Méndez; Ana O Moreira; Eduardo Pásaro; Joana Roma-Torres; Sebastian Schroecksnadel; Joao Paulo Teixeira; Blanca Laffon
Assessment of immunotoxicity parameters in individuals occupationally exposed to lead.
Journal of toxicology and environmental health. Part A 2012;75(13-15):807-18.
2012: Vanessa Valdiglesias; Óscar Amor-Carro; Carla Costa; Gözde Kiliç; Luis Mariñas-Pardo; Josefina Méndez; Eduardo Pásaro; David Ramos-Barbón; Blanca Laffon
In vivo genotoxicity assessment in rats exposed to Prestige-like oil by inhalation.
Journal of toxicology and environmental health. Part A 2012;75(13-15):756-64.
2012: Vanessa Valdiglesias; Juan Fernández-Tajes; Josefina Méndez; Eduardo Pásaro; Blanca Laffon
Identification of differentially expressed genes in SHSY5Y cells exposed to okadaic acid by suppression subtractive hybridization.
BMC genomics 2012;13():46.
2012: Rodrigo González-Romero; Josefina Méndez; Ciro Rivera-Casas; Juan Ausió; Lindsay J Frehlick; Jose Maria Eirín-López
Histone H2A (H2A.X and H2A.Z) variants in molluscs: molecular characterization and potential implications for chromatin dynamics.
PloS one 2012;7(1):e30006.
2011: Vanessa Valdiglesias; Eduardo Pásaro; Blanca Laffon; Josefina Méndez
Okadaic acid induces morphological changes, apoptosis and cell cycle alterations in different human cell types.
Journal of environmental monitoring : JEM 2011;13(6):1831-40.
2011: Juan Fernández-Tajes; Fernanda Flórez; Sandra Pereira; Tamara Rábade; Blanca Laffon; Josefina Méndez
Use of three bivalve species for biomonitoring a polluted estuarine environment.
Environmental monitoring and assessment 2011;177(1-4):289-300.
2011: Vanessa Valdiglesias; Blanca Laffon; Eduardo Pásaro; Eduardo Cemeli; Diana Anderson; Josefina Méndez
Induction of oxidative DNA damage by the marine toxin okadaic acid depends on human cell type.
Toxicon : official journal of the International Society on Toxinology 2011;57(6):882-8.
2011: Alberto Arias; Ruth Freire; Juan Pablo De La Roche; Guillermo Román; Josefina Méndez; Ana Insua
Identification, inheritance, and variation of microsatellite markers in the black scallop Mimachlamys varia.
Biochemical genetics 2011;49(3-4):139-52.
2011: Julia García-Lestón; Joana Roma-Torres; Maria Vilares; Rui Pinto; Luís M Cunha; João Prista; Joao Paulo Teixeira; Olga Mayan; Eduardo Pásaro; Josefina Méndez; Blanca Laffon
Biomonitoring of a population of Portuguese workers exposed to lead.
Mutation research 2011;721(1):81-8.
2011: Vanessa Valdiglesias; Josefina Méndez; Eduardo Pásaro; Blanca Laffon
Assays to determine DNA repair ability.
Journal of toxicology and environmental health. Part A 2011;74(15-16):1094-109.
2011: Juan Fernández-Tajes; Blanca Laffon; Tamara Rábade; Josefina Méndez
Monitoring follow up of two areas affected by the Prestige oil four years after the spillage.
Journal of toxicology and environmental health. Part A 2011;74(15-16):1067-75.
2011: Sandra M Pereira; Tamara Rábade; Juan Fernández-Tajes; Fernanda Flórez-Barrós; Blanca Laffon; Josefina Méndez
Comparison between two bivalve species as tools for the assessment of pollution levels in an estuarian environment.
Journal of toxicology and environmental health. Part A 2011;74(15-16):1020-9.
2011: Vanessa Valdiglesias; Eduardo Pásaro; Blanca Laffon; Josefina Méndez
Evaluation of okadaic acid-induced genotoxicity in human cells using the micronucleus test and γH2AX analysis.
Journal of toxicology and environmental health. Part A 2011;74(15-16):980-92.
2011: Fernanda Flórez-Barrós; Josefina Méndez; María Prado-Alvarez; Juan Fernández-Tajes
Evaluation of genotoxicity in gills and hemolymph of clam Ruditapes decussatus fed with the toxic dinoflagellate Prorocentrum lima.
Journal of toxicology and environmental health. Part A 2011;74(15-16):971-9.
2010: Julia García-Lestón; Josefina Méndez; Eduardo Pásaro; Blanca Laffon
Genotoxic effects of lead: an updated review.
Environment international 2010;36(6):623-36.
2010: Vanessa Valdiglesias; Josefina Méndez; Eduardo Pásaro; Eduardo Cemeli; Diana Anderson; Blanca Laffon
Assessment of okadaic acid effects on cytotoxicity, DNA damage and DNA repair in human cells.
Mutation research 2010;689(1-2):74-9.
2010: Francisco Aguilera; Josefina Méndez; Eduardo Pásaro; Blanca Laffon
Review on the effects of exposure to spilled oils on human health.
Journal of applied toxicology : JAT 2010;30(4):291-301.
2010: Vanessa Valdiglesias; Eduardo Pásaro; Josefina Méndez; Blanca Laffon
In vitro evaluation of selenium genotoxic, cytotoxic, and protective effects: a review.
Archives of toxicology 2010;84(5):337-51.
2010: Blanca Laffon; Vanessa Valdiglesias; Eduardo Pásaro; Josefina Méndez
The organic selenium compound selenomethionine modulates bleomycin-induced DNA damage and repair in human leukocytes.
Biological trace element research 2010;133(1):12-9.
2009: Juan Fernández-Tajes; Josefina Méndez
Two different size classes of 5S rDNA units coexisting in the same tandem array in the razor clam Ensis macha: is this region suitable for phylogeographic studies?
Biochemical genetics 2009;47(11-12):775-88.
2009: Alberto Arias; Ruth Freire; Josefina Méndez; Ana Insua
Intron characterization and their potential as molecular markers for population studies in the scallops Aequipecten opercularis and Mimachlamys varia.
Hereditas 2009;146(2):46-57.
2008: Beatriz Pérez-Cadahía; Blanca Laffon; Vanessa Valdiglesias; Eduardo Pásaro; Josefina Méndez
Cytogenetic effects induced by Prestige oil on human populations: the role of polymorphisms in genes involved in metabolism and DNA repair.
Mutation research 2008;653(1-2):117-23.
2008: Rodrigo González-Romero; Juan Ausió; Josefina Méndez; Jose Maria Eirín-López
Early evolution of histone genes: prevalence of an 'orphon' H1 lineage in protostomes and birth-and-death process in the H2A family.
Journal of molecular evolution 2008;66(5):505-18.
2008: Rodrigo González-Romero; Josefina Méndez; Juan Ausió; Jose Maria Eirín-López
Quickly evolving histones, nucleosome stability and chromatin folding: all about histone H2A.Bbd.
Gene 2008;413(1-2):1-7.
2008: Beatriz Pérez-Cadahía; Blanca Laffon; Miquel Porta; Anunciación Lafuente; Teresa Cabaleiro; Tomàs López; Ana Caride; José Pumarega; Alejandro Romero; Eduardo Pásaro; Josefina Méndez
Relationship between blood concentrations of heavy metals and cytogenetic and endocrine parameters among subjects involved in cleaning coastal areas affected by the 'Prestige' tanker oil spill.
Chemosphere 2008;71(3):447-55.
2008: María José López-Piñón; Ruth Freire; Ana Insua; Josefina Méndez
Sequence characterization and phylogenetic analysis of the 5S ribosomal DNA in some scallops (Bivalvia: Pectinidae).
Hereditas 2008;145(1):9-19.
2008: Beatriz Pérez-Cadahía; Josefina Méndez; Eduardo Pásaro; Anunciación Lafuente; Teresa Cabaleiro; Blanca Laffon
Biomonitoring of human exposure to prestige oil: effects on DNA and endocrine parameters.
Environmental health insights 2008;2():83-92.
2007: Juan Fernandez-Tajes; Josefina Méndez
Identification of the razor clam species Ensis arcuatus, E. siliqua, E. directus, E. macha, and Solen marginatus using PCR-RFLP analysis of the 5S rDNA region.
Journal of agricultural and food chemistry 2007;55(18):7278-82.
2007: Beatriz Pérez-Cadahía; Vanessa Valdiglesias; Eduardo Pásaro; Josefina Méndez; Blanca Laffon
Genetic polymorphism in cytochrome P450 1B1 in a Spanish population.
Basic & clinical pharmacology & toxicology 2007;101(1):70-2.
2007: Beatriz Pérez-Cadahía; Anunciación Lafuente; Teresa Cabaleiro; Eduardo Pásaro; Josefina Méndez; Blanca Laffon
Initial study on the effects of Prestige oil on human health.
Environment international 2007;33(2):176-85.
2006: Blanca Laffon; Rebeca Fraga-Iriso; Beatriz Pérez-Cadahía; Josefina Méndez
Genotoxicity associated to exposure to Prestige oil during autopsies and cleaning of oil-contaminated birds.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2006;44(10):1714-23.
2006: Blanca Laffon; Joao Paulo Teixeira; Susana Silva; Joana Roma-Torres; Beatriz Pérez-Cadahía; Josefina Méndez; Eduardo Pásaro; Olga Mayan
Assessment of occupational genotoxic risk in the production of rubber tyres.
The Annals of occupational hygiene 2006;50(6):583-92.
2006: Joana Roma-Torres; Joao Paulo Teixeira; Susana Silva; Blanca Laffon; Luís M Cunha; Josefina Méndez; Olga Mayan
Evaluation of genotoxicity in a group of workers from a petroleum refinery aromatics plant.
Mutation research 2006;604(1-2):19-27.
2006: Blanca Laffon; Tamara Rábade; Eduardo Pásaro; Josefina Méndez
Monitoring of the impact of Prestige oil spill on Mytilus galloprovincialis from Galician coast.
Environment international 2006;32(3):342-8.
2006: Ana Insua; María José López-Piñón; Ruth Freire; Josefina Méndez
Karyotype and chromosomal location of 18S-28S and 5S ribosomal DNA in the scallops Pecten maximus and Mimachlamys varia (Bivalvia: Pectinidae).
Genetica 2006;126(3):291-301.
2006: Beatriz Pérez-Cadahía; Blanca Laffon; Eduardo Pásaro; Josefina Méndez
Genetic damage induced by accidental environmental pollutants.
TheScientificWorldJournal 2006;6():1221-37.
2005: Jose Maria Eirín-López; M Fernanda Ruiz; Ana M González-Tizón; Andrés Martínez; Juan Ausió; Lucas Sánchez; Josefina Méndez
Common evolutionary origin and birth-and-death process in the replication-independent histone H1 isoforms from vertebrate and invertebrate genomes.
Journal of molecular evolution 2005;61(3):398-407.
2005: Blanca Laffon; Joao Paulo Teixeira; Susana Silva; J Loureiro; J Torres; Eduardo Pásaro; Josefina Méndez; Olga Mayan
Genotoxic effects in a population of nurses handling antineoplastic drugs, and relationship with genetic polymorphisms in DNA repair enzymes.
American journal of industrial medicine 2005;48(2):128-36.
2005: Ruth Freire; Ana Insua; Josefina Méndez
Cerastoderma glaucum 5S ribosomal DNA: characterization of the repeat unit, divergence with respect to Cerastoderma edule, and PCR-RFLPs for the identification of both cockles.
Genome / National Research Council Canada = Génome / Conseil national de recherches Canada 2005;48(3):427-42.
2005: Andrés Martínez-Lage; F Rodríguez-Fariña; Ana M González-Tizón; Josefina Méndez
Origin and evolution of Mytilus mussel satellite DNAs.
Genome / National Research Council Canada = Génome / Conseil national de recherches Canada 2005;48(2):247-56.
2005: María José López-Piñón; Ana Insua; Josefina Méndez
Chromosome analysis and mapping of ribosomal genes by one- and two-color fluorescent in situ hybridization in Hinnites distortus (Bivalvia: Pectinidae).
The Journal of heredity 2005;96(1):52-8.
2004: Jose Maria Eirín-López; Ana M González-Tizón; Andrés Martínez; Josefina Méndez
Birth-and-death evolution with strong purifying selection in the histone H1 multigene family and the origin of orphon H1 genes.
Molecular biology and evolution 2004;21(10):1992-2003.
2004: Beatriz Pérez-Cadahía; Blanca Laffon; Eduardo Pásaro; Josefina Méndez
Evaluation of PAH bioaccumulation and DNA damage in mussels (Mytilus galloprovincialis) exposed to spilled Prestige crude oil.
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 2004;138(4):453-60.
2004: Joao Paulo Teixeira; Jorge Gaspar; Susana Silva; Joana Torres; Susana N Silva; M Conceição Azevedo; Paula Neves; Blanca Laffon; Josefina Méndez; Carla Gonçalves; Olga Mayan; Peter B Farmer; Jose Rueff
Occupational exposure to styrene: modulation of cytogenetic damage and levels of urinary metabolites of styrene by polymorphisms in genes CYP2E1, EPHX1, GSTM1, GSTT1 and GSTP1.
Toxicology 2004;195(2-3):231-42.
2004: Jose Maria Eirín-López; M Fernanda Ruiz; Ana M González-Tizón; Andrés Martínez; Lucas Sánchez; Josefina Méndez
Molecular evolutionary characterization of the mussel Mytilus histone multigene family: first record of a tandemly repeated unit of five histone genes containing an H1 subtype with "orphon" features.
Journal of molecular evolution 2004;58(2):131-44.
2003: Ana Insua; María José López-Piñón; Ruth Freire; Josefina Méndez
Sequence analysis of the ribosomal DNA internal transcribed spacer region in some scallop species (Mollusca: Bivalvia: Pectinidae).
Genome / National Research Council Canada = Génome / Conseil national de recherches Canada 2003;46(4):595-604.
2003: Blanca Laffon; Beatriz Pérez-Cadahía; Eduardo Pásaro; Josefina Méndez
Effect of epoxide hydrolase and glutathione S-tranferase genotypes on the induction of micronuclei and DNA damage by styrene-7,8-oxide in vitro.
Mutation research 2003;536(1-2):49-59.
2003: Blanca Laffon; Beatriz Pérez-Cadahía; Eduardo Pásaro; Josefina Méndez
Individual sensitivity to DNA damage induced by styrene in vitro: influence of cytochrome p450, epoxide hydrolase and glutathione S-transferase genotypes.
Toxicology 2003;186(1-2):131-41.
2003: J Fernández-Tajes; Ana M González-Tizón; Andrés Martínez-Lage; Josefina Méndez
Cytogenetics of the razor clam Solen marginatus (Mollusca: Bivalvia: Solenidae).
Cytogenetic and genome research 2003;101(1):43-6.
2002: María José López-Piñón; Ana Insua; Josefina Méndez
Identification of four scallop species using PCR and restriction analysis of the ribosomal DNA internal transcribed spacer region.
Marine biotechnology (New York, N.Y.) 2002;4(5):495-502.
2002: Andrés Martínez-Lage; F Rodríguez; Ana M González-Tizón; Eva Prats; Luis Cornudella; Josefina Méndez
Comparative analysis of different satellite DNAs in four Mytilus species.
Genome / National Research Council Canada = Génome / Conseil national de recherches Canada 2002;45(5):922-9.
2002: Jose Maria Eirín-López; Ana M González-Tizón; Andrés Martinez; Josefina Méndez
Molecular and evolutionary analysis of mussel histone genes (Mytilus spp.): possible evidence of an "orphon origin" for H1 histone genes.
Journal of molecular evolution 2002;55(3):272-83.
2002: Ignacio Rego; Andrés Martínez; Ana M González-Tizón; Juan M Vieites; Francisco Leira; Josefina Méndez
PCR technique for identification of mussel species.
Journal of agricultural and food chemistry 2002;50(7):1780-4.
2002: Blanca Laffon; Eduardo Pásaro; Josefina Méndez
Evaluation of genotoxic effects in a group of workers exposed to low levels of styrene.
Toxicology 2002;171(2-3):175-86.
2002: Blanca Laffon; Eduardo Pásaro; Josefina Méndez
DNA damage and repair in human leukocytes exposed to styrene-7,8-oxide measured by the comet assay.
Toxicology letters 2002;126(1):61-8.
2001: Blanca Laffon; Eduardo Pásaro; Josefina Méndez
Genotoxic effects of styrene-7,8-oxide in human white blood cells: comet assay in relation to the induction of sister-chromatid exchanges and micronuclei.
Mutation research 2001;491(1-2):163-72.
2001: Blanca Laffon; Eduardo Pásaro; Josefina Méndez
Effects of styrene-7,8-oxide over p53, p21, bcl-2 and bax expression in human lymphocyte cultures.
Mutagenesis 2001;16(2):127-32.
2001: Ana Insua; Ruth Freire; J Ríos; Josefina Méndez
The 5S rDNA of mussels Mytilus galloprovincialis and M. edulis: sequence variation and chromosomal location.
Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology 2001;9(6):495-505.
2000: Ana M González-Tizón; Andrés Martínez-Lage; I Rego; Juan Ausió; Josefina Méndez
DNA content, karyotypes, and chromosomal location of 18S-5.8S-28S ribosomal loci in some species of bivalve molluscs from the Pacific Canadian coast.
Genome / National Research Council Canada = Génome / Conseil national de recherches Canada 2000;43(6):1065-72.
2000: Ana M González-Tizón; Andrés Martínez-Lage; J Ausio; Josefina Méndez
Polyploidy in a natural population of mussel, Mytilus trossulus.
Genome / National Research Council Canada = Génome / Conseil national de recherches Canada 2000;43(2):409-11.
1998: Ana Insua; María José López-Piñón; Josefina Méndez
Characterization of Aequipecten opercularis (Bivalvia: Pectinidae) chromosomes by different staining techniques and fluorescent in situ hybridization.
Genes & genetic systems 1998;73(4):193-200.
1998: Ana Insua; Josefina Méndez
Physical mapping and activity of ribosomal RNA genes in mussel Mytilus galloprovincialis.
Hereditas 1998;128(3):189-94.